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Burt Feuerstein, MD, PhD

Title(s)Professor Emeritus, Laboratory Medicine
SchoolSchool of Medicine
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency

    Collapse Overview 
    Collapse Overview
    Dr. Burt Feuerstein grew up in Buffalo, NY, and graduated from Wesleyan University with a BA in music (1972), and from the University at Buffalo School of Medicine and Dentistry/Roswell Park Cancer Institute with an MD and PhD in pharmacology (1979). He completed his pediatric residency and fellowship in pediatric hematology/oncology at the University of California San Francisco, and is presently emeritus professor of Lab Medicine and Neurological Surgery. Burt moved to Barrow Neurological Institute in 2006, and joined the University of Arizona College of Medicine – Phoenix in 2010. His academic interests are brain tumor diagnosis and therapy, and teaching project development in medicine.

    PATENT INFORMATION for Dr. Burt Feuerstein:

    Therapeutic polyamines
    Inventors: Basu; Hirak S. (Pacifica, CA), Feuerstein; Burt (San Francisco, CA), Marton; Laurence (Fitchburg, WI), Samejima; Keijiro (Kokubunji, Tokyo 185, JP)
    Family ID: 22521929
    Appl. No.: 08/147,527
    Filed: November 5, 1993

    Therapeutic polyamines
    Inventors: Feuerstein; Burt G. (San Francisco, CA), Mohapatra; Gayatry (San Francisco, CA), Kim; Dong H. (San Francisco, CA)
    Assignee: The Regents of the University of California (Oakland, CA)
    Family ID: 23595852
    Appl. No.: 08/403,457
    Filed: March 14, 1995

    Genetic gain and loss in gliomas
    Inventors: Feuerstein; Burt G. (San Francisco, CA), Mohapatra; Gayatry (San Francisco, CA), Kim; Dong H. (San Francisco, CA)
    Assignee: The Regents of the University of California (Oakland, CA)
    Family ID: 23595852
    Appl. No.: 08/403,457
    Filed: March 14, 1995

    Glioma-associated nucleic acid probes
    Inventors: Feuerstein; Burt G. (San Francisco, CA), Mohapatra; Gayatry (San Francisco, CA), Kim; Dong Hyung (San Francisco, CA)
    Assignee: The Regents of the University of California (Oakland, CA)
    Family ID: 23595852
    Appl. No.: 08/812,609
    Filed: March 6, 1997

