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Rushika Perera, PhD

Photo of Rushika Perera, PhD
Title(s)Professor, Anatomy
SchoolSchool of Medicine
Address513 Parnassus Avenue HSW
San Francisco CA 94143
PronounsShe/Her/Hers
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    Other Positions
    Title(s)Deborah Cowan Endowed Professor


    Collapse Overview 
    Collapse overview
    In our lab we study how autophagy and the lysosome regulate the response to cellular stress to promote cancer progression.

    Collapse Biography 
    Collapse awards and honors
    American Association for Cancer Research2023  - 2025AACR Transformative Cancer Research Award
    American Society for Cell Biology2021Gunter Blobel Early Career Award recipient
    Damon Runyon Cancer Reserach Foundation2016  - 2020Damon Runyon-Rachleff Innovation Award
    National Institute of Health2016  - 2021Director's New Innovator Award
    AACR-Pancreatic Cancer Action Network2016  - 2018Career Development Award
    American Association for Cancer Research2015NEXTGen Star

    Collapse Research 
    Collapse Featured Publications
    Collapse research activities and funding
    2026 Autophagy in Stress, Development and Disease Gordon Research Conference and Gordon Research Seminar
    NIH R13CA310706Mar 10, 2026 - Feb 28, 2027
    Role: Principal Investigator
    Identifying and disabling new pathways for macromolecular recycling in pancreatic cancer
    NIH R01CA301386Apr 1, 2025 - Mar 31, 2030
    Role: Principal Investigator
    Targeting the autophagy-lysosome system to block pancreatic cancer
    NIH R01CA251726Apr 1, 2021 - Mar 31, 2026
    Role: Principal Investigator
    Dissecting new mechanisms of lysosome quality control in health and disease
    NIH R01CA260249Apr 1, 2021 - Mar 31, 2026
    Role: Principal Investigator
    Identifying Molecular Drivers of Cellular Plasticity in Pancreatic Cancer
    NIH R01CA240603Sep 3, 2020 - May 31, 2025
    Role: Principal Investigator
    Tracking tumor evolution through in vivo organelle profiling
    NIH DP2CA216364Sep 30, 2016 - May 31, 2021
    Role: Principal Investigator

    Collapse Featured Content 

    Collapse Bibliographic 
    Collapse publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Treatment-Related Adverse Events and Health-Related Quality of Life Associated With Immune Checkpoint Inhibitor Treatment for Mucosal Head and Neck Squamous Cell Carcinoma: A Scoping Review. Head Neck. 2026 Jun 01. O'Donnell ND, Ward EC, Wishart LR, Perera R, Barrett C, Edmiston KA, Mitchell E, Pigott A, Pitt R, Russell K, Chan BA, Ladwa R. PMID: 42226019.
      View in: PubMed   Mentions:    Fields:    
    2. A multi-subunit autophagic capture complex facilitates degradation of ER-stalled MHC class I in pancreatic cancer. Mol Cell. 2026 May 29. Berquez M, Li AL, Luy MA, Venida AC, McDowall S, O'Loughlin T, Rademaker G, Barpanda A, Hu J, Yano J, Wiita AP, Gilbert LA, Bruno PM, Perera RM. PMID: 42214332.
      View in: PubMed   Mentions:    Fields:    
    3. Deep learning and radiomics models in patients with advanced non-small cell lung cancer treated with immunotherapy combined with stereotactic radiotherapy. Sci Rep. 2026 May 28. Kothari G, Hardcastle N, Perera R, Jackson P, Lee S, Silver JD, Gaudreault M, Li J, Brown C, Mitchell PLR, Kron T, Welsh JW, Theelen WSME, Siva S. PMID: 42174085.
      View in: PubMed   Mentions:    Fields:    
    4. Erratum to "Links between COVID-19, long COVID, and neurodegeneration: The role of glycosphingolipids" [Pharmacological Reviews 78 (2026) 100113]. Pharmacol Rev. 2026 May 20; 78(4):100142. Spedding M, Aerts J, Alexander S, Bellozzi Woestelandt AG, Chiricozzi E, Henriques A, Lledo PM, Loeffler JP, Perera R, Platt FM, Pradat PF, Rene F, Schapira A, St Clair L, Talbot K, Taquet M, Toborek M, Turner B, Zandi M, Gressens P. PMID: 42160940.
      View in: PubMed   Mentions:    Fields:    
    5. 25th Annual Meeting of the Rocky Mountain Virology Association. Viruses. 2026 Apr 14; 18(4). Byrne-Haber TJ, Pham KN, Joob A, Pinto SM, Ratnayake OC, Thompson R, Rovnak J, Perera R. PMID: 42043253; PMCID: PMC13120276.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. Links between COVID-19, long COVID, and neurodegeneration: The role of glycosphingolipids. Pharmacol Rev. 2026 Mar; 78(2):100113. Spedding M, Aerts J, Alexander S, Bellozzi Woestelandt AG, Chiricozzi E, Henriques A, Lledo PM, Loeffler JP, Perera R, Platt FM, Pradat PF, Rene F, Schapira A, St Clair L, Talbot K, Taquet M, Toborek M, Turner B, Zandi M, Gressens P. PMID: 41740316.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCellsPHPublic Health
    7. Perturbed pediatric circulating metabolome in mild and severe dengue disease. J Virol. 2025 11 25; 99(11):e0157225. Soma PS, Gullberg RC, Graham B, Islam MN, Kuan G, Balmaseda A, Blair CD, Beaty BJ, Belisle JT, Harris E, Perera R. PMID: 41159750; PMCID: PMC12645983.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. PCSK9 drives sterol-dependent metastatic organ choice in pancreatic cancer. Nature. 2025 07; 643(8074):1381-1390. Rademaker G, Hernandez GA, Seo Y, Dahal S, Miller-Phillips L, Li AL, Peng XL, Luan C, Qiu L, Liegeois MA, Wang B, Wen KW, Kim GE, Collisson EA, Kruger SF, Boeck S, Ormanns S, Guenther M, Heinemann V, Haas M, Looney MR, Yeh JJ, Zoncu R, Perera RM. PMID: 40399683; PMCID: PMC13064930.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    9. Hypoxia Induces Extensive Protein and Proteolytic Remodeling of the Cell Surface in Pancreatic Adenocarcinoma (PDAC) Cell Lines. J Proteome Res. 2025 Jun 06; 24(6):2791-2800. Lui I, Schaefer K, Kirkemo LL, Zhou J, Perera RM, Leung KK, Wells JA. PMID: 40312771; PMCID: PMC12161487.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    10. Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins. Science. 2025 03 28; 387(6741):eadq8331. Jain A, Heremans I, Rademaker G, Detomasi TC, Rohweder P, Anderson D, Zhang J, Hernandez GA, Gupta S, von Linde T, Lange M, Spacci M, Luo J, Citron YR, Olzmann JA, Dawson DW, Craik CS, Bommer G, Perera RM, Zoncu R. PMID: 40146846; PMCID: PMC12832182.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    11. The 24th Annual Meeting of the Rocky Mountain Virology Association. Viruses. 2025 02 14; 17(2). Dirks KR, Pinto SM, Pham KN, Byrne-Haber TJ, Thompson RW, Ratnayake OC, Rovnak J, Perera R. PMID: 40007017; PMCID: PMC11861888.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    12. Functional screen identifies RBM42 as a mediator of oncogenic mRNA translation specificity. Nat Cell Biol. 2025 Mar; 27(3):518-529. Kovalski JR, Sarioglu G, Subramanyam V, Hernandez G, Rademaker G, Oses-Prieto JA, Slota M, Mohan N, Yiakis K, Liu I, Wen KW, Kim GE, Miglani S, Burlingame AL, Goodarzi H, Perera RM, Ruggero D. PMID: 39905246; PMCID: PMC12758615.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    13. Leucine Aminopeptidase LyLAP enables lysosomal degradation of membrane proteins. bioRxiv. 2024 Dec 14. Jain A, Heremans I, Rademaker G, Detomasi TC, Hernandez GA, Zhang J, Gupta S, von Linde T, Lange M, Spacci M, Rohweder P, Anderson D, Citron YR, Olzmann JA, Dawson DW, Craik CS, Bommer G, Perera RM, Zoncu R. PMID: 39713462; PMCID: PMC11661280.
      View in: PubMed   Mentions:
    14. A multi-subunit autophagic capture complex facilitates degradation of ER stalled MHC-I in pancreatic cancer. bioRxiv. 2024 Oct 29. Berquez M, Li AL, Luy MA, Venida AC, O'Loughlin T, Rademaker G, Barpanda A, Hu J, Yano J, Wiita A, Gilbert LA, Bruno PM, Perera RM. PMID: 39554122; PMCID: PMC11565957.
      View in: PubMed   Mentions: 1  
    15. Functional screen for mediators of onco-mRNA translation specificity. bioRxiv. 2024 Oct 11. Kovalski JR, Sarioglu G, Subramanyam V, Hernandez G, Rademaker G, Oses-Prieto JA, Slota M, Mohan N, Yiakis K, Liu I, Wen KW, Kim GE, Miglani S, Burlingame AL, Goodarzi H, Perera RM, Ruggero D. PMID: 39416102; PMCID: PMC11482963.
      View in: PubMed   Mentions:
    16. Ocular TB in Western Australia. Int J Tuberc Lung Dis. 2024 Jul 01; 28(7):322-327. Suo M, Kenworthy MK, Richards J, Tay-Kearney ML, Farah H, Perera R. PMID: 38961550.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. The 23rd Annual Meeting of the Rocky Mountain Virology Association. Viruses. 2024 04 10; 16(4). Brehm AL, Dunham TJ, Pinto SM, Williams KA, Coffin KL, Ring ME, Ratnayake OC, Rovnak J, Perera R. PMID: 38675927; PMCID: PMC11053980.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    18. Lysosomes as coordinators of cellular catabolism, metabolic signalling and organ physiology. Nat Rev Mol Cell Biol. 2024 Mar; 25(3):223-245. Settembre C, Perera RM. PMID: 38001393.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCells
    19. Human mRNA in saliva can correctly identify individuals harboring acute infection. mBio. 2023 12 19; 14(6):e0171223. Yang Q, Meyerson NR, Paige CL, Morrison JH, Clark SK, Fattor WT, Decker CJ, Steiner HR, Lian E, Larremore DB, Perera R, Poeschla EM, Parker R, Dowell RD, Sawyer SL. PMID: 37943059; PMCID: PMC10746177.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Functional characterization of Alzheimer's disease genetic variants in microglia. Nat Genet. 2023 10; 55(10):1735-1744. Yang X, Wen J, Yang H, Jones IR, Zhu X, Liu W, Li B, Clelland CD, Luo W, Wong MY, Ren X, Cui X, Song M, Liu H, Chen C, Eng N, Ravichandran M, Sun Y, Lee D, Van Buren E, Jiang MZ, Chan CSY, Ye CJ, Perera RM, Gan L, Li Y, Shen Y. PMID: 37735198; PMCID: PMC10939305.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    21. Emerging roles of the MiT/TFE factors in cancer. Trends Cancer. 2023 10; 9(10):817-827. Zoncu R, Perera RM. PMID: 37400313.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    22. Recent Reports on Bioactive Compounds from Marine Cyanobacteria in Relation to Human Health Applications. Life (Basel). 2023 Jun 19; 13(6). Perera RMTD, Herath KHINM, Sanjeewa KKA, Jayawardena TU. PMID: 37374193; PMCID: PMC10301180.
      View in: PubMed   Mentions: 15  
    23. Coordinated Transcriptional and Catabolic Programs Support Iron-Dependent Adaptation to RAS-MAPK Pathway Inhibition in Pancreatic Cancer. Cancer Discov. 2022 09 02; 12(9):2198-2219. Ravichandran M, Hu J, Cai C, Ward NP, Venida A, Foakes C, Kuljanin M, Yang A, Hennessey CJ, Yang Y, Desousa BR, Rademaker G, Staes AAL, Cakir Z, Jain IH, Aguirre AJ, Mancias JD, Shen Y, DeNicola GM, Perera RM. PMID: 35771494; PMCID: PMC9444964.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    24. Electrochemical Capillary Driven Immunoassay for Detection of SARS-CoV-2. ACS Meas Sci Au. 2022 Dec 21; 2(6):584-594. Clark KM, Schenkel MS, Pittman TW, Samper IC, Anderson LBR, Khamcharoen W, Elmegerhi S, Perera R, Siangproh W, Kennan AJ, Geiss BJ, Dandy DS, Henry CS. PMID: 36570470; PMCID: PMC9469961.
      View in: PubMed   Mentions: 10  
    25. Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1. Science. 2022 09 16; 377(6612):1290-1298. Shin HR, Citron YR, Wang L, Tribouillard L, Goul CS, Stipp R, Sugasawa Y, Jain A, Samson N, Lim CY, Davis OB, Castaneda-Carpio D, Qian M, Nomura DK, Perera RM, Park E, Covey DF, Laplante M, Evers AS, Zoncu R. PMID: 36007018; PMCID: PMC10023259.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    26. Nicotine has no significant cytoprotective activity against SARS-CoV-2 infection. PLoS One. 2022; 17(8):e0272941. Zheng F, Lian E, Ramirez G, McAlister C, Zhou S, Zhang W, Liu C, Perera R, Zhan CG. PMID: 35980910; PMCID: PMC9387791.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    27. Autophagy in cancer cell remodeling and quality control. Mol Cell. 2022 04 21; 82(8):1514-1527. Hernandez GA, Perera RM. PMID: 35452618; PMCID: PMC9119670.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    28. Cross-tissue and generation predictability of relative Wolbachia densities in the mosquito Aedes aegypti. Parasit Vectors. 2022 Apr 12; 15(1):128. Mejia AJ, Dutra HLC, Jones MJ, Perera R, McGraw EA. PMID: 35413938; PMCID: PMC9004076.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    29. Built to last: lysosome remodeling and repair in health and disease. Trends Cell Biol. 2022 07; 32(7):597-610. Zoncu R, Perera RM. PMID: 35123838; PMCID: PMC9189017.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    30. Acyl-Coa Thioesterases: A Rheostat That Controls Activated Fatty Acids Modulates Dengue Virus Serotype 2 Replication. Viruses. 2022 01 25; 14(2). St Clair LA, Mills SA, Lian E, Soma PS, Nag A, Montgomery C, Ramirez G, Chotiwan N, Gullberg RC, Perera R. PMID: 35215835; PMCID: PMC8875275.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    31. Zooming in on the cell biology of disease. Mol Biol Cell. 2021 12 01; 32(22):ae4. Perera RM. PMID: 34747628; PMCID: PMC8694084.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    32. Challenges and opportunities in 2021. Nat Cancer. 2021 12; 2(12):1278-1283. Akkari L, Finley SD, Ho PC, Jenkins M, Maier BB, McGranahan N, Mutebi M, Perera RM, Robles-Espinoza CD, Vardhana S, Wan L, Xu MM. PMID: 35121916.
      View in: PubMed   Mentions:    Fields:    
    33. Autophagy in major human diseases. EMBO J. 2021 10 01; 40(19):e108863. Klionsky DJ, Petroni G, Amaravadi RK, Baehrecke EH, Ballabio A, Boya P, Bravo-San Pedro JM, Cadwell K, Cecconi F, Choi AMK, Choi ME, Chu CT, Codogno P, Colombo MI, Cuervo AM, Deretic V, Dikic I, Elazar Z, Eskelinen EL, Fimia GM, Gewirtz DA, Green DR, Hansen M, Jäättelä M, Johansen T, Juhász G, Karantza V, Kraft C, Kroemer G, Ktistakis NT, Kumar S, Lopez-Otin C, Macleod KF, Madeo F, Martinez J, Meléndez A, Mizushima N, Münz C, Penninger JM, Perera RM, Piacentini M, Reggiori F, Rubinsztein DC, Ryan KM, Sadoshima J, Santambrogio L, Scorrano L, Simon HU, Simon AK, Simonsen A, Stolz A, Tavernarakis N, Tooze SA, Yoshimori T, Yuan J, Yue Z, Zhong Q, Galluzzi L, Pietrocola F. PMID: 34459017; PMCID: PMC8488577.
      View in: PubMed   Mentions: 828     Fields:    Translation:HumansAnimalsCells
    34. Characterization of subclinical ZIKV infection in immune-competent guinea pigs and mice. J Gen Virol. 2021 08; 102(8). Westrich JA, McNulty EE, Edmonds MJ, Nalls AV, Miller MR, Foy BD, Rovnak J, Perera R, Mathiason CK. PMID: 34410903; PMCID: PMC8513637.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    35. Oncogene-regulated release of extracellular vesicles. Dev Cell. 2021 07 12; 56(13):1989-2006.e6. Kilinc S, Paisner R, Camarda R, Gupta S, Momcilovic O, Kohnz RA, Avsaroglu B, L'Etoile ND, Perera RM, Nomura DK, Goga A. PMID: 34118203; PMCID: PMC8292920.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    36. Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth. Nat Cell Biol. 2021 03; 23(3):232-242. Gupta S, Yano J, Mercier V, Htwe HH, Shin HR, Rademaker G, Cakir Z, Ituarte T, Wen KW, Kim GE, Zoncu R, Roux A, Dawson DW, Perera RM. PMID: 33686253; PMCID: PMC9446896.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    37. NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C. Dev Cell. 2021 02 08; 56(3):260-276.e7. Davis OB, Shin HR, Lim CY, Wu EY, Kukurugya M, Maher CF, Perera RM, Ordonez MP, Zoncu R. PMID: 33308480; PMCID: PMC8919971.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansAnimalsCells
    38. Dengue virus dominates lipid metabolism modulations in Wolbachia-coinfected Aedes aegypti. Commun Biol. 2020 09 18; 3(1):518. Koh C, Islam MN, Ye YH, Chotiwan N, Graham B, Belisle JT, Kouremenos KA, Dayalan S, Tull DL, Klatt S, Perera R, McGraw EA. PMID: 32948809; PMCID: PMC7501868.
      View in: PubMed   Mentions: 36  Translation:HumansAnimalsCellsPHPublic Health
    39. Selective autophagy of MHC-I promotes immune evasion of pancreatic cancer. Autophagy. 2020 08; 16(8):1524-1525. Yamamoto K, Venida A, Perera RM, Kimmelman AC. PMID: 32459143; PMCID: PMC7469632.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    40. Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I. Nature. 2020 05; 581(7806):100-105. Yamamoto K, Venida A, Yano J, Biancur DE, Kakiuchi M, Gupta S, Sohn ASW, Mukhopadhyay S, Lin EY, Parker SJ, Banh RS, Paulo JA, Wen KW, Debnath J, Kim GE, Mancias JD, Fearon DT, Perera RM, Kimmelman AC. PMID: 32376951; PMCID: PMC7296553.
      View in: PubMed   Mentions: 698     Fields:    Translation:HumansAnimalsCells
    41. Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer. Elife. 2019 05 28; 8. Adams CR, Htwe HH, Marsh T, Wang AL, Montoya ML, Subbaraj L, Tward AD, Bardeesy N, Perera RM. PMID: 31134896; PMCID: PMC6538376.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    42. Host Control of Tumor Feeding: Autophagy Holds the Key. Cell Metab. 2019 02 05; 29(2):236-238. Venida A, Perera RM. PMID: 30726755.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    43. MiT/TFE Family of Transcription Factors, Lysosomes, and Cancer. Annu Rev Cancer Biol. 2019 03; 3:203-222. Perera RM, Di Malta C, Ballabio A. PMID: 31650096; PMCID: PMC6812561.
      View in: PubMed   Mentions: 86  
    44. Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth. Science. 2017 06 16; 356(6343):1188-1192. Di Malta C, Siciliano D, Calcagni A, Monfregola J, Punzi S, Pastore N, Eastes AN, Davis O, De Cegli R, Zampelli A, Di Giovannantonio LG, Nusco E, Platt N, Guida A, Ogmundsdottir MH, Lanfrancone L, Perera RM, Zoncu R, Pelicci PG, Settembre C, Ballabio A. PMID: 28619945; PMCID: PMC5730647.
      View in: PubMed   Mentions: 149     Fields:    Translation:HumansAnimalsCells
    45. Rapid and specific detection of Asian- and African-lineage Zika viruses. Sci Transl Med. 2017 05 03; 9(388). Chotiwan N, Brewster CD, Magalhaes T, Weger-Lucarelli J, Duggal NK, Rückert C, Nguyen C, Garcia Luna SM, Fauver JR, Andre B, Gray M, Black WC, Kading RC, Ebel GD, Kuan G, Balmaseda A, Jaenisch T, Marques ETA, Brault AC, Harris E, Foy BD, Quackenbush SL, Perera R, Rovnak J. PMID: 28469032; PMCID: PMC5654541.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    46. Lysosomal cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex. Science. 2017 03 24; 355(6331):1306-1311. Castellano BM, Thelen AM, Moldavski O, Feltes M, van der Welle RE, Mydock-McGrane L, Jiang X, van Eijkeren RJ, Davis OB, Louie SM, Perera RM, Covey DF, Nomura DK, Ory DS, Zoncu R. PMID: 28336668; PMCID: PMC5823611.
      View in: PubMed   Mentions: 325     Fields:    Translation:HumansAnimalsCells
    47. Vector Competence of American Mosquitoes for Three Strains of Zika Virus. PLoS Negl Trop Dis. 2016 Oct; 10(10):e0005101. Weger-Lucarelli J, Rückert C, Chotiwan N, Nguyen C, Garcia Luna SM, Fauver JR, Foy BD, Perera R, Black WC, Kading RC, Ebel GD. PMID: 27783679; PMCID: PMC5081193.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    48. Beige Adipocyte Maintenance Is Regulated by Autophagy-Induced Mitochondrial Clearance. Cell Metab. 2016 09 13; 24(3):402-419. Altshuler-Keylin S, Shinoda K, Hasegawa Y, Ikeda K, Hong H, Kang Q, Yang Y, Perera RM, Debnath J, Kajimura S. PMID: 27568548; PMCID: PMC5023491.
      View in: PubMed   Mentions: 202     Fields:    Translation:AnimalsCells
    49. The Lysosome as a Regulatory Hub. Annu Rev Cell Dev Biol. 2016 10 06; 32:223-253. Perera RM, Zoncu R. PMID: 27501449; PMCID: PMC9345128.
      View in: PubMed   Mentions: 330     Fields:    Translation:HumansAnimalsCells
    50. Changes in the Proteome of Langat-Infected Ixodes scapularis ISE6 Cells: Metabolic Pathways Associated with Flavivirus Infection. PLoS Negl Trop Dis. 2016 Feb; 10(2):e0004180. Grabowski JM, Perera R, Roumani AM, Hedrick VE, Inerowicz HD, Hill CA, Kuhn RJ. PMID: 26859745; PMCID: PMC4747643.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    51. Pancreatic Cancer Metabolism: Breaking It Down to Build It Back Up. Cancer Discov. 2015 Dec; 5(12):1247-61. Perera RM, Bardeesy N. PMID: 26534901; PMCID: PMC4687899.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimalsCells
    52. Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Nature. 2015 Aug 20; 524(7565):361-5. Perera RM, Stoykova S, Nicolay BN, Ross KN, Fitamant J, Boukhali M, Lengrand J, Deshpande V, Selig MK, Ferrone CR, Settleman J, Stephanopoulos G, Dyson NJ, Zoncu R, Ramaswamy S, Haas W, Bardeesy N. PMID: 26168401; PMCID: PMC5086585.
      View in: PubMed   Mentions: 513     Fields:    Translation:HumansAnimalsCells
    53. YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression. Cell Rep. 2015 Mar 17; 10(10):1692-1707. Fitamant J, Kottakis F, Benhamouche S, Tian HS, Chuvin N, Parachoniak CA, Nagle JM, Perera RM, Lapouge M, Deshpande V, Zhu AX, Lai A, Min B, Hoshida Y, Avruch J, Sia D, Campreciós G, McClatchey AI, Llovet JM, Morrissey D, Raj L, Bardeesy N. PMID: 25772357; PMCID: PMC4565791.
      View in: PubMed   Mentions: 151     Fields:    
    54. Stromal response to Hedgehog signaling restrains pancreatic cancer progression. Proc Natl Acad Sci U S A. 2014 Jul 29; 111(30):E3091-100. Lee JJ, Perera RM, Wang H, Wu DC, Liu XS, Han S, Fitamant J, Jones PD, Ghanta KS, Kawano S, Nagle JM, Deshpande V, Boucher Y, Kato T, Chen JK, Willmann JK, Bardeesy N, Beachy PA. PMID: 25024225; PMCID: PMC4121834.
      View in: PubMed   Mentions: 321     Fields:    Translation:HumansAnimalsCells
    55. CDK4/6 and IGF1 receptor inhibitors synergize to suppress the growth of p16INK4A-deficient pancreatic cancers. Cancer Res. 2014 Jul 15; 74(14):3947-58. Heilmann AM, Perera RM, Ecker V, Nicolay BN, Bardeesy N, Benes CH, Dyson NJ. PMID: 24986516; PMCID: PMC4122288.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    56. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. Nature. 2013 Apr 04; 496(7443):101-5. Son J, Lyssiotis CA, Ying H, Wang X, Hua S, Ligorio M, Perera RM, Ferrone CR, Mullarky E, Shyh-Chang N, Kang Y, Fleming JB, Bardeesy N, Asara JM, Haigis MC, DePinho RA, Cantley LC, Kimmelman AC. PMID: 23535601; PMCID: PMC3656466.
      View in: PubMed   Mentions: 1179     Fields:    Translation:HumansCells
    57. Ready, set, go: the EGF receptor at the pancreatic cancer starting line. Cancer Cell. 2012 Sep 11; 22(3):281-2. Perera RM, Bardeesy N. PMID: 22975369; PMCID: PMC3564545.
      View in: PubMed   Mentions: 16     Fields:    
    58. On oncogenes and tumor suppressor genes in the mammary gland. Cold Spring Harb Perspect Biol. 2012 Jun 01; 4(6). Perera RM, Bardeesy N. PMID: 22661637; PMCID: PMC3367547.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    59. Cancer: when antioxidants are bad. Nature. 2011 Jul 06; 475(7354):43-4. Perera RM, Bardeesy N. PMID: 21734699.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    60. The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics. J Cell Biol. 2010 Aug 09; 190(3):307-15. Nakatsu F, Perera RM, Lucast L, Zoncu R, Domin J, Gertler FB, Toomre D, De Camilli P. PMID: 20679431; PMCID: PMC2922640.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    61. A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers. Cancer Res. 2010 Mar 15; 70(6):2158-64. Rothenberg SM, Mohapatra G, Rivera MN, Winokur D, Greninger P, Nitta M, Sadow PM, Sooriyakumar G, Brannigan BW, Ulman MJ, Perera RM, Wang R, Tam A, Ma XJ, Erlander M, Sgroi DC, Rocco JW, Lingen MW, Cohen EE, Louis DN, Settleman J, Haber DA. PMID: 20215515; PMCID: PMC2881662.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    62. Mechanistic Insights into Membrane Remodeling Through BAR-Domain Proteins. The FASEB Journal. 2009 Apr 1; 23:82.2-82.2. Frost FA, Mim MC, Perera PR, Spasov SK, Egelman EE, De Camilli DP, Unger UV. .
      View in: Publisher Site   Mentions:
    63. A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes. Cell. 2009 Mar 20; 136(6):1110-21. Zoncu R, Perera RM, Balkin DM, Pirruccello M, Toomre D, De Camilli P. PMID: 19303853; PMCID: PMC2705806.
      View in: PubMed   Mentions: 196     Fields:    Translation:AnimalsCells
    64. Structural basis of membrane invagination by F-BAR domains. Cell. 2008 Mar 07; 132(5):807-17. Frost A, Perera R, Roux A, Spasov K, Destaing O, Egelman EH, De Camilli P, Unger VM. PMID: 18329367; PMCID: PMC2384079.
      View in: PubMed   Mentions: 313     Fields:    Translation:HumansAnimalsCells
    65. Internalization, intracellular trafficking, and biodistribution of monoclonal antibody 806: a novel anti-epidermal growth factor receptor antibody. Neoplasia. 2007 Dec; 9(12):1099-110. Perera RM, Zoncu R, Johns TG, Pypaert M, Lee FT, Mellman I, Old LJ, Toomre DK, Scott AM. PMID: 18084617; PMCID: PMC2134906.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    66. The efficacy of epidermal growth factor receptor-specific antibodies against glioma xenografts is influenced by receptor levels, activation status, and heterodimerization. Clin Cancer Res. 2007 Mar 15; 13(6):1911-25. Johns TG, Perera RM, Vernes SC, Vitali AA, Cao DX, Cavenee WK, Scott AM, Furnari FB. PMID: 17363548.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    67. Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate. Proc Natl Acad Sci U S A. 2007 Mar 06; 104(10):3793-8. Zoncu R, Perera RM, Sebastian R, Nakatsu F, Chen H, Balla T, Ayala G, Toomre D, De Camilli PV. PMID: 17360432; PMCID: PMC1805489.
      View in: PubMed   Mentions: 151     Fields:    Translation:HumansAnimalsCells
    68. Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages. Proc Natl Acad Sci U S A. 2006 Dec 19; 103(51):19332-7. Perera RM, Zoncu R, Lucast L, De Camilli P, Toomre D. PMID: 17158794; PMCID: PMC1693868.
      View in: PubMed   Mentions: 98     Fields:    Translation:AnimalsCells
    69. Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor-specific antibody generates enhanced antitumor activity. Clin Cancer Res. 2005 Sep 01; 11(17):6390-9. Perera RM, Narita Y, Furnari FB, Gan HK, Murone C, Ahlkvist M, Luwor RB, Burgess AW, Stockert E, Jungbluth AA, Old LJ, Cavenee WK, Scott AM, Johns TG. PMID: 16144944.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    70. The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR. Oncogene. 2004 Aug 12; 23(36):6095-104. Luwor RB, Zhu HJ, Walker F, Vitali AA, Perera RM, Burgess AW, Scott AM, Johns TG. PMID: 15221011.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    71. Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478. Proc Natl Acad Sci U S A. 2003 Dec 23; 100(26):15871-6. Johns TG, Luwor RB, Murone C, Walker F, Weinstock J, Vitali AA, Perera RM, Jungbluth AA, Stockert E, Old LJ, Nice EC, Burgess AW, Scott AM. PMID: 14676326; PMCID: PMC307660.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
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