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Shomyseh Sanjabi, PhD

TitleAssociate Professor
InstitutionUniversity of California San Francisco
DepartmentMicrobiology and Immunology
Address1650 Owens St
San Francisco CA 94107
Phone415-734-4814
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    Collapse Biography 
    Collapse Education and Training
    University of California, Los AngelesBS1997Microbiology and Molecular Genetics
    University of California, Los AngelesPhD2003Microbiology, Immunology, and Molecular Genetics
    Yale UniversityPostdoctoral 2010Immunobiology

    Collapse Research 
    Collapse Research Activities and Funding
    Characterizing HIV latent reservoir in vivo
    NIH DP2AI112244Sep 30, 2013 - Aug 31, 2018
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Hogan LE, Vasquez J, Hobbs KS, Hanhauser E, Aguilar-Rodriguez B, Hussien R, Thanh C, Gibson EA, Carvidi AB, Smith LCB, Khan S, Trapecar M, Sanjabi S, Somsouk M, Stoddart CA, Kuritzkes DR, Deeks SG, Henrich TJ. Increased HIV-1 transcriptional activity and infectious burden in peripheral blood and gut-associated CD4+ T cells expressing CD30. PLoS Pathog. 2018 Feb; 14(2):e1006856. PMID: 29470552.
      View in: PubMed
    2. Trapecar M, Khan S, Cohn BL, Wu F, Sanjabi S. B cells are the predominant mediators of early systemic viral dissemination during rectal LCMV infection. Mucosal Immunol. 2018 Feb 19. PMID: 29456247.
      View in: PubMed
    3. Trapecar M, Khan S, Roan NR, Chen TH, Telwatte S, Deswal M, Pao M, Somsouk M, Deeks SG, Hunt PW, Yukl S, Sanjabi S. An Optimized and Validated Method for Isolation and Characterization of Lymphocytes from HIV+ Human Gut Biopsies. AIDS Res Hum Retroviruses. 2017 Nov; 33(S1):S31-S39. PMID: 28882052.
      View in: PubMed
    4. Khan S, Telwatte S, Trapecar M, Yukl S, Sanjabi S. Differentiating Immune Cell Targets in Gut-Associated Lymphoid Tissue for HIV Cure. AIDS Res Hum Retroviruses. 2017 Nov; 33(S1):S40-S58. PMID: 28882067.
      View in: PubMed
    5. Shehata HM, Murphy AJ, Lee MKS, Gardiner CM, Crowe SM, Sanjabi S, Finlay DK, Palmer CS. Sugar or Fat?-Metabolic Requirements for Immunity to Viral Infections. Front Immunol. 2017; 8:1311. PMID: 29085369.
      View in: PubMed
    6. Sharpton T, Lyalina S, Luong J, Pham J, Deal EM, Armour C, Gaulke C, Sanjabi S, Pollard KS. Development of Inflammatory Bowel Disease Is Linked to a Longitudinal Restructuring of the Gut Metagenome in Mice. mSystems. 2017 Sep-Oct; 2(5). PMID: 28904997.
      View in: PubMed
    7. Sanjabi S, Oh SA, Li MO. Regulation of the Immune Response by TGF-ß: From Conception to Autoimmunity and Infection. Cold Spring Harb Perspect Biol. 2017 Jun 01; 9(6). PMID: 28108486.
      View in: PubMed
    8. Khan S, Woodruff EM, Trapecar M, Fontaine KA, Ezaki A, Borbet TC, Ott M, Sanjabi S. Dampened antiviral immunity to intravaginal exposure to RNA viral pathogens allows enhanced viral replication. J Exp Med. 2016 Dec 12; 213(13):2913-2929. PMID: 27852793.
      View in: PubMed
    9. Ishigame H, Mosaheb MM, Sanjabi S, Flavell RA. Truncated form of TGF-ßRII, but not its absence, induces memory CD8+ T cell expansion and lymphoproliferative disorder in mice. J Immunol. 2013 Jun 15; 190(12):6340-50. PMID: 23686479; PMCID: PMC3690649.
      View in: PubMed, PubMed Central
    10. Ishigame H, Zenewicz LA, Sanjabi S, Licona-Limón P, Nakayama M, Leonard WJ, Flavell RA. Excessive Th1 responses due to the absence of TGF-ß signaling cause autoimmune diabetes and dysregulated Treg cell homeostasis. Proc Natl Acad Sci U S A. 2013 Apr 23; 110(17):6961-6. PMID: 23569233; PMCID: PMC3637710.
      View in: PubMed, PubMed Central
    11. Flavell RA, Sanjabi S, Wrzesinski SH, Licona-Limón P. The polarization of immune cells in the tumour environment by TGFbeta. Nat Rev Immunol. 2010 Aug; 10(8):554-67. PMID: 20616810; PMCID: PMC3885992.
      View in: PubMed, PubMed Central
    12. Sanjabi S, Flavell RA. Interaction between TGFbeta and the common gamma chain cytokines during an inflammatory immune response. Cell Cycle. 2010 Feb 01; 9(3):428-30. PMID: 20107324.
      View in: PubMed
    13. Sanjabi S, Flavell RA. Overcoming the hurdles in using mouse genetic models that block TGF-beta signaling. J Immunol Methods. 2010 Feb 28; 353(1-2):111-4. PMID: 20060833; PMCID: PMC2845397.
      View in: PubMed, PubMed Central
    14. Sanjabi S, Mosaheb MM, Flavell RA. Opposing effects of TGF-beta and IL-15 cytokines control the number of short-lived effector CD8+ T cells. Immunity. 2009 Jul 17; 31(1):131-44. PMID: 19604492; PMCID: PMC2765785.
      View in: PubMed, PubMed Central
    15. Matza D, Badou A, Jha MK, Willinger T, Antov A, Sanjabi S, Kobayashi KS, Marchesi VT, Flavell RA. Requirement for AHNAK1-mediated calcium signaling during T lymphocyte cytolysis. Proc Natl Acad Sci U S A. 2009 Jun 16; 106(24):9785-90. PMID: 19497879; PMCID: PMC2701053.
      View in: PubMed, PubMed Central
    16. Sanjabi S, Zenewicz LA, Kamanaka M, Flavell RA. Anti-inflammatory and pro-inflammatory roles of TGF-beta, IL-10, and IL-22 in immunity and autoimmunity. Curr Opin Pharmacol. 2009 Aug; 9(4):447-53. PMID: 19481975; PMCID: PMC2755239.
      View in: PubMed, PubMed Central
    17. Wang J, Wang X, Hussain S, Zheng Y, Sanjabi S, Ouaaz F, Beg AA. Distinct roles of different NF-kappa B subunits in regulating inflammatory and T cell stimulatory gene expression in dendritic cells. J Immunol. 2007 Jun 01; 178(11):6777-88. PMID: 17513725.
      View in: PubMed
    18. Li MO, Sanjabi S, Flavell RA. Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms. Immunity. 2006 Sep; 25(3):455-71. PMID: 16973386.
      View in: PubMed
    19. Kriegel MA, Li MO, Sanjabi S, Wan YY, Flavell RA. Transforming growth factor-beta: recent advances on its role in immune tolerance. Curr Rheumatol Rep. 2006 Apr; 8(2):138-44. PMID: 16569373.
      View in: PubMed
    20. Li MO, Wan YY, Sanjabi S, Robertson AK, Flavell RA. Transforming growth factor-beta regulation of immune responses. Annu Rev Immunol. 2006; 24:99-146. PMID: 16551245.
      View in: PubMed
    21. Dong C, Sanjabi S, Eynon E. Gene regulation and function: its rocking science. Immunity. 2005 Dec; 23(6):557-60. PMID: 16392168.
      View in: PubMed
    22. Sanjabi S, Williams KJ, Saccani S, Zhou L, Hoffmann A, Ghosh G, Gerondakis S, Natoli G, Smale ST. A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation. Genes Dev. 2005 Sep 15; 19(18):2138-51. PMID: 16166378; PMCID: PMC1221885.
      View in: PubMed, PubMed Central
    23. Weinmann AS, Mitchell DM, Sanjabi S, Bradley MN, Hoffmann A, Liou HC, Smale ST. Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event. Nat Immunol. 2001 Jan; 2(1):51-7. PMID: 11135578.
      View in: PubMed
    24. Sanjabi S, Hoffmann A, Liou HC, Baltimore D, Smale ST. Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages. Proc Natl Acad Sci U S A. 2000 Nov 07; 97(23):12705-10. PMID: 11058167; PMCID: PMC18828.
      View in: PubMed, PubMed Central
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