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Peter Ganz

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentMedicine
Address1001 Potrero Ave, SFGH 5
San Francisco CA 94110
Phone415-206-3024
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    Collapse Biography 
    Collapse Education and Training
    Harvard Medical School, Boston, MAMD06/1976Medicine
    Massachusetts General Hospital, Boston, MA06/1979Medical Residency
    Brigham and Women's Hospital, Boston, MA06/1982Cardiology Fellowship

    Collapse Overview 
    Collapse Overview
    Dr. Ganz is the Chief of Cardiology and the Co-Director of the Center of Excellence in Vascular Research at the Zuckerberg San Francisco General Hospital. He is also the Maurice Eliaser Distinguished Professor of Medicine at the University of California, San Francisco. Dr. Ganz has been a pioneer and a leader in translational and clinical cardiovascular research. His laboratory first published on vascular endothelial function in the state of health and on endothelial dysfunction in atherosclerosis in humans (N Engl J Med 1986; 315:1046-1051). He has been a leader in the field of human endothelial biology ever since. Currently, Dr. Ganz is making important discoveries in another field - the proteomics of cardiovascular diseases - using modified aptamers as binding reagents to quantify proteins in blood (JAMA 2016;315:2532-2541) and in other matrixes (e.g. urine). Dr. Ganz has authored nearly 250 peer-reviewed articles, many widely cited and published in the top tier medical journals. He has served on steering committees of numerous clinical trials. Many trainees who worked in Dr. Ganz’s laboratory have gone onto key leadership positions in academic medicine nationally and internationally. Dr. Ganz received his M.D. from Harvard Medical School, completed his residency at the Massachusetts General Hospital and cardiovascular fellowship at the Brigham and Women’s Hospital. He spent 25 years directing cardiovascular research in the Cardiac Catheterization Laboratories at the Brigham and Women’s Hospital and Harvard Medical School, prior to arriving to the University of California, San Francisco in 2008.


    Collapse Research 
    Collapse Research Activities and Funding
    Protein Biomarkers for CVD Prediction in HIV-Infected and Uninfected Veterans
    NIH/NHLBI R01HL129856Sep 1, 2016 - Jun 30, 2020
    Role: Co-Principal Investigator
    Identifying Modifiable Biomarkers/Mediators for Cardiovascular Disease in Chronic Kidney Disease
    NIH/NIDDK U01DK108809Aug 19, 2016 - Jul 31, 2021
    Role: Principal Investigator
    Comprehensive Evaluation of Aging-Related Clinical Outcomes and Geroproteins
    NIH/NIA R01AG052964Jun 1, 2016 - May 31, 2021
    Role: Co-Principal Investigator
    Improved Models to Inform Tobacco Product Regulation
    NIH/NCI P50CA180890Sep 19, 2013 - Aug 31, 2018
    Role: Co-Investigator
    CRITICAL TRANSITIONS IN ATHEROGENESIS
    NIH P50HL056985Apr 23, 1997 - Mar 31, 2008
    Role: Co-Investigator
    SEX HORMONES AND VASCULAR PROTECTION IN WOMEN
    NIH/NHLBI R01HL050890Jul 1, 1995 - Jun 30, 2000
    Role: Principal Investigator
    Arterial Dysfunction: Basic and Clinical Mechanisms
    NIH P01HL048743Sep 30, 1992 - Mar 31, 2015
    Role: Co-Investigator
    ENDOTHELIAL DYSFUNCTION IN CORONARY ATHEROSCLEROSIS
    NIH/NHLBI K04HL002566Jan 1, 1991 - Dec 31, 1995
    Role: Principal Investigator
    CHOLINERGIC MECHANISMS IN CULTURED VASCULAR CELLS
    NIH/NHLBI K08HL001725Jul 1, 1985 - Jun 30, 1987
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Global Health

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Ganz P, Amarenco P, Goldstein LB, Sillesen H, Bao W, Preston GM, Welch KMA. Association of Osteopontin, Neopterin, and Myeloperoxidase With Stroke Risk in Patients With Prior Stroke or Transient Ischemic Attacks: Results of an Analysis of 13 Biomarkers From the Stroke Prevention by Aggressive Reduction in Cholesterol Levels Trial. Stroke. 2017 12; 48(12):3223-3231. PMID: 29114094.
