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Andrew Kerkhoff, MD, PhD

Title(s)CLINICAL FELLOW, Medicine
SchoolSchool of Medicine
Phone628-206-8492
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoFellowship2020Infectious Disease
    University of California, San FranciscoResidency2017Internal Medicine
    University of AmsterdamPhD2016Epidemiology
    The George Washington UniversityMD2015Medicine
    London School of Hygiene and Tropical MedicineMSc2010Control of Infectious Diseases
    The University of North Carolina at Chapel HillBA2008Music
    Collapse Awards and Honors
    CROI2013Young Investigator Award
    GWU2012  - 2015Lazarus Scholarship in Health Care Delivery
    UCSF2018ZSFG Department of Medicine Clinical Fellow Award

    Collapse Research 
    Collapse Research Activities and Funding
    Engagement and retention in tuberculosis care services among people living with HIV in Lusaka, Zambia: does gender matter?
    UCSF Center for AIDS Research, Mentored Scientist Award Sep 1, 2019 - Aug 31, 2020
    Role: Principle Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Barr DA , Lewis JM, Feasey N, Schutz C, Kerkhoff AD, Meintjes G, et al.Mycobacterium tuberculosis blood stream infection prevalence, diagnosis, and mortality risk in HIV-positive adults: a systematic review and meta-analysis of individual patient data. Lancet Infect Dis. 2020; In press.
    2. Sossen B, Broger T, Kerkhoff AD, Schutz C, Trollip A, Moreau E, Schumacher SG, Burton R, Ward A, Wilkinson RJ, Barr DA, Nicol MP, Denkinger CM, Meintjes G. 'SILVAMP TB LAM' rapid urine tuberculosis test predicts mortality in hospitalized HIV patients in South Africa. Clin Infect Dis. 2020 Jan 09. PMID: 31917832.
      View in: PubMed
    3. Kerkhoff AD, Rutishauser RL, Miller S, Babik JM. Clinical Utility of Universal Broad-Range PCR Amplicon Sequencing for Pathogen Identification: a retrospective cohort study. Clin Infect Dis. 2020 Jan 07. PMID: 31907545.
      View in: PubMed
    4. Broger T, Muyoyeta M, Kerkhoff AD, Denkinger CM, Moreau E. Tuberculosis test results using fresh versus biobanked urine samples with FujiLAM. Lancet Infect Dis. 2020 Jan; 20(1):22-23. PMID: 31876492.
      View in: PubMed
    5. Kerkhoff AD, Cattamanchi A.HIV and Tuberculosis: A Formidable Alliance. Diagnosis of HIV-associated tuberculosis. 2019; 127-159.
    6. Kerkhoff AD, Sossen B, Schutz C, Reipold EI, Trollip A, Moreau E, Schumacher SG, Burton R, Ward A, Nicol MP, Meintjes G, Denkinger CM, Broger T. Diagnostic sensitivity of SILVAMP TB-LAM (FujiLAM) point-of-care urine assay for extra-pulmonary tuberculosis in people living with HIV. Eur Respir J. 2019 Nov 07. PMID: 31699835.
      View in: PubMed
    7. Schutz C, Ward A, Burton R, Nicol MP, Blumenthal L, Meintjes G, Kerkhoff AD. False rifampicin resistant results using Xpert MTB/RIF on urine samples in hospitalised HIV-infected patients. South Afr J HIV Med. 2019; 20(1):978. PMID: 31534789.
      View in: PubMed
    8. Broger T, Sossen B, du Toit E, Kerkhoff AD, Schutz C, Ivanova Reipold E, Ward A, Barr DA, Macé A, Trollip A, Burton R, Ongarello S, Pinter A, Lowary TL, Boehme C, Nicol MP, Meintjes G, Denkinger CM. Novel lipoarabinomannan point-of-care tuberculosis test for people with HIV: a diagnostic accuracy study. Lancet Infect Dis. 2019 Aug; 19(8):852-861. PMID: 31155318.
      View in: PubMed
    9. Barr DA, Kerkhoff AD, Schutz C, Ward AM, Davies GR, Wilkinson RJ, Meintjes G. HIV-Associated Mycobacterium tuberculosis Bloodstream Infection Is Underdiagnosed by Single Blood Culture. J Clin Microbiol. 2018 05; 56(5). PMID: 29444831.
      View in: PubMed
    10. Gupta-Wright A, Kerkhoff AD, Meintjes G, Corbett EL. Urinary Lipoarabinomannan Detection and Disseminated Nontuberculous Mycobacterial Disease. Clin Infect Dis. 2018 01 06; 66(1):158. PMID: 29020175.
      View in: PubMed
    11. Kerkhoff AD, Patrick L, Cornett P, Kleinhenz ME, Brondfield S. Severe piperacillin-tazobactam-induced hemolysis in a cystic fibrosis patient. Clin Case Rep. 2017 12; 5(12):2059-2061. PMID: 29225856.
      View in: PubMed
    12. Kerkhoff AD, Barr DA, Schutz C, Burton R, Nicol MP, Lawn SD, Meintjes G. Disseminated tuberculosis among hospitalised HIV patients in South Africa: a common condition that can be rapidly diagnosed using urine-based assays. Sci Rep. 2017 09 07; 7(1):10931. PMID: 28883510.
      View in: PubMed
    13. Lawn SD, Kerkhoff AD, Burton R, Schutz C, Boulle A, Vogt M, Gupta-Wright A, Nicol MP, Meintjes G. Diagnostic accuracy, incremental yield and prognostic value of Determine TB-LAM for routine diagnostic testing for tuberculosis in HIV-infected patients requiring acute hospital admission in South Africa: a prospective cohort. BMC Med. 2017 03 21; 15(1):67. PMID: 28320384.
      View in: PubMed
    14. Kerkhoff AD, Lawn SD. A breakthrough urine-based diagnostic test for HIV-associated tuberculosis. Lancet. 2016 Mar 19; 387(10024):1139-41. PMID: 26970724.
      View in: PubMed
    15. Kerkhoff AD, Meintjes G, Opie J, Vogt M, Jhilmeet N, Wood R, Lawn SD. Anaemia in patients with HIV-associated TB: relative contributions of anaemia of chronic disease and iron deficiency. Int J Tuberc Lung Dis. 2016 Feb; 20(2):193-201. PMID: 26792471.
      View in: PubMed
    16. Meintjes G, Kerkhoff AD, Burton R, Schutz C, Boulle A, Van Wyk G, Blumenthal L, Nicol MP, Lawn SD. HIV-Related Medical Admissions to a South African District Hospital Remain Frequent Despite Effective Antiretroviral Therapy Scale-Up. Medicine (Baltimore). 2015 Dec; 94(50):e2269. PMID: 26683950.
      View in: PubMed
    17. Lawn SD, Kerkhoff AD. Rapid diagnosis of TB in HIV-positive in-patients with M. tuberculosis bacteraemia in sub-Saharan Africa. Int J Tuberc Lung Dis. 2015 Dec; 19(12):1557-9. PMID: 26614206.
      View in: PubMed
    18. Kerkhoff AD, Lawn SD, Schutz C, Burton R, Boulle A, Cobelens FJ, Meintjes G. Anemia, Blood Transfusion Requirements and Mortality Risk in Human Immunodeficiency Virus-Infected Adults Requiring Acute Medical Admission to Hospital in South Africa. Open Forum Infect Dis. 2015 Dec; 2(4):ofv173. PMID: 26730391.
      View in: PubMed
    19. Lawn SD, Kerkhoff AD, Burton R, Schutz C, van Wyk G, Vogt M, Pahlana P, Nicol MP, Meintjes G. Rapid microbiological screening for tuberculosis in HIV-positive patients on the first day of acute hospital admission by systematic testing of urine samples using Xpert MTB/RIF: a prospective cohort in South Africa. BMC Med. 2015 Aug 14; 13:192. PMID: 26275908.
      View in: PubMed
    20. Lawn SD, Kerkhoff AD, Nicol MP, Meintjes G. Underestimation of the True Specificity of the Urine Lipoarabinomannan Point-of-Care Diagnostic Assay for HIV-Associated Tuberculosis. J Acquir Immune Defic Syndr. 2015 Aug 01; 69(4):e144-6. PMID: 25961395.
      View in: PubMed
    21. Kerkhoff AD, Meintjes G, Burton R, Vogt M, Wood R, Lawn SD. Relationship Between Blood Concentrations of Hepcidin and Anemia Severity, Mycobacterial Burden, and Mortality Among Patients With HIV-Associated Tuberculosis. J Infect Dis. 2016 Jan 01; 213(1):61-70. PMID: 26136467.
      View in: PubMed
    22. Kerkhoff AD, Wood R, Cobelens FG, Gupta-Wright A, Bekker LG, Lawn SD. The predictive value of current haemoglobin levels for incident tuberculosis and/or mortality during long-term antiretroviral therapy in South Africa: a cohort study. BMC Med. 2015 Apr 02; 13:70. PMID: 25889688.
      View in: PubMed
    23. Kerkhoff AD, Lawn SD. Iron replacement therapy and anemia associated with chronic infectious diseases in sub-Saharan Africa. Clin Infect Dis. 2015 May 01; 60(9):1438-9. PMID: 25637588.
      View in: PubMed
    24. Kerkhoff AD, Wood R, Cobelens FG, Gupta-Wright A, Bekker LG, Lawn SD. Resolution of anaemia in a cohort of HIV-infected patients with a high prevalence and incidence of tuberculosis receiving antiretroviral therapy in South Africa. BMC Infect Dis. 2014 Dec 21; 14:3860. PMID: 25528467.
      View in: PubMed
    25. Andrew D. Kerkhoff, Juan A. Reyes, Afsoon D. Roberts, Gary L. Simon. A Rare Complication of Cytomegalovirus Infection. Infectious Diseases in Clinical Practice. 2014 Aug 1; 22(6):365-367.
      View in: Publisher Site
    26. Lawn SD, Kerkhoff AD, Burton R, Meintjes G. Underestimation of the incremental diagnostic yield of HIV-associated tuberculosis in studies of the Determine TB-LAM Ag urine assay. AIDS. 2014 Jul 31; 28(12):1846-8. PMID: 25006829.
      View in: PubMed
    27. Kerkhoff AD, Wood R, Vogt M, Lawn SD. Prognostic value of a quantitative analysis of lipoarabinomannan in urine from patients with HIV-associated tuberculosis. PLoS One. 2014; 9(7):e103285. PMID: 25075867.
      View in: PubMed
    28. Kerkhoff AD, Wood R, Vogt M, Lawn SD. Predictive value of anemia for tuberculosis in HIV-infected patients in Sub-Saharan Africa: an indication for routine microbiological investigation using new rapid assays. J Acquir Immune Defic Syndr. 2014 May 01; 66(1):33-40. PMID: 24346639.
      View in: PubMed
    29. Lawn SD, Kerkhoff AD, Wood R. In reply to 'C-reactive protein and tuberculosis screening: a new trick for an old dog?'. Int J Tuberc Lung Dis. 2013 Dec; 17(12):1657. PMID: 24200286.
      View in: PubMed
    30. Lawn SD, Kerkhoff AD, Vogt M, Wood R. HIV-associated tuberculosis: relationship between disease severity and the sensitivity of new sputum-based and urine-based diagnostic assays. BMC Med. 2013 Oct 29; 11:231. PMID: 24168211.
      View in: PubMed
    31. Lawn SD, Dheda K, Kerkhoff AD, Peter JG, Dorman S, Boehme CC, Nicol MP. Determine TB-LAM lateral flow urine antigen assay for HIV-associated tuberculosis: recommendations on the design and reporting of clinical studies. BMC Infect Dis. 2013 Sep 03; 13:407. PMID: 24004840.
      View in: PubMed
    32. Kerkhoff AD, Wood R, Lowe DM, Vogt M, Lawn SD. Blood neutrophil counts in HIV-infected patients with pulmonary tuberculosis: association with sputum mycobacterial load. PLoS One. 2013; 8(7):e67956. PMID: 23874476.
      View in: PubMed
    33. Kerkhoff AD, Gupta A, Samandari T, Lawn SD. The proportions of people living with HIV in low and middle-income countries who test tuberculin skin test positive using either a 5 mm or a 10 mm cut-off: a systematic review. BMC Infect Dis. 2013 Jul 08; 13:307. PMID: 23834892.
      View in: PubMed
    34. Lawn SD, Kerkhoff AD, Vogt M, Wood R. Diagnostic and prognostic value of serum C-reactive protein for screening for HIV-associated tuberculosis. Int J Tuberc Lung Dis. 2013 May; 17(5):636-43. PMID: 23575330.
      View in: PubMed
    35. Lawn SD, Kerkhoff AD. Serum C-reactive protein measurement for ruling out HIV-associated tuberculosis. Int J Tuberc Lung Dis. 2013 Feb; 17(2):283-4. PMID: 23317967.
      View in: PubMed
    36. Kerkhoff AD, Kranzer K, Samandari T, Nakiyingi-Miiro J, Whalen CC, Harries AD, Lawn SD. Systematic review of TST responses in people living with HIV in under-resourced settings: implications for isoniazid preventive therapy. PLoS One. 2012; 7(11):e49928. PMID: 23209621.
      View in: PubMed
    37. Lawn SD, Kerkhoff AD, Wood R.Reply to Boyles: testing for LAM in patients with advanced immunodeficiency in South Africa - much to gain and little to lose. AIDS. 2012; 17(26):2264-2265.
    38. Lawn SD, Kerkhoff AD, Wood R.Urine antigen test for diagnosis of HIV-associated tuberculosis- Authors’ reply. Lancet Infect Dis. 2012; 11(12):826-7.
    39. Lawn SD, Kerkhoff AD, Vogt M, Wood R. Clinical significance of lipoarabinomannan detection in urine using a low-cost point-of-care diagnostic assay for HIV-associated tuberculosis. AIDS. 2012 Aug 24; 26(13):1635-43. PMID: 22555166.
      View in: PubMed
    40. Lawn SD, Kerkhoff AD, Pahlana P, Vogt M, Wood R. Diagnostic yield of tuberculosis using sputum induction in HIV-positive patients before antiretroviral therapy. Int J Tuberc Lung Dis. 2012 Oct; 16(10):1354-7. PMID: 22862896.
      View in: PubMed
    41. Lawn SD, Kerkhoff AD, Wood R.Reply to Theron et al. Clin Infect Dis. 2012; 3(55):473-4.
    42. Lawn SD, Kerkhoff AD, Vogt M, Wood R. High diagnostic yield of tuberculosis from screening urine samples from HIV-infected patients with advanced immunodeficiency using the Xpert MTB/RIF assay. J Acquir Immune Defic Syndr. 2012 Jul 01; 60(3):289-94. PMID: 22531759.
      View in: PubMed
    43. Lawn SD, Kerkhoff AD, Wood R. Location of Xpert® MTB/RIF in centralised laboratories in South Africa undermines potential impact. Int J Tuberc Lung Dis. 2012 May; 16(5):701; author reply 702. PMID: 22507934.
      View in: PubMed
    44. Lawn SD, Kerkhoff AD, Vogt M, Ghebrekristos Y, Whitelaw A, Wood R. Characteristics and early outcomes of patients with Xpert MTB/RIF-negative pulmonary tuberculosis diagnosed during screening before antiretroviral therapy. Clin Infect Dis. 2012 Apr; 54(8):1071-9. PMID: 22318975.
      View in: PubMed
    45. Lawn SD, Kerkhoff AD, Wood R. Progression of subclinical culture-positive tuberculosis to symptomatic disease in HIV-infected individuals. AIDS. 2011 Nov 13; 25(17):2190-1. PMID: 22019818.
      View in: PubMed
    46. Lawn SD, Kerkhoff AD, Vogt M, Wood R. Diagnostic accuracy of a low-cost, urine antigen, point-of-care screening assay for HIV-associated pulmonary tuberculosis before antiretroviral therapy: a descriptive study. Lancet Infect Dis. 2012 Mar; 12(3):201-9. PMID: 22015305.
      View in: PubMed
    47. Kerkhoff AD, Wood R, Lawn SD. Optimum time to start antiretroviral therapy in patients with HIV-associated tuberculosis: before or after tuberculosis diagnosis? AIDS. 2011 Apr 24; 25(7):1003-6. PMID: 21346513.
      View in: PubMed
    48. Foster RD, Solberg TD, Li HS, Kerkhoff A, Enke CA, Willoughby TR, Kupelian PA. Comparison of transabdominal ultrasound and electromagnetic transponders for prostate localization. J Appl Clin Med Phys. 2010 Jan 06; 11(1):2924. PMID: 20160686.
      View in: PubMed
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