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Functional characterization of Alzheimer's disease genetic variants in microglia. Nat Genet. 2023 Oct; 55(10):1735-1744.
Yang X, Wen J, Yang H, Jones IR, Zhu X, Liu W, Li B, Clelland CD, Luo W, Wong MY, Ren X, Cui X, Song M, Liu H, Chen C, Eng N, Ravichandran M, Sun Y, Lee D, Van Buren E, Jiang MZ, Chan CSY, Ye CJ, Perera RM, Gan L, Li Y, Shen Y. PMID: 37735198.
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HumansCells
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Emerging roles of the MiT/TFE factors in cancer. Trends Cancer. 2023 10; 9(10):817-827.
Zoncu R, Perera RM. PMID: 37400313.
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HumansCells
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Coordinated Transcriptional and Catabolic Programs Support Iron-Dependent Adaptation to RAS-MAPK Pathway Inhibition in Pancreatic Cancer. Cancer Discov. 2022 09 02; 12(9):2198-2219.
Ravichandran M, Hu J, Cai C, Ward NP, Venida A, Foakes C, Kuljanin M, Yang A, Hennessey CJ, Yang Y, Desousa BR, Rademaker G, Staes AAL, Cakir Z, Jain IH, Aguirre AJ, Mancias JD, Shen Y, DeNicola GM, Perera RM. PMID: 35771494; PMCID: PMC9444964.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1. Science. 2022 09 16; 377(6612):1290-1298.
Shin HR, Citron YR, Wang L, Tribouillard L, Goul CS, Stipp R, Sugasawa Y, Jain A, Samson N, Lim CY, Davis OB, Castaneda-Carpio D, Qian M, Nomura DK, Perera RM, Park E, Covey DF, Laplante M, Evers AS, Zoncu R. PMID: 36007018; PMCID: PMC10023259.
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13 Fields:
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HumansCells
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Autophagy in cancer cell remodeling and quality control. Mol Cell. 2022 04 21; 82(8):1514-1527.
Hernandez GA, Perera RM. PMID: 35452618; PMCID: PMC9119670.
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11 Fields:
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HumansCells
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Built to last: lysosome remodeling and repair in health and disease. Trends Cell Biol. 2022 07; 32(7):597-610.
Zoncu R, Perera RM. PMID: 35123838; PMCID: PMC9189017.
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8 Fields:
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HumansCells
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Challenges and opportunities in 2021. Nat Cancer. 2021 12; 2(12):1278-1283.
Akkari L, Finley SD, Ho PC, Jenkins M, Maier BB, McGranahan N, Mutebi M, Perera RM, Robles-Espinoza CD, Vardhana S, Wan L, Xu MM. PMID: 35121916.
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Zooming in on the cell biology of disease. Mol Biol Cell. 2021 12 01; 32(22):ae4.
Perera RM. PMID: 34747628; PMCID: PMC8694084.
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HumansAnimalsCells
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Autophagy in major human diseases. EMBO J. 2021 10 01; 40(19):e108863.
Klionsky DJ, Petroni G, Amaravadi RK, Baehrecke EH, Ballabio A, Boya P, Bravo-San Pedro JM, Cadwell K, Cecconi F, Choi AMK, Choi ME, Chu CT, Codogno P, Colombo MI, Cuervo AM, Deretic V, Dikic I, Elazar Z, Eskelinen EL, Fimia GM, Gewirtz DA, Green DR, Hansen M, Jäättelä M, Johansen T, Juhász G, Karantza V, Kraft C, Kroemer G, Ktistakis NT, Kumar S, Lopez-Otin C, Macleod KF, Madeo F, Martinez J, Meléndez A, Mizushima N, Münz C, Penninger JM, Perera RM, Piacentini M, Reggiori F, Rubinsztein DC, Ryan KM, Sadoshima J, Santambrogio L, Scorrano L, Simon HU, Simon AK, Simonsen A, Stolz A, Tavernarakis N, Tooze SA, Yoshimori T, Yuan J, Yue Z, Zhong Q, Galluzzi L, Pietrocola F. PMID: 34459017; PMCID: PMC8488577.
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PubMed Mentions:
277 Fields:
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HumansAnimalsCells
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Oncogene-regulated release of extracellular vesicles. Dev Cell. 2021 07 12; 56(13):1989-2006.e6.
Kilinc S, Paisner R, Camarda R, Gupta S, Momcilovic O, Kohnz RA, Avsaroglu B, L'Etoile ND, Perera RM, Nomura DK, Goga A. PMID: 34118203; PMCID: PMC8292920.
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18 Fields:
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HumansCells
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Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth. Nat Cell Biol. 2021 03; 23(3):232-242.
Gupta S, Yano J, Mercier V, Htwe HH, Shin HR, Rademaker G, Cakir Z, Ituarte T, Wen KW, Kim GE, Zoncu R, Roux A, Dawson DW, Perera RM. PMID: 33686253; PMCID: PMC9446896.
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23 Fields:
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HumansAnimalsCells
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Lysosomes and Cancer. Innovation in Aging. 2020 Dec 16; 4(Suppl 1):744-744.
Perera PR. .
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NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C. Dev Cell. 2021 02 08; 56(3):260-276.e7.
Davis OB, Shin HR, Lim CY, Wu EY, Kukurugya M, Maher CF, Perera RM, Ordonez MP, Zoncu R. PMID: 33308480; PMCID: PMC8919971.
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PubMed Mentions:
48 Fields:
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HumansAnimalsCells
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Selective autophagy of MHC-I promotes immune evasion of pancreatic cancer. Autophagy. 2020 08; 16(8):1524-1525.
Yamamoto K, Venida A, Perera RM, Kimmelman AC. PMID: 32459143; PMCID: PMC7469632.
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29 Fields:
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HumansAnimalsCells
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Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I. Nature. 2020 05; 581(7806):100-105.
Yamamoto K, Venida A, Yano J, Biancur DE, Kakiuchi M, Gupta S, Sohn ASW, Mukhopadhyay S, Lin EY, Parker SJ, Banh RS, Paulo JA, Wen KW, Debnath J, Kim GE, Mancias JD, Fearon DT, Perera RM, Kimmelman AC. PMID: 32376951; PMCID: PMC7296553.
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356 Fields:
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HumansAnimalsCells
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Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer. Elife. 2019 05 28; 8.
Adams CR, Htwe HH, Marsh T, Wang AL, Montoya ML, Subbaraj L, Tward AD, Bardeesy N, Perera RM. PMID: 31134896; PMCID: PMC6538376.
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40 Fields:
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HumansAnimalsCells
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Host Control of Tumor Feeding: Autophagy Holds the Key. Cell Metab. 2019 02 05; 29(2):236-238.
Venida A, Perera RM. PMID: 30726755.
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4 Fields:
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Humans
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Burnout among emergency physicians working at a large tertiary centre in Ontario. Journal of Wellness. 2019 Jan 1; 1(1):1-4.
Perera PR. .
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MiT/TFE Family of Transcription Factors, Lysosomes, and Cancer. Annu Rev Cancer Biol. 2019 03; 3:203-222.
Perera RM, Di Malta C, Ballabio A. PMID: 31650096; PMCID: PMC6812561.
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54
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Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth. Science. 2017 06 16; 356(6343):1188-1192.
Di Malta C, Siciliano D, Calcagni A, Monfregola J, Punzi S, Pastore N, Eastes AN, Davis O, De Cegli R, Zampelli A, Di Giovannantonio LG, Nusco E, Platt N, Guida A, Ogmundsdottir MH, Lanfrancone L, Perera RM, Zoncu R, Pelicci PG, Settembre C, Ballabio A. PMID: 28619945; PMCID: PMC5730647.
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114 Fields:
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HumansAnimalsCells
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Lysosomal cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex. Science. 2017 03 24; 355(6331):1306-1311.
Castellano BM, Thelen AM, Moldavski O, Feltes M, van der Welle RE, Mydock-McGrane L, Jiang X, van Eijkeren RJ, Davis OB, Louie SM, Perera RM, Covey DF, Nomura DK, Ory DS, Zoncu R. PMID: 28336668; PMCID: PMC5823611.
