Loading...

Burt Feuerstein, MD, PhD

TitleProfessor Emeritus
SchoolUCSF School of Medicine
DepartmentLaboratory Medicine
Address3333 California Street
San Francisco CA 94118
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency

    Collapse Overview 
    Collapse Overview
    Dr. Burt Feuerstein grew up in Buffalo, NY, and graduated from Wesleyan University with a BA in music (1972), and from the University at Buffalo School of Medicine and Dentistry/Roswell Park Cancer Institute with an MD and PhD in pharmacology (1979). He completed his pediatric residency and fellowship in pediatric hematology/oncology at the University of California San Francisco, and is presently emeritus professor of Lab Medicine and Neurological Surgery. Burt moved to Barrow Neurological Institute in 2006, and joined the University of Arizona College of Medicine – Phoenix in 2010. His academic interests are brain tumor diagnosis and therapy, and teaching project development in medicine.

    PATENT INFORMATION for Dr. Burt Feuerstein:

    Therapeutic polyamines
    Inventors: Basu; Hirak S. (Pacifica, CA), Feuerstein; Burt (San Francisco, CA), Marton; Laurence (Fitchburg, WI), Samejima; Keijiro (Kokubunji, Tokyo 185, JP)
    Family ID: 22521929
    Appl. No.: 08/147,527
    Filed: November 5, 1993

    Therapeutic polyamines
    Inventors: Feuerstein; Burt G. (San Francisco, CA), Mohapatra; Gayatry (San Francisco, CA), Kim; Dong H. (San Francisco, CA)
    Assignee: The Regents of the University of California (Oakland, CA)
    Family ID: 23595852
    Appl. No.: 08/403,457
    Filed: March 14, 1995

    Genetic gain and loss in gliomas
    Inventors: Feuerstein; Burt G. (San Francisco, CA), Mohapatra; Gayatry (San Francisco, CA), Kim; Dong H. (San Francisco, CA)
    Assignee: The Regents of the University of California (Oakland, CA)
    Family ID: 23595852
    Appl. No.: 08/403,457
    Filed: March 14, 1995

    Glioma-associated nucleic acid probes
    Inventors: Feuerstein; Burt G. (San Francisco, CA), Mohapatra; Gayatry (San Francisco, CA), Kim; Dong Hyung (San Francisco, CA)
    Assignee: The Regents of the University of California (Oakland, CA)
    Family ID: 23595852
    Appl. No.: 08/812,609
    Filed: March 6, 1997


    Collapse Research 
    Collapse Research Activities and Funding
    MOLECULAR CYTOGENETIC MARKERS IN GLIOMA PROGNOSIS
    NIH/NCI R01CA061147Aug 1, 1994 - Jun 30, 1998
    Role: Principal Investigator
    RATIONAL DEVELOPMENT OF POLYAMINE ANALOGUES
    NIH/NCI R29CA041757Dec 1, 1986 - Nov 30, 1991
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Martirosyan NL, Georges J, Kalani MY, Nakaji P, Spetzler RF, Feuerstein B, Preul MC. Handheld confocal laser endomicroscopic imaging utilizing tumor-specific fluorescent labeling to identify experimental glioma cells in vivo. Surg Neurol Int. 2016; 7(Suppl 40):S995-S1003. PMID: 28144472.
      View in: PubMed
    2. Singh G, Deutloff N, Maertens N, Meyer H, Awiszus F, Feuerstein B, Roessner A, Lohmann CH. Articulating polymethylmethacrylate (PMMA) spacers may have an immunomodulating effect on synovial tissue. Bone Joint J. 2016 Aug; 98-B(8):1062-8. PMID: 27482018.
      View in: PubMed
    3. Joy A, Kapoor M, Georges J, Butler L, Chang Y, Li C, Crouch A, Smirnov I, Nakada M, Hepler J, Marty M, Feuerstein B. The role of AKT isoforms in glioblastoma: AKT3 delays tumor progression. J Neurooncol. 2016 10; 130(1):43-52. PMID: 27422127.
      View in: PubMed
    4. Georges JF, Liu X, Eschbacher J, Nichols J, Mooney MA, Joy A, Spetzler RF, Feuerstein B, Preul MC, Anderson T, Yan H, Nakaji P. Use of a conformational switching aptamer for rapid and specific ex vivo identification of central nervous system lymphoma in a xenograft model. PLoS One. 2015; 10(4):e0123607. PMID: 25876071; PMCID: PMC4398547.
      View in: PubMed, PubMed Central
    5. Rodriguez FJ, Tihan T, Lin D, McDonald W, Nigro J, Feuerstein B, Jackson S, Cohen K, Burger PC. Clinicopathologic features of pediatric oligodendrogliomas: a series of 50 patients. Am J Surg Pathol. 2014 Aug; 38(8):1058-70. PMID: 24805856; PMCID: PMC4322928.
      View in: PubMed, PubMed Central
    6. Joy A, Ramesh A, Smirnov I, Reiser M, Misra A, Shapiro WR, Mills GB, Kim S, Feuerstein B. AKT pathway genes define 5 prognostic subgroups in glioblastoma. PLoS One. 2014; 9(7):e100827. PMID: 24984002; PMCID: PMC4077731.
      View in: PubMed, PubMed Central
    7. Georges JF, Martirosyan NL, Eschbacher J, Nichols J, Tissot M, Preul MC, Feuerstein B, Anderson T, Spetzler RF, Nakaji P. Sulforhodamine 101 selectively labels human astrocytoma cells in an animal model of glioblastoma. J Clin Neurosci. 2014 May; 21(5):846-51. PMID: 24666692.
      View in: PubMed
    8. Georges J, Zehri A, Carlson E, Nichols J, Mooney MA, Martirosyan NL, Ghaffari L, Kalani MY, Eschbacher J, Feuerstein B, Anderson T, Preul MC, Van Keuren-Jensen K, Nakaji P. Label-free microscopic assessment of glioblastoma biopsy specimens prior to biobanking [corrected]. Neurosurg Focus. 2014 Feb; 36(2):E8. PMID: 24484261.
      View in: PubMed
    9. Petrás M, Lajtos T, Friedländer E, Klekner A, Pintye E, Feuerstein B, Szöllosi J, Vereb G. Molecular interactions of ErbB1 (EGFR) and integrin-ß1 in astrocytoma frozen sections predict clinical outcome and correlate with Akt-mediated in vitro radioresistance. Neuro Oncol. 2013 Aug; 15(8):1027-40. PMID: 23595626; PMCID: PMC3714153.
      View in: PubMed, PubMed Central
    10. Behbahaninia M, Martirosyan NL, Georges J, Udovich JA, Kalani MY, Feuerstein B, Nakaji P, Spetzler RF, Preul MC. Intraoperative fluorescent imaging of intracranial tumors: a review. Clin Neurol Neurosurg. 2013 May; 115(5):517-28. PMID: 23523009.
      View in: PubMed
    11. von Bueren AO, Gerss J, Hagel C, Cai H, Remke M, Hasselblatt M, Feuerstein B, Pernet S, Delattre O, Korshunov A, Rutkowski S, Pfister SM, Baudis M. DNA copy number alterations in central primitive neuroectodermal tumors and tumors of the pineal region: an international individual patient data meta-analysis. J Neurooncol. 2012 Sep; 109(2):415-23. PMID: 22772606.
      View in: PubMed
    12. Hu LS, Eschbacher JM, Heiserman JE, Dueck AC, Shapiro WR, Liu S, Karis JP, Smith KA, Coons SW, Nakaji P, Spetzler RF, Feuerstein B, Debbins J, Baxter LC. Reevaluating the imaging definition of tumor progression: perfusion MRI quantifies recurrent glioblastoma tumor fraction, pseudoprogression, and radiation necrosis to predict survival. Neuro Oncol. 2012 Jul; 14(7):919-30. PMID: 22561797; PMCID: PMC3379799.
      View in: PubMed, PubMed Central
    13. Hu LS, Eschbacher JM, Dueck AC, Heiserman JE, Liu S, Karis JP, Smith KA, Shapiro WR, Pinnaduwage DS, Coons SW, Nakaji P, Debbins J, Feuerstein B, Baxter LC. Correlations between perfusion MR imaging cerebral blood volume, microvessel quantification, and clinical outcome using stereotactic analysis in recurrent high-grade glioma. AJNR Am J Neuroradiol. 2012 Jan; 33(1):69-76. PMID: 22095961.
      View in: PubMed
    14. Lambiv WL, Vassallo I, Delorenzi M, Shay T, Diserens AC, Misra A, Feuerstein B, Murat A, Migliavacca E, Hamou MF, Sciuscio D, Burger R, Domany E, Stupp R, Hegi ME. The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence. Neuro Oncol. 2011 Jul; 13(7):736-47. PMID: 21642372; PMCID: PMC3129269.
      View in: PubMed, PubMed Central
    15. Phillips JJ, Misra A, Feuerstein B, Kunwar S, Tihan T. Pituicytoma: characterization of a unique neoplasm by histology, immunohistochemistry, ultrastructure, and array-based comparative genomic hybridization. Arch Pathol Lab Med. 2010 Jul; 134(7):1063-9. PMID: 20586639; PMCID: PMC3161118.
      View in: PubMed, PubMed Central
    16. Colman H, Zhang L, Sulman EP, McDonald JM, Shooshtari NL, Rivera A, Popoff S, Nutt CL, Louis DN, Cairncross JG, Gilbert MR, Phillips HS, Mehta MP, Chakravarti A, Pelloski CE, Bhat K, Feuerstein B, Jenkins RB, Aldape K. A multigene predictor of outcome in glioblastoma. Neuro Oncol. 2010 Jan; 12(1):49-57. PMID: 20150367; PMCID: PMC2940562.
      View in: PubMed, PubMed Central
    17. Hu LS, Baxter LC, Pinnaduwage DS, Paine TL, Karis JP, Feuerstein B, Schmainda KM, Dueck AC, Debbins J, Smith KA, Nakaji P, Eschbacher JM, Coons SW, Heiserman JE. Optimized preload leakage-correction methods to improve the diagnostic accuracy of dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging in posttreatment gliomas. AJNR Am J Neuroradiol. 2010 Jan; 31(1):40-8. PMID: 19749223; PMCID: PMC4323177.
      View in: PubMed, PubMed Central
    18. Hu LS, Baxter LC, Smith KA, Feuerstein B, Karis JP, Eschbacher JM, Coons SW, Nakaji P, Yeh RF, Debbins J, Heiserman JE. Relative cerebral blood volume values to differentiate high-grade glioma recurrence from posttreatment radiation effect: direct correlation between image-guided tissue histopathology and localized dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging measurements. AJNR Am J Neuroradiol. 2009 Mar; 30(3):552-8. PMID: 19056837.
      View in: PubMed
    19. Prestegarden L, Misra A, Ware ML, Yeh RF, Bjerkvig R, Feuerstein B. Amplifying small amounts of tumor DNA allows detection of DNA copy number abberations with array-CGH. Biotechniques. 2008 Jun; 44(7):Piii-Pvi. PMID: 18533897.
      View in: PubMed
    20. Camacho-Vanegas O, Narla G, Teixeira MS, DiFeo A, Misra A, Singh G, Chan AM, Friedman SL, Feuerstein B, Martignetti JA. Functional inactivation of the KLF6 tumor suppressor gene by loss of heterozygosity and increased alternative splicing in glioblastoma. Int J Cancer. 2007 Sep 15; 121(6):1390-5. PMID: 17514651.
      View in: PubMed
    21. Tomioka N, Oba S, Ohira M, Misra A, Fridlyand J, Ishii S, Nakamura Y, Isogai E, Hirata T, Yoshida Y, Todo S, Kaneko Y, Albertson DG, Pinkel D, Feuerstein B, Nakagawara A. Novel risk stratification of patients with neuroblastoma by genomic signature, which is independent of molecular signature. Oncogene. 2008 Jan 17; 27(4):441-9. PMID: 17637744.
      View in: PubMed
    22. Kanamori M, Kawaguchi T, Nigro JM, Feuerstein B, Berger MS, Miele L, Pieper RO. Contribution of Notch signaling activation to human glioblastoma multiforme. J Neurosurg. 2007 Mar; 106(3):417-27. PMID: 17367064.
      View in: PubMed
    23. Soroceanu L, Kharbanda S, Chen R, Soriano RH, Aldape K, Misra A, Zha J, Forrest WF, Nigro JM, Modrusan Z, Feuerstein B, Phillips HS. Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma. Proc Natl Acad Sci U S A. 2007 Feb 27; 104(9):3466-71. PMID: 17360667; PMCID: PMC1802005.
      View in: PubMed, PubMed Central
    24. Ware ML, Hirose Y, Scheithauer BW, Yeh RF, Mayo MC, Smith JS, Chang S, Cha S, Tihan T, Feuerstein B. Genetic aberrations in gliomatosis cerebri. Neurosurgery. 2007 Jan; 60(1):150-8; discussion 158. PMID: 17228264.
      View in: PubMed
    25. Sakariassen PØ, Prestegarden L, Wang J, Skaftnesmo KO, Mahesparan R, Molthoff C, Sminia P, Sundlisaeter E, Misra A, Tysnes BB, Chekenya M, Peters H, Lende G, Kalland KH, Øyan AM, Petersen K, Jonassen I, van der Kogel A, Feuerstein B, Terzis AJ, Bjerkvig R, Enger PØ. Angiogenesis-independent tumor growth mediated by stem-like cancer cells. Proc Natl Acad Sci U S A. 2006 Oct 31; 103(44):16466-71. PMID: 17056721; PMCID: PMC1618812.
      View in: PubMed, PubMed Central
    26. Baia GS, Slocum AL, Hyer JD, Misra A, Sehati N, VandenBerg SR, Feuerstein B, Deen DF, McDermott MW, Lal A. A genetic strategy to overcome the senescence of primary meningioma cell cultures. J Neurooncol. 2006 Jun; 78(2):113-21. PMID: 16554968.
      View in: PubMed
    27. Phillips HS, Kharbanda S, Chen R, Forrest WF, Soriano RH, Wu TD, Misra A, Nigro JM, Colman H, Soroceanu L, Williams PM, Modrusan Z, Feuerstein B, Aldape K. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell. 2006 Mar; 9(3):157-73. PMID: 16530701.
      View in: PubMed
    28. Misra A, Pellarin M, Hu L, Kunwar S, Perhouse M, Lamborn KR, Deen DF, Feuerstein B. Chromosome transfer experiments link regions on chromosome 7 to radiation resistance in human glioblastoma multiforme. Genes Chromosomes Cancer. 2006 Jan; 45(1):20-30. PMID: 16130123.
      View in: PubMed
    29. Huang G, Krig S, Kowbel D, Xu H, Hyun B, Volik S, Feuerstein B, Mills GB, Stokoe D, Yaswen P, Collins C. ZNF217 suppresses cell death associated with chemotherapy and telomere dysfunction. Hum Mol Genet. 2005 Nov 01; 14(21):3219-25. PMID: 16203743.
      View in: PubMed
    30. Vereb G, Feuerstein B, Hyun WC, Fulwyler MJ, Balázs M, Szöllosi J. Biphasic calcium response of platelet-derived growth factor stimulated glioblastoma cells is a function of cell confluence. Cytometry A. 2005 Oct; 67(2):172-9. PMID: 16163701.
      View in: PubMed
    31. Pan E, Pellarin M, Holmes E, Smirnov I, Misra A, Eberhart CG, Burger PC, Biegel JA, Feuerstein B. Isochromosome 17q is a negative prognostic factor in poor-risk childhood medulloblastoma patients. Clin Cancer Res. 2005 Jul 01; 11(13):4733-40. PMID: 16000568.
      View in: PubMed
    32. Law ME, Templeton KL, Kitange G, Smith J, Misra A, Feuerstein B, Jenkins RB. Molecular cytogenetic analysis of chromosomes 1 and 19 in glioma cell lines. Cancer Genet Cytogenet. 2005 Jul 01; 160(1):1-14. PMID: 15949564.
      View in: PubMed
    33. Misra A, Pellarin M, Nigro J, Smirnov I, Moore D, Lamborn KR, Pinkel D, Albertson DG, Feuerstein B. Array comparative genomic hybridization identifies genetic subgroups in grade 4 human astrocytoma. Clin Cancer Res. 2005 Apr 15; 11(8):2907-18. PMID: 15837741.
      View in: PubMed
    34. Nigro JM, Misra A, Zhang L, Smirnov I, Colman H, Griffin C, Ozburn N, Chen M, Pan E, Koul D, Yung WK, Feuerstein B, Aldape KD. Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma. Cancer Res. 2005 Mar 01; 65(5):1678-86. PMID: 15753362.
      View in: PubMed
    35. Oshio K, Binder DK, Liang Y, Bollen A, Feuerstein B, Berger MS, Manley GT. Expression of the aquaporin-1 water channel in human glial tumors. Neurosurgery. 2005 Feb; 56(2):375-81; discussion 375-81. PMID: 15670385.
      View in: PubMed
    36. Kitange G, Misra A, Law M, Passe S, Kollmeyer TM, Maurer M, Ballman K, Feuerstein B, Jenkins RB. Chromosomal imbalances detected by array comparative genomic hybridization in human oligodendrogliomas and mixed oligoastrocytomas. Genes Chromosomes Cancer. 2005 Jan; 42(1):68-77. PMID: 15472895.
      View in: PubMed
    37. Misra A, Pellarin M, Shapiro JR, Feuerstein B. A complex rearrangement of chromosome 7 in human astrocytoma. Cancer Genet Cytogenet. 2004 Jun; 151(2):162-70. PMID: 15172755.
      View in: PubMed
    38. Hirose Y, Aldape KD, Chang S, Lamborn K, Berger MS, Feuerstein B. Grade II astrocytomas are subgrouped by chromosome aberrations. Cancer Genet Cytogenet. 2003 Apr 01; 142(1):1-7. PMID: 12660025.
      View in: PubMed
    39. Burton EC, Lamborn KR, Feuerstein B, Prados M, Scott J, Forsyth P, Passe S, Jenkins RB, Aldape KD. Genetic aberrations defined by comparative genomic hybridization distinguish long-term from typical survivors of glioblastoma. Cancer Res. 2002 Nov 01; 62(21):6205-10. PMID: 12414648.
      View in: PubMed
    40. Zardo G, Tiirikainen MI, Hong C, Misra A, Feuerstein B, Volik S, Collins CC, Lamborn KR, Bollen A, Pinkel D, Albertson DG, Costello JF. Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors. Nat Genet. 2002 Nov; 32(3):453-8. PMID: 12355068.
      View in: PubMed
    41. Kunwar S, Mohapatra G, Bollen A, Lamborn KR, Prados M, Feuerstein B. Genetic subgroups of anaplastic astrocytomas correlate with patient age and survival. Cancer Res. 2001 Oct 15; 61(20):7683-8. PMID: 11606412.
      View in: PubMed
    42. Burger PC, Minn AY, Smith JS, Borell TJ, Jedlicka AE, Huntley BK, Goldthwaite PT, Jenkins RB, Feuerstein B. Losses of chromosomal arms 1p and 19q in the diagnosis of oligodendroglioma. A study of paraffin-embedded sections. Mod Pathol. 2001 Sep; 14(9):842-53. PMID: 11557779.
      View in: PubMed
    43. Hirose Y, Aldape K, Takahashi M, Berger MS, Feuerstein B. Tissue microdissection and degenerate oligonucleotide primed-polymerase chain reaction (DOP-PCR) is an effective method to analyze genetic aberrations in invasive tumors. J Mol Diagn. 2001 May; 3(2):62-7. PMID: 11333301; PMCID: PMC1907353.
      View in: PubMed, PubMed Central
    44. Hirose Y, Aldape K, Bollen A, James CD, Brat D, Lamborn K, Berger M, Feuerstein B. Chromosomal abnormalities subdivide ependymal tumors into clinically relevant groups. Am J Pathol. 2001 Mar; 158(3):1137-43. PMID: 11238062; PMCID: PMC1850350.
      View in: PubMed, PubMed Central
    45. Plantaz D, Vandesompele J, Van Roy N, Lastowska M, Bown N, Combaret V, Favrot MC, Delattre O, Michon J, Bénard J, Hartmann O, Nicholson JC, Ross FM, Brinkschmidt C, Laureys G, Caron H, Matthay KK, Feuerstein B, Speleman F. Comparative genomic hybridization (CGH) analysis of stage 4 neuroblastoma reveals high frequency of 11q deletion in tumors lacking MYCN amplification. Int J Cancer. 2001 Mar 01; 91(5):680-6. PMID: 11267980.
      View in: PubMed
    46. Vandesompele J, Speleman F, Van Roy N, Laureys G, Brinskchmidt C, Christiansen H, Lampert F, Lastowska M, Bown N, Pearson A, Nicholson JC, Ross F, Combaret V, Delattre O, Feuerstein B, Plantaz D. Multicentre analysis of patterns of DNA gains and losses in 204 neuroblastoma tumors: how many genetic subgroups are there? Med Pediatr Oncol. 2001 Jan; 36(1):5-10. PMID: 11464905.
      View in: PubMed
    47. Glaser A, Schuler-Thurner B, Feuerstein B, Zingsem J, Zimmermann R, Weisbach V, Eckstein R. Collection of MNCs with two cell separators for adoptive immunotherapy in patients with stage IV melanoma. Transfusion. 2001 Jan; 41(1):117-22. PMID: 11161256.
      View in: PubMed
    48. Brat DJ, Hirose Y, Cohen KJ, Feuerstein B, Burger PC. Astroblastoma: clinicopathologic features and chromosomal abnormalities defined by comparative genomic hybridization. Brain Pathol. 2000 Jul; 10(3):342-52. PMID: 10885653.
      View in: PubMed
    49. Perry A, Anderl K, Borell TJ, Kimmel DW, Wang CH, O'Fallon JR, Feuerstein B, Scheithauer BW, Jenkins RB. Detection of p16, RB, CDK4, and p53 gene deletion and amplification by fluorescence in situ hybridization in 96 gliomas. Am J Clin Pathol. 1999 Dec; 112(6):801-9. PMID: 10587703.
      View in: PubMed
    50. Smith JS, Alderete B, Minn Y, Borell TJ, Perry A, Mohapatra G, Hosek SM, Kimmel D, O'Fallon J, Yates A, Feuerstein B, Burger PC, Scheithauer BW, Jenkins RB. Localization of common deletion regions on 1p and 19q in human gliomas and their association with histological subtype. Oncogene. 1999 Jul 15; 18(28):4144-52. PMID: 10435596.
      View in: PubMed
    51. Russo C, Pellarin M, Tingby O, Bollen AW, Lamborn KR, Mohapatra G, Collins VP, Feuerstein B. Comparative genomic hybridization in patients with supratentorial and infratentorial primitive neuroectodermal tumors. Cancer. 1999 Jul 15; 86(2):331-9. PMID: 10421270.
      View in: PubMed
    52. Huhn SL, Mohapatra G, Bollen A, Lamborn K, Prados MD, Feuerstein B. Chromosomal abnormalities in glioblastoma multiforme by comparative genomic hybridization: correlation with radiation treatment outcome. Clin Cancer Res. 1999 Jun; 5(6):1435-43. PMID: 10389929.
      View in: PubMed
    53. Metzger AK, Mohapatra G, Minn YA, Bollen AW, Lamborn K, Waldman FM, Wilson CB, Feuerstein B. Multiple genetic aberrations including evidence of chromosome 11q13 rearrangement detected in pituitary adenomas by comparative genomic hybridization. J Neurosurg. 1999 Feb; 90(2):306-14. PMID: 9950502.
      View in: PubMed
    54. Metzger AK, Minn YA, Lieberman D, Bollen AW, Wilson CB, Feuerstein B. CNS Resident Award. Malignant meningiomas frequently lose multiple chromosomal regions in addition to 22q: putative meningioma progression loci identified by comparative genomic hybridization. Clin Neurosurg. 1999; 45:6-7. PMID: 10461493.
      View in: PubMed
    55. Nagy P, Bene L, Balázs M, Hyun WC, Lockett SJ, Chiang NY, Waldman F, Feuerstein B, Damjanovich S, Szöllosi J. EGF-induced redistribution of erbB2 on breast tumor cells: flow and image cytometric energy transfer measurements. Cytometry. 1998 Jun 01; 32(2):120-31. PMID: 9627225.
      View in: PubMed
    56. Mohapatra G, Bollen AW, Kim DH, Lamborn K, Moore DH, Prados MD, Feuerstein B. Genetic analysis of glioblastoma multiforme provides evidence for subgroups within the grade. Genes Chromosomes Cancer. 1998 Mar; 21(3):195-206. PMID: 9523194.
      View in: PubMed
    57. Patel A, van Meyel DJ, Mohapatra G, Bollen A, Wrensch M, Cairncross JG, Feuerstein B. Gliomas in families: chromosomal analysis by comparative genomic hybridization. Cancer Genet Cytogenet. 1998 Jan 01; 100(1):77-83. PMID: 9406586.
      View in: PubMed
    58. Terzis AJ, Pedersen PH, Feuerstein B, Arnold H, Bjerkvig R, Deen DF. Effects of DFMO on glioma cell proliferation, migration and invasion in vitro. J Neurooncol. 1998 Jan; 36(2):113-21. PMID: 9525811.
      View in: PubMed
    59. Mohapatra G, Moore DH, Kim DH, Grewal L, Hyun WC, Waldman FM, Pinkel D, Feuerstein B. Analyses of brain tumor cell lines confirm a simple model of relationships among fluorescence in situ hybridization, DNA index, and comparative genomic hybridization. Genes Chromosomes Cancer. 1997 Dec; 20(4):311-9. PMID: 9408746.
      View in: PubMed
    60. McElhinney DB, Reddy VM, Feuerstein B, Marx GR, Hanley FL. Intraoperative discovery of neuroblastoma in an infant with pulmonary atresia. Ann Thorac Surg. 1997 Dec; 64(6):1827-9. PMID: 9436587.
      View in: PubMed
    61. Perry A, Nobori T, Ru N, Anderl K, Borell TJ, Mohapatra G, Feuerstein B, Jenkins RB, Carson DA. Detection of p16 gene deletions in gliomas: a comparison of fluorescence in situ hybridization (FISH) versus quantitative PCR. J Neuropathol Exp Neurol. 1997 Sep; 56(9):999-1008. PMID: 9291941.
      View in: PubMed
    62. Weiss WA, Aldape K, Mohapatra G, Feuerstein B, Bishop JM. Targeted expression of MYCN causes neuroblastoma in transgenic mice. EMBO J. 1997 Jun 02; 16(11):2985-95. PMID: 9214616; PMCID: PMC1169917.
      View in: PubMed, PubMed Central
    63. Zhen J, Feuerstein B, Vidair C, Hyun W, Young L, Kirsten E, Kun E. Cellular analysis of the mode of action of methyl-3,5-diiodo-4-(4'-methoxyphenoxy) benzoate (DIME) on tumor cells. Int J Oncol. 1997 May; 10(5):905-10. PMID: 21533461.
