Henry Chambers, III, MD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address1001 Potrero Ave
San Francisco CA 94110
Phone628-206-5437
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    Other Positions
    Title(s)Chief, Division of Infectious Diseases, SFGH

    Title(s)Director, Clinical Research Services, CTSI


    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency School of Medicine
    Vanderbilt UniversityM.D.School of Medicine
    Centre College Kentucky B.A.

    Collapse Overview 
    Collapse Overview
    Dr. Chambers clinical and research interests are antimicrobial drug resistance, staphylococcal infections, experimental therapeutics, and epidemiology and pathogenesis of disease caused by Staphylococcus aureus. He is editor for the Sanford Guide to Antimicrobial Therapy and he has over 200 original publications and textbook chapters in the areas of drug resistance, endocarditis, bacterial infections, and staphylococcal diseases.

    Dr. Chambers received his BA from Centre College in Kentucky and is a graduate of the Vanderbilt University School of Medicine. He trained in Internal Medicine and Infectious Diseases at the University of California San Francisco. Dr. Chambers has been a member of the medical faculty of the UCSF since 1983 where he currently is Professor of Medicine, Medical Director of Clinical Research Services for CTSI. He is an editor for Antimicrobial Agents and Chemotherapy, a reviewer for numerous medical publications, a peer reviewer for NIH study sections.

    Collapse Research 
    Collapse Research Activities and Funding
    Antibacterial Resistance Leadership Group (ARLG)
    NIH UM1AI104681Jun 1, 2013 - Nov 30, 2026
    Role: Co-Principal Investigator
    Novel Mechanisms of Beta-lactam Resistance in Staph Aureus
    NIH R01AI100291Aug 1, 2012 - Dec 31, 2022
    Role: Principal Investigator
    Novel Mechanisms of Beta-lactam Resistance in Staph Aureus
    NIH R56AI100291Aug 1, 2012 - Dec 31, 2017
    Role: Principal Investigator
    Genetic Basis of Virulence of Community MRSA Clone USA300
    NIH R01AI070289Apr 1, 2008 - Mar 31, 2012
    Role: Principal Investigator
    Gordon Research Conference on Staphylococcal Diseases
    NIH R13AI050556Jul 1, 2001 - Jun 30, 2002
    Role: Principal Investigator
    Biology of Infectious Diseases Training Program
    NIH T32AI007641Aug 1, 2000 - Aug 31, 2022
    Role: Principal Investigator
    PENICILLIN INTERACTIVE PROTEINS OF STAPHYLOCOCCUS AUREUS
    NIH R01AI046610Feb 1, 2000 - Jan 31, 2005
    Role: Principal Investigator
    GORDON CONFERENCE ON STAPHYLOCOCCAL DISEASES
    NIH R13AI043943May 1, 1999 - Apr 30, 2000
    Role: Principal Investigator
    VANCOMYCIN-RESISTANT STAPHYLOCOCCUS AUREUS
    NIH R03AI043959Apr 1, 1999 - Mar 31, 2002
    Role: Principal Investigator
    PENICILLIN BINDING PROTEINS OF STAPHYLOCOCCUS AUREUS
    NIH R21AI032496Sep 30, 1996 - Sep 29, 1999
    Role: Principal Investigator
    DEVELOPMENT OF DRUGS FOR TREATING TUBERCULOSIS
    NIH R01AI033702Sep 30, 1992 - Aug 31, 1997
    Role: Principal Investigator
    METHICILLIN RESISTANCE OF STAPHYLOCOCCUS AUREUS
    NIH R29AI027406Dec 1, 1988 - Nov 30, 1993
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000083Oct 1, 1974 - Nov 30, 2007
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Featured Content 
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A Combined Phenotypic-Genotypic Predictive Algorithm for In Vitro Detection of Bicarbonate: β-Lactam Sensitization among Methicillin-Resistant Staphylococcus aureus (MRSA). Antibiotics (Basel). 2021 Sep 09; 10(9). Ersoy SC, Rose WE, Patel R, Proctor RA, Chambers HF, Harrison EM, Pak Y, Bayer AS. PMID: 34572671; PMCID: PMC8469475.
      View in: PubMed   Mentions:
    2. Patient-Directed Discharges Among Persons Who Use Drugs Hospitalized with Invasive S. aureus Infections: Opportunities for Improvement. Am J Med. 2021 Sep 08. Appa A, Adamo M, Le S, Davis J, Winston L, Doernberg SB, Chambers H, Martin M, Hills NK, Coffin P, Jain V. PMID: 34508704.
      View in: PubMed   Mentions:    Fields:    
    3. Antibacterial Resistance Leadership Group 2.0: Back to Business. Clin Infect Dis. 2021 08 16; 73(4):730-739. Chambers HF, Evans SR, Patel R, Cross HR, Harris AD, Doi Y, Boucher HW, van Duin D, Tsalik EL, Holland TL, Pettigrew MM, Tamma PD, Hodges KR, Souli M, Fowler VG. PMID: 33588438.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    4. Trends in prevalence of extended-spectrum beta-lactamase-producing Escherichia coli isolated from patients with community- and healthcare-associated bacteriuria: results from 2014 to 2020 in an urban safety-net healthcare system. Antimicrob Resist Infect Control. 2021 08 11; 10(1):118. Raphael E, Glymour MM, Chambers HF. PMID: 34380549.
      View in: PubMed   Mentions:    Fields:    
    5. Comparative one-year outcomes of invasive Staphylococcus aureus infections among persons with and without drug use: an observational cohort study. Clin Infect Dis. 2021 Apr 27. Appa A, Adamo M, Le S, Davis J, Winston L, Doernberg SB, Chambers H, Martin M, Hills NK, Coffin PO, Jain V. PMID: 33904900.
      View in: PubMed   Mentions:    Fields:    
    6. Impact of Bicarbonate on PBP2a Production, Maturation, and Functionality in Methicillin-Resistant Staphylococcus aureus (MRSA). Antimicrob Agents Chemother. 2021 Mar 01. Ersoy SC, Chambers HF, Proctor RA, Rosato AE, Mishra NN, Xiong YQ, Bayer AS. PMID: 33649115.
      View in: PubMed   Mentions: 2     Fields:    
    7. Skin and Soft Tissue Infections. Infect Dis Clin North Am. 2021 03; 35(1):xiii-xiv. Chambers HF. PMID: 33494875.
      View in: PubMed   Mentions:    Fields:    
    8. Importance of non-pharmaceutical interventions in lowering the viral inoculum to reduce susceptibility to infection by SARS-CoV-2 and potentially disease severity. Lancet Infect Dis. 2021 09; 21(9):e296-e301. Spinelli MA, Glidden DV, Gennatas ED, Bielecki M, Beyrer C, Rutherford G, Chambers H, Goosby E, Gandhi M. PMID: 33631099.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    9. Skin and Soft Tissue Infections in Persons Who Inject Drugs. Infect Dis Clin North Am. 2021 Mar; 35(1):169-181. Chambers HF. PMID: 33303334.
      View in: PubMed   Mentions:    Fields:    
    10. Rifabutin to the Rescue? J Infect Dis. 2020 10 01; 222(9):1422-1424. Chambers HF. PMID: 32914842.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    11. Native-Valve Infective Endocarditis. N Engl J Med. 2020 08 06; 383(6):567-576. Chambers HF, Bayer AS. PMID: 32757525.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    12. Differential Trends in Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Infections in Four Health Care Facilities in a Single Metropolitan Area: A Retrospective Analysis. Microb Drug Resist. 2021 Feb; 27(2):154-161. Raphael E, Chambers HF. PMID: 32589493.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    13. Structural analysis of avibactam-mediated activation of the bla and mec divergons in methicillin-resistant Staphylococcus aureus. J Biol Chem. 2020 08 07; 295(32):10870-10884. Alexander JAN, Radaeva M, King DT, Chambers HF, Cherkasov A, Chatterjee SS, Strynadka NCJ. PMID: 32518158.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    14. Scope and Predictive Genetic/Phenotypic Signatures of Bicarbonate (NaHCO3) Responsiveness and β-Lactam Sensitization in Methicillin-Resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2020 04 21; 64(5). Ersoy SC, Otmishi M, Milan VT, Li L, Pak Y, Mediavilla J, Chen L, Kreiswirth B, Chambers HF, Proctor RA, Xiong YQ, Fowler VG, Bayer AS. PMID: 32041719.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    15. The Emperor's New Clothes: PRospective Observational Evaluation of the Association Between Initial VancomycIn Exposure and Failure Rates Among ADult HospitalizEd Patients With Methicillin-resistant Staphylococcus aureus Bloodstream Infections (PROVIDE). Clin Infect Dis. 2020 04 10; 70(8):1536-1545. Lodise TP, Rosenkranz SL, Finnemeyer M, Evans S, Sims M, Zervos MJ, Creech CB, Patel PC, Keefer M, Riska P, Silveira FP, Scheetz M, Wunderink RG, Rodriguez M, Schrank J, Bleasdale SC, Schultz S, Barron M, Stapleton A, Wray D, Chambers H, Fowler VG, Holland TL. PMID: 31157370.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    16. Analytical Evaluation of the Abbott RealTime CT/NG Assay for Detection of Chlamydia trachomatis and Neisseria gonorrhoeae in Rectal and Pharyngeal Swabs. J Mol Diagn. 2020 06; 22(6):811-816. Adamson PC, Pandori MW, Doernberg SB, Komarow L, Sund Z, Tran TTT, Jensen D, Tsalik EL, Deal CD, Chambers HF, Fowler VG, Evans SR, Patel R, Klausner JD, Antibacterial Resistance Leadership Group . PMID: 32247863.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    17. Molecular and clinical epidemiology of carbapenem-resistant Enterobacterales in the USA (CRACKLE-2): a prospective cohort study. Lancet Infect Dis. 2020 06; 20(6):731-741. van Duin D, Arias CA, Komarow L, Chen L, Hanson BM, Weston G, Cober E, Garner OB, Jacob JT, Satlin MJ, Fries BC, Garcia-Diaz J, Doi Y, Dhar S, Kaye KS, Earley M, Hujer AM, Hujer KM, Domitrovic TN, Shropshire WC, Dinh A, Manca C, Luterbach CL, Wang M, Paterson DL, Banerjee R, Patel R, Evans S, Hill C, Arias R, Chambers HF, Fowler VG, Kreiswirth BN, Bonomo RA, Multi-Drug Resistant Organism Network Investigators . PMID: 32151332.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    18. Ability of Bicarbonate Supplementation To Sensitize Selected Methicillin-Resistant Staphylococcus aureus Strains to β-Lactam Antibiotics in an Ex Vivo Simulated Endocardial Vegetation Model. Antimicrob Agents Chemother. 2020 02 21; 64(3). Rose WE, Bienvenida AM, Xiong YQ, Chambers HF, Bayer AS, Ersoy SC. PMID: 31844004.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    19. Is Daptomycin plus Ceftaroline Associated with Better Clinical Outcomes than Standard of Care Monotherapy for Staphylococcus aureus Bacteremia? Antimicrob Agents Chemother. 2019 11; 63(11). Kalil AC, Holubar M, Deresinski S, Chambers HF. PMID: 31640977.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    20. Bicarbonate Resensitization of Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics. Antimicrob Agents Chemother. 2019 07; 63(7). Ersoy SC, Abdelhady W, Li L, Chambers HF, Xiong YQ, Bayer AS. PMID: 31010857.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    21. Good Studies Evaluate the Disease While Great Studies Evaluate the Patient: Development and Application of a Desirability of Outcome Ranking Endpoint for Staphylococcus aureus Bloodstream Infection. Clin Infect Dis. 2019 05 02; 68(10):1691-1698. Doernberg SB, Tran TTT, Tong SYC, Paul M, Yahav D, Davis JS, Leibovici L, Boucher HW, Corey GR, Cosgrove SE, Chambers HF, Fowler VG, Evans SR, Holland TL, Antibacterial Resistance Leadership Group . PMID: 30321315.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    22. A Prognostic Model of Persistent Bacteremia and Mortality in Complicated Staphylococcus aureus Bloodstream Infection. Clin Infect Dis. 2019 04 24; 68(9):1502-1511. Guimaraes AO, Cao Y, Hong K, Mayba O, Peck MC, Gutierrez J, Ruffin F, Carrasco-Triguero M, Dinoso JB, Clemenzi-Allen A, Koss CA, Maskarinec SA, Chambers HF, Fowler VG, Baruch A, Rosenberger CM. PMID: 30165412.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    23. Omadacycline - The Newest Tetracycline. N Engl J Med. 2019 02 07; 380(6):588-589. Chambers HF. PMID: 30726683.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    24. Structural and kinetic analyses of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus. J Biol Chem. 2018 12 21; 293(51):19854-19865. Alexander JAN, Chatterjee SS, Hamilton SM, Eltis LD, Chambers HF, Strynadka NCJ. PMID: 30366985.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    25. Essential Resources and Strategies for Antibiotic Stewardship Programs in the Acute Care Setting. Clin Infect Dis. 2018 09 28; 67(8):1168-1174. Doernberg SB, Abbo LM, Burdette SD, Fishman NO, Goodman EL, Kravitz GR, Leggett JE, Moehring RW, Newland JG, Robinson PA, Spivak ES, Tamma PD, Chambers HF. PMID: 29590355.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    26. PBP4: A New Perspective on Staphylococcus aureus β-Lactam Resistance. Microorganisms. 2018 06 22; 6(3). da Costa TM, de Oliveira CR, Chambers HF, Chatterjee SS. PMID: 29932109.
      View in: PubMed   Mentions:
    27. PBP4 activity and its overexpression are necessary for PBP4-mediated high-level β-lactam resistance. J Antimicrob Chemother. 2018 05 01; 73(5):1177-1180. Basuino L, Jousselin A, Alexander JAN, Strynadka NCJ, Pinho MG, Chambers HF, Chatterjee SS. PMID: 29360990.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    28. Sulfamethoxazole-Trimethoprim (Cotrimoxazole) for Skin and Soft Tissue Infections Including Impetigo, Cellulitis, and Abscess. Open Forum Infect Dis. 2017; 4(4):ofx232. Bowen AC, Carapetis JR, Currie BJ, Fowler V, Chambers HF, Tong SYC. PMID: 29255730.
      View in: PubMed   Mentions:
    29. PBP4 Mediates β-Lactam Resistance by Altered Function. Antimicrob Agents Chemother. 2017 11; 61(11). Chatterjee SS, Chen L, Gilbert A, da Costa TM, Nair V, Datta SK, Kreiswirth BN, Chambers HF. PMID: 28807923.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    30. Prevalence of Slow-Growth Vancomycin Nonsusceptibility in Methicillin-Resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2017 11; 61(11). Katayama Y, Azechi T, Miyazaki M, Takata T, Sekine M, Matsui H, Hanaki H, Yahara K, Sasano H, Asakura K, Takaku T, Ochiai T, Komatsu N, Chambers HF. PMID: 28827421.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    31. Antimicrobial Stewardship Approaches in the Intensive Care Unit. Infect Dis Clin North Am. 2017 09; 31(3):513-534. Doernberg SB, Chambers HF. PMID: 28687210.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    32. A Placebo-Controlled Trial of Antibiotics for Smaller Skin Abscesses. N Engl J Med. 2017 06 29; 376(26):2545-2555. Daum RS, Miller LG, Immergluck L, Fritz S, Creech CB, Young D, Kumar N, Downing M, Pettibone S, Hoagland R, Eells SJ, Boyle MG, Parker TC, Chambers HF, DMID 07-0051 Team . PMID: 28657870.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    33. High-Level Resistance of Staphylococcus aureus to β-Lactam Antibiotics Mediated by Penicillin-Binding Protein 4 (PBP4). Antimicrob Agents Chemother. 2017 06; 61(6). Hamilton SM, Alexander JAN, Choo EJ, Basuino L, da Costa TM, Severin A, Chung M, Aedo S, Strynadka NCJ, Tomasz A, Chatterjee SS, Chambers HF. PMID: 28373193.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    34. Can Ceftazidime-Avibactam and Aztreonam Overcome β-Lactam Resistance Conferred by Metallo-β-Lactamases in Enterobacteriaceae? Antimicrob Agents Chemother. 2017 04; 61(4). Marshall S, Hujer AM, Rojas LJ, Papp-Wallace KM, Humphries RM, Spellberg B, Hujer KM, Marshall EK, Rudin SD, Perez F, Wilson BM, Wasserman RB, Chikowski L, Paterson DL, Vila AJ, van Duin D, Kreiswirth BN, Chambers HF, Fowler VG, Jacobs MR, Pulse ME, Weiss WJ, Bonomo RA. PMID: 28167541.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    35. The Antibacterial Resistance Leadership Group: Progress Report and Work in Progress. Clin Infect Dis. 2017 Mar 15; 64(suppl_1):S3-S7. Chambers HF, Cross HR, Evans SR, Kreiswirth BN, Fowler VG, Antibacterial Resistance Leadership Group (ARLG) . PMID: 28350896.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    36. Ceftaroline-Resistant, Daptomycin-Tolerant, and Heterogeneous Vancomycin-Intermediate Methicillin-Resistant Staphylococcus aureus Causing Infective Endocarditis. Antimicrob Agents Chemother. 2017 03; 61(3). Nigo M, Diaz L, Carvajal LP, Tran TT, Rios R, Panesso D, Garavito JD, Miller WR, Wanger A, Weinstock G, Munita JM, Arias CA, Chambers HF. PMID: 28232309.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    37. Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia. Infect Chemother. 2016 12; 48(4):267-273. Choo EJ, Chambers HF. PMID: 28032484.
      View in: PubMed   Mentions:
    38. IVIG-mediated protection against necrotizing pneumonia caused by MRSA. Sci Transl Med. 2016 09 21; 8(357):357ra124. Diep BA, Le VT, Badiou C, Le HN, Pinheiro MG, Duong AH, Wang X, Dip EC, Aguiar-Alves F, Basuino L, Marbach H, Mai TT, Sarda MN, Kajikawa O, Matute-Bello G, Tkaczyk C, Rasigade JP, Sellman BR, Chambers HF, Lina G. PMID: 27655850.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    39. Vancomycin MIC Does Not Predict 90-Day Mortality, Readmission, or Recurrence in a Prospective Cohort of Adults with Staphylococcus aureus Bacteremia. Antimicrob Agents Chemother. 2016 09; 60(9):5276-84. Baxi SM, Clemenzi-Allen A, Gahbauer A, Deck D, Imp B, Vittinghoff E, Chambers HF, Doernberg S. PMID: 27324762.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    40. Cefazolin versus Nafcillin for Methicillin-Sensitive Staphylococcus aureus Bloodstream Infection in a California Tertiary Medical Center. Antimicrob Agents Chemother. 2016 08; 60(8):4684-9. Pollett S, Baxi SM, Rutherford GW, Doernberg SB, Bacchetti P, Chambers HF. PMID: 27216053.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    41. Daptomycin-β-Lactam Combinations in a Rabbit Model of Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus Endocarditis. Antimicrob Agents Chemother. 2016 07; 60(7):3976-9. Chambers HF, Basuino L, Hamilton SM, Choo EJ, Moise P. PMID: 27090173.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    42. PBP 4 Mediates High-Level Resistance to New-Generation Cephalosporins in Staphylococcus aureus. Antimicrob Agents Chemother. 2016 07; 60(7):3934-41. Chan LC, Gilbert A, Basuino L, da Costa TM, Hamilton SM, Dos Santos KR, Chambers HF, Chatterjee SS. PMID: 27067335.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    43. Whole-Genome Sequencing of Methicillin-Resistant Staphylococcus aureus Resistant to Fifth-Generation Cephalosporins Reveals Potential Non-mecA Mechanisms of Resistance. PLoS One. 2016; 11(2):e0149541. Greninger AL, Chatterjee SS, Chan LC, Hamilton SM, Chambers HF, Chiu CY. PMID: 26890675.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    44. Comparative efficacies of tedizolid phosphate, vancomycin, and daptomycin in a rabbit model of methicillin-resistant Staphylococcus aureus endocarditis. Antimicrob Agents Chemother. 2015; 59(6):3252-6. Chan LC, Basuino L, Dip EC, Chambers HF. PMID: 25801564.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    45. Clindamycin versus trimethoprim-sulfamethoxazole for uncomplicated skin infections. N Engl J Med. 2015 Mar 19; 372(12):1093-103. Miller LG, Daum RS, Creech CB, Young D, Downing MD, Eells SJ, Pettibone S, Hoagland RJ, Chambers HF, DMID 07-0051 Team . PMID: 25785967.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    46. Ceftobiprole- and ceftaroline-resistant methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2015 May; 59(5):2960-3. Chan LC, Basuino L, Diep B, Hamilton S, Chatterjee SS, Chambers HF. PMID: 25753637.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    47. Probability of eradication using vancomycin alone or in combination for methicillin-resistant Staphylococcus aureus bacteremia. Antimicrob Agents Chemother. 2014 Dec; 58(12):7617. Chambers HF. PMID: 25392536.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    48. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014 Jul 15; 59(2):e10-52. Stevens DL, Bisno AL, Chambers HF, Dellinger EP, Goldstein EJ, Gorbach SL, Hirschmann JV, Kaplan SL, Montoya JG, Wade JC, Infectious Diseases Society of America . PMID: 24973422.
      View in: PubMed   Mentions: 316     Fields:    Translation:Humans
    49. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the infectious diseases society of America. Clin Infect Dis. 2014 Jul 15; 59(2):147-59. Stevens DL, Bisno AL, Chambers HF, Dellinger EP, Goldstein EJ, Gorbach SL, Hirschmann JV, Kaplan SL, Montoya JG, Wade JC. PMID: 24947530.
      View in: PubMed   Mentions: 154     Fields:    Translation:Humans
    50. Pharmacology and the treatment of complicated skin and skin-structure infections. N Engl J Med. 2014 Jun 05; 370(23):2238-9. Chambers HF. PMID: 24897088.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    51. Global gene expression of methicillin-resistant Staphylococcus aureus USA300 during human and mouse infection. J Infect Dis. 2014 May 15; 209(10):1542-50. Date SV, Modrusan Z, Lawrence M, Morisaki JH, Toy K, Shah IM, Kim J, Park S, Xu M, Basuino L, Chan L, Zeitschel D, Chambers HF, Tan MW, Brown EJ, Diep BA, Hazenbos WL. PMID: 24286981.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    52. Effects of linezolid on suppressing in vivo production of staphylococcal toxins and improving survival outcomes in a rabbit model of methicillin-resistant Staphylococcus aureus necrotizing pneumonia. J Infect Dis. 2013 Jul; 208(1):75-82. Diep BA, Afasizheva A, Le HN, Kajikawa O, Matute-Bello G, Tkaczyk C, Sellman B, Badiou C, Lina G, Chambers HF. PMID: 23532096.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    53. Epidemiologic Similarities in Pediatric Community-Associated Methicillin-Resistant and Methicillin-Sensitive Staphylococcus aureus in the San Francisco Bay Area. J Pediatric Infect Dis Soc. 2012 Sep; 1(3):200-11. Hsiang MS, Shiau R, Nadle J, Chan L, Lee B, Chambers HF, Pan E. PMID: 23687577.
      View in: PubMed   Mentions: 8     Fields:    
    54. Concurrent epidemics of skin and soft tissue infection and bloodstream infection due to community-associated methicillin-resistant Staphylococcus aureus. Clin Infect Dis. 2012 Sep; 55(6):781-8. Tattevin P, Schwartz BS, Graber CJ, Volinski J, Bhukhen A, Bhukhen A, Mai TT, Vo NH, Dang DN, Phan TH, Basuino L, Perdreau-Remington F, Chambers HF, Diep BA. PMID: 22670044.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCellsPHPublic Health
    55. Does doxycycline protect against development of Clostridium difficile infection? Clin Infect Dis. 2012 Sep; 55(5):615-20. Doernberg SB, Winston LG, Deck DH, Chambers HF. PMID: 22563022.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    56. Genetic pathway in acquisition and loss of vancomycin resistance in a methicillin resistant Staphylococcus aureus (MRSA) strain of clonal type USA300. PLoS Pathog. 2012 Feb; 8(2):e1002505. Gardete S, Kim C, Hartmann BM, Mwangi M, Roux CM, Dunman PM, Chambers HF, Tomasz A. PMID: 22319446.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    57. Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children: executive summary. Clin Infect Dis. 2011 Feb 01; 52(3):285-92. Liu C, Bayer A, Cosgrove SE, Daum RS, Fridkin SK, Gorwitz RJ, Kaplan SL, Karchmer AW, Levine DP, Murray BE, J Rybak M, Talan DA, Chambers HF. PMID: 21217178.
      View in: PubMed   Mentions: 426     Fields:    Translation:HumansCells
    58. Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children. Clin Infect Dis. 2011 Feb 01; 52(3):e18-55. Liu C, Bayer A, Cosgrove SE, Daum RS, Fridkin SK, Gorwitz RJ, Kaplan SL, Karchmer AW, Levine DP, Murray BE, J Rybak M, Talan DA, Chambers HF, Infectious Diseases Society of America . PMID: 21208910.
      View in: PubMed   Mentions: 647     Fields:    Translation:HumansCells
    59. A mecA-negative strain of methicillin-resistant Staphylococcus aureus with high-level β-lactam resistance contains mutations in three genes. Antimicrob Agents Chemother. 2010 Nov; 54(11):4900-2. Banerjee R, Gretes M, Harlem C, Basuino L, Chambers HF. PMID: 20805396.
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    72. Recurrence of skin and soft tissue infection caused by methicillin-resistant Staphylococcus aureus in a HIV primary care clinic. . 2008 Oct 01; 49(2):231-3. Graber CJ, Jacobson MA, Perdreau-Remington F, Chambers HF, Diep BA. PMID: 18820536.
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    84. Mechanism of cell surface expression of the Streptococcus mitis platelet binding proteins PblA and PblB. Mol Microbiol. 2007 May; 64(3):844-57. Mitchell J, Siboo IR, Takamatsu D, Chambers HF, Sullam PM. PMID: 17462028.
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    91. Efficacy of Telavancin in a rabbit model of aortic valve endocarditis due to methicillin-resistant Staphylococcus aureus or vancomycin-intermediate Staphylococcus aureus. Antimicrob Agents Chemother. 2005 Aug; 49(8):3163-5. Madrigal AG, Basuino L, Chambers HF. PMID: 16048918.
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    92. Imipenem for treatment of tuberculosis in mice and humans. Antimicrob Agents Chemother. 2005 Jul; 49(7):2816-21. Chambers HF, Turner J, Schecter GF, Kawamura M, Hopewell PC. PMID: 15980354.
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    93. Low colonization prevalence of Staphylococcus aureus with reduced vancomycin susceptibility among patients undergoing hemodialysis in the San Francisco Bay area. Clin Infect Dis. 2005 Jun 01; 40(11):1617-24. Hanna RF, Ward TJ, Chow DS, Lagana SM, Moreira RK, Emond JC, Weintraub JL, Prince MR, Eguia JM, Liu C, Moore M, Wrone EM, Pont J, Gerberding JL, Chambers HF. PMID: 15889359.
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    94. Role of SraP, a Serine-Rich Surface Protein of Staphylococcus aureus, in binding to human platelets. Infect Immun. 2005 Apr; 73(4):2273-80. Siboo IR, Chambers HF, Sullam PM. PMID: 15784571.
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    95. Evaluation of ceftobiprole in a rabbit model of aortic valve endocarditis due to methicillin-resistant and vancomycin-intermediate Staphylococcus aureus. Antimicrob Agents Chemother. 2005 Mar; 49(3):884-8. Chambers HF. PMID: 15728879.
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    96. An epidemic of methicillin-resistant Staphylococcus aureus soft tissue infections among medically underserved patients. Arch Surg. 2004 Sep; 139(9):947-51; discussion 951-3. Young DM, Harris HW, Charlebois ED, Chambers H, Campbell A, Perdreau-Remington F, Lee C, Mankani M, Mackersie R, Schecter WP. PMID: 15381611.
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    97. Crystal structures of the Apo and penicillin-acylated forms of the BlaR1 beta-lactam sensor of Staphylococcus aureus. J Biol Chem. 2004 Nov 05; 279(45):47278-87. Wilke MS, Hills TL, Zhang HZ, Chambers HF, Strynadka NC. PMID: 15322076.
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    98. Origins of community strains of methicillin-resistant Staphylococcus aureus. Clin Infect Dis. 2004 Jul 01; 39(1):47-54. Charlebois ED, Perdreau-Remington F, Kreiswirth B, Bangsberg DR, Ciccarone D, Diep BA, Ng VL, Chansky K, Edlin BR, Edlin B, Chambers HF. PMID: 15206052.
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    99. API 20 strep identification system may incorrectly speciate enterococci with low level resistance to vancomycin. Diagn Microbiol Infect Dis. 2004 Apr; 48(4):287-8. Winston LG, Pang S, Haller BL, Wong M, Chambers HF, Perdreau-Remington F. PMID: 15062923.
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    100. PBP 2a mutations producing very-high-level resistance to beta-lactams. Antimicrob Agents Chemother. 2004 Feb; 48(2):453-9. Katayama Y, Zhang HZ, Chambers HF. PMID: 14742194.
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    138. Treatment of infection and colonization caused by methicillin-resistant Staphylococcus aureus. Infect Control Hosp Epidemiol. 1991 Jan; 12(1):29-35. Chambers HF. PMID: 1847961.
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    139. Characterization of mechanisms of resistance to beta-lactam antibiotics in methicillin-resistant strains of Staphylococcus saprophyticus. Antimicrob Agents Chemother. 1990 Sep; 34(9):1780-2. Stratton CW, Gelfand MS, Gerberding JL, Chambers HF. PMID: 2285290.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    140. Binding affinity for penicillin-binding protein 2a correlates with in vivo activity of beta-lactam antibiotics against methicillin-resistant Staphylococcus aureus. J Infect Dis. 1990 Sep; 162(3):705-10. Chambers HF, Sachdeva M, Kennedy S. PMID: 2387996.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    141. Vancomycin for Staphylococcus aureus endocarditis in intravenous drug users. Antimicrob Agents Chemother. 1990 Jun; 34(6):1227-31. Small PM, Chambers HF. PMID: 2393284.
      View in: PubMed   Mentions: 109     Fields:    Translation:Humans
    142. Binding of beta-lactam antibiotics to penicillin-binding proteins in methicillin-resistant Staphylococcus aureus. J Infect Dis. 1990 Jun; 161(6):1170-6. Chambers HF, Sachdeva M. PMID: 2345297.
      View in: PubMed   Mentions: 48     Fields:    Translation:Cells
    143. Effects of dosage, peak and trough concentrations in serum, protein binding, and bactericidal rate on efficacy of teicoplanin in a rabbit model of endocarditis. Antimicrob Agents Chemother. 1990 Apr; 34(4):510-4. Chambers HF, Kennedy S. PMID: 2140496.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    144. Treatment of right-sided Staphylococcus aureus endocarditis in intravenous drug users with ciprofloxacin and rifampicin. Lancet. 1989 Nov 04; 2(8671):1071-3. Dworkin RJ, Lee BL, Sande MA, Chambers HF. PMID: 2572799.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    145. Evaluation of cilofungin (LY121019) for treatment of experimental Candida albicans endocarditis in rabbits. Antimicrob Agents Chemother. 1989 Oct; 33(10):1822-3. Padula A, Chambers HF. PMID: 2686548.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    146. Daptomycin (LY146032) for prevention and treatment of experimental aortic valve endocarditis in rabbits. Antimicrob Agents Chemother. 1989 Sep; 33(9):1522-5. Kennedy S, Chambers HF. PMID: 2554799.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    147. Methicillin-resistant staphylococci: genetics and mechanisms of resistance. Antimicrob Agents Chemother. 1989 Jul; 33(7):991-4. Hackbarth CJ, Chambers HF. PMID: 2675759.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    148. Methicillin-resistant staphylococci: detection methods and treatment of infections. Antimicrob Agents Chemother. 1989 Jul; 33(7):995-9. Hackbarth CJ, Chambers HF. PMID: 2675760.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    149. Low-level methicillin resistance in strains of Staphylococcus aureus. Antimicrob Agents Chemother. 1989 Apr; 33(4):424-8. Chambers HF, Archer G, Matsuhashi M. PMID: 2729937.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    150. Right-sided Staphylococcus aureus endocarditis in intravenous drug abusers: two-week combination therapy. Ann Intern Med. 1988 Oct 15; 109(8):619-24. Chambers HF, Miller RT, Newman MD. PMID: 3421575.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    151. Methicillin-resistant staphylococci. Clin Microbiol Rev. 1988 Apr; 1(2):173-86. Chambers HF. PMID: 3069195.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    152. Coagulase-negative staphylococci resistant to beta-lactam antibiotics in vivo produce penicillin-binding protein 2a. Antimicrob Agents Chemother. 1987 Dec; 31(12):1919-24. Chambers HF. PMID: 3439802.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    153. Effect of NaCl and nafcillin on penicillin-binding protein 2a and heterogeneous expression of methicillin resistance in Staphylococcus aureus. Antimicrob Agents Chemother. 1987 Dec; 31(12):1982-8. Chambers HF, Hackbarth CJ. PMID: 3439805.
      View in: PubMed   Mentions: 49     Fields:    Translation:Cells
    154. Comparative activity of CGP 31608, nafcillin, cefamandole, imipenem, and vancomycin against methicillin-susceptible and methicillin-resistant staphylococci. Antimicrob Agents Chemother. 1987 Oct; 31(10):1549-52. Sachdeva M, Hackbarth C, Stella FB, Chambers HF. PMID: 3481245.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    155. Emergence of resistance to cephalothin and gentamicin during combination therapy for methicillin-resistant Staphylococcus aureus endocarditis in rabbits. J Infect Dis. 1987 Mar; 155(3):581-5. Chambers HF, Miller MH. PMID: 3643249.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    156. Efficacy of ciprofloxacin for experimental endocarditis caused by methicillin-susceptible or -resistant strains of Staphylococcus aureus. Antimicrob Agents Chemother. 1986 Sep; 30(3):382-4. Carpenter TC, Hackbarth CJ, Chambers HF, Sande MA. PMID: 3640590.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    157. Serum bactericidal activity of rifampin in combination with other antimicrobial agents against Staphylococcus aureus. Antimicrob Agents Chemother. 1986 Apr; 29(4):611-3. Hackbarth CJ, Chambers HF, Sande MA. PMID: 3707110.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    158. Increased amounts of a novel penicillin-binding protein in a strain of methicillin-resistant Staphylococcus aureus exposed to nafcillin. J Clin Invest. 1985 Jul; 76(1):325-31. Chambers HF, Hartman BJ, Tomasz A. PMID: 4019783.
      View in: PubMed   Mentions: 57     Fields:    Translation:Cells
    159. Pefloxacin therapy for experimental endocarditis caused by methicillin-susceptible or methicillin-resistant strains of Staphylococcus aureus. Antimicrob Agents Chemother. 1985 May; 27(5):685-7. Sullam PM, Täuber MG, Hackbarth CJ, Chambers HF, Scott KG, Sande MA. PMID: 3860185.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    160. Failure of a once-daily regimen of cefonicid for treatment of endocarditis due to Staphylococcus aureus. Rev Infect Dis. 1984 Nov-Dec; 6 Suppl 4:S870-4. Chambers HF, Mills J, Drake TA, Sande MA. PMID: 6522927.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    161. Teicoplanin versus nafcillin and vancomycin in the treatment of experimental endocarditis caused by methicillin-susceptible or -resistant Staphylococcus aureus. Antimicrob Agents Chemother. 1984 Jul; 26(1):61-4. Chambers HF, Sande MA. PMID: 6236747.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    162. Endocarditis due to methicillin-resistant Staphylococcus aureus in rabbits: expression of resistance to beta-lactam antibiotics in vivo and in vitro. J Infect Dis. 1984 Jun; 149(6):894-903. Chambers HF, Hackbarth CJ, Drake TA, Rusnak MG, Sande MA. PMID: 6564133.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    163. Staphylococcus aureus endocarditis: clinical manifestations in addicts and nonaddicts. Medicine (Baltimore). 1983 May; 62(3):170-7. Chambers HF, Korzeniowski OM, Sande MA. PMID: 6843356.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
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