      View in: PubMed
    2. Williams SA, Murthy AC, DeLisle RK, Hyde C, Malarstig A, Ostroff R, Weiss SJ, Segal MR, Ganz P. Improving Assessment of Drug Safety Through Proteomics: Early Detection and Mechanistic Characterization of the Unforeseen Harmful Effects of Torcetrapib. Circulation. 2018 Mar 06; 137(10):999-1010. PMID: 28974520.
      View in: PubMed
    3. Guajardo I, Ayer A, Johnson AD, Ganz P, Mills C, Donovan C, Scherzer R, Shah SJ, Peralta CA, Dubin RF. Sex differences in vascular dysfunction and cardiovascular outcomes: The cardiac, endothelial function, and arterial stiffness in ESRD (CERES) study. Hemodial Int. 2018 Jan; 22(1):93-102. PMID: 28272770.
      View in: PubMed
    4. Tawakol A, Ishai A, Li D, Takx RA, Hur S, Kaiser Y, Pampaloni M, Rupert A, Hsu D, Sereti I, Fromentin R, Chomont N, Ganz P, Deeks SG, Hsue PY. Association of Arterial and Lymph Node Inflammation With Distinct Inflammatory Pathways in Human Immunodeficiency Virus Infection. JAMA Cardiol. 2017 Feb 01; 2(2):163-171. PMID: 27926762.
      View in: PubMed
    5. Huang AJ, Ganz P, Grady D, Cummings SR. In Reply. Menopause. 2017 Jan; 24(1):120. PMID: 28002350.
      View in: PubMed
    6. Sinha A, Ma Y, Scherzer R, Hur S, Li D, Ganz P, Deeks SG, Hsue PY. Role of T-Cell Dysfunction, Inflammation, and Coagulation in Microvascular Disease in HIV. J Am Heart Assoc. 2016 Dec 20; 5(12). PMID: 27998918.
      View in: PubMed
    7. Grubbs V, Garcia F, Jue BL, Vittinghoff E, Ryder M, Lovett D, Carrillo J, Offenbacher S, Ganz P, Bibbins-Domingo K, Powe NR. The Kidney and Periodontal Disease (KAPD) study: A pilot randomized controlled trial testing the effect of non-surgical periodontal therapy on chronic kidney disease. Contemp Clin Trials. 2017 02; 53:143-150. PMID: 28011387.
      View in: PubMed
    8. Huang AJ, Ganz P, Grady D, Cummings SR. Letters to the Editor. Menopause. 2016 Dec 05. PMID: 27922942.
      View in: PubMed
    9. Dubin RF, Guajardo I, Ayer A, Mills C, Donovan C, Beussink L, Scherzer R, Ganz P, Shah SJ. Associations of Macro- and Microvascular Endothelial Dysfunction With Subclinical Ventricular Dysfunction in End-Stage Renal Disease. Hypertension. 2016 10; 68(4):913-20. PMID: 27550915; PMCID: PMC5016254 [Available on 10/01/17].
    10. Ganz P, Heidecker B, Hveem K, Jonasson C, Kato S, Segal MR, Sterling DG, Williams SA. Development and Validation of a Protein-Based Risk Score for Cardiovascular Outcomes Among Patients With Stable Coronary Heart Disease. JAMA. 2016 Jun 21; 315(23):2532-41. PMID: 27327800.
      View in: PubMed
    11. Kohli P, Ganz P, Ma Y, Scherzer R, Hur S, Weigel B, Grunfeld C, Deeks S, Wasserman S, Scott R, Hsue PY. HIV and Hepatitis C-Coinfected Patients Have Lower Low-Density Lipoprotein Cholesterol Despite Higher Proprotein Convertase Subtilisin Kexin 9 (PCSK9): An Apparent "PCSK9-Lipid Paradox". J Am Heart Assoc. 2016 Apr 29; 5(5). PMID: 27130349; PMCID: PMC4889164.
