Brian Block, MD

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
Address505 Parnassus Avenue, #M1082
San Francisco CA 94117
Phone415-502-5126
PronounsHe/Him/His
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    Collapse Biography 
    Collapse education and training
    University of California, San Francisco, CAFellowship2019Pulmonary and Critical Care
    New York-Presbyterian Hospital, Columbia University, NYChief Resident2016Internal Medicine
    New York-Presbyterian Hospital, Columbia University, NYResidency2015Internal Medicine
    Harvard Medical School, Boston, MAMD2012
    Oberlin College, Oberlin, OHBA2006Biology
    University of California, San Francisco, CA2019Diversity, Equity, and Inclusion Champion Training
    Collapse awards and honors
    UCSF  - 2019Jeffrey Golden Outstanding Clinical Fellow Award
    UCSF  - 2019Innovations in Graduate Medical Education Award
    American College of Physicians  - 2016Herbert S. Waxman Scholarship Award for outstanding Chief Medical Residents
    Columbia University  - 2014Department of Medicine House Staff Award in Clinical Teaching
    Columbia University  - 2013Department of Medicine House Staff Award in Clinical Teaching
    Arnold P. Gold Foundation  - 2013Humanism and Excellence in Teaching Award
    Harvard Medical School  - 2010Dean’s Community Service Award
    Phi Beta Kappa  - 2006Member
    Oberlin College  - 2006Jason Chicoine Memorial Prize in Biology
    Oberlin College  - 2005Jason Chicoine Memorial Prize in Biology
    Oberlin College2002  - 2006John N. Stern Merit Scholarship in the Natural Sciences

    Collapse Overview 
    Collapse overview
    Brian Block is an Assistant Professor in the Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, the Associate Director of the Medical ICU, and the Associate Director of Critical Care Ultrasound at UCSF, and the Assistant Director of Critical Care Medicine for the Pulmonary Fellowship.

    Dr. Block has interests in medical ethics, communication, and decision-making during critical illness. He is also a recognized educator with experience developing and studying novel curricula. He sees patients in the UCSF General Pulmonary clinic and attends in the intensive care unit as well as the pulmonary function lab.

    Dr. Block graduated from Harvard Medical School, completed Internal Medicine training at Columbia University, and was also a Chief Medical Resident at Columbia. He then came to UCSF to complete fellowship training in Pulmonary and Critical Care medicine. During his research fellowship, he studied advance care planning among patients with critical illness. He also earned grant funding to study an intervention aimed at enhancing communication between general internists and medical subspecialty services, to improve teaching and patient care.

    Collapse Research 
    Collapse research activities and funding
    A Collaborative Workspace for Subspecialty Clinical Fellows
    University of California, San Francisco Innovations Funding for EducationJul 1, 2018 - Jun 30, 2019
    Role: Principal Investigator
    Description: Developing and coordinating study using mixed-methods (survey and focus groups) to understand how co-localizing medical subspecialty fellows and medicine residents impacts communication and teaching in the hospital.

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Should Artificial Intelligence Provide Input in End-of-Life Decision-Making?-Reply. JAMA Intern Med. 2025 Mar 01; 185(3):352. Brender TD, Smith AK, Block BL. PMID: 39761036.
      View in: PubMed   Mentions:    Fields:    
    2. Can Artificial Intelligence Speak for Incapacitated Patients at the End of Life? JAMA Intern Med. 2024 Sep 01; 184(9):1005-1006. Brender TD, Smith AK, Block BL. PMID: 39037787.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. It's All in the Timing. N Engl J Med. 2023 Sep 07; 389(10):940-947. Beagle AJ, Sunwoo BY, Olin RL, Schwartz BS, Block BL. PMID: 37672698.