      View in: PubMed
    64. Liehr T, Park O, Feuerstein B, Gebhart E, Rautenstrauss B. The peripheral myelin protein 22 kDa (PMP22) gene is amplified in cell lines derived from glioma and osteogenic sarcoma. Int J Oncol. 1997 May; 10(5):915-9. PMID: 21533463.
      View in: PubMed
    65. Plantaz D, Mohapatra G, Matthay KK, Pellarin M, Seeger RC, Feuerstein B. Gain of chromosome 17 is the most frequent abnormality detected in neuroblastoma by comparative genomic hybridization. Am J Pathol. 1997 Jan; 150(1):81-9. PMID: 9006325; PMCID: PMC1858505.
      View in: PubMed, PubMed Central
    66. Vereb G, Szöllösi J, Mátyus L, Balázs M, Hyun WC, Feuerstein B. Depletion of intracellular calcium stores facilitates the influx of extracellular calcium in platelet derived growth factor stimulated A172 glioblastoma cells. Cytometry. 1996 May 01; 24(1):64-73. PMID: 8723904.
      View in: PubMed
    67. Sauter G, Maeda T, Waldman FM, Davis RL, Feuerstein B. Patterns of epidermal growth factor receptor amplification in malignant gliomas. Am J Pathol. 1996 Apr; 148(4):1047-53. PMID: 8644846; PMCID: PMC1861518.
      View in: PubMed, PubMed Central
    68. Basu HS, Pellarin M, Feuerstein B, Marton LJ. The ability of polyamine analogues to induce Z-DNA structure in synthetic polynucleotides in vitro inversely correlates with their effects on cytotoxicity of cis-diaminedichloroplatinum (II) (CDDP) in human brain tumor cell lines. Anticancer Res. 1996 Jan-Feb; 16(1):39-47. PMID: 8615642.
      View in: PubMed
    69. Clément S, Delcros JG, Feuerstein B. Spermine uptake is necessary to induce haemoglobin synthesis in murine erythroleukaemia cells. Biochem J. 1995 Dec 15; 312 ( Pt 3):933-8. PMID: 8554541; PMCID: PMC1136203.
      View in: PubMed, PubMed Central
    70. Szöllösi J, Balázs M, Feuerstein B, Benz CC, Waldman FM. ERBB-2 (HER2/neu) gene copy number, p185HER-2 overexpression, and intratumor heterogeneity in human breast cancer. Cancer Res. 1995 Nov 15; 55(22):5400-7. PMID: 7585609.
      View in: PubMed
    71. Schwartz B, Hittelman A, Daneshvar L, Basu HS, Marton LJ, Feuerstein B. A new model for disruption of the ornithine decarboxylase gene, SPE1, in Saccharomyces cerevisiae exhibits growth arrest and genetic instability at the MAT locus. Biochem J. 1995 Nov 15; 312 ( Pt 1):83-90. PMID: 7492339; PMCID: PMC1136230.
      View in: PubMed, PubMed Central
    72. Park SH, Maeda T, Mohapatra G, Waldman FM, Davis RL, Feuerstein B. Heterogeneity, polyploidy, aneusomy, and 9p deletion in human glioblastoma multiforme. Cancer Genet Cytogenet. 1995 Sep; 83(2):127-35. PMID: 7553582.
      View in: PubMed
    73. Delcros JG, Schwartz B, Clément S, Basu HS, Marton LJ, Feuerstein B. Spermine induces haemoglobin synthesis in murine erythroleukaemia cells. Biochem J. 1995 Aug 01; 309 ( Pt 3):781-6. PMID: 7639693; PMCID: PMC1135700.
      View in: PubMed, PubMed Central
    74. Clément S, Delcros JG, Basu HS, Quash G, Marton LJ, Feuerstein B. The structure of polyamine analogues determines haemoglobin production and cytotoxicity in murine erythroleukaemia cells. Biochem J. 1995 Aug 01; 309 ( Pt 3):787-91. PMID: 7639694; PMCID: PMC1135701.
      View in: PubMed, PubMed Central
    75. Mohapatra G, Kim DH, Feuerstein B. Detection of multiple gains and losses of genetic material in ten glioma cell lines by comparative genomic hybridization. Genes Chromosomes Cancer. 1995 Jun; 13(2):86-93. PMID: 7542911.
      View in: PubMed
    76. Kim DH, Mohapatra G, Bollen A, Waldman FM, Feuerstein B. Chromosomal abnormalities in glioblastoma multiforme tumors and glioma cell lines detected by comparative genomic hybridization. Int J Cancer. 1995 Mar 16; 60(6):812-9. PMID: 7896451.
      View in: PubMed
    77. Wang J, Basu HS, Hu L, Feuerstein B, Nederlof PM, Deen DF. Radiation-induced changes in nucleoid halo diameters of aerobic and hypoxic SF-126 human brain tumor cells. Cytometry. 1995 Feb 01; 19(2):107-11. PMID: 7743890.
      View in: PubMed
    78. Bergeron CJ, Basu HS, Marton LJ, Deen DF, Pellarin M, Feuerstein B. Two polyamine analogs (BE-4-4-4 and BE-4-4-4-4) directly affect growth, survival, and cell cycle progression in two human brain tumor cell lines. Cancer Chemother Pharmacol. 1995; 36(5):411-7. PMID: 7634383.
      View in: PubMed
    79. Feuerstein B, Mohapatra G. Molecular cytogenetic quantitation of gains and losses of genetic material from human gliomas. J Neurooncol. 1995; 24(1):47-55. PMID: 8523075.