    12. Walker RG, Poggioli T, Katsimpardi L, Buchanan SM, Oh J, Wattrus S, Heidecker B, Fong YW, Rubin LL, Ganz P, Thompson TB, Wagers AJ, Lee RT. Biochemistry and Biology of GDF11 and Myostatin: Similarities, Differences, and Questions for Future Investigation. Circ Res. 2016 Apr 01; 118(7):1125-41; discussion 1142. PMID: 27034275; PMCID: PMC4818972 [Available on 04/01/17].
    13. Huang AJ, Cummings SR, Schembri M, Vittinghoff E, Ganz P, Grady D. Continuous transdermal nitroglycerin therapy for menopausal hot flashes: a single-arm, dose-escalation trial. Menopause. 2016 Mar; 23(3):330-4. PMID: 26263283; PMCID: PMC4746109 [Available on 03/01/17].
    14. Parikh RV, Ma Y, Scherzer R, Heringer AS, Macgregor JS, Martin JN, Deeks SG, Ganz P, Hsue PY. Endothelin-1 Predicts Hemodynamically Assessed Pulmonary Arterial Hypertension in HIV Infection. PLoS One. 2016; 11(1):e0146355. PMID: 26752193; PMCID: PMC4709102.
    15. Spencer RM, Heidecker B, Ganz P. Behavioral Cardiovascular Risk Factors - Effect of Physical Activity and Cardiorespiratory Fitness on Cardiovascular Outcomes. Circ J. 2016; 80(1):34-43. PMID: 26673004.
      View in: PubMed
    16. Park M, Kulkarni A, Beatty A, Ganz P, Regan M, Vittinghoff E, Whooley M. Soluble endothelial cell selective adhesion molecule and cardiovascular outcomes in patients with stable coronary disease: A report from the Heart and Soul Study. Atherosclerosis. 2015 Dec; 243(2):546-52. PMID: 26523992.
      View in: PubMed
    17. Olson KA, Beatty AL, Heidecker B, Regan MC, Brody EN, Foreman T, Kato S, Mehler RE, Singer BS, Hveem K, Dalen H, Sterling DG, Lawn RM, Schiller NB, Williams SA, Whooley MA, Ganz P. Association of growth differentiation factor 11/8, putative anti-ageing factor, with cardiovascular outcomes and overall mortality in humans: analysis of the Heart and Soul and HUNT3 cohorts. Eur Heart J. 2015 Dec 21; 36(48):3426-34. PMID: 26294790; PMCID: PMC4685178 [Available on 12/21/16].
    18. Secemsky EA, Scherzer R, Nitta E, Wu AH, Lange DC, Deeks SG, Martin JN, Snider J, Ganz P, Hsue PY. Novel Biomarkers of Cardiac Stress, Cardiovascular Dysfunction, and Outcomes in HIV-Infected Individuals. JACC Heart Fail. 2015 Aug; 3(8):591-9. PMID: 26164679; PMCID: PMC4529774.
    19. Beatty AL, Ku IA, Bibbins-Domingo K, Christenson RH, DeFilippi CR, Ganz P, Ix JH, Lloyd-Jones D, Omland T, Sabatine MS, Schiller NB, Shlipak MG, Skali H, Takeuchi M, Vittinghoff E, Whooley MA. Traditional Risk Factors Versus Biomarkers for Prediction of Secondary Events in Patients With Stable Coronary Heart Disease: From the Heart and Soul Study. J Am Heart Assoc. 2015 Jul 06; 4(7). PMID: 26150476; PMCID: PMC4608062.
    20. Waldo SW, Brenner DA, McCabe JM, De la Cruz M, Long B, Narla VA, Park J, Kulkarni A, Sinclair E, Chan SY, Schick SF, Malik N, Ganz P, Hsue PY. Correction: A novel minimally-invasive method to sample human endothelial cells for molecular profiling. PLoS One. 2015; 10(5):e0126062. PMID: 25938419; PMCID: PMC4418848.
    21. Matsuzawa Y, Svedlund S, Aoki T, Guddeti RR, Kwon TG, Cilluffo R, Widmer RJ, Nelson RE, Lennon RJ, Lerman LO, Gao S, Ganz P, Gan LM, Lerman A. Utility of both carotid intima-media thickness and endothelial function for cardiovascular risk stratification in patients with angina-like symptoms. Int J Cardiol. 2015; 190:90-8. PMID: 25918056; PMCID: PMC4673663.
    22. Waldo SW, Brenner DA, McCabe JM, Dela Cruz M, Long B, Narla VA, Park J, Kulkarni A, Sinclair E, Chan SY, Schick SF, Malik N, Ganz P, Hsue PY. A novel minimally-invasive method to sample human endothelial cells for molecular profiling. PLoS One. 2015; 10(2):e0118081. PMID: 25679506.
      View in: PubMed
    23. Hsue PY, Scherzer R, Grunfeld C, Imboden J, Wu Y, Del Puerto G, Nitta E, Shigenaga J, Schnell Heringer A, Ganz P, Graf J. Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis. J Am Heart Assoc. 2014 Oct 21; 3(5):e001267. PMID: 25336464; PMCID: PMC4323827.
    24. Fang SC, Rosen RC, Vita JA, Ganz P, Kupelian V. Changes in erectile dysfunction over time in relation to Framingham cardiovascular risk in the Boston Area Community Health (BACH) Survey. J Sex Med. 2015 Jan; 12(1):100-8. PMID: 25293632; PMCID: PMC4304913.
    25. Gerber RE, Vita JA, Ganz P, Wager CG, Araujo AB, Rosen RC, Kupelian V. Association of peripheral microvascular dysfunction and erectile dysfunction. J Urol. 2015 Feb; 193(2):612-7. PMID: 25196657.
      View in: PubMed
    26. Parikh RV, Scherzer R, Nitta EM, Leone A, Hur S, Mistry V, Macgregor JS, Martin JN, Deeks SG, Ganz P, Hsue PY. Increased levels of asymmetric dimethylarginine are associated with pulmonary arterial hypertension in HIV infection. AIDS. 2014 Feb 20; 28(4):511-9. PMID: 24469026; PMCID: PMC4149286.
    27. Waldo SW, Brenner DA, Li S, Alexander K, Ganz P. Reperfusion times and in-hospital outcomes among patients with an isolated posterior myocardial infarction: insights from the National Cardiovascular Data Registry (NCDR). Am Heart J. 2014 Mar; 167(3):350-4. PMID: 24576519.
      View in: PubMed
    28. Miner M, Nehra A, Jackson G, Bhasin S, Billups K, Burnett AL, Buvat J, Carson C, Cunningham G, Ganz P, Goldstein I, Guay A, Hackett G, Kloner RA, Kostis JB, LaFlamme KE, Montorsi P, Ramsey M, Rosen R, Sadovsky R, Seftel A, Shabsigh R, Vlachopoulos C, Wu F. All men with vasculogenic erectile dysfunction require a cardiovascular workup. Am J Med. 2014 Mar; 127(3):174-82. PMID: 24423973.
      View in: PubMed
    29. Park M, Vittinghoff E, Ganz P, Peralta CA, Whooley M, Shlipak MG. Role of soluble endothelial cell-selective adhesion molecule biomarker in albuminuria and kidney function changes in patients with coronary artery disease: the Heart and Soul Study. Arterioscler Thromb Vasc Biol. 2014 Jan; 34(1):231-6. PMID: 24177327; PMCID: PMC4059045.
    30. McCabe JM, Armstrong EJ, Ku I, Kulkarni A, Hoffmayer KS, Bhave PD, Waldo SW, Hsue P, Stein JC, Marcus GM, Kinlay S, Ganz P. Physician accuracy in interpreting potential ST-segment elevation myocardial infarction electrocardiograms. J Am Heart Assoc. 2013 Oct 04; 2(5):e000268. PMID: 24096575; PMCID: PMC3835230.
    31. Turner TE, Waldo SW, Kulkarni A, Armstrong EJ, Hoffmayer KS, Kinlay S, Hsue P, Ganz P, McCabe JM. Long-term outcomes of patients sent emergently to the catheterization laboratory for possible primary percutaneous coronary intervention. Am J Cardiol. 2013 Dec 01; 112(11):1745-9. PMID: 24063836.
      View in: PubMed
    32. Waldo SW, Armstrong EJ, Kulkarni A, Hoffmayer KS, Hsue P, Ganz P, McCabe JM. Clinical characteristics and reperfusion times among patients with an isolated posterior myocardial infarction. J Invasive Cardiol. 2013 Aug; 25(8):371-5. PMID: 23913600.
      View in: PubMed
    33. Brenner DA, Dela Cruz M, Thomas K, McCabe JM, Ganz P, Hsue PY, Waldo SW. Emergency medical service utilization and door-to-balloon time for HIV-infected individuals with ST-elevation myocardial infarction. Int J Cardiol. 2013 Oct 12; 168(5):4808-9. PMID: 23871355.
      View in: PubMed
    34. Ganz P, Hsue PY. Endothelial dysfunction in coronary heart disease is more than a systemic process. Eur Heart J. 2013 Jul; 34(27):2025-7. PMID: 23756335.
      View in: PubMed
    35. Parikh RV, Scherzer R, Grunfeld C, Nitta EM, Leone A, Martin JN, Deeks SG, Ganz P, Hsue PY. Elevated levels of asymmetric dimethylarginine are associated with lower CD4+ count and higher viral load in HIV-infected individuals. Atherosclerosis. 2013 Jul; 229(1):246-52. PMID: 23711612.
      View in: PubMed
    36. Kanaya AM, Dobrosielski DA, Ganz P, Creasman J, Gupta R, Nelacanti V, Vogel-Claussen J, Herrington D. Glycemic associations with endothelial function and biomarkers among 5 ethnic groups: the Multi-Ethnic Study of Atherosclerosis and the Mediators of Atherosclerosis in South Asians Living in America studies. J Am Heart Assoc. 2013 Feb 06; 2(1):e004283. PMID: 23525433; PMCID: PMC3603246.
    37. Waldo SW, Armstrong EJ, Kulkarni A, Hoffmayer K, Kinlay S, Hsue P, Ganz P, McCabe JM. Comparison of clinical characteristics and outcomes of cardiac arrest survivors having versus not having coronary angiography. Am J Cardiol. 2013 May 01; 111(9):1253-8. PMID: 23391104.
      View in: PubMed
    38. Zamani P, Schwartz GG, Olsson AG, Rifai N, Bao W, Libby P, Ganz P, Kinlay S. Inflammatory biomarkers, death, and recurrent nonfatal coronary events after an acute coronary syndrome in the MIRACL study. J Am Heart Assoc. 2013 Jan 28; 2(1):e003103. PMID: 23525424; PMCID: PMC3603244.
    39. McCabe JM, Armstrong EJ, Hoffmayer KS, Bhave PD, MacGregor JS, Hsue P, Stein JC, Kinlay S, Ganz P. Impact of door-to-activation time on door-to-balloon time in primary percutaneous coronary intervention for ST-segment elevation myocardial infarctions: a report from the Activate-SF registry. Circ Cardiovasc Qual Outcomes. 2012 Sep 01; 5(5):672-9. PMID: 22949494.
      View in: PubMed
    40. Flammer AJ, Anderson T, Celermajer DS, Creager MA, Deanfield J, Ganz P, Hamburg NM, Lüscher TF, Shechter M, Taddei S, Vita JA, Lerman A. The assessment of endothelial function: from research into clinical practice. Circulation. 2012 Aug 07; 126(6):753-67. PMID: 22869857; PMCID: PMC3427943.
    41. Armstrong EJ, Kulkarni AR, Bhave PD, Hoffmayer KS, Macgregor JS, Stein JC, Kinlay S, Ganz P, McCabe JM. Electrocardiographic criteria for ST-elevation myocardial infarction in patients with left ventricular hypertrophy. Am J Cardiol. 2012 Oct 01; 110(7):977-83. PMID: 22738872.
      View in: PubMed
    42. McCabe JM, Armstrong EJ, Kulkarni A, Hoffmayer KS, Bhave PD, Garg S, Patel A, MacGregor JS, Hsue P, Stein JC, Kinlay S, Ganz P. Prevalence and factors associated with false-positive ST-segment elevation myocardial infarction diagnoses at primary percutaneous coronary intervention–capable centers: a report from the Activate-SF registry. Arch Intern Med. 2012 Jun 11; 172(11):864-71. PMID: 22566489.