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PubMed Mentions:
233 Fields:
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HumansAnimalsCells
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Beige Adipocyte Maintenance Is Regulated by Autophagy-Induced Mitochondrial Clearance. Cell Metab. 2016 09 13; 24(3):402-419.
Altshuler-Keylin S, Shinoda K, Hasegawa Y, Ikeda K, Hong H, Kang Q, Yang Y, Perera RM, Debnath J, Kajimura S. PMID: 27568548; PMCID: PMC5023491.
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PubMed Mentions:
164 Fields:
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AnimalsCells
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The Lysosome as a Regulatory Hub. Annu Rev Cell Dev Biol. 2016 10 06; 32:223-253.
Perera RM, Zoncu R. PMID: 27501449; PMCID: PMC9345128.
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228 Fields:
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HumansAnimalsCells
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Pancreatic Cancer Metabolism: Breaking It Down to Build It Back Up. Cancer Discov. 2015 Dec; 5(12):1247-61.
Perera RM, Bardeesy N. PMID: 26534901; PMCID: PMC4687899.
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90 Fields:
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HumansAnimalsCells
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Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Nature. 2015 Aug 20; 524(7565):361-5.
Perera RM, Stoykova S, Nicolay BN, Ross KN, Fitamant J, Boukhali M, Lengrand J, Deshpande V, Selig MK, Ferrone CR, Settleman J, Stephanopoulos G, Dyson NJ, Zoncu R, Ramaswamy S, Haas W, Bardeesy N. PMID: 26168401; PMCID: PMC5086585.
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PubMed Mentions:
419 Fields:
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HumansAnimalsCells
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YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression. Cell Rep. 2015 Mar 17; 10(10):1692-1707.
Fitamant J, Kottakis F, Benhamouche S, Tian HS, Chuvin N, Parachoniak CA, Nagle JM, Perera RM, Lapouge M, Deshpande V, Zhu AX, Lai A, Min B, Hoshida Y, Avruch J, Sia D, Campreciós G, McClatchey AI, Llovet JM, Morrissey D, Raj L, Bardeesy N. PMID: 25772357; PMCID: PMC4565791.
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125 Fields:
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Stromal response to Hedgehog signaling restrains pancreatic cancer progression. Proc Natl Acad Sci U S A. 2014 Jul 29; 111(30):E3091-100.
Lee JJ, Perera RM, Wang H, Wu DC, Liu XS, Han S, Fitamant J, Jones PD, Ghanta KS, Kawano S, Nagle JM, Deshpande V, Boucher Y, Kato T, Chen JK, Willmann JK, Bardeesy N, Beachy PA. PMID: 25024225; PMCID: PMC4121834.
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274 Fields:
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HumansAnimalsCells
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CDK4/6 and IGF1 receptor inhibitors synergize to suppress the growth of p16INK4A-deficient pancreatic cancers. Cancer Res. 2014 Jul 15; 74(14):3947-58.
Heilmann AM, Perera RM, Ecker V, Nicolay BN, Bardeesy N, Benes CH, Dyson NJ. PMID: 24986516; PMCID: PMC4122288.
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66 Fields:
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HumansAnimalsCells
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Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. Nature. 2013 Apr 04; 496(7443):101-5.
Son J, Lyssiotis CA, Ying H, Wang X, Hua S, Ligorio M, Perera RM, Ferrone CR, Mullarky E, Shyh-Chang N, Kang Y, Fleming JB, Bardeesy N, Asara JM, Haigis MC, DePinho RA, Cantley LC, Kimmelman AC. PMID: 23535601; PMCID: PMC3656466.
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PubMed Mentions:
966 Fields:
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HumansCells
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Ready, set, go: the EGF receptor at the pancreatic cancer starting line. Cancer Cell. 2012 Sep 11; 22(3):281-2.
Perera RM, Bardeesy N. PMID: 22975369; PMCID: PMC3564545.
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15 Fields:
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On oncogenes and tumor suppressor genes in the mammary gland. Cold Spring Harb Perspect Biol. 2012 Jun 01; 4(6).
Perera RM, Bardeesy N. PMID: 22661637; PMCID: PMC3367547.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Cancer: when antioxidants are bad. Nature. 2011 Jul 06; 475(7354):43-4.
Perera RM, Bardeesy N. PMID: 21734699.
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31 Fields:
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HumansAnimalsCells
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The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics. J Cell Biol. 2010 Aug 09; 190(3):307-15.
Nakatsu F, Perera RM, Lucast L, Zoncu R, Domin J, Gertler FB, Toomre D, De Camilli P. PMID: 20679431; PMCID: PMC2922640.
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PubMed Mentions:
58 Fields:
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AnimalsCells
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Canadian Surgery Forum. Can J Surg. 2010 Aug; 53(4):S51-S104.
Atlas H, Safa N, Denis R, Garneau P, Moustarah F, Marceau S, Lebel S, Biertho L, Hould F, Marceau P, Biron S, Anvari M, Sharma A, Goldsmith CH, Lacobellis G, Cadeddu M, Misra M, Taylor V, Tarride J, Hubert E, Tiboni M, Hong D, Wiebe S, Klassen D, Bonjer J, Lawlor D, Plowman J, Ransom T, Vallis M, Ellsmere J, Graham PJ, Kaban GK, Vizhul A, Birch DW, Menezes AC, Shi X, Karmali S, Seth R, MacKenzie L, Kus A, Bell J, Carrier M, Atkins H, Boushey R, Auer R, Croome KP, Yamashita M, Aarts MA, Okrainec A, Glicksman A, Pearsall E, Pitzul K, Huang H, McLeod RS, Sarkhosh K, Robertson M, Boctor D, Lam V, Sigalet D, Johner A, Faulds J, Wiseman SM, Pemberton J, Gordon ML, Prashad C, Rambaran M, Cameron B, Neville A, Sarosi GA, Wei Y, Gibbs JO, Reda DJ, McCarthy M, Fitzgibbons RJ, Barkun JST, Fenech DS, Forbes S, Pearsall E, Chung J, Glickman A, Victor JC, Nathens A, McLeod RS, Fitzmaurice GJ, Mone F, Brown R, Cranley B, Conlon EF, Todd RAJ, O'Donnell ME, Tran TT, Kaneva PA, Finch LE, Fried GM, Mayo NE, Feldman LS, VanHouwellingen L, Vogt KN, Stewart TC, Williamson J, Parry N, DeRose G, Gray D, Harriman S, Rodych N, Hayes P, Moser M, Jamal MH, Doi S, Rousseau M, Snell L, Meterissian S, Zolfaghari S, Friedlich MS, Kurashima Y, Al-Sabah S, Kaneva PA, Feldman LS, Fried GM, Vassiliou MC, Tran TT, Kaneva PA, Mayo NE, Fried GM, Feldman LS, Pearsall E, Sheth U, Fenech D, McKenzie M, Victor JC, McLeod RS, Ghaderi I, Vaillancourt M, Sroka G, Kaneva PA, Vassiliou MC, Seagull FJ, Sutton E, Godinez C, George I, Park A, Choy I, Okrainec A, Brintzenhoff R, Prabhu A, Heniford BT, Stefanidis D, Fried GM, Feldman LS, Igric A, Vogt KN, Girotti M, Parry NG, Vinden C, Kim SHH, Zhang NN, Russo JJ, El-Salfiti IK, Kowalczuk M, Rajaee AN, Bal M, Gill MS, Lysecki PJ, Hoogenes J, Dath D, Nassar AK, Reid S, Mohaisen KN, Winch J, Omar D, Hanna WC, Mulder DS, El-Hilali MM, Khwaja KA, Jamal MH, Rayment J, Doi SA, Megueditchian A, Meterissian S, Tso D, Langer M, Blair G, Butterworth S, Vaillancourt M, Vassiliou MC, Bergman S, Fried GM, Kaneva PA, Feldman LS, Davenport E, Haggar F, Trottier D, Huynh H, Soto C, Shamji FM, Seely A, Sundaresan S, Pagliarello G, Tadros S, Yelle JD, Maziak D, Moloo H, Poulin EC, Mamazza J, Knowlton LM, Chackungal S, MacQueen KA, Anvari M, Allen C, Goldsmith C, ELVIS Research Group, Ghaderi I, Madani A, de Gara C, Schlachta CM, Zakrison TL, Tee MC, Chan S, Nguyen V, Yang J, Holmes D, Levine D, Bugis S, Wiseman SM, Sandhu L, Zhai J, Kennedy ED, Baxter NN, Gagliardi AR, Urbach DR, Wei AC, Sabalbal M, McAlister VC, Balayla J, Bergman S, Feldman LS, Ghitulescu G, Fraser SA, Daigle R, Urquart R, Cox M, Grunfeld E, Porter G, Hallet J, Labidi S, Clairoux A, Gagné JP, Gill RS, Manouchehri N, Liu JQ, Lee TF, Bigam DL, Cheung PY, Van Koughnett JA, Colquhoun PH, Gordon ML, Cornacchi S, Farrokhyar F, Hodgson N, Porter G, Quan ML, Wright F, Lovrics P, Datta I, Brar SS, Ball CG, Heine JA, Rothwell B, Crozier M, Ting H, Boone D, O'Regan N, Brown C, Bandrauk N, Hapgood J, Hogan M, McDonald LA, Da'as S, Sorensen PHB, Berman JN, Ameer A, Jamal M, Aljiffry M, Doi S, Hasanain M, Chaudhury P, Metrakos P, Tchervenkov J, Lapierre S, Mohammad W, Balaa N, Akil M, Mimeault R, Fairfull-Smith R, Teague BD, Butler MS, Garneau PY, Sample CB, Kapoor A, Cadeddu MO, Anvari M, Hanna WC, Jamal MH, Nguyen L, Fraser SA, Kwan K, Wallis CJD, Jones S, Fraser T, Masterso J, Blair G, Duffy D, Roberts DJ, Kirkpatrick AW, Datta I, Feliciano DV, Kortbeek JB, Laupland KB, Ball CG, Haggar F, Davenport E, Moloo H, Mamazza J, Manouchehri N, Bigam D, Churchill T, Joynt C, Cheung PY, Al-Sairafi R, Sample CB, Paquette F, Fraser SA, Feldman LS, Fried GM, Weissglas I, Ghitulescu G, Meterissian S, Bergman S, Al-Dohayan A, Al-Naami M, Bamehriz F, Madkhali A, Hallet J, LeBlanc M, Gilbert A, Daigle C, Tien G, Atkins MS, Zheng B, Tanin H, Swindells C, Meneghetti A, Panton ONM, Qayumi AK, Chhiv M, Drolet S, Sirois-Giguère É, Gilbert A, Doyle JD, Sheth U, Huang H, Pearsall E, McLeod RS, et al. PMID: 35488396; PMCID: PMC2912011.
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Abstract 1346: Neutrophils facilitate metastasis by increasing cancer cell recruitment to liver sinusoids. Tumor Biology. 2010 Apr 15; 1346-1346.
Spicer SJ, Perera PR, MacDonald MB, Rousseau RM, Chan CC, Hsu HR, Giannias GB, Ferri FL. .
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Abstract 3434: Lipopoylsaccharide promotes human esophageal cancer cell metastatic potential via the selectin/sialyl Lewis X axis. Tumor Biology. 2010 Apr 15; 3434-3434.
Rousseau RM, Hsu HR, Spicer SJ, McDonald MB, Chan CC, Perera PR, Giannias GB, Ferri FL. .
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Abstract 5279: LPS-TLR4 binding increases metastatic potential of colorectal cancer cells. Tumor Biology. 2010 Apr 15; 5279-5279.
Hsu HR, Chan CC, Spicer SJ, Rousseau RM, Perera PR, Giannias GB, Rousseau RS, Ferri FL. .
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A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers. Cancer Res. 2010 Mar 15; 70(6):2158-64.
Rothenberg SM, Mohapatra G, Rivera MN, Winokur D, Greninger P, Nitta M, Sadow PM, Sooriyakumar G, Brannigan BW, Ulman MJ, Perera RM, Wang R, Tam A, Ma XJ, Erlander M, Sgroi DC, Rocco JW, Lingen MW, Cohen EE, Louis DN, Settleman J, Haber DA. PMID: 20215515; PMCID: PMC2881662.
