Mehrdad Arjomandi, MD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address4150 Clement Street, #3A-128
San Francisco CA 94121
Phone415-221-4810 ext. 24393
ORCID ORCID Icon0000-0002-0116-9217 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California, San DiegoBA06/1991Molecular Biology
    Stanford UniversityMD06/1996MD Program
    University of California, Los AngelesResidency06/1999Internal Medicine
    University of California, San FranciscoFellowship06/2003Pulmonary & Critical Care Medicine
    University of California, San FranciscoCertificate06/2003Advanced Training in Clinical Research
    Veterans Affairs Cooperative Study ProgramCertificate08/2009Clinical Trial Design Course
    University of California, San FranciscoCertificate05/2010Mentor Development Program
    The Jackson Laboratories (NIH/NHLBI)Certificate10/2010Genetic Approaches to Complex Heart, Lung and Blood Diseases
    University of California, San Francisco, CA2018Diversity, Equity, and Inclusion Champion Training
    Collapse Awards and Honors
    San Francisco VA Healthcare System2022SFVA Dept of Medicine HeRO Award

    Collapse Overview 
    Collapse Overview
    Dr. Arjomandi grew up in Ahvaz, a small city in Southwestern Iran, and moved to the United States in 1986 in the aftermath of Iranian revolution (1979), Iraq's invasion of Iran (1980-88), and his family displacement inside Iran (1980-83). When in California, he began his higher education at Los Angeles Pierce College before transferring to University of California San Diego in 1988, where he obtained a bachelor degree in molecular biology and completed a senior honors thesis in developmental biology in Dr. Richard Firtel’s lab. He then attended Stanford University School of Medicine in 1991, completing two predoctoral research fellowships in Dr. Etienne Emile Beaulieu’s lab at INSERM in Paris, France, and Dr. John Cooke’s vascular biology lab at Stanford. Dr. Arjomandi then completed a residency in internal medicine at UCLA (1996-99) and a fellowship in pulmonary and critical care at UCSF (2000-03). He completed three additional years of research fellowship funded by the American Lung Association and Chest Foundation before successfully competing for an NIH K23 award in 2006 and then joining the pulmonary and critical care faculty at UCSF and San Francisco General Hospital (SFGH). In 2008, he obtained a joint appointment at San Francisco VA Medical Center (SF VA).

    Currently, Dr. Arjomandi is Professor of Medicine in the Divisions of Pulmonary, Critical Care, Allergy, and Sleep Medicine and Occupational and Environmental Medicine at UCSF with a joint appointment at SF VA. He is Director of the UCSF Human Exposure Laboratory at SFGH, Director of Environmental Medicine Clinic at SF VA, Site Director for the SF VA Airborne Hazard Exposure Study Center of Excellence, an investigator at the UCSF Center for Tobacco Control Research and Education, and a member of the UCSF Helen Diller Family Comprehensive Cancer Center.

    Research Interests

    The lung is constantly exposed to various environmental pollutants, allergens, and toxins, which interact with airways and alveoli and result in inflammation, injury, and disease. My laboratory primary research interest has been centered on the paradigm that respiratory exposures to pollutants and toxicants contribute to development and progression of chronic lung diseases, and may further yield systemic effects well beyond lungs. Under this paradigm, my research activities have focused on understanding the physiologic and immunologic mechanisms via which environmental exposures contribute to chronic lung diseases and how knowledge of these mechanisms could be translated to ways to better define, prognosticate, and manage disease burden at both individual and societal levels.

    I have dedicated my efforts to (1) investigate the biology of airway immune cells using inhalational exposure to ozone in humans as a model of lung injury simulating exacerbation in chronic lung disease, and (2) characterize the early cardiopulmonary changes due to exposure to tobacco smoke and the pathophysiology and biology associated with those changes.
    Collapse Mentoring

    Collapse Research 
    Collapse Research Activities and Funding
    Occult Cardiovascular Disease with Chronic Exposure to Secondhand Tobacco Smoke
    Flight Attendant Medical Research Institute (FAMRI) SFGH FoundationJul 1, 2020 - Jun 30, 2025
    Role: PI
    Lung Macrophage Populations and Functions in COPD-Susceptible Smokers (Pre-COPD Study)
    Department of Defense W81XWH-20-1-0158Apr 1, 2020 - Mar 31, 2024
    Role: PI
    Characterization of Innate Immunity in Pollution-induced Exacerbation in Chronic Obstructive Pulmonary Disease (CO3PD Study)
    California TRDRP T29IR0715Apr 1, 2019 - Mar 31, 2024
    Role: PI

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications
    Collapse Academic Senate

    Collapse Featured Content 
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. 0891 Sleep Quality Among Post-9/11 Veterans with Exposure to Airborne Hazards. Sleep. 2024 Apr 20; 47(Supplement_1):a382-a383. Glick GD, Konikkara KJ, Sotolongo SA, Alexander AT, Diaz-Abad DM, So SJ, Arjomandi AM, Krefft KS, Osterholzer OJ, Richmond RB, Falvo FM. .
      View in: Publisher Site   Mentions:
    2. The Effect of Chronic Altitude Exposure on COPD Outcomes in the SPIROMICS Cohort. Am J Respir Crit Care Med. 2024 Mar 20. Suri R, Markovic D, Woo H, Arjomandi M, Barr RG, Bowler RP, Criner G, Curtis JL, Dransfield MT, Drummond MB, Fortis S, Han MK, Hoffman EA, Kaner RJ, Kaufman JD, Krishnan JA, Martinez FJ, Ohar J, Ortega VE, Paine Iii R, Soler X, Woodruff PG, Hansel NN, Cooper CB, Tashkin DP, Buhr RG, Barjaktarevic IZ. PMID: 38507607.
      View in: PubMed   Mentions:    Fields:    
    3. Effect of twice daily inhaled albuterol on cardiopulmonary exercise outcomes, dynamic hyperinflation, and symptoms in secondhand tobacco-exposed persons with preserved spirometry and air trapping: a randomized controlled trial. BMC Pulm Med. 2024 Jan 20; 24(1):44. Zeng S, Nishihama M, Weldemichael L, Lozier H, Gold WM, Arjomandi M. PMID: 38245665; PMCID: PMC10799390.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Response. Chest. 2024 01; 165(1):e25-e26. Seedahmed MI, Albirair MT, Whooley MA, Koth LL, Blanc PD, Arjomandi M. PMID: 38199743; PMCID: PMC10925540.
      View in: PubMed   Mentions:    Fields:    
    5. Effect of a single one-hour teaching session about environmental pollutants and climate change on the understanding and behavioral choices of adolescents: The BREATHE pilot randomized controlled trial. PLoS One. 2023; 18(11):e0291199. Abrham Y, Zeng S, Tenney R, Davidson C, Yao E, Kloth C, Dalton S, Arjomandi M. PMID: 38011223; PMCID: PMC10681291.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Lung volumes differentiate the predominance of emphysema versus airway disease phenotype in early COPD: an observational study of the COPDGene cohort. ERJ Open Res. 2023 Sep; 9(5). Zeng S, Luo G, Lynch DA, Bowler RP, Arjomandi M. PMID: 37727675; PMCID: PMC10505951.
      View in: PubMed   Mentions: 3  
    7. Longitudinal Follow-Up of Participants With Tobacco Exposure and Preserved Spirometry. JAMA. 2023 08 01; 330(5):442-453. McKleroy W, Shing T, Anderson WH, Arjomandi M, Awan HA, Barjaktarevic I, Barr RG, Bleecker ER, Boscardin J, Bowler RP, Buhr RG, Criner GJ, Comellas AP, Curtis JL, Dransfield M, Doerschuk CM, Dolezal BA, Drummond MB, Han MK, Hansel NN, Helton K, Hoffman EA, Kaner RJ, Kanner RE, Krishnan JA, Lazarus SC, Martinez FJ, Ohar J, Ortega VE, Paine R, Peters SP, Reinhardt JM, Rennard S, Smith BM, Tashkin DP, Couper D, Cooper CB, Woodruff PG. PMID: 37526720; PMCID: PMC10394572.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    8. Changes in Lung Volumes with Spirometric Disease Progression in COPD. Chronic Obstr Pulm Dis. 2023 Jul 26; 10(3):270-285. Arjomandi M, Zeng S, Chen J, Bhatt SP, Abtin F, Barjaktarevic I, Barr RG, Bleecker ER, Buhr RG, Criner GJ, Comellas AP, Couper DJ, Curtis JL, Dransfield MT, Fortis S, Han MK, Hansel NN, Hoffman EA, Hokanson JE, Kaner RJ, Kanner RE, Krishnan JA, Labaki WW, Lynch DA, Ortega VE, Peters SP, Woodruff PG, Cooper CB, Bowler RP, Paine R, Rennard SI, Tashkin DP, and the COPDGene and SPIROMICS Investigators. PMID: 37199719; PMCID: PMC10484496.
      View in: PubMed   Mentions: 3  
    9. Screening for Exposure to Beryllium Among US Veterans With a Diagnosis of Sarcoidosis, 2002-2020. Chest. 2023 11; 164(5):1253-1256. Seedahmed MI, Albirair MT, Whooley MA, Koth LL, Blanc PD, Arjomandi M. PMID: 37364853; PMCID: PMC10792292.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Epidemiology of Sarcoidosis in U.S. Veterans from 2003 to 2019. Ann Am Thorac Soc. 2023 06; 20(6):797-806. Seedahmed MI, Baugh AD, Albirair MT, Luo Y, Chen J, McCulloch CE, Whooley MA, Koth LL, Arjomandi M. PMID: 36724377; PMCID: PMC10257030.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    11. A MUC5B Gene Polymorphism, rs35705950-T, Confers Protective Effects Against COVID-19 Hospitalization but Not Severe Disease or Mortality. Am J Respir Crit Care Med. 2022 11 15; 206(10):1220-1229. Verma A, Minnier J, Wan ES, Huffman JE, Gao L, Joseph J, Ho YL, Wu WC, Cho K, Gorman BR, Rajeevan N, Pyarajan S, Garcon H, Meigs JB, Sun YV, Reaven PD, McGeary JE, Suzuki A, Gelernter J, Lynch JA, Petersen JM, Zekavat SM, Natarajan P, Dalal S, Jhala DN, Arjomandi M, Gatsby E, Lynch KE, Bonomo RA, Freiberg M, Pathak GA, Zhou JJ, Donskey CJ, Madduri RK, Wells QS, Huang RDL, Polimanti R, Chang KM, Liao KP, Tsao PS, Wilson PWF, Hung AM, O'Donnell CJ, Gaziano JM, Hauger RL, Iyengar SK, Luoh SW, Million Veteran Program COVID-19 Science Initiative. PMID: 35771531; PMCID: PMC9746845.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    12. Bronchodilator Responsiveness in Tobacco-Exposed People With or Without COPD. Chest. 2023 03; 163(3):502-514. Fortis S, Quibrera PM, Comellas AP, Bhatt SP, Tashkin DP, Hoffman EA, Criner GJ, Han MK, Barr RG, Arjomandi M, Dransfield MB, Peters SP, Dolezal BA, Kim V, Putcha N, Rennard SI, Paine R, Kanner RE, Curtis JL, Bowler RP, Martinez FJ, Hansel NN, Krishnan JA, Woodruff PG, Barjaktarevic IZ, Couper D, Anderson WH, Cooper CB, Subpopulations and Intermediate Outcome Measures in COPD Study Investigators. PMID: 36395858; PMCID: PMC9993341.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Consensus Statements on Deployment-Related Respiratory Disease, Inclusive of Constrictive Bronchiolitis: A Modified Delphi Study. Chest. 2023 03; 163(3):599-609. Falvo MJ, Sotolongo AM, Osterholzer JJ, Robertson MW, Kazerooni EA, Amorosa JK, Garshick E, Jones KD, Galvin JR, Kreiss K, Hines SE, Franks TJ, Miller RF, Rose CS, Arjomandi M, Krefft SD, Morris MJ, Polosukhin VV, Blanc PD, D'Armiento JM. PMID: 36343686; PMCID: PMC10154857.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. Bronchodilators in Tobacco-Exposed Persons with Symptoms and Preserved Lung Function. N Engl J Med. 2022 09 29; 387(13):1173-1184. Han MK, Ye W, Wang D, White E, Arjomandi M, Barjaktarevic IZ, Brown SA, Buhr RG, Comellas AP, Cooper CB, Criner GJ, Dransfield MT, Drescher F, Folz RJ, Hansel NN, Kalhan R, Kaner RJ, Kanner RE, Krishnan JA, Lazarus SC, Maddipati V, Martinez FJ, Mathews A, Meldrum C, McEvoy C, Nyunoya T, Rogers L, Stringer WW, Wendt CH, Wise RA, Wisniewski SR, Sciurba FC, Woodruff PG, RETHINC Study Group. PMID: 36066078; PMCID: PMC9741866.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    15. Reversible Airflow Obstruction Predicts Future Chronic Obstructive Pulmonary Disease Development in the SPIROMICS Cohort: An Observational Cohort Study. Am J Respir Crit Care Med. 2022 09 01; 206(5):554-562. Buhr RG, Barjaktarevic IZ, Quibrera PM, Bateman LA, Bleecker ER, Couper DJ, Curtis JL, Dolezal BA, Han MK, Hansel NN, Krishnan JA, Martinez FJ, McKleroy W, Paine R, Rennard SI, Tashkin DP, Woodruff PG, Kanner RE, Cooper CB, SPIROMICS Investigators. PMID: 35549640; PMCID: PMC9716898.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    16. Postdeployment Respiratory Health: The Roles of the Airborne Hazards and Open Burn Pit Registry and the Post-Deployment Cardiopulmonary Evaluation Network. Fed Pract. 2022 Aug; 39(8):337-343. Davis CW, Rabin AS, Jani N, Osterholzer JJ, Krefft S, Hines SE, Arjomandi M, Robertson MW, Sotolongo AM, Falvo MJ, Post-Deployment Cardiopulmonary Evaluation Network. PMID: 36425809; PMCID: PMC9652027.
      View in: PubMed   Mentions: 1  
    17. Lung Microbiota and Metabolites Collectively Associate with Clinical Outcomes in Milder Stage Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2022 08 15; 206(4):427-439. Madapoosi SS, Cruickshank-Quinn C, Opron K, Erb-Downward JR, Begley LA, Li G, Barjaktarevic I, Barr RG, Comellas AP, Couper DJ, Cooper CB, Freeman CM, Han MK, Kaner RJ, Labaki W, Martinez FJ, Ortega VE, Peters SP, Paine R, Woodruff P, Curtis JL, Huffnagle GB, Stringer KA, Bowler RP, Esther CR, Reisdorph N, Huang YJ, SPIROMICS Research Group. PMID: 35536732.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    18. NF-κB inhibitor alpha has a cross-variant role during SARS-CoV-2 infection in ACE2-overexpressing human airway organoids. bioRxiv. 2022 Aug 02. Simoneau CR, Chen PY, Xing GK, Khalid MM, Meyers NL, Hayashi JM, Taha TY, Leon KE, Ashuach T, Fontaine KA, Rodriguez L, Joehnk B, Walcott K, Vasudevan S, Fang X, Maishan M, Schultz S, Roose J, Matthay MA, Sil A, Arjomandi M, Yosef N, Ott M. PMID: 35982664; PMCID: PMC9387123.
      View in: PubMed   Mentions: 1  
    19. Association of Kidney Comorbidities and Acute Kidney Failure With Unfavorable Outcomes After COVID-19 in Individuals With the Sickle Cell Trait. JAMA Intern Med. 2022 08 01; 182(8):796-804. Verma A, Huffman JE, Gao L, Minnier J, Wu WC, Cho K, Ho YL, Gorman BR, Pyarajan S, Rajeevan N, Garcon H, Joseph J, McGeary JE, Suzuki A, Reaven PD, Wan ES, Lynch JA, Petersen JM, Meigs JB, Freiberg MS, Gatsby E, Lynch KE, Zekavat SM, Natarajan P, Dalal S, Jhala DN, Arjomandi M, Bonomo RA, Thompson TK, Pathak GA, Zhou JJ, Donskey CJ, Madduri RK, Wells QS, Gelernter J, Huang RDL, Polimanti R, Chang KM, Liao KP, Tsao PS, Sun YV, Wilson PWF, O'Donnell CJ, Hung AM, Gaziano JM, Hauger RL, Iyengar SK, Luoh SW, VA Million Veteran Program COVID-19 Science Initiative. PMID: 35759254; PMCID: PMC9237798.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    20. Elastin Degradation and Lung Function Deterioration with Remote Secondhand Tobacco Smoke Exposure in Never-smokers. Chronic Obstr Pulm Dis. 2022 Jul 29; 9(3):377-393. Mustra Rakic J, Zeng S, Rohdin-Bibby L, Van Blarigan EL, Liu X, Ma S, Kane JP, Redberg RF, Turino GM, Oestreicher Stock E, Arjomandi M. PMID: 35700534; PMCID: PMC9448014.
      View in: PubMed   Mentions: 1  
    21. Effect of ozone on allergic airway inflammation. J Allergy Clin Immunol Glob. 2022 Nov; 1(4):273-281. Arjomandi M, Wong H, Tenney R, Holland N, Balmes JR. PMID: 36643820; PMCID: PMC9838882.
      View in: PubMed   Mentions:
    22. Remote exposure to secondhand tobacco smoke is associated with lower exercise capacity through effects on oxygen pulse, a proxy of cardiac stroke volume. BMJ Open Respir Res. 2022 05; 9(1). Zeng S, Dunn M, Gold WM, Kizer JR, Arjomandi M. PMID: 35551073; PMCID: PMC9109127.
      View in: PubMed   Mentions: 1  Translation:HumansPHPublic Health
    23. Forced Expiratory Flow at 25%-75% Links COPD Physiology to Emphysema and Disease Severity in the SPIROMICS Cohort. Chronic Obstr Pulm Dis. 2022 Apr 29; 9(2):111-121. Ronish BE, Couper DJ, Barjaktarevic IZ, Cooper CB, Kanner RE, Pirozzi CS, Kim V, Wells JM, Han MK, Woodruff PG, Ortega VE, Peters SP, Hoffman EA, Buhr RG, Dolezal BA, Tashkin DP, Liou TG, Bateman LA, Schroeder JD, Martinez FJ, Barr RG, Hansel NN, Comellas AP, Rennard SI, Arjomandi M, Paine Iii R. PMID: 35114743; PMCID: PMC9166328.
      View in: PubMed   Mentions: 7  
    24. Performance of a Computational Phenotyping Algorithm for Sarcoidosis Using Diagnostic Codes in Electronic Medical Records: Case Validation Study From 2 Veterans Affairs Medical Centers. JMIR Form Res. 2022 Mar 02; 6(3):e31615. Seedahmed MI, Mogilnicka I, Zeng S, Luo G, Whooley MA, McCulloch CE, Koth L, Arjomandi M. PMID: 35081036; PMCID: PMC8928044.
      View in: PubMed   Mentions: 1  
    25. Automatically Explaining Machine Learning Predictions on Severe Chronic Obstructive Pulmonary Disease Exacerbations: Retrospective Cohort Study. JMIR Med Inform. 2022 Feb 25; 10(2):e33043. Zeng S, Arjomandi M, Luo G. PMID: 35212634; PMCID: PMC8917430.
      View in: PubMed   Mentions: 1  
    26. Genetic Loci Associated With COVID-19 Positivity and Hospitalization in White, Black, and Hispanic Veterans of the VA Million Veteran Program. Front Genet. 2021; 12:777076. Peloso GM, Tcheandjieu C, McGeary JE, Posner DC, Ho YL, Zhou JJ, Hilliard AT, Joseph J, O'Donnell CJ, Efird JT, Crawford DC, Wu WC, Arjomandi M, VA Million Veteran Program COVID-19 Science Initiative, Sun YV, Assimes TL, Huffman JE. PMID: 35222515; PMCID: PMC8864634.
      View in: PubMed   Mentions: 3  
    27. Developing a Machine Learning Model to Predict Severe Chronic Obstructive Pulmonary Disease Exacerbations: Retrospective Cohort Study. J Med Internet Res. 2022 01 06; 24(1):e28953. Zeng S, Arjomandi M, Tong Y, Liao ZC, Luo G. PMID: 34989686; PMCID: PMC8778560.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    28. Effects of short-term increases in personal and ambient pollutant concentrations on pulmonary and cardiovascular function: A panel study analysis of the Multicenter Ozone Study in oldEr subjects (MOSES 2). Environ Res. 2022 04 01; 205:112522. Frampton MW, Balmes JR, Bromberg PA, Arjomandi M, Hazucha MJ, Thurston SW, Alexis NE, Ganz P, Zareba W, Koutrakis P, Thevenet-Morrison K, Rich DQ. PMID: 34919956.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    29. Significance of FEV3/FEV6 in Recognition of Early Airway Disease in Smokers at Risk of Development of COPD: Analysis of the SPIROMICS Cohort. Chest. 2022 04; 161(4):949-959. Yee N, Markovic D, Buhr RG, Fortis S, Arjomandi M, Couper D, Anderson WH, Paine R, Woodruff PG, Han MK, Martinez FJ, Barr RG, Wells JM, Ortega VE, Hoffman EA, Kim V, Drummond MB, Bowler RP, Curtis JL, Cooper CB, Tashkin DP, Barjaktarevic IZ. PMID: 34767825; PMCID: PMC9005864.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    30. Actigraphy informs distinct patient-centered outcomes in Pre-COPD. Respir Med. 2021 10; 187:106543. Chen J, Weldemichael L, Zeng S, Giang B, Geerts J, Ching WC, Nishihama M, Gold WM, Arjomandi M. PMID: 34496341.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    31. Lung immune tone via gut-lung axis: gut-derived LPS and short-chain fatty acids' immunometabolic regulation of lung IL-1β, FFAR2, and FFAR3 expression. Am J Physiol Lung Cell Mol Physiol. 2021 07 01; 321(1):L65-L78. Liu Q, Tian X, Maruyama D, Arjomandi M, Prakash A. PMID: 33851870; PMCID: PMC8321849.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
    32. Ratio of FEV1/Slow Vital Capacity of < 0.7 Is Associated With Clinical, Functional, and Radiologic Features of Obstructive Lung Disease in Smokers With Preserved Lung Function. Chest. 2021 07; 160(1):94-103. Fortis S, Comellas AP, Bhatt SP, Hoffman EA, Han MK, Bhakta NR, Paine R, Ronish B, Kanner RE, Dransfield M, Hoesterey D, Buhr RG, Barr RG, Dolezal B, Ortega VE, Drummond MB, Arjomandi M, Kaner RJ, Kim V, Curtis JL, Bowler RP, Martinez F, Labaki WW, Cooper CB, O'Neal WK, Criner G, Hansel NN, Krishnan JA, Woodruff P, Couper D, Tashkin D, Barjaktarevic I. PMID: 33539837; PMCID: PMC8295909.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    33. Lower PDL1, PDL2, and AXL Expression on Lung Myeloid Cells Suggests Inflammatory Bias in Smoking and Chronic Obstructive Pulmonary Disease. Am J Respir Cell Mol Biol. 2020 12; 63(6):780-793. Vasudevan S, Vásquez JJ, Chen W, Aguilar-Rodriguez B, Niemi EC, Zeng S, Tamaki W, Nakamura MC, Arjomandi M. PMID: 32915645; PMCID: PMC7790144.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    34. Do Ambient Ozone or Other Pollutants Modify Effects of Controlled Ozone Exposure on Pulmonary Function? Ann Am Thorac Soc. 2020 05; 17(5):563-572. Rich DQ, Thurston SW, Balmes JR, Bromberg PA, Arjomandi M, Hazucha MJ, Alexis NE, Ganz P, Zareba W, Thevenet-Morrison K, Koutrakis P, Frampton MW. PMID: 32125874.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    35. Military Burn Pits. Am J Respir Crit Care Med. 2020 04 01; 201(7):P13-P14. Sotolongo A, Falvo M, Santos S, Johnson I, Arjomandi M, Hines S, Krefft S, Osterholzer J. PMID: 32233853.
      View in: PubMed   Mentions: 2     Fields:    
    36. Multicenter Ozone Study in oldEr Subjects (MOSES): Part 2. Effects of Personal and Ambient Concentrations of Ozone and Other Pollutants on Cardiovascular and Pulmonary Function. Res Rep Health Eff Inst. 2020 Mar; (192, Pt 2):1-90. Rich DQ, Frampton MW, Balmes JR, Bromberg PA, Arjomandi M, Hazucha MJ, Thurston SW, Alexis NE, Ganz P, Zareba W, Koutrakis P, Thevenet-Morrison K. PMID: 32239870; PMCID: PMC7325421.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    37. Laboratory-based Intermountain Validated Exacerbation (LIVE) Score stability in patients with chronic obstructive pulmonary disease. BMJ Open Respir Res. 2020 02; 7(1). Blagev DP, Collingridge DS, Rea S, Carey KA, Mularski RA, Zeng S, Arjomandi M, Press VG. PMID: 32060034; PMCID: PMC7047500.
      View in: PubMed   Mentions: Translation:Humans
    38. Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis. Int J Chron Obstruct Pulmon Dis. 2019; 14:2927-2938. Barjaktarevic IZ, Buhr RG, Wang X, Hu S, Couper D, Anderson W, Kanner RE, Paine Iii R, Bhatt SP, Bhakta NR, Arjomandi M, Kaner RJ, Pirozzi CS, Curtis JL, O'Neal WK, Woodruff PG, Han MK, Martinez FJ, Hansel N, Wells JM, Ortega VE, Hoffman EA, Doerschuk CM, Kim V, Dransfield MT, Drummond MB, Bowler R, Criner G, Christenson SA, Ronish B, Peters SP, Krishnan JA, Tashkin DP, Cooper CB, NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS). PMID: 31908441; PMCID: PMC6930016.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    39. Radiographic lung volumes predict progression to COPD in smokers with preserved spirometry in SPIROMICS. Eur Respir J. 2019 10; 54(4). Arjomandi M, Zeng S, Barjaktarevic I, Barr RG, Bleecker ER, Bowler RP, Buhr RG, Criner GJ, Comellas AP, Cooper CB, Couper DJ, Curtis JL, Dransfield MT, Han MK, Hansel NN, Hoffman EA, Kaner RJ, Kanner RE, Krishnan JA, Paine R, Peters SP, Rennard SI, Woodruff PG, SPIROMICS Investigators. PMID: 31439683; PMCID: PMC7089627.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    40. Ozone effects on blood biomarkers of systemic inflammation, oxidative stress, endothelial function, and thrombosis: The Multicenter Ozone Study in oldEr Subjects (MOSES). PLoS One. 2019; 14(9):e0222601. Balmes JR, Arjomandi M, Bromberg PA, Costantini MG, Dagincourt N, Hazucha MJ, Hollenbeck-Pringle D, Rich DQ, Stark P, Frampton MW. PMID: 31553765; PMCID: PMC6760801.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansPHPublic Health
    41. Back to the Box: Using Lung Volumes to Predict Susceptibility to Develop Chronic Obstructive Pulmonary Disease among Smokers. Ann Am Thorac Soc. 2018 Dec; 15(Supplement_4):S286-S287. Zeng S, Tham A, Bos B, Jin J, Arjomandi M. PMID: 30759017.
      View in: PubMed   Mentions:
    42. Inflammatory Phenotypes Associated with Chronic Obstructive Pulmonary Disease Increase Susceptibility to Exacerbation. Lessons from Single Cell Analysis of Lung Macrophages. Ann Am Thorac Soc. 2018 Dec; 15(Supplement_4):S289. Vasudevan S, Vasquez J, Chen W, Zeng S, Arjomandi M. PMID: 30759013.
      View in: PubMed   Mentions:
    43. Analytical validation of a novel multi-analyte plasma test for lung nodule characterization. Biomed Res Rev. 2018 Dec; 2(3). Trivedi NN, Brown JK, Rubenstein T, Rostykus AD, Fish AL, Yu H, Carbonell L, Juang A, Kamer S, Patel B, Sidhu M, Vuong D, Wang S, Beggs M, Wu AH, Arjomandi M. PMID: 32923944; PMCID: PMC7486005.
      View in: PubMed   Mentions: 2  
    44. Risk assessment for indeterminate pulmonary nodules using a novel, plasma-protein based biomarker assay. Biomed Res Clin Pract. 2018 Dec; 3(4). Trivedi NN, Arjomandi M, Brown JK, Rubenstein T, Rostykus AD, Esposito S, Axler E, Beggs M, Yu H, Carbonell L, Juang A, Kamer S, Patel B, Wang S, Fish AL, Haddad Z, Wu AH. PMID: 32913898; PMCID: PMC7480946.
      View in: PubMed   Mentions: 8  
    45. MA23.03 Risk Assessment for Indeterminate Pulmonary Nodules Using a Novel, Plasma-Protein Based Biomarker Assay. Journal of Thoracic Oncology. 2018 Oct 1; 13(10):s439. Fish FA, Vachani VA, Beggs BM, Carbonell CL, Haddad HZ, Juang JA, Kamer KS, Patel PB, Yu YH, Wu WA, Massion MP, Arjomandi AM, Brown BJ, Trivedi TN, Rubenstein RT. .
      View in: Publisher Site   Mentions:
    46. E-cigarettes versus nicotine patches for perioperative smoking cessation: a pilot randomized trial. PeerJ. 2018; 6:e5609. Lee SM, Tenney R, Wallace AW, Arjomandi M. PMID: 30280019; PMCID: PMC6166615.
      View in: PubMed   Mentions: 18     Fields:    
    47. Lung volume indices predict morbidity in smokers with preserved spirometry. Thorax. 2019 02; 74(2):114-124. Zeng S, Tham A, Bos B, Jin J, Giang B, Arjomandi M. PMID: 30030304; PMCID: PMC7476802.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    48. Cardiovascular function and ozone exposure: The Multicenter Ozone Study in oldEr Subjects (MOSES). Environ Int. 2018 10; 119:193-202. Rich DQ, Balmes JR, Frampton MW, Zareba W, Stark P, Arjomandi M, Hazucha MJ, Costantini MG, Ganz P, Hollenbeck-Pringle D, Dagincourt N, Bromberg PA. PMID: 29980042.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansPHPublic Health
    49. Marijuana Use, Respiratory Symptoms, and Pulmonary Function: A Systematic Review and Meta-analysis. Ann Intern Med. 2018 07 17; 169(2):106-115. Ghasemiesfe M, Ravi D, Vali M, Korenstein D, Arjomandi M, Frank J, Austin PC, Keyhani S. PMID: 29971337; PMCID: PMC6231497.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    50. Stability of Frequency of Severe Chronic Obstructive Pulmonary Disease Exacerbations and Health Care Utilization in Clinical Populations. Chronic Obstr Pulm Dis. 2018 Jun 20; 5(3):208-220. Blagev DP, Collingridge DS, Rea S, Press VG, Churpek MM, Carey K, Mularski RA, Zeng S, Arjomandi M. PMID: 30584584; PMCID: PMC6296787.
      View in: PubMed   Mentions: 6  
    51. The Laboratory-Based Intermountain Validated Exacerbation (LIVE) Score Identifies Chronic Obstructive Pulmonary Disease Patients at High Mortality Risk. Front Med (Lausanne). 2018; 5:173. Blagev DP, Collingridge DS, Rea S, Horne BD, Press VG, Churpek MM, Carey KA, Mularski RA, Zeng S, Arjomandi M. PMID: 29942803; PMCID: PMC6004514.
      View in: PubMed   Mentions: 4  
    52. Respiratory Responses to Ozone Exposure. MOSES (The Multicenter Ozone Study in Older Subjects). Am J Respir Crit Care Med. 2018 05 15; 197(10):1319-1327. Arjomandi M, Balmes JR, Frampton MW, Bromberg P, Rich DQ, Stark P, Alexis NE, Costantini M, Hollenbeck-Pringle D, Dagincourt N, Hazucha MJ. PMID: 29232153.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansPHPublic Health
    53. Lung volumes identify an at-risk group in persons with prolonged secondhand tobacco smoke exposure but without overt airflow obstruction. BMJ Open Respir Res. 2018; 5(1):e000284. Arjomandi M, Zeng S, Geerts J, Stiner RK, Bos B, van Koeverden I, Keene J, Elicker B, Blanc PD, Gold WM. PMID: 29755755; PMCID: PMC5942438.
      View in: PubMed   Mentions: 6  
    54. Increasing the Resolution of Chronic Obstructive Pulmonary Disease Definition. Lessons from a Cohort with Remote but Extensive Exposure to Secondhand Tobacco Smoke. Ann Am Thorac Soc. 2018 Apr; 15(Supplement_2):S122-S123. Arjomandi M, Zeng S, Blanc PD, Gold WM. PMID: 29676628.
      View in: PubMed   Mentions:
    55. Diagnosing Chronic Obstructive Pulmonary Disease Among Afghanistan and Iraq Veterans: Veterans Affair's Concordance With Clinical Guidelines for Spirometry Administration. Mil Med. 2017 09; 182(9):e1993-e2000. Schneiderman AI, Dougherty DD, Fonseca VP, Wolters CL, Bossarte RM, Arjomandi M. PMID: 28885968; PMCID: PMC5817986.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    56. Multicenter Ozone Study in oldEr Subjects (MOSES): Part 1. Effects of Exposure to Low Concentrations of Ozone on Respiratory and Cardiovascular Outcomes. Res Rep Health Eff Inst. 2017 06; (192, Pt 1):1-107. Frampton MW, Balmes JR, Bromberg PA, Stark P, Arjomandi M, Hazucha MJ, Rich DQ, Hollenbeck-Pringle D, Dagincourt N, Alexis N, Ganz P, Zareba W, Costantini MG. PMID: 31898880; PMCID: PMC7266375.
      View in: PubMed   Mentions: 6     Fields:    Translation:CTClinical Trials
    57. Modeling vascular inflammation and atherogenicity after inhalation of ambient levels of ozone: exploratory lessons from transcriptomics. Inhal Toxicol. 2017 02; 29(3):96-105. Tham A, Lullo D, Dalton S, Zeng S, van Koeverden I, Arjomandi M. PMID: 28412860; PMCID: PMC7456636.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    58. Asthma-COPD Overlap Syndrome- an Underdiagnosed Phenotype in Heavy Smokers. Journal of Allergy and Clinical Immunology. 2016 Feb 1; 137(2):ab102. Guenechea-Sola GM, Dalton DS, Geerts GJ, Zeng ZS, Arjomandi AM. .
      View in: Publisher Site   Mentions:
    59. Inflammatory and repair pathways induced in human bronchoalveolar lavage cells with ozone inhalation. PLoS One. 2015; 10(6):e0127283. Leroy P, Tham A, Wong H, Tenney R, Chen C, Stiner R, Balmes JR, Paquet AC, Arjomandi M. PMID: 26035830; PMCID: PMC4452717.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsCTClinical Trials
    60. Exposure to medium and high ambient levels of ozone causes adverse systemic inflammatory and cardiac autonomic effects. Am J Physiol Heart Circ Physiol. 2015 Jun 15; 308(12):H1499-509. Arjomandi M, Wong H, Donde A, Frelinger J, Dalton S, Ching W, Power K, Balmes JR. PMID: 25862833; PMCID: PMC4469877.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansPHPublic Health
    61. Ozone inhalation leads to a dose-dependent increase of cytogenetic damage in human lymphocytes. Environ Mol Mutagen. 2015 May; 56(4):378-87. Holland N, Davé V, Venkat S, Wong H, Donde A, Balmes JR, Arjomandi M. PMID: 25451016; PMCID: PMC4406783.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsPHPublic Health
    62. IQGAP1-dependent scaffold suppresses RhoA and inhibits airway smooth muscle contraction. J Clin Invest. 2014 Nov; 124(11):4895-8. Bhattacharya M, Sundaram A, Kudo M, Farmer J, Ganesan P, Khalifeh-Soltani A, Arjomandi M, Atabai K, Huang X, Sheppard D. PMID: 25271629; PMCID: PMC4347230.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    63. Secondhand Tobacco Smoke and COPD Risk in Smokers: A COPDGene Study Cohort Subgroup Analysis. COPD. 2015 04; 12(2):182-9. van Koeverden I, Blanc PD, Bowler RP, Arjomandi M. PMID: 24983136; PMCID: PMC4820340.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    64. Hidden Costs of Climate Change: Contribution of Ozone to Human Diseases. Proceedings of the American Association for the Advancement of Science. Proceedings of the U.S.-Iran Symposium on Air Pollution in Megacities. 2013. View Publication.
    65. Mfge8 suppresses airway hyperresponsiveness in asthma by regulating smooth muscle contraction. Proc Natl Acad Sci U S A. 2013 Jan 08; 110(2):660-5. Kudo M, Khalifeh Soltani SM, Sakuma SA, McKleroy W, Lee TH, Woodruff PG, Lee JW, Huang K, Chen C, Arjomandi M, Huang X, Atabai K. PMID: 23269839; PMCID: PMC3545777.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
    66. Oxidative Injury Due to Inhalation of Ozone Causes Dose-Dependent Cytogenetic Damage in Peripheral Blood Lymphocytes. Annals of the American Thoracic Society. 2012 May 1; 9(2):81-82. Arjomandi AM, Venkat VS, Wong WH, Donde DA, Balmes BJ, Holland HN. .
      View in: Publisher Site   Mentions:
    67. Reduced exercise tolerance and pulmonary capillary recruitment with remote secondhand smoke exposure. PLoS One. 2012; 7(4):e34393. Arjomandi M, Haight T, Sadeghi N, Redberg R, Gold WM. PMID: 22493689; PMCID: PMC3321018.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    68. Effects of exercise on systemic inflammatory, coagulatory, and cardiac autonomic parameters in an inhalational exposure study. J Occup Environ Med. 2012 Apr; 54(4):466-70. Donde A, Wong H, Frelinger J, Power K, Balmes JR, Arjomandi M. PMID: 22418276; PMCID: PMC3323713.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    69. Polymorphism in Osteopontin Gene (SPP1) Is Associated with Asthma and Related Phenotypes in a Puerto Rican Population. Pediatr Allergy Immunol Pulmonol. 2011 Dec; 24(4):207-214. Arjomandi M, Galanter JM, Choudhry S, Eng C, Hu D, Beckman K, Chapela R, Rodríguez-Santana JR, Rodríguez-Cintrón W, Ford J, Avila PC, Burchard EG. PMID: 22276228; PMCID: PMC3255512.
      View in: PubMed   Mentions: 10     Fields:    
    70. Secreted osteopontin is highly polymerized in human airways and fragmented in asthmatic airway secretions. PLoS One. 2011; 6(10):e25678. Arjomandi M, Frelinger J, Donde A, Wong H, Yellamilli A, Raymond W. PMID: 22031818; PMCID: PMC3198733.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    71. PAI-1 is an essential component of the pulmonary host response during Pseudomonas aeruginosa pneumonia in mice. Thorax. 2011 Sep; 66(9):788-96. Goolaerts A, Lafargue M, Song Y, Miyazawa B, Arjomandi M, Carlès M, Roux J, Howard M, Parks DA, Iles KE, Pittet JF. PMID: 21768189; PMCID: PMC3282176.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    72. Low prevalence of chronic beryllium disease among workers at a nuclear weapons research and development facility. J Occup Environ Med. 2010 Jun; 52(6):647-52. Arjomandi M, Seward J, Gotway MB, Nishimura S, Fulton GP, Thundiyil J, King TE, Harber P, Balmes JR. PMID: 20523233; PMCID: PMC3313491.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    73. Pulmonary function abnormalities in never-smoking flight attendants exposed to secondhand tobacco smoke in the aircraft cabin. J Occup Environ Med. 2009 Jun; 51(6):639-46. Arjomandi M, Haight T, Redberg R, Gold WM. PMID: 19448573; PMCID: PMC2722845.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansPHPublic Health
    74. Is there an association between lifetime cumulative exposure and acute pulmonary responses to ozone? J Occup Environ Med. 2008 Mar; 50(3):341-9. Arjomandi M, Tager IB, Bastaki M, Chen C, Holland N, Balmes JR. PMID: 18332784; PMCID: PMC3321313.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    75. Effects of chronic and acute ozone exposure on lipid peroxidation and antioxidant capacity in healthy young adults. Environ Health Perspect. 2007 Dec; 115(12):1732-7. Chen C, Arjomandi M, Balmes J, Tager I, Holland N. PMID: 18087591; PMCID: PMC2137098.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCellsPHPublic Health
    76. Effects of antioxidant enzyme polymorphisms on ozone-induced lung function changes. Eur Respir J. 2007 Oct; 30(4):677-83. Chen C, Arjomandi M, Tager IB, Holland N, Balmes JR. PMID: 17652311; PMCID: PMC3282174.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    77. Cytogenetic damage in buccal epithelia and peripheral lymphocytes of young healthy individuals exposed to ozone. Mutagenesis. 2006 Mar; 21(2):131-7. Chen C, Arjomandi M, Qin H, Balmes J, Tager I, Holland N. PMID: 16513656.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansPHPublic Health
    78. Effects of nitrogen dioxide on allergic airway responses in subjects with asthma. J Occup Environ Med. 2005 Dec; 47(12):1250-9. Witten A, Solomon C, Abbritti E, Arjomandi M, Zhai W, Kleinman M, Balmes J. PMID: 16340706.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    79. Sputum induction and bronchoscopy for assessment of ozone-induced airway inflammation in asthma. Chest. 2005 Jul; 128(1):416-23. Arjomandi M, Schmidlin I, Girling P, Boylen K, Ferrando R, Balmes J. PMID: 16002965.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    80. Repeated exposure to ozone increases alveolar macrophage recruitment into asthmatic airways. Am J Respir Crit Care Med. 2005 Aug 15; 172(4):427-32. Arjomandi M, Witten A, Abbritti E, Reintjes K, Schmidlin I, Zhai W, Solomon C, Balmes J. PMID: 15937293; PMCID: PMC2718526.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    81. Arginine restores nitric oxide activity and inhibits monocyte accumulation after vascular injury in hypercholesterolemic rabbits. J Am Coll Cardiol. 1996 Nov 15; 28(6):1573-9. Wang BY, Candipan RC, Arjomandi M, Hsiun PT, Tsao PS, Cooke JP. PMID: 8917274.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    82. Effects of immunosuppressants FK506 and rapamycin on the heterooligomeric form of the progesterone receptor. J Steroid Biochem Mol Biol. 1994 Jan; 48(1):101-10. Renoir JM, Le Bihan S, Mercier-Bodard C, Gold A, Arjomandi M, Radanyi C, Baulieu EE. PMID: 7510997.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
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