      View in: PubMed
    43. Miner M, Seftel AD, Nehra A, Ganz P, Kloner RA, Montorsi P, Vlachopoulos C, Ramsey M, Sigman M, Tilkemeier P, Jackson G. Prognostic utility of erectile dysfunction for cardiovascular disease in younger men and those with diabetes. Am Heart J. 2012 Jul; 164(1):21-8. PMID: 22795278.
      View in: PubMed
    44. Ho JE, Scherzer R, Hecht FM, Maka K, Selby V, Martin JN, Ganz P, Deeks SG, Hsue PY. The association of CD4+ T-cell counts and cardiovascular risk in treated HIV disease. AIDS. 2012 Jun 01; 26(9):1115-20. PMID: 22382147; PMCID: PMC3881548.
    45. Frey PF, Ganz P, Hsue PY, Benowitz NL, Glantz SA, Balmes JR, Schick SF. The exposure-dependent effects of aged secondhand smoke on endothelial function. J Am Coll Cardiol. 2012 May 22; 59(21):1908-13. PMID: 22595411.
      View in: PubMed
    46. Hsue PY, Scherzer R, Hunt PW, Schnell A, Bolger AF, Kalapus SC, Maka K, Martin JN, Ganz P, Deeks SG. Carotid Intima-Media Thickness Progression in HIV-Infected Adults Occurs Preferentially at the Carotid Bifurcation and Is Predicted by Inflammation. J Am Heart Assoc. 2012 Apr; 1(2). PMID: 23130122; PMCID: PMC3487373.
    47. Armstrong EJ, Kulkarni AR, Hoffmayer KS, Bhave PD, MacGregor JS, Hsue P, Stein JC, Kinlay S, Ganz P, McCabe JM. Delaying primary percutaneous coronary intervention for computed tomographic scans in the emergency department. Am J Cardiol. 2012 Aug 01; 110(3):345-9. PMID: 22534052.
      View in: PubMed
    48. Zamani P, Ganz P, Libby P, Sutradhar SC, Rifai N, Nicholls SJ, Nissen SE, Kinlay S. Relationship of antihypertensive treatment to plasma markers of vascular inflammation and remodeling in the Comparison of Amlodipine versus Enalapril to Limit Occurrences of Thrombosis study. Am Heart J. 2012 Apr; 163(4):735-40. PMID: 22520542.
      View in: PubMed
    49. Hong TT, Cogswell R, James CA, Kang G, Pullinger CR, Malloy MJ, Kane JP, Wojciak J, Calkins H, Scheinman MM, Tseng ZH, Ganz P, De Marco T, Judge DP, Shaw RM. Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy. Heart Rhythm. 2012 Jun; 9(6):961-7. PMID: 22300662; PMCID: PMC3349006.
    50. Hsue PY, Ordovas K, Lee T, Reddy G, Gotway M, Schnell A, Ho JE, Selby V, Madden E, Martin JN, Deeks SG, Ganz P, Waters DD. Carotid intima-media thickness among human immunodeficiency virus-infected patients without coronary calcium. Am J Cardiol. 2012 Mar 01; 109(5):742-7. PMID: 22169125; PMCID: PMC3640832.
    51. Secemsky EA, Lange D, Ho JE, Brayton K, Ganz P, Farr G, Macgregor JS, Hsue PY. Improvement in revascularization time after creation of a coronary catheterization laboratory at a public hospital. Arch Intern Med. 2012 Jan 23; 172(2):193-4. PMID: 22123753.
      View in: PubMed
    52. Bhave PD, Hoffmayer KS, Armstrong EJ, Garg S, Patel A, Macgregor JS, Stein JC, Kinlay S, Ganz P, McCabe JM. Predictors of depressed left ventricular function in patients presenting with ST-elevation myocardial infarction. Am J Cardiol. 2012 Feb 01; 109(3):327-31. PMID: 22078964.
      View in: PubMