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Brian Block, MD

Title(s)Clinical Instructor, Medicine
SchoolSchool of Medicine
Phone415-476-0735
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Francisco, CAFellowship2019Pulmonary and Critical Care
    New York-Presbyterian Hospital, Columbia University, NYChief Resident2016Internal Medicine
    New York-Presbyterian Hospital, Columbia University, NYResidency2015Internal Medicine
    Harvard Medical School, Boston, MAMD2012
    Oberlin College, Oberlin, OHBA2006Biology
    Collapse Awards and Honors
    UCSF  - 2019Jeffrey Golden Outstanding Clinical Fellow Award
    UCSF  - 2019Innovations in Graduate Medical Education Award
    American College of Physicians  - 2016Herbert S. Waxman Scholarship Award for outstanding Chief Medical Residents
    Columbia University  - 2014Department of Medicine House Staff Award in Clinical Teaching
    Columbia University  - 2013Department of Medicine House Staff Award in Clinical Teaching
    Arnold P. Gold Foundation  - 2013Humanism and Excellence in Teaching Award
    Harvard Medical School  - 2010Dean’s Community Service Award
    Phi Beta Kappa  - 2006Member
    Oberlin College  - 2006Jason Chicoine Memorial Prize in Biology
    Oberlin College  - 2005Jason Chicoine Memorial Prize in Biology
    Oberlin College2002  - 2006John N. Stern Merit Scholarship in the Natural Sciences

    Collapse Overview 
    Collapse Overview
    Brian Block is an Instructor of Medicine in the Division of Pulmonary and Critical Care and Research Fellow with interests in medical ethics, physician-patient communication, physician-physician communication, and decision-making during critical illness. He is also an award-winning medical educator with experience developing and studying novel educational curricula.

    Dr. Block graduated from Harvard Medical School, completed Internal Medicine training at Columbia University, and was also a Chief Medical Resident at Columbia. He then came to UCSF to complete fellowship training in Pulmonary and Critical Care medicine. At present, he is working to improve our understanding of how patients and families prepare for and make difficult decisions in the intensive care unit, with a view towards providing more support for those who face difficult choices with uncertain outcomes. He also earned grant funding to study an intervention aimed at enhancing communication between general internists and medical subspecialty services, to improve teaching and patient care.

    Dr. Block holds an elected position with the American College of Physician's Council of Resident/Fellow members, and is on the ACP's Education Committee and Restoring the Story TaskForce. He won the 2019 UCSF Innovations in Graduate Medical Education award for these national efforts and his local work to improve education at UCSF.

    Collapse Research 
    Collapse Research Activities and Funding
    A Collaborative Workspace for Subspecialty Clinical Fellows
    University of California, San Francisco Innovations Funding for EducationJul 1, 2018 - Jun 30, 2019
    Role: Principal Investigator
    Role Description: Developing and coordinating study using mixed-methods (survey and focus groups) to understand how co-localizing medical subspecialty fellows and medicine residents impacts communication and teaching in the hospital.

    Collapse ORNG Applications 
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Block BL, Matthay M. Could Decisions to Limit Treatment Contribute to Mortality Differences between Patients with Different Presepsis Trajectories? Ann Am Thorac Soc. 2019 Apr; 16(4):522. PMID: 30495973.
      View in: PubMed
    2. Brian L. Block, Alexander K. Smith, Rebecca L. Sudore.The Journal of Law, Medicine & Ethics. Universal Advance Directives--Necessary but not Sufficient. 2019; 46(4):988-990.
      View Publication
    3. Block BL. Does the Term Intensive Care Unit Promote Aggressive Treatment? JAMA Intern Med. 2018 Dec 01; 178(12):1579-1580. PMID: 30422219.
      View in: PubMed
    4. Arielle L Langer, Samuel Bernard, Brian L Block.. Two-Week Resident-As-Teacher Program May Improve Peer Feedback and Online Evaluation Completion. Medical Science Educator. 2018.
      View Publication
    5. Block BL, Mehta T, Ortiz GM, Ferris SP, Vu TH, Huang L, Cattamanchi A. Unusual Radiographic Presentation of Pneumocystis Pneumonia in a Patient with AIDS. Case Rep Infect Dis. 2017; 2017:3183525. PMID: 29362681.
      View in: PubMed
    6. Nouri SN, Block BL. Triple Oral Antithrombotic Therapy: A Teachable Moment. JAMA Intern Med. 2016 10 01; 176(10):1433-1434. PMID: 27532936.
      View in: PubMed
    7. Laracy JC, Regalbuto R, Block BL. Massive Rectal Hemorrhage After Prostate Biopsy: A Teachable Moment. JAMA Intern Med. 2016 08 01; 176(8):1064-5. PMID: 27322720.
      View in: PubMed
    8. Block BL, Bernard S, Schwartzstein RM. Hypo-Hypo: A Complex Metabolic Disorder. Ann Am Thorac Soc. 2016 Jan; 13(1):127-33. PMID: 26730868.
      View in: PubMed
    9. Brumme ZL, Li C, Miura T, Sela J, Rosato PC, Brumme CJ, Markle TJ, Martin E, Block BL, Trocha A, Kadie CM, Allen TM, Pereyra F, Heckerman D, Walker BD, Brockman MA. Reduced replication capacity of NL4-3 recombinant viruses encoding reverse transcriptase-integrase sequences from HIV-1 elite controllers. J Acquir Immune Defic Syndr. 2011 Feb 01; 56(2):100-8. PMID: 21124229.
      View in: PubMed
    10. Folcik VA, Broderick G, Mohan S, Block B, Ekbote C, Doolittle J, Khoury M, Davis L, Marsh CB. Using an agent-based model to analyze the dynamic communication network of the immune response. Theor Biol Med Model. 2011 Jan 19; 8:1. PMID: 21247471.
      View in: PubMed
    11. Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, Plenge RM, Deeks SG, Gianniny L, Crawford G, Sullivan J, Gonzalez E, Davies L, Camargo A, Moore JM, Beattie N, Gupta S, Crenshaw A, Burtt NP, Guiducci C, Gupta N, Gao X, Qi Y, Yuki Y, Piechocka-Trocha A, Cutrell E, Rosenberg R, Moss KL, Lemay P, O'Leary J, Schaefer T, Verma P, Toth I, Block B, Baker B, Rothchild A, Lian J, Proudfoot J, Alvino DM, Vine S, Addo MM, Allen TM, Altfeld M, Henn MR, Le Gall S, Streeck H, Haas DW, Kuritzkes DR, Robbins GK, Shafer RW, Gulick RM, Shikuma CM, Haubrich R, Riddler S, Sax PE, Daar ES, Ribaudo HJ, Agan B, Agarwal S, Ahern RL, Allen BL, Altidor S, Altschuler EL, Ambardar S, Anastos K, Anderson B, Anderson V, Andrady U, Antoniskis D, Bangsberg D, Barbaro D, Barrie W, Bartczak J, Barton S, Basden P, Basgoz N, Bazner S, Bellos NC, Benson AM, Berger J, Bernard NF, Bernard AM, Birch C, Bodner SJ, Bolan RK, Boudreaux ET, Bradley M, Braun JF, Brndjar JE, Brown SJ, Brown K, Brown ST, Burack J, Bush LM, Cafaro V, Campbell O, Campbell J, Carlson RH, Carmichael JK, Casey KK, Cavacuiti C, Celestin G, Chambers ST, Chez N, Chirch LM, Cimoch PJ, Cohen D, Cohn LE, Conway B, Cooper DA, Cornelson B, Cox DT, Cristofano MV, Cuchural G, Czartoski JL, Dahman JM, Daly JS, Davis BT, Davis K, Davod SM, DeJesus E, Dietz CA, Dunham E, Dunn ME, Ellerin TB, Eron JJ, Fangman JJ, Farel CE, Ferlazzo H, Fidler S, Fleenor-Ford A, Frankel R, Freedberg KA, French NK, Fuchs JD, Fuller JD, Gaberman J, Gallant JE, Gandhi RT, Garcia E, Garmon D, Gathe JC, Gaultier CR, Gebre W, Gilman FD, Gilson I, Goepfert PA, Gottlieb MS, Goulston C, Groger RK, Gurley TD, Haber S, Hardwicke R, Hardy WD, Harrigan PR, Hawkins TN, Heath S, Hecht FM, Henry WK, Hladek M, Hoffman RP, Horton JM, Hsu RK, Huhn GD, Hunt P, Hupert MJ, Illeman ML, Jaeger H, Jellinger RM, John M, Johnson JA, Johnson KL, Johnson H, Johnson K, Joly J, Jordan WC, Kauffman CA, Khanlou H, Killian RK, Kim AY, Kim DD, Kinder CA, Kirchner JT, Kogelman L, Kojic EM, Korthuis PT, Kurisu W, Kwon DS, LaMar M, Lampiris H, Lanzafame M, Lederman MM, Lee DM, Lee JM, Lee MJ, Lee ET, Lemoine J, Levy JA, Llibre JM, Liguori MA, Little SJ, Liu AY, Lopez AJ, Loutfy MR, Loy D, Mohammed DY, Man A, Mansour MK, Marconi VC, Markowitz M, Marques R, Martin JN, Martin HL, Mayer KH, McElrath MJ, McGhee TA, McGovern BH, McGowan K, McIntyre D, Mcleod GX, Menezes P, Mesa G, Metroka CE, Meyer-Olson D, Miller AO, Montgomery K, Mounzer KC, Nagami EH, Nagin I, Nahass RG, Nelson MO, Nielsen C, Norene DL, O'Connor DH, Ojikutu BO, Okulicz J, Oladehin OO, Oldfield EC, Olender SA, Ostrowski M, Owen WF, Pae E, Parsonnet J, Pavlatos AM, Perlmutter AM, Pierce MN, Pincus JM, Pisani L, Price LJ, Proia L, Prokesch RC, Pujet HC, Ramgopal M, Rathod A, Rausch M, Ravishankar J, Rhame FS, Richards CS, Richman DD, Rodes B, Rodriguez M, Rose RC, Rosenberg ES, Rosenthal D, Ross PE, Rubin DS, Rumbaugh E, Saenz L, Salvaggio MR, Sanchez WC, Sanjana VM, Santiago S, Schmidt W, Schuitemaker H, Sestak PM, Shalit P, Shay W, Shirvani VN, Silebi VI, Sizemore JM, Skolnik PR, Sokol-Anderson M, Sosman JM, Stabile P, Stapleton JT, Starrett S, Stein F, Stellbrink HJ, Sterman FL, Stone VE, Stone DR, Tambussi G, Taplitz RA, Tedaldi EM, Telenti A, Theisen W, Torres R, Tosiello L, Tremblay C, Tribble MA, Trinh PD, Tsao A, Ueda P, Vaccaro A, Valadas E, Vanig TJ, Vecino I, Vega VM, Veikley W, Wade BH, Walworth C, Wanidworanun C, Ward DJ, Warner DA, Weber RD, Webster D, Weis S, Wheeler DA, White DJ, Wilkins E, Winston A, Wlodaver CG, van't Wout A, Wright DP, Yang OO, Yurdin DL, Zabukovic BW, Zachary KC, Zeeman B, Zhao M. The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science. 2010 Dec 10; 330(6010):1551-7. PMID: 21051598.
      View in: PubMed
    12. Miura T, Brumme ZL, Brockman MA, Rosato P, Sela J, Brumme CJ, Pereyra F, Kaufmann DE, Trocha A, Block BL, Daar ES, Connick E, Jessen H, Kelleher AD, Rosenberg E, Markowitz M, Schafer K, Vaida F, Iwamoto A, Little S, Walker BD. Impaired replication capacity of acute/early viruses in persons who become HIV controllers. J Virol. 2010 Aug; 84(15):7581-91. PMID: 20504921.