      View in: PubMed
    80. Basu HS, Marton LJ, Pellarin M, Deen DF, McManis JS, Liu CZ, Bergeron RJ, Feuerstein B. Design and testing of novel cytotoxic polyamine analogues. Cancer Res. 1994 Dec 01; 54(23):6210-4. PMID: 7954468.
      View in: PubMed
    81. Smirnov IV, Feuerstein B, Pellarin M, Marton LJ, Deen DF, Basu HS. Pretreatment with the polyamine analog 1,19-bis-(ethylamino)-5,10,15-triazanonadecane (BE-4-4-4-4) inhibits etoposide cytotoxicity in U-251 MG (NCI) human brain tumor cells. Cell Mol Biol (Noisy-le-grand). 1994 Nov; 40(7):975-80. PMID: 7849564.
      View in: PubMed
    82. Dolan ME, Fleig MJ, Feuerstein B, Basu HS, Luk GD, Casero RA, Marton LJ. Effect of 1,19-bis(ethylamino)-5,10,15-triazanonadecane on human tumor xenografts. Cancer Res. 1994 Sep 01; 54(17):4698-702. PMID: 8062267.
      View in: PubMed
    83. Kristensson K, Feuerstein B, Taraboulos A, Hyun WC, Prusiner SB, DeArmond SJ. Scrapie prions alter receptor-mediated calcium responses in cultured cells. Neurology. 1993 Nov; 43(11):2335-41. PMID: 8232952.
      View in: PubMed
    84. Basu HS, Pellarin M, Feuerstein B, Deen DF, Marton LJ. Effects of the polyamine analogs BE-3-7-3, 3-8-3, and BE-3-8-3 on human brain tumor cell growth and survival. Anticancer Res. 1993 Sep-Oct; 13(5A):1525-32. PMID: 8239531.
      View in: PubMed
    85. Basu HS, Pellarin M, Feuerstein B, Shirahata A, Samejima K, Deen DF, Marton LJ. Interaction of a polyamine analogue, 1,19-bis-(ethylamino)-5,10,15- triazanonadecane (BE-4-4-4-4), with DNA and effect on growth, survival, and polyamine levels in seven human brain tumor cell lines. Cancer Res. 1993 Sep 01; 53(17):3948-55. PMID: 8358722.
      View in: PubMed
    86. Pershadsingh HA, Szollosi J, Benson S, Hyun WC, Feuerstein B, Kurtz TW. Effects of ciglitazone on blood pressure and intracellular calcium metabolism. Hypertension. 1993 Jun; 21(6 Pt 2):1020-3. PMID: 8505086.
      View in: PubMed
    87. Delcros JG, Sturkenboom MC, Basu HS, Shafer RH, Szöllösi J, Feuerstein B, Marton LJ. Differential effects of spermine and its analogues on the structures of polynucleotides complexed with ethidium bromide. Biochem J. 1993 Apr 01; 291 ( Pt 1):269-74. PMID: 8471043; PMCID: PMC1132512.
      View in: PubMed, PubMed Central
    88. Feuerstein B, Szöllösi J, Basu HS, Marton LJ. alpha-Difluoromethylornithine alters calcium signaling in platelet-derived growth factor-stimulated A172 brain tumor cells in culture. Cancer Res. 1992 Dec 15; 52(24):6782-9. PMID: 1458466.
      View in: PubMed
    89. Basu HS, Sturkenboom MC, Delcros JG, Csokan PP, Szollosi J, Feuerstein B, Marton LJ. Effect of polyamine depletion on chromatin structure in U-87 MG human brain tumour cells. Biochem J. 1992 Mar 15; 282 ( Pt 3):723-7. PMID: 1554353; PMCID: PMC1130847.
      View in: PubMed, PubMed Central
    90. Basu HS, Pellarin M, Feuerstein B, Deen DF, Marton LJ. Effect on N1,N14-bis-(ethyl)-homospermine (BE-4-4-4) on the growth of U-251 MG and SF-188 human brain tumor cells. Int J Cancer. 1991 Jul 30; 48(6):873-8. PMID: 1860734.
      View in: PubMed
    91. Szöllösi J, Feuerstein B, Vereb G, Pershadsingh HA, Marton LJ. Calcium channels in PDGF-stimulated A172 cells open after intracellular calcium release and are not voltage-dependent. Cell Calcium. 1991 Jul; 12(7):477-91. PMID: 1657394.
      View in: PubMed
    92. Balázs M, Szöllösi J, Lee WC, Haugland RP, Guzikowski AP, Fulwyler MJ, Damjanovich S, Feuerstein B, Pershadsingh HA. Fluorescent tetradecanoylphorbol acetate: a novel probe of phorbol ester binding domains. J Cell Biochem. 1991 Jul; 46(3):266-76. PMID: 1663503.
      View in: PubMed
    93. Banville DL, Feuerstein B, Shafer RH. 1H and 31P nuclear magnetic resonance studies of spermine binding to the Z-DNA form of d(m5CGm5CGm5CG)2. Evidence for decreased spermine mobility. J Mol Biol. 1991 Jun 20; 219(4):585-90. PMID: 1647463.
      View in: PubMed
    94. Feuerstein B, Williams LD, Basu HS, Marton LJ. Implications and concepts of polyamine-nucleic acid interactions. J Cell Biochem. 1991 May; 46(1):37-47. PMID: 1874798.
      View in: PubMed
    95. Szöllösi J, Feuerstein B, Hyun WC, Das MK, Marton LJ. Attachment of A172 human glioblastoma cells affects calcium signalling: a comparison of image cytometry, flow cytometry, and spectrofluorometry. Cytometry. 1991; 12(8):707-16. PMID: 1794252.
      View in: PubMed
    96. Basu HS, Schwietert HC, Feuerstein B, Marton LJ. Effects of variation in the structure of spermine on the association with DNA and the induction of DNA conformational changes. Biochem J. 1990 Jul 15; 269(2):329-34. PMID: 2386479; PMCID: PMC1131580.
      View in: PubMed, PubMed Central
    97. Basu HS, Pellarin M, Feuerstein B, Deen DF, Bergeron RJ, Marton LJ. Effect of N1,N14-bis(ethyl)homospermine on the growth of U-87 MG and SF-126 human brain tumor cells. Cancer Res. 1990 Jun 01; 50(11):3137-40. PMID: 2334909.
      View in: PubMed
    98. Feuerstein B, Pattabiraman N, Marton LJ. Molecular mechanics of the interactions of spermine with DNA: DNA bending as a result of ligand binding. Nucleic Acids Res. 1990 Mar 11; 18(5):1271-82. PMID: 2320418; PMCID: PMC330444.
      View in: PubMed, PubMed Central
    99. Zarling DA, Calhoun CJ, Feuerstein B, Sena EP. Cytoplasmic microinjection of immunoglobulin Gs recognizing RNA helices inhibits human cell growth. J Mol Biol. 1990 Jan 05; 211(1):147-60. PMID: 2153833.
      View in: PubMed
    100. Basu HS, Feuerstein B, Deen DF, Lubich WP, Bergeron RJ, Samejima K, Marton LJ. Correlation between the effects of polyamine analogues on DNA conformation and cell growth. Cancer Res. 1989 Oct 15; 49(20):5591-7. PMID: 2507131.
      View in: PubMed
    101. Feuerstein B, Pattabiraman N, Marton LJ. Molecular dynamics of spermine-DNA interactions: sequence specificity and DNA bending for a simple ligand. Nucleic Acids Res. 1989 Sep 12; 17(17):6883-92. PMID: 2780313; PMCID: PMC318419.
      View in: PubMed, PubMed Central
    102. Basu HS, Feuerstein B, Zarling DA, Shafer RH, Marton LJ. Recognition of Z-RNA and Z-DNA determinants by polyamines in solution: experimental and theoretical studies. J Biomol Struct Dyn. 1988 Oct; 6(2):299-309. PMID: 2482766.
      View in: PubMed
    103. Feuerstein B, Basu HS, Marton LJ. Theoretical and experimental characterization of polyamine/DNA interactions. Adv Exp Med Biol. 1988; 250:517-23. PMID: 2855561.
      View in: PubMed
    104. Mivechi NF, Dewey WC, Feuerstein B, Deen DF, Marton LJ. Relationship between heat sensitivity and polyamine levels after treatment with alpha-difluoromethylornithine (DFMO). Radiat Res. 1986 Dec; 108(3):269-81. PMID: 3099327.
      View in: PubMed
    105. Marton LJ, Feuerstein B. Polyamine-DNA Interactions: Possible Site of New Cancer Chemotherapeutic Intervention. Pharm Res. 1986 Dec; 3(6):311-7. PMID: 24271829.
      View in: PubMed
    106. Feuerstein B, Pattabiraman N, Marton LJ. Spermine-DNA interactions: a theoretical study. Proc Natl Acad Sci U S A. 1986 Aug; 83(16):5948-52. PMID: 3461466; PMCID: PMC386414.
      View in: PubMed, PubMed Central
    107. Feuerstein B, Pattabiraman N, Marton LJ. Theoretical models of spermine/DNA interactions. Ann N Y Acad Sci. 1986; 482:251-4. PMID: 3471109.
      View in: PubMed
    108. Feuerstein B, Deen DF, Marton LJ. Effects of dicyclohexylamine sulfate, a spermidine synthase inhibitor, in 9L rat brain tumor cells. Cancer Res. 1985 Oct; 45(10):4950-4. PMID: 3928144.
      View in: PubMed
    109. Feuerstein B, Marton LJ, Keniry MA, Wade DL, Shafer RH. New DNA polymorphism: evidence for a low salt, left-handed form of poly(dG-m5dC). Nucleic Acids Res. 1985 Jun 11; 13(11):4133-41. PMID: 4011444; PMCID: PMC341301.
      View in: PubMed, PubMed Central
    110. Oredsson SM, Tofilon PJ, Feuerstein B, Deen DF, Rosenblum ML, Marton LJ. Differential potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine in chloroethylnitrosourea-sensitive and -resistant 9L rat brain tumor cells in vitro. Cancer Res. 1983 Aug; 43(8):3576-8. PMID: 6407751.
      View in: PubMed
    111. Feuerstein B, Porter CW, Dave C. A selective effect of methylglyoxal-bis(guanylhydrazone) on the synthesis of mitochondrial DNA of cultured L1210 leukemia cells. Cancer Res. 1979 Oct; 39(10):4130-7. PMID: 476650.
      View in: PubMed
    112. Mikles-Robertson F, Feuerstein B, Dave C, Porter CW. The generality of methylglyoxal bis(guanylhydrazone)-induced mitochondrial damage and the dependence of this effect on cell proliferation. Cancer Res. 1979 Jun; 39(6 Pt 1):1919-26. PMID: 445392.
      View in: PubMed
    Burt's Networks
    Concepts
    Derived automatically from this person's publications.
    See all (472) concept(s)
    _
    Co-Authors
    People in Profiles who have published with this person.
    See all (18) people
    _
    Related Authors
    People who share related concepts with this person.
    See all (60) people
    _
    Back to TOP