Ayesha Appa, MD

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
Address2540 23rd Street, #4110
San Francisco CA 94110
PronounsShe/Her/Hers
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    Collapse Biography 
    Collapse education and training
    Dartmouth College, Hanover, NHBA06/2007History modified with Biology
    University of California, San Francisco, San Francisco, CAMD with Distinction06/2014
    University of Washington, Seattle, WA06/2017Internal Medicine Residency
    University of Washington, Seattle, WA06/2018Chief Residency
    University of California, San Francisco, San Francisco, CA04/2023Infectious Diseases Fellowship
    University of California, San Francisco, San Francisco, CA08/2021Addiction Medicine Fellowship
    Johns Hopkins University04/2022 Inter-CFAR Implementation Science Fellowship
    Collapse awards and honors
    UCSF2013 Alpha Omega Alpha Honor Society
    UCSF2013 Gold Headed Cane Society Inductee
    University of Washington2017 Residency Excellence in Teaching Award
    University of Washington2018Housestaff Achievement Award
    UCSF2019Department of Medicine Clinical Fellow Award (Infectious Diseases)
    UCSF2022School of Medicine Bridges Curriculum Award: Excellence in Innovative Teaching Modalities
    UCSF2023 Population Health & Health Equity Scholarship
    UCSF2023Center for AIDS Research (CFAR) Early-Career Excellence Award in Clinical Research

    Collapse Overview 
    Collapse overview
    Dr. Ayesha Appa is an Assistant Professor of Medicine in the Division of HIV, Infectious Diseases, and Global Medicine at San Francisco General Hospital and a clinician investigator triply board-certified in Infectious Diseases, Addiction Medicine, and Internal Medicine. Her research program is centered on the integration of care for substance use disorders and HIV/serious infections, with an emphasis on implementing practical healthcare models.

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Viral Suppression Rates at 48 Weeks in People With HIV Starting Long-Acting Cabotegravir/Rilpivirine With Initial Viremia. Clin Infect Dis. 2025 Apr 30; 80(4):864-870. Hickey MD, Gistand N, Grochowski J, Mayorga-Munoz F, Imbert E, Szumowski JD, Oskarsson J, Shiels M, Dilworth S, Appa A, Havlir DV, Gandhi M, Christopoulos K. PMID: 39367871; PMCID: PMC12043055.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    2. Unintentional Fentanyl Use Detected in Hair of People With HIV Risk Using Methamphetamine. JAMA. 2025 Feb 26. Appa A, Spinelli MA, Javanbakht M, Heise MJ, Okochi H, Bazazi AR, Coffin P, Gorbach PM, Gandhi M. PMID: 40009421; PMCID: PMC11866066.
      View in: PubMed   Mentions:    Fields:    
    3. The Positioning of Ceftobiprole in the Treatment of Staphylococcus aureus Bacteremia. Clin Infect Dis. 2024 Dec 17; 79(6):1539-1540. Minter DJ, Appa A, Chambers HF, Doernberg SB. PMID: 38466317.
      View in: PubMed   Mentions:    Fields:    
    4. A Review of Implementation Strategies to Enhance PrEP Delivery for People Experiencing Housing Insecurity: Advancing a Multifaceted High-Touch, Low-Barrier Approach. Curr HIV/AIDS Rep. 2024 Nov 22; 22(1):4. Velloza J, Mehtani NJ, Hickey MD, Imbert E, Appa A, Riley ED. PMID: 39576385; PMCID: PMC11584499.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    5. High Retention and Adherence with Rapid Long-Acting Injectable PrEP Implementation in an Urban Safety-Net Clinic Population. Clin Infect Dis. 2024 Nov 01. Spinelli MA, Bisom-Rapp E, Heise MJ, Camp C, Appa A, Liu AY, Sassaman K, Shiels M, Mayorga-Munoz F, Chimezie A, Nguyen J, Oskarsson J, Gandhi M. PMID: 39484783.
      View in: PubMed   Mentions: 2     Fields:    
    6. Identifying Implementation Determinants and Strategies for Long-Acting Injectable Cabotegravir-Rilpivirine in People With HIV Who Are Virally Unsuppressed. J Acquir Immune Defic Syndr. 2024 07 01; 96(3):280-289. Hickey MD, Grochowski J, Mayorga-Munoz F, Oskarsson J, Imbert E, Spinelli M, Szumowski JD, Appa A, Koester K, Dauria EF, McNulty M, Colasanti J, Havlir DV, Gandhi M, Christopoulos KA. PMID: 38534179; PMCID: PMC11192618.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    7. Participant perspectives on incentives for TB preventative therapy adherence and reduced alcohol use: A qualitative study. PLOS Glob Public Health. 2024; 4(4):e0002472. Appa A, Miller AP, Fatch R, Kekibiina A, Beesiga B, Adong J, Emenyonu N, Marson K, Getahun M, Kamya M, Muyindike W, McDonell M, Thirumurthy H, Hahn JA, Chamie G, Camlin CS. PMID: 38656992; PMCID: PMC11042709.
      View in: PubMed   Mentions: 2  
    8. National HIV and HCV Screening Rates for Hospitalized People who Use Drugs Are Suboptimal and Heterogeneous Across 11 US Hospitals. Open Forum Infect Dis. 2024 May; 11(5):ofae204. Westgard LK, Sato T, Bradford WS, Eaton EF, Pilcher F, Hale AJ, Singh D, Martin M, Appa AA, Meyer JP, Weimer MB, Barakat LA, Felsen UR, Akiyama MJ, Ridgway JP, Grussing ED, Thakarar K, White A, Mutelayi J, Krsak M, Montague BT, Nijhawan A, Balakrishnan H, Marks LR, Wurcel AG. PMID: 38746950; PMCID: PMC11093397.
      View in: PubMed   Mentions: 2  
    9. Executive Summary: State-of-the-Art Review: Frame Shift-Focusing on Harm Reduction and Shared Decision Making for People Who Use Drugs Hospitalized With Infections. Clin Infect Dis. 2024 02 17; 78(2):233-235. Thakarar K, Appa A, Abdul Mutakabbir JC, Goff A, Brown J, Tuell C, Fairfield K, Wurcel A. PMID: 38018164; PMCID: PMC12098010.
      View in: PubMed   Mentions:    Fields:    
    10. Frame Shift: Focusing on Harm Reduction and Shared Decision Making for People Who Use Drugs Hospitalized With Infections. Clin Infect Dis. 2024 02 17; 78(2):e12-e26. Thakarar K, Appa A, Abdul Mutakabbir JC, Goff A, Brown J, Tuell C, Fairfield K, Wurcel A. PMID: 38018174; PMCID: PMC11487100.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. A Qualitative Exploration of Intimate Partner Violence Among HIV/TB Coinfected Persons With Problematic Alcohol Use Participating in an Incentive-Based Alcohol/Medication Adherence Intervention in Uganda During COVID-19. Violence Against Women. 2025 04; 31(5):1082-1103. Miller AP, Appa A, Muyindike W, Fatch R, Kekibiina A, Beesiga B, Adong J, Emenyonu N, Marson K, Getahun M, Kamya M, Chamie G, Camlin CS, Hahn JA. PMID: 38196278; PMCID: PMC11231058.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    12. Stimulant use and opioid-related harm in patients on long-term opioids for chronic pain. Drug Alcohol Depend. 2024 Mar 01; 256:111065. Appa A, McMahan VM, Long K, Shade SB, Coffin PO. PMID: 38245963; PMCID: PMC10999379.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    13. The IMPACT (Infection Management Plus Addiction Care Together) Pilot: A Case Series of Combined Contingency Management for Substance Use Disorders and Antibiotic Adherence in the Hospital Setting. J Addict Med. 2024 Mar-Apr 01; 18(2):138-143. Appa A, Baral S, Stein B, Knight K, Gandhi M, Coffin P, Martin M. PMID: 38109334; PMCID: PMC10939948.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Contemporary Management of Staphylococcus aureus Bacteremia-Controversies in Clinical Practice. Clin Infect Dis. 2023 11 30; 77(11):e57-e68. Minter DJ, Appa A, Chambers HF, Doernberg SB. PMID: 37950887; PMCID: PMC11959183.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    15. Executive Summary: State-of-The-Art Review: Contemporary Management of Staphylococcus aureus Bacteremia: Controversies in Clinical Practice. Clin Infect Dis. 2023 11 30; 77(11):1489-1491. Minter DJ, Appa A, Chambers HF, Doernberg SB. PMID: 38031168.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    16. HIV Treatment Outcomes in POP-UP: Drop-in HIV Primary Care Model for People Experiencing Homelessness. J Infect Dis. 2022 10 07; 226(Suppl 3):S353-S362. Hickey MD, Imbert E, Appa A, Del Rosario JB, Lynch E, Friend J, Avila R, Clemenzi-Allen A, Riley ED, Gandhi M, Havlir DV. PMID: 35759251; PMCID: PMC10233499.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    17. Engagement in HIV care and viral suppression following changes in long-term opioid therapy for treatment for chronic pain. AIDS Behav. 2022 Oct; 26(10):3220-3230. Silvis J, Rowe CL, Dobbins S, Haq N, Vittinghoff E, McMahan VM, Appa A, Coffin PO. PMID: 35380287; PMCID: PMC11230622.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Meeting people where they are: implementing hospital-based substance use harm reduction. Harm Reduct J. 2022 02 09; 19(1):14. Perera R, Stephan L, Appa A, Giuliano R, Hoffman R, Lum P, Martin M. PMID: 35139877; PMCID: PMC8826677.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    19. Comparative 1-Year Outcomes of Invasive Staphylococcus aureus Infections Among Persons With and Without Drug Use: An Observational Cohort Study. Clin Infect Dis. 2022 01 29; 74(2):263-270. Appa A, Adamo M, Le S, Davis J, Winston L, Doernberg SB, Chambers H, Martin M, Hills NK, Coffin PO, Jain V. PMID: 33904900; PMCID: PMC8800187.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    20. Can I Safely Discharge a Patient with a Substance Use Disorder Home with a Peripherally Inserted Central Catheter? NEJM Evid. 2022 02; 1(2):EVIDccon2100012. Appa A, Barocas JA. PMID: 38319183.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    21. Patient-Directed Discharges Among Persons Who Use Drugs Hospitalized with Invasive Staphylococcus aureus Infections: Opportunities for Improvement. Am J Med. 2022 01; 135(1):91-96. Appa A, Adamo M, Le S, Davis J, Winston L, Doernberg SB, Chambers H, Martin M, Hills NK, Coffin P, Jain V. PMID: 34508704; PMCID: PMC11552656.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    22. Community Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 Disproportionately Affects the Latinx Population During Shelter-in-Place in San Francisco. Clin Infect Dis. 2021 07 30; 73(Suppl 2):S127-S135. Chamie G, Marquez C, Crawford E, Peng J, Petersen M, Schwab D, Schwab J, Martinez J, Jones D, Black D, Gandhi M, Kerkhoff AD, Jain V, Sergi F, Jacobo J, Rojas S, Tulier-Laiwa V, Gallardo-Brown T, Appa A, Chiu C, Rodgers M, Hackett J, CLIAhub Consortium, Kistler A, Hao S, Kamm J, Dynerman D, Batson J, Greenhouse B, DeRisi J, Havlir DV. PMID: 32821935; PMCID: PMC7499499.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    23. SARS-CoV-2 PCR and antibody testing for an entire rural community: methods and feasibility of high-throughput testing procedures. Arch Public Health. 2021 Jul 07; 79(1):125. Appa A, Chamie G, Sawyer A, Baltzell K, Dippell K, Ribeiro S, Duarte E, Vinden J, Consortium C, Kramer-Feldman J, Rahdari S, MacIntosh D, Nicholson K, Im J, Havlir D, Greenhouse B. PMID: 34233752; PMCID: PMC8261397.
      View in: PubMed   Mentions: 5  
    24. Drug Overdose Deaths Before and After Shelter-in-Place Orders During the COVID-19 Pandemic in San Francisco. JAMA Netw Open. 2021 05 03; 4(5):e2110452. Appa A, Rodda LN, Cawley C, Zevin B, Coffin PO, Gandhi M, Imbert E. PMID: 33978726; PMCID: PMC8116981.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCellsPHPublic Health
    25. Beyond Overdose: Drug-Related Deaths in People With and Without HIV in San Francisco, 2007-2018. Open Forum Infect Dis. 2020 Dec; 7(12):ofaa565. Appa A, Rowe C, Hessol NA, Coffin P. PMID: 33409331; PMCID: PMC7757430.
      View in: PubMed   Mentions: 1  
    26. Universal Polymerase Chain Reaction and Antibody Testing Demonstrate Little to No Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 in a Rural Community. Open Forum Infect Dis. 2021 Jan; 8(1):ofaa531. Appa A, Takahashi S, Rodriguez-Barraquer I, Chamie G, Sawyer A, Duarte E, Hakim J, Turcios K, Vinden J, Janson O, Manglik A, Peluso MJ, Deeks SG, Henrich TJ, Torres L, Rodgers M, Hackett J, Chiu C, Havlir D, Greenhouse B. PMID: 34109255; PMCID: PMC7665736.
      View in: PubMed   Mentions: 7  
    27. Universal PCR and antibody testing demonstrate little to no transmission of SARS-CoV-2 in a rural community. medRxiv. 2020 Aug 17. Appa A, Takahashi S, Rodriguez-Barraquer I, Chamie G, Sawyer A, Consortium C, Duarte E, Hakim J, Turcios K, Vinden J, Janson O, Manglik A, Peluso MJ, Deeks SG, Henrich TJ, Torres L, Rodgers M, Hackett J, Chiu C, Havlir D, Greenhouse B. PMID: 32839781; PMCID: PMC7444294.
      View in: PubMed   Mentions:
    28. SARS-CoV-2 PCR and antibody testing for an entire rural community: methods and feasibility of high-throughput testing procedures. medRxiv. 2020 May 30. Appa A, Chamie G, Sawyer A, Baltzell K, Dippell K, Ribeiro S, Duarte E, Vinden J, CLIAHUB Consortium, Kramer-Feldman J, Rahdari S, MacIntosh D, Nicholson K, Im J, Havlir D, Greenhouse B. PMID: 32511482; PMCID: PMC7273250.
      View in: PubMed   Mentions:
    29. Home-Based Outpatient Parenteral Antibiotic Therapy at an Urban Safety Net Hospital: Comparing Outcomes in Persons With and Without Noninjection Drug Use. Open Forum Infect Dis. 2020 May; 7(5):ofaa162. Appa A, Marquez C, Jain V. PMID: 32494584; PMCID: PMC7252283.
      View in: PubMed   Mentions: 4  
    30. Characterizing Cefepime Neurotoxicity: A Systematic Review. Open Forum Infect Dis. 2017; 4(4):ofx170. Appa AA, Jain R, Rakita RM, Hakimian S, Pottinger PS. PMID: 29071284; PMCID: PMC5639733.
      View in: PubMed   Mentions: 47  
    31. The impact of multimorbidity on sexual function in middle-aged and older women: beyond the single disease perspective. J Sex Med. 2014 Nov; 11(11):2744-55. Appa AA, Creasman J, Brown JS, Van Den Eeden SK, Thom DH, Subak LL, Huang AJ. PMID: 25146458; PMCID: PMC4309673.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    32. Bicycle-related genitourinary injuries in the USA from 2002-2010. Inj Prev. 2014 Oct; 20(5):350-3. Tasian GE, Appa AA, Bagga HS, Blaschko S, McCulloch CE, McAninch JW, Breyer BN. PMID: 24618096; PMCID: PMC4161653.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    33. Selective angioembolization for traumatic renal injuries: a survey on clinician practice. World J Urol. 2014 Jun; 32(3):821-7. Glass AS, Appa AA, Kenfield SA, Bagga HS, Blaschko SD, McGeady JB, McAninch JW, Breyer BN. PMID: 24072011; PMCID: PMC4153381.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    34. Clinical predictors and significance of postvoid residual volume in women with diabetes. Diabetes Res Clin Pract. 2013 Aug; 101(2):164-9. Appa AA, Brown JS, Creasman J, Van Den Eeden SK, Subak LL, Thom DH, Ferrara A, Huang AJ. PMID: 23773505; PMCID: PMC3742560.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
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