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Jorge Kizer, MD

TitleProfessor & Section Chief
InstitutionUniversity of California San Francisco
DepartmentMedicine
Address
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    Collapse Biography 
    Collapse Education and Training
    University of Pennsylvania School of Medicine, Philadelphia, PAMD1994Medicine
    Brigham and Women's Hospital, Boston, MA1997Internal Medicine
    Harvard School of Public Health, Boston, MAMSc1999Epidemiology
    University of Pennsylvania Health System, Philadelphia, PA2001Cardiovascular Medicine

    Collapse Overview 
    Collapse Overview
    My research program seeks to advance understanding of risk factors for heart disease and stroke in order to improve prevention, risk stratification, and treatment of these disorders. These investigations leverage molecular epidemiology and cardiovascular imaging to identify biochemical markers and endophenotypes involved in the initiation, development and progression of cardiovascular diseases.

    My work involves various NIH-funded longitudinal cohort studies, including the Cardiovascular Health Study, the Strong Heart Study, the Multi-Ethnic Study of Atherosclerosis, the Hispanic Community Heath Study / Study of Latinos, and the Women’s Interagency HIV Study. A major focus is the interrelationship of glucose and lipid metabolism, bone and mineral disease, and cardiovascular disorders, particularly in the context of aging and HIV. A new thrust is the application of next-generation sequencing technologies and advances in non-invasive imaging to make inroads into pathophysiology and potential therapeutics.


    Collapse Research 
    Collapse Research Activities and Funding
    Advanced Glycation Endproducts and Cardio-Renal Disease
    NIH/NHLBI K24HL135413Jul 15, 2017 - Jun 30, 2022
    Role: Principal Investigator
    Comprehensive Evaluation of Aging-Related Clinical Outcomes and Geroproteins
    NIH/NIA R01AG052964Jun 1, 2016 - May 31, 2021
    Role: Co-Principal Investigator
    Evaluation of HIV-associated Cardiac Dysfunction in Women
    NIH/NHLBI R01HL132794Apr 1, 2016 - Mar 31, 2020
    Role: Principal Investigator
    Determinants and Cardiovascular Consequences of Diabetes in Older Adults
    NIH/NHLBI R01HL094555Sep 1, 2009 - Jun 30, 2014
    Role: Co-Principal Investigator
    Thrombophilia In Cryptogenic Stroke (THICK) Study
    NIH/NHLBI K23HL070854Sep 1, 2002 - Aug 31, 2009
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Moon JY, Zolnik CP, Wang Z, Qiu Y, Usyk M, Wang T, Kizer JR, Landay AL, Kurland IJ, Anastos K, Kaplan RC, Burk RD, Qi Q. Gut microbiota and plasma metabolites associated with diabetes in women with, or at high risk for, HIV infection. EBioMedicine. 2018 Oct 23. PMID: 30366816.
      View in: PubMed
    2. Duprez DA, Heckbert SR, Alonso A, Gross MD, Ix JH, Kizer JR, Tracy RP, Kronmal R, Jacobs DR. Collagen Biomarkers and Incidence of New Onset of Atrial Fibrillation in Subjects With No Overt Cardiovascular Disease at Baseline. Circ Arrhythm Electrophysiol. 2018 Oct; 11(10):e006557. PMID: 30354407.
      View in: PubMed
    3. Fujikura K, Peltzer B, Tiwari N, Shim HG, Dinhofer AB, Shitole SG, Kizer JR, Garcia MJ. Reduced global longitudinal strain is associated with increased risk of cardiovascular events or death after kidney transplant. Int J Cardiol. 2018 Jul 22. PMID: 30082119.
      View in: PubMed
    4. Massera D, Biggs ML, Walker MD, Mukamal KJ, Ix JH, Djousse L, Valderrábano RJ, Siscovick DS, Tracy RP, Xue X, Kizer JR. Biochemical Markers of Bone Turnover and Risk of Incident Diabetes in Older Women: The Cardiovascular Health Study. Diabetes Care. 2018 Jul 12. PMID: 30002202.
      View in: PubMed
    5. Tsao CW, Lyass A, Enserro D, Larson MG, Ho JE, Kizer JR, Gottdiener JS, Psaty BM, Vasan RS. Temporal Trends in the Incidence of and Mortality Associated With Heart Failure With Preserved and Reduced Ejection Fraction. JACC Heart Fail. 2018 Aug; 6(8):678-685. PMID: 30007560.
      View in: PubMed
    6. Savji N, Meijers WC, Bartz TM, Bhambhani V, Cushman M, Nayor M, Kizer JR, Sarma A, Blaha MJ, Gansevoort RT, Gardin JM, Hillege HL, Ji F, Kop WJ, Lau ES, Lee DS, Sadreyev R, van Gilst WH, Wang TJ, Zanni MV, Vasan RS, Allen NB, Psaty BM, van der Harst P, Levy D, Larson M, Shah SJ, de Boer RA, Gottdiener JS, Ho JE. The Association of Obesity and Cardiometabolic Traits With Incident HFpEF and HFrEF. JACC Heart Fail. 2018 Aug; 6(8):701-709. PMID: 30007554.
      View in: PubMed
    7. Duprez DA, Gross MD, Ix JH, Kizer JR, Tracy RP, Shea S, Jacobs DR. Collagen biomarkers predict new onset of hypertension in normotensive participants: the Multi-Ethnic Study of Atherosclerosis. J Hypertens. 2018 May 17. PMID: 29782392.
      View in: PubMed
    8. Sanders JL, Arnold AM, Boudreau RM, Hirsch CH, Kizer JR, Kaplan RC, Cappola AR, Cushman M, Jacob ME, Kritchevsky SB, Newman AB. Association of biomarker and physiologic indices with mortality in older adults: Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci. 2018 Apr 12. PMID: 29659743.
      View in: PubMed
    9. Huck DM, Hanna DB, Rubin LH, Maki P, Valcour V, Springer G, Xue X, Lazar J, Hodis HN, Anastos K, Kaplan RC, Kizer JR. Carotid Artery Stiffness And Cognitive Decline Among Women With Or At Risk For Hiv Infection. J Acquir Immune Defic Syndr. 2018 Mar 23. PMID: 29578932.
      View in: PubMed
    10. Kundel V, Trivieri MG, Karakatsanis NA, Robson PM, Mani V, Kizer JR, Kaplan R, Fayad Z, Shah N. Assessment of atherosclerotic plaque activity in patients with sleep apnea using hybrid positron emission tomography/magnetic resonance imaging (PET/MRI): a feasibility study. Sleep Breath. 2018 Mar 05. PMID: 29508121.
      View in: PubMed
    11. Garg PK, Biggs ML, Kaplan R, Kizer JR, Heckbert SR, Mukamal KJ. Fasting and post-glucose load measures of insulin resistance and risk of incident atrial fibrillation: The Cardiovascular Health Study. Nutr Metab Cardiovasc Dis. 2018 Jul; 28(7):716-721. PMID: 29615289.
      View in: PubMed
    12. de Boer RA, Nayor M, deFilippi CR, Enserro D, Bhambhani V, Kizer JR, Blaha MJ, Brouwers FP, Cushman M, Lima JAC, Bahrami H, van der Harst P, Wang TJ, Gansevoort RT, Fox CS, Gaggin HK, Kop WJ, Liu K, Vasan RS, Psaty BM, Lee DS, Hillege HL, Bartz TM, Benjamin EJ, Chan C, Allison M, Gardin JM, Januzzi JL, Shah SJ, Levy D, Herrington DM, Larson MG, van Gilst WH, Gottdiener JS, Bertoni AG, Ho JE. Association of Cardiovascular Biomarkers With Incident Heart Failure With Preserved and Reduced Ejection Fraction. JAMA Cardiol. 2018 Mar 01; 3(3):215-224. PMID: 29322198.
      View in: PubMed
    13. Duprez DA, Gross MD, Kizer JR, Ix JH, Hundley WG, Jacobs DR. Predictive Value of Collagen Biomarkers for Heart Failure With and Without Preserved Ejection Fraction: MESA (Multi-Ethnic Study of Atherosclerosis). J Am Heart Assoc. 2018 Feb 23; 7(5). PMID: 29475876.
      View in: PubMed
    14. Mukamal KJ, Siscovick DS, de Boer IH, Ix JH, Kizer JR, Djoussé L, Fitzpatrick AL, Tracy RP, Boyko EJ, Kahn SE, Arnold AM. Metabolic Clusters and Outcomes in Older Adults: The Cardiovascular Health Study. J Am Geriatr Soc. 2018 Feb; 66(2):289-296. PMID: 29431855.
      View in: PubMed
    15. Bhambhani V, Kizer JR, Lima JAC, van der Harst P, Bahrami H, Nayor M, de Filippi CR, Enserro D, Blaha MJ, Cushman M, Wang TJ, Gansevoort RT, Fox CS, Gaggin HK, Kop WJ, Liu K, Vasan RS, Psaty BM, Lee DS, Brouwers FP, Hillege HL, Bartz TM, Benjamin EJ, Chan C, Allison M, Gardin JM, Januzzi JL, Levy D, Herrington DM, van Gilst WH, Bertoni AG, Larson MG, de Boer RA, Gottdiener JS, Shah SJ, Ho JE. Predictors and outcomes of heart failure with mid-range ejection fraction. Eur J Heart Fail. 2018 Apr; 20(4):651-659. PMID: 29226491.
      View in: PubMed
    16. Garg PK, Bartz TM, Norby FL, Jorgensen NW, McClelland RL, Ballantyne CM, Chen LY, Gottdiener JS, Greenland P, Hoogeveen R, Jenny NS, Kizer JR, Rosenson RS, Soliman EZ, Cushman M, Alonso A, Heckbert SR. Association of lipoprotein-associated phospholipase A2 and risk of incident atrial fibrillation: Findings from 3 cohorts. Am Heart J. 2018 Mar; 197:62-69. PMID: 29447785.
      View in: PubMed
    17. Gupta T, Goel K, Kolte D, Khera S, Villablanca PA, Aronow WS, Bortnick AE, Slovut DP, Taub CC, Kizer JR, Pyo RT, Abbott JD, Fonarow GC, Rihal CS, Garcia MJ, Bhatt DL. Association of Chronic Kidney Disease With In-Hospital Outcomes of Transcatheter Aortic Valve Replacement. JACC Cardiovasc Interv. 2017 Oct 23; 10(20):2050-2060. PMID: 29050621.
      View in: PubMed
    18. Cao J, Steffen BT, Guan W, Budoff M, Michos ED, Kizer JR, Post WS, Tsai MY. Evaluation of Lipoprotein(a) Electrophoretic and Immunoassay Methods in Discriminating Risk of Calcific Aortic Valve Disease and Incident Coronary Heart Disease: The Multi-Ethnic Study of Atherosclerosis. Clin Chem. 2017 Nov; 63(11):1705-1713. PMID: 28904058.
      View in: PubMed
    19. Forman DE, Santanasto AJ, Boudreau R, Harris T, Kanaya AM, Satterfield S, Simonsick EM, Butler J, Kizer JR, Newman AB. Impact of Incident Heart Failure on Body Composition Over Time in the Health, Aging, and Body Composition Study Population. Circ Heart Fail. 2017 Sep; 10(9). PMID: 28899988.
      View in: PubMed
    20. Villablanca PA, Holmes D, Mohananey D, Briceno DF, Núñez Gil IJ, Kargoli F, Gupta T, Kizer JR, Bortnick AE, Wiley J, Menegus MA, Pyo R, García M, Ramakrishna H, Mookadam F. Direct Xa inhibitors in addition to antiplatelet therapy in acute coronary syndrome: meta-analysis of randomized trials. Coron Artery Dis. 2017 Aug; 28(5):395-405. PMID: 28328784.
      View in: PubMed
    21. Bodapati RK, Kizer JR, Kop WJ, Kamel H, Stein PK. Addition of 24-Hour Heart Rate Variability Parameters to the Cardiovascular Health Study Stroke Risk Score and Prediction of Incident Stroke: The Cardiovascular Health Study. J Am Heart Assoc. 2017 Jul 21; 6(7). PMID: 28733431.
      View in: PubMed
    22. Jensen MK, Jensen RA, Mukamal KJ, Guo X, Yao J, Sun Q, Cornelis M, Liu Y, Chen MH, Kizer JR, Djoussé L, Siscovick DS, Psaty BM, Zmuda JM, Rotter JI, Garcia M, Harris T, Chen I, Goodarzi MO, Nalls MA, Keller M, Arnold AM, Newman AB, Hoogeveen RC, Rexrode KM, Rimm EB, Hu FB, Ramachandran VS, Katz R, Pankow JS, Ix JH. Detection of genetic loci associated with plasma fetuin-A: a meta-analysis of genome-wide association studies from the CHARGE Consortium. Hum Mol Genet. 2017 06 01; 26(11):2156-2163. PMID: 28379451.
      View in: PubMed
    23. Massera D, Xu S, Bartz TM, Bortnick AE, Ix JH, Chonchol M, Owens DS, Barasch E, Gardin JM, Gottdiener JS, Robbins JR, Siscovick DS, Kizer JR. Relationship of bone mineral density with valvular and annular calcification in community-dwelling older people: The Cardiovascular Health Study. Arch Osteoporos. 2017 Dec; 12(1):52. PMID: 28560501.
      View in: PubMed
    24. Wang W, Zhang Y, Lee ET, Howard BV, Devereux RB, Cole SA, Best LG, Welty TK, Rhoades E, Yeh J, Ali T, Kizer JR, Kamel H, Shara N, Wiebers DO, Stoner JA. Risk Factors and Prediction of Stroke in a Population with High Prevalence of Diabetes: The Strong Heart Study. World J Cardiovasc Dis. 2017 May; 7(5):145-162. PMID: 28775914.
      View in: PubMed
    25. Duprez DA, Gross MD, Sanchez OA, Kizer JR, Ix JH, Lima J, Tracy RP, Jacobs DR. Collagen Turnover Markers in Relation to Future Cardiovascular and Noncardiovascular Disease: The Multi-Ethnic Study of Atherosclerosis. Clin Chem. 2017 Jul; 63(7):1237-1247. PMID: 28515098.
      View in: PubMed
    26. Tibuakuu M, Zhao D, de Boer IH, Guallar E, Bortnick AE, Lutsey PL, Budoff MJ, Kizer JR, Kestenbaum BR, Michos ED. Relation of Serum Vitamin D to Risk of Mitral Annular and Aortic Valve Calcium (from the Multi-Ethnic Study of Atherosclerosis). Am J Cardiol. 2017 Aug 01; 120(3):473-478. PMID: 28583687.
      View in: PubMed
    27. Aggarwal SR, Herrington DM, Vladutiu CJ, Newman JC, Swett K, Gonzalez F, Kizer JR, Kominiarek MA, Tabb KM, Gallo LC, Talavera GA, Hurwitz BE, Rodriguez CJ. Higher number of live births is associated with left ventricular diastolic dysfunction and adverse cardiac remodelling among US Hispanic/Latina women: results from the Echocardiographic Study of Latinos. Open Heart. 2017; 4(1):e000530. PMID: 28674618.
      View in: PubMed
    28. Fujikura K, Golive AD, Ando T, Corado FM, Shitole SG, Kizer JR, Shah AM, Prince MR, Spevack DM, Garcia MJ. Increased Iron Deposition Is Directly Associated With Myocardial Dysfunction in Patients With Sickle Cell Disease. JACC Cardiovasc Imaging. 2018 Feb; 11(2 Pt 1):279-280. PMID: 28412428.
      View in: PubMed
    29. Hanna DB, Xu S, Melamed ML, Gonzalez F, Allison MA, Bilsker MS, Hurwitz BE, Kansal MM, Schneiderman N, Shah SJ, Kaplan RC, Rodriguez CJ, Kizer JR. Association of Albuminuria With Cardiac Dysfunction in US Hispanics/Latinos. Am J Cardiol. 2017 Jun 15; 119(12):2073-2080. PMID: 28438309.
      View in: PubMed
    30. Mehta T, Buzkova P, Kizer JR, Djousse L, Chonchol M, Mukamal KJ, Shlipak M, Ix JH, Jalal D. Higher plasma transforming growth factor (TGF)-ß is associated with kidney disease in older community dwelling adults. BMC Nephrol. 2017 03 21; 18(1):98. PMID: 28327102.
      View in: PubMed
    31. Fohtung RB, Brown DL, Koh WJ, Bartz TM, Carbone LD, Civitelli R, Stein PK, Chaves PH, Kestenbaum BR, Kizer JR. Bone Mineral Density and Risk of Heart Failure in Older Adults: The Cardiovascular Health Study. J Am Heart Assoc. 2017 Mar 13; 6(3). PMID: 28288973.
      View in: PubMed
    32. Lee JS, Chang PY, Zhang Y, Kizer JR, Best LG, Howard BV. Triglyceride and HDL-C Dyslipidemia and Risks of Coronary Heart Disease and Ischemic Stroke by Glycemic Dysregulation Status: The Strong Heart Study. Diabetes Care. 2017 04; 40(4):529-537. PMID: 28122840.
      View in: PubMed
    33. Ahiawodzi PD, Kerber RA, Taylor KC, Groves FD, O'Brien E, Ix JH, Kizer JR, Djoussé L, Tracy RP, Newman AB, Siscovick DS, Robbins J, Mukamal K. Sleep-disordered breathing is associated with higher carboxymethyllysine level in elderly women but not elderly men in the cardiovascular health study. Biomarkers. 2017 May - Jun; 22(3-4):361-366. PMID: 28055285.
      View in: PubMed
    34. Butterfield TR, Hanna DB, Kaplan RC, Kizer JR, Durkin HG, Young MA, Nowicki MJ, Tien PC, Golub ET, Floris-Moore MA, Titanji K, Fischl MA, Heath SL, Martinson J, Crowe SM, Palmer CS, Landay AL, Anzinger JJ. Increased glucose transporter-1 expression on intermediate monocytes from HIV-infected women with subclinical cardiovascular disease. AIDS. 2017 Jan 14; 31(2):199-205. PMID: 27835618.
      View in: PubMed
    35. Kaplan RC, Strizich G, Aneke-Nash C, Dominguez-Islas C, Bužková P, Strickler H, Rohan T, Pollak M, Kuller L, Kizer JR, Cappola A, Li CI, Psaty BM, Newman A. Insulinlike Growth Factor Binding Protein-1 and Ghrelin Predict Health Outcomes Among Older Adults: Cardiovascular Health Study Cohort. J Clin Endocrinol Metab. 2017 01 01; 102(1):267-278. PMID: 27820656.
      View in: PubMed
    36. Joyce KE, Biggs ML, Djoussé L, Ix JH, Kizer JR, Siscovick DS, Shores MM, Matsumoto AM, Mukamal KJ. Testosterone, Dihydrotestosterone, Sex Hormone-Binding Globulin, and Incident Diabetes Among Older Men: The Cardiovascular Health Study. J Clin Endocrinol Metab. 2017 01 01; 102(1):33-39. PMID: 27732332.
      View in: PubMed
    37. Maurer MS, Koh WJ, Bartz TM, Vullaganti S, Barasch E, Gardin JM, Gottdiener JS, Psaty BM, Kizer JR. Relation of the Myocardial Contraction Fraction, as Calculated from M-Mode Echocardiography, With Incident Heart Failure, Atherosclerotic Cardiovascular Disease and Mortality (Results from the Cardiovascular Health Study). Am J Cardiol. 2017 Mar 15; 119(6):923-928. PMID: 28073429.
      View in: PubMed
    38. Zhang L, Segal AZ, Leifer D, Silverstein RL, Gerber LM, Devereux RB, Kizer JR. Circulating protein Z concentration, PROZ variants, and unexplained cerebral infarction in young and middle-aged adults. Thromb Haemost. 2017 01 05; 117(1):149-157. PMID: 27683756.
      View in: PubMed
    39. Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis. Lancet Diabetes Endocrinol. 2016 10; 4(10):840-9. PMID: 27599814.
      View in: PubMed
    40. Beheshtian A, Shitole SG, Segal AZ, Leifer D, Tracy RP, Rader DJ, Devereux RB, Kizer JR. Lipoprotein (a) level, apolipoprotein (a) size, and risk of unexplained ischemic stroke in young and middle-aged adults. Atherosclerosis. 2016 10; 253:47-53. PMID: 27575936.
      View in: PubMed
    41. Messé SR, Gronseth G, Kent DM, Kizer JR, Homma S, Rosterman L, Kasner SE. Practice advisory: Recurrent stroke with patent foramen ovale (update of practice parameter): Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Neurology. 2016 Aug 23; 87(8):815-21. PMID: 27466464.
      View in: PubMed
    42. Hanna DB, Ramaswamy C, Kaplan RC, Kizer JR, Anastos K, Daskalakis D, Zimmerman R, Braunstein SL. Trends in Cardiovascular Disease Mortality Among Persons With HIV in New York City, 2001-2012. Clin Infect Dis. 2016 Oct 15; 63(8):1122-1129. PMID: 27444412.
      View in: PubMed
    43. Walford GA, Gustafsson S, Rybin D, Stancáková A, Chen H, Liu CT, Hong J, Jensen RA, Rice K, Morris AP, Mägi R, Tönjes A, Prokopenko I, Kleber ME, Delgado G, Silbernagel G, Jackson AU, Appel EV, Grarup N, Lewis JP, Montasser ME, Landenvall C, Staiger H, Luan J, Frayling TM, Weedon MN, Xie W, Morcillo S, Martínez-Larrad MT, Biggs ML, Chen YD, Corbaton-Anchuelo A, Færch K, Gómez-Zumaquero JM, Goodarzi MO, Kizer JR, Koistinen HA, Leong A, Lind L, Lindgren C, Machicao F, Manning AK, Martín-Núñez GM, Rojo-Martínez G, Rotter JI, Siscovick DS, Zmuda JM, Zhang Z, Serrano-Rios M, Smith U, Soriguer F, Hansen T, Jørgensen TJ, Linnenberg A, Pedersen O, Walker M, Langenberg C, Scott RA, Wareham NJ, Fritsche A, Häring HU, Stefan N, Groop L, O'Connell JR, Boehnke M, Bergman RN, Collins FS, Mohlke KL, Tuomilehto J, März W, Kovacs P, Stumvoll M, Psaty BM, Kuusisto J, Laakso M, Meigs JB, Dupuis J, Ingelsson E, Florez JC. Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci. Diabetes. 2016 10; 65(10):3200-11. PMID: 27416945; PMCID: PMC5033262 [Available on 10/01/17].
    44. Bortnick AE, Bartz TM, Ix JH, Chonchol M, Reiner A, Cushman M, Owens D, Barasch E, Siscovick DS, Gottdiener JS, Kizer JR. Association of inflammatory, lipid and mineral markers with cardiac calcification in older adults. Heart. 2016 Jul 13. PMID: 27411840.
      View in: PubMed
    45. Spahillari A, Mukamal KJ, DeFilippi C, Kizer JR, Gottdiener JS, Djoussé L, Lyles MF, Bartz TM, Murthy VL, Shah RV. The association of lean and fat mass with all-cause mortality in older adults: The Cardiovascular Health Study. Nutr Metab Cardiovasc Dis. 2016 11; 26(11):1039-1047. PMID: 27484755.
      View in: PubMed
    46. Brutsaert EF, Biggs ML, Delaney JA, Djoussé L, Gottdiener JS, Ix JH, Kim F, Mukamal KJ, Siscovick DS, Tracy RP, de Boer IH, deFilippi CR, Kizer JR. Longitudinal assessment of N-terminal pro-B-type natriuretic peptide and risk of diabetes in older adults: The cardiovascular health study. Metabolism. 2016 10; 65(10):1489-97. PMID: 27621184.
      View in: PubMed
    47. Beasley JM, Jung M, Tasevska N, Wong WW, Siega-Riz AM, Sotres-Alvarez D, Gellman MD, Kizer JR, Shaw PA, Stamler J, Stoutenberg M, Van Horn L, Franke AA, Wylie-Rosett J, Mossavar-Rahmani Y. Biomarker-predicted sugars intake compared with self-reported measures in US Hispanics/Latinos: results from the HCHS/SOL SOLNAS study. Public Health Nutr. 2016 12; 19(18):3256-3264. PMID: 27339078.
      View in: PubMed
    48. Liu CT, Raghavan S, Maruthur N, Kabagambe EK, Hong J, Ng MC, Hivert MF, Lu Y, An P, Bentley AR, Drolet AM, Gaulton KJ, Guo X, Armstrong LL, Irvin MR, Li M, Lipovich L, Rybin DV, Taylor KD, Agyemang C, Palmer ND, Cade BE, Chen WM, Dauriz M, Delaney JA, Edwards TL, Evans DS, Evans MK, Lange LA, Leong A, Liu J, Liu Y, Nayak U, Patel SR, Porneala BC, Rasmussen-Torvik LJ, Snijder MB, Stallings SC, Tanaka T, Yanek LR, Zhao W, Becker DM, Bielak LF, Biggs ML, Bottinger EP, Bowden DW, Chen G, Correa A, Couper DJ, Crawford DC, Cushman M, Eicher JD, Fornage M, Franceschini N, Fu YP, Goodarzi MO, Gottesman O, Hara K, Harris TB, Jensen RA, Johnson AD, Jhun MA, Karter AJ, Keller MF, Kho AN, Kizer JR, Krauss RM, Langefeld CD, Li X, Liang J, Liu S, Lowe WL, Mosley TH, North KE, Pacheco JA, Peyser PA, Patrick AL, Rice KM, Selvin E, Sims M, Smith JA, Tajuddin SM, Vaidya D, Wren MP, Yao J, Zhu X, Ziegler JT, Zmuda JM, Zonderman AB, Zwinderman AH. Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin. Am J Hum Genet. 2016 Jul 07; 99(1):56-75. PMID: 27321945.
      View in: PubMed
    49. Newman AB, Sanders JL, Kizer JR, Boudreau RM, Odden MC, Zeki Al Hazzouri A, Arnold AM. Trajectories of function and biomarkers with age: the CHS All Stars Study. Int J Epidemiol. 2016 08; 45(4):1135-1145. PMID: 27272182.
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    50. Ho JE, Enserro D, Brouwers FP, Kizer JR, Shah SJ, Psaty BM, Bartz TM, Santhanakrishnan R, Lee DS, Chan C, Liu K, Blaha MJ, Hillege HL, van der Harst P, van Gilst WH, Kop WJ, Gansevoort RT, Vasan RS, Gardin JM, Levy D, Gottdiener JS, de Boer RA, Larson MG. Predicting Heart Failure With Preserved and Reduced Ejection Fraction: The International Collaboration on Heart Failure Subtypes. Circ Heart Fail. 2016 06; 9(6). PMID: 27266854.
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    51. Sanders JL, Arnold AM, Hirsch CH, Thielke SM, Kim D, Mukamal KJ, Kizer JR, Ix JH, Kaplan RC, Kritchevsky SB, Newman AB. Effects of Disease Burden and Functional Adaptation on Morbidity and Mortality on Older Adults. J Am Geriatr Soc. 2016 Jun; 64(6):1242-9. PMID: 27321602; PMCID: PMC4922749 [Available on 06/01/17].
    52. Kim F, Biggs ML, Kizer JR, Brutsaert EF, de Filippi C, Newman AB, Kronmal RA, Tracy RP, Gottdiener JS, Djoussé L, de Boer IH, Psaty BM, Siscovick DS, Mukamal KJ. Brain natriuretic peptide and insulin resistance in older adults. Diabet Med. 2017 02; 34(2):235-238. PMID: 27101535.
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    53. Karas MG, Yee LM, Biggs ML, Djoussé L, Mukamal KJ, Ix JH, Zieman SJ, Siscovick DS, Gottdiener JS, Rosenberg MA, Kronmal RA, Heckbert SR, Kizer JR. Measures of Body Size and Composition and Risk of Incident Atrial Fibrillation in Older People: The Cardiovascular Health Study. Am J Epidemiol. 2016 Jun 01; 183(11):998-1007. PMID: 27188936; PMCID: PMC4887576 [Available on 06/01/17].
    54. Taegtmeyer H, Young ME, Lopaschuk GD, Abel ED, Brunengraber H, Darley-Usmar V, Des Rosiers C, Gerszten R, Glatz JF, Griffin JL, Gropler RJ, Holzhuetter HG, Kizer JR, Lewandowski ED, Malloy CR, Neubauer S, Peterson LR, Portman MA, Recchia FA, Van Eyk JE, Wang TJ. Assessing Cardiac Metabolism: A Scientific Statement From the American Heart Association. Circ Res. 2016 May 13; 118(10):1659-701. PMID: 27012580.
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    55. González HM, Tarraf W, Rodríguez CJ, Gallo LC, Sacco RL, Talavera GA, Heiss G, Kizer JR, Hernandez R, Davis S, Schneiderman N, Daviglus ML, Kaplan RC. Cardiovascular health among diverse Hispanics/Latinos: Hispanic Community Health Study/Study of Latinos (HCHS/SOL) results. Am Heart J. 2016 Jun; 176:134-44. PMID: 27264232.
      View in: PubMed
    56. Kaplan RC, Hanna DB, Kizer JR. Recent Insights Into Cardiovascular Disease (CVD) Risk Among HIV-Infected Adults. Curr HIV/AIDS Rep. 2016 Feb; 13(1):44-52. PMID: 26910597.
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    57. Kizer JR. Adiponectin and atrial fibrillation in older adults. Heart. 2016 Feb; 102(3):254. PMID: 26769381.
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    58. Shitole SG, Kayo N, Srinivas V, Alapati V, Nordin C, Southern W, Christia P, Faillace RT, Scheuer J, Kizer JR. Clinical Profile, Acute Care, and Middle-Term Outcomes of Cocaine-Associated ST-Segment Elevation Myocardial Infarction in an Inner-City Community. Am J Cardiol. 2016 Apr 15; 117(8):1224-30. PMID: 26897639.
      View in: PubMed
    59. Harhay MO, Kizer JR, Criqui MH, Lima JA, Tracy R, Bluemke DA, Kawut SM. Adipokines and the Right Ventricle: The MESA-RV Study. PLoS One. 2015; 10(9):e0136818. PMID: 26348768; PMCID: PMC4562601.
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    130. Wormser D, Kaptoge S, Di Angelantonio E, Wood AM, Pennells L, Thompson A, Sarwar N, Kizer JR, Lawlor DA, Nordestgaard BG, Ridker P, Salomaa V, Stevens J, Woodward M, Sattar N, Collins R, Thompson SG, Whitlock G, Danesh J. Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies. Lancet. 2011 Mar 26; 377(9771):1085-95. PMID: 21397319; PMCID: PMC3145074.
    131. Kizer JR, Biggs ML, Ix JH, Mukamal KJ, Zieman SJ, de Boer IH, Mozaffarian D, Barzilay JI, Strotmeyer ES, Luchsinger JA, Elkind MS, Longstreth WT, Kuller LH, Siscovick DS. Measures of adiposity and future risk of ischemic stroke and coronary heart disease in older men and women. Am J Epidemiol. 2011 Jan 01; 173(1):10-25. PMID: 21123850; PMCID: PMC3025638.
    132. Kawut SM, Barr RG, Johnson WC, Chahal H, Tandri H, Jain A, Bristow MR, Kizer JR, Bagiella E, Lima JA, Bluemke DA. Matrix metalloproteinase-9 and plasminogen activator inhibitor-1 are associated with right ventricular structure and function: the MESA-RV Study. Biomarkers. 2010 Dec; 15(8):731-8. PMID: 20923324.
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    133. Ventetuolo CE, Ouyang P, Bluemke DA, Tandri H, Barr RG, Bagiella E, Cappola AR, Bristow MR, Johnson C, Kronmal RA, Kizer JR, Lima JA, Kawut SM. Sex hormones are associated with right ventricular structure and function: The MESA-right ventricle study. Am J Respir Crit Care Med. 2011 Mar 01; 183(5):659-67. PMID: 20889903.
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    134. Aaron CP, Tandri H, Barr RG, Johnson WC, Bagiella E, Chahal H, Jain A, Kizer JR, Bertoni AG, Lima JA, Bluemke DA, Kawut SM. Physical activity and right ventricular structure and function. The MESA-Right Ventricle Study. Am J Respir Crit Care Med. 2011 Feb 01; 183(3):396-404. PMID: 20813888.
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    135. Kizer JR, Arnold AM, Strotmeyer ES, Ives DG, Cushman M, Ding J, Kritchevsky SB, Chaves PH, Hirsch CH, Newman AB. Change in circulating adiponectin in advanced old age: determinants and impact on physical function and mortality. The Cardiovascular Health Study All Stars Study. J Gerontol A Biol Sci Med Sci. 2010 Nov; 65(11):1208-14. PMID: 20616148; PMCID: PMC2954239.
    136. Kizer JR, Madias C, Wilner B, Vaughan CJ, Mushlin AI, Trushin P, Gotto AM, Pasternak RC. Relation of different measures of low-density lipoprotein cholesterol to risk of coronary artery disease and death in a meta-regression analysis of large-scale trials of statin therapy. Am J Cardiol. 2010 May 01; 105(9):1289-96. PMID: 20403481; PMCID: PMC2917836.
    137. Roman MJ, Okin PM, Kizer JR, Lee ET, Howard BV, Devereux RB. Relations of central and brachial blood pressure to left ventricular hypertrophy and geometry: the Strong Heart Study. J Hypertens. 2010 Feb; 28(2):384-8. PMID: 20051906.
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    138. Roman MJ, Devereux RB, Kizer JR, Okin PM, Lee ET, Wang W, Umans JG, Calhoun D, Howard BV. High central pulse pressure is independently associated with adverse cardiovascular outcome the strong heart study. J Am Coll Cardiol. 2009 Oct 27; 54(18):1730-4. PMID: 19850215; PMCID: PMC3164777.
    139. Kizer JR, Krauser DG, Rodeheffer RJ, Burnett JC, Okin PM, Roman MJ, Umans JG, Best LG, Lee ET, Devereux RB. Prognostic value of multiple biomarkers in American Indians free of clinically overt cardiovascular disease (from the Strong Heart Study). Am J Cardiol. 2009 Jul 15; 104(2):247-53. PMID: 19576355; PMCID: PMC2745719.
    140. Kizer JR. Evaluation of the patient with unexplained stroke. Coron Artery Dis. 2008 Nov; 19(7):535-40. PMID: 18923251.
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    141. Zhang Y, Galloway JM, Welty TK, Wiebers DO, Whisnant JP, Devereux RB, Kizer JR, Howard BV, Cowan LD, Yeh J, Howard WJ, Wang W, Best L, Lee ET. Incidence and risk factors for stroke in American Indians: the Strong Heart Study. Circulation. 2008 Oct 07; 118(15):1577-84. PMID: 18809797; PMCID: PMC2754380.
    142. Kizer JR, Barzilay JI, Kuller LH, Gottdiener JS. Adiponectin and risk of coronary heart disease in older men and women. J Clin Endocrinol Metab. 2008 Sep; 93(9):3357-64. PMID: 18593765; PMCID: PMC2567853.
    143. Doufekias E, Segal AZ, Kizer JR. Cardiogenic and aortogenic brain embolism. J Am Coll Cardiol. 2008 Mar 18; 51(11):1049-59. PMID: 18342221.
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    144. Kizer JR. Patent foramen ovale and cryptogenic stroke. Am J Med. 2007 Dec; 120(12):e13; author reply e15. PMID: 18060903.
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    145. Fossum E, Gleim GW, Kjeldsen SE, Kizer JR, Julius S, Devereux RB, Brady WE, Hille DA, Lyle PA, Dahlöf B. The effect of baseline physical activity on cardiovascular outcomes and new-onset diabetes in patients treated for hypertension and left ventricular hypertrophy: the LIFE study. J Intern Med. 2007 Oct; 262(4):439-48. PMID: 17875180.
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    146. Pulte ED, Broekman MJ, Olson KE, Drosopoulos JH, Kizer JR, Islam N, Marcus AJ. CD39/NTPDase-1 activity and expression in normal leukocytes. Thromb Res. 2007; 121(3):309-17. PMID: 17555802; PMCID: PMC2255570.
    147. Roman MJ, Devereux RB, Kizer JR, Lee ET, Galloway JM, Ali T, Umans JG, Howard BV. Central pressure more strongly relates to vascular disease and outcome than does brachial pressure: the Strong Heart Study. Hypertension. 2007 Jul; 50(1):197-203. PMID: 17485598.
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    148. Mishra RK, Kizer JR, Palmieri V, Roman MJ, Galloway JM, Fabsitz RR, Lee ET, Best LG, Devereux RB. Utility of the myocardial performance index in a population with high prevalences of obesity, diabetes, and hypertension: the strong heart study. Echocardiography. 2007 Apr; 24(4):340-7. PMID: 17381641.
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    149. Karas MG, Francescone S, Segal AZ, Devereux RB, Roman MJ, Liu JE, Hahn RT, Kizer JR. Relation between mitral annular calcium and complex aortic atheroma in patients with cerebral ischemia referred for transesophageal echocardiography. Am J Cardiol. 2007 May 01; 99(9):1306-11. PMID: 17478163; PMCID: PMC1892237.
    150. Kjeldsen SE, Lyle PA, Kizer JR, Oparil S, Høieggen A, Os I. Fixed combination of losartan and hydrochlorothiazide and reduction of risk of stroke. Vasc Health Risk Manag. 2007; 3(3):299-305. PMID: 17703637; PMCID: PMC2293966.
    151. Kizer JR, Devereux RB. Regression of left ventricular hypertrophy: lodestar to stroke prevention in the treatment of hypertension? Am J Hypertens. 2006 May; 19(5):439-42. PMID: 16647610.
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    152. Dutta T, Karas MG, Segal AZ, Kizer JR. Yield of transesophageal echocardiography for nonbacterial thrombotic endocarditis and other cardiac sources of embolism in cancer patients with cerebral ischemia. Am J Cardiol. 2006 Mar 15; 97(6):894-8. PMID: 16516597.
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    153. Kizer JR, Bella JN, Palmieri V, Liu JE, Best LG, Lee ET, Roman MJ, Devereux RB. Left atrial diameter as an independent predictor of first clinical cardiovascular events in middle-aged and elderly adults: the Strong Heart Study (SHS). Am Heart J. 2006 Feb; 151(2):412-8. PMID: 16442908.
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    154. Kizer JR, Devereux RB. Clinical practice. Patent foramen ovale in young adults with unexplained stroke. N Engl J Med. 2005 Dec 01; 353(22):2361-72. PMID: 16319385.
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    155. Kizer JR, Wiebers DO, Whisnant JP, Galloway JM, Welty TK, Lee ET, Best LG, Resnick HE, Roman MJ, Devereux RB. Mitral annular calcification, aortic valve sclerosis, and incident stroke in adults free of clinical cardiovascular disease: the Strong Heart Study. Stroke. 2005 Dec; 36(12):2533-7. PMID: 16254219.
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    156. de Simone G, Devereux RB, Kizer JR, Chinali M, Bella JN, Oberman A, Kitzman DW, Hopkins PN, Rao DC, Arnett DK. Body composition and fat distribution influence systemic hemodynamics in the absence of obesity: the HyperGEN Study. Am J Clin Nutr. 2005 Apr; 81(4):757-61. PMID: 15817849.
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    157. Kjeldsen SE, Lyle PA, Kizer JR, Dahlöf B, Devereux RB, Julius S, Beevers G, de Faire U, Fyhrquist F, Ibsen H, Kristianson K, Lederballe-Pedersen O, Lindholm LH, Nieminen MS, Omvik P, Oparil S, Snapinn SM, Harris KE, Wedel H. The effects of losartan compared to atenolol on stroke in patients with isolated systolic hypertension and left ventricular hypertrophy. The LIFE study. J Clin Hypertens (Greenwich). 2005 Mar; 7(3):152-8. PMID: 15785156.
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    158. de Simone G, Kizer JR, Chinali M, Roman MJ, Bella JN, Best LG, Lee ET, Devereux RB. Normalization for body size and population-attributable risk of left ventricular hypertrophy: the Strong Heart Study. Am J Hypertens. 2005 Feb; 18(2 Pt 1):191-6. PMID: 15752946.
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    159. Kizer JR, Dahlöf B, Kjeldsen SE, Julius S, Beevers G, de Faire U, Fyhrquist F, Ibsen H, Kristianson K, Lederballe-Pedersen O, Lindholm LH, Nieminen MS, Omvik P, Oparil S, Wedel H, Wachtell K, Edelman JM, Snapinn SM, Harris KE, Devereux RB. Stroke reduction in hypertensive adults with cardiac hypertrophy randomized to losartan versus atenolol: the Losartan Intervention For Endpoint reduction in hypertension study. Hypertension. 2005 Jan; 45(1):46-52. PMID: 15583076.
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    160. Edelberg JM, Wong A, Holm JM, Xaymardan M, Duignan I, Chin A, Kizer JR, Cai D. Phage display identification of age-associated TNFalpha-mediated cardiac oxidative induction. Physiol Genomics. 2004 Aug 11; 18(3):255-60. PMID: 15187201.
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    161. Kizer JR, Arnett DK, Bella JN, Paranicas M, Rao DC, Province MA, Oberman A, Kitzman DW, Hopkins PN, Liu JE, Devereux RB. Differences in left ventricular structure between black and white hypertensive adults: the Hypertension Genetic Epidemiology Network study. Hypertension. 2004 Jun; 43(6):1182-8. PMID: 15123573.
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    162. Messé SR, Silverman IE, Kizer JR, Homma S, Zahn C, Gronseth G, Kasner SE. Practice parameter: recurrent stroke with patent foramen ovale and atrial septal aneurysm: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2004 Apr 13; 62(7):1042-50. PMID: 15078999.
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    163. Kizer JR, Zisman DA, Blumenthal NP, Kotloff RM, Kimmel SE, Strieter RM, Arcasoy SM, Ferrari VA, Hansen-Flaschen J. Association between pulmonary fibrosis and coronary artery disease. Arch Intern Med. 2004 Mar 08; 164(5):551-6. PMID: 15006833.
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    164. Kizer JR, Muttrej MR, Matthai WH, McConnell J, Nardone H, Sonel AF, Keane MG, Wilensky RL. Role of cardiac troponin T in the long-term risk stratification of patients undergoing percutaneous coronary intervention. Eur Heart J. 2003 Jul; 24(14):1314-22. PMID: 12871688.
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    165. Cai D, Xaymardan M, Holm JM, Zheng J, Kizer JR, Edelberg JM. Age-associated impairment in TNF-alpha cardioprotection from myocardial infarction. Am J Physiol Heart Circ Physiol. 2003 Aug; 285(2):H463-9. PMID: 12730063.
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    166. Kizer JR, Berlin JA, Laskey WK, Schwartz JS, Sauer WH, Krone RJ, Kimmel SE. Limitations of current risk-adjustment models in the era of coronary stenting. Am Heart J. 2003 Apr; 145(4):683-92. PMID: 12679766.
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    167. Samaha FF, Kimmel SE, Kizer JR, Goyal A, Wade M, Boden WE. Usefulness of the TIMI risk score in predicting both short- and long-term outcomes in the Veterans Affairs Non-Q-Wave Myocardial Infarction Strategies In-Hospital (VANQWISH) Trial. Am J Cardiol. 2002 Nov 01; 90(9):922-6. PMID: 12398955.
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    168. Kizer JR, Silvestry FE, Kimmel SE, Kasner SE, Wiegers SE, Erwin MB, Schwalm SA, Viswanathan MN, Pollard JR, Keane MG, Sutton MG. Racial differences in the prevalence of cardiac sources of embolism in subjects with unexplained stroke or transient ischemic attack evaluated by transesophageal echocardiography. Am J Cardiol. 2002 Aug 15; 90(4):395-400. PMID: 12161229.
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    169. Kizer JR, Kimmel SE. Epidemiologic review of the calcium channel blocker drugs. An up-to-date perspective on the proposed hazards. Arch Intern Med. 2001 May 14; 161(9):1145-58. PMID: 11343438.
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    170. Kizer JR, Gefter WB, deLemos AS, Scoll BJ, Wolfe ML, Mohler ER. Electron beam computed tomography for the quantification of aortic valvular calcification. J Heart Valve Dis. 2001 May; 10(3):361-6. PMID: 11380099.
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    171. Kizer JR, Koniaris LS, Edelman JD, St John Sutton MG. Pheochromocytoma crisis, cardiomyopathy, and hemodynamic collapse. Chest. 2000 Oct; 118(4):1221-3. PMID: 11035703.
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    172. Kizer JR, Kimmel SE. The calcium-channel blocker controversy: historical perspective and important lessons for future pharmacotherapies. An international society of pharmacoepidemiology 'hot topic'. Pharmacoepidemiol Drug Saf. 2000 Jan; 9(1):25-35. PMID: 19025799.
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    173. Kizer JR, Cannon CP, McCabe CH, Mueller HS, Schweiger MJ, Davis VG, Perritt R, Antman EM. Trends in the use of pharmacotherapies for acute myocardial infarction among physicians who design and/or implement randomized trials versus physicians in routine clinical practice: the MILIS-TIMI experience. Multicenter Investigation on Limitation of Infarct Size. Thrombolysis in Myocardial Infarction. Am Heart J. 1999 Jan; 137(1):79-92. PMID: 9878939.
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    174. Kizer JR, Bellah RD, Schnaufer L, Canning DA. Meconium hydrocele in a female newborn: an unusual cause of a labial mass. J Urol. 1995 Jan; 153(1):188-90. PMID: 7966770.
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