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Prescott Woodruff, MD, MPH

TitleProfessor
SchoolUCSF School of Medicine
DepartmentMedicine
Address513 Parnassus Ave
San Francisco CA 94143
Phone415-514-2061
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    Collapse Biography 
    Collapse Education and Training
    Columbia College of Physicians and SurgeonsMD1993Medicine
    Harvard School of Public HealthMPH1996
    Collapse Awards and Honors
    2012Elected to the American Society for Clinical Investigation
    1993AOA

    Collapse Overview 
    Collapse Overview
    Research Interests

    I. Mentoring in Translational Research
    Supported by K24HL137013, Mentoring research in precision medicine for lung disease.

    II. The identification of molecular sub-phenotypes of asthma and COPD:
    These studies are funded by:
    1) An R01 from the NIH/NHLBI, entitled “Molecular Phenotyping of Asthma” (R01 HL-095372) which has applied genomic analyses to airway samples from patients with asthma to distinguish Th2-driven and non-Th2-driven sub-phenotypes of asthma that have distinct clinical, pathological and treatment-related characteristics.

    2) The NHLBI SPIROMICS longitudinal study of COPD (R01HL137880). The goal of the Spiromics project is to identify molecular phenotypes of COPD and to link these phenotypes to disease progression and exacerbations.

    III. Mechanisms of airway inflammation and remodeling in lung diseases:
    These studies apply innovative methods for quantitative morphometry and gene expression analyses to human tissue samples obtained at fiberoptic bronchoscopy. In work to date, we have applied these methods to study mechanisms of disease in asthma, COPD and sarcoidosis.

    IV. Development of blood-based diagnostic tests for lung disease using genomic approaches:
    These studies apply gene expression profiling and miRNA profiling in blood cells and plasma/serum to develop diagnostic tests in asthma, COPD and sarcoidosis and are supported by U01HL126493, Defining A Comprehensive Reference Profile of Circulating Human Extracellular RNA.

    V. Clinical Trials in asthma and COPD
    Ongoing: U01HL128952, Redefining Therapy In Early COPD: RETHINC


    Collapse Research 
    Collapse Research Activities and Funding
    SPIROMICS II: Biological underpinnings of COPD heterogeneity and progression
    NIH/NHLBI U01HL137880Sep 15, 2017 - May 31, 2022
    Role: Principal Investigator
    Mentoring research in precision medicine for lung disease
    NIH/NHLBI K24HL137013Apr 28, 2017 - Mar 31, 2022
    Role: Principal Investigator
    Redefining Therapy In Early COPD: RETHINC
    NIH/NHLBI U01HL128952Sep 9, 2015 - Jul 31, 2019
    Role: Co-Principal Investigator
    Defining A Comprehensive Reference Profile of Circulating Human Extracellular RNA
    NIH/NHLBI U01HL126493Aug 1, 2014 - Apr 30, 2019
    Role: Principal Investigator
    INNATE AND ADAPTIVE IMMUNE RESPONSES IN TH2-HIGH ASTHMA
    NIH/NHLBI P01HL107202Aug 15, 2012 - May 31, 2017
    Role: Co-Investigator
    Role of Th2 and non-Th2 Inflammation in Airway Smooth Muscle Remodeling in Asthma
    NIH/NHLBI R01HL097591Aug 1, 2009 - Jul 31, 2014
    Role: Principal Investigator
    SPIROMICS
    NIH 268200900014C-10-0-4Feb 2, 2009 - Jun 30, 2016
    Role: Principal Investigator
    SPIRIOMICS Clinical Center
    NIH/NHLBI 268200900014C-5-0-2Feb 2, 2009 - Jun 30, 2016
    Role: Principal Investigator
    SPIROMICS Clinical Center
    NIH/NHLBI 268200900014C-3-0-1Feb 2, 2009 - Dec 31, 2015
    Role: Principal Investigator
    SPIRIOMICS Clinical Center
    NIH/NHLBI 268200900014C-3-0-2Feb 2, 2009 - Dec 31, 2015
    Role: Principal Investigator
    SPIROMICS Clinical Center
    NIH/NHLBI 268200900014C-0-0-1Feb 1, 2009 - Jan 31, 2016
    Role: Principal Investigator
    Molecular Phenotyping of Asthma
    NIH/NHLBI R01HL095372Sep 24, 2008 - Jul 31, 2013
    Role: Principal Investigator
    IL-13 and IL-17 dynamics in the asthmatic airway
    NIH/NIAID U19AI077439Apr 1, 2008 - Mar 31, 2018
    Role: Co-Investigator
    TITLE: SUB POPULATIONS AND INTERMEDIATE OUTCOMES MEASURES IN COPD STUDY (SPIROMICS) - GENOMICS & INFORMATICS CENTER
    NIH/NHLBI N01HR000000Oct 31, 2006 - Apr 30, 2017
    Role: Co-Principal Investigator
    MECHANISMS OF SMOOTH MUSCLE HYPERREACTIVITY ON ASTHMA
    NIH/NCRR K23RR017002May 15, 2002 - Apr 30, 2008
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse In The News
    Collapse Clinical Trials
    Collapse Global Health
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Bhakta NR, Christenson SA, Nerella S, Solberg OD, Nguyen CP, Choy DF, Jung KL, Garudadri S, Bonser LR, Pollack JL, Zlock LT, Erle DJ, Langelier C, Derisi JL, Arron JR, Fahy JV, Woodruff P. Interferon-stimulated Gene Expression, Type-2 Inflammation and Endoplasmic Reticulum Stress in Asthma. Am J Respir Crit Care Med. 2017 Oct 24. PMID: 29064281.
      View in: PubMed
    2. Anderson WH, Ha JW, Couper DJ, O'Neal WK, Barr RG, Bleecker ER, Carretta EE, Cooper CB, Doerschuk CM, Drummond MB, Han MK, Hansel NN, Kim V, Kleerup EC, Martinez FJ, Rennard SI, Tashkin D, Woodruff P, Paine R, Curtis JL, Kanner RE. Variability in objective and subjective measures affects baseline values in studies of patients with COPD. PLoS One. 2017; 12(9):e0184606. PMID: 28934249.
      View in: PubMed
    3. Martinez CH, Li SX, Hirzel AJ, Stolberg VR, Alexis NE, Barr RG, Bleecker ER, Carretta EE, Christenson SA, Cooper CB, Couper DJ, Doerschuk CM, Han MK, Hansel NN, Hastie AT, Hoffman EA, Kaner RJ, Martinez FJ, Meyers DA, O'Neal WK, Paine R, Putcha N, Rennard SI, Woodruff P, Zeidler M, Curtis JL, Freeman CM. Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort. J Allergy Clin Immunol. 2017 Sep 12. PMID: 28916185.
      View in: PubMed
    4. Kesimer M, Ford AA, Ceppe A, Radicioni G, Cao R, Davis CW, Doerschuk CM, Alexis NE, Anderson WH, Henderson AG, Barr RG, Bleecker ER, Christenson SA, Cooper CB, Han MK, Hansel NN, Hastie AT, Hoffman EA, Kanner RE, Martinez F, Paine R, Woodruff P, O'Neal WK, Boucher RC. Airway Mucin Concentration as a Marker of Chronic Bronchitis. N Engl J Med. 2017 09 07; 377(10):911-922. PMID: 28877023.
      View in: PubMed
    5. Lachowicz-Scroggins ME, Finkbeiner WE, Gordon ED, Yuan S, Zlock L, Bhakta NR, Woodruff P, Fahy JV, Boushey HA. Corticosteroid and long-acting ß-agonist therapy reduces epithelial goblet cell metaplasia. Clin Exp Allergy. 2017 Aug 22. PMID: 28833774.
      View in: PubMed
    6. Woodruff P, van den Berge M, Boucher RC, Brightling C, Burchard EG, Christenson SA, Han MK, Holtzman MJ, Kraft M, Lynch DA, Martinez FD, Reddel HK, Sin DD, Washko GR, Wenzel SE, Punturieri A, Freemer MM, Wise RA. American Thoracic Society/National Heart, Lung, and Blood Institute Asthma-Chronic Obstructive Pulmonary Disease Overlap Workshop Report. Am J Respir Crit Care Med. 2017 Aug 01; 196(3):375-381. PMID: 28636425.
      View in: PubMed
    7. Han MK, Quibrera PM, Carretta EE, Barr RG, Bleecker ER, Bowler RP, Cooper CB, Comellas A, Couper DJ, Curtis JL, Criner G, Dransfield MT, Hansel NN, Hoffman EA, Kanner RE, Krishnan JA, Martinez CH, Pirozzi CB, O'Neal WK, Rennard S, Tashkin DP, Wedzicha JA, Woodruff P, Paine R, Martinez FJ. Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort. Lancet Respir Med. 2017 Aug; 5(8):619-626. PMID: 28668356.
      View in: PubMed
    8. Duffy S, Marron R, Voelker H, Albert R, Connett J, Bailey W, Casaburi R, Cooper JA, Curtis JL, Dransfield M, Han MK, Make B, Marchetti N, Martinez F, Lazarus S, Niewoehner D, Scanlon PD, Sciurba F, Scharf S, Reed RM, Washko G, Woodruff P, McEvoy C, Aaron S, Sin D, Criner GJ. Effect of beta-blockers on exacerbation rate and lung function in chronic obstructive pulmonary disease (COPD). Respir Res. 2017 Jun 19; 18(1):124. PMID: 28629419.
      View in: PubMed
    9. Ra SW, Sze MA, Lee EC, Tam S, Oh Y, Fishbane N, Criner GJ, Woodruff P, Lazarus SC, Albert R, Connett JE, Han MK, Martinez FJ, Aaron SD, Reed RM, Man SFP, Sin DD. Azithromycin and risk of COPD exacerbations in patients with and without Helicobacter pylori. Respir Res. 2017 May 30; 18(1):109. PMID: 28558695.
      View in: PubMed
    10. Martinez CH, Murray S, Barr RG, Bleecker E, Bowler RP, Christenson SA, Comellas AP, Cooper CB, Couper D, Criner GJ, Curtis JL, Dransfield MT, Hansel NN, Hoffman EA, Kanner RE, Kleerup E, Krishnan JA, Lazarus SC, Leidy NK, O'Neal W, Martinez FJ, Paine R, Rennard SI, Tashkin DP, Woodruff P, Han MK. Respiratory Symptoms Items from the COPD Assessment Test Identify Ever-Smokers with Preserved Lung Function at Higher Risk for Poor Respiratory Outcomes. An Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort. Ann Am Thorac Soc. 2017 May; 14(5):636-642. PMID: 28459622.
      View in: PubMed
    11. Leitao Filho FS, Won Ra S, Mattman A, Schellenberg RS, Fishbane N, Criner GJ, Woodruff P, Lazarus SC, Albert R, Connett JE, Han MK, Martinez FJ, Leung JM, Paul Man SF, Aaron SD, Reed RM, Sin DD. Serum IgG and risk of exacerbations and hospitalizations in chronic obstructive pulmonary disease. J Allergy Clin Immunol. 2017 Apr 27. PMID: 28456620.
      View in: PubMed
    12. Van Dyken SJ, Liang HE, Naikawadi RP, Woodruff P, Wolters PJ, Erle DJ, Locksley RM. Spontaneous Chitin Accumulation in Airways and Age-Related Fibrotic Lung Disease. Cell. 2017 Apr 20; 169(3):497-509.e13. PMID: 28431248.
      View in: PubMed
    13. Keene JD, Jacobson S, Kechris K, Kinney GL, Foreman MG, Doerschuk CM, Make BJ, Curtis JL, Rennard SI, Barr RG, Bleecker ER, Kanner RE, Kleerup EC, Hansel NN, Woodruff P, Han MK, Paine R, Martinez FJ, Bowler RP, O'Neal WK. Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts. Am J Respir Crit Care Med. 2017 Feb 15; 195(4):473-481. PMID: 27579823.
      View in: PubMed
    14. Martinez CH, Diaz AA, Meldrum C, Curtis JL, Cooper CB, Pirozzi C, Kanner RE, Paine Iii R, Woodruff P, Bleecker ER, Hansel NN, Barr RG, Marchetti N, Criner GJ, Kazerooni EA, Hoffman EA, Ross BD, Galban CJ, Cigolle CT, Martinez FJ, Han MK. Age and Small Airway Imaging Abnormalities in Subjects with and without Airflow Obstruction in SPIROMICS. Am J Respir Crit Care Med. 2017 Feb 15; 195(4):464-472. PMID: 27564413.