      View in: PubMed
    13. Pereyra F, Palmer S, Miura T, Block BL, Wiegand A, Rothchild AC, Baker B, Rosenberg R, Cutrell E, Seaman MS, Coffin JM, Walker BD. Persistent low-level viremia in HIV-1 elite controllers and relationship to immunologic parameters. J Infect Dis. 2009 Sep 15; 200(6):984-90. PMID: 19656066.
      View in: PubMed
    14. Arbelaez C, Block B, Losina E, Wright EA, Reichmann WM, Mikulinsky R, Solomon JD, Dooley MM, Walensky RP. Rapid HIV testing program implementation: lessons from the emergency department. Int J Emerg Med. 2009 Sep 01; 2(3):187-94. PMID: 20157472.
      View in: PubMed
    15. Chen H, Piechocka-Trocha A, Miura T, Brockman MA, Julg BD, Baker BM, Rothchild AC, Block BL, Schneidewind A, Koibuchi T, Pereyra F, Allen TM, Walker BD. Differential neutralization of human immunodeficiency virus (HIV) replication in autologous CD4 T cells by HIV-specific cytotoxic T lymphocytes. J Virol. 2009 Apr; 83(7):3138-49. PMID: 19158248.
      View in: PubMed
    16. Miura T, Brumme CJ, Brockman MA, Brumme ZL, Pereyra F, Block BL, Trocha A, John M, Mallal S, Harrigan PR, Walker BD. HLA-associated viral mutations are common in human immunodeficiency virus type 1 elite controllers. J Virol. 2009 Apr; 83(7):3407-12. PMID: 19153230.
      View in: PubMed
    17. Miura T, Brockman MA, Schneidewind A, Lobritz M, Pereyra F, Rathod A, Block BL, Brumme ZL, Brumme CJ, Baker B, Rothchild AC, Li B, Trocha A, Cutrell E, Frahm N, Brander C, Toth I, Arts EJ, Allen TM, Walker BD. HLA-B57/B*5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte [corrected] recognition. J Virol. 2009 Mar; 83(6):2743-55. PMID: 19116253.
      View in: PubMed
    18. Miura T, Brockman MA, Brumme ZL, Brumme CJ, Pereyra F, Trocha A, Block BL, Schneidewind A, Allen TM, Heckerman D, Walker BD. HLA-associated alterations in replication capacity of chimeric NL4-3 viruses carrying gag-protease from elite controllers of human immunodeficiency virus type 1. J Virol. 2009 Jan; 83(1):140-9. PMID: 18971283.
      View in: PubMed
    19. Walensky RP, Arbelaez C, Reichmann WM, Walls RM, Katz JN, Block BL, Dooley M, Hetland A, Kimmel S, Solomon JD, Losina E. Revising expectations from rapid HIV tests in the emergency department. Ann Intern Med. 2008 Aug 05; 149(3):153-60. PMID: 18678842.
      View in: PubMed
    20. Brumme ZL, Brumme CJ, Carlson J, Streeck H, John M, Eichbaum Q, Block BL, Baker B, Kadie C, Markowitz M, Jessen H, Kelleher AD, Rosenberg E, Kaldor J, Yuki Y, Carrington M, Allen TM, Mallal S, Altfeld M, Heckerman D, Walker BD. Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection. J Virol. 2008 Sep; 82(18):9216-27. PMID: 18614631.
      View in: PubMed
    21. Miura T, Brockman MA, Brumme CJ, Brumme ZL, Carlson JM, Pereyra F, Trocha A, Addo MM, Block BL, Rothchild AC, Baker BM, Flynn T, Schneidewind A, Li B, Wang YE, Heckerman D, Allen TM, Walker BD. Genetic characterization of human immunodeficiency virus type 1 in elite controllers: lack of gross genetic defects or common amino acid changes. J Virol. 2008 Sep; 82(17):8422-30. PMID: 18562530.
      View in: PubMed
    22. Beckstead JA, Block BL, Bielicki JK, Kay CM, Oda MN, Ryan RO. Combined N- and C-terminal truncation of human apolipoprotein A-I yields a folded, functional central domain. Biochemistry. 2005 Mar 22; 44(11):4591-9. PMID: 15766290.
      View in: PubMed
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