Burt Feuerstein, MD, PhD

Title(s)Professor Emeritus, Laboratory Medicine
SchoolSchool of Medicine
Address3333 California Street
San Francisco CA 94118
Phone--
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency 1982Pediatrics
    University of California, San FranciscoFellowship1985Pediatric Hematology/Oncology
    University at Buffalo, SUNYMD and PhD1979Medicine and Pharmacology
    Wesleyan University, Middletown CTBA1972Music

    Collapse Overview 
    Collapse Overview
    Dr. Burt Feuerstein grew up in Buffalo, NY, and graduated from Wesleyan University with a BA in music (1972), and from the University at Buffalo School of Medicine and Dentistry/Roswell Park Cancer Institute with an MD and PhD in pharmacology (1979). He completed his residency in
    Pediatrics and fellowship in Pediatric Hematology/Oncology at the University of California San Francisco, was professor of Lab Medicine and Neurological Surgery at UCSF, and is emeritus since 2006. Burt moved to Barrow Neurological Institute in 2006, and joined the University of Arizona College of Medicine – Phoenix in 2010. He is Professor of Child Health and Neurology, and retired in 2018. His present academic interests include drug development, brain tumor diagnosis and therapy, medical ethics in human research, and mentoring.

    PATENT INFORMATION for Dr. Burt Feuerstein:

    Therapeutic polyamines
    Inventors: Basu; Hirak S. (Pacifica, CA), Feuerstein; Burt (San Francisco, CA), Marton; Laurence (Fitchburg, WI), Samejima; Keijiro (Kokubunji, Tokyo 185, JP)
    Family ID: 22521929
    Appl. No.: 08/147,527
    Filed: November 5, 1993

    Therapeutic polyamines
    Inventors: Feuerstein; Burt G. (San Francisco, CA), Mohapatra; Gayatry (San Francisco, CA), Kim; Dong H. (San Francisco, CA)
    Assignee: The Regents of the University of California (Oakland, CA)
    Family ID: 23595852
    Appl. No.: 08/403,457
    Filed: March 14, 1995

    Genetic gain and loss in gliomas
    Inventors: Feuerstein; Burt G. (San Francisco, CA), Mohapatra; Gayatry (San Francisco, CA), Kim; Dong H. (San Francisco, CA)
    Assignee: The Regents of the University of California (Oakland, CA)
    Family ID: 23595852
    Appl. No.: 08/403,457
    Filed: March 14, 1995

    Glioma-associated nucleic acid probes
    Inventors: Feuerstein; Burt G. (San Francisco, CA), Mohapatra; Gayatry (San Francisco, CA), Kim; Dong Hyung (San Francisco, CA)
    Assignee: The Regents of the University of California (Oakland, CA)
    Family ID: 23595852
    Appl. No.: 08/812,609
    Filed: March 6, 1997

    Collapse Research 
    Collapse Research Activities and Funding
    MOLECULAR CYTOGENETIC MARKERS IN GLIOMA PROGNOSIS
    NIH/NCI R01CA061147Aug 1, 1994 - Jun 30, 1998
    Role: Principal Investigator
    RATIONAL DEVELOPMENT OF POLYAMINE ANALOGUES
    NIH/NCI R29CA041757Dec 1, 1986 - Nov 30, 1991
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Provision of rapid and specific ex vivo diagnosis of central nervous system lymphoma from rodent xenograft biopsies by a fluorescent aptamer. J Neurosurg. 2020 07 24; 134(6):1783-1790. Georges J, Qi X, Liu X, Zhou Y, Woolf EC, Valeri A, Al-Atrache Z, Belykh E, Feuerstein BG, Preul M, Scheck AC, Reiser M, Anderson T, Gopez J, Appelt D, Yocom S, Eschbacher J, Yan H, Nakaji P. PMID: 32707545.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    2. Handheld confocal laser endomicroscopic imaging utilizing tumor-specific fluorescent labeling to identify experimental glioma cells in vivo. Surg Neurol Int. 2016; 7(Suppl 40):S995-S1003. Martirosyan NL, Georges J, Kalani MY, Nakaji P, Spetzler RF, Feuerstein BG, Preul MC. PMID: 28144472; PMCID: PMC5234279.
      View in: PubMed   Mentions: 8  
    3. The role of AKT isoforms in glioblastoma: AKT3 delays tumor progression. J Neurooncol. 2016 10; 130(1):43-52. Joy A, Kapoor M, Georges J, Butler L, Chang Y, Li C, Crouch A, Smirnov I, Nakada M, Hepler J, Marty M, Feuerstein BG. PMID: 27422127; PMCID: PMC5071179.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    4. Use of a conformational switching aptamer for rapid and specific ex vivo identification of central nervous system lymphoma in a xenograft model. PLoS One. 2015; 10(4):e0123607. Georges JF, Liu X, Eschbacher J, Nichols J, Mooney MA, Joy A, Spetzler RF, Feuerstein BG, Preul MC, Anderson T, Yan H, Nakaji P. PMID: 25876071; PMCID: PMC4398547.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    5. Clinicopathologic features of pediatric oligodendrogliomas: a series of 50 patients. Am J Surg Pathol. 2014 Aug; 38(8):1058-70. Rodriguez FJ, Tihan T, Lin D, McDonald W, Nigro J, Feuerstein B, Jackson S, Cohen K, Burger PC. PMID: 24805856; PMCID: PMC4322928.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    6. AKT pathway genes define 5 prognostic subgroups in glioblastoma. PLoS One. 2014; 9(7):e100827. Joy A, Ramesh A, Smirnov I, Reiser M, Misra A, Shapiro WR, Mills GB, Kim S, Feuerstein BG. PMID: 24984002; PMCID: PMC4077731.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    7. Sulforhodamine 101 selectively labels human astrocytoma cells in an animal model of glioblastoma. J Clin Neurosci. 2014 May; 21(5):846-51. Georges JF, Martirosyan NL, Eschbacher J, Nichols J, Tissot M, Preul MC, Feuerstein B, Anderson T, Spetzler RF, Nakaji P. PMID: 24666692.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    8. Label-free microscopic assessment of glioblastoma biopsy specimens prior to biobanking [corrected]. Neurosurg Focus. 2014 Feb; 36(2):E8. Georges J, Zehri A, Carlson E, Nichols J, Mooney MA, Martirosyan NL, Ghaffari L, Kalani MY, Eschbacher J, Feuerstein B, Anderson T, Preul MC, Van Keuren-Jensen K, Nakaji P. PMID: 24484261.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    9. Molecular interactions of ErbB1 (EGFR) and integrin-β1 in astrocytoma frozen sections predict clinical outcome and correlate with Akt-mediated in vitro radioresistance. Neuro Oncol. 2013 Aug; 15(8):1027-40. Petrás M, Lajtos T, Friedländer E, Klekner A, Pintye E, Feuerstein BG, Szöllosi J, Vereb G. PMID: 23595626; PMCID: PMC3714153.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    10. Intraoperative fluorescent imaging of intracranial tumors: a review. Clin Neurol Neurosurg. 2013 May; 115(5):517-28. Behbahaninia M, Martirosyan NL, Georges J, Udovich JA, Kalani MY, Feuerstein BG, Nakaji P, Spetzler RF, Preul MC. PMID: 23523009.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    11. DNA copy number alterations in central primitive neuroectodermal tumors and tumors of the pineal region: an international individual patient data meta-analysis. J Neurooncol. 2012 Sep; 109(2):415-23. von Bueren AO, Gerss J, Hagel C, Cai H, Remke M, Hasselblatt M, Feuerstein BG, Pernet S, Delattre O, Korshunov A, Rutkowski S, Pfister SM, Baudis M. PMID: 22772606.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    12. Reevaluating the imaging definition of tumor progression: perfusion MRI quantifies recurrent glioblastoma tumor fraction, pseudoprogression, and radiation necrosis to predict survival. Neuro Oncol. 2012 Jul; 14(7):919-30. Hu LS, Eschbacher JM, Heiserman JE, Dueck AC, Shapiro WR, Liu S, Karis JP, Smith KA, Coons SW, Nakaji P, Spetzler RF, Feuerstein BG, Debbins J, Baxter LC. PMID: 22561797; PMCID: PMC3379799.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansPHPublic Health
    13. The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence. Neuro Oncol. 2011 Jul; 13(7):736-47. Lambiv WL, Vassallo I, Delorenzi M, Shay T, Diserens AC, Misra A, Feuerstein B, Murat A, Migliavacca E, Hamou MF, Sciuscio D, Burger R, Domany E, Stupp R, Hegi ME. PMID: 21642372; PMCID: PMC3129269.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    14. Pituicytoma: characterization of a unique neoplasm by histology, immunohistochemistry, ultrastructure, and array-based comparative genomic hybridization. Arch Pathol Lab Med. 2010 Jul; 134(7):1063-9. Phillips JJ, Misra A, Feuerstein BG, Kunwar S, Tihan T. PMID: 20586639; PMCID: PMC3161118.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    15. A multigene predictor of outcome in glioblastoma. Neuro Oncol. 2010 Jan; 12(1):49-57. Colman H, Zhang L, Sulman EP, McDonald JM, Shooshtari NL, Rivera A, Popoff S, Nutt CL, Louis DN, Cairncross JG, Gilbert MR, Phillips HS, Mehta MP, Chakravarti A, Pelloski CE, Bhat K, Feuerstein BG, Jenkins RB, Aldape K. PMID: 20150367; PMCID: PMC2940562.
      View in: PubMed   Mentions: 184     Fields:    Translation:Humans
    16. Amplifying small amounts of tumor DNA allows detection of DNA copy number abberations with array-CGH. Biotechniques. 2008 Jun; 44(7):Piii-Pvi. Prestegarden L, Misra A, Ware ML, Yeh RF, Bjerkvig R, Feuerstein BG. PMID: 18533897.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    17. Functional inactivation of the KLF6 tumor suppressor gene by loss of heterozygosity and increased alternative splicing in glioblastoma. Int J Cancer. 2007 Sep 15; 121(6):1390-5. Camacho-Vanegas O, Narla G, Teixeira MS, DiFeo A, Misra A, Singh G, Chan AM, Friedman SL, Feuerstein BG, Martignetti JA. PMID: 17514651.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    18. Contribution of Notch signaling activation to human glioblastoma multiforme. J Neurosurg. 2007 Mar; 106(3):417-27. Kanamori M, Kawaguchi T, Nigro JM, Feuerstein BG, Berger MS, Miele L, Pieper RO. PMID: 17367064.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansCells
    19. Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma. Proc Natl Acad Sci U S A. 2007 Feb 27; 104(9):3466-71. Soroceanu L, Kharbanda S, Chen R, Soriano RH, Aldape K, Misra A, Zha J, Forrest WF, Nigro JM, Modrusan Z, Feuerstein BG, Phillips HS. PMID: 17360667; PMCID: PMC1802005.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    20. Genetic aberrations in gliomatosis cerebri. Neurosurgery. 2007 Jan; 60(1):150-8; discussion 158. Ware ML, Hirose Y, Scheithauer BW, Yeh RF, Mayo MC, Smith JS, Chang S, Cha S, Tihan T, Feuerstein BG. PMID: 17228264.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    21. Angiogenesis-independent tumor growth mediated by stem-like cancer cells. Proc Natl Acad Sci U S A. 2006 Oct 31; 103(44):16466-71. Sakariassen PØ, Prestegarden L, Wang J, Skaftnesmo KO, Mahesparan R, Molthoff C, Sminia P, Sundlisaeter E, Misra A, Tysnes BB, Chekenya M, Peters H, Lende G, Kalland KH, Øyan AM, Petersen K, Jonassen I, van der Kogel A, Feuerstein BG, Terzis AJ, Bjerkvig R, Enger PØ. PMID: 17056721; PMCID: PMC1618812.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansAnimalsCells
    22. A genetic strategy to overcome the senescence of primary meningioma cell cultures. J Neurooncol. 2006 Jun; 78(2):113-21. Baia GS, Slocum AL, Hyer JD, Misra A, Sehati N, VandenBerg SR, Feuerstein BG, Deen DF, McDermott MW, Lal A. PMID: 16554968.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    23. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell. 2006 Mar; 9(3):157-73. Phillips HS, Kharbanda S, Chen R, Forrest WF, Soriano RH, Wu TD, Misra A, Nigro JM, Colman H, Soroceanu L, Williams PM, Modrusan Z, Feuerstein BG, Aldape K. PMID: 16530701.
      View in: PubMed   Mentions: 1466     Fields:    Translation:Humans
    24. Chromosome transfer experiments link regions on chromosome 7 to radiation resistance in human glioblastoma multiforme. Genes Chromosomes Cancer. 2006 Jan; 45(1):20-30. Misra A, Pellarin M, Hu L, Kunwar S, Perhouse M, Lamborn KR, Deen DF, Feuerstein BG. PMID: 16130123.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    25. ZNF217 suppresses cell death associated with chemotherapy and telomere dysfunction. Hum Mol Genet. 2005 Nov 01; 14(21):3219-25. Huang G, Krig S, Kowbel D, Xu H, Hyun B, Volik S, Feuerstein B, Mills GB, Stokoe D, Yaswen P, Collins C. PMID: 16203743.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    26. Biphasic calcium response of platelet-derived growth factor stimulated glioblastoma cells is a function of cell confluence. Cytometry A. 2005 Oct; 67(2):172-9. Vereb G, Feuerstein BG, Hyun WC, Fulwyler MJ, Balázs M, Szöllosi J. PMID: 16163701.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    27. Isochromosome 17q is a negative prognostic factor in poor-risk childhood medulloblastoma patients. Clin Cancer Res. 2005 Jul 01; 11(13):4733-40. Pan E, Pellarin M, Holmes E, Smirnov I, Misra A, Eberhart CG, Burger PC, Biegel JA, Feuerstein BG. PMID: 16000568.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    28. Molecular cytogenetic analysis of chromosomes 1 and 19 in glioma cell lines. Cancer Genet Cytogenet. 2005 Jul 01; 160(1):1-14. Law ME, Templeton KL, Kitange G, Smith J, Misra A, Feuerstein BG, Jenkins RB. PMID: 15949564.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    29. Array comparative genomic hybridization identifies genetic subgroups in grade 4 human astrocytoma. Clin Cancer Res. 2005 Apr 15; 11(8):2907-18. Misra A, Pellarin M, Nigro J, Smirnov I, Moore D, Lamborn KR, Pinkel D, Albertson DG, Feuerstein BG. PMID: 15837741.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    30. Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma. Cancer Res. 2005 Mar 01; 65(5):1678-86. Nigro JM, Misra A, Zhang L, Smirnov I, Colman H, Griffin C, Ozburn N, Chen M, Pan E, Koul D, Yung WK, Feuerstein BG, Aldape KD. PMID: 15753362.
      View in: PubMed   Mentions: 115     Fields:    Translation:HumansCells
    31. Expression of the aquaporin-1 water channel in human glial tumors. Neurosurgery. 2005 Feb; 56(2):375-81; discussion 375-81. Oshio K, Binder DK, Liang Y, Bollen A, Feuerstein B, Berger MS, Manley GT. PMID: 15670385.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    32. Chromosomal imbalances detected by array comparative genomic hybridization in human oligodendrogliomas and mixed oligoastrocytomas. Genes Chromosomes Cancer. 2005 Jan; 42(1):68-77. Kitange G, Misra A, Law M, Passe S, Kollmeyer TM, Maurer M, Ballman K, Feuerstein BG, Jenkins RB. PMID: 15472895.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    33. A complex rearrangement of chromosome 7 in human astrocytoma. Cancer Genet Cytogenet. 2004 Jun; 151(2):162-70. Misra A, Pellarin M, Shapiro JR, Feuerstein BG. PMID: 15172755.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    34. Grade II astrocytomas are subgrouped by chromosome aberrations. Cancer Genet Cytogenet. 2003 Apr 01; 142(1):1-7. Hirose Y, Aldape KD, Chang S, Lamborn K, Berger MS, Feuerstein BG. PMID: 12660025.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    35. Genetic aberrations defined by comparative genomic hybridization distinguish long-term from typical survivors of glioblastoma. Cancer Res. 2002 Nov 01; 62(21):6205-10. Burton EC, Lamborn KR, Feuerstein BG, Prados M, Scott J, Forsyth P, Passe S, Jenkins RB, Aldape KD. PMID: 12414648.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    36. Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors. Nat Genet. 2002 Nov; 32(3):453-8. Zardo G, Tiirikainen MI, Hong C, Misra A, Feuerstein BG, Volik S, Collins CC, Lamborn KR, Bollen A, Pinkel D, Albertson DG, Costello JF. PMID: 12355068.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
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