      View in: PubMed
    15. Hobbs BD, de Jong K, Lamontagne M, Bossé Y, Shrine N, Artigas MS, Wain LV, Hall IP, Jackson VE, Wyss AB, London SJ, North KE, Franceschini N, Strachan DP, Beaty TH, Hokanson JE, Crapo JD, Castaldi PJ, Chase RP, Bartz TM, Heckbert SR, Psaty BM, Gharib SA, Zanen P, Lammers JW, Oudkerk M, Groen HJ, Locantore N, Tal-Singer R, Rennard SI, Vestbo J, Timens W, Paré PD, Latourelle JC, Dupuis J, O'Connor GT, Wilk JB, Kim WJ, Lee MK, Oh YM, Vonk JM, de Koning HJ, Leng S, Belinsky SA, Tesfaigzi Y, Manichaikul A, Wang XQ, Rich SS, Barr RG, Sparrow D, Litonjua AA, Bakke P, Gulsvik A, Lahousse L, Brusselle GG, Stricker BH, Uitterlinden AG, Ampleford EJ, Bleecker ER, Woodruff P, Meyers DA, Qiao D, Lomas DA, Yim JJ, Kim DK, Hawrylkiewicz I, Sliwinski P, Hardin M, Fingerlin TE, Schwartz DA, Postma DS, MacNee W, Tobin MD, Silverman EK, Boezen HM, Cho MH. Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. Nat Genet. 2017 Mar; 49(3):426-432. PMID: 28166215.
      View in: PubMed
    16. Rodriguez-Roisin R, Han MK, Vestbo J, Wedzicha JA, Woodruff P, Martinez FJ. Chronic Respiratory Symptoms with Normal Spirometry. A Reliable Clinical Entity? Am J Respir Crit Care Med. 2017 Jan 01; 195(1):17-22. PMID: 27598473.
      View in: PubMed
    17. Sieren JP, Newell JD, Barr RG, Bleecker ER, Burnette N, Carretta EE, Couper D, Goldin J, Guo J, Han MK, Hansel NN, Kanner RE, Kazerooni EA, Martinez FJ, Rennard S, Woodruff P, Hoffman EA. SPIROMICS Protocol for Multicenter Quantitative Computed Tomography to Phenotype the Lungs. Am J Respir Crit Care Med. 2016 Oct 01; 194(7):794-806. PMID: 27482984.
      View in: PubMed
    18. Gulcev M, Reilly C, Griffin TJ, Broeckling CD, Sandri BJ, Witthuhn BA, Hodgson SW, Woodruff P, Wendt CH. Tryptophan catabolism in acute exacerbations of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2016; 11:2435-2446. PMID: 27729784.
      View in: PubMed
    19. Woodruff P, Couper D, Han MK. Symptoms in Smokers with Preserved Pulmonary Function. N Engl J Med. 2016 Sep 01; 375(9):896-7. PMID: 27606380.
      View in: PubMed
    20. Sun W, Kechris K, Jacobson S, Drummond MB, Hawkins GA, Yang J, Chen TH, Quibrera PM, Anderson W, Barr RG, Basta PV, Bleecker ER, Beaty T, Casaburi R, Castaldi P, Cho MH, Comellas A, Crapo JD, Criner G, Demeo D, Christenson SA, Couper DJ, Curtis JL, Doerschuk CM, Freeman CM, Gouskova NA, Han MK, Hanania NA, Hansel NN, Hersh CP, Hoffman EA, Kaner RJ, Kanner RE, Kleerup EC, Lutz S, Martinez FJ, Meyers DA, Peters SP, Regan EA, Rennard SI, Scholand MB, Silverman EK, Woodruff P, O'Neal WK, Bowler RP. Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD. PLoS Genet. 2016 Aug; 12(8):e1006011. PMID: 27532455; PMCID: PMC4988780.
    21. Wan XC, Woodruff P. Biomarkers in Severe Asthma. Immunol Allergy Clin North Am. 2016 Aug; 36(3):547-57. PMID: 27401625.
      View in: PubMed
    22. Gordon ED, Simpson LJ, Rios CL, Ringel L, Lachowicz-Scroggins ME, Peters MC, Wesolowska-Andersen A, Gonzalez JR, MacLeod HJ, Christian LS, Yuan S, Barry L, Woodruff P, Ansel KM, Nocka K, Seibold MA, Fahy JV, et al. Alternative splicing of interleukin-33 and type 2 inflammation in asthma. Proc Natl Acad Sci U S A. 2016 Aug 02; 113(31):8765-70. PMID: 27432971; PMCID: PMC4978244.
    23. Peters MC, McGrath KW, Hawkins GA, Hastie AT, Levy BD, Israel E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Holguin F, Wenzel SE, Woodruff P, Bleecker ER, Fahy JV, et al. Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts. Lancet Respir Med. 2016 Jul; 4(7):574-84. PMID: 27283230; PMCID: PMC5007068 [Available on 07/01/17].
    24. Ramstein J, Broos CE, Simpson LJ, Ansel KM, Sun SA, Ho ME, Woodruff P, Bhakta NR, Christian L, Nguyen CP, Antalek BJ, Benn BS, Hendriks RW, van den Blink B, Kool M, Koth LL. IFN-?-Producing T-Helper 17.1 Cells Are Increased in Sarcoidosis and Are More Prevalent than T-Helper Type 1 Cells. Am J Respir Crit Care Med. 2016 Jun 01; 193(11):1281-91. PMID: 26649486; PMCID: PMC4910899 [Available on 06/01/17].
    25. Brownell R, Kaminski N, Woodruff P, Bradford WZ, Richeldi L, Martinez FJ, Collard HR. Precision Medicine: The New Frontier in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2016 Jun 01; 193(11):1213-8. PMID: 26991475.
      View in: PubMed
    26. Woodruff P, Barr RG, Bleecker E, Christenson SA, Couper D, Curtis JL, Gouskova NA, Hansel NN, Hoffman EA, Kanner RE, Kleerup E, Lazarus SC, Martinez FJ, Paine R, Rennard S, Tashkin DP, Han MK. Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function. N Engl J Med. 2016 May 12; 374(19):1811-21. PMID: 27168432; PMCID: PMC4968204 [Available on 11/12/16].
    27. Putcha N, Barr RG, Han MK, Woodruff P, Bleecker ER, Kanner RE, Martinez FJ, Smith BM, Tashkin DP, Bowler RP, Eisner MD, Rennard SI, Wise RA, Hansel NN. Understanding the impact of second-hand smoke exposure on clinical outcomes in participants with COPD in the SPIROMICS cohort. Thorax. 2016 Mar 09. PMID: 26962015.
      View in: PubMed
    28. Levy BD, Noel PJ, Freemer MM, Cloutier MM, Georas SN, Jarjour NN, Ober C, Woodruff P, Barnes KC, Bender BG, Camargo CA, Chupp GL, Denlinger LC, Fahy JV, Fitzpatrick AM, Fuhlbrigge A, Gaston BM, Hartert TV, Kolls JK, Lynch SV, Moore WC, Morgan WJ, Nadeau KC, Ownby DR, Solway J, Szefler SJ, Wenzel SE, Wright RJ, Smith RA, Erzurum SC. Future Research Directions in Asthma. An NHLBI Working Group Report. Am J Respir Crit Care Med. 2015 Dec 01; 192(11):1366-72. PMID: 26305520; PMCID: PMC4731702 [Available on 12/01/16].
    29. Hoffman SM, Chapman DG, Lahue KG, Cahoon JM, Rattu GK, Daphtary N, Aliyeva M, Fortner KA, Erzurum SC, Comhair SA, Woodruff P, Bhakta N, Dixon AE, Irvin CG, Janssen-Heininger YM, Poynter ME, Anathy V. Protein disulfide isomerase-endoplasmic reticulum resident protein 57 regulates allergen-induced airways inflammation, fibrosis, and hyperresponsiveness. J Allergy Clin Immunol. 2016 Mar; 137(3):822-32.e7. PMID: 26435004; PMCID: PMC4597791 [Available on 03/01/17].
    30. Woodruff P, Agusti A, Roche N, Singh D, Martinez FJ. Current concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised management. Lancet. 2015 May 02; 385(9979):1789-98. PMID: 25943943; PMCID: PMC4869530.
    31. Christenson SA, Steiling K, van den Berge M, Hijazi K, Hiemstra PS, Postma DS, Lenburg ME, Spira A, Woodruff P. Asthma-COPD overlap. Clinical relevance of genomic signatures of type 2 inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2015 Apr 01; 191(7):758-66. PMID: 25611785; PMCID: PMC4407484.
    32. Kangelaris KN, Prakash A, Liu KD, Aouizerat B, Woodruff P, Erle DJ, Rogers A, Seeley EJ, Chu J, Liu T, Osterberg-Deiss T, Zhuo H, Matthay MA, Calfee CS. Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS. Am J Physiol Lung Cell Mol Physiol. 2015 Jun 01; 308(11):L1102-13. PMID: 25795726; PMCID: PMC4451399.
    33. Freeman CM, Crudgington S, Stolberg VR, Brown JP, Sonstein J, Alexis NE, Doerschuk CM, Basta PV, Carretta EE, Couper DJ, Hastie AT, Kaner RJ, O'Neal WK, Paine Iii R, Rennard SI, Shimbo D, Woodruff P, Zeidler M, Curtis JL. Design of a multi-center immunophenotyping analysis of peripheral blood, sputum and bronchoalveolar lavage fluid in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). J Transl Med. 2015 Jan 27; 13:19. PMID: 25622723; PMCID: PMC4314767.
    34. Simpson LJ, Patel S, Bhakta NR, Choy DF, Brightbill HD, Ren X, Wang Y, Pua HH, Baumjohann D, Montoya MM, Panduro M, Remedios KA, Huang X, Fahy JV, Arron JR, Woodruff P, Ansel KM. A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production. Nat Immunol. 2014 Dec; 15(12):1162-70. PMID: 25362490; PMCID: PMC4233009.
    35. Su R, Li MM, Bhakta NR, Solberg OD, Darnell EP, Ramstein J, Garudadri S, Ho M, Woodruff P, Koth LL. Longitudinal analysis of sarcoidosis blood transcriptomic signatures and disease outcomes. Eur Respir J. 2014 Oct; 44(4):985-93. PMID: 25142485.
      View in: PubMed
    36. Han MK, Tayob N, Murray S, Dransfield MT, Washko G, Scanlon PD, Criner GJ, Casaburi R, Connett J, Lazarus SC, Albert R, Woodruff P, Martinez FJ. Predictors of chronic obstructive pulmonary disease exacerbation reduction in response to daily azithromycin therapy. Am J Respir Crit Care Med. 2014 Jun 15; 189(12):1503-8. PMID: 24779680; PMCID: PMC4226018.
    37. Cohn L, Woodruff P. Update in asthma 2013. Am J Respir Crit Care Med. 2014 Jun 15; 189(12):1487-93. PMID: 24930529.
      View in: PubMed
    38. Greer AM, Matthay MA, Kukreja J, Bhakta NR, Nguyen CP, Wolters PJ, Woodruff P, Fahy JV, Shin JS. Accumulation of BDCA1? dendritic cells in interstitial fibrotic lung diseases and Th2-high asthma. PLoS One. 2014; 9(6):e99084. PMID: 24915147; PMCID: PMC4051692.
    39. Criner GJ, Connett JE, Aaron SD, Albert RK, Bailey WC, Casaburi R, Cooper JA, Curtis JL, Dransfield MT, Han MK, Make B, Marchetti N, Martinez FJ, Niewoehner DE, Scanlon PD, Sciurba FC, Scharf SM, Sin DD, Voelker H, Washko GR, Woodruff P, Lazarus SC. Simvastatin for the prevention of exacerbations in moderate-to-severe COPD. N Engl J Med. 2014 Jun 05; 370(23):2201-10. PMID: 24836125; PMCID: PMC4375247.
    40. Greer AM, Wu N, Putnam AL, Woodruff P, Wolters P, Kinet JP, Shin JS. Serum IgE clearance is facilitated by human FceRI internalization. J Clin Invest. 2014 Mar; 124(3):1187-98. PMID: 24569373; PMCID: PMC3938266.
    41. O'Neal WK, Anderson W, Basta PV, Carretta EE, Doerschuk CM, Barr RG, Bleecker ER, Christenson SA, Curtis JL, Han MK, Hansel NN, Kanner RE, Kleerup EC, Martinez FJ, Miller BE, Peters SP, Rennard SI, Scholand MB, Tal-Singer R, Woodruff P, Couper DJ, Davis SM. Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study. J Transl Med. 2014 Jan 08; 12:9. PMID: 24397870; PMCID: PMC3928911.
    42. Roy MG, Livraghi-Butrico A, Fletcher AA, McElwee MM, Evans SE, Boerner RM, Alexander SN, Bellinghausen LK, Song AS, Petrova YM, Tuvim MJ, Adachi R, Romo I, Bordt AS, Bowden MG, Sisson JH, Woodruff P, Thornton DJ, Rousseau K, De la Garza MM, Moghaddam SJ, Karmouty-Quintana H, Blackburn MR, Drouin SM, Davis CW, Terrell KA, Grubb BR, O'Neal WK, Flores SC, Cota-Gomez A, Lozupone CA, Donnelly JM, Watson AM, Hennessy CE, Keith RC, Yang IV, Barthel L, Henson PM, Janssen WJ, Schwartz DA, Boucher RC, Dickey BF, Evans CM. Muc5b is required for airway defence. Nature. 2014 Jan 16; 505(7483):412-6. PMID: 24317696; PMCID: PMC4001806.
    43. Woodruff P. Subtypes of asthma defined by epithelial cell expression of messenger RNA and microRNA. Ann Am Thorac Soc. 2013 Dec; 10 Suppl:S186-9. PMID: 24313771; PMCID: PMC3960987.
    44. Su R, Nguyen ML, Agarwal MR, Kirby C, Nguyen CP, Ramstein J, Darnell EP, Gomez AD, Ho M, Woodruff P, Koth LL. Interferon-inducible chemokines reflect severity and progression in sarcoidosis. Respir Res. 2013 Nov 07; 14:121. PMID: 24199653; PMCID: PMC4176097.
    45. Woodruff P, Chatila W, Connett JE, Criner GJ, Curtis JL, Dransfield MT, Han MK, Lazarus SC, Marchetti N, Rogers TJ, Scanlon PD, Sin DD, Voelker H, Wendt C, Albert RK. Tumour necrosis factor receptor-75 and risk of COPD exacerbation in the azithromycin trial. Eur Respir J. 2014 Jan; 43(1):295-8. PMID: 24136332; PMCID: PMC4326242.
    46. Peters MC, Mekonnen ZK, Yuan S, Bhakta NR, Woodruff P, Fahy JV. Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma. J Allergy Clin Immunol. 2014 Feb; 133(2):388-94. PMID: 24075231; PMCID: PMC3981552.
    47. Couper D, LaVange LM, Han M, Barr RG, Bleecker E, Hoffman EA, Kanner R, Kleerup E, Martinez FJ, Woodruff P, Rennard S. Design of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS). Thorax. 2014 May; 69(5):491-4. PMID: 24029743; PMCID: PMC3954445.
    48. Bhakta NR, Solberg OD, Nguyen CP, Nguyen CN, Arron JR, Fahy JV, Woodruff P. A qPCR-based metric of Th2 airway inflammation in asthma. Clin Transl Allergy. 2013 Jul 17; 3(1):24. PMID: 23866775; PMCID: PMC3724712.
    49. Woodruff P. Double-edged sword? JAMA Intern Med. 2013 Jul 08; 173(13):1184-5. PMID: 23689337.
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    50. Hallstrand TS, Lai Y, Altemeier WA, Appel CL, Johnson B, Frevert CW, Hudkins KL, Bollinger JG, Woodruff P, Hyde DM, Henderson WR, Gelb MH. Regulation and function of epithelial secreted phospholipase A2 group X in asthma. Am J Respir Crit Care Med. 2013 Jul 01; 188(1):42-50. PMID: 23614662; PMCID: PMC3735246.
    51. Levänen B, Bhakta NR, Torregrosa Paredes P, Barbeau R, Hiltbrunner S, Pollack JL, Sköld CM, Svartengren M, Grunewald J, Gabrielsson S, Eklund A, Larsson BM, Woodruff P, Erle DJ, Wheelock ÅM. Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients. J Allergy Clin Immunol. 2013 Mar; 131(3):894-903. PMID: 23333113; PMCID: PMC4013392.
    52. Kudo M, Khalifeh Soltani SM, Sakuma SA, McKleroy W, Lee TH, Woodruff P, Lee JW, Huang K, Chen C, Arjomandi M, Huang X, Atabai K. Mfge8 suppresses airway hyperresponsiveness in asthma by regulating smooth muscle contraction. Proc Natl Acad Sci U S A. 2013 Jan 08; 110(2):660-5. PMID: 23269839; PMCID: PMC3545777.
    53. Seumois G, Vijayanand P, Eisley CJ, Omran N, Kalinke L, North M, Ganesan AP, Simpson LJ, Hunkapiller N, Moltzahn F, Woodruff P, Fahy JV, Erle DJ, Djukanovic R, Blelloch R, Ansel KM. An integrated nano-scale approach to profile miRNAs in limited clinical samples. Am J Clin Exp Immunol. 2012 Nov 30; 1(2):70-89. PMID: 23304658.
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    54. Albert RK, Connett J, Curtis JL, Martinez FJ, Han MK, Lazarus SC, Woodruff P. Mannose-binding lectin deficiency and acute exacerbations of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2012; 7:767-77. PMID: 23226013; PMCID: PMC3514010.
    55. Huang F, Zhang H, Wu M, Yang H, Kudo M, Peters CJ, Woodruff P, Solberg OD, Donne ML, Huang X, Sheppard D, Fahy JV, Wolters PJ, Hogan BL, Finkbeiner WE, Li M, Jan YN, Jan LY, Rock JR. Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proc Natl Acad Sci U S A. 2012 Oct 02; 109(40):16354-9. PMID: 22988107; PMCID: PMC3479591.
    56. Solberg OD, Ostrin EJ, Love MI, Peng JC, Bhakta NR, Hou L, Nguyen C, Solon M, Nguyen C, Barczak AJ, Zlock LT, Blagev DP, Finkbeiner WE, Ansel KM, Arron JR, Erle DJ, Woodruff P. Airway epithelial miRNA expression is altered in asthma. Am J Respir Crit Care Med. 2012 Nov 15; 186(10):965-74. PMID: 22955319; PMCID: PMC3530212.
    57. Albert RK, Connett J, Woodruff P. Azithromycin and the risk of cardiovascular death. N Engl J Med. 2012 Aug 23; 367(8):773-4; author reply 775. PMID: 22913694.
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    58. Jia G, Erickson RW, Choy DF, Mosesova S, Wu LC, Solberg OD, Shikotra A, Carter R, Audusseau S, Hamid Q, Bradding P, Fahy JV, Woodruff P, Harris JM, Arron JR. Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients. J Allergy Clin Immunol. 2012 Sep; 130(3):647-654.e10. PMID: 22857879; PMCID: PMC3626285.
    59. Diez D, Goto S, Fahy JV, Erle DJ, Woodruff P, Wheelock ÅM, Wheelock CE. Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics. BMC Med Genomics. 2012 Jun 19; 5:27. PMID: 22713245; PMCID: PMC3408345.
    60. Dransfield MT, Harnden S, Burton RL, Albert RK, Bailey WC, Casaburi R, Connett J, Cooper JA, Criner GJ, Curtis JL, Han MK, Make B, Marchetti N, Martinez FJ, McEvoy C, Nahm MH, Niewoehner DE, Porszasz J, Reilly J, Scanlon PD, Scharf SM, Sciurba FC, Washko GR, Woodruff P, Lazarus SC. Long-term comparative immunogenicity of protein conjugate and free polysaccharide pneumococcal vaccines in chronic obstructive pulmonary disease. Clin Infect Dis. 2012 Sep; 55(5):e35-44. PMID: 22652582; PMCID: PMC3491850.
    61. Thomas MF, Abdul-Wajid S, Panduro M, Babiarz JE, Rajaram M, Woodruff P, Lanier LL, Heissmeyer V, Ansel KM. Eri1 regulates microRNA homeostasis and mouse lymphocyte development and antiviral function. Blood. 2012 Jul 05; 120(1):130-42. PMID: 22613798; PMCID: PMC3390952.
    62. Hallstrand TS, Woodruff P, Holgate ST, Knight DA. Function of the airway epithelium in asthma. J Allergy (Cairo). 2012; 2012:160586. PMID: 22536273; PMCID: PMC3321308.
    63. Barr RG, Berkowitz EA, Bigazzi F, Bode F, Bon J, Bowler RP, Chiles C, Crapo JD, Criner GJ, Curtis JL, Dass C, Dirksen A, Dransfield MT, Edula G, Erikkson L, Friedlander A, Galperin-Aizenberg M, Gefter WB, Gierada DS, Grenier PA, Goldin J, Han MK, Hanania NA, Hansel NN, Jacobson FL, Kauczor HU, Kinnula VL, Lipson DA, Lynch DA, MacNee W, Make BJ, Mamary AJ, Mann H, Marchetti N, Mascalchi M, McLennan G, Murphy JR, Naidich D, Nath H, Newell JD, Pistolesi M, Regan EA, Reilly JJ, Sandhaus R, Schroeder JD, Sciurba F, Shaker S, Sharafkhaneh A, Silverman EK, Steiner RM, Strange C, Sverzellati N, Tashjian JH, van Beek EJ, Washington L, Washko GR, Westney G, Wood SA, Woodruff P. A combined pulmonary-radiology workshop for visual evaluation of COPD: study design, chest CT findings and concordance with quantitative evaluation. COPD. 2012 Apr; 9(2):151-9. PMID: 22429093; PMCID: PMC3752926.
    64. Casaburi R, Porszasz J, Hecht A, Tiep B, Albert RK, Anthonisen NR, Bailey WC, Connett JE, Cooper JA, Criner GJ, Curtis J, Dransfield M, Lazarus SC, Make B, Martinez FJ, McEvoy C, Niewoehner DE, Reilly JJ, Scanlon P, Scharf SM, Sciurba FC, Woodruff P. Influence of lightweight ambulatory oxygen on oxygen use and activity patterns of COPD patients receiving long-term oxygen therapy. COPD. 2012 Feb; 9(1):3-11. PMID: 22292592.
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    65. Albert RK, Connett J, Bailey WC, Casaburi R, Cooper JA, Criner GJ, Curtis JL, Dransfield MT, Han MK, Lazarus SC, Make B, Marchetti N, Martinez FJ, Madinger NE, McEvoy C, Niewoehner DE, Porsasz J, Price CS, Reilly J, Scanlon PD, Sciurba FC, Scharf SM, Washko GR, Woodruff P, Anthonisen NR. Azithromycin for prevention of exacerbations of COPD. N Engl J Med. 2011 Aug 25; 365(8):689-98. PMID: 21864166; PMCID: PMC3220999.
    66. Gordon ED, Sidhu SS, Wang ZE, Woodruff P, Yuan S, Solon MC, Conway SJ, Huang X, Locksley RM, Fahy JV. A protective role for periostin and TGF-ß in IgE-mediated allergy and airway hyperresponsiveness. Clin Exp Allergy. 2012 Jan; 42(1):144-55. PMID: 22093101; PMCID: PMC3271792.
    67. Koth LL, Solberg OD, Peng JC, Bhakta NR, Nguyen CP, Woodruff P. Sarcoidosis blood transcriptome reflects lung inflammation and overlaps with tuberculosis. Am J Respir Crit Care Med. 2011 Nov 15; 184(10):1153-63. PMID: 21852540; PMCID: PMC3262024.
    68. Woodruff P. Novel outcomes and end points: biomarkers in chronic obstructive pulmonary disease clinical trials. Proc Am Thorac Soc. 2011 Aug; 8(4):350-5. PMID: 21816991; PMCID: PMC3209575.
    69. Bhakta NR, Woodruff P. Human asthma phenotypes: from the clinic, to cytokines, and back again. Immunol Rev. 2011 Jul; 242(1):220-32. PMID: 21682748; PMCID: PMC3391010.
    70. Woodruff P, Albert RK, Bailey WC, Casaburi R, Connett JE, Cooper JA, Criner GJ, Curtis JL, Dransfield MT, Han MK, Harnden SM, Kim V, Marchetti N, Martinez FJ, McEvoy CE, Niewoehner DE, Reilly JJ, Rice K, Scanlon PD, Scharf SM, Sciurba FC, Washko GR, Lazarus SC. Randomized trial of zileuton for treatment of COPD exacerbations requiring hospitalization. COPD. 2011 Feb; 8(1):21-9. PMID: 21299475; PMCID: PMC3775706.
    71. Choy DF, Modrek B, Abbas AR, Kummerfeld S, Clark HF, Wu LC, Fedorowicz G, Modrusan Z, Fahy JV, Woodruff P, Arron JR. Gene expression patterns of Th2 inflammation and intercellular communication in asthmatic airways. J Immunol. 2011 Feb 01; 186(3):1861-9. PMID: 21187436; PMCID: PMC3981556.
    72. Innes AL, McGrath KW, Dougherty RH, McCulloch CE, Woodruff P, Seibold MA, Okamoto KS, Ingmundson KJ, Solon MC, Carrington SD, Fahy JV. The H antigen at epithelial surfaces is associated with susceptibility to asthma exacerbation. Am J Respir Crit Care Med. 2011 Jan 15; 183(2):189-94. PMID: 20732988; PMCID: PMC3040389.
    73. Sidhu SS, Yuan S, Innes AL, Kerr S, Woodruff P, Hou L, Muller SJ, Fahy JV. Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma. Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32):14170-5. PMID: 20660732; PMCID: PMC2922596.
    74. Dougherty RH, Sidhu SS, Raman K, Solon M, Solberg OD, Caughey GH, Woodruff P, Fahy JV. Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma. J Allergy Clin Immunol. 2010 May; 125(5):1046-1053.e8. PMID: 20451039; PMCID: PMC2918406.
    75. Koth LL, Cambier CJ, Ellwanger A, Solon M, Hou L, Lanier LL, Abram CL, Hamerman JA, Woodruff P. DAP12 is required for macrophage recruitment to the lung in response to cigarette smoke and chemotaxis toward CCL2. J Immunol. 2010 Jun 01; 184(11):6522-8. PMID: 20421649; PMCID: PMC4091814.
    76. Woodruff P, Wolff M, Hohlfeld JM, Krug N, Dransfield MT, Sutherland ER, Criner GJ, Kim V, Prasse A, Nivens MC, Tetzlaff K, Heilker R, Fahy JV. Safety and efficacy of an inhaled epidermal growth factor receptor inhibitor (BIBW 2948 BS) in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2010 Mar 01; 181(5):438-45. PMID: 20007923.
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    77. Park SW, Verhaeghe C, Nguyenvu LT, Barbeau R, Eisley CJ, Nakagami Y, Huang X, Woodruff P, Fahy JV, Erle DJ. Distinct roles of FOXA2 and FOXA3 in allergic airway disease and asthma. Am J Respir Crit Care Med. 2009 Oct 01; 180(7):603-10. PMID: 19628779; PMCID: PMC2753788.
    78. Dransfield MT, Nahm MH, Han MK, Harnden S, Criner GJ, Martinez FJ, Scanlon PD, Woodruff P, Washko GR, Connett JE, Anthonisen NR, Bailey WC. Superior immune response to protein-conjugate versus free pneumococcal polysaccharide vaccine in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2009 Sep 15; 180(6):499-505. PMID: 19556517; PMCID: PMC2742743.
    79. Woodruff P, Modrek B, Choy DF, Jia G, Abbas AR, Ellwanger A, Koth LL, Arron JR, Fahy JV. T-helper type 2-driven inflammation defines major subphenotypes of asthma. Am J Respir Crit Care Med. 2009 Sep 01; 180(5):388-95. PMID: 19483109; PMCID: PMC2742757.
    80. Woodruff P, Ellwanger A, Solon M, Cambier CJ, Pinkerton KE, Koth LL. Alveolar macrophage recruitment and activation by chronic second hand smoke exposure in mice. COPD. 2009 Apr; 6(2):86-94. PMID: 19378221; PMCID: PMC2873864.
    81. Goswami S, Angkasekwinai P, Shan M, Greenlee KJ, Barranco WT, Polikepahad S, Seryshev A, Song LZ, Redding D, Singh B, Sur S, Woodruff P, Dong C, Corry DB, Kheradmand F. Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma. Nat Immunol. 2009 May; 10(5):496-503. PMID: 19329997.
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    82. Habets P, Krabbendam L, Hofman P, Suckling J, Oderwald F, Bullmore E, Woodruff P, Van Os J, Marcelis M. Cognitive performance and grey matter density in psychosis: functional relevance of a structural endophenotype. Neuropsychobiology. 2008; 58(3-4):128-37. PMID: 19088490.
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    83. Seibold MA, Donnelly S, Solon M, Innes A, Woodruff P, Boot RG, Burchard EG, Fahy JV. Chitotriosidase is the primary active chitinase in the human lung and is modulated by genotype and smoking habit. J Allergy Clin Immunol. 2008 Nov; 122(5):944-950.e3. PMID: 18845328; PMCID: PMC2666777.
    84. Schane RE, Walter LC, Dinno A, Covinsky KE, Woodruff P. Prevalence and risk factors for depressive symptoms in persons with chronic obstructive pulmonary disease. J Gen Intern Med. 2008 Nov; 23(11):1757-62. PMID: 18690488; PMCID: PMC2585678.
    85. Woodruff P. Gene expression in asthmatic airway smooth muscle. Proc Am Thorac Soc. 2008 Jan 01; 5(1):113-8. PMID: 18094093; PMCID: PMC2645297.
    86. Panettieri RA, Kotlikoff MI, Gerthoffer WT, Hershenson MB, Woodruff P, Hall IP, Banks-Schlegel S. Airway smooth muscle in bronchial tone, inflammation, and remodeling: basic knowledge to clinical relevance. Am J Respir Crit Care Med. 2008 Feb 01; 177(3):248-52. PMID: 18006883; PMCID: PMC2218850.
    87. Woodruff P, Boushey HA, Dolganov GM, Barker CS, Yang YH, Donnelly S, Ellwanger A, Sidhu SS, Dao-Pick TP, Pantoja C, Erle DJ, Yamamoto KR, Fahy JV. Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids. Proc Natl Acad Sci U S A. 2007 Oct 02; 104(40):15858-63. PMID: 17898169; PMCID: PMC2000427.
    88. Innes AL, Woodruff P, Ferrando RE, Donnelly S, Dolganov GM, Lazarus SC, Fahy JV. Epithelial mucin stores are increased in the large airways of smokers with airflow obstruction. Chest. 2006 Oct; 130(4):1102-8. PMID: 17035444.
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    89. Woodruff P, Koth LL, Yang YH, Rodriguez MW, Favoreto S, Dolganov GM, Paquet AC, Erle DJ. A distinctive alveolar macrophage activation state induced by cigarette smoking. Am J Respir Crit Care Med. 2005 Dec 01; 172(11):1383-92. PMID: 16166618; PMCID: PMC2718436.
    90. Kuperman DA, Lewis CC, Woodruff P, Rodriguez MW, Yang YH, Dolganov GM, Fahy JV, Erle DJ. Dissecting asthma using focused transgenic modeling and functional genomics. J Allergy Clin Immunol. 2005 Aug; 116(2):305-11. PMID: 16083784.
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    91. Hays SR, Ferrando RE, Carter R, Wong HH, Woodruff P. Structural changes to airway smooth muscle in cystic fibrosis. Thorax. 2005 Mar; 60(3):226-8. PMID: 15741440; PMCID: PMC1747321.
    92. Kotlikoff MI, Kannan MS, Solway J, Deng KY, Deshpande DA, Dowell M, Feldman M, Green KS, Ji G, Johnston R, Lakser O, Lee J, Lund FE, Milla C, Mitchell RW, Nakai J, Rishniw M, Walseth TF, White TA, Wilson J, Xin HB, Woodruff P. Methodologic advancements in the study of airway smooth muscle. J Allergy Clin Immunol. 2004 Aug; 114(2 Suppl):S18-31. PMID: 15309016.
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    93. Kalayci O, Sonna LA, Woodruff P, Camargo CA, Luster AD, Lilly CM. Monocyte chemotactic protein-4 (MCP-4; CCL-13): a biomarker of asthma. J Asthma. 2004 Feb; 41(1):27-33. PMID: 15046375.
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    94. Woodruff P, Dolganov GM, Ferrando RE, Donnelly S, Hays SR, Solberg OD, Carter R, Wong HH, Cadbury PS, Fahy JV. Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression. Am J Respir Crit Care Med. 2004 May 01; 169(9):1001-6. PMID: 14726423.
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    95. Ferrando RE, Nyengaard JR, Hays SR, Fahy JV, Woodruff P. Applying stereology to measure thickness of the basement membrane zone in bronchial biopsy specimens. J Allergy Clin Immunol. 2003 Dec; 112(6):1243-5. PMID: 14657892.
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    96. Silverman RA, Boudreaux ED, Woodruff P, Clark S, Camargo CA. Cigarette smoking among asthmatic adults presenting to 64 emergency departments. Chest. 2003 May; 123(5):1472-9. PMID: 12740263.
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    97. Ferris TG, Blumenthal D, Woodruff P, Clark S, Camargo CA. Insurance and quality of care for adults with acute asthma. J Gen Intern Med. 2002 Dec; 17(12):905-13. PMID: 12472926; PMCID: PMC1495135.
    98. Weber EJ, Silverman RA, Callaham ML, Pollack CV, Woodruff P, Clark S, Camargo CA. A prospective multicenter study of factors associated with hospital admission among adults with acute asthma. Am J Med. 2002 Oct 01; 113(5):371-8. PMID: 12401531.
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    99. Pollack CV, Pollack ES, Baren JM, Smith SR, Woodruff P, Clark S, Camargo CA. A prospective multicenter study of patient factors associated with hospital admission from the emergency department among children with acute asthma. Arch Pediatr Adolesc Med. 2002 Sep; 156(9):934-40. PMID: 12197803.
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    100. Woodruff P, Fahy JV. Airway remodeling in asthma. Semin Respir Crit Care Med. 2002 Aug; 23(4):361-7. PMID: 16088629.
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    101. Woodruff P, Fahy JV. A role for neutrophils in asthma? Am J Med. 2002 Apr 15; 112(6):498-500. PMID: 11959064.
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    102. Hays SR, Woodruff P, Khashayar R, Ferrando RE, Liu J, Fung P, Zhao CQ, Wong HH, Fahy JV. Allergen challenge causes inflammation but not goblet cell degranulation in asthmatic subjects. J Allergy Clin Immunol. 2001 Nov; 108(5):784-90. PMID: 11692105.
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    103. Woodruff P, Khashayar R, Lazarus SC, Janson S, Avila P, Boushey HA, Segal M, Fahy JV. Relationship between airway inflammation, hyperresponsiveness, and obstruction in asthma. J Allergy Clin Immunol. 2001 Nov; 108(5):753-8. PMID: 11692100.
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    104. Hollyoak M, Woodruff P, Muller M, Daunt N, Weir P. Deep venous thrombosis in postoperative vascular surgical patients: a frequent finding without prophylaxis. J Vasc Surg. 2001 Oct; 34(4):656-60. PMID: 11668320.
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    105. Dolganov GM, Woodruff P, Novikov AA, Zhang Y, Ferrando RE, Szubin R, Fahy JV. A novel method of gene transcript profiling in airway biopsy homogenates reveals increased expression of a Na+-K+-Cl- cotransporter (NKCC1) in asthmatic subjects. Genome Res. 2001 Sep; 11(9):1473-83. PMID: 11544191.
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    106. Cydulka RK, Emerman CL, Rowe BH, Clark S, Woodruff P, Singh AK, Camargo CA. Differences between men and women in reporting of symptoms during an asthma exacerbation. Ann Emerg Med. 2001 Aug; 38(2):123-8. PMID: 11468605.
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    107. Woodruff P, Fahy JV. Asthma: prevalence, pathogenesis, and prospects for novel therapies. JAMA. 2001 Jul 25; 286(4):395-8. PMID: 11466111.
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    108. Zimmerman JL, Woodruff P, Clark S, Camargo CA. Relation between phase of menstrual cycle and emergency department visits for acute asthma. Am J Respir Crit Care Med. 2000 Aug; 162(2 Pt 1):512-5. PMID: 10934079.
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    109. Barr RG, Woodruff P, Clark S, Camargo CA. Sudden-onset asthma exacerbations: clinical features, response to therapy, and 2-week follow-up. Multicenter Airway Research Collaboration (MARC) investigators. Eur Respir J. 2000 Feb; 15(2):266-73. PMID: 10706490.
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    110. Lilly CM, Woodruff P, Camargo CA, Nakamura H, Drazen JM, Nadel ES, Hanrahan JP. Elevated plasma eotaxin levels in patients with acute asthma. J Allergy Clin Immunol. 1999 Oct; 104(4 Pt 1):786-90. PMID: 10518822.
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    111. Emond SD, Woodruff P, Lee EY, Singh AK, Camargo CA. Effect of an emergency department asthma program on acute asthma care. Ann Emerg Med. 1999 Sep; 34(3):321-5. PMID: 10459087.
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    112. Cydulka RK, Emerman CL, Schreiber D, Molander KH, Woodruff P, Camargo CA. Acute asthma among pregnant women presenting to the emergency department. Am J Respir Crit Care Med. 1999 Sep; 160(3):887-92. PMID: 10471614.
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    113. Singh AK, Cydulka RK, Stahmer SA, Woodruff P, Camargo CA. Sex differences among adults presenting to the emergency department with acute asthma. Multicenter Asthma Research Collaboration Investigators. Arch Intern Med. 1999 Jun 14; 159(11):1237-43. PMID: 10371232.
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    114. Emerman CL, Woodruff P, Cydulka RK, Gibbs MA, Pollack CV, Camargo CA. Prospective multicenter study of relapse following treatment for acute asthma among adults presenting to the emergency department. MARC investigators. Multicenter Asthma Research Collaboration. Chest. 1999 Apr; 115(4):919-27. PMID: 10208187.
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    115. Singh AK, Woodruff P, Ritz RH, Mitchell D, Camargo CA. Inhaled corticosteroids for asthma: are ED visits a missed opportunity for prevention? Am J Emerg Med. 1999 Mar; 17(2):144-7. PMID: 10102313.
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    116. Woodruff P, Emond SD, Singh AK, Camargo CA. Sudden-onset severe acute asthma: clinical features and response to therapy. Acad Emerg Med. 1998 Jul; 5(7):695-701. PMID: 9678394.
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    117. Takei N, Persaud R, Woodruff P, Brockington I, Murray RM. First episodes of psychosis in Afro-Caribbean and White people. An 18-year follow-up population-based study. Br J Psychiatry. 1998 Feb; 172:147-53. PMID: 9519067.
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    118. Furneaux HM, Rosenblum MK, Dalmau J, Wong E, Woodruff P, Graus F, Posner JB. Selective expression of Purkinje-cell antigens in tumor tissue from patients with paraneoplastic cerebellar degeneration. N Engl J Med. 1990 Jun 28; 322(26):1844-51. PMID: 2348838.
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    119. Hardie I, Strong R, Wall D, Petrie J, Rigby R, Lynch S, Woodruff P, Quinn J, Hirst G, Balderson G. Results of 1000 kidney transplants in Brisbane. Transplant Proc. 1989 Oct; 21(5):3775-6. PMID: 2815276.
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