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PubMed Mentions:
44 Fields:
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HumansCells
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Mechanistic Insights into Membrane Remodeling Through BAR-Domain Proteins. The FASEB Journal. 2009 Apr 1; 23:82.2-82.2.
Frost FA, Mim MC, Perera PR, Spasov SK, Egelman EE, De Camilli DP, Unger UV. .
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A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes. Cell. 2009 Mar 20; 136(6):1110-21.
Zoncu R, Perera RM, Balkin DM, Pirruccello M, Toomre D, De Camilli P. PMID: 19303853; PMCID: PMC2705806.
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PubMed Mentions:
186 Fields:
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AnimalsCells
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Structural basis of membrane invagination by F-BAR domains. Cell. 2008 Mar 07; 132(5):807-17.
Frost A, Perera R, Roux A, Spasov K, Destaing O, Egelman EH, De Camilli P, Unger VM. PMID: 18329367; PMCID: PMC2384079.
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PubMed Mentions:
293 Fields:
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HumansAnimalsCells
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Internalization, intracellular trafficking, and biodistribution of monoclonal antibody 806: a novel anti-epidermal growth factor receptor antibody. Neoplasia. 2007 Dec; 9(12):1099-110.
Perera RM, Zoncu R, Johns TG, Pypaert M, Lee FT, Mellman I, Old LJ, Toomre DK, Scott AM. PMID: 18084617; PMCID: PMC2134906.
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PubMed Mentions:
33 Fields:
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HumansAnimalsCells
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Reactive Oxygen Species Formation by UV-A Irradiation of Urocanic Acid and the Role of Trace Metals in This Chemistry¶. Photochemistry and Photobiology. 2007 May 1; 78(6):567-575.
Menon ME, Perera PR, Kuhn KR, Morrison MH. .
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Photobiological Properties of Positively Charged Methylene Violet Analogs. Photochemistry and Photobiology. 2007 May 1; 71(1):20-28.
Houghtaling HM, Perera PR, Owen OK, Wagner WS, Kuhn KR, Morrison MH. .
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The efficacy of epidermal growth factor receptor-specific antibodies against glioma xenografts is influenced by receptor levels, activation status, and heterodimerization. Clin Cancer Res. 2007 Mar 15; 13(6):1911-25.
Johns TG, Perera RM, Vernes SC, Vitali AA, Cao DX, Cavenee WK, Scott AM, Furnari FB. PMID: 17363548.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate. Proc Natl Acad Sci U S A. 2007 Mar 06; 104(10):3793-8.
Zoncu R, Perera RM, Sebastian R, Nakatsu F, Chen H, Balla T, Ayala G, Toomre D, De Camilli PV. PMID: 17360432; PMCID: PMC1805489.
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PubMed Mentions:
145 Fields:
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HumansAnimalsCells
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Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages. Proc Natl Acad Sci U S A. 2006 Dec 19; 103(51):19332-7.
Perera RM, Zoncu R, Lucast L, De Camilli P, Toomre D. PMID: 17158794; PMCID: PMC1693868.
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PubMed Mentions:
90 Fields:
Translation:
AnimalsCells
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Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor-specific antibody generates enhanced antitumor activity. Clin Cancer Res. 2005 Sep 01; 11(17):6390-9.
Perera RM, Narita Y, Furnari FB, Gan HK, Murone C, Ahlkvist M, Luwor RB, Burgess AW, Stockert E, Jungbluth AA, Old LJ, Cavenee WK, Scott AM, Johns TG. PMID: 16144944.
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31 Fields:
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HumansAnimalsCells
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The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR. Oncogene. 2004 Aug 12; 23(36):6095-104.
Luwor RB, Zhu HJ, Walker F, Vitali AA, Perera RM, Burgess AW, Scott AM, Johns TG. PMID: 15221011.
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44 Fields:
Translation:
AnimalsCells
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Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478. Proc Natl Acad Sci U S A. 2003 Dec 23; 100(26):15871-6.
Johns TG, Luwor RB, Murone C, Walker F, Weinstock J, Vitali AA, Perera RM, Jungbluth AA, Stockert E, Old LJ, Nice EC, Burgess AW, Scott AM. PMID: 14676326; PMCID: PMC307660.
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PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells