Jennifer Garrison, PhD

Title(s)Assistant Professor, Cellular Molecular Pharmacology
SchoolSchool of Medicine
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPhD2007Chemistry and Chemical Biology
    University of California, BerkeleyBA1998Molecular Cell Biology
    Collapse Awards and Honors
    NIGMS2016  - 2021Maximizing Investigators’ Research Award (MIRA) for New Investigators
    American Federation of Aging Research2016  - 2018Junior Faculty Award
    McKnight Foundation2016Finalist, Technological Innovations in Neuroscience Award
    Allen Institute for Brain Science 2015  - 2018Next Generation Leaders Advisory Council
    Alfred P. Sloan Foundation2014  - 2016Research Fellowship in Neuroscience
    Glenn Foundation2014Award for Research in Biological Mechanisms of Aging
    NIGMS2013  - 2016R00 Pathway to Independence Award
    NIGMS2010K99 Pathway to Independence Award
    Helen Hay Whitney Foundation2008  - 2010Postdoctoral Fellowship
    The Rockefeller University2007  - 2009Harvey Karp Discovery Award
    Chemical Biology in the Bay Area Symposium2006Andrew Braisted Poster Award
    Achievement Rewards for College Scientists (ARCS) Foundation 2005  - 2006Predoctoral Fellowship
    National Science Foundation2002  - 2005Predoctoral Fellowship

    Collapse Research 
    Collapse Research Activities and Funding
    High-resolution, genome-scale mapping of natural variation between reproductively isolated individuals
    NIH R01GM120430May 15, 2017 - Feb 28, 2021
    Role: Co-Investigator
    Cellular and Circuit Mechanisms of Neuropeptide Signaling
    NIH/NIGMS R35GM119828Aug 1, 2016 - May 31, 2021
    Role: Principal Investigator
    COPAS FP-PRO 500 Flow Cytometer
    NIH S10OD021686Mar 1, 2016 - Feb 28, 2017
    Role: Principal Investigator
    Neuropeptide modulation of behavior in C. elegans
    NIH/NIGMS R00GM092859May 1, 2010 - Jul 31, 2016
    Role: Principal Investigator
    Neuropeptide modulation of behavior in C. elegans
    NIH/NIGMS K99GM092859May 1, 2010 - Apr 30, 2013
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse In The News
    Collapse Twitter

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Garrison JL, Knight ZA. Linking smell to metabolism and aging. Science. 2017 11 10; 358(6364):718-719. PMID: 29123049.
      View in: PubMed
    2. Knight ZA, Tan K, Birsoy K, Schmidt S, Garrison JL, Wysocki RW, Emiliano A, Ekstrand MI, Friedman JM. Molecular profiling of activated neurons by phosphorylated ribosome capture. Cell. 2012 Nov 21; 151(5):1126-37. PMID: 23178128; PMCID: PMC3839252.
    3. Garrison JL, Macosko EZ, Bernstein S, Pokala N, Albrecht DR, Bargmann CI. Oxytocin/vasopressin-related peptides have an ancient role in reproductive behavior. Science. 2012 Oct 26; 338(6106):540-3. PMID: 23112335; PMCID: PMC3597094.
    4. Lakkaraju AK, Thankappan R, Mary C, Garrison JL, Taunton J, Strub K. Efficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocation. Mol Biol Cell. 2012 Jul; 23(14):2712-22. PMID: 22648169; PMCID: PMC3395660.
    5. Maifeld SV, MacKinnon AL, Garrison JL, Sharma A, Kunkel EJ, Hegde RS, Taunton J. Secretory protein profiling reveals TNF-a inactivation by selective and promiscuous Sec61 modulators. Chem Biol. 2011 Sep 23; 18(9):1082-8. PMID: 21944747; PMCID: PMC3855466.
    6. McGrath PT, Xu Y, Ailion M, Garrison JL, Butcher RA, Bargmann CI. Parallel evolution of domesticated Caenorhabditis species targets pheromone receptor genes. Nature. 2011 Aug 17; 477(7364):321-5. PMID: 21849976; PMCID: PMC3257054.
    7. Bautista DM, Sigal YM, Milstein AD, Garrison JL, Zorn JA, Tsuruda PR, Nicoll RA, Julius D. Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels. Nat Neurosci. 2008 Jul; 11(7):772-9. PMID: 18568022; PMCID: PMC3072296.
    8. MacKinnon AL, Garrison JL, Hegde RS, Taunton J. Photo-leucine incorporation reveals the target of a cyclodepsipeptide inhibitor of cotranslational translocation. J Am Chem Soc. 2007 Nov 28; 129(47):14560-1. PMID: 17983236; PMCID: PMC2574519.
    9. Knight ZA, Garrison JL, Chan K, King DS, Shokat KM. A remodelled protease that cleaves phosphotyrosine substrates. J Am Chem Soc. 2007 Sep 26; 129(38):11672-3. PMID: 17803306; PMCID: PMC2932698.
    10. Rutkowski DT, Kang SW, Goodman AG, Garrison JL, Taunton J, Katze MG, Kaufman RJ, Hegde RS. The role of p58IPK in protecting the stressed endoplasmic reticulum. Mol Biol Cell. 2007 Sep; 18(9):3681-91. PMID: 17567950.
      View in: PubMed
    11. Kang SW, Rane NS, Kim SJ, Garrison JL, Taunton J, Hegde RS. Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway. Cell. 2006 Dec 01; 127(5):999-1013. PMID: 17129784; PMCID: PMC3656606.
    12. Oyadomari S, Yun C, Fisher EA, Kreglinger N, Kreibich G, Oyadomari M, Harding HP, Goodman AG, Harant H, Garrison JL, Taunton J, Katze MG, Ron D. Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload. Cell. 2006 Aug 25; 126(4):727-39. PMID: 16923392.
      View in: PubMed
    13. Horak E, Heitner T, Robinson MK, Simmons HH, Garrison J, Russeva M, Furmanova P, Lou J, Zhou Y, Yuan QA, Weiner LM, Adams GP, Marks JD. Isolation of scFvs to in vitro produced extracellular domains of EGFR family members. Cancer Biother Radiopharm. 2005 Dec; 20(6):603-13. PMID: 16398612.
      View in: PubMed
    14. Garrison JL, Kunkel EJ, Hegde RS, Taunton J. A substrate-specific inhibitor of protein translocation into the endoplasmic reticulum. Nature. 2005 Jul 14; 436(7048):285-9. PMID: 16015336.
      View in: PubMed
    15. Heitner T, Moor A, Garrison JL, Marks C, Hasan T, Marks JD. Selection of cell binding and internalizing epidermal growth factor receptor antibodies from a phage display library. J Immunol Methods. 2001 Feb 01; 248(1-2):17-30. PMID: 11223066.
      View in: PubMed
    16. Gordon L, Garrison JL, Cheng JC, Liu YK, Nathan RP, Levinsohn DG. Biomechanical analysis of a step-cut technique for flexor tendon repair. J Hand Surg Br. 1992 Jun; 17(3):282-5. PMID: 1624861.
      View in: PubMed