      View in: PubMed   Mentions:    Fields:    
    4. Impact of a Multidisciplinary Post-COVID-19 Clinic on Hospital Admissions and ED Visits. Chest. 2023 07; 164(1):199-202. Levan S, Mourad M, Block B, Shah R, Santhosh L. PMID: 36610666; PMCID: PMC9811943.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    5. Response. Chest. 2022 01; 161(1):e63-e64. Santhosh L, Block B, Kim SY, Raju S, Shah RJ, Thakur N, Brigham EP, Parker AM. PMID: 35000721; PMCID: PMC8733311.
      View in: PubMed   Mentions: 1     Fields:    
    6. Building upon the foundational science curriculum with physiology-based grand rounds: a multi-institutional program evaluation. Med Educ Online. 2021 Dec; 26(1):1937908. Langer AL, Block BL, Schwartzstein RM, Richards JB. PMID: 34114945; PMCID: PMC8204959.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    7. A Woman with One Year of Cough Presumed to Be Asthma. Ann Am Thorac Soc. 2021 10; 18(10):1733-1737. Leba CT, Seeley EJ, Bhakta NR, Block BL. PMID: 34596494.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Variation in COVID-19 Mortality Across 117 US Hospitals in High- and Low-Burden Settings. J Hosp Med. 2021 04; 16(4):215-218. Block BL, Martin TM, Boscardin WJ, Covinsky KE, Mourad M, Hu LL, Smith AK. PMID: 33734977; PMCID: PMC8025591.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    9. Five things every clinician should know about AI ethics in intensive care. Intensive Care Med. 2021 02; 47(2):157-159. Shaw JA, Sethi N, Block BL. PMID: 33078241; PMCID: PMC7571864.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Restoring the Story and Creating a Valuable Clinical Note. Ann Intern Med. 2020 09 01; 173(5):380-382. Gantzer HE, Block BL, Hobgood LC, Tufte J. PMID: 32658567.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    11. Getting Neighborly in 2030: A Shared Fellow Workspace Improves Communication, Teaching, and Burnout. J Grad Med Educ. 2020 Jun; 12(3):358-360. Block BL, Anderson D, O'Brien B, Babik J. PMID: 32595866; PMCID: PMC7301954.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. During COVID-19, Outpatient Advance Care Planning Is Imperative: We Need All Hands on Deck. J Am Geriatr Soc. 2020 07; 68(7):1395-1397. Block BL, Smith AK, Sudore RL. PMID: 32359075; PMCID: PMC7267338.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCellsPHPublic Health
    13. Patterns and Trends in Advance Care Planning Among Older Adults Who Received Intensive Care at the End of Life. JAMA Intern Med. 2020 05 01; 180(5):786-789. Block BL, Jeon SY, Sudore RL, Matthay MA, Boscardin WJ, Smith AK. PMID: 32119031; PMCID: PMC7052782.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    14. Could Decisions to Limit Treatment Contribute to Mortality Differences between Patients with Different Presepsis Trajectories? Ann Am Thorac Soc. 2019 04; 16(4):522. Block BL, Matthay M. PMID: 30495973; PMCID: PMC6441695.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. The Journal of Law, Medicine & Ethics. Universal Advance Directives--Necessary but not Sufficient. 2019; 46(4):988-990. Brian L. Block, Alexander K. Smith, Rebecca L. Sudore. View Publication.
    16. Does the Term Intensive Care Unit Promote Aggressive Treatment? JAMA Intern Med. 2018 Dec 01; 178(12):1579-1580. Block BL. PMID: 30422219.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Two-Week Resident-As-Teacher Program May Improve Peer Feedback and Online Evaluation Completion. Medical Science Educator. 2018. Arielle L Langer, Samuel Bernard, Brian L Block. . View Publication.
    18. Unusual Radiographic Presentation of Pneumocystis Pneumonia in a Patient with AIDS. Case Rep Infect Dis. 2017; 2017:3183525. Block BL, Mehta T, Ortiz GM, Ferris SP, Vu TH, Huang L, Cattamanchi A. PMID: 29362681; PMCID: PMC5738569.
      View in: PubMed   Mentions: 7  
    19. Triple Oral Antithrombotic Therapy: A Teachable Moment. JAMA Intern Med. 2016 10 01; 176(10):1433-1434. Nouri SN, Block BL. PMID: 27532936.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Massive Rectal Hemorrhage After Prostate Biopsy: A Teachable Moment. JAMA Intern Med. 2016 08 01; 176(8):1064-5. Laracy JC, Regalbuto R, Block BL. PMID: 27322720.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Hypo-Hypo: A Complex Metabolic Disorder. Ann Am Thorac Soc. 2016 Jan; 13(1):127-33. Block BL, Bernard S, Schwartzstein RM. PMID: 26730868.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    22. Reduced replication capacity of NL4-3 recombinant viruses encoding reverse transcriptase-integrase sequences from HIV-1 elite controllers. J Acquir Immune Defic Syndr. 2011 Feb 01; 56(2):100-8. Brumme ZL, Li C, Miura T, Sela J, Rosato PC, Brumme CJ, Markle TJ, Martin E, Block BL, Trocha A, Kadie CM, Allen TM, Pereyra F, Heckerman D, Walker BD, Brockman MA. PMID: 21124229; PMCID: PMC3078702.
      View in: PubMed   Mentions: 34     Fields:    
    23. Using an agent-based model to analyze the dynamic communication network of the immune response. Theor Biol Med Model. 2011 Jan 19; 8:1. Folcik VA, Broderick G, Mohan S, Block B, Ekbote C, Doolittle J, Khoury M, Davis L, Marsh CB. PMID: 21247471; PMCID: PMC3032717.
      View in: PubMed   Mentions: 9     Fields:    
    24. The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science. 2010 Dec 10; 330(6010):1551-7. International HIV Controllers Study, Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, Plenge RM, Deeks SG, Gianniny L, Crawford G, Sullivan J, Gonzalez E, Davies L, Camargo A, Moore JM, Beattie N, Gupta S, Crenshaw A, Burtt NP, Guiducci C, Gupta N, Gao X, Qi Y, Yuki Y, Piechocka-Trocha A, Cutrell E, Rosenberg R, Moss KL, Lemay P, O'Leary J, Schaefer T, Verma P, Toth I, Block B, Baker B, Rothchild A, Lian J, Proudfoot J, Alvino DM, Vine S, Addo MM, Allen TM, Altfeld M, Henn MR, Le Gall S, Streeck H, Haas DW, Kuritzkes DR, Robbins GK, Shafer RW, Gulick RM, Shikuma CM, Haubrich R, Riddler S, Sax PE, Daar ES, Ribaudo HJ, Agan B, Agarwal S, Ahern RL, Allen BL, Altidor S, Altschuler EL, Ambardar S, Anastos K, Anderson B, Anderson V, Andrady U, Antoniskis D, Bangsberg D, Barbaro D, Barrie W, Bartczak J, Barton S, Basden P, Basgoz N, Bazner S, Bellos NC, Benson AM, Berger J, Bernard NF, Bernard AM, Birch C, Bodner SJ, Bolan RK, Boudreaux ET, Bradley M, Braun JF, Brndjar JE, Brown SJ, Brown K, Brown ST, Burack J, Bush LM, Cafaro V, Campbell O, Campbell J, Carlson RH, Carmichael JK, Casey KK, Cavacuiti C, Celestin G, Chambers ST, Chez N, Chirch LM, Cimoch PJ, Cohen D, Cohn LE, Conway B, Cooper DA, Cornelson B, Cox DT, Cristofano MV, Cuchural G, Czartoski JL, Dahman JM, Daly JS, Davis BT, Davis K, Davod SM, DeJesus E, Dietz CA, Dunham E, Dunn ME, Ellerin TB, Eron JJ, Fangman JJ, Farel CE, Ferlazzo H, Fidler S, Fleenor-Ford A, Frankel R, Freedberg KA, French NK, Fuchs JD, Fuller JD, Gaberman J, Gallant JE, Gandhi RT, Garcia E, Garmon D, Gathe JC, Gaultier CR, Gebre W, Gilman FD, Gilson I, Goepfert PA, Gottlieb MS, Goulston C, Groger RK, Gurley TD, Haber S, Hardwicke R, Hardy WD, Harrigan PR, Hawkins TN, Heath S, Hecht FM, Henry WK, Hladek M, Hoffman RP, Horton JM, Hsu RK, Huhn GD, Hunt P, Hupert MJ, Illeman ML, Jaeger H, Jellinger RM, John M, Johnson JA, Johnson KL, Johnson H, Johnson K, Joly J, Jordan WC, Kauffman CA, Khanlou H, Killian RK, Kim AY, Kim DD, Kinder CA, Kirchner JT, Kogelman L, Kojic EM, Korthuis PT, Kurisu W, Kwon DS, LaMar M, Lampiris H, Lanzafame M, Lederman MM, Lee DM, Lee JM, Lee MJ, Lee ET, Lemoine J, Levy JA, Llibre JM, Liguori MA, Little SJ, Liu AY, Lopez AJ, Loutfy MR, Loy D, Mohammed DY, Man A, Mansour MK, Marconi VC, Markowitz M, Marques R, Martin JN, Martin HL, Mayer KH, McElrath MJ, McGhee TA, McGovern BH, McGowan K, McIntyre D, Mcleod GX, Menezes P, Mesa G, Metroka CE, Meyer-Olson D, Miller AO, Montgomery K, Mounzer KC, Nagami EH, Nagin I, Nahass RG, Nelson MO, Nielsen C, Norene DL, O'Connor DH, Ojikutu BO, Okulicz J, Oladehin OO, Oldfield EC, Olender SA, Ostrowski M, Owen WF, Pae E, Parsonnet J, Pavlatos AM, Perlmutter AM, Pierce MN, Pincus JM, Pisani L, Price LJ, Proia L, Prokesch RC, Pujet HC, Ramgopal M, Rathod A, Rausch M, Ravishankar J, Rhame FS, Richards CS, Richman DD, Rodes B, Rodriguez M, Rose RC, Rosenberg ES, Rosenthal D, Ross PE, Rubin DS, Rumbaugh E, Saenz L, Salvaggio MR, Sanchez WC, Sanjana VM, Santiago S, Schmidt W, Schuitemaker H, Sestak PM, Shalit P, Shay W, Shirvani VN, Silebi VI, Sizemore JM, Skolnik PR, Sokol-Anderson M, Sosman JM, Stabile P, Stapleton JT, Starrett S, Stein F, Stellbrink HJ, Sterman FL, Stone VE, Stone DR, Tambussi G, Taplitz RA, Tedaldi EM, Telenti A, et al. PMID: 21051598; PMCID: PMC3235490.
      View in: PubMed   Mentions: 583     Fields:    
    25. Impaired replication capacity of acute/early viruses in persons who become HIV controllers. J Virol. 2010 Aug; 84(15):7581-91. Miura T, Brumme ZL, Brockman MA, Rosato P, Sela J, Brumme CJ, Pereyra F, Kaufmann DE, Trocha A, Block BL, Daar ES, Connick E, Jessen H, Kelleher AD, Rosenberg E, Markowitz M, Schafer K, Vaida F, Iwamoto A, Little S, Walker BD. PMID: 20504921; PMCID: PMC2897600.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    26. Persistent low-level viremia in HIV-1 elite controllers and relationship to immunologic parameters. J Infect Dis. 2009 Sep 15; 200(6):984-90. Pereyra F, Palmer S, Miura T, Block BL, Wiegand A, Rothchild AC, Baker B, Rosenberg R, Cutrell E, Seaman MS, Coffin JM, Walker BD. PMID: 19656066; PMCID: PMC3725728.
      View in: PubMed   Mentions: 121     Fields:    Translation:HumansCells
    27. Rapid HIV testing program implementation: lessons from the emergency department. Int J Emerg Med. 2009 Sep 01; 2(3):187-94. Arbelaez C, Block B, Losina E, Wright EA, Reichmann WM, Mikulinsky R, Solomon JD, Dooley MM, Walensky RP. PMID: 20157472; PMCID: PMC2760703.
      View in: PubMed   Mentions: 5  
    28. Differential neutralization of human immunodeficiency virus (HIV) replication in autologous CD4 T cells by HIV-specific cytotoxic T lymphocytes. J Virol. 2009 Apr; 83(7):3138-49. Chen H, Piechocka-Trocha A, Miura T, Brockman MA, Julg BD, Baker BM, Rothchild AC, Block BL, Schneidewind A, Koibuchi T, Pereyra F, Allen TM, Walker BD. PMID: 19158248; PMCID: PMC2655558.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    29. HLA-associated viral mutations are common in human immunodeficiency virus type 1 elite controllers. J Virol. 2009 Apr; 83(7):3407-12. Miura T, Brumme CJ, Brockman MA, Brumme ZL, Pereyra F, Block BL, Trocha A, John M, Mallal S, Harrigan PR, Walker BD. PMID: 19153230; PMCID: PMC2655568.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    30. HLA-B57/B*5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte [corrected] recognition. J Virol. 2009 Mar; 83(6):2743-55. Miura T, Brockman MA, Schneidewind A, Lobritz M, Pereyra F, Rathod A, Block BL, Brumme ZL, Brumme CJ, Baker B, Rothchild AC, Li B, Trocha A, Cutrell E, Frahm N, Brander C, Toth I, Arts EJ, Allen TM, Walker BD. PMID: 19116253; PMCID: PMC2648254.
      View in: PubMed   Mentions: 148     Fields:    Translation:HumansCells
    31. HLA-associated alterations in replication capacity of chimeric NL4-3 viruses carrying gag-protease from elite controllers of human immunodeficiency virus type 1. J Virol. 2009 Jan; 83(1):140-9. Miura T, Brockman MA, Brumme ZL, Brumme CJ, Pereyra F, Trocha A, Block BL, Schneidewind A, Allen TM, Heckerman D, Walker BD. PMID: 18971283; PMCID: PMC2612337.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    32. Revising expectations from rapid HIV tests in the emergency department. Ann Intern Med. 2008 Aug 05; 149(3):153-60. Walensky RP, Arbelaez C, Reichmann WM, Walls RM, Katz JN, Block BL, Dooley M, Hetland A, Kimmel S, Solomon JD, Losina E. PMID: 18678842; PMCID: PMC3260470.
      View in: PubMed   Mentions: 27     Fields:    
    33. Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection. J Virol. 2008 Sep; 82(18):9216-27. Brumme ZL, Brumme CJ, Carlson J, Streeck H, John M, Eichbaum Q, Block BL, Baker B, Kadie C, Markowitz M, Jessen H, Kelleher AD, Rosenberg E, Kaldor J, Yuki Y, Carrington M, Allen TM, Mallal S, Altfeld M, Heckerman D, Walker BD. PMID: 18614631; PMCID: PMC2546878.
      View in: PubMed   Mentions: 76     Fields:    
    34. Genetic characterization of human immunodeficiency virus type 1 in elite controllers: lack of gross genetic defects or common amino acid changes. J Virol. 2008 Sep; 82(17):8422-30. Miura T, Brockman MA, Brumme CJ, Brumme ZL, Carlson JM, Pereyra F, Trocha A, Addo MM, Block BL, Rothchild AC, Baker BM, Flynn T, Schneidewind A, Li B, Wang YE, Heckerman D, Allen TM, Walker BD. PMID: 18562530; PMCID: PMC2519665.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    35. Combined N- and C-terminal truncation of human apolipoprotein A-I yields a folded, functional central domain. Biochemistry. 2005 Mar 22; 44(11):4591-9. Beckstead JA, Block BL, Bielicki JK, Kay CM, Oda MN, Ryan RO. PMID: 15766290.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
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