    Collapse Research 
    Collapse Research Activities and Funding
    MOLECULAR CYTOGENETIC MARKERS IN GLIOMA PROGNOSIS
    NIH/NCI R01CA061147Aug 1, 1994 - Jun 30, 1998
    Role: Principal Investigator
    RATIONAL DEVELOPMENT OF POLYAMINE ANALOGUES
    NIH/NCI R29CA041757Dec 1, 1986 - Nov 30, 1991
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Martirosyan NL, Georges J, Kalani MY, Nakaji P, Spetzler RF, Feuerstein BG, Preul MC. Handheld confocal laser endomicroscopic imaging utilizing tumor-specific fluorescent labeling to identify experimental glioma cells in vivo. Surg Neurol Int. 2016; 7(Suppl 40):S995-S1003. PMID: 28144472.
      View in: PubMed
    2. Joy A, Kapoor M, Georges J, Butler L, Chang Y, Li C, Crouch A, Smirnov I, Nakada M, Hepler J, Marty M, Feuerstein BG. The role of AKT isoforms in glioblastoma: AKT3 delays tumor progression. J Neurooncol. 2016 10; 130(1):43-52. PMID: 27422127.
      View in: PubMed
    3. Georges JF, Liu X, Eschbacher J, Nichols J, Mooney MA, Joy A, Spetzler RF, Feuerstein BG, Preul MC, Anderson T, Yan H, Nakaji P. Use of a conformational switching aptamer for rapid and specific ex vivo identification of central nervous system lymphoma in a xenograft model. PLoS One. 2015; 10(4):e0123607. PMID: 25876071.
      View in: PubMed
    4. Rodriguez FJ, Tihan T, Lin D, McDonald W, Nigro J, Feuerstein B, Jackson S, Cohen K, Burger PC. Clinicopathologic features of pediatric oligodendrogliomas: a series of 50 patients. Am J Surg Pathol. 2014 Aug; 38(8):1058-70. PMID: 24805856.
      View in: PubMed
    5. Joy A, Ramesh A, Smirnov I, Reiser M, Misra A, Shapiro WR, Mills GB, Kim S, Feuerstein BG. AKT pathway genes define 5 prognostic subgroups in glioblastoma. PLoS One. 2014; 9(7):e100827. PMID: 24984002.
      View in: PubMed
    6. Georges JF, Martirosyan NL, Eschbacher J, Nichols J, Tissot M, Preul MC, Feuerstein B, Anderson T, Spetzler RF, Nakaji P. Sulforhodamine 101 selectively labels human astrocytoma cells in an animal model of glioblastoma. J Clin Neurosci. 2014 May; 21(5):846-51. PMID: 24666692.
      View in: PubMed
    7. Georges J, Zehri A, Carlson E, Nichols J, Mooney MA, Martirosyan NL, Ghaffari L, Kalani MY, Eschbacher J, Feuerstein B, Anderson T, Preul MC, Van Keuren-Jensen K, Nakaji P. Label-free microscopic assessment of glioblastoma biopsy specimens prior to biobanking [corrected]. Neurosurg Focus. 2014 Feb; 36(2):E8. PMID: 24484261.
      View in: PubMed
    8. Petrás M, Lajtos T, Friedländer E, Klekner A, Pintye E, Feuerstein BG, Szöllosi J, Vereb G. Molecular interactions of ErbB1 (EGFR) and integrin-ß1 in astrocytoma frozen sections predict clinical outcome and correlate with Akt-mediated in vitro radioresistance. Neuro Oncol. 2013 Aug; 15(8):1027-40. PMID: 23595626.
      View in: PubMed
    9. Behbahaninia M, Martirosyan NL, Georges J, Udovich JA, Kalani MY, Feuerstein BG, Nakaji P, Spetzler RF, Preul MC. Intraoperative fluorescent imaging of intracranial tumors: a review. Clin Neurol Neurosurg. 2013 May; 115(5):517-28. PMID: 23523009.
      View in: PubMed
    10. von Bueren AO, Gerss J, Hagel C, Cai H, Remke M, Hasselblatt M, Feuerstein BG, Pernet S, Delattre O, Korshunov A, Rutkowski S, Pfister SM, Baudis M. DNA copy number alterations in central primitive neuroectodermal tumors and tumors of the pineal region: an international individual patient data meta-analysis. J Neurooncol. 2012 Sep; 109(2):415-23. PMID: 22772606.
      View in: PubMed
    11. Hu LS, Eschbacher JM, Heiserman JE, Dueck AC, Shapiro WR, Liu S, Karis JP, Smith KA, Coons SW, Nakaji P, Spetzler RF, Feuerstein BG, Debbins J, Baxter LC. Reevaluating the imaging definition of tumor progression: perfusion MRI quantifies recurrent glioblastoma tumor fraction, pseudoprogression, and radiation necrosis to predict survival. Neuro Oncol. 2012 Jul; 14(7):919-30. PMID: 22561797.
      View in: PubMed
    12. Lambiv WL, Vassallo I, Delorenzi M, Shay T, Diserens AC, Misra A, Feuerstein B, Murat A, Migliavacca E, Hamou MF, Sciuscio D, Burger R, Domany E, Stupp R, Hegi ME. The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence. Neuro Oncol. 2011 Jul; 13(7):736-47. PMID: 21642372.
      View in: PubMed
    13. Phillips JJ, Misra A, Feuerstein BG, Kunwar S, Tihan T. Pituicytoma: characterization of a unique neoplasm by histology, immunohistochemistry, ultrastructure, and array-based comparative genomic hybridization. Arch Pathol Lab Med. 2010 Jul; 134(7):1063-9. PMID: 20586639.
      View in: PubMed
    14. Colman H, Zhang L, Sulman EP, McDonald JM, Shooshtari NL, Rivera A, Popoff S, Nutt CL, Louis DN, Cairncross JG, Gilbert MR, Phillips HS, Mehta MP, Chakravarti A, Pelloski CE, Bhat K, Feuerstein BG, Jenkins RB, Aldape K. A multigene predictor of outcome in glioblastoma. Neuro Oncol. 2010 Jan; 12(1):49-57. PMID: 20150367.
      View in: PubMed
    15. Prestegarden L, Misra A, Ware ML, Yeh RF, Bjerkvig R, Feuerstein BG. Amplifying small amounts of tumor DNA allows detection of DNA copy number abberations with array-CGH. Biotechniques. 2008 Jun; 44(7):Piii-Pvi. PMID: 18533897.
      View in: PubMed
    16. Camacho-Vanegas O, Narla G, Teixeira MS, DiFeo A, Misra A, Singh G, Chan AM, Friedman SL, Feuerstein BG, Martignetti JA. Functional inactivation of the KLF6 tumor suppressor gene by loss of heterozygosity and increased alternative splicing in glioblastoma. Int J Cancer. 2007 Sep 15; 121(6):1390-5. PMID: 17514651.
      View in: PubMed
    17. Kanamori M, Kawaguchi T, Nigro JM, Feuerstein BG, Berger MS, Miele L, Pieper RO. Contribution of Notch signaling activation to human glioblastoma multiforme. J Neurosurg. 2007 Mar; 106(3):417-27. PMID: 17367064.
      View in: PubMed
    18. Soroceanu L, Kharbanda S, Chen R, Soriano RH, Aldape K, Misra A, Zha J, Forrest WF, Nigro JM, Modrusan Z, Feuerstein BG, Phillips HS. Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma. Proc Natl Acad Sci U S A. 2007 Feb 27; 104(9):3466-71. PMID: 17360667.
      View in: PubMed
    19. Ware ML, Hirose Y, Scheithauer BW, Yeh RF, Mayo MC, Smith JS, Chang S, Cha S, Tihan T, Feuerstein BG. Genetic aberrations in gliomatosis cerebri. Neurosurgery. 2007 Jan; 60(1):150-8; discussion 158. PMID: 17228264.
      View in: PubMed
    20. Sakariassen PØ, Prestegarden L, Wang J, Skaftnesmo KO, Mahesparan R, Molthoff C, Sminia P, Sundlisaeter E, Misra A, Tysnes BB, Chekenya M, Peters H, Lende G, Kalland KH, Øyan AM, Petersen K, Jonassen I, van der Kogel A, Feuerstein BG, Terzis AJ, Bjerkvig R, Enger PØ. Angiogenesis-independent tumor growth mediated by stem-like cancer cells. Proc Natl Acad Sci U S A. 2006 Oct 31; 103(44):16466-71. PMID: 17056721.
      View in: PubMed
    21. Baia GS, Slocum AL, Hyer JD, Misra A, Sehati N, VandenBerg SR, Feuerstein BG, Deen DF, McDermott MW, Lal A. A genetic strategy to overcome the senescence of primary meningioma cell cultures. J Neurooncol. 2006 Jun; 78(2):113-21. PMID: 16554968.
      View in: PubMed
    22. Phillips HS, Kharbanda S, Chen R, Forrest WF, Soriano RH, Wu TD, Misra A, Nigro JM, Colman H, Soroceanu L, Williams PM, Modrusan Z, Feuerstein BG, Aldape K. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell. 2006 Mar; 9(3):157-73. PMID: 16530701.
      View in: PubMed
    23. Misra A, Pellarin M, Hu L, Kunwar S, Perhouse M, Lamborn KR, Deen DF, Feuerstein BG. Chromosome transfer experiments link regions on chromosome 7 to radiation resistance in human glioblastoma multiforme. Genes Chromosomes Cancer. 2006 Jan; 45(1):20-30. PMID: 16130123.
      View in: PubMed
    24. Huang G, Krig S, Kowbel D, Xu H, Hyun B, Volik S, Feuerstein B, Mills GB, Stokoe D, Yaswen P, Collins C. ZNF217 suppresses cell death associated with chemotherapy and telomere dysfunction. Hum Mol Genet. 2005 Nov 01; 14(21):3219-25. PMID: 16203743.
      View in: PubMed
    25. Vereb G, Feuerstein BG, Hyun WC, Fulwyler MJ, Balázs M, Szöllosi J. Biphasic calcium response of platelet-derived growth factor stimulated glioblastoma cells is a function of cell confluence. Cytometry A. 2005 Oct; 67(2):172-9. PMID: 16163701.
      View in: PubMed
    26. Pan E, Pellarin M, Holmes E, Smirnov I, Misra A, Eberhart CG, Burger PC, Biegel JA, Feuerstein BG. Isochromosome 17q is a negative prognostic factor in poor-risk childhood medulloblastoma patients. Clin Cancer Res. 2005 Jul 01; 11(13):4733-40. PMID: 16000568.
      View in: PubMed
    27. Law ME, Templeton KL, Kitange G, Smith J, Misra A, Feuerstein BG, Jenkins RB. Molecular cytogenetic analysis of chromosomes 1 and 19 in glioma cell lines. Cancer Genet Cytogenet. 2005 Jul 01; 160(1):1-14. PMID: 15949564.
      View in: PubMed
    28. Misra A, Pellarin M, Nigro J, Smirnov I, Moore D, Lamborn KR, Pinkel D, Albertson DG, Feuerstein BG. Array comparative genomic hybridization identifies genetic subgroups in grade 4 human astrocytoma. Clin Cancer Res. 2005 Apr 15; 11(8):2907-18. PMID: 15837741.
      View in: PubMed
    29. Nigro JM, Misra A, Zhang L, Smirnov I, Colman H, Griffin C, Ozburn N, Chen M, Pan E, Koul D, Yung WK, Feuerstein BG, Aldape KD. Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma. Cancer Res. 2005 Mar 01; 65(5):1678-86. PMID: 15753362.
      View in: PubMed
    30. Oshio K, Binder DK, Liang Y, Bollen A, Feuerstein B, Berger MS, Manley GT. Expression of the aquaporin-1 water channel in human glial tumors. Neurosurgery. 2005 Feb; 56(2):375-81; discussion 375-81. PMID: 15670385.
      View in: PubMed
    31. Kitange G, Misra A, Law M, Passe S, Kollmeyer TM, Maurer M, Ballman K, Feuerstein BG, Jenkins RB. Chromosomal imbalances detected by array comparative genomic hybridization in human oligodendrogliomas and mixed oligoastrocytomas. Genes Chromosomes Cancer. 2005 Jan; 42(1):68-77. PMID: 15472895.
      View in: PubMed
    32. Misra A, Pellarin M, Shapiro JR, Feuerstein BG. A complex rearrangement of chromosome 7 in human astrocytoma. Cancer Genet Cytogenet. 2004 Jun; 151(2):162-70. PMID: 15172755.
      View in: PubMed
    33. Hirose Y, Aldape KD, Chang S, Lamborn K, Berger MS, Feuerstein BG. Grade II astrocytomas are subgrouped by chromosome aberrations. Cancer Genet Cytogenet. 2003 Apr 01; 142(1):1-7. PMID: 12660025.
      View in: PubMed
    34. Burton EC, Lamborn KR, Feuerstein BG, Prados M, Scott J, Forsyth P, Passe S, Jenkins RB, Aldape KD. Genetic aberrations defined by comparative genomic hybridization distinguish long-term from typical survivors of glioblastoma. Cancer Res. 2002 Nov 01; 62(21):6205-10. PMID: 12414648.
      View in: PubMed
    35. Zardo G, Tiirikainen MI, Hong C, Misra A, Feuerstein BG, Volik S, Collins CC, Lamborn KR, Bollen A, Pinkel D, Albertson DG, Costello JF. Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors. Nat Genet. 2002 Nov; 32(3):453-8. PMID: 12355068.
      View in: PubMed
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