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Epigenetic patient stratification via contrastive machine learning refines hallmark biomarkers in minoritized children with asthma. Res Sq. 2024 Sep 13.
Gorla A, Witonsky J, Elhawary JR, Chen ZJ, Mefford J, Perez-Garcia J, Huntsman S, Hu D, Eng C, Woodruff PG, Sankararaman S, Ziv E, Flint J, Zaitlen N, Burchard E, Rahmani E. PMID: 39315258; PMCID: PMC11419268.
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Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes. Nat Commun. 2024 May 24; 15(1):4417.
Keener R, Chhetri SB, Connelly CJ, Taub MA, Conomos MP, Weinstock J, Ni B, Strober B, Aslibekyan S, Auer PL, Barwick L, Becker LC, Blangero J, Bleecker ER, Brody JA, Cade BE, Celedon JC, Chang YC, Cupples LA, Custer B, Freedman BI, Gladwin MT, Heckbert SR, Hou L, Irvin MR, Isasi CR, Johnsen JM, Kenny EE, Kooperberg C, Minster RL, Naseri T, Viali S, Nekhai S, Pankratz N, Peyser PA, Taylor KD, Telen MJ, Wu B, Yanek LR, Yang IV, Albert C, Arnett DK, Ashley-Koch AE, Barnes KC, Bis JC, Blackwell TW, Boerwinkle E, Burchard EG, Carson AP, Chen Z, Chen YI, Darbar D, de Andrade M, Ellinor PT, Fornage M, Gelb BD, Gilliland FD, He J, Islam T, Kaab S, Kardia SLR, Kelly S, Konkle BA, Kumar R, Loos RJF, Martinez FD, McGarvey ST, Meyers DA, Mitchell BD, Montgomery CG, North KE, Palmer ND, Peralta JM, Raby BA, Redline S, Rich SS, Roden D, Rotter JI, Ruczinski I, Schwartz D, Sciurba F, Shoemaker MB, Silverman EK, Sinner MF, Smith NL, Smith AV, Tiwari HK, Vasan RS, Weiss ST, Williams LK, Zhang Y, Ziv E, Raffield LM, Reiner AP, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Hematology and Hemostasis Working Group, TOPMed Structural Variation Working Group, Arvanitis M, Greider CW, Mathias RA, Battle A. PMID: 38789417; PMCID: PMC11126610.
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1 Fields:
Translation:
HumansCells
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5-HTP inhibits eosinophilia via intracellular endothelial 5-HTRs; SNPs in 5-HTRs associate with asthmatic lung function. Front Allergy. 2024; 5:1385168.
Walker MT, Bloodworth JC, Kountz TS, McCarty SL, Green JE, Ferrie RP, Campbell JA, Averill SH, Beckman KB, Grammer LC, Eng C, Avila PC, Farber HJ, Rodriguez-Cintron W, Rodriguez-Santana JR, Serebrisky D, Thyne SM, Seibold MA, Burchard EG, Kumar R, Cook-Mills JM. PMID: 38845678; PMCID: PMC11153829.
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Implications of Race Adjustment in Lung-Function Equations. N Engl J Med. 2024 Jun 13; 390(22):2083-2097.
Diao JA, He Y, Khazanchi R, Nguemeni Tiako MJ, Witonsky JI, Pierson E, Rajpurkar P, Elhawary JR, Melas-Kyriazi L, Yen A, Martin AR, Levy S, Patel CJ, Farhat M, Borrell LN, Cho MH, Silverman EK, Burchard EG, Manrai AK. PMID: 38767252; PMCID: PMC11305821.
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6 Fields:
Translation:
Humans
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A common polymorphism in the Intelectin-1 gene influences mucus plugging in severe asthma. Nat Commun. 2024 May 09; 15(1):3900.
Everman JL, Sajuthi SP, Liegeois MA, Jackson ND, Collet EH, Peters MC, Chioccioli M, Moore CM, Patel BB, Dyjack N, Powell R, Rios C, Montgomery MT, Eng C, Elhawary JR, Mak ACY, Hu D, Huntsman S, Salazar S, Feriani L, Fairbanks-Mahnke A, Zinnen GL, Michel CR, Gomez J, Zhang X, Medina V, Chu HW, Cicuta P, Gordon ED, Zeitlin P, Ortega VE, Reisdorph N, Dunican EM, Tang M, Elicker BM, Henry TS, Bleecker ER, Castro M, Erzurum SC, Israel E, Levy BD, Mauger DT, Meyers DA, Sumino K, Gierada DS, Hastie AT, Moore WC, Denlinger LC, Jarjour NN, Schiebler ML, Wenzel SE, Woodruff PG, Rodriguez-Santana J, Pearson CG, Burchard EG, Fahy JV, Seibold MA. PMID: 38724552; PMCID: PMC11082194.
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HumansCells
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Advancing genomics to improve health equity. Nat Genet. 2024 May; 56(5):752-757.
Madden EB, Hindorff LA, Bonham VL, Akintobi TH, Burchard EG, Baker KE, Begay RL, Carpten JD, Cox NJ, Di Francesco V, Dillard DA, Fletcher FE, Fullerton SM, Garrison NA, Hammack-Aviran CM, Hiratsuka VY, Hildreth JEK, Horowitz CR, Hughes Halbert CA, Inouye M, Jackson A, Landry LG, Kittles RA, Leek JT, Limdi NA, Lockhart NC, Ofili EO, Pérez-Stable EJ, Sabatello M, Saulsberry L, Schools LE, Troyer JL, Wilfond BS, Wojcik GL, Cho JH, Lee SS, Green ED. PMID: 38684898; PMCID: PMC11096049.
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6 Fields:
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Humans
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The Puerto Rican Infant Metagenomic and Epidemiologic Study of Respiratory Outcomes (PRIMERO): Design and Baseline Characteristics for a Birth Cohort Study of Early-life Viral Respiratory Illnesses and Airway Dysfunction in Puerto Rican Children. medRxiv. 2024 Apr 16.
Witonsky JI, Elhawary JR, Eng C, Oh SS, Salazar S, Contreras MG, Medina V, Secor EA, Zhang P, Everman JL, Fairbanks-Mahnke A, Pruesse E, Sajuthi SP, Chang CH, Guerrero TR, Fuentes KC, Lopez N, Montanez-Lopez CA, Otero RA, Rivera RC, Rodriguez L, Vazquez G, Hu D, Huntsman S, Jackson ND, Li Y, Morin A, Nieves NA, Rios C, Serrano G, Williams BJM, Ziv E, Moore CM, Sheppard D, Burchard EG, Seibold MA, Rodriguez Santana JR. PMID: 38699325; PMCID: PMC11065009.
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A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children. Cell Genom. 2024 Apr 10; 4(4):100526.
de Smith AJ, Wahlster L, Jeon S, Kachuri L, Black S, Langie J, Cato LD, Nakatsuka N, Chan TF, Xia G, Mazumder S, Yang W, Gazal S, Eng C, Hu D, Burchard EG, Ziv E, Metayer C, Mancuso N, Yang JJ, Ma X, Wiemels JL, Wiemels JL, Yu F, Chiang CWK, Sankaran VG. PMID: 38537633; PMCID: PMC11019360.
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1 Fields:
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Humans
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Novel insights into the whole-blood DNA methylome of asthma in ethnically diverse children and youth. Eur Respir J. 2023 12; 62(6).
Herrera-Luis E, Rosa-Baez C, Huntsman S, Eng C, Beckman KB, LeNoir MA, Rodriguez-Santana JR, Villar J, Laprise C, Borrell LN, Ziv E, Burchard EG, Pino-Yanes M. PMID: 37802634; PMCID: PMC10841414.
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2 Fields:
Translation:
HumansCells
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European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation. Nat Commun. 2023 10 04; 14(1):6172.
Budu-Aggrey A, Kilanowski A, Sobczyk MK, 23andMe Research Team, Shringarpure SS, Mitchell R, Reis K, Reigo A, Estonian Biobank Research Team, Mägi R, Nelis M, Tanaka N, Brumpton BM, Thomas LF, Sole-Navais P, Flatley C, Espuela-Ortiz A, Herrera-Luis E, Lominchar JVT, Bork-Jensen J, Marenholz I, Arnau-Soler A, Jeong A, Fawcett KA, Baurecht H, Rodriguez E, Alves AC, Kumar A, Sleiman PM, Chang X, Medina-Gomez C, Hu C, Xu CJ, Qi C, El-Heis S, Titcombe P, Antoun E, Fadista J, Wang CA, Thiering E, Wu B, Kress S, Kothalawala DM, Kadalayil L, Duan J, Zhang H, Hadebe S, Hoffmann T, Jorgenson E, Choquet H, Risch N, Njølstad P, Andreassen OA, Johansson S, Almqvist C, Gong T, Ullemar V, Karlsson R, Magnusson PKE, Szwajda A, Burchard EG, Thyssen JP, Hansen T, Kårhus LL, Dantoft TM, Jeanrenaud ACSN, Ghauri A, Arnold A, Homuth G, Lau S, Nöthen MM, Hübner N, Imboden M, Visconti A, Falchi M, Bataille V, Hysi P, Ballardini N, Boomsma DI, Hottenga JJ, Müller-Nurasyid M, Ahluwalia TS, Stokholm J, Chawes B, Schoos AM, Esplugues A, Bustamante M, Raby B, Arshad S, German C, Esko T, Milani LA, Metspalu A, Terao C, Abuabara K, Løset M, Hveem K, Jacobsson B, Pino-Yanes M, Strachan DP, Grarup N, Linneberg A, Lee YA, Probst-Hensch N, Weidinger S, Jarvelin MR, Melén E, Hakonarson H, Irvine AD, Jarvis D, Nijsten T, Duijts L, Vonk JM, Koppelmann GH, Godfrey KM, Barton SJ, Feenstra B, Pennell CE, Sly PD, Holt PG, Williams LK, Bisgaard H, Bønnelykke K, Curtin J, Simpson A, Murray C, Schikowski T, Bunyavanich S, Weiss ST, Holloway JW, Min JL, Brown SJ, Standl M, Paternoster L. PMID: 37794016; PMCID: PMC10550990.
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17 Fields:
Translation:
Humans
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Epigenomic response to albuterol treatment in asthma-relevant airway epithelial cells. Clin Epigenetics. 2023 10 03; 15(1):156.
Perez-Garcia J, Pino-Yanes M, Plender EG, Everman JL, Eng C, Jackson ND, Moore CM, Beckman KB, Medina V, Sharma S, Winnica DE, Holguin F, Rodríguez-Santana J, Villar J, Ziv E, Seibold MA, Burchard EG. PMID: 37784136; PMCID: PMC10546710.
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1 Fields:
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HumansCells
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Race/Ethnicity and Clinical Prediction Algorithms for Childhood Asthma. NEJM Evid. 2023 Oct; 2(10):EVIDe2300187.
Witonsky J, Burchard EG. PMID: 38320186.
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Humans
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WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE. medRxiv. 2023 Aug 22.
Zhang X, Brody JA, Graff M, Highland HM, Chami N, Xu H, Wang Z, Ferrier K, Chittoor G, Josyula NS, Li X, Li Z, Allison MA, Becker DM, Bielak LF, Bis JC, Boorgula MP, Bowden DW, Broome JG, Buth EJ, Carlson CS, Chang KM, Chavan S, Chiu YF, Chuang LM, Conomos MP, DeMeo DL, Du M, Duggirala R, Eng C, Fohner AE, Freedman BI, Garrett ME, Guo X, Haiman C, Heavner BD, Hidalgo B, Hixson JE, Ho YL, Hobbs BD, Hu D, Hui Q, Hwu CM, Jackson RD, Jain D, Kalyani RR, Kardia SLR, Kelly TN, Lange EM, LeNoir M, Li C, Marchand LL, McDonald MN, McHugh CP, Morrison AC, Naseri T, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, O'Connell J, O'Donnell CJ, Palmer ND, Pankow JS, Perry JA, Peters U, Preuss MH, Rao DC, Regan EA, Reupena SM, Roden DM, Rodriguez-Santana J, Sitlani CM, Smith JA, Tiwari HK, Vasan RS, Wang Z, Weeks DE, Wessel J, Wiggins KL, Wilkens LR, Wilson PWF, Yanek LR, Yoneda ZT, Zhao W, Zöllner S, Arnett DK, Ashley-Koch AE, Barnes KC, Blangero J, Boerwinkle E, Burchard EG, Carson AP, Chasman DI, Chen YI, Curran JE, Fornage M, Gordeuk VR, He J, Heckbert SR, Hou L, Irvin MR, Kooperberg C, Minster RL, Mitchell BD, Nouraie M, Psaty BM, Raffield LM, Reiner AP, Rich SS, Rotter JI, Shoemaker MB, Smith NL, Taylor KD, Telen MJ, Weiss ST, Zhang Y, Heard-Costa N, Sun YV, Lin X, Adrienne Cupples L, Lange LA, Liu CT, Loos RJF, North KE, Justice AE. PMID: 37662265; PMCID: PMC10473809.
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Human genetics influences microbiome composition involved in asthma exacerbations despite inhaled corticosteroid treatment. J Allergy Clin Immunol. 2023 09; 152(3):799-806.e6.
Perez-Garcia J, Espuela-Ortiz A, Hernández-Pérez JM, González-Pérez R, Poza-Guedes P, Martin-Gonzalez E, Eng C, Sardón-Prado O, Mederos-Luis E, Corcuera-Elosegui P, Sánchez-Machín I, Korta-Murua J, Villar J, Burchard EG, Lorenzo-Diaz F, Pino-Yanes M. PMID: 37301411; PMCID: PMC10522330.
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1 Fields:
Translation:
Humans
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Gene expression in African Americans, Puerto Ricans and Mexican Americans reveals ancestry-specific patterns of genetic architecture. Nat Genet. 2023 06; 55(6):952-963.
Kachuri L, Mak ACY, Hu D, Eng C, Huntsman S, Elhawary JR, Gupta N, Gabriel S, Xiao S, Keys KL, Oni-Orisan A, Rodríguez-Santana JR, LeNoir MA, Borrell LN, Zaitlen NA, Williams LK, Gignoux CR, Burchard EG, Ziv E. PMID: 37231098; PMCID: PMC10260401.
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23 Fields:
Translation:
HumansCells
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Multi-omic approach associates blood methylome with bronchodilator drug response in pediatric asthma. J Allergy Clin Immunol. 2023 06; 151(6):1503-1512.
Perez-Garcia J, Herrera-Luis E, Li A, Mak ACY, Huntsman S, Oh SS, Elhawary JR, Eng C, Beckman KB, Hu D, Lorenzo-Diaz F, Lenoir MA, Rodriguez-Santana J, Zaitlen N, Villar J, Borrell LN, Burchard EG, Pino-Yanes M. PMID: 36796456.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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PubMed Mentions:
1
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Ancestral risk modification for multiple sclerosis susceptibility detected across the Major Histocompatibility Complex in a multi-ethnic population. PLoS One. 2022; 17(12):e0279132.
Beecham AH, Amezcua L, Chinea A, Manrique CP, Gomez L, Martinez A, Beecham GW, Patsopoulos NA, Chitnis T, Weiner HL, De Jager PL, Burchard EG, Lund BT, Fitzgerald KC, Calabresi PA, Delgado SR, Oksenberg JR, McCauley JL. PMID: 36548255; PMCID: PMC9778564.
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6 Fields:
Translation:
Humans
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Differences in Self-Reported Food Allergy and Food-Associated Anaphylaxis by Race and Ethnicity Among SAPPHIRE Cohort Participants. J Allergy Clin Immunol Pract. 2023 04; 11(4):1123-1133.e11.
Xiao S, Sahasrabudhe N, Yang M, Hu D, Sleiman P, Hochstadt S, Cabral W, Gilliland F, Gauderman WJ, Martinez F, Hakonarson H, Kumar R, Burchard EG, Williams LK. PMID: 36403896; PMCID: PMC10085828.
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1 Fields:
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Humans
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Author Correction: Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology. Nat Commun. 2022 Oct 03; 13(1):5806.
Sajuthi SP, Everman JL, Jackson ND, Saef B, Rios CL, Moore CM, Mak ACY, Eng C, Fairbanks-Mahnke A, Salazar S, Elhawary J, Huntsman S, Medina V, Nickerson DA, Germer S, Zody MC, Abecasis G, Kang HM, Rice KM, Kumar R, Zaitlen NA, Oh S, NHLBI Trans–Omics for Precision Medicine (TOPMed) Consortium, Rodríguez-Santana J, Burchard EG, Seibold MA. PMID: 36192399; PMCID: PMC9530212.
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Admixture mapping of severe asthma exacerbations in Hispanic/Latino children and youth. Thorax. 2023 03; 78(3):233-241.
Herrera-Luis E, Mak ACY, Perez-Garcia J, Martin-Gonzalez E, Eng C, Beckman KB, Huntsman S, Hu D, González-Pérez R, Hernández-Pérez JM, Mederos-Luis E, Sio YY, Poza-Guedes P, Sardón O, Corcuera P, Sánchez-Machín I, Korta-Murua J, Martínez-Rivera C, Mullol J, Muñoz X, Valero A, Sastre J, Garcia-Aymerich J, Llop S, Torrent M, Casas M, Rodríguez-Santana JR, Villar J, Del Pozo V, Lorenzo-Diaz F, Williams LK, Melén E, Chew FT, Borrell LN, Burchard EG, Pino-Yanes M. PMID: 36180068; PMCID: PMC9957797.
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8 Fields:
Translation:
Humans
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Association of bronchial steroid inducible methylation quantitative trait loci with asthma and chronic obstructive pulmonary disease treatment response. Clin Transl Allergy. 2022 Aug; 12(8):e12173.
Slob EMA, Faiz A, van Nijnatten J, Vijverberg SJH, Longo C, Kutlu M, Chew FT, Sio YY, Herrera-Luis E, Espuela-Ortiz A, Perez-Garcia J, Pino-Yanes M, Burchard EG, Potocnik U, Gorenjak M, Palmer C, Maroteau C, Turner S, Verhamme K, Karimi L, Mukhopadhyay S, Timens W, Hiemstra PS, Pijnenburg MW, Neighbors M, Grimbaldeston MA, Tew GW, Brandsma CA, Berce V, Aliee H, Theis F, Sin DD, Li X, van den Berge M, Maitland-van der Zee AH, Koppelman GH. PMID: 36036237; PMCID: PMC9421427.
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Genome-wide association study in minority children with asthma implicates DNAH5 in bronchodilator responsiveness. Sci Rep. 2022 07 22; 12(1):12514.
Joo J, Mak ACY, Xiao S, Sleiman PM, Hu D, Huntsman S, Eng C, Kan M, Diwakar AR, Lasky-Su JA, Weiss ST, Sordillo JE, Wu AC, Cloutier M, Canino G, Forno E, Celedón JC, Seibold MA, Hakonarson H, Williams LK, Burchard EG, Himes BE. PMID: 35869121; PMCID: PMC9307508.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Multi-ancestry genome-wide association study of asthma exacerbations. Pediatr Allergy Immunol. 2022 06; 33(6):e13802.
Herrera-Luis E, Ortega VE, Ampleford EJ, Sio YY, Granell R, de Roos E, Terzikhan N, Vergara EE, Hernandez-Pacheco N, Perez-Garcia J, Martin-Gonzalez E, Lorenzo-Diaz F, Hashimoto S, Brinkman P, U-BIOPRED Study Group, Jorgensen AL, Yan Q, Forno E, Vijverberg SJ, Lethem R, Espuela-Ortiz A, Gorenjak M, Eng C, González-Pérez R, Hernández-Pérez JM, Poza-Guedes P, Sardón O, Corcuera P, Hawkins GA, Marsico A, Bahmer T, Rabe KF, Hansen G, Kopp MV, Rios R, Cruz MJ, González-Barcala FJ, Olaguibel JM, Plaza V, Quirce S, Canino G, Cloutier M, Del Pozo V, Rodriguez-Santana JR, Korta-Murua J, Villar J, Potocnik U, Figueiredo C, Kabesch M, Mukhopadhyay S, Pirmohamed M, Hawcutt DB, Melén E, Palmer CN, Turner S, Maitland-van der Zee AH, von Mutius E, Celedón JC, Brusselle G, Chew FT, Bleecker E, Meyers D, Burchard EG, Pino-Yanes M. PMID: 35754128; PMCID: PMC9671132.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Clotting factor genes are associated with preeclampsia in high-altitude pregnant women in the Peruvian Andes. Am J Hum Genet. 2022 06 02; 109(6):1117-1139.
Nieves-Colón MA, Badillo Rivera KM, Sandoval K, Villanueva Dávalos V, Enriquez Lencinas LE, Mendoza-Revilla J, Adhikari K, González-Buenfil R, Chen JW, Zhang ET, Sockell A, Ortiz-Tello P, Hurtado GM, Condori Salas R, Cebrecos R, Manzaneda Choque JC, Manzaneda Choque FP, Yábar Pilco GP, Rawls E, Eng C, Huntsman S, Burchard E, Ruiz-Linares A, González-José R, Bedoya G, Rothhammer F, Bortolini MC, Poletti G, Gallo C, Bustamante CD, Baker JC, Gignoux CR, Wojcik GL, Moreno-Estrada A. PMID: 35588731; PMCID: PMC9247825.
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6 Fields:
Translation:
Humans
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Methylation risk scores for childhood aeroallergen sensitization: Results from the LISA birth cohort. Allergy. 2022 09; 77(9):2803-2817.
Kilanowski A, Chen J, Everson T, Thiering E, Wilson R, Gladish N, Waldenberger M, Zhang H, Celedón JC, Burchard EG, Peters A, Standl M, Hüls A. PMID: 35437756; PMCID: PMC9437118.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology. Nat Commun. 2022 03 28; 13(1):1632.
Sajuthi SP, Everman JL, Jackson ND, Saef B, Rios CL, Moore CM, Mak ACY, Eng C, Fairbanks-Mahnke A, Salazar S, Elhawary J, Huntsman S, Medina V, Nickerson DA, Germer S, Zody MC, Abecasis G, Kang HM, Rice KM, Kumar R, Zaitlen NA, Oh S, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Rodríguez-Santana J, Burchard EG, Seibold MA. PMID: 35347136; PMCID: PMC8960819.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Genetic Ancestry to Improve Precision of Race/Ethnicity-based Lung Function Equations in Children. Am J Respir Crit Care Med. 2022 03 15; 205(6):725-727.
Witonsky J, Elhawary JR, Eng C, Rodríguez-Santana JR, Borrell LN, Burchard EG. PMID: 35085059.
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7 Fields:
Translation:
Humans
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Epigenome-wide association study of lung function in Latino children and youth with asthma. Clin Epigenetics. 2022 01 15; 14(1):9.
Herrera-Luis E, Li A, Mak ACY, Perez-Garcia J, Elhawary JR, Oh SS, Hu D, Eng C, Keys KL, Huntsman S, Beckman KB, Borrell LN, Rodriguez-Santana J, Burchard EG, Pino-Yanes M. PMID: 35033200; PMCID: PMC8760660.
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9 Fields:
Translation:
HumansCells
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Race- and Ethnicity-Based Spirometry Reference Equations: Are They Accurate for Genetically Admixed Children? Chest. 2022 07; 162(1):184-195.
Witonsky J, Elhawary JR, Eng C, Rodríguez-Santana JR, Borrell LN, Burchard EG. PMID: 35033507; PMCID: PMC9279648.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Multiomics analysis identifies BIRC3 as a novel glucocorticoid response-associated gene. J Allergy Clin Immunol. 2022 06; 149(6):1981-1991.
Kan M, Diwadkar AR, Shuai H, Joo J, Wang AL, Ong MS, Sordillo JE, Iribarren C, Lu MX, Hernandez-Pacheco N, Perez-Garcia J, Gorenjak M, Potocnik U, Burchard EG, Pino-Yanes M, Wu AC, Himes BE. PMID: 34971648; PMCID: PMC9177524.
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4 Fields:
Translation:
Humans
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Disentangling the impact of alcohol use and hepatitis C on insulin action in Latino individuals. Alcohol Clin Exp Res. 2022 01; 46(1):87-99.
Kim RG, Kramer-Feldman J, Bacchetti P, Grimes B, Burchard E, Eng C, Hu D, Hellerstein M, Khalili M. PMID: 34773280; PMCID: PMC8799492.
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Humans
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Pharmacogenetic studies of long-acting beta agonist and inhaled corticosteroid responsiveness in randomised controlled trials of individuals of African descent with asthma. Lancet Child Adolesc Health. 2021 12; 5(12):862-872.
Ortega VE, Daya M, Szefler SJ, Bleecker ER, Chinchilli VM, Phipatanakul W, Mauger D, Martinez FD, Herrera-Luis E, Pino-Yanes M, Hawkins GA, Ampleford EJ, Kunselman SJ, Cox C, Bacharier LB, Cabana MD, Cardet JC, Castro M, Denlinger LC, Eng C, Fitzpatrick AM, Holguin F, Hu D, Jackson DJ, Jarjour N, Kraft M, Krishnan JA, Lazarus SC, Lemanske RF, Lima JJ, Lugogo N, Mak A, Moore WC, Naureckas ET, Peters SP, Pongracic JA, Sajuthi SP, Seibold MA, Smith LJ, Solway J, Sorkness CA, Wenzel S, White SR, Burchard EG, Barnes K, Meyers DA, Israel E, Wechsler ME, NHLBI AsthmaNet. PMID: 34762840; PMCID: PMC8787857.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Role of Sex on the Genetic Susceptibility to Childhood Asthma in Latinos and African Americans. J Pers Med. 2021 Nov 03; 11(11).
Espuela-Ortiz A, Herrera-Luis E, Lorenzo-Díaz F, Hu D, Eng C, Villar J, Rodriguez-Santana JR, Burchard EG, Pino-Yanes M. PMID: 34834492; PMCID: PMC8625344.
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PubMed Mentions:
5
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Lymph node-resident dendritic cells drive TH2 cell development involving MARCH1. Sci Immunol. 2021 Oct 15; 6(64):eabh0707.
Castellanos CA, Ren X, Gonzalez SL, Li HK, Schroeder AW, Liang HE, Laidlaw BJ, Hu D, Mak ACY, Eng C, Rodríguez-Santana JR, LeNoir M, Yan Q, Celedón JC, Burchard EG, Zamvil SS, Ishido S, Locksley RM, Cyster JG, Huang X, Shin JS. PMID: 34652961; PMCID: PMC8736284.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Paths and timings of the peopling of Polynesia inferred from genomic networks. Nature. 2021 09; 597(7877):522-526.
Ioannidis AG, Blanco-Portillo J, Sandoval K, Hagelberg E, Barberena-Jonas C, Hill AVS, Rodríguez-Rodríguez JE, Fox K, Robson K, Haoa-Cardinali S, Quinto-Cortés CD, Miquel-Poblete JF, Auckland K, Parks T, Sofro ASM, Ávila-Arcos MC, Sockell A, Homburger JR, Eng C, Huntsman S, Burchard EG, Gignoux CR, Verdugo RA, Moraga M, Bustamante CD, Mentzer AJ, Moreno-Estrada A. PMID: 34552258; PMCID: PMC9710236.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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LTA4H rs2660845 association with montelukast response in early and late-onset asthma. PLoS One. 2021; 16(9):e0257396.
Maroteau C, Espuela-Ortiz A, Herrera-Luis E, Srinivasan S, Carr F, Tavendale R, Wilson K, Hernandez-Pacheco N, Chalmers JD, Turner S, Mukhopadhyay S, Maitland-van der Zee AH, Burchard EG, Pino-Yanes M, Young S, Lassi G, Platt A, Palmer CNA, PiCA Consortium. PMID: 34550981; PMCID: PMC8457475.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
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Racial/ethnic differences in eligibility for asthma biologics among pediatric populations. J Allergy Clin Immunol. 2021 11; 148(5):1324-1331.e12.
Wohlford EM, Huang PF, Elhawary JR, Millette LA, Contreras MG, Witonsky J, Holweg CTJ, Oh SS, Lee C, Merenda C, Rabin RL, Araojo R, Mak ACY, Eng CS, Hu D, Huntsman S, LeNoir MA, Rodríguez-Santana JR, Borrell LN, Burchard EG. PMID: 34536416; PMCID: PMC9211042.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
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Population sequencing data reveal a compendium of mutational processes in the human germ line. Science. 2021 Aug 27; 373(6558):1030-1035.
Seplyarskiy VB, Soldatov RA, Koch E, McGinty RJ, Goldmann JM, Hernandez RD, Barnes K, Correa A, Burchard EG, Ellinor PT, McGarvey ST, Mitchell BD, Vasan RS, Redline S, Silverman E, Weiss ST, Arnett DK, Blangero J, Boerwinkle E, He J, Montgomery C, Rao DC, Rotter JI, Taylor KD, Brody JA, Chen YI, de las Fuentes L, Hwu CM, Rich SS, Manichaikul AW, Mychaleckyj JC, Palmer ND, Smith JA, Kardia SLR, Peyser PA, Bielak LF, O'Connor TD, Emery LS, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Population Genetics Working Group, Gilissen C, Wong WSW, Kharchenko PV, Sunyaev S. PMID: 34385354; PMCID: PMC9217108.
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PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Identification of ROBO2 as a Potential Locus Associated with Inhaled Corticosteroid Response in Childhood Asthma. J Pers Med. 2021 Jul 28; 11(8).
Hernandez-Pacheco N, Gorenjak M, Li J, Repnik K, Vijverberg SJ, Berce V, Jorgensen A, Karimi L, Schieck M, Samedy-Bates LA, Tavendale R, Villar J, Mukhopadhyay S, Pirmohamed M, Verhamme KMC, Kabesch M, Hawcutt DB, Turner S, Palmer CN, Tantisira KG, Burchard EG, Maitland-van der Zee AH, Flores C, Potocnik U, Pino-Yanes M. PMID: 34442380; PMCID: PMC8399629.
View in:
PubMed Mentions:
6
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ADRB2 haplotypes and asthma exacerbations in children and young adults: An individual participant data meta-analysis. Clin Exp Allergy. 2021 09; 51(9):1157-1171.
Karimi L, Vijverberg SJ, Engelkes M, Hernandez-Pacheco N, Farzan N, Soares P, Pino-Yanes M, Jorgensen AL, Eng C, Mukhopadhyay S, Schieck M, Kabesch M, Burchard EG, Chew FT, Sio YY, Potocnik U, Gorenjak M, Hawcutt DB, Palmer CN, Turner S, Janssens HM, Maitland-van der Zee AH, Verhamme KMC, PiCA and SysPharmPedia consortia. PMID: 34128573; PMCID: PMC8503671.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Office of Management and Budget Racial/Ethnic Categories in Mortality Research: A Framework for Including the Voices of Racialized Communities. Am J Public Health. 2021 07; 111(S2):S133-S140.
Hayes-Bautista DE, Bryant M, Yudell M, Hayes-Bautista TM, Partlow K, Popejoy AB, Burchard E, Hsu P. PMID: 34314200; PMCID: PMC8495649.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
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Robust, flexible, and scalable tests for Hardy-Weinberg equilibrium across diverse ancestries. Genetics. 2021 05 17; 218(1).
Kwong AM, Blackwell TW, LeFaive J, de Andrade M, Barnard J, Barnes KC, Blangero J, Boerwinkle E, Burchard EG, Cade BE, Chasman DI, Chen H, Conomos MP, Cupples LA, Ellinor PT, Eng C, Gao Y, Guo X, Irvin MR, Kelly TN, Kim W, Kooperberg C, Lubitz SA, Mak ACY, Manichaikul AW, Mathias RA, Montasser ME, Montgomery CG, Musani S, Palmer ND, Peloso GM, Qiao D, Reiner AP, Roden DM, Shoemaker MB, Smith JA, Smith NL, Su JL, Tiwari HK, Weeks DE, Weiss ST, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Analysis Working Group, Scott LJ, Smith AV, Abecasis GR, Boehnke M, Kang HM. PMID: 33720349; PMCID: PMC8128395.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Genome-wide association study of asthma exacerbations despite inhaled corticosteroid use. Eur Respir J. 2021 05; 57(5).
Hernandez-Pacheco N, Vijverberg SJ, Herrera-Luis E, Li J, Sio YY, Granell R, Corrales A, Maroteau C, Lethem R, Perez-Garcia J, Farzan N, Repnik K, Gorenjak M, Soares P, Karimi L, Schieck M, Pérez-Méndez L, Berce V, Tavendale R, Eng C, Sardon O, Kull I, Mukhopadhyay S, Pirmohamed M, Verhamme KMC, Burchard EG, Kabesch M, Hawcutt DB, Melén E, Potocnik U, Chew FT, Tantisira KG, Turner S, Palmer CN, Flores C, Pino-Yanes M, Maitland-van der Zee AH, PiCA and SysPharmPedia consortia. PMID: 33303529; PMCID: PMC8122045.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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A genome-wide association study of severe asthma exacerbations in Latino children and adolescents. Eur Respir J. 2021 04; 57(4).
Yan Q, Forno E, Herrera-Luis E, Pino-Yanes M, Qi C, Rios R, Han YY, Kim S, Oh S, Acosta-Pérez E, Zhang R, Hu D, Eng C, Huntsman S, Avila L, Boutaoui N, Cloutier MM, Soto-Quiros ME, Xu CJ, Weiss ST, Lasky-Su J, Kiedrowski MR, Figueiredo C, Bomberger J, Barreto ML, Canino G, Chen W, Koppelman GH, Burchard EG, Celedón JC. PMID: 33093117; PMCID: PMC8026735.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Genome-wide association studies of exacerbations in children using long-acting beta2-agonists. Pediatr Allergy Immunol. 2021 08; 32(6):1197-1207.
Slob EMA, Richards LB, Vijverberg SJH, Longo C, Koppelman GH, Pijnenburg MWH, Bel EHD, Neerincx AH, Herrera Luis E, Perez-Garcia J, Tim Chew F, Yie Sio Y, Andiappan AK, Turner SW, Mukhopadhyay S, Palmer CNA, Hawcutt D, Jorgensen AL, Burchard EG, Hernandez-Pacheco N, Pino-Yanes M, Maitland-van der Zee AH. PMID: 33706416; PMCID: PMC8328929.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. 2021 Mar; 591(7851):E27.
Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Niroula A, Lin AE, Taub MA, Aguet F, Ardlie K, Mitchell BD, Barnes KC, Moscati A, Fornage M, Redline S, Psaty BM, Silverman EK, Weiss ST, Palmer ND, Vasan RS, Burchard EG, Kardia SLR, He J, Kaplan RC, Smith NL, Arnett DK, Schwartz DA, Correa A, de Andrade M, Guo X, Konkle BA, Custer B, Peralta JM, Gui H, Meyers DA, McGarvey ST, Chen IY, Shoemaker MB, Peyser PA, Broome JG, Gogarten SM, Wang FF, Wong Q, Montasser ME, Daya M, Kenny EE, North KE, Launer LJ, Cade BE, Bis JC, Cho MH, Lasky-Su J, Bowden DW, Cupples LA, Mak ACY, Becker LC, Smith JA, Kelly TN, Aslibekyan S, Heckbert SR, Tiwari HK, Yang IV, Heit JA, Lubitz SA, Johnsen JM, Curran JE, Wenzel SE, Weeks DE, Rao DC, Darbar D, Moon JY, Tracy RP, Buth EJ, Rafaels N, Loos RJF, Durda P, Liu Y, Hou L, Lee J, Kachroo P, Freedman BI, Levy D, Bielak LF, Hixson JE, Floyd JS, Whitsel EA, Ellinor PT, Irvin MR, Fingerlin TE, Raffield LM, Armasu SM, Wheeler MM, Sabino EC, Blangero J, Williams LK, Levy BD, Sheu WH, Roden DM, Boerwinkle E, Manson JE, Mathias RA, Desai P, Taylor KD, Johnson AD, NHLBI Trans-Omics for Precision Medicine Consortium, Auer PL, Kooperberg C, Laurie CC, Blackwell TW, Smith AV, Zhao H, Lange E, Lange L, Rich SS, Rotter JI, Wilson JG, Scheet P, Kitzman JO, Lander ES, Engreitz JM, Ebert BL, Reiner AP, Jaiswal S, Abecasis G, Sankaran VG, Kathiresan S, Natarajan P. PMID: 33707633.
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PubMed Mentions:
2 Fields:
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Mapping the 17q12-21.1 Locus for Variants Associated with Early-Onset Asthma in African Americans. Am J Respir Crit Care Med. 2021 02 15; 203(4):424-436.
Gui H, Levin AM, Hu D, Sleiman P, Xiao S, Mak ACY, Yang M, Barczak AJ, Huntsman S, Eng C, Hochstadt S, Zhang E, Whitehouse K, Simons S, Cabral W, Takriti S, Abecasis G, Blackwell TW, Kang HM, Nickerson DA, Germer S, Lanfear DE, Gilliland F, Gauderman WJ, Kumar R, Erle DJ, Martinez FD, Hakonarson H, Burchard EG, Williams LK. PMID: 32966749; PMCID: PMC7885840.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. Nature. 2021 Feb; 590(7845):290-299.
Taliun D, Harris DN, Kessler MD, Carlson J, Szpiech ZA, Torres R, Taliun SAG, Corvelo A, Gogarten SM, Kang HM, Pitsillides AN, LeFaive J, Lee SB, Tian X, Browning BL, Das S, Emde AK, Clarke WE, Loesch DP, Shetty AC, Blackwell TW, Smith AV, Wong Q, Liu X, Conomos MP, Bobo DM, Aguet F, Albert C, Alonso A, Ardlie KG, Arking DE, Aslibekyan S, Auer PL, Barnard J, Barr RG, Barwick L, Becker LC, Beer RL, Benjamin EJ, Bielak LF, Blangero J, Boehnke M, Bowden DW, Brody JA, Burchard EG, Cade BE, Casella JF, Chalazan B, Chasman DI, Chen YI, Cho MH, Choi SH, Chung MK, Clish CB, Correa A, Curran JE, Custer B, Darbar D, Daya M, de Andrade M, DeMeo DL, Dutcher SK, Ellinor PT, Emery LS, Eng C, Fatkin D, Fingerlin T, Forer L, Fornage M, Franceschini N, Fuchsberger C, Fullerton SM, Germer S, Gladwin MT, Gottlieb DJ, Guo X, Hall ME, He J, Heard-Costa NL, Heckbert SR, Irvin MR, Johnsen JM, Johnson AD, Kaplan R, Kardia SLR, Kelly T, Kelly S, Kenny EE, Kiel DP, Klemmer R, Konkle BA, Kooperberg C, Köttgen A, Lange LA, Lasky-Su J, Levy D, Lin X, Lin KH, Liu C, Loos RJF, Garman L, Gerszten R, Lubitz SA, Lunetta KL, Mak ACY, Manichaikul A, Manning AK, Mathias RA, McManus DD, McGarvey ST, Meigs JB, Meyers DA, Mikulla JL, Minear MA, Mitchell BD, Mohanty S, Montasser ME, Montgomery C, Morrison AC, Murabito JM, Natale A, Natarajan P, Nelson SC, North KE, O'Connell JR, Palmer ND, Pankratz N, Peloso GM, Peyser PA, Pleiness J, Post WS, Psaty BM, Rao DC, Redline S, Reiner AP, Roden D, Rotter JI, Ruczinski I, Sarnowski C, Schoenherr S, Schwartz DA, Seo JS, Seshadri S, Sheehan VA, Sheu WH, Shoemaker MB, Smith NL, Smith JA, Sotoodehnia N, Stilp AM, Tang W, Taylor KD, Telen M, Thornton TA, Tracy RP, Van Den Berg DJ, Vasan RS, Viaud-Martinez KA, Vrieze S, Weeks DE, Weir BS, Weiss ST, Weng LC, Willer CJ, Zhang Y, Zhao X, Arnett DK, Ashley-Koch AE, Barnes KC, Boerwinkle E, Gabriel S, Gibbs R, Rice KM, Rich SS, Silverman EK, Qasba P, Gan W, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Papanicolaou GJ, Nickerson DA, Browning SR, Zody MC, Zöllner S, Wilson JG, Cupples LA, Laurie CC, Jaquish CE, Hernandez RD, O'Connor TD, Abecasis GR. PMID: 33568819; PMCID: PMC7875770.
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PubMed Mentions:
897 Fields:
Translation:
Humans
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Native American Ancestry and Air Pollution Interact to Impact Bronchodilator Response in Puerto Rican Children with Asthma. Ethn Dis. 2021; 31(1):77-88.
Contreras MG, Keys K, Magaña J, Goddard PC, Risse-Adams O, Zeiger AM, Mak ACY, Samedy-Bates LA, Neophytou AM, Lee E, Thakur N, Elhawary JR, Hu D, Huntsman S, Eng C, Hu T, Burchard EG, White MJ. PMID: 33519158; PMCID: PMC7843041.
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PubMed Mentions:
3 Fields:
Translation:
HumansPHPublic Health
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Race and Genetic Ancestry in Medicine - A Time for Reckoning with Racism. N Engl J Med. 2021 Feb 04; 384(5):474-480.
Borrell LN, Elhawary JR, Fuentes-Afflick E, Witonsky J, Bhakta N, Wu AHB, Bibbins-Domingo K, Rodríguez-Santana JR, Lenoir MA, Gavin JR, Kittles RA, Zaitlen NA, Wilkes DS, Powe NR, Ziv E, Burchard EG. PMID: 33406325; PMCID: PMC8979367.
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PubMed Mentions:
260 Fields:
Translation:
Humans
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NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity. J Allergy Clin Immunol. 2021 06; 147(6):2134-2145.e20.
Moecking J, Laohamonthonkul P, Chalker K, White MJ, Harapas CR, Yu CH, Davidson S, Hrovat-Schaale K, Hu D, Eng C, Huntsman S, Calleja DJ, Horvat JC, Hansbro PM, O'Donoghue RJJ, Ting JP, Burchard EG, Geyer M, Gerlic M, Masters SL. PMID: 33378691; PMCID: PMC8168955.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Asthma and its relationship to mitochondrial copy number: Results from the Asthma Translational Genomics Collaborative (ATGC) of the Trans-Omics for Precision Medicine (TOPMed) program. PLoS One. 2020; 15(11):e0242364.
Cocco MP, White E, Xiao S, Hu D, Mak A, Sleiman P, Yang M, Bobbitt KR, Gui H, Levin AM, Hochstadt S, Whitehouse K, Rynkowski D, Barczak AJ, Abecasis G, Blackwell TW, Kang HM, Nickerson DA, Germer S, Ding J, Lanfear DE, Gilliland F, Gauderman WJ, Kumar R, Erle DJ, Martinez F, Hakonarson H, Burchard EG, Williams LK. PMID: 33237978; PMCID: PMC7688161.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. 2020 10; 586(7831):763-768.
Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Lin AE, Taub MA, Aguet F, Ardlie K, Mitchell BD, Barnes KC, Moscati A, Fornage M, Redline S, Psaty BM, Silverman EK, Weiss ST, Palmer ND, Vasan RS, Burchard EG, Kardia SLR, He J, Kaplan RC, Smith NL, Arnett DK, Schwartz DA, Correa A, de Andrade M, Guo X, Konkle BA, Custer B, Peralta JM, Gui H, Meyers DA, McGarvey ST, Chen IY, Shoemaker MB, Peyser PA, Broome JG, Gogarten SM, Wang FF, Wong Q, Montasser ME, Daya M, Kenny EE, North KE, Launer LJ, Cade BE, Bis JC, Cho MH, Lasky-Su J, Bowden DW, Cupples LA, Mak ACY, Becker LC, Smith JA, Kelly TN, Aslibekyan S, Heckbert SR, Tiwari HK, Yang IV, Heit JA, Lubitz SA, Johnsen JM, Curran JE, Wenzel SE, Weeks DE, Rao DC, Darbar D, Moon JY, Tracy RP, Buth EJ, Rafaels N, Loos RJF, Durda P, Liu Y, Hou L, Lee J, Kachroo P, Freedman BI, Levy D, Bielak LF, Hixson JE, Floyd JS, Whitsel EA, Ellinor PT, Irvin MR, Fingerlin TE, Raffield LM, Armasu SM, Wheeler MM, Sabino EC, Blangero J, Williams LK, Levy BD, Sheu WH, Roden DM, Boerwinkle E, Manson JE, Mathias RA, Desai P, Taylor KD, Johnson AD, NHLBI Trans-Omics for Precision Medicine Consortium, Auer PL, Kooperberg C, Laurie CC, Blackwell TW, Smith AV, Zhao H, Lange E, Lange L, Rich SS, Rotter JI, Wilson JG, Scheet P, Kitzman JO, Lander ES, Engreitz JM, Ebert BL, Reiner AP, Jaiswal S, Abecasis G, Sankaran VG, Kathiresan S, Natarajan P. PMID: 33057201; PMCID: PMC7944936.
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PubMed Mentions:
274 Fields:
Translation:
HumansCells
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Type 2 and interferon inflammation regulate SARS-CoV-2 entry factor expression in the airway epithelium. Nat Commun. 2020 10 12; 11(1):5139.
Sajuthi SP, DeFord P, Li Y, Jackson ND, Montgomery MT, Everman JL, Rios CL, Pruesse E, Nolin JD, Plender EG, Wechsler ME, Mak ACY, Eng C, Salazar S, Medina V, Wohlford EM, Huntsman S, Nickerson DA, Germer S, Zody MC, Abecasis G, Kang HM, Rice KM, Kumar R, Oh S, Rodriguez-Santana J, Burchard EG, Seibold MA. PMID: 33046696; PMCID: PMC7550582.
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PubMed Mentions:
121 Fields:
Translation:
HumansCellsPHPublic Health
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A deoxyribonuclease 1-like 3 genetic variant associates with asthma exacerbations. J Allergy Clin Immunol. 2021 03; 147(3):1095-1097.e10.
Herrera-Luis E, Lorenzo-Diaz F, Samedy-Bates LA, Eng C, Villar J, Rodriguez-Santana JR, Burchard EG, Pino-Yanes M. PMID: 33035569; PMCID: PMC7940549.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
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Whole-Genome Sequencing Identifies Novel Functional Loci Associated with Lung Function in Puerto Rican Youth. Am J Respir Crit Care Med. 2020 10 01; 202(7):962-972.
Lee EY, Mak ACY, Hu D, Sajuthi S, White MJ, Keys KL, Eckalbar W, Bonser L, Huntsman S, Urbanek C, Eng C, Jain D, Abecasis G, Kang HM, Germer S, Zody MC, Nickerson DA, Erle D, Ziv E, Rodriguez-Santana J, Seibold MA, Burchard EG. PMID: 32459537; PMCID: PMC7528787.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Integrative genomic analysis in African American children with asthma finds three novel loci associated with lung function. Genet Epidemiol. 2021 03; 45(2):190-208.
Goddard PC, Keys KL, Mak ACY, Lee EY, Liu AK, Samedy-Bates LA, Risse-Adams O, Contreras MG, Elhawary JR, Hu D, Huntsman S, Oh SS, Salazar S, Eng C, Himes BE, White MJ, Burchard EG. PMID: 32989782; PMCID: PMC7902343.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma. Allergy. 2021 04; 76(4):1238-1243.
Hernandez-Pacheco N, Gorenjak M, Jurgec S, Corrales A, Jorgensen A, Karimi L, Vijverberg SJ, Berce V, Schieck M, Acosta-Herrera M, Kerick M, Samedy-Bates LA, Tavendale R, Villar J, Mukhopadhyay S, Pirmohamed M, Verhamme KMC, Kabesch M, Hawcutt DB, Turner S, Palmer CN, Burchard EG, Maitland-van der Zee AH, Flores C, Potocnik U, Pino-Yanes M, PiCA and SysPharmPedia consortia. PMID: 32786158; PMCID: PMC7908891.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Genome-wide association study reveals a novel locus for asthma with severe exacerbations in diverse populations. Pediatr Allergy Immunol. 2021 01; 32(1):106-115.
Herrera-Luis E, Espuela-Ortiz A, Lorenzo-Diaz F, Keys KL, Mak ACY, Eng C, Huntsman S, Villar J, Rodriguez-Santana JR, Burchard EG, Pino-Yanes M. PMID: 32841424; PMCID: PMC7886969.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
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A genome-wide association study of asthma hospitalizations in adults. J Allergy Clin Immunol. 2021 03; 147(3):933-940.
Yan Q, Forno E, Herrera-Luis E, Pino-Yanes M, Yang G, Oh S, Acosta-Pérez E, Hu D, Eng C, Huntsman S, Rodriguez-Santana JR, Cloutier MM, Canino G, Burchard EG, Chen W, Celedón JC. PMID: 32890573; PMCID: PMC7921212.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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A genome-wide study of DNA methylation in white blood cells and asthma in Latino children and youth. Epigenetics. 2021 05; 16(5):577-585.
Jiang Y, Forno E, Han YY, Xu Z, Hu D, Boutaoui N, Eng C, Acosta-Pérez E, Huntsman S, Colón-Semidey A, Keys KL, Rodríguez-Santana JR, Alvarez M, Pino-Yanes M, Canino G, Chen W, Burchard EG, Celedón JC. PMID: 32799603; PMCID: PMC8078676.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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On the cross-population generalizability of gene expression prediction models. PLoS Genet. 2020 08; 16(8):e1008927.
Keys KL, Mak ACY, White MJ, Eckalbar WL, Dahl AW, Mefford J, Mikhaylova AV, Contreras MG, Elhawary JR, Eng C, Hu D, Huntsman S, Oh SS, Salazar S, Lenoir MA, Ye JC, Thornton TA, Zaitlen N, Burchard EG, Gignoux CR. PMID: 32797036; PMCID: PMC7449671.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Genome-Wide Analysis Reveals Mucociliary Remodeling of the Nasal Airway Epithelium Induced by Urban PM2.5. Am J Respir Cell Mol Biol. 2020 08; 63(2):172-184.
Montgomery MT, Sajuthi SP, Cho SH, Everman JL, Rios CL, Goldfarbmuren KC, Jackson ND, Saef B, Cromie M, Eng C, Medina V, Elhawary JR, Oh SS, Rodriguez-Santana J, Vladar EK, Burchard EG, Seibold MA. PMID: 32275839; PMCID: PMC7397762.
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PubMed Mentions:
19 Fields:
Translation:
HumansPHPublic Health
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Native American gene flow into Polynesia predating Easter Island settlement. Nature. 2020 07; 583(7817):572-577.
Ioannidis AG, Blanco-Portillo J, Sandoval K, Hagelberg E, Miquel-Poblete JF, Moreno-Mayar JV, Rodríguez-Rodríguez JE, Quinto-Cortés CD, Auckland K, Parks T, Robson K, Hill AVS, Avila-Arcos MC, Sockell A, Homburger JR, Wojcik GL, Barnes KC, Herrera L, Berríos S, Acuña M, Llop E, Eng C, Huntsman S, Burchard EG, Gignoux CR, Cifuentes L, Verdugo RA, Moraga M, Mentzer AJ, Bustamante CD, Moreno-Estrada A. PMID: 32641827; PMCID: PMC8939867.
View in:
PubMed Mentions:
29 Fields:
Translation:
Humans
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Single-Cell and Population Transcriptomics Reveal Pan-epithelial Remodeling in Type 2-High Asthma. Cell Rep. 2020 07 07; 32(1):107872.
Jackson ND, Everman JL, Chioccioli M, Feriani L, Goldfarbmuren KC, Sajuthi SP, Rios CL, Powell R, Armstrong M, Gomez J, Michel C, Eng C, Oh SS, Rodriguez-Santana J, Cicuta P, Reisdorph N, Burchard EG, Seibold MA. PMID: 32640237; PMCID: PMC8046336.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansCells
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An epistatic interaction between pre-natal smoke exposure and socioeconomic status has a significant impact on bronchodilator drug response in African American youth with asthma. BioData Min. 2020; 13:7.
Magaña J, Contreras MG, Keys KL, Risse-Adams O, Goddard PC, Zeiger AM, Mak ACY, Elhawary JR, Samedy-Bates LA, Lee E, Thakur N, Hu D, Eng C, Salazar S, Huntsman S, Hu T, Burchard EG, White MJ. PMID: 32636926; PMCID: PMC7333373.
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PubMed Mentions:
1
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Sequencing and imputation in GWAS: Cost-effective strategies to increase power and genomic coverage across diverse populations. Genet Epidemiol. 2020 09; 44(6):537-549.
Quick C, Anugu P, Musani S, Weiss ST, Burchard EG, White MJ, Keys KL, Cucca F, Sidore C, Boehnke M, Fuchsberger C. PMID: 32519380; PMCID: PMC7449570.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
-
Differential asthma odds following respiratory infection in children from three minority populations. PLoS One. 2020; 15(5):e0231782.
Wohlford EM, Borrell LN, Elhawary JR, Plotkin B, Oh SS, Nuckton TJ, Eng C, Salazar S, LeNoir MA, Meade K, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Kumar R, Thyne S, Seibold MA, Rodríguez-Santana JR, Burchard EG. PMID: 32369487; PMCID: PMC7199930.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
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Lung Function in African American Children with Asthma Is Associated with Novel Regulatory Variants of the KIT Ligand KITLG/SCF and Gene-By-Air-Pollution Interaction. Genetics. 2020 07; 215(3):869-886.
Mak ACY, Sajuthi S, Joo J, Xiao S, Sleiman PM, White MJ, Lee EY, Saef B, Hu D, Gui H, Keys KL, Lurmann F, Jain D, Abecasis G, Kang HM, Nickerson DA, Germer S, Zody MC, Winterkorn L, Reeves C, Huntsman S, Eng C, Salazar S, Oh SS, Gilliland FD, Chen Z, Kumar R, Martínez FD, Wu AC, Ziv E, Hakonarson H, Himes BE, Williams LK, Seibold MA, Burchard EG. PMID: 32327564; PMCID: PMC7337089.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCellsPHPublic Health
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Development of a small panel of SNPs to infer ancestry in Chileans that distinguishes Aymara and Mapuche components. Biol Res. 2020 Apr 16; 53(1):15.
Verdugo RA, Di Genova A, Herrera L, Moraga M, Acuña M, Berríos S, Llop E, Valenzuela CY, Bustamante ML, Digman D, Symon A, Asenjo S, López P, Blanco A, Suazo J, Barozet E, Caba F, Villalón M, Alvarado S, Cáceres D, Salgado K, Portales P, Moreno-Estrada A, Gignoux CR, Sandoval K, Bustamante CD, Eng C, Huntsman S, Burchard EG, Loira N, Maass A, Cifuentes L. PMID: 32299502; PMCID: PMC7161194.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Type 2 and interferon inflammation strongly regulate SARS-CoV-2 related gene expression in the airway epithelium. bioRxiv. 2020 Apr 10.
Sajuthi SP, DeFord P, Jackson ND, Montgomery MT, Everman JL, Rios CL, Pruesse E, Nolin JD, Plender EG, Wechsler ME, Mak AC, Eng C, Salazar S, Medina V, Wohlford EM, Huntsman S, Nickerson DA, Germer S, Zody MC, Abecasis G, Kang HM, Rice KM, Kumar R, Oh S, Rodriguez-Santana J, Burchard EG, Seibold MA. PMID: 32511326; PMCID: PMC7239056.
View in:
PubMed Mentions:
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Population History and Gene Divergence in Native Mexicans Inferred from 76 Human Exomes. Mol Biol Evol. 2020 04 01; 37(4):994-1006.
Ávila-Arcos MC, McManus KF, Sandoval K, Rodríguez-Rodríguez JE, Villa-Islas V, Martin AR, Luisi P, Peñaloza-Espinosa RI, Eng C, Huntsman S, Burchard EG, Gignoux CR, Bustamante CD, Moreno-Estrada A. PMID: 31848607; PMCID: PMC7086176.
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
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Outdoor Air Pollution and New-Onset Airway Disease. An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2020 04; 17(4):387-398.
Thurston GD, Balmes JR, Garcia E, Gilliland FD, Rice MB, Schikowski T, Van Winkle LS, Annesi-Maesano I, Burchard EG, Carlsten C, Harkema JR, Khreis H, Kleeberger SR, Kodavanti UP, London SJ, McConnell R, Peden DB, Pinkerton KE, Reibman J, White CW. PMID: 32233861; PMCID: PMC7175976.
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PubMed Mentions:
67 Fields:
Translation:
HumansPHPublic Health
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Expression of SMARCD1 interacts with age in association with asthma control on inhaled corticosteroid therapy. Respir Res. 2020 Jan 28; 21(1):31.
McGeachie MJ, Sordillo JE, Dahlin A, Wang AL, Lutz SM, Tantisira KG, Panganiban R, Lu Q, Sajuthi S, Urbanek C, Kelly R, Saef B, Eng C, Oh SS, Kho AT, Croteau-Chonka DC, Weiss ST, Raby BA, Mak ACY, Rodriguez-Santana JR, Burchard EG, Seibold MA, Wu AC. PMID: 31992292; PMCID: PMC6988322.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
IL1RL1 gene variations are associated with asthma exacerbations in children and adolescents using inhaled corticosteroids. Allergy. 2020 04; 75(4):984-989.
Dijk FN, Vijverberg SJ, Hernandez-Pacheco N, Repnik K, Karimi L, Mitratza M, Farzan N, Nawijn MC, Burchard EG, Engelkes M, Verhamme KM, Potocnik U, Pino-Yanes M, Postma DS, Maitland-van der Zee AH, Koppelman GH. PMID: 31755552; PMCID: PMC7176513.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Atopic dermatitis, race, and genetics. J Allergy Clin Immunol. 2020 01; 145(1):108-110.
Kumar R, Seibold MA, Burchard EG. PMID: 31738993.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Identification of CFTR variants in Latino patients with cystic fibrosis from the Dominican Republic and Puerto Rico. Pediatr Pulmonol. 2020 02; 55(2):533-540.
Zeiger AM, McGarry ME, Mak ACY, Medina V, Salazar S, Eng C, Liu AK, Oh SS, Nuckton TJ, Jain D, Blackwell TW, Kang HM, Abecasis G, Oñate LC, Seibold MA, Burchard EG, Rodriguez-Santana J. PMID: 31665830; PMCID: PMC7571374.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma. Chest. 2019 12; 156(6):1068-1079.
Kachroo P, Hecker J, Chawes BL, Ahluwalia TS, Cho MH, Qiao D, Kelly RS, Chu SH, Virkud YV, Huang M, Barnes KC, Burchard EG, Eng C, Hu D, Celedón JC, Daya M, Levin AM, Gui H, Williams LK, Forno E, Mak ACY, Avila L, Soto-Quiros ME, Cloutier MM, Acosta-Pérez E, Canino G, Bønnelykke K, Bisgaard H, Raby BA, Lange C, Weiss ST, Lasky-Su JA, National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium. PMID: 31557467; PMCID: PMC6904857.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
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Ancestry-Dependent Enrichment of Deleterious Homozygotes in Runs of Homozygosity. Am J Hum Genet. 2019 10 03; 105(4):747-762.
Szpiech ZA, Mak ACY, White MJ, Hu D, Eng C, Burchard EG, Hernandez RD. PMID: 31543216; PMCID: PMC6817522.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
-
Bacterial salivary microbiome associates with asthma among african american children and young adults. Pediatr Pulmonol. 2019 12; 54(12):1948-1956.
Espuela-Ortiz A, Lorenzo-Diaz F, Baez-Ortega A, Eng C, Hernandez-Pacheco N, Oh SS, Lenoir M, Burchard EG, Flores C, Pino-Yanes M. PMID: 31496123; PMCID: PMC6851413.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
-
Author Correction: Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations. Nat Commun. 2019 Sep 04; 10(1):4082.
Daya M, Rafaels N, Brunetti TM, Chavan S, Levin AM, Shetty A, Gignoux CR, Boorgula MP, Wojcik G, Campbell M, Vergara C, Torgerson DG, Ortega VE, Doumatey A, Johnston HR, Acevedo N, Araujo MI, Avila PC, Belbin G, Bleecker E, Bustamante C, Caraballo L, Cruz A, Dunston GM, Eng C, Faruque MU, Ferguson TS, Figueiredo C, Ford JG, Gan W, Gourraud PA, Hansel NN, Hernandez RD, Herrera-Paz EF, Jiménez S, Kenny EE, Knight-Madden J, Kumar R, Lange LA, Lange EM, Lizee A, Maul P, Maul T, Mayorga A, Meyers D, Nicolae DL, O'Connor TD, Oliveira RR, Olopade CO, Olopade O, Qin ZS, Rotimi C, Vince N, Watson H, Wilks RJ, Wilson JG, Salzberg S, Ober C, Burchard EG, Williams LK, Beaty TH, Taub MA, Ruczinski I, Mathias RA, Barnes KC, CAAPA. PMID: 31484942; PMCID: PMC6726619.
View in:
PubMed Mentions:
1 Fields:
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The genetic diversity of multiple sclerosis risk among Hispanic and African American populations living in the United States. Mult Scler. 2020 10; 26(11):1329-1339.
Beecham AH, Amezcua L, Chinea A, Manrique CP, Rubi C, Isobe N, Lund BT, Santaniello A, Beecham GW, Burchard EG, Comabella M, Patsopoulos N, Fitzgerald K, Calabresi PA, De Jager P, Conti DV, Delgado SR, Oksenberg JR, McCauley JL. PMID: 31368393; PMCID: PMC6994382.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
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Racial/Ethnic-Specific Differences in the Effects of Inhaled Corticosteroid Use on Bronchodilator Response in Patients With Asthma. Clin Pharmacol Ther. 2019 11; 106(5):1133-1140.
Samedy-Bates LA, Oh SS, Nuckton TJ, Elhawary JR, White M, Elliot T, Zeiger AM, Eng C, Salazar S, LeNoir MA, Meade K, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Bibbins-Domingo K, Kumar R, Thyne S, Borrell LN, Rodriguez-Santana JR, Pino-Yanes M, Burchard EG. PMID: 31209858; PMCID: PMC6778006.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Meta-analysis of GWA studies provides new insights on the genetic architecture of skin pigmentation in recently admixed populations. BMC Genet. 2019 07 17; 20(1):59.
Lona-Durazo F, Hernandez-Pacheco N, Fan S, Zhang T, Choi J, Kovacs MA, Loftus SK, Le P, Edwards M, Fortes-Lima CA, Eng C, Huntsman S, Hu D, Gómez-Cabezas EJ, Marín-Padrón LC, Grauholm J, Mors O, Burchard EG, Norton HL, Pavan WJ, Brown KM, Tishkoff S, Pino-Yanes M, Beleza S, Marcheco-Teruel B, Parra EJ. PMID: 31315583; PMCID: PMC6637524.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
-
Ambient air pollution, asthma drug response, and telomere length in African American youth. J Allergy Clin Immunol. 2019 09; 144(3):839-845.e10.
Lee EY, Oh SS, White MJ, Eng CS, Elhawary JR, Borrell LN, Nuckton TJ, Zeiger AM, Keys KL, Mak ACY, Hu D, Huntsman S, Contreras MG, Samedy LA, Goddard PC, Salazar SL, Brigino-Buenaventura EN, Davis A, Meade KE, LeNoir MA, Lurmann FW, Burchard EG, Eisen EA, Balmes JR. PMID: 31247265; PMCID: PMC6938647.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCellsPHPublic Health
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In utero tobacco smoke exposure, DNA methylation, and asthma in Latino children. Environ Epidemiol. 2019 Jun; 3(3):e048.
Neophytou AM, Oh SS, Hu D, Huntsman S, Eng C, Rodríguez-Santana JR, Kumar R, Balmes JR, Eisen EA, Burchard EG. PMID: 31342008; PMCID: PMC6571182.
View in:
PubMed Mentions:
15
-
Functional genomics of CDHR3 confirms its role in HRV-C infection and childhood asthma exacerbations. J Allergy Clin Immunol. 2019 10; 144(4):962-971.
Everman JL, Sajuthi S, Saef B, Rios C, Stoner AM, Numata M, Hu D, Eng C, Oh S, Rodriguez-Santana J, Vladar EK, Voelker DR, Burchard EG, Seibold MA. PMID: 30930175; PMCID: PMC6766426.
View in:
PubMed Mentions:
39 Fields:
Translation:
HumansCells
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Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations. Nat Commun. 2019 02 20; 10(1):880.
Daya M, Rafaels N, Brunetti TM, Chavan S, Levin AM, Shetty A, Gignoux CR, Boorgula MP, Wojcik G, Campbell M, Vergara C, Torgerson DG, Ortega VE, Doumatey A, Johnston HR, Acevedo N, Araujo MI, Avila PC, Belbin G, Bleecker E, Bustamante C, Caraballo L, Cruz A, Dunston GM, Eng C, Faruque MU, Ferguson TS, Figueiredo C, Ford JG, Gan W, Gourraud PA, Hansel NN, Hernandez RD, Herrera-Paz EF, Jiménez S, Kenny EE, Knight-Madden J, Kumar R, Lange LA, Lange EM, Lizee A, Maul P, Maul T, Mayorga A, Meyers D, Nicolae DL, O'Connor TD, Oliveira RR, Olopade CO, Olopade O, Qin ZS, Rotimi C, Vince N, Watson H, Wilks RJ, Wilson JG, Salzberg S, Ober C, Burchard EG, Williams LK, Beaty TH, Taub MA, Ruczinski I, Mathias RA, Barnes KC, CAAPA. PMID: 30787307; PMCID: PMC6382865.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansCells
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Genome-wide association study of inhaled corticosteroid response in admixed children with asthma. Clin Exp Allergy. 2019 06; 49(6):789-798.
Hernandez-Pacheco N, Farzan N, Francis B, Karimi L, Repnik K, Vijverberg SJ, Soares P, Schieck M, Gorenjak M, Forno E, Eng C, Oh SS, Pérez-Méndez L, Berce V, Tavendale R, Samedy LA, Hunstman S, Hu D, Meade K, Farber HJ, Avila PC, Serebrisky D, Thyne SM, Brigino-Buenaventura E, Rodriguez-Cintron W, Sen S, Kumar R, Lenoir M, Rodriguez-Santana JR, Celedón JC, Mukhopadhyay S, Potocnik U, Pirmohamed M, Verhamme KM, Kabesch M, Palmer CNA, Hawcutt DB, Flores C, Maitland-van der Zee AH, Burchard EG, Pino-Yanes M. PMID: 30697902; PMCID: PMC7054824.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansCTClinical Trials
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Author Correction: Assembly of a pan-genome from deep sequencing of 910 humans of African descent. Nat Genet. 2019 02; 51(2):364.
Sherman RM, Forman J, Antonescu V, Puiu D, Daya M, Rafaels N, Boorgula MP, Chavan S, Vergara C, Ortega VE, Levin AM, Eng C, Yazdanbakhsh M, Wilson JG, Marrugo J, Lange LA, Williams LK, Watson H, Ware LB, Olopade CO, Olopade O, Oliveira RR, Ober C, Nicolae DL, Meyers DA, Mayorga A, Knight-Madden J, Hartert T, Hansel NN, Foreman MG, Ford JG, Faruque MU, Dunston GM, Caraballo L, Burchard EG, Bleecker ER, Araujo MI, Herrera-Paz EF, Campbell M, Foster C, Taub MA, Beaty TH, Ruczinski I, Mathias RA, Barnes KC, Salzberg SL. PMID: 30647471.
View in:
PubMed Mentions:
2 Fields:
-
Acculturation is associated with asthma burden and pulmonary function in Latino youth: The GALA II study. J Allergy Clin Immunol. 2019 05; 143(5):1914-1922.
Thakur N, Borrell LN, Ye M, Oh SS, Eng C, Meade K, Avila PC, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Kumar R, Bibbins-Domingo K, Thyne S, Sen S, Rodriguez-Santana JR, Burchard EG. PMID: 30682453; PMCID: PMC9186509.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
Identification of novel common breast cancer risk variants at the 6q25 locus among Latinas. Breast Cancer Res. 2019 01 14; 21(1):3.
Hoffman J, Fejerman L, Hu D, Huntsman S, Li M, John EM, Torres-Mejia G, Kushi L, Ding YC, Weitzel J, Neuhausen SL, Lott P, COLUMBUS Consortium, Echeverry M, Carvajal-Carmona L, Burchard E, Eng C, Long J, Zheng W, Olopade O, Huo D, Haiman C, Ziv E. PMID: 30642363; PMCID: PMC6332913.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Epigenome-wide meta-analysis of DNA methylation and childhood asthma. J Allergy Clin Immunol. 2019 06; 143(6):2062-2074.
Reese SE, Xu CJ, den Dekker HT, Lee MK, Sikdar S, Ruiz-Arenas C, Merid SK, Rezwan FI, Page CM, Ullemar V, Melton PE, Oh SS, Yang IV, Burrows K, Söderhäll C, Jima DD, Gao L, Arathimos R, Küpers LK, Wielscher M, Rzehak P, Lahti J, Laprise C, Madore AM, Ward J, Bennett BD, Wang T, Bell DA, BIOS consortium, Vonk JM, Håberg SE, Zhao S, Karlsson R, Hollams E, Hu D, Richards AJ, Bergström A, Sharp GC, Felix JF, Bustamante M, Gruzieva O, Maguire RL, Gilliland F, Baïz N, Nohr EA, Corpeleijn E, Sebert S, Karmaus W, Grote V, Kajantie E, Magnus MC, Örtqvist AK, Eng C, Liu AH, Kull I, Jaddoe VWV, Sunyer J, Kere J, Hoyo C, Annesi-Maesano I, Arshad SH, Koletzko B, Brunekreef B, Binder EB, Räikkönen K, Reischl E, Holloway JW, Jarvelin MR, Snieder H, Kazmi N, Breton CV, Murphy SK, Pershagen G, Anto JM, Relton CL, Schwartz DA, Burchard EG, Huang RC, Nystad W, Almqvist C, Henderson AJ, Melén E, Duijts L, Koppelman GH, London SJ. PMID: 30579849; PMCID: PMC6556405.
View in:
PubMed Mentions:
102 Fields:
Translation:
HumansCells
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Current Status and Future Opportunities in Lung Precision Medicine Research with a Focus on Biomarkers. An American Thoracic Society/National Heart, Lung, and Blood Institute Research Statement. Am J Respir Crit Care Med. 2018 12 15; 198(12):e116-e136.
Wu AC, Kiley JP, Noel PJ, Amur S, Burchard EG, Clancy JP, Galanter J, Inada M, Jones TK, Kropski JA, Loyd JE, Nogee LM, Raby BA, Rogers AJ, Schwartz DA, Sin DD, Spira A, Weiss ST, Young LR, Himes BE. PMID: 30640517; PMCID: PMC6835090.
View in:
PubMed Mentions:
32 Fields:
Translation:
Humans
-
Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation. JAMA. 2018 12 11; 320(22):2354-2364.
Choi SH, Weng LC, Roselli C, Lin H, Haggerty CM, Shoemaker MB, Barnard J, Arking DE, Chasman DI, Albert CM, Chaffin M, Tucker NR, Smith JD, Gupta N, Gabriel S, Margolin L, Shea MA, Shaffer CM, Yoneda ZT, Boerwinkle E, Smith NL, Silverman EK, Redline S, Vasan RS, Burchard EG, Gogarten SM, Laurie C, Blackwell TW, Abecasis G, Carey DJ, Fornwalt BK, Smelser DT, Baras A, Dewey FE, Jaquish CE, Papanicolaou GJ, Sotoodehnia N, Van Wagoner DR, Psaty BM, Kathiresan S, Darbar D, Alonso A, Heckbert SR, Chung MK, Roden DM, Benjamin EJ, Murray MF, Lunetta KL, Lubitz SA, Ellinor PT, DiscovEHR study and the NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. PMID: 30535219; PMCID: PMC6436530.
View in:
PubMed Mentions:
89 Fields:
Translation:
Humans
-
Novel susceptibility variants at the ERG locus for childhood acute lymphoblastic leukemia in Hispanics. Blood. 2019 02 14; 133(7):724-729.
Qian M, Xu H, Perez-Andreu V, Roberts KG, Zhang H, Yang W, Zhang S, Zhao X, Smith C, Devidas M, Gastier-Foster JM, Raetz E, Larsen E, Burchard EG, Winick N, Bowman WP, Martin PL, Borowitz M, Wood B, Antillon-Klussmann F, Pui CH, Mullighan CG, Evans WE, Hunger SP, Relling MV, Loh ML, Yang JJ. PMID: 30510082; PMCID: PMC6376278.
View in:
PubMed Mentions:
32 Fields:
Translation:
Humans
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Genetic loci determining total immunoglobulin E levels from birth through adulthood. Allergy. 2019 03; 74(3):621-625.
Yao TC, Chung RH, Lin CY, Tsai PC, Chang WC, Yeh KW, Tsai MH, Liao SL, Hua MC, Lai SH, Chen LC, Chang SW, Yu YW, Hsu JY, Chang SC, Cheng WC, Hu D, Hong X, Burchard EG, Wang X, Tzeng JY, Tsai HJ, Huang JL. PMID: 30378687.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Assembly of a pan-genome from deep sequencing of 910 humans of African descent. Nat Genet. 2019 01; 51(1):30-35.
Sherman RM, Forman J, Antonescu V, Puiu D, Daya M, Rafaels N, Boorgula MP, Chavan S, Vergara C, Ortega VE, Levin AM, Eng C, Yazdanbakhsh M, Wilson JG, Marrugo J, Lange LA, Williams LK, Watson H, Ware LB, Olopade CO, Olopade O, Oliveira RR, Ober C, Nicolae DL, Meyers DA, Mayorga A, Knight-Madden J, Hartert T, Hansel NN, Foreman MG, Ford JG, Faruque MU, Dunston GM, Caraballo L, Burchard EG, Bleecker ER, Araujo MI, Herrera-Paz EF, Campbell M, Foster C, Taub MA, Beaty TH, Ruczinski I, Mathias RA, Barnes KC, Salzberg SL. PMID: 30455414; PMCID: PMC6309586.
View in:
PubMed Mentions:
164 Fields:
Translation:
Humans
-
Novel locus for atopic dermatitis in African Americans and replication in European Americans. J Allergy Clin Immunol. 2019 03; 143(3):1229-1231.
Almoguera B, Vazquez L, Mentch F, March ME, Connolly JJ, Peissig PL, Linneman JG, Plaza-Serón MDC, Pino-Yanes M, Burchard EG, Brilliant M, Sleiman P, Hakonarson H. PMID: 30414857.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Integrative approach identifies corticosteroid response variant in diverse populations with asthma. J Allergy Clin Immunol. 2019 05; 143(5):1791-1802.
Levin AM, Gui H, Hernandez-Pacheco N, Yang M, Xiao S, Yang JJ, Hochstadt S, Barczak AJ, Eckalbar WL, Rynkowski D, Samedy LA, Kwok PY, Pino-Yanes M, Erle DJ, Lanfear DE, Burchard EG, Williams LK. PMID: 30367910; PMCID: PMC6482107.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
-
A genome-wide association and admixture mapping study of bronchodilator drug response in African Americans with asthma. Pharmacogenomics J. 2019 06; 19(3):249-259.
Spear ML, Hu D, Pino-Yanes M, Huntsman S, Eng C, Levin AM, Ortega VE, White MJ, McGarry ME, Thakur N, Galanter J, Mak ACY, Oh SS, Ampleford E, Peters SP, Davis A, Kumar R, Farber HJ, Meade K, Avila PC, Serebrisky D, Lenoir MA, Brigino-Buenaventura E, Cintron WR, Thyne SM, Rodriguez-Santana JR, Ford JG, Chapela R, Estrada AM, Sandoval K, Seibold MA, Winkler CA, Bleecker ER, Myers DA, Williams LK, Hernandez RD, Torgerson DG, Burchard EG. PMID: 30206298; PMCID: PMC6414286.
View in:
PubMed Mentions:
33 Fields:
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An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos. J Allergy Clin Immunol. 2019 03; 143(3):957-969.
Gignoux CR, Torgerson DG, Pino-Yanes M, Uricchio LH, Galanter J, Roth LA, Eng C, Hu D, Nguyen EA, Huntsman S, Mathias RA, Kumar R, Rodriguez-Santana J, Thakur N, Oh SS, McGarry M, Moreno-Estrada A, Sandoval K, Winkler CA, Seibold MA, Padhukasahasram B, Conti DV, Farber HJ, Avila P, Brigino-Buenaventura E, Lenoir M, Meade K, Serebrisky D, Borrell LN, Rodriguez-Cintron W, Thyne S, Joubert BR, Romieu I, Levin AM, Sienra-Monge JJ, Del Rio-Navarro BE, Gan W, Raby BA, Weiss ST, Bleecker E, Meyers DA, Martinez FJ, Gauderman WJ, Gilliland F, London SJ, Bustamante CD, Nicolae DL, Ober C, Sen S, Barnes K, Williams LK, Hernandez RD, Burchard EG. PMID: 30201514; PMCID: PMC6927816.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
-
Genetic Determinants of Telomere Length in African American Youth. Sci Rep. 2018 09 05; 8(1):13265.
Zeiger AM, White MJ, Eng C, Oh SS, Witonsky J, Goddard PC, Contreras MG, Elhawary JR, Hu D, Mak ACY, Lee EY, Keys KL, Samedy LA, Risse-Adams O, Magaña J, Huntsman S, Salazar S, Davis A, Meade K, Brigino-Buenaventura E, LeNoir MA, Farber HJ, Bibbins-Domingo K, Borrell LN, Burchard EG. PMID: 30185882; PMCID: PMC6125592.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis. Nat Genet. 2018 09; 50(9):1343.
Waage J, Standl M, Curtin JA, Jessen LE, Thorsen J, Tian C, Schoettler N, 23andMe Research Team, AAGC collaborators, Flores C, Abdellaoui A, Ahluwalia TS, Alves AC, Amaral AFS, Antó JM, Arnold A, Barreto-Luis A, Baurecht H, van Beijsterveldt CEM, Bleecker ER, Bonàs-Guarch S, Boomsma DI, Brix S, Bunyavanich S, Burchard EG, Chen Z, Curjuric I, Custovic A, den Dekker HT, Dharmage SC, Dmitrieva J, Duijts L, Ege MJ, Gauderman WJ, Georges M, Gieger C, Gilliland F, Granell R, Gui H, Hansen T, Heinrich J, Henderson J, Hernandez-Pacheco N, Holt P, Imboden M, Jaddoe VWV, Jarvelin MR, Jarvis DL, Jensen KK, Jónsdóttir I, Kabesch M, Kaprio J, Kumar A, Lee YA, Levin AM, Li X, Lorenzo-Diaz F, Melén E, Mercader JM, Meyers DA, Myers R, Nicolae DL, Nohr EA, Palviainen T, Paternoster L, Pennell CE, Pershagen G, Pino-Yanes M, Probst-Hensch NM, Rüschendorf F, Simpson A, Stefansson K, Sunyer J, Sveinbjornsson G, Thiering E, Thompson PJ, Torrent M, Torrents D, Tung JY, Wang CA, Weidinger S, Weiss S, Willemsen G, Williams LK, Ober C, Hinds DA, Ferreira MA, Bisgaard H, Strachan DP, Bønnelykke K. PMID: 30116036.
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PubMed Mentions: Fields:
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Ancestry and genetic associations with bronchopulmonary dysplasia in preterm infants. Am J Physiol Lung Cell Mol Physiol. 2018 11 01; 315(5):L858-L869.
Torgerson DG, Ballard PL, Keller RL, Oh SS, Huntsman S, Hu D, Eng C, Burchard EG, Ballard RA, TOLSURF Study Group. PMID: 30113228; PMCID: PMC6295513.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function. Nat Commun. 2018 07 30; 9(1):2976.
Wyss AB, Sofer T, Lee MK, Terzikhan N, Nguyen JN, Lahousse L, Latourelle JC, Smith AV, Bartz TM, Feitosa MF, Gao W, Ahluwalia TS, Tang W, Oldmeadow C, Duan Q, de Jong K, Wojczynski MK, Wang XQ, Noordam R, Hartwig FP, Jackson VE, Wang T, Obeidat M, Hobbs BD, Huan T, Gui H, Parker MM, Hu D, Mogil LS, Kichaev G, Jin J, Graff M, Harris TB, Kalhan R, Heckbert SR, Paternoster L, Burkart KM, Liu Y, Holliday EG, Wilson JG, Vonk JM, Sanders JL, Barr RG, de Mutsert R, Menezes AMB, Adams HHH, van den Berge M, Joehanes R, Levin AM, Liberto J, Launer LJ, Morrison AC, Sitlani CM, Celedón JC, Kritchevsky SB, Scott RJ, Christensen K, Rotter JI, Bonten TN, Wehrmeister FC, Bossé Y, Xiao S, Oh S, Franceschini N, Brody JA, Kaplan RC, Lohman K, McEvoy M, Province MA, Rosendaal FR, Taylor KD, Nickle DC, Williams LK, Burchard EG, Wheeler HE, Sin DD, Gudnason V, North KE, Fornage M, Psaty BM, Myers RH, O'Connor G, Hansen T, Laurie CC, Cassano PA, Sung J, Kim WJ, Attia JR, Lange L, Boezen HM, Thyagarajan B, Rich SS, Mook-Kanamori DO, Horta BL, Uitterlinden AG, Im HK, Cho MH, Brusselle GG, Gharib SA, Dupuis J, Manichaikul A, London SJ. PMID: 30061609; PMCID: PMC6065313.
View in:
PubMed Mentions:
69 Fields:
Translation:
Humans
-
Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis. Nat Genet. 2018 08; 50(8):1072-1080.
Waage J, Standl M, Curtin JA, Jessen LE, Thorsen J, Tian C, Schoettler N, 23andMe Research Team, AAGC collaborators, Flores C, Abdellaoui A, Ahluwalia TS, Alves AC, Amaral AFS, Antó JM, Arnold A, Barreto-Luis A, Baurecht H, van Beijsterveldt CEM, Bleecker ER, Bonàs-Guarch S, Boomsma DI, Brix S, Bunyavanich S, Burchard EG, Chen Z, Curjuric I, Custovic A, den Dekker HT, Dharmage SC, Dmitrieva J, Duijts L, Ege MJ, Gauderman WJ, Georges M, Gieger C, Gilliland F, Granell R, Gui H, Hansen T, Heinrich J, Henderson J, Hernandez-Pacheco N, Holt P, Imboden M, Jaddoe VWV, Jarvelin MR, Jarvis DL, Jensen KK, Jónsdóttir I, Kabesch M, Kaprio J, Kumar A, Lee YA, Levin AM, Li X, Lorenzo-Diaz F, Melén E, Mercader JM, Meyers DA, Myers R, Nicolae DL, Nohr EA, Palviainen T, Paternoster L, Pennell CE, Pershagen G, Pino-Yanes M, Probst-Hensch NM, Rüschendorf F, Simpson A, Stefansson K, Sunyer J, Sveinbjornsson G, Thiering E, Thompson PJ, Torrent M, Torrents D, Tung JY, Wang CA, Weidinger S, Weiss S, Willemsen G, Williams LK, Ober C, Hinds DA, Ferreira MA, Bisgaard H, Strachan DP, Bønnelykke K. PMID: 30013184; PMCID: PMC7068780.
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PubMed Mentions:
51 Fields:
Translation:
Humans
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17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use. Allergy. 2018 10; 73(10):2083-2088.
Farzan N, Vijverberg SJ, Hernandez-Pacheco N, Bel EHD, Berce V, Bønnelykke K, Bisgaard H, Burchard EG, Canino G, Celedón JC, Chew FT, Chiang WC, Cloutier MM, Forno E, Francis B, Hawcutt DB, Herrera-Luis E, Kabesch M, Karimi L, Melén E, Mukhopadhyay S, Merid SK, Palmer CN, Pino-Yanes M, Pirmohamed M, Potocnik U, Repnik K, Schieck M, Sevelsted A, Sio YY, Smyth RL, Soares P, Söderhäll C, Tantisira KG, Tavendale R, Tse SM, Turner S, Verhamme KM, Maitland-van der Zee AH. PMID: 29885281; PMCID: PMC6220986.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma. Am J Respir Crit Care Med. 2018 06 15; 197(12):1552-1564.
Mak ACY, White MJ, Eckalbar WL, Szpiech ZA, Oh SS, Pino-Yanes M, Hu D, Goddard P, Huntsman S, Galanter J, Wu AC, Himes BE, Germer S, Vogel JM, Bunting KL, Eng C, Salazar S, Keys KL, Liberto J, Nuckton TJ, Nguyen TA, Torgerson DG, Kwok PY, Levin AM, Celedón JC, Forno E, Hakonarson H, Sleiman PM, Dahlin A, Tantisira KG, Weiss ST, Serebrisky D, Brigino-Buenaventura E, Farber HJ, Meade K, Lenoir MA, Avila PC, Sen S, Thyne SM, Rodriguez-Cintron W, Winkler CA, Moreno-Estrada A, Sandoval K, Rodriguez-Santana JR, Kumar R, Williams LK, Ahituv N, Ziv E, Seibold MA, Darnell RB, Zaitlen N, Hernandez RD, Burchard EG, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. PMID: 29509491; PMCID: PMC6006403.
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PubMed Mentions:
58 Fields:
Translation:
Humans
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Secondhand smoke exposure and asthma outcomes among African-American and Latino children with asthma. Thorax. 2018 11; 73(11):1041-1048.
Neophytou AM, Oh SS, White MJ, Mak ACY, Hu D, Huntsman S, Eng C, Serebrisky D, Borrell LN, Farber HJ, Meade K, Davis A, Avila PC, Thyne SM, Rodríguez-Cintrón W, Rodríguez-Santana JR, Kumar R, Brigino-Buenaventura E, Sen S, Lenoir MA, Williams LK, Benowitz NL, Balmes JR, Eisen EA, Burchard EG. PMID: 29899038; PMCID: PMC6225993.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansPHPublic Health
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Optimized distributed systems achieve significant performance improvement on sorted merging of massive VCF files. Gigascience. 2018 06 01; 7(6).
Sun X, Gao J, Jin P, Eng C, Burchard EG, Beaty TH, Ruczinski I, Mathias RA, Barnes K, Wang F, Qin ZS, CAAPA consortium. PMID: 29762754; PMCID: PMC6007233.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
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Variants in genes coding for glutathione S-transferases and asthma outcomes in children. Pharmacogenomics. 2018 06 01; 19(8):707-713.
Turner S, Francis B, Wani N, Vijverberg S, Pino-Yanes M, Mukhopadhyay S, Tavendale R, Palmer C, Burchard EG, Merid SK, Melén E, Maitland-van der Zee AH, The Pharmacogenomics In Childhood Asthma Consortium OBO. PMID: 29785881; PMCID: PMC6021964.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
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Correction to: Dual RNA-seq reveals viral infections in asthmatic children without respiratory illness which are associated with changes in the airway transcriptome. Genome Biol. 2018 04 10; 19(1):49.
Wesolowska-Andersen A, Everman JL, Davidson R, Rios C, Herrin R, Eng C, Janssen WJ, Liu AH, Oh SS, Kumar R, Fingerlin TE, Rodriguez-Santana J, Burchard EG, Seibold MA. PMID: 29636099; PMCID: PMC5891998.
View in:
PubMed Mentions:
2 Fields:
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Genomic insights into the origin and diversification of late maritime hunter-gatherers from the Chilean Patagonia. Proc Natl Acad Sci U S A. 2018 04 24; 115(17):E4006-E4012.
de la Fuente C, Ávila-Arcos MC, Galimany J, Carpenter ML, Homburger JR, Blanco A, Contreras P, Cruz Dávalos D, Reyes O, San Roman M, Moreno-Estrada A, Campos PF, Eng C, Huntsman S, Burchard EG, Malaspinas AS, Bustamante CD, Willerslev E, Llop E, Verdugo RA, Moraga M. PMID: 29632188; PMCID: PMC5924884.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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Dysregulated invertebrate tropomyosin-dectin-1 interaction confers susceptibility to allergic diseases. Sci Immunol. 2018 02 23; 3(20).
Gour N, Lajoie S, Smole U, White M, Hu D, Goddard P, Huntsman S, Eng C, Mak A, Oh S, Kim JH, Sharma A, Plante S, Salem IH, Resch Y, Xiao X, Yao N, Singh A, Vrtala S, Chakir J, Burchard EG, Lane AP, Wills-Karp M. PMID: 29475849; PMCID: PMC5956913.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues. Genome Biol. 2018 02 15; 19(1):36.
Mangul S, Yang HT, Strauli N, Gruhl F, Porath HT, Hsieh K, Chen L, Daley T, Christenson S, Wesolowska-Andersen A, Spreafico R, Rios C, Eng C, Smith AD, Hernandez RD, Ophoff RA, Santana JR, Levanon EY, Woodruff PG, Burchard E, Seibold MA, Shifman S, Eskin E, Zaitlen N. PMID: 29548336; PMCID: PMC5857127.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium. Int J Epidemiol. 2018 02 01; 47(1):22-23u.
Felix JF, Joubert BR, Baccarelli AA, Sharp GC, Almqvist C, Annesi-Maesano I, Arshad H, Baïz N, Bakermans-Kranenburg MJ, Bakulski KM, Binder EB, Bouchard L, Breton CV, Brunekreef B, Brunst KJ, Burchard EG, Bustamante M, Chatzi L, Cheng Munthe-Kaas M, Corpeleijn E, Czamara D, Dabelea D, Davey Smith G, De Boever P, Duijts L, Dwyer T, Eng C, Eskenazi B, Everson TM, Falahi F, Fallin MD, Farchi S, Fernandez MF, Gao L, Gaunt TR, Ghantous A, Gillman MW, Gonseth S, Grote V, Gruzieva O, Håberg SE, Herceg Z, Hivert MF, Holland N, Holloway JW, Hoyo C, Hu D, Huang RC, Huen K, Järvelin MR, Jima DD, Just AC, Karagas MR, Karlsson R, Karmaus W, Kechris KJ, Kere J, Kogevinas M, Koletzko B, Koppelman GH, Küpers LK, Ladd-Acosta C, Lahti J, Lambrechts N, Langie SAS, Lie RT, Liu AH, Magnus MC, Magnus P, Maguire RL, Marsit CJ, McArdle W, Melén E, Melton P, Murphy SK, Nawrot TS, Nisticò L, Nohr EA, Nordlund B, Nystad W, Oh SS, Oken E, Page CM, Perron P, Pershagen G, Pizzi C, Plusquin M, Raikkonen K, Reese SE, Reischl E, Richiardi L, Ring S, Roy RP, Rzehak P, Schoeters G, Schwartz DA, Sebert S, Snieder H, Sørensen TIA, Starling AP, Sunyer J, Taylor JA, Tiemeier H, Ullemar V, Vafeiadi M, Van Ijzendoorn MH, Vonk JM, Vriens A, Vrijheid M, Wang P, Wiemels JL, Wiemels JL, Wilcox AJ, Wright RJ, Xu CJ, Xu Z, Yang IV, Yousefi P, Zhang H, Zhang W, Zhao S, Agha G, Relton CL, Jaddoe VWV, London SJ. PMID: 29025028; PMCID: PMC5837319.
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PubMed Mentions:
76 Fields:
Translation:
HumansCellsPHPublic Health
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A genome-wide association study identifies only two ancestry specific variants associated with spontaneous preterm birth. Sci Rep. 2018 01 09; 8(1):226.
Rappoport N, Toung J, Hadley D, Wong RJ, Fujioka K, Reuter J, Abbott CW, Oh S, Hu D, Eng C, Huntsman S, Bodian DL, Niederhuber JE, Hong X, Zhang G, Sikora-Wohfeld W, Gignoux CR, Wang H, Oehlert J, Jelliffe-Pawlowski LL, Gould JB, Darmstadt GL, Wang X, Bustamante CD, Snyder MP, Ziv E, Patsopoulos NA, Muglia LJ, Burchard E, Shaw GM, O'Brodovich HM, Stevenson DK, Butte AJ, Sirota M. PMID: 29317701; PMCID: PMC5760643.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Nat Genet. 2018 01; 50(1):42-53.
Demenais F, Margaritte-Jeannin P, Barnes KC, Cookson WOC, Altmüller J, Ang W, Barr RG, Beaty TH, Becker AB, Beilby J, Bisgaard H, Bjornsdottir US, Bleecker E, Bønnelykke K, Boomsma DI, Bouzigon E, Brightling CE, Brossard M, Brusselle GG, Burchard E, Burkart KM, Bush A, Chan-Yeung M, Chung KF, Couto Alves A, Curtin JA, Custovic A, Daley D, de Jongste JC, Del-Rio-Navarro BE, Donohue KM, Duijts L, Eng C, Eriksson JG, Farrall M, Fedorova Y, Feenstra B, Ferreira MA, Australian Asthma Genetics Consortium (AAGC) collaborators, Freidin MB, Gajdos Z, Gauderman J, Gehring U, Geller F, Genuneit J, Gharib SA, Gilliland F, Granell R, Graves PE, Gudbjartsson DF, Haahtela T, Heckbert SR, Heederik D, Heinrich J, Heliövaara M, Henderson J, Himes BE, Hirose H, Hirschhorn JN, Hofman A, Holt P, Hottenga J, Hudson TJ, Hui J, Imboden M, Ivanov V, Jaddoe VWV, James A, Janson C, Jarvelin MR, Jarvis D, Jones G, Jonsdottir I, Jousilahti P, Kabesch M, Kähönen M, Kantor DB, Karunas AS, Khusnutdinova E, Koppelman GH, Kozyrskyj AL, Kreiner E, Kubo M, Kumar R, Kumar A, Kuokkanen M, Lahousse L, Laitinen T, Laprise C, Lathrop M, Lau S, Lee YA, Lehtimäki T, Letort S, Levin AM, Li G, Liang L, Loehr LR, London SJ, Loth DW, Manichaikul A, Marenholz I, Martinez FJ, Matheson MC, Mathias RA, Matsumoto K, Mbarek H, McArdle WL, Melbye M, Melén E, Meyers D, Michel S, Mohamdi H, Musk AW, Myers RA, Nieuwenhuis MAE, Noguchi E, O'Connor GT, Ogorodova LM, Palmer CD, Palotie A, Park JE, Pennell CE, Pershagen G, Polonikov A, Postma DS, Probst-Hensch N, Puzyrev VP, Raby BA, Raitakari OT, Ramasamy A, Rich SS, Robertson CF, Romieu I, Salam MT, Salomaa V, Schlünssen V, Scott R, Selivanova PA, Sigsgaard T, Simpson A, Siroux V, Smith LJ, Solodilova M, Standl M, Stefansson K, Strachan DP, Stricker BH, Takahashi A, Thompson PJ, Thorleifsson G, Thorsteinsdottir U, Tiesler CMT, Torgerson DG, Tsunoda T, Uitterlinden AG, van der Valk RJP, Vaysse A, Vedantam S, von Berg A, von Mutius E, Vonk JM, Waage J, Wareham NJ, Weiss ST, White WB, Wickman M, Widén E, Willemsen G, Williams LK, Wouters IM, Yang JJ, Zhao JH, Moffatt MF, Ober C, Nicolae DL. PMID: 29273806; PMCID: PMC5901974.
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PubMed Mentions:
244 Fields:
Translation:
HumansCells
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An ancestry-based approach for detecting interactions. Genet Epidemiol. 2018 02; 42(1):49-63.
Park DS, Eskin I, Kang EY, Gamazon ER, Eng C, Gignoux CR, Galanter JM, Burchard E, Ye CJ, Aschard H, Eskin E, Halperin E, Zaitlen N. PMID: 29114909; PMCID: PMC6065511.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Pulmonary function disparities exist and persist in Hispanic patients with cystic fibrosis: A longitudinal analysis. Pediatr Pulmonol. 2017 Dec; 52(12):1550-1557.
McGarry ME, Neuhaus JM, Nielson DW, Burchard E, Ly NP. PMID: 29082671; PMCID: PMC5693693.
View in:
PubMed Mentions:
21 Fields:
Translation:
Humans
-
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
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Apolipoprotein E epsilon 4 (APOE-ε4) genotype is associated with decreased 6-month verbal memory performance after mild traumatic brain injury. Brain Behav. 2017 09; 7(9):e00791.
Yue JK, Robinson CK, Burke JF, Winkler EA, Deng H, Cnossen MC, Lingsma HF, Ferguson AR, McAllister TW, Rosand J, Burchard EG, Sorani MD, Sharma S, Nielson JL, Satris GG, Talbott JF, Tarapore PE, Korley FK, Wang KKW, Yuh EL, Mukherjee P, Diaz-Arrastia R, Valadka AB, Okonkwo DO, Manley GT, TRACK-TBI Investigators. PMID: 28948085; PMCID: PMC5607554.
View in:
PubMed Mentions:
20 Fields:
Translation:
Humans
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American Thoracic Society/National Heart, Lung, and Blood Institute Asthma-Chronic Obstructive Pulmonary Disease Overlap Workshop Report. Am J Respir Crit Care Med. 2017 08 01; 196(3):375-381.
Woodruff PG, van den Berge M, Boucher RC, Brightling C, Burchard EG, Christenson SA, Han MK, Holtzman MJ, Kraft M, Lynch DA, Martinez FD, Reddel HK, Sin DD, Washko GR, Wenzel SE, Punturieri A, Freemer MM, Wise RA. PMID: 28636425; PMCID: PMC5549872.
View in:
PubMed Mentions:
48 Fields:
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PAI-1 gain-of-function genotype, factors increasing PAI-1 levels, and airway obstruction: The GALA II Cohort. Clin Exp Allergy. 2017 Sep; 47(9):1150-1158.
Sherenian MG, Cho SH, Levin A, Min JY, Oh SS, Hu D, Galanter J, Sen S, Huntsman S, Eng C, Rodriguez-Santana JR, Serebrisky D, Avila PC, Kalhan R, Smith LJ, Borrell LN, Seibold MA, Keoki Williams L, Burchard EG, Kumar R. PMID: 28543872; PMCID: PMC5764093.
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PubMed Mentions: Fields:
Translation:
Humans
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Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium. Pharmacogenomics. 2017 07; 18(10):931-943.
Farzan N, Vijverberg SJ, Andiappan AK, Arianto L, Berce V, Blanca-López N, Bisgaard H, Bønnelykke K, Burchard EG, Campo P, Canino G, Carleton B, Celedón JC, Chew FT, Chiang WC, Cloutier MM, Daley D, Den Dekker HT, Dijk FN, Duijts L, Flores C, Forno E, Hawcutt DB, Hernandez-Pacheco N, de Jongste JC, Kabesch M, Koppelman GH, Manolopoulos VG, Melén E, Mukhopadhyay S, Nilsson S, Palmer CN, Pino-Yanes M, Pirmohamed M, Potocnik U, Raaijmakers JA, Repnik K, Schieck M, Sio YY, Smyth RL, Szalai C, Tantisira KG, Turner S, van der Schee MP, Verhamme KM, Maitland-van der Zee AH. PMID: 28639505; PMCID: PMC5967359.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
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Self-reported racial/ethnic discrimination and bronchodilator response in African American youth with asthma. PLoS One. 2017; 12(6):e0179091.
Carlson S, Borrell LN, Eng C, Nguyen M, Thyne S, LeNoir MA, Burke-Harris N, Burchard EG, Thakur N. PMID: 28609485; PMCID: PMC5469454.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
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An American Thoracic Society/National Heart, Lung, and Blood Institute Workshop Report: Addressing Respiratory Health Equality in the United States. Ann Am Thorac Soc. 2017 May; 14(5):814-826.
Celedón JC, Burchard EG, Schraufnagel D, Castillo-Salgado C, Schenker M, Balmes J, Neptune E, Cummings KJ, Holguin F, Riekert KA, Wisnivesky JP, Garcia JGN, Roman J, Kittles R, Ortega VE, Redline S, Mathias R, Thomas A, Samet J, Ford JG, American Thoracic Society and the National Heart, Lung, and Blood Institute. PMID: 28459618; PMCID: PMC6207141.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
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A meta-analysis of genome-wide association studies of asthma in Puerto Ricans. Eur Respir J. 2017 05; 49(5).
Yan Q, Brehm J, Pino-Yanes M, Forno E, Lin J, Oh SS, Acosta-Perez E, Laurie CC, Cloutier MM, Raby BA, Stilp AM, Sofer T, Hu D, Huntsman S, Eng CS, Conomos MP, Rastogi D, Rice K, Canino G, Chen W, Barr RG, Burchard EG, Celedón JC. PMID: 28461288; PMCID: PMC5527708.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Identification of a novel locus associated with skin colour in African-admixed populations. Sci Rep. 2017 03 16; 7:44548.
Hernandez-Pacheco N, Flores C, Alonso S, Eng C, Mak AC, Hunstman S, Hu D, White MJ, Oh SS, Meade K, Farber HJ, Avila PC, Serebrisky D, Thyne SM, Brigino-Buenaventura E, Rodriguez-Cintron W, Sen S, Kumar R, Lenoir M, Rodriguez-Santana JR, Burchard EG, Pino-Yanes M. PMID: 28300201; PMCID: PMC5353593.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
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Correcting for cell-type heterogeneity in DNA methylation: a comprehensive evaluation. Nat Methods. 2017 02 28; 14(3):218-219.
Rahmani E, Zaitlen N, Baran Y, Eng C, Hu D, Galanter J, Oh S, Burchard EG, Eskin E, Zou J, Halperin E. PMID: 28245214; PMCID: PMC5548185.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Suggestive association between variants in IL1RAPL and asthma symptoms in Latin American children. Eur J Hum Genet. 2017 04; 25(4):439-445.
Marques CR, Costa GN, da Silva TM, Oliveira P, Cruz AA, Alcantara-Neves NM, Fiaccone RL, Horta BL, Hartwig FP, Burchard EG, Pino-Yanes M, Rodrigues LC, Lima-Costa MF, Pereira AC, Gouveia MH, Sant Anna HP, Tarazona-Santos E, Lima Barreto M, Figueiredo CA. PMID: 28120837; PMCID: PMC5386417.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
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Dual RNA-seq reveals viral infections in asthmatic children without respiratory illness which are associated with changes in the airway transcriptome. Genome Biol. 2017 01 19; 18(1):12.
Wesolowska-Andersen A, Everman JL, Davidson R, Rios C, Herrin R, Eng C, Janssen WJ, Liu AH, Oh SS, Kumar R, Fingerlin TE, Rodriguez-Santana J, Burchard EG, Seibold MA. PMID: 28103897; PMCID: PMC5244706.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansCells
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An epigenome-wide association study of total serum IgE in Hispanic children. J Allergy Clin Immunol. 2017 Aug; 140(2):571-577.
Chen W, Wang T, Pino-Yanes M, Forno E, Liang L, Yan Q, Hu D, Weeks DE, Baccarelli A, Acosta-Perez E, Eng C, Han YY, Boutaoui N, Laprise C, Davies GA, Hopkin JM, Moffatt MF, Cookson WOCM, Canino G, Burchard EG, Celedón JC. PMID: 28069425; PMCID: PMC5500449.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansCells
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Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures. Elife. 2017 01 03; 6.
Galanter JM, Gignoux CR, Oh SS, Torgerson D, Pino-Yanes M, Thakur N, Eng C, Hu D, Huntsman S, Farber HJ, Avila PC, Brigino-Buenaventura E, LeNoir MA, Meade K, Serebrisky D, Rodríguez-Cintrón W, Kumar R, Rodríguez-Santana JR, Seibold MA, Borrell LN, Burchard EG, Zaitlen N. PMID: 28044981; PMCID: PMC5207770.
View in:
PubMed Mentions:
92 Fields:
Translation:
HumansCellsPHPublic Health
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Genome-wide methylation data mirror ancestry information. Epigenetics Chromatin. 2017; 10:1.
Rahmani E, Shenhav L, Schweiger R, Yousefi P, Huen K, Eskenazi B, Eng C, Huntsman S, Hu D, Galanter J, Oh SS, Waldenberger M, Strauch K, Grallert H, Meitinger T, Gieger C, Holland N, Burchard EG, Zaitlen N, Halperin E. PMID: 28149326; PMCID: PMC5267476.
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PubMed Mentions:
59 Fields:
Translation:
HumansCells
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Breastfeeding associated with higher lung function in African American youths with asthma. J Asthma. 2017 Oct; 54(8):856-865.
Oh SS, Du R, Zeiger AM, McGarry ME, Hu D, Thakur N, Pino-Yanes M, Galanter JM, Eng C, Nishimura KK, Huntsman S, Farber HJ, Meade K, Avila P, Serebrisky D, Bibbins-Domingo K, Lenoir MA, Ford JG, Brigino-Buenaventura E, Rodriguez-Cintron W, Thyne SM, Sen S, Rodriguez-Santana JR, Williams K, Kumar R, Burchard EG. PMID: 27929698; PMCID: PMC6130885.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Perceived Discrimination Associated With Asthma and Related Outcomes in Minority Youth: The GALA II and SAGE II Studies. Chest. 2017 04; 151(4):804-812.
Thakur N, Barcelo NE, Borrell LN, Singh S, Eng C, Davis A, Meade K, LeNoir MA, Avila PC, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Thyne S, Rodriguez-Santana JR, Sen S, Bibbins-Domingo K, Burchard EG. PMID: 27916618; PMCID: PMC5472516.
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PubMed Mentions:
40 Fields:
Translation:
Humans
-
Towards Equity in Health: Researchers Take Stock. PLoS Med. 2016 Nov; 13(11):e1002186.
PLOS Medicine Editors, Rid A, Johansson MA, Leung G, Valantine H, Burchard EG, Oh SS, Zimmerman C. PMID: 27898673; PMCID: PMC5127492.
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PubMed Mentions:
6 Fields:
Translation:
Humans
-
The Effects of Migration and Assortative Mating on Admixture Linkage Disequilibrium. Genetics. 2017 01; 205(1):375-383.
Zaitlen N, Huntsman S, Hu D, Spear M, Eng C, Oh SS, White MJ, Mak A, Davis A, Meade K, Brigino-Buenaventura E, LeNoir MA, Bibbins-Domingo K, Burchard EG, Halperin E. PMID: 27879348; PMCID: PMC5223515.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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DRD2 C957T polymorphism is associated with improved 6-month verbal learning following traumatic brain injury. Neurogenetics. 2017 01; 18(1):29-38.
Yue JK, Winkler EA, Rick JW, Burke JF, McAllister TW, Oh SS, Burchard EG, Hu D, Rosand J, Temkin NR, Korley FK, Sorani MD, Ferguson AR, Lingsma HF, Sharma S, Robinson CK, Yuh EL, Tarapore PE, Wang KK, Puccio AM, Mukherjee P, Diaz-Arrastia R, Gordon WA, Valadka AB, Okonkwo DO, Manley GT, TRACK-TBI Investigators. PMID: 27826691; PMCID: PMC5588886.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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COMT Val158Met polymorphism is associated with post-traumatic stress disorder and functional outcome following mild traumatic brain injury. J Clin Neurosci. 2017 Jan; 35:109-116.
Winkler EA, Yue JK, Ferguson AR, Temkin NR, Stein MB, Barber J, Yuh EL, Sharma S, Satris GG, McAllister TW, Rosand J, Sorani MD, Lingsma HF, Tarapore PE, Burchard EG, Hu D, Eng C, Wang KK, Mukherjee P, Okonkwo DO, Diaz-Arrastia R, Manley GT, TRACK-TBI Investigators. PMID: 27769642; PMCID: PMC5588892.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome. Nat Commun. 2016 10 11; 7:12522.
Mathias RA, Taub MA, Gignoux CR, Fu W, Musharoff S, O'Connor TD, Vergara C, Torgerson DG, Pino-Yanes M, Shringarpure SS, Huang L, Rafaels N, Boorgula MP, Johnston HR, Ortega VE, Levin AM, Song W, Torres R, Padhukasahasram B, Eng C, Mejia-Mejia DA, Ferguson T, Qin ZS, Scott AF, Yazdanbakhsh M, Wilson JG, Marrugo J, Lange LA, Kumar R, Avila PC, Williams LK, Watson H, Ware LB, Olopade C, Olopade O, Oliveira R, Ober C, Nicolae DL, Meyers D, Mayorga A, Knight-Madden J, Hartert T, Hansel NN, Foreman MG, Ford JG, Faruque MU, Dunston GM, Caraballo L, Burchard EG, Bleecker E, Araujo MI, Herrera-Paz EF, Gietzen K, Grus WE, Bamshad M, Bustamante CD, Kenny EE, Hernandez RD, Beaty TH, Ruczinski I, Akey J, CAAPA, Barnes KC. PMID: 27725671; PMCID: PMC5062574.
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PubMed Mentions:
81 Fields:
Translation:
HumansCells
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Association of a PAI-1 Gene Polymorphism and Early Life Infections with Asthma Risk, Exacerbations, and Reduced Lung Function. PLoS One. 2016; 11(8):e0157848.
Cho SH, Min JY, Kim DY, Oh SS, Torgerson DR, Pino-Yanes M, Hu D, Sen S, Huntsman S, Eng C, Farber HJ, Rodriguez-Cintron W, Rodriguez-Santana JR, Serebrisky D, Thyne SM, Borrell LN, Williams LK, DuPont W, Seibold MA, Burchard EG, Avila PC, Kumar R. PMID: 27556405; PMCID: PMC4996454.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Predictive Properties of the Asthma Control Test and Its Component Questions for Severe Asthma Exacerbations. J Allergy Clin Immunol Pract. 2017 Jan - Feb; 5(1):121-127.e2.
Cajigal S, Wells KE, Peterson EL, Ahmedani BK, Yang JJ, Kumar R, Burchard EG, Williams LK. PMID: 27544712; PMCID: PMC5222777.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Maternal age and asthma in Latino populations. Clin Exp Allergy. 2016 11; 46(11):1398-1406.
Abid Z, Oh SS, Hu D, Sen S, Huntsman S, Eng C, Farber HJ, Rodriguez-Cintron W, Rodriguez-Santana JR, Serebrisky D, Avila PC, Thyne SM, Kim KA, Borrell LN, Williams LK, Seibold MA, Burchard EG, Kumar R. PMID: 27238356; PMCID: PMC5770153.
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PubMed Mentions:
4 Fields:
Translation:
HumansPHPublic Health
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Genetic Investigation Into the Differential Risk of Atrial Fibrillation Among Black and White Individuals. JAMA Cardiol. 2016 07 01; 1(4):442-50.
Roberts JD, Hu D, Heckbert SR, Alonso A, Dewland TA, Vittinghoff E, Liu Y, Psaty BM, Olgin JE, Magnani JW, Huntsman S, Burchard EG, Arking DE, Bibbins-Domingo K, Harris TB, Perez MV, Ziv E, Marcus GM. PMID: 27438321; PMCID: PMC5395094.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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What Ancestry Can Tell Us About the Genetic Origins of Inter-Ethnic Differences in Asthma Expression. Curr Allergy Asthma Rep. 2016 07; 16(8):53.
Hernandez-Pacheco N, Flores C, Oh SS, Burchard EG, Pino-Yanes M. PMID: 27393700.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Early-life ozone exposure associated with asthma without sensitization in Latino children. J Allergy Clin Immunol. 2016 12; 138(6):1703-1706.e1.
Nishimura KK, Iwanaga K, Oh SS, Pino-Yanes M, Eng C, Keswani A, Roth LA, Nguyen EA, Thyne SM, Farber HJ, Serebrisky D, Meade K, LeNoir MA, Rodriguez-Cintron W, Borrell LN, Bibbins-Domingo K, Lurmann F, Sen S, Rodriguez-Santana JR, Brigino-Buenaventura E, Avila PC, Balmes JR, Kumar R, Burchard EG. PMID: 27423496; PMCID: PMC5148667.
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PubMed Mentions:
11 Fields:
Translation:
HumansPHPublic Health
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Air Pollution and Lung Function in Minority Youth with Asthma in the GALA II (Genes-Environments and Admixture in Latino Americans) and SAGE II (Study of African Americans, Asthma, Genes, and Environments) Studies. Am J Respir Crit Care Med. 2016 06 01; 193(11):1271-80.
Neophytou AM, White MJ, Oh SS, Thakur N, Galanter JM, Nishimura KK, Pino-Yanes M, Torgerson DG, Gignoux CR, Eng C, Nguyen EA, Hu D, Mak AC, Kumar R, Seibold MA, Davis A, Farber HJ, Meade K, Avila PC, Serebrisky D, Lenoir MA, Brigino-Buenaventura E, Rodriguez-Cintron W, Bibbins-Domingo K, Thyne SM, Williams LK, Sen S, Gilliland FD, Gauderman WJ, Rodriguez-Santana JR, Lurmann F, Balmes JR, Eisen EA, Burchard EG. PMID: 26734713; PMCID: PMC4910900.
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PubMed Mentions:
38 Fields:
Translation:
HumansPHPublic Health
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Sensitization to mouse and cockroach allergens and asthma morbidity in urban minority youth: Genes-environments and Admixture in Latino American (GALA-II) and Study of African-Americans, Asthma, Genes, and Environments (SAGE-II). Ann Allergy Asthma Immunol. 2016 07; 117(1):43-49.e1.
Fishbein AB, Lee TA, Cai M, Oh SS, Eng C, Hu D, Huntsman S, Farber HJ, Serebrisky D, Silverberg J, Williams LK, Seibold MA, Sen S, Borrell LN, Avila P, Rodriguez-Cintron W, Rodriguez-Santana JR, Burchard EG, Kumar R. PMID: 27238578.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsPHPublic Health
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Novel genetic risk factors for asthma in African American children: Precision Medicine and the SAGE II Study. Immunogenetics. 2016 Jul; 68(6-7):391-400.
White MJ, Risse-Adams O, Goddard P, Contreras MG, Adams J, Hu D, Eng C, Oh SS, Davis A, Meade K, Brigino-Buenaventura E, LeNoir MA, Bibbins-Domingo K, Pino-Yanes M, Burchard EG. PMID: 27142222; PMCID: PMC4927336.
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PubMed Mentions:
36 Fields:
Translation:
Humans
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The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity. Science. 2016 Apr 01; 352(6281):99-103.
Chan PY, Carrera Silva EA, De Kouchkovsky D, Joannas LD, Hao L, Hu D, Huntsman S, Eng C, Licona-Limón P, Weinstein JS, Herbert DR, Craft JE, Flavell RA, Repetto S, Correale J, Burchard EG, Torgerson DG, Ghosh S, Rothlin CV. PMID: 27034374; PMCID: PMC4935984.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
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DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis. Am J Hum Genet. 2016 Apr 07; 98(4):680-96.
Joubert BR, Felix JF, Yousefi P, Bakulski KM, Just AC, Breton C, Reese SE, Markunas CA, Richmond RC, Xu CJ, Küpers LK, Oh SS, Hoyo C, Gruzieva O, Söderhäll C, Salas LA, Baïz N, Zhang H, Lepeule J, Ruiz C, Ligthart S, Wang T, Taylor JA, Duijts L, Sharp GC, Jankipersadsing SA, Nilsen RM, Vaez A, Fallin MD, Hu D, Litonjua AA, Fuemmeler BF, Huen K, Kere J, Kull I, Munthe-Kaas MC, Gehring U, Bustamante M, Saurel-Coubizolles MJ, Quraishi BM, Ren J, Tost J, Gonzalez JR, Peters MJ, Håberg SE, Xu Z, van Meurs JB, Gaunt TR, Kerkhof M, Corpeleijn E, Feinberg AP, Eng C, Baccarelli AA, Benjamin Neelon SE, Bradman A, Merid SK, Bergström A, Herceg Z, Hernandez-Vargas H, Brunekreef B, Pinart M, Heude B, Ewart S, Yao J, Lemonnier N, Franco OH, Wu MC, Hofman A, McArdle W, Van der Vlies P, Falahi F, Gillman MW, Barcellos LF, Kumar A, Wickman M, Guerra S, Charles MA, Holloway J, Auffray C, Tiemeier HW, Smith GD, Postma D, Hivert MF, Eskenazi B, Vrijheid M, Arshad H, Antó JM, Dehghan A, Karmaus W, Annesi-Maesano I, Sunyer J, Ghantous A, Pershagen G, Holland N, Murphy SK, DeMeo DL, Burchard EG, Ladd-Acosta C, Snieder H, Nystad W, Koppelman GH, Relton CL, Jaddoe VW, Wilcox A, Melén E, London SJ. PMID: 27040690; PMCID: PMC4833289.
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PubMed Mentions:
440 Fields:
Translation:
HumansCells
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Sparse PCA corrects for cell type heterogeneity in epigenome-wide association studies. Nat Methods. 2016 05; 13(5):443-5.
Rahmani E, Zaitlen N, Baran Y, Eng C, Hu D, Galanter J, Oh S, Burchard EG, Eskin E, Zou J, Halperin E. PMID: 27018579; PMCID: PMC5548182.
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PubMed Mentions:
133 Fields:
Translation:
HumansCells
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Assessing differences in inhaled corticosteroid response by self-reported race-ethnicity and genetic ancestry among asthmatic subjects. J Allergy Clin Immunol. 2016 05; 137(5):1364-1369.e2.
Wells KE, Cajigal S, Peterson EL, Ahmedani BK, Kumar R, Lanfear DE, Burchard EG, Williams LK. PMID: 27016472; PMCID: PMC5313277.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Racial Differences in Left Atrial Size: Results from the Coronary Artery Risk Development in Young Adults (CARDIA) Study. PLoS One. 2016; 11(3):e0151559.
Dewland TA, Bibbins-Domingo K, Lin F, Vittinghoff E, Foster E, Ogunyankin KO, Lima JA, Jacobs DR, Hu D, Burchard EG, Marcus GM. PMID: 26985672; PMCID: PMC4795666.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Making Precision Medicine Socially Precise. Take a Deep Breath. Am J Respir Crit Care Med. 2016 Feb 15; 193(4):348-50.
Oh SS, White MJ, Gignoux CR, Burchard EG. PMID: 26871667; PMCID: PMC4803087.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Childhood asthma exacerbations and the Arg16 β2-receptor polymorphism: A meta-analysis stratified by treatment. J Allergy Clin Immunol. 2016 07; 138(1):107-113.e5.
Turner S, Francis B, Vijverberg S, Pino-Yanes M, Maitland-van der Zee AH, Basu K, Bignell L, Mukhopadhyay S, Tavendale R, Palmer C, Hawcutt D, Pirmohamed M, Burchard EG, Lipworth B, Pharmacogenomics in Childhood Asthma Consortium. PMID: 26774659; PMCID: PMC4931969.
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PubMed Mentions:
28 Fields:
Translation:
Humans
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Diversity in Clinical and Biomedical Research: A Promise Yet to Be Fulfilled. PLoS Med. 2015 Dec; 12(12):e1001918.
Oh SS, Galanter J, Thakur N, Pino-Yanes M, Barcelo NE, White MJ, de Bruin DM, Greenblatt RM, Bibbins-Domingo K, Wu AH, Borrell LN, Gunter C, Powe NR, Burchard EG. PMID: 26671224; PMCID: PMC4679830.
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PubMed Mentions:
268 Fields:
Translation:
Humans
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A genome-wide association study of asthma symptoms in Latin American children. BMC Genet. 2015 Dec 03; 16:141.
Costa GN, Dudbridge F, Fiaccone RL, da Silva TM, Conceição JS, Strina A, Figueiredo CA, Magalhães WC, Rodrigues MR, Gouveia MH, Kehdy FS, Horimoto AR, Horta B, Burchard EG, Pino-Yanes M, Del Rio Navarro B, Romieu I, Hancock DB, London S, Lima-Costa MF, Pereira AC, Tarazona E, Rodrigues LC, Barreto ML. PMID: 26635092; PMCID: PMC4669662.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Powerful Tests for Multi-Marker Association Analysis Using Ensemble Learning. PLoS One. 2015; 10(11):e0143489.
Padhukasahasram B, Reddy CK, Levin AM, Burchard EG, Williams LK. PMID: 26619286; PMCID: PMC4664402.
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PubMed Mentions: Fields:
Translation:
Humans
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COMT Val 158 Met polymorphism is associated with nonverbal cognition following mild traumatic brain injury. Neurogenetics. 2016 Jan; 17(1):31-41.
Winkler EA, Yue JK, McAllister TW, Temkin NR, Oh SS, Burchard EG, Hu D, Ferguson AR, Lingsma HF, Burke JF, Sorani MD, Rosand J, Yuh EL, Barber J, Tarapore PE, Gardner RC, Sharma S, Satris GG, Eng C, Puccio AM, Wang KK, Mukherjee P, Valadka AB, Okonkwo DO, Diaz-Arrastia R, Manley GT, TRACK-TBI Investigators. PMID: 26576546; PMCID: PMC4988810.
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PubMed Mentions:
18 Fields:
Translation:
HumansCTClinical Trials
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Pacifiplex: an ancestry-informative SNP panel centred on Australia and the Pacific region. Forensic Sci Int Genet. 2016 Jan; 20:71-80.
Santos C, Phillips C, Fondevila M, Daniel R, van Oorschot RAH, Burchard EG, Schanfield MS, Souto L, Uacyisrael J, Via M, Carracedo Á, Lareu MV. PMID: 26517174.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Genetic and socioeconomic study of mate choice in Latinos reveals novel assortment patterns. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):13621-6.
Zou JY, Park DS, Burchard EG, Torgerson DG, Pino-Yanes M, Song YS, Sankararaman S, Halperin E, Zaitlen N. PMID: 26483472; PMCID: PMC4640764.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
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Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. Nat Genet. 2015 Dec; 47(12):1449-1456.
Paternoster L, Standl M, Waage J, Baurecht H, Hotze M, Strachan DP, Curtin JA, Bønnelykke K, Tian C, Takahashi A, Esparza-Gordillo J, Alves AC, Thyssen JP, den Dekker HT, Ferreira MA, Altmaier E, Sleiman PM, Xiao FL, Gonzalez JR, Marenholz I, Kalb B, Yanes MP, Xu CJ, Carstensen L, Groen-Blokhuis MM, Venturini C, Pennell CE, Barton SJ, Levin AM, Curjuric I, Bustamante M, Kreiner-Møller E, Lockett GA, Bacelis J, Bunyavanich S, Myers RA, Matanovic A, Kumar A, Tung JY, Hirota T, Kubo M, McArdle WL, Henderson AJ, Kemp JP, Zheng J, Smith GD, Rüschendorf F, Bauerfeind A, Lee-Kirsch MA, Arnold A, Homuth G, Schmidt CO, Mangold E, Cichon S, Keil T, Rodríguez E, Peters A, Franke A, Lieb W, Novak N, Fölster-Holst R, Horikoshi M, Pekkanen J, Sebert S, Husemoen LL, Grarup N, de Jongste JC, Rivadeneira F, Hofman A, Jaddoe VW, Pasmans SG, Elbert NJ, Uitterlinden AG, Marks GB, Thompson PJ, Matheson MC, Robertson CF, Australian Asthma Genetics Consortium (AAGC), Ried JS, Li J, Zuo XB, Zheng XD, Yin XY, Sun LD, McAleer MA, O'Regan GM, Fahy CM, Campbell LE, Macek M, Kurek M, Hu D, Eng C, Postma DS, Feenstra B, Geller F, Hottenga JJ, Middeldorp CM, Hysi P, Bataille V, Spector T, Tiesler CM, Thiering E, Pahukasahasram B, Yang JJ, Imboden M, Huntsman S, Vilor-Tejedor N, Relton CL, Myhre R, Nystad W, Custovic A, Weiss ST, Meyers DA, Söderhäll C, Melén E, Ober C, Raby BA, Simpson A, Jacobsson B, Holloway JW, Bisgaard H, Sunyer J, Hensch NMP, Williams LK, Godfrey KM, Wang CA, Boomsma DI, Melbye M, Koppelman GH, Jarvis D, McLean WI, Irvine AD, Zhang XJ, Hakonarson H, Gieger C, Burchard EG, Martin NG, Duijts L, Linneberg A, Jarvelin MR, Noethen MM, Lau S, Hübner N, Lee YA, Tamari M, Hinds DA, Glass D, Brown SJ, Heinrich J, Evans DM, Weidinger S. PMID: 26482879; PMCID: PMC4753676.
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PubMed Mentions:
264 Fields:
Translation:
HumansCells
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A Genome-Wide Association Study of Post-bronchodilator Lung Function in Children with Asthma. Am J Respir Crit Care Med. 2015 Sep 01; 192(5):634-7.
Brehm JM, Man Tse S, Croteau-Chonka DC, Forno E, Litonjua AA, Raby BA, Chen W, Yan Q, Boutaoui N, Acosta-Pérez E, Avila L, Weiss ST, Soto-Quiros M, Cloutier MM, Hu D, Pino-Yanes M, Wenzel SE, Spear ML, Kolls JK, Burchard EG, Canino G, Celedón JC. PMID: 26325155; PMCID: PMC4595689.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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CRISPR-Cas9-mediated gene knockout in primary human airway epithelial cells reveals a proinflammatory role for MUC18. Gene Ther. 2015 Oct; 22(10):822-9.
Chu HW, Rios C, Huang C, Wesolowska-Andersen A, Burchard EG, O'Connor BP, Fingerlin TE, Nichols D, Reynolds SD, Seibold MA. PMID: 26043872; PMCID: PMC4600011.
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PubMed Mentions:
58 Fields:
Translation:
HumansCells
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Stress and Bronchodilator Response in Children with Asthma. Am J Respir Crit Care Med. 2015 Jul 01; 192(1):47-56.
Brehm JM, Ramratnam SK, Tse SM, Croteau-Chonka DC, Pino-Yanes M, Rosas-Salazar C, Litonjua AA, Raby BA, Boutaoui N, Han YY, Chen W, Forno E, Marsland AL, Nugent NR, Eng C, Colón-Semidey A, Alvarez M, Acosta-Pérez E, Spear ML, Martinez FD, Avila L, Weiss ST, Soto-Quiros M, Ober C, Nicolae DL, Barnes KC, Lemanske RF, Strunk RC, Liu A, London SJ, Gilliland F, Sleiman P, March M, Hakonarson H, Duan QL, Kolls JK, Fritz GK, Hu D, Fani N, Stevens JS, Almli LM, Burchard EG, Shin J, McQuaid EL, Ressler K, Canino G, Celedón JC. PMID: 25918834; PMCID: PMC4511425.
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PubMed Mentions:
55 Fields:
Translation:
HumansCells
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Adapt-Mix: learning local genetic correlation structure improves summary statistics-based analyses. Bioinformatics. 2015 Jun 15; 31(12):i181-9.
Park DS, Brown B, Eng C, Huntsman S, Hu D, Torgerson DG, Burchard EG, Zaitlen N. PMID: 26072481; PMCID: PMC4553832.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Inferring parental genomic ancestries using pooled semi-Markov processes. Bioinformatics. 2015 Jun 15; 31(12):i190-6.
Zou JY, Halperin E, Burchard E, Sankararaman S. PMID: 26072482; PMCID: PMC4765873.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Obesity and bronchodilator response in black and Hispanic children and adolescents with asthma. Chest. 2015 Jun; 147(6):1591-1598.
McGarry ME, Castellanos E, Thakur N, Oh SS, Eng C, Davis A, Meade K, LeNoir MA, Avila PC, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Kumar R, Bibbins-Domingo K, Thyne SM, Sen S, Rodriguez-Santana JR, Borrell LN, Burchard EG. PMID: 25742612; PMCID: PMC4451713.
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PubMed Mentions:
47 Fields:
Translation:
Humans
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ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults. Clin Exp Allergy. 2015 Jun; 45(6):1051-9.
Vijverberg SJ, Koster ES, Tavendale R, Leusink M, Koenderman L, Raaijmakers JA, Postma DS, Koppelman GH, Turner SW, Mukhopadhyay S, Tse SM, Tantisira KG, Hawcutt DB, Francis B, Pirmohamed M, Pino-Yanes M, Eng C, Burchard EG, Palmer CN, Maitland-van der Zee AH. PMID: 25616159; PMCID: PMC4461653.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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The Hawaii clopidogrel lawsuit: the possible effect on clinical laboratory testing. Per Med. 2015 Jun; 12(3):179-181.
Wu AH, White MJ, Oh S, Burchard E. PMID: 29771642.
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PubMed Mentions:
16 Fields:
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Fine mapping of the myosin light chain kinase (MYLK) gene replicates the association with asthma in populations of Spanish descent. J Allergy Clin Immunol. 2015 Oct; 136(4):1116-8.e9.
Acosta-Herrera M, Pino-Yanes M, Ma SF, Barreto-Luis A, Corrales A, Cumplido J, Pérez-Rodríguez E, Campo P, Eng C, García-Robaina JC, Quintela I, Villar J, Blanca M, Carracedo Á, Carrillo T, Garcia JG, Torgerson DG, Burchard EG, Flores C. PMID: 26025125; PMCID: PMC4699578.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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The landscape of genomic imprinting across diverse adult human tissues. Genome Res. 2015 Jul; 25(7):927-36.
Baran Y, Subramaniam M, Biton A, Tukiainen T, Tsang EK, Rivas MA, Pirinen M, Gutierrez-Arcelus M, Smith KS, Kukurba KR, Zhang R, Eng C, Torgerson DG, Urbanek C, GTEx Consortium, Li JB, Rodriguez-Santana JR, Burchard EG, Seibold MA, MacArthur DG, Montgomery SB, Zaitlen NA, Lappalainen T. PMID: 25953952; PMCID: PMC4484390.
View in:
PubMed Mentions:
110 Fields:
Translation:
HumansCells
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PIGS: improved estimates of identity-by-descent probabilities by probabilistic IBD graph sampling. BMC Bioinformatics. 2015; 16 Suppl 5:S9.
Park DS, Baran Y, Hormozdiari F, Eng C, Torgerson DG, Burchard EG, Zaitlen N. PMID: 25860540; PMCID: PMC4402697.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Moving toward true inclusion of racial/ethnic minorities in federally funded studies. A key step for achieving respiratory health equality in the United States. Am J Respir Crit Care Med. 2015 Mar 01; 191(5):514-21.
Burchard EG, Oh SS, Foreman MG, Celedón JC. PMID: 25584658; PMCID: PMC4384771.
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PubMed Mentions:
52 Fields:
Translation:
Humans
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Association of a common genetic variant within ANKK1 with six-month cognitive performance after traumatic brain injury. Neurogenetics. 2015 Jul; 16(3):169-80.
Yue JK, Pronger AM, Ferguson AR, Temkin NR, Sharma S, Rosand J, Sorani MD, McAllister TW, Barber J, Winkler EA, Burchard EG, Hu D, Lingsma HF, Cooper SR, Puccio AM, Okonkwo DO, Diaz-Arrastia R, Manley GT, COBRIT Investigators, TRACK-TBI Investigators. PMID: 25633559; PMCID: PMC5588885.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma. Nat Commun. 2015 Jan 16; 6:5965.
Igartua C, Myers RA, Mathias RA, Pino-Yanes M, Eng C, Graves PE, Levin AM, Del-Rio-Navarro BE, Jackson DJ, Livne OE, Rafaels N, Edlund CK, Yang JJ, Huntsman S, Salam MT, Romieu I, Mourad R, Gern JE, Lemanske RF, Wyss A, Hoppin JA, Barnes KC, Burchard EG, Gauderman WJ, Martinez FD, Raby BA, Weiss ST, Williams LK, London SJ, Gilliland FD, Nicolae DL, Ober C. PMID: 25591454; PMCID: PMC4309441.
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PubMed Mentions:
43 Fields:
Translation:
Humans
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Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos. J Allergy Clin Immunol. 2015 Jun; 135(6):1502-10.
Pino-Yanes M, Gignoux CR, Galanter JM, Levin AM, Campbell CD, Eng C, Huntsman S, Nishimura KK, Gourraud PA, Mohajeri K, O'Roak BJ, Hu D, Mathias RA, Nguyen EA, Roth LA, Padhukasahasram B, Moreno-Estrada A, Sandoval K, Winkler CA, Lurmann F, Davis A, Farber HJ, Meade K, Avila PC, Serebrisky D, Chapela R, Ford JG, Lenoir MA, Thyne SM, Brigino-Buenaventura E, Borrell LN, Rodriguez-Cintron W, Sen S, Kumar R, Rodriguez-Santana JR, Bustamante CD, Martinez FD, Raby BA, Weiss ST, Nicolae DL, Ober C, Meyers DA, Bleecker ER, Mack SJ, Hernandez RD, Eichler EE, Barnes KC, Williams LK, Torgerson DG, Burchard EG. PMID: 25488688; PMCID: PMC4458233.
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PubMed Mentions:
29 Fields:
Translation:
HumansCells
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A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults. Blood. 2015 Jan 22; 125(4):680-6.
Perez-Andreu V, Roberts KG, Xu H, Smith C, Zhang H, Yang W, Harvey RC, Payne-Turner D, Devidas M, Cheng IM, Carroll WL, Heerema NA, Carroll AJ, Raetz EA, Gastier-Foster JM, Marcucci G, Bloomfield CD, Mrózek K, Kohlschmidt J, Stock W, Kornblau SM, Konopleva M, Paietta E, Rowe JM, Luger SM, Tallman MS, Dean M, Burchard EG, Torgerson DG, Yue F, Wang Y, Pui CH, Jeha S, Relling MV, Evans WE, Gerhard DS, Loh ML, Willman CL, Hunger SP, Mullighan CG, Yang JJ. PMID: 25468567; PMCID: PMC4304112.
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PubMed Mentions:
58 Fields:
Translation:
HumansCells
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Telomere length and the risk of atrial fibrillation: insights into the role of biological versus chronological aging. Circ Arrhythm Electrophysiol. 2014 Dec; 7(6):1026-32.
Roberts JD, Dewland TA, Longoria J, Fitzpatrick AL, Ziv E, Hu D, Lin J, Glidden DV, Psaty BM, Burchard EG, Blackburn EH, Olgin JE, Heckbert SR, Marcus GM. PMID: 25381796; PMCID: PMC4294941.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Genetic ancestry influences asthma susceptibility and lung function among Latinos. J Allergy Clin Immunol. 2015 Jan; 135(1):228-35.
Pino-Yanes M, Thakur N, Gignoux CR, Galanter JM, Roth LA, Eng C, Nishimura KK, Oh SS, Vora H, Huntsman S, Nguyen EA, Hu D, Drake KA, Conti DV, Moreno-Estrada A, Sandoval K, Winkler CA, Borrell LN, Lurmann F, Islam TS, Davis A, Farber HJ, Meade K, Avila PC, Serebrisky D, Bibbins-Domingo K, Lenoir MA, Ford JG, Brigino-Buenaventura E, Rodriguez-Cintron W, Thyne SM, Sen S, Rodriguez-Santana JR, Bustamante CD, Williams LK, Gilliland FD, Gauderman WJ, Kumar R, Torgerson DG, Burchard EG. PMID: 25301036; PMCID: PMC4289103.
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PubMed Mentions:
81 Fields:
Translation:
Humans
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Medical research: Missing patients. Nature. 2014 Sep 18; 513(7518):301-2.
Burchard EG. PMID: 25230631.
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PubMed Mentions:
27 Fields:
Translation:
Humans
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Whole-genome sequencing of individuals from a founder population identifies candidate genes for asthma. PLoS One. 2014; 9(8):e104396.
Campbell CD, Mohajeri K, Malig M, Hormozdiari F, Nelson B, Du G, Patterson KM, Eng C, Torgerson DG, Hu D, Herman C, Chong JX, Ko A, O'Roak BJ, Krumm N, Vives L, Lee C, Roth LA, Rodriguez-Cintron W, Rodriguez-Santana J, Brigino-Buenaventura E, Davis A, Meade K, LeNoir MA, Thyne S, Jackson DJ, Gern JE, Lemanske RF, Shendure J, Abney M, Burchard EG, Ober C, Eichler EE. PMID: 25116239; PMCID: PMC4130548.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis. BMC Med Genomics. 2014 Aug 02; 7:48.
Bunyavanich S, Schadt EE, Himes BE, Lasky-Su J, Qiu W, Lazarus R, Ziniti JP, Cohain A, Linderman M, Torgerson DG, Eng CS, Pino-Yanes M, Padhukasahasram B, Yang JJ, Mathias RA, Beaty TH, Li X, Graves P, Romieu I, Navarro Bdel R, Salam MT, Vora H, Nicolae DL, Ober C, Martinez FD, Bleecker ER, Meyers DA, Gauderman WJ, Gilliland F, Burchard EG, Barnes KC, Williams LK, London SJ, Zhang B, Raby BA, Weiss ST. PMID: 25085501; PMCID: PMC4127082.
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PubMed Mentions:
32 Fields:
Translation:
HumansCells
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Nocturnal asthma and the importance of race/ethnicity and genetic ancestry. Am J Respir Crit Care Med. 2014 Aug 01; 190(3):266-73.
Levin AM, Wang Y, Wells KE, Padhukasahasram B, Yang JJ, Burchard EG, Williams LK. PMID: 24937318; PMCID: PMC4226040.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Genome-wide association analysis identifies six new loci associated with forced vital capacity. Nat Genet. 2014 Jul; 46(7):669-77.
Loth DW, Soler Artigas M, Gharib SA, Wain LV, Franceschini N, Koch B, Pottinger TD, Smith AV, Duan Q, Oldmeadow C, Lee MK, Strachan DP, James AL, Huffman JE, Vitart V, Ramasamy A, Wareham NJ, Kaprio J, Wang XQ, Trochet H, Kähönen M, Flexeder C, Albrecht E, Lopez LM, de Jong K, Thyagarajan B, Alves AC, Enroth S, Omenaas E, Joshi PK, Fall T, Viñuela A, Launer LJ, Loehr LR, Fornage M, Li G, Wilk JB, Tang W, Manichaikul A, Lahousse L, Harris TB, North KE, Rudnicka AR, Hui J, Gu X, Lumley T, Wright AF, Hastie ND, Campbell S, Kumar R, Pin I, Scott RA, Pietiläinen KH, Surakka I, Liu Y, Holliday EG, Schulz H, Heinrich J, Davies G, Vonk JM, Wojczynski M, Pouta A, Johansson A, Wild SH, Ingelsson E, Rivadeneira F, Völzke H, Hysi PG, Eiriksdottir G, Morrison AC, Rotter JI, Gao W, Postma DS, White WB, Rich SS, Hofman A, Aspelund T, Couper D, Smith LJ, Psaty BM, Lohman K, Burchard EG, Uitterlinden AG, Garcia M, Joubert BR, McArdle WL, Musk AB, Hansel N, Heckbert SR, Zgaga L, van Meurs JB, Navarro P, Rudan I, Oh YM, Redline S, Jarvis DL, Zhao JH, Rantanen T, O'Connor GT, Ripatti S, Scott RJ, Karrasch S, Grallert H, Gaddis NC, Starr JM, Wijmenga C, Minster RL, Lederer DJ, Pekkanen J, Gyllensten U, Campbell H, Morris AP, Gläser S, Hammond CJ, Burkart KM, Beilby J, Kritchevsky SB, Gudnason V, Hancock DB, Williams OD, Polasek O, Zemunik T, Kolcic I, Petrini MF, Wjst M, Kim WJ, Porteous DJ, Scotland G, Smith BH, Viljanen A, Heliövaara M, Attia JR, Sayers I, Hampel R, Gieger C, Deary IJ, Boezen HM, Newman A, Jarvelin MR, Wilson JF, Lind L, Stricker BH, Teumer A, Spector TD, Melén E, Peters MJ, Lange LA, Barr RG, Bracke KR, Verhamme FM, Sung J, Hiemstra PS, Cassano PA, Sood A, Hayward C, Dupuis J, Hall IP, Brusselle GG, Tobin MD, London SJ. PMID: 24929828; PMCID: PMC4140093.
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PubMed Mentions:
76 Fields:
Translation:
Humans
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Human genetics. The genetics of Mexico recapitulates Native American substructure and affects biomedical traits. Science. 2014 Jun 13; 344(6189):1280-5.
Moreno-Estrada A, Gignoux CR, Fernández-López JC, Zakharia F, Sikora M, Contreras AV, Acuña-Alonzo V, Sandoval K, Eng C, Romero-Hidalgo S, Ortiz-Tello P, Robles V, Kenny EE, Nuño-Arana I, Barquera-Lozano R, Macín-Pérez G, Granados-Arriola J, Huntsman S, Galanter JM, Via M, Ford JG, Chapela R, Rodriguez-Cintron W, Rodríguez-Santana JR, Romieu I, Sienra-Monge JJ, del Rio Navarro B, London SJ, Ruiz-Linares A, Garcia-Herrera R, Estrada K, Hidalgo-Miranda A, Jimenez-Sanchez G, Carnevale A, Soberón X, Canizales-Quinteros S, Rangel-Villalobos H, Silva-Zolezzi I, Burchard EG, Bustamante CD. PMID: 24926019; PMCID: PMC4156478.
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PubMed Mentions:
196 Fields:
Translation:
Humans
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Socioeconomic status and asthma control in African American youth in SAGE II. J Asthma. 2014 Sep; 51(7):720-8.
Thakur N, Martin M, Castellanos E, Oh SS, Roth LA, Eng C, Brigino-Buenaventura E, Davis A, Meade K, LeNoir MA, Farber HJ, Thyne S, Sen S, Bibbins-Domingo K, Borrell LN, Burchard EG. PMID: 24654704; PMCID: PMC4257058.
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PubMed Mentions:
23 Fields:
Translation:
HumansPHPublic Health
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Genome-wide interaction studies reveal sex-specific asthma risk alleles. Hum Mol Genet. 2014 Oct 01; 23(19):5251-9.
Myers RA, Scott NM, Gauderman WJ, Qiu W, Mathias RA, Romieu I, Levin AM, Pino-Yanes M, Graves PE, Villarreal AB, Beaty TH, Carey VJ, Croteau-Chonka DC, del Rio Navarro B, Edlund C, Hernandez-Cadena L, Navarro-Olivos E, Padhukasahasram B, Salam MT, Torgerson DG, Van den Berg DJ, Vora H, Bleecker ER, Meyers DA, Williams LK, Martinez FD, Burchard EG, Barnes KC, Gilliland FD, Weiss ST, London SJ, Raby BA, Ober C, Nicolae DL, GRAAD. PMID: 24824216; PMCID: PMC4159149.
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PubMed Mentions:
41 Fields:
Translation:
Humans
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The lung corps' approach to reducing health disparities in respiratory disease. Ann Am Thorac Soc. 2014 May; 11(4):655-60.
Thakur N, McGarry ME, Oh SS, Galanter JM, Finn PW, Burchard EG, ATS Health Equality Committee. PMID: 24697756; PMCID: PMC4225795.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease. J Allergy Clin Immunol. 2014 Mar; 133(3):670-8.e12.
Poole A, Urbanek C, Eng C, Schageman J, Jacobson S, O'Connor BP, Galanter JM, Gignoux CR, Roth LA, Kumar R, Lutz S, Liu AH, Fingerlin TE, Setterquist RA, Burchard EG, Rodriguez-Santana J, Seibold MA. PMID: 24495433; PMCID: PMC4043390.
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PubMed Mentions:
125 Fields:
Translation:
HumansCells
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A genome-wide association study of bronchodilator response in Latinos implicates rare variants. J Allergy Clin Immunol. 2014; 133(2):370-378. e15.
Drake KA, Torgerson DG, Gignoux CR, Galanter JM, Roth LA, Huntsman S, Eng C, Oh SS, Yee SW, Lin L, Bustamante CD, Moreno-Estrada A, Sandoval K, Davis A, Borrell LN, Farber HJ, Kumar R, Avila PC, Brigino-Buenaventura E, Chapela R, Ford JG, Lenoir MA, Lurmann F, Meade K, Serebrisky D, Thyne S, Rodríguez-Cintrón W, Sen S, Rodríguez-Santana JR, Hernandez RD, Giacomini KM, Burchard EG. View Publication.
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Gene-based association identifies SPATA13-AS1 as a pharmacogenomic predictor of inhaled short-acting beta-agonist response in multiple population groups. Pharmacogenomics J. 2014 Aug; 14(4):365-71.
Padhukasahasram B, Yang JJ, Levin AM, Yang M, Burchard EG, Kumar R, Kwok PY, Seibold MA, Lanfear DE, Williams LK. PMID: 24418963; PMCID: PMC4098013.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study. J Allergy Clin Immunol. 2014 Aug; 134(2):295-305.
Galanter JM, Gignoux CR, Torgerson DG, Roth LA, Eng C, Oh SS, Nguyen EA, Drake KA, Huntsman S, Hu D, Sen S, Davis A, Farber HJ, Avila PC, Brigino-Buenaventura E, LeNoir MA, Meade K, Serebrisky D, Borrell LN, Rodríguez-Cintrón W, Estrada AM, Mendoza KS, Winkler CA, Klitz W, Romieu I, London SJ, Gilliland F, Martinez F, Bustamante C, Williams LK, Kumar R, Rodríguez-Santana JR, Burchard EG. PMID: 24406073; PMCID: PMC4085159.
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PubMed Mentions:
63 Fields:
Translation:
HumansCells
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Genome-wide association study of lung function phenotypes in a founder population. J Allergy Clin Immunol. 2014; 133(1):248-55.e1-10.
Yao TC, Du G, Han L, Sun Y, Hu D, Yang JJ, Mathias R, Roth LA, Rafaels N, Thompson EE, Loisel DA, Anderson R, Eng C, Arruabarrena Orbegozo M, Young M, Klocksieben JM, Anderson E, Shanovich K, Lester LA, Williams LK, Barnes KC, Burchard EG, Nicolae DL, Abney M, Ober C. View Publication.
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Reconstructing Native American migrations from whole-genome and whole-exome data. PLoS Genet. 2013; 9(12):e1004023.
Gravel S, Zakharia F, Moreno-Estrada A, Byrnes JK, Muzzio M, Rodriguez-Flores JL, Kenny EE, Gignoux CR, Maples BK, Guiblet W, Dutil J, Via M, Sandoval K, Bedoya G, 1000 Genomes Project, Oleksyk TK, Ruiz-Linares A, Burchard EG, Martinez-Cruzado JC, Bustamante CD. PMID: 24385924; PMCID: PMC3873240.
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PubMed Mentions:
92 Fields:
Translation:
Humans
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Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse. Nat Genet. 2013; 45(12):1494-8.
Perez-Andreu V, Roberts KG, Harvey RC, Yang W, Cheng C, Pei D, Xu H, Gastier-Foster J, E S, Lim JY, Chen IM, Fan Y, Devidas M, Borowitz MJ, Smith C, Neale G, Burchard EG, Torgerson DG, Klussmann FA, Villagran CR, Winick NJ, Camitta BM, Raetz E, Wood B, Yue F, Carroll WL, Larsen E, Bowman WP, Loh ML, Dean M, Bhojwani D, Pui CH, Evans WE, Relling MV, Hunger SP, Willman CL, Mullighan CG, Yang JJ. View Publication.
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Socioeconomic status and childhood asthma in urban minority youths. The GALA II and SAGE II studies. Am J Respir Crit Care Med. 2013 Nov 15; 188(10):1202-9.
Thakur N, Oh SS, Nguyen EA, Martin M, Roth LA, Galanter J, Gignoux CR, Eng C, Davis A, Meade K, LeNoir MA, Avila PC, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Kumar R, Williams LK, Bibbins-Domingo K, Thyne S, Sen S, Rodriguez-Santana JR, Borrell LN, Burchard EG. PMID: 24050698; PMCID: PMC3863734.
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PubMed Mentions:
65 Fields:
Translation:
Humans
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Reconstructing the population genetic history of the Caribbean. PLoS Genet. 2013 Nov; 9(11):e1003925.
Moreno-Estrada A, Gravel S, Zakharia F, McCauley JL, Byrnes JK, Gignoux CR, Ortiz-Tello PA, Martínez RJ, Hedges DJ, Morris RW, Eng C, Sandoval K, Acevedo-Acevedo S, Norman PJ, Layrisse Z, Parham P, Martínez-Cruzado JC, Burchard EG, Cuccaro ML, Martin ER, Bustamante CD. PMID: 24244192; PMCID: PMC3828151.
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PubMed Mentions:
166 Fields:
Translation:
Humans
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Early-life air pollution and asthma risk in minority children. The GALA II and SAGE II studies. Am J Respir Crit Care Med. 2013 Aug 01; 188(3):309-18.
Nishimura KK, Galanter JM, Roth LA, Oh SS, Thakur N, Nguyen EA, Thyne S, Farber HJ, Serebrisky D, Kumar R, Brigino-Buenaventura E, Davis A, LeNoir MA, Meade K, Rodriguez-Cintron W, Avila PC, Borrell LN, Bibbins-Domingo K, Rodriguez-Santana JR, Sen S, Lurmann F, Balmes JR, Burchard EG. PMID: 23750510; PMCID: PMC3778732.
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PubMed Mentions:
131 Fields:
Translation:
HumansPHPublic Health
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Factors associated with degree of atopy in Latino children in a nationwide pediatric sample: the Genes-environments and Admixture in Latino Asthmatics (GALA II) study. J Allergy Clin Immunol. 2013 Oct; 132(4):896-905.e1.
Kumar R, Nguyen EA, Roth LA, Oh SS, Gignoux CR, Huntsman S, Eng C, Moreno-Estrada A, Sandoval K, Peñaloza-Espinosa RI, López-López M, Avila PC, Farber HJ, Tcheurekdjian H, Rodriguez-Cintron W, Rodriguez-Santana JR, Serebrisky D, Thyne SM, Williams LK, Winkler C, Bustamante CD, Pérez-Stable EJ, Borrell LN, Burchard EG. PMID: 23684070; PMCID: PMC3788073.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation. Bioinformatics. 2013 Jun 01; 29(11):1407-15.
Pasaniuc B, Sankararaman S, Torgerson DG, Gignoux C, Zaitlen N, Eng C, Rodriguez-Cintron W, Chapela R, Ford JG, Avila PC, Rodriguez-Santana J, Chen GK, Le Marchand L, Henderson B, Reich D, Haiman CA, Gonzàlez Burchard E, Halperin E. PMID: 23572411; PMCID: PMC3661056.
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PubMed Mentions:
30 Fields:
Translation:
Humans
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Childhood obesity and asthma control in the GALA II and SAGE II studies. Am J Respir Crit Care Med. 2013 Apr 01; 187(7):697-702.
Borrell LN, Nguyen EA, Roth LA, Oh SS, Tcheurekdjian H, Sen S, Davis A, Farber HJ, Avila PC, Brigino-Buenaventura E, Lenoir MA, Lurmann F, Meade K, Serebrisky D, Rodriguez-Cintron W, Kumar R, Rodriguez-Santana JR, Thyne SM, Burchard EG. PMID: 23392439; PMCID: PMC3678111.
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PubMed Mentions:
70 Fields:
Translation:
HumansPHPublic Health
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Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations. J Natl Cancer Inst. 2013 May 15; 105(10):733-42.
Xu H, Yang W, Perez-Andreu V, Devidas M, Fan Y, Cheng C, Pei D, Scheet P, Burchard EG, Eng C, Huntsman S, Torgerson DG, Dean M, Winick NJ, Martin PL, Camitta BM, Bowman WP, Willman CL, Carroll WL, Mullighan CG, Bhojwani D, Hunger SP, Pui CH, Evans WE, Relling MV, Loh ML, Yang JJ. PMID: 23512250; PMCID: PMC3691938.
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PubMed Mentions:
129 Fields:
Translation:
HumansCells
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Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene. PLoS One. 2013; 8(2):e56179.
Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Lima JJ, Irvin CG, Peters SP, Kubo M, Tamari M, Nakamura Y, Litonjua AA, Tantisira KG, Raby BA, Bleecker ER, Meyers DA, London SJ, Barnes KC, Gilliland FD, Williams LK, Burchard EG, Nicolae DL, Ober C, DeMeo DL, Silverman EK, Paigen B, Churchill G, Shapiro SD, Weiss ST. PMID: 23457522; PMCID: PMC3572953.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations. J Allergy Clin Immunol. 2013 Apr; 131(4):1176-84.
Levin AM, Mathias RA, Huang L, Roth LA, Daley D, Myers RA, Himes BE, Romieu I, Yang M, Eng C, Park JE, Zoratti K, Gignoux CR, Torgerson DG, Galanter JM, Huntsman S, Nguyen EA, Becker AB, Chan-Yeung M, Kozyrskyj AL, Kwok PY, Gilliland FD, Gauderman WJ, Bleecker ER, Raby BA, Meyers DA, London SJ, Martinez FD, Weiss ST, Burchard EG, Nicolae DL, Ober C, Barnes KC, Williams LK. PMID: 23146381; PMCID: PMC3596497.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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An integrated map of genetic variation from 1,092 human genomes. Nature. 2012 Nov 01; 491(7422):56-65.
1000 Genomes Project Consortium, Abecasis GR, Auton A, Brooks LD, DePristo MA, Durbin RM, Handsaker RE, Kang HM, Marth GT, McVean GA. PMID: 23128226; PMCID: PMC3498066.
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PubMed Mentions:
4390 Fields:
Translation:
HumansCells
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Genetic ancestry and its association with asthma exacerbations among African American subjects with asthma. J Allergy Clin Immunol. 2012 Dec; 130(6):1302-6.
Rumpel JA, Ahmedani BK, Peterson EL, Wells KE, Yang M, Levin AM, Yang JJ, Kumar R, Burchard EG, Williams LK. PMID: 23069492; PMCID: PMC3511609.
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PubMed Mentions:
33 Fields:
Translation:
Humans
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Population genetic inference from personal genome data: impact of ancestry and admixture on human genomic variation. Am J Hum Genet. 2012 Oct 05; 91(4):660-71.
Kidd JM, Gravel S, Byrnes J, Moreno-Estrada A, Musharoff S, Bryc K, Degenhardt JD, Brisbin A, Sheth V, Chen R, McLaughlin SF, Peckham HE, Omberg L, Bormann Chung CA, Stanley S, Pearlstein K, Levandowsky E, Acevedo-Acevedo S, Auton A, Keinan A, Acuña-Alonzo V, Barquera-Lozano R, Canizales-Quinteros S, Eng C, Burchard EG, Russell A, Reynolds A, Clark AG, Reese MG, Lincoln SE, Butte AJ, De La Vega FM, Bustamante CD. PMID: 23040495; PMCID: PMC3484644.
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PubMed Mentions:
61 Fields:
Translation:
Humans
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Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans. J Allergy Clin Immunol. 2012 Dec; 130(6):1294-301.
Myers RA, Himes BE, Gignoux CR, Yang JJ, Gauderman WJ, Rebordosa C, Xie J, Torgerson DG, Levin AM, Baurley J, Graves PE, Mathias RA, Romieu I, Roth LA, Conti D, Avila L, Eng C, Vora H, LeNoir MA, Soto-Quiros M, Liu J, Celedón JC, Galanter JM, Farber HJ, Kumar R, Avila PC, Meade K, Serebrisky D, Thyne S, Rodriguez-Cintron W, Rodriguez-Santana JR, Borrell LN, Lemanske RF, Bleecker ER, Meyers DA, London SJ, Barnes KC, Raby BA, Martinez FD, Gilliland FD, Williams LK, Burchard EG, Weiss ST, Nicolae DL, Ober C. PMID: 23040885; PMCID: PMC3666859.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Asthma Research for All of the United States. Pediatr Allergy Immunol Pulmonol. 2012 Sep; 25(3):128-131.
Nguyen EA, Burchard EG. PMID: 22970422; PMCID: PMC3429272.
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PubMed Mentions:
2 Fields:
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Genetic variation in B cell-activating factor of the TNF family (BAFF) and asthma exacerbations among African American subjects. J Allergy Clin Immunol. 2012 Oct; 130(4):996-9.e6.
Kumar R, Williams LK, Kato A, Peterson EL, Favoreto S, Hulse K, Wang D, Beckman K, Thyne S, LeNoir M, Meade K, Lanfear DE, Levin AM, Favro D, Yang JJ, Weiss K, Boushey HA, Grammer L, Avila PC, Burchard EG, Schleimer R. PMID: 22728080; PMCID: PMC3520130.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Genetic ancestry-smoking interactions and lung function in African Americans: a cohort study. PLoS One. 2012; 7(6):e39541.
Aldrich MC, Kumar R, Colangelo LA, Williams LK, Sen S, Kritchevsky SB, Meibohm B, Galanter J, Hu D, Gignoux CR, Liu Y, Harris TB, Ziv E, Zmuda J, Garcia M, Leak TS, Foreman MG, Smith LJ, Fornage M, Liu K, Burchard EG, Health ABC and CARDIA Studies Groups. PMID: 22737244; PMCID: PMC3380861.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects. J Allergy Clin Immunol. 2012 Sep; 130(3):622-629.e9.
Torgerson DG, Capurso D, Ampleford EJ, Li X, Moore WC, Gignoux CR, Hu D, Eng C, Mathias RA, Busse WW, Castro M, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Teague WG, Wenzel SE, Rodríguez-Santana JR, Rodríguez-Cintrón W, Avila PC, Ford JG, Barnes KC, Burchard EG, Howard TD, Bleecker ER, Meyers DA, Cox NJ, Ober C, Nicolae DL. PMID: 22607992; PMCID: PMC3503456.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Melanesian blond hair is caused by an amino acid change in TYRP1. Science. 2012 May 04; 336(6081):554.
Kenny EE, Timpson NJ, Sikora M, Yee MC, Moreno-Estrada A, Eng C, Huntsman S, Burchard EG, Stoneking M, Bustamante CD, Myles S. PMID: 22556244; PMCID: PMC3481182.
View in:
PubMed Mentions:
39 Fields:
Translation:
Humans
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Effect of secondhand smoke on asthma control among black and Latino children. J Allergy Clin Immunol. 2012 Jun; 129(6):1478-83.e7.
Oh SS, Tcheurekdjian H, Roth LA, Nguyen EA, Sen S, Galanter JM, Davis A, Farber HJ, Gilliland FD, Kumar R, Avila PC, Brigino-Buenaventura E, Chapela R, Ford JG, LeNoir MA, Lurmann F, Meade K, Serebrisky D, Thyne S, Rodriguez-Cintron W, Rodriguez-Santana JR, Williams LK, Borrell LN, Burchard EG. PMID: 22552109; PMCID: PMC3367092.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansPHPublic Health
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Case-control admixture mapping in Latino populations enriches for known asthma-associated genes. J Allergy Clin Immunol. 2012 Jul; 130(1):76-82.e12.
Torgerson DG, Gignoux CR, Galanter JM, Drake KA, Roth LA, Eng C, Huntsman S, Torres R, Avila PC, Chapela R, Ford JG, Rodríguez-Santana JR, Rodríguez-Cintrón W, Hernandez RD, Burchard EG. PMID: 22502797; PMCID: PMC3593143.
View in:
PubMed Mentions:
32 Fields:
Translation:
Humans
-
Fast and accurate inference of local ancestry in Latino populations. Bioinformatics. 2012 May 15; 28(10):1359-67.
Baran Y, Pasaniuc B, Sankararaman S, Torgerson DG, Gignoux C, Eng C, Rodriguez-Cintron W, Chapela R, Ford JG, Avila PC, Rodriguez-Santana J, Burchard EG, Halperin E. PMID: 22495753; PMCID: PMC3348558.
View in:
PubMed Mentions:
148 Fields:
Translation:
Humans
-
Heterogeneity in genetic admixture across different regions of Argentina. PLoS One. 2012; 7(4):e34695.
Avena S, Via M, Ziv E, Pérez-Stable EJ, Gignoux CR, Dejean C, Huntsman S, Torres-Mejía G, Dutil J, Matta JL, Beckman K, Burchard EG, Parolin ML, Goicoechea A, Acreche N, Boquet M, Ríos Part Mdel C, Fernández V, Rey J, Stern MC, Carnese RF, Fejerman L. PMID: 22506044; PMCID: PMC3323559.
View in:
PubMed Mentions:
54 Fields:
Translation:
Humans
-
Development of a panel of genome-wide ancestry informative markers to study admixture throughout the Americas. PLoS Genet. 2012; 8(3):e1002554.
Galanter JM, Fernandez-Lopez JC, Gignoux CR, Barnholtz-Sloan J, Fernandez-Rozadilla C, Via M, Hidalgo-Miranda A, Contreras AV, Figueroa LU, Raska P, Jimenez-Sanchez G, Zolezzi IS, Torres M, Ponte CR, Ruiz Y, Salas A, Nguyen E, Eng C, Borjas L, Zabala W, Barreto G, González FR, Ibarra A, Taboada P, Porras L, Moreno F, Bigham A, Gutierrez G, Brutsaert T, León-Velarde F, Moore LG, Vargas E, Cruz M, Escobedo J, Rodriguez-Santana J, Rodriguez-Cintrón W, Chapela R, Ford JG, Bustamante C, Seminara D, Shriver M, Ziv E, Burchard EG, Haile R, Parra E, Carracedo A, LACE Consortium. PMID: 22412386; PMCID: PMC3297575.
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PubMed Mentions:
99 Fields:
Translation:
Humans
-
African ancestry, early life exposures, and respiratory morbidity in early childhood. Clin Exp Allergy. 2012; 42(2):265-74.
Kumar R, Tsai HJ, Hong X, Gignoux C, Pearson C, Ortiz K, Fu M, Pongracic JA,
Burchard EG, Bauchner H, Wang X. View Publication.
-
ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia. J Clin Oncol. 2012 Mar 01; 30(7):751-7.
Xu H, Cheng C, Devidas M, Pei D, Fan Y, Yang W, Neale G, Scheet P, Burchard EG, Torgerson DG, Eng C, Dean M, Antillon F, Winick NJ, Martin PL, Willman CL, Camitta BM, Reaman GH, Carroll WL, Loh M, Evans WE, Pui CH, Hunger SP, Relling MV, Yang JJ. PMID: 22291082; PMCID: PMC3295551.
View in:
PubMed Mentions:
83 Fields:
Translation:
Humans
-
Admixture mapping identifies a locus on 6q25 associated with breast cancer risk in US Latinas. Hum Mol Genet. 2012 Apr 15; 21(8):1907-17.
Fejerman L, Chen GK, Eng C, Huntsman S, Hu D, Williams A, Pasaniuc B, John EM, Via M, Gignoux C, Ingles S, Monroe KR, Kolonel LN, Torres-Mejía G, Pérez-Stable EJ, Burchard EG, Henderson BE, Haiman CA, Ziv E. PMID: 22228098; PMCID: PMC3313799.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Genetic association between human chitinases and lung function in COPD. Hum Genet. 2012 Jul; 131(7):1105-14.
Aminuddin F, Akhabir L, Stefanowicz D, Paré PD, Connett JE, Anthonisen NR, Fahy JV, Seibold MA, Burchard EG, Eng C, Gulsvik A, Bakke P, Cho MH, Litonjua A, Lomas DA, Anderson WH, Beaty TH, Crapo JD, Silverman EK, Sandford AJ. PMID: 22200767; PMCID: PMC3771523.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Polymorphism in Osteopontin Gene (SPP1) Is Associated with Asthma and Related Phenotypes in a Puerto Rican Population. Pediatr Allergy Immunol Pulmonol. 2011 Dec; 24(4):207-214.
Arjomandi M, Galanter JM, Choudhry S, Eng C, Hu D, Beckman K, Chapela R, Rodríguez-Santana JR, Rodríguez-Cintrón W, Ford J, Avila PC, Burchard EG. PMID: 22276228; PMCID: PMC3255512.
View in:
PubMed Mentions:
10 Fields:
-
Quantifying the proportion of severe asthma exacerbations attributable to inhaled corticosteroid nonadherence. J Allergy Clin Immunol. 2011 Dec; 128(6):1185-1191.e2.
Williams LK, Peterson EL, Wells K, Ahmedani BK, Kumar R, Burchard EG, Chowdhry VK, Favro D, Lanfear DE, Pladevall M. PMID: 22019090; PMCID: PMC3229671.
View in:
PubMed Mentions:
127 Fields:
Translation:
Humans
-
Identification of KIF3A as a novel candidate gene for childhood asthma using RNA expression and population allelic frequencies differences. PLoS One. 2011; 6(8):e23714.
Kovacic MB, Myers JM, Wang N, Martin LJ, Lindsey M, Ericksen MB, He H, Patterson TL, Baye TM, Torgerson D, Roth LA, Gupta J, Sivaprasad U, Gibson AM, Tsoras AM, Hu D, Eng C, Chapela R, Rodríguez-Santana JR, Rodríguez-Cintrón W, Avila PC, Beckman K, Seibold MA, Gignoux C, Musaad SM, Chen W, Burchard EG, Hershey GK. PMID: 21912604; PMCID: PMC3166061.
View in:
PubMed Mentions:
36 Fields:
Translation:
Humans
-
Ethnic variability in persistent asthma after in utero tobacco exposure. Pediatrics. 2011 Sep; 128(3):e623-30.
Akuete K, Oh SS, Thyne S, Rodriguez-Santana JR, Chapela R, Meade K, Rodriguez-Cintron W, LeNoir M, Ford JG, Williams LK, Avila PC, Burchard EG, Tcheurekdjian H. PMID: 21859918; PMCID: PMC3164096.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansPHPublic Health
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Furthering the link between the sarcomere and primary cardiomyopathies: restrictive cardiomyopathy associated with multiple mutations in genes previously associated with hypertrophic or dilated cardiomyopathy. Am J Med Genet A. 2011 Sep; 155A(9):2229-35.
Caleshu C, Sakhuja R, Nussbaum RL, Schiller NB, Ursell PC, Eng C, De Marco T, McGlothlin D, Burchard EG, Rame JE. PMID: 21823217; PMCID: PMC3158811.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet. 2011 Jul 31; 43(9):887-92.
Torgerson DG, Ampleford EJ, Chiu GY, Gauderman WJ, Gignoux CR, Graves PE, Himes BE, Levin AM, Mathias RA, Hancock DB, Baurley JW, Eng C, Stern DA, Celedón JC, Rafaels N, Capurso D, Conti DV, Roth LA, Soto-Quiros M, Togias A, Li X, Myers RA, Romieu I, Van Den Berg DJ, Hu D, Hansel NN, Hernandez RD, Israel E, Salam MT, Galanter J, Avila PC, Avila L, Rodriquez-Santana JR, Chapela R, Rodriguez-Cintron W, Diette GB, Adkinson NF, Abel RA, Ross KD, Shi M, Faruque MU, Dunston GM, Watson HR, Mantese VJ, Ezurum SC, Liang L, Ruczinski I, Ford JG, Huntsman S, Chung KF, Vora H, Li X, Calhoun WJ, Castro M, Sienra-Monge JJ, del Rio-Navarro B, Deichmann KA, Heinzmann A, Wenzel SE, Busse WW, Gern JE, Lemanske RF, Beaty TH, Bleecker ER, Raby BA, Meyers DA, London SJ, Mexico City Childhood Asthma Study (MCAAS), Gilliland FD, Children's Health Study (CHS) and HARBORS study, Burchard EG, Genetics of Asthma in Latino Americans (GALA) Study, Study of Genes-Environment and Admixture in Lat, Martinez FD, Childhood Asthma Research and Education (CARE) Network, Weiss ST, Childhood Asthma Management Program (CAMP), Williams LK, Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-Ethnicity (SAPPHIRE), Barnes KC, Genetic Research on Asthma in African Diaspora (GRAAD) Study, Ober C, Nicolae DL. PMID: 21804549; PMCID: PMC3445408.
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PubMed Mentions:
409 Fields:
Translation:
Humans
-
Genomics for the world. Nature. 2011 Jul 13; 475(7355):163-5.
Bustamante CD, Burchard EG, De la Vega FM. PMID: 21753830; PMCID: PMC3708540.
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PubMed Mentions:
300 Fields:
Translation:
Humans
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Identification of ATPAF1 as a novel candidate gene for asthma in children. J Allergy Clin Immunol. 2011 Oct; 128(4):753-760.e11.
Schauberger EM, Ewart SL, Arshad SH, Huebner M, Karmaus W, Holloway JW, Friderici KH, Ziegler JT, Zhang H, Rose-Zerilli MJ, Barton SJ, Holgate ST, Kilpatrick JR, Harley JB, Lajoie-Kadoch S, Harley IT, Hamid Q, Kurukulaaratchy RJ, Seibold MA, Avila PC, Rodriguez-Cintrón W, Rodriguez-Santana JR, Hu D, Gignoux C, Romieu I, London SJ, Burchard EG, Langefeld CD, Wills-Karp M. PMID: 21696813; PMCID: PMC3185108.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCTClinical Trials
-
Cosmopolitan and ethnic-specific replication of genetic risk factors for asthma in 2 Latino populations. J Allergy Clin Immunol. 2011 Jul; 128(1):37-43.e12.
Galanter JM, Torgerson D, Gignoux CR, Sen S, Roth LA, Via M, Aldrich MC, Eng C, Huntsman S, Rodriguez-Santana J, Rodriguez-Cintrón W, Chapela R, Ford JG, Burchard EG. PMID: 21621256; PMCID: PMC3129381.
View in:
PubMed Mentions:
20 Fields:
Translation:
Humans
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History shaped the geographic distribution of genomic admixture on the island of Puerto Rico. PLoS One. 2011 Jan 31; 6(1):e16513.
Via M, Gignoux CR, Roth LA, Fejerman L, Galanter J, Choudhry S, Toro-Labrador G, Viera-Vera J, Oleksyk TK, Beckman K, Ziv E, Risch N, Burchard EG, Martínez-Cruzado JC. PMID: 21304981; PMCID: PMC3031579.
View in:
PubMed Mentions:
64 Fields:
Translation:
Humans
-
Ethical and practical guidelines for reporting genetic research results to study participants: updated guidelines from a National Heart, Lung, and Blood Institute working group. Circ Cardiovasc Genet. 2010 Dec; 3(6):574-80.
National Heart, Lung, and Blood Institute working group, Fabsitz RR, McGuire A, Sharp RR, Puggal M, Beskow LM, Biesecker LG, Bookman E, Burke W, Burchard EG, Church G, Clayton EW, Eckfeldt JH, Fernandez CV, Fisher R, Fullerton SM, Gabriel S, Gachupin F, James C, Jarvik GP, Kittles R, Leib JR, O'Donnell C, O'Rourke PP, Rodriguez LL, Schully SD, Shuldiner AR, Sze RK, Thakuria JV, Wolf SM, Burke GL. PMID: 21156933; PMCID: PMC3090664.
View in:
PubMed Mentions:
222 Fields:
Translation:
Humans
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Factors predicting inhaled corticosteroid responsiveness in African American patients with asthma. J Allergy Clin Immunol. 2010 Dec; 126(6):1131-8.
Gould W, Peterson EL, Karungi G, Zoratti A, Gaggin J, Toma G, Yan S, Levin AM, Yang JJ, Wells K, Wang M, Burke RR, Beckman K, Popadic D, Land SJ, Kumar R, Seibold MA, Lanfear DE, Burchard EG, Williams LK. PMID: 20864153; PMCID: PMC2998569.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
ALOX5AP and LTA4H polymorphisms modify augmentation of bronchodilator responsiveness by leukotriene modifiers in Latinos. J Allergy Clin Immunol. 2010 Oct; 126(4):853-8.
Tcheurekdjian H, Via M, De Giacomo A, Corvol H, Eng C, Thyne S, Chapela R, Rodriguez-Cintron W, Rodriguez-Santana JR, Avila PC, Burchard EG, Genetics of Asthma in Latino Americans Study. PMID: 20810156; PMCID: PMC2950217.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Dual-specificity phosphatase 1 as a pharmacogenetic modifier of inhaled steroid response among asthmatic patients. J Allergy Clin Immunol. 2010 Sep; 126(3):618-25.e1-2.
Jin Y, Hu D, Peterson EL, Eng C, Levin AM, Wells K, Beckman K, Kumar R, Seibold MA, Karungi G, Zoratti A, Gaggin J, Campbell J, Galanter J, Chapela R, Rodríguez-Santana JR, Watson HG, Meade K, Lenoir M, Rodríguez-Cintrón W, Avila PC, Lanfear DE, Burchard EG, Williams LK. PMID: 20673984; PMCID: PMC2943151.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCTClinical Trials
-
Genetic ancestry in lung-function predictions. N Engl J Med. 2010 Jul 22; 363(4):321-30.
Kumar R, Seibold MA, Aldrich MC, Williams LK, Reiner AP, Colangelo L, Galanter J, Gignoux C, Hu D, Sen S, Choudhry S, Peterson EL, Rodriguez-Santana J, Rodriguez-Cintron W, Nalls MA, Leak TS, O'Meara E, Meibohm B, Kritchevsky SB, Li R, Harris TB, Nickerson DA, Fornage M, Enright P, Ziv E, Smith LJ, Liu K, Burchard EG. PMID: 20647190; PMCID: PMC2922981.
View in:
PubMed Mentions:
133 Fields:
Translation:
Humans
-
GSNO reductase and beta2-adrenergic receptor gene-gene interaction: bronchodilator responsiveness to albuterol. Pharmacogenet Genomics. 2010 Jun; 20(6):351-8.
Choudhry S, Que LG, Yang Z, Liu L, Eng C, Kim SO, Kumar G, Thyne S, Chapela R, Rodriguez-Santana JR, Rodriguez-Cintron W, Avila PC, Stamler JS, Burchard EG. PMID: 20335826; PMCID: PMC2883564.
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
-
A genome-wide association study on African-ancestry populations for asthma. J Allergy Clin Immunol. 2010; 125(2)::336-346.e4..
Mathias RA, Grant AV, Rafaels N, Hand T, Gao L, Vergara C, Tsai YJ, Yang M, Campbell M, Foster C, Gao P, Togias A, Hansel NN, Diette G, Adkinson NF, Liu MC, Faruque M, Dunston GM, Watson HR, Bracken MB, Hoh J, Maul P, Maul T, Jedlicka AE, Murray T, Hetmanski JB, Ashworth R, Ongaco CM, Hetrick KN, Doheny KF, Pugh EW, Rotimi CN, Ford J, Eng C, Burchard EG, Sleiman PM, Hakonarson H, Forno E, Raby BA, Weiss ST, Scott AF, Kabesch M, Liang L, Abecasis G, Moffatt MF, Cookson WO, Ruczinski I, Beaty TH, Barnes KC. View Publication.
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The 1000 Genomes Project: new opportunities for research and social challenges. Genome Med. 2010 Jan 21; 2(1):3.
Via M, Gignoux C, Burchard EG. PMID: 20193048; PMCID: PMC2829928.
View in:
PubMed Mentions:
66 Fields:
-
The role of LTA4H and ALOX5AP genes in the risk for asthma in Latinos. Clin Exp Allergy. 2010 Apr; 40(4):582-9.
Via M, De Giacomo A, Corvol H, Eng C, Seibold MA, Gillett C, Galanter J, Sen S, Tcheurekdjian H, Chapela R, Rodríguez-Santana JR, Rodríguez-Cintrón W, Thyne S, Avila PC, Choudhry S, González Burchard E, Genetics of Asthma in Latino Americans (GALA) Study. PMID: 20067482; PMCID: PMC2866051.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
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Ancestry-related assortative mating in Latino populations. Genome Biol. 2009; 10(11):R132.
Risch N, Choudhry S, Via M, Basu A, Sebro R, Eng C, Beckman K, Thyne S, Chapela R, Rodriguez-Santana JR, Rodriguez-Cintron W, Avila PC, Ziv E, Gonzalez Burchard E. . PMID: 19930545; PMCID: PMC3091325.
View in:
PubMed Mentions:
57 Fields:
Translation:
Humans
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Institutional Profile: The University of California Pharmacogenomics Center: at the interface of genomics, biological mechanisms and drug therapy. Pharmacogenomics. 2009 Oct; 10(10):1569-76.
Kroetz DL, Ahituv N, Burchard EG, Guo S, Sali A, Giacomini KM. PMID: 19842929; PMCID: PMC2923222.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
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Recent advances of genetic ancestry testing in biomedical research and direct to consumer testing. Clin Genet. 2009 Sep; 76(3):225-35.
Via M, Ziv E, Burchard EG. PMID: 19793051; PMCID: PMC2857388.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
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Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children. PLoS Genet. 2009 Aug; 5(8):e1000623.
Hancock DB, Romieu I, Shi M, Sienra-Monge JJ, Wu H, Chiu GY, Li H, del Rio-Navarro BE, Willis-Owen SA, Willis-Owens SA, Weiss ST, Raby BA, Gao H, Eng C, Chapela R, Burchard EG, Tang H, Sullivan PF, London SJ. PMID: 19714205; PMCID: PMC2722731.
View in:
PubMed Mentions:
83 Fields:
Translation:
HumansCells
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Genetic ancestry modifies pharmacogenetic gene-gene interaction for asthma. Pharmacogenet Genomics. 2009 Jul; 19(7):489-96.
Corvol H, De Giacomo A, Eng C, Seibold M, Ziv E, Chapela R, Rodriguez-Santana JR, Rodriguez-Cintron W, Thyne S, Watson HG, Meade K, LeNoir M, Avila PC, Choudhry S, Burchard EG, Genetics of Asthma in Latino Americans (GALA) Study, Study of African-Americans, Asthma, Genes and Environments (SAGE) Investigators. PMID: 19503017; PMCID: PMC2768127.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
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Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin. Pharmacogenet Genomics. 2009 Jul; 19(7):497-504.
Chen Y, Li S, Brown C, Cheatham S, Castro RA, Leabman MK, Urban TJ, Chen L, Yee SW, Choi JH, Huang Y, Brett CM, Burchard EG, Giacomini KM. PMID: 19483665; PMCID: PMC3104496.
View in:
PubMed Mentions:
86 Fields:
Translation:
HumansCellsCTClinical Trials
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Augmentation of bronchodilator responsiveness by leukotriene modifiers in Puerto Rican and Mexican children. Ann Allergy Asthma Immunol. 2009 Jun; 102(6):510-7.
Tcheurekdjian H, Thyne SM, Williams LK, Via M, Rodriguez-Santana JR, Rodriguez-Cintron W, Avila PC, Burchard EG. PMID: 19558011; PMCID: PMC6853056.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
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Differential enzymatic activity of common haplotypic versions of the human acidic Mammalian chitinase protein. J Biol Chem. 2009 Jul 17; 284(29):19650-8.
Seibold MA, Reese TA, Choudhry S, Salam MT, Beckman K, Eng C, Atakilit A, Meade K, Lenoir M, Watson HG, Thyne S, Kumar R, Weiss KB, Grammer LC, Avila P, Schleimer RP, Fahy JV, Rodriguez-Santana J, Rodriguez-Cintron W, Boot RG, Sheppard D, Gilliland FD, Locksley RM, Burchard EG. PMID: 19435888; PMCID: PMC2740590.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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Race and ancestry in biomedical research: exploring the challenges. Genome Med. 2009 Jan 21; 1(1):8.
Caulfield T, Fullerton SM, Ali-Khan SE, Arbour L, Burchard EG, Cooper RS, Hardy BJ, Harry S, Hyde-Lay R, Kahn J, Kittles R, Koenig BA, Lee SS, Malinowski M, Ravitsky V, Sankar P, Scherer SW, Séguin B, Shickle D, Suarez-Kurtz G, Daar AS. PMID: 19348695; PMCID: PMC2651580.
View in:
PubMed Mentions:
52 Fields:
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Birthplace and mortality among insured Latinos: the paradox revisited. Ethn Dis. 2009; 19(2):185-91.
Iribarren C, Darbinian JA, Fireman BH, Burchard EG. PMID: 19537231.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
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Population admixture associated with disease prevalence in the Boston Puerto Rican health study. Hum Genet. 2009 Mar; 125(2):199-209.
Lai CQ, Tucker KL, Choudhry S, Parnell LD, Mattei J, García-Bailo B, Beckman K, Burchard EG, Ordovás JM. PMID: 19107526; PMCID: PMC2727756.
View in:
PubMed Mentions:
74 Fields:
Translation:
Humans
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Common variants in interleukin-1-Beta gene are associated with intracranial hemorrhage and susceptibility to brain arteriovenous malformation. Cerebrovasc Dis. 2009; 27(2):176-82.
Kim H, Hysi PG, Pawlikowska L, Poon A, Burchard EG, Zaroff JG, Sidney S, Ko NU, Achrol AS, Lawton MT, McCulloch CE, Kwok PY, Young WL. PMID: 19092239; PMCID: PMC2649796.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansCells
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Genetic ancestry and risk of breast cancer among U.S. Latinas. Cancer Res. 2008 Dec 01; 68(23):9723-8.
Fejerman L, John EM, Huntsman S, Beckman K, Choudhry S, Perez-Stable E, Burchard EG, Ziv E. PMID: 19047150; PMCID: PMC2674787.
View in:
PubMed Mentions:
76 Fields:
Translation:
Humans
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Relationship between recent short-acting beta-agonist use and subsequent asthma exacerbations. Ann Allergy Asthma Immunol. 2008 Nov; 101(5):482-7.
Paris J, Peterson EL, Wells K, Pladevall M, Burchard EG, Choudhry S, Lanfear DE, Williams LK. PMID: 19055201; PMCID: PMC2646829.
View in:
PubMed Mentions:
23 Fields:
Translation:
Humans
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Chitotriosidase is the primary active chitinase in the human lung and is modulated by genotype and smoking habit. J Allergy Clin Immunol. 2008 Nov; 122(5):944-950.e3.
Seibold MA, Donnelly S, Solon M, Innes A, Woodruff PG, Boot RG, Burchard EG, Fahy JV. PMID: 18845328; PMCID: PMC2666777.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansCells
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Differences in allergic sensitization by self-reported race and genetic ancestry. J Allergy Clin Immunol. 2008 Oct; 122(4):820-827.e9.
Yang JJ, Burchard EG, Choudhry S, Johnson CC, Ownby DR, Favro D, Chen J, Akana M, Ha C, Kwok PY, Krajenta R, Havstad SL, Joseph CL, Seibold MA, Shriver MD, Williams LK. PMID: 19014772; PMCID: PMC2951327.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansPHPublic Health
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An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity. Hum Mol Genet. 2008 Sep 01; 17(17):2681-90.
Seibold MA, Wang B, Eng C, Kumar G, Beckman KB, Sen S, Choudhry S, Meade K, Lenoir M, Watson HG, Thyne S, Williams LK, Kumar R, Weiss KB, Grammer LC, Avila PC, Schleimer RP, Burchard EG, Brenner R. PMID: 18535015; PMCID: PMC2733805.
View in:
PubMed Mentions:
46 Fields:
Translation:
Humans
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Inhaled corticosteroids and augmented bronchodilator responsiveness in Latino and African American asthmatic patients. Ann Allergy Asthma Immunol. 2008 Jun; 100(6):551-7.
Naqvi M, Tcheurekdjian H, DeBoard JA, Williams LK, Navarro D, Castro RA, Rodriguez-Santana JR, Chapela R, Watson HG, Meade K, Rodriguez-Cintron W, LeNoir M, Thyne SM, Avila PC, Choudhry S, Burchard EG. PMID: 18592818.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Comparing genetic ancestry and self-described race in african americans born in the United States and in Africa. Cancer Epidemiol Biomarkers Prev. 2008 Jun; 17(6):1329-38.
Yaeger R, Avila-Bront A, Abdul K, Nolan PC, Grann VR, Birchette MG, Choudhry S, Burchard EG, Beckman KB, Gorroochurn P, Ziv E, Consedine NS, Joe AK. PMID: 18559547; PMCID: PMC2507870.
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PubMed Mentions:
85 Fields:
Translation:
Humans
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Pharmacogenetic response to albuterol among asthmatics. Pharmacogenomics. 2008; 9(5):505-10.
Corvol H, Burchard EG.
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Genome-wide screen for asthma in Puerto Ricans: evidence for association with 5q23 region. Hum Genet. 2008 Jun; 123(5):455-68.
Choudhry S, Taub M, Mei R, Rodriguez-Santana J, Rodriguez-Cintron W, Shriver MD, Ziv E, Risch NJ, Burchard EG. PMID: 18401594; PMCID: PMC2664533.
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48 Fields:
Translation:
HumansCells
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Race, ethnicity and social class and the complex etiologies of asthma. Pharmacogenomics. 2008 Apr; 9(4):453-62.
Drake KA, Galanter JM, Burchard EG. PMID: 18384258; PMCID: PMC2746736.
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PubMed Mentions:
31 Fields:
Translation:
HumansAnimals
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ORMDL3 gene is associated with asthma in three ethnically diverse populations. Am J Respir Crit Care Med. 2008 Jun 01; 177(11):1194-200.
Galanter J, Choudhry S, Eng C, Nazario S, Rodríguez-Santana JR, Casal J, Torres-Palacios A, Salas J, Chapela R, Watson HG, Meade K, LeNoir M, Rodríguez-Cintrón W, Avila PC, Burchard EG. PMID: 18310477; PMCID: PMC2408437.
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PubMed Mentions:
103 Fields:
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Humans
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Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics. Clin Pharmacol Ther. 2008; 83(2):273-80.
Shu Y, Brown C, Castro RA, Shi RJ, Lin ET, Owen RP, Sheardown SA, Yue L, Burchard EG, Brett CM, Giacomini KM. View Publication.
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Gene-environment interactions between CD14 C-260T and endotoxin exposure on Foxp3+ and Foxp3- CD4+ lymphocyte numbers and total serum IgE levels in early childhood. Ann Allergy Asthma Immunol. 2008 Feb; 100(2):128-36.
Williams LK, Oliver J, Peterson EL, Bobbitt KR, McCabe MJ, Smolarek D, Havstad SL, Wegienka G, Burchard EG, Ownby DR, Johnson CC. PMID: 18320914; PMCID: PMC2646830.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Latino populations: a unique opportunity for epidemiological research of asthma. Paediatr Perinat Epidemiol. 2007 Nov; 21 Suppl 3:15-22.
Salari K, Burchard EG. PMID: 17935571.
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14 Fields:
Translation:
Humans
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Ethnic-specific differences in bronchodilator responsiveness among African Americans, Puerto Ricans, and Mexicans with asthma. J Asthma. 2007 Oct; 44(8):639-48.
Naqvi M, Thyne S, Choudhry S, Tsai HJ, Navarro D, Castro RA, Nazario S, Rodriguez-Santana JR, Casal J, Torres A, Chapela R, Watson HG, Meade K, LeNoir M, Avila PC, Rodriguez-Cintron W, Burchard EG. PMID: 17943575.
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PubMed Mentions:
36 Fields:
Translation:
Humans
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Functional effects of protein sequence polymorphisms in the organic cation/ergothioneine transporter OCTN1 (SLC22A4). Pharmacogenet Genomics. 2007 Sep; 17(9):773-82.
Urban TJ, Yang C, Lagpacan LL, Brown C, Castro RA, Taylor TR, Huang CC, Stryke D, Johns SJ, Kawamoto M, Carlson EJ, Ferrin TE, Burchard EG, Giacomini KM. PMID: 17700366.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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PCA-correlated SNPs for structure identification in worldwide human populations. PLoS Genet. 2007 Sep; 3(9):1672-86.
Paschou P, Ziv E, Burchard EG, Choudhry S, Rodriguez-Cintron W, Mahoney MW, Drineas P. PMID: 17892327; PMCID: PMC1988848.
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PubMed Mentions:
93 Fields:
Translation:
Humans
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Recent genetic selection in the ancestral admixture of Puerto Ricans. Am J Hum Genet. 2007 Sep; 81(3):626-33.
Tang H, Choudhry S, Mei R, Morgan M, Rodriguez-Cintron W, Burchard EG, Risch NJ. PMID: 17701908; PMCID: PMC1950843.
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PubMed Mentions:
102 Fields:
Translation:
HumansCells
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Effects of genetic variation in the novel organic cation transporter, OCTN1, on the renal clearance of gabapentin. Clin Pharmacol Ther. 2008 Mar; 83(3):416-21.
Urban TJ, Brown C, Castro RA, Shah N, Mercer R, Huang Y, Brett CM, Burchard EG, Giacomini KM. PMID: 17609685.
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PubMed Mentions:
34 Fields:
Translation:
HumansCells
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Dissecting complex diseases in complex populations: asthma in latino americans. Proc Am Thorac Soc. 2007 Jul; 4(3):226-33.
Choudhry S, Seibold MA, Borrell LN, Tang H, Serebrisky D, Chapela R, Rodriguez-Santana JR, Avila PC, Ziv E, Rodriguez-Cintron W, Risch NJ, Burchard EG. PMID: 17607004; PMCID: PMC2647623.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Association between IgE levels and asthma severity among African American, Mexican, and Puerto Rican patients with asthma. J Allergy Clin Immunol. 2007 Jul; 120(1):137-43.
Naqvi M, Choudhry S, Tsai HJ, Thyne S, Navarro D, Nazario S, Rodriguez-Santana JR, Casal J, Torres A, Chapela R, Watson HG, Meade K, Rodriguez-Cintron W, Lenoir M, Avila PC, Burchard EG. PMID: 17498790.
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PubMed Mentions:
27 Fields:
Translation:
Humans
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Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action. J Clin Invest. 2007 May; 117(5):1422-31.
Shu Y, Sheardown SA, Brown C, Owen RP, Zhang S, Castro RA, Ianculescu AG, Yue L, Lo JC, Burchard EG, Brett CM, Giacomini KM. PMID: 17476361; PMCID: PMC1857259.
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PubMed Mentions:
329 Fields:
Translation:
HumansAnimalsCells
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Determinants of airflow obstruction in severe alpha-1-antitrypsin deficiency. Thorax. 2007 Sep; 62(9):806-13.
Demeo DL, Sandhaus RA, Barker AF, Brantly ML, Eden E, McElvaney NG, Rennard S, Burchard E, Stocks JM, Stoller JK, Strange C, Turino GM, Campbell EJ, Silverman EK. PMID: 17389752; PMCID: PMC2117297.
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PubMed Mentions:
49 Fields:
Translation:
Humans
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Ethnicity-specific gene-gene interaction between IL-13 and IL-4Ralpha among African Americans with asthma. Am J Respir Crit Care Med. 2007 May 01; 175(9):881-7.
Battle NC, Choudhry S, Tsai HJ, Eng C, Kumar G, Beckman KB, Naqvi M, Meade K, Watson HG, Lenoir M, Burchard EG, SAGE Investigators. PMID: 17303794; PMCID: PMC1899298.
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PubMed Mentions:
38 Fields:
Translation:
Humans
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African ancestry, socioeconomic status, and kidney function in elderly African Americans: a genetic admixture analysis. J Am Soc Nephrol. 2006 Dec; 17(12):3491-6.
Peralta CA, Ziv E, Katz R, Reiner A, Burchard EG, Fried L, Kwok PY, Psaty B, Shlipak M. PMID: 17082243.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Genetic ancestry and risk factors for breast cancer among Latinas in the San Francisco Bay Area. Cancer Epidemiol Biomarkers Prev. 2006 Oct; 15(10):1878-85.
Ziv E, John EM, Choudhry S, Kho J, Lorizio W, Perez-Stable EJ, Burchard EG. PMID: 17035394; PMCID: PMC5033763.
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PubMed Mentions:
35 Fields:
Translation:
HumansPHPublic Health
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The PTGDR gene is not associated with asthma in 3 ethnically diverse populations. J Allergy Clin Immunol. 2006 Dec; 118(6):1242-8.
Tsai YJ, Choudhry S, Kho J, Beckman K, Tsai HJ, Navarro D, Matallana H, Castro RA, Lilly CM, Nazario S, Rodriguez-Santana JR, Casal J, Torres A, Salas J, Chapela R, Watson HG, Meade K, Avila PC, Rodriguez-Cintron W, LeNoir M, Burchard EG, Genetics of Asthma in Latino Americans Study, Study of African Americans, Asthma, Genes and Environments Investigators. PMID: 17157653.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Ancestry-environment interactions and asthma risk among Puerto Ricans. Am J Respir Crit Care Med. 2006 Nov 15; 174(10):1088-93.
Choudhry S, Burchard EG, Borrell LN, Tang H, Gomez I, Naqvi M, Nazario S, Torres A, Casal J, Martinez-Cruzado JC, Ziv E, Avila PC, Rodriguez-Cintron W, Risch NJ. PMID: 16973984; PMCID: PMC2648109.
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PubMed Mentions:
40 Fields:
Translation:
Humans
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Functional genetic diversity in the high-affinity carnitine transporter OCTN2 (SLC22A5). Mol Pharmacol. 2006 Nov; 70(5):1602-11.
Urban TJ, Gallagher RC, Brown C, Castro RA, Lagpacan LL, Brett CM, Taylor TR, Carlson EJ, Ferrin TE, Burchard EG, Packman S, Giacomini KM. PMID: 16931768.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Array comparative genomic hybridization in patients with congenital diaphragmatic hernia: mapping of four CDH-critical regions and sequencing of candidate genes at 15q26.1-15q26.2. Eur J Hum Genet. 2006 Sep; 14(9):999-1008.
Slavotinek AM, Moshrefi A, Davis R, Leeth E, Schaeffer GB, Burchard GE, Shaw GM, James B, Ptacek L, Pennacchio LA. PMID: 16736036.
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PubMed Mentions:
36 Fields:
Translation:
HumansCells
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Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants. J Pharmacol Exp Ther. 2006 Aug; 318(2):521-9.
Badagnani I, Castro RA, Taylor TR, Brett CM, Huang CC, Stryke D, Kawamoto M, Johns SJ, Ferrin TE, Carlson EJ, Burchard EG, Giacomini KM. PMID: 16702441.
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PubMed Mentions:
61 Fields:
Translation:
HumansAnimalsCells
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Beta 2-adrenergic receptor polymorphisms: pharmacogenetic response to bronchodilator among African American asthmatics. Hum Genet. 2006 Jun; 119(5):547-57.
Tsai HJ, Shaikh N, Kho JY, Battle N, Naqvi M, Navarro D, Matallana H, Lilly CM, Eng CS, Kumar G, Thyne S, Watson HG, Meade K, LeNoir M, Choudhry S, Burchard EG, Study of African Americans, Asthma, Genes Environments (SAGE). PMID: 16596417.
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PubMed Mentions:
36 Fields:
Translation:
Humans
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PharmGKB submission update: V. PMT submissions of genetic variation in SLC22 family transporters. Pharmacol Rev. 2006 Mar; 58(1):3-4.
Shu Y, Urban TJ, Leabman MK, Fujita T, Erdman AR, Lagpacan LL, Brown C, Castro RA, Huang CC, Stryke D, Kawamoto M, Johns SJ, Taylor TR, Chan W, De La Cruz M, Carlson EJ, Ferrin TE, Brett CM, Burchard EG, Herskowitz I, Kroetz DL, Giacomini KM. PMID: 16507878.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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PharmGKB submission update: VI. PMT submissions of genetic variations in neurotransmitter transporters (SLC6, SLC17, and SLC18) to the PharmGKB network. Pharmacol Rev. 2006 Mar; 58(1):5-6.
Badagnani I, Sorani M, Edwards RH, Brown C, Castro RA, Huang CC, Stryke D, Kawamoto M, Johns SJ, Carlson EJ, Taylor T, Chan W, De La Cruz M, Ferrin TE, Burchard EG, Herskowitz I, Kroetz DL, Giacomini KM. PMID: 16507879.
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1 Fields:
Translation:
Humans
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The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics. Am J Physiol Renal Physiol. 2006 Apr; 290(4):F905-12.
Erdman AR, Mangravite LM, Urban TJ, Lagpacan LL, Castro RA, de la Cruz M, Chan W, Huang CC, Johns SJ, Kawamoto M, Stryke D, Taylor TR, Carlson EJ, Ferrin TE, Brett CM, Burchard EG, Giacomini KM. PMID: 16291576.
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PubMed Mentions:
37 Fields:
Translation:
Humans
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Population stratification confounds genetic association studies among Latinos. Hum Genet. 2006 Jan; 118(5):652-64.
Choudhry S, Coyle NE, Tang H, Salari K, Lind D, Clark SL, Tsai HJ, Naqvi M, Phong A, Ung N, Matallana H, Avila PC, Casal J, Torres A, Nazario S, Castro R, Battle NC, Perez-Stable EJ, Kwok PY, Sheppard D, Shriver MD, Rodriguez-Cintron W, Risch N, Ziv E, Burchard EG, Genetics of Asthma in Latino Americans GALA Study. PMID: 16283388.
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PubMed Mentions:
116 Fields:
Translation:
Humans
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Admixture-matched case-control study: a practical approach for genetic association studies in admixed populations. Hum Genet. 2006 Jan; 118(5):626-39.
Tsai HJ, Kho JY, Shaikh N, Choudhry S, Naqvi M, Navarro D, Matallana H, Castro R, Lilly CM, Watson HG, Meade K, Lenoir M, Thyne S, Ziv E, Burchard EG. PMID: 16273390; PMCID: PMC3478103.
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PubMed Mentions:
19 Fields:
Translation:
Humans
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Comparison of three methods to estimate genetic ancestry and control for stratification in genetic association studies among admixed populations. Hum Genet. 2005 Dec; 118(3-4):424-33.
Tsai HJ, Choudhry S, Naqvi M, Rodriguez-Cintron W, Burchard EG, Ziv E. PMID: 16208514.
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PubMed Mentions:
67 Fields:
Translation:
Humans
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Polymorphisms in transforming growth factor-beta-related genes ALK1 and ENG are associated with sporadic brain arteriovenous malformations. Stroke. 2005 Oct; 36(10):2278-80.
Pawlikowska L, Tran MN, Achrol AS, Ha C, Burchard E, Choudhry S, Zaroff J, Lawton MT, Castro R, McCulloch CE, Marchuk D, Kwok PY, Young WL, UCSF BAVM Study Project. PMID: 16179574.
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PubMed Mentions:
33 Fields:
Translation:
Humans
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Genetic admixture and asthma-related phenotypes in Mexican American and Puerto Rican asthmatics. Genet Epidemiol. 2005 Jul; 29(1):76-86.
Salari K, Choudhry S, Tang H, Naqvi M, Lind D, Avila PC, Coyle NE, Ung N, Nazario S, Casal J, Torres-Palacios A, Clark S, Phong A, Gomez I, Matallana H, Pérez-Stable EJ, Shriver MD, Kwok PY, Sheppard D, Rodriguez-Cintron W, Risch NJ, Burchard EG, Ziv E. PMID: 15918156.
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PubMed Mentions:
94 Fields:
Translation:
Humans
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CD14 tobacco gene-environment interaction modifies asthma severity and immunoglobulin E levels in Latinos with asthma. Am J Respir Crit Care Med. 2005 Jul 15; 172(2):173-82.
Choudhry S, Avila PC, Nazario S, Ung N, Kho J, Rodriguez-Santana JR, Casal J, Tsai HJ, Torres A, Ziv E, Toscano M, Sylvia JS, Alioto M, Salazar M, Gomez I, Fagan JK, Salas J, Lilly C, Matallana H, Castro RA, Selman M, Weiss ST, Ford JG, Drazen JM, Rodriguez-Cintron W, Chapela R, Silverman EK, Burchard EG. PMID: 15879416.
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PubMed Mentions:
37 Fields:
Translation:
HumansPHPublic Health
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Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1). Pharmacogenet Genomics. 2005 Apr; 15(4):201-9.
Fujita T, Brown C, Carlson EJ, Taylor T, de la Cruz M, Johns SJ, Stryke D, Kawamoto M, Fujita K, Castro R, Chen CW, Lin ET, Brett CM, Burchard EG, Ferrin TE, Huang CC, Leabman MK, Giacomini KM. PMID: 15864112.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
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Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study. Am J Hum Genet. 2005 Mar; 76(3):463-77.
Reiner AP, Ziv E, Lind DL, Nievergelt CM, Schork NJ, Cummings SR, Phong A, Burchard EG, Harris TB, Psaty BM, Kwok PY. PMID: 15660291; PMCID: PMC1196398.
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PubMed Mentions:
82 Fields:
Translation:
Humans
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Functional analysis of genetic variants in the human concentrative nucleoside transporter 3 (CNT3; SLC28A3). Pharmacogenomics J. 2005; 5(3):157-65.
Badagnani I, Chan W, Castro RA, Brett CM, Huang CC, Stryke D, Kawamoto M, Johns SJ, Ferrin TE, Carlson EJ, Burchard EG, Giacomini KM. PMID: 15738947.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthma. Am J Respir Crit Care Med. 2005 Mar 15; 171(6):563-70.
Choudhry S, Ung N, Avila PC, Ziv E, Nazario S, Casal J, Torres A, Gorman JD, Salari K, Rodriguez-Santana JR, Toscano M, Sylvia JS, Alioto M, Castro RA, Salazar M, Gomez I, Fagan JK, Salas J, Clark S, Lilly C, Matallana H, Selman M, Chapela R, Sheppard D, Weiss ST, Ford JG, Boushey HA, Drazen JM, Rodriguez-Cintron W, Silverman EK, Burchard EG. PMID: 15557128.
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PubMed Mentions:
81 Fields:
Translation:
Humans
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Lower bronchodilator responsiveness in Puerto Rican than in Mexican subjects with asthma. Am J Respir Crit Care Med. 2004 Feb 01; 169(3):386-92.
Burchard EG, Avila PC, Nazario S, Casal J, Torres A, Rodriguez-Santana JR, Toscano M, Sylvia JS, Alioto M, Salazar M, Gomez I, Fagan JK, Salas J, Lilly C, Matallana H, Ziv E, Castro R, Selman M, Chapela R, Sheppard D, Weiss ST, Ford JG, Boushey HA, Rodriguez-Cintron W, Drazen JM, Silverman EK, Genetics of Asthma in Latino Americans (GALA) Study. PMID: 14617512.
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PubMed Mentions:
89 Fields:
Translation:
Humans
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ADAM33 is not associated with asthma in Puerto Rican or Mexican populations. Am J Respir Crit Care Med. 2003 Dec 01; 168(11):1312-6.
Lind DL, Choudhry S, Ung N, Ziv E, Avila PC, Salari K, Ha C, Lovins EG, Coyle NE, Nazario S, Casal J, Torres A, Rodriguez-Santana JR, Matallana H, Lilly CM, Salas J, Selman M, Boushey HA, Weiss ST, Chapela R, Ford JG, Rodriguez-Cintron W, Silverman EK, Sheppard D, Kwok PY, González Burchard E. . PMID: 12958057.
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PubMed Mentions:
43 Fields:
Translation:
Humans
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Human population structure and genetic association studies. Pharmacogenomics. 2003 Jul; 4(4):431-41.
Ziv E, Burchard EG. PMID: 12831322.
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PubMed Mentions:
56 Fields:
Translation:
Humans
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The importance of race and ethnic background in biomedical research and clinical practice. N Engl J Med. 2003 Mar 20; 348(12):1170-5.
Burchard EG, Ziv E, Coyle N, Gomez SL, Tang H, Karter AJ, Mountain JL, Pérez-Stable EJ, Sheppard D, Risch N. PMID: 12646676.
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PubMed Mentions:
301 Fields:
Translation:
Humans
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Categorization of humans in biomedical research: genes, race and disease. Genome Biol. 2002 Jul 01; 3(7):comment2007.
Risch N, Burchard E, Ziv E, Tang H. PMID: 12184798; PMCID: PMC139378.
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PubMed Mentions:
170 Fields:
Translation:
Humans
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Association between a sequence variant in the IL-4 gene promoter and FEV(1) in asthma. Am J Respir Crit Care Med. 1999 Sep; 160(3):919-22.
Burchard EG, Silverman EK, Rosenwasser LJ, Borish L, Yandava C, Pillari A, Weiss ST, Hasday J, Lilly CM, Ford JG, Drazen JM. PMID: 10471619.
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PubMed Mentions:
42 Fields:
Translation:
HumansCells
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Cytokine gene expression in human cardiac allograft recipients. Transpl Immunol. 1994 Sep; 2(3):199-207.
Wu CJ, Kurbegov D, Lattin B, Burchard E, Finkle C, Valantine H, Billingham ME, Starnes VA, Clayberger C. PMID: 8000848.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Cytokine gene expression in human lung transplant recipients. Transplantation. 1993 Oct; 56(4):956-61.
Whitehead BF, Stoehr C, Wu CJ, Patterson G, Burchard EG, Theodore J, Clayberger C, Starnes VA. PMID: 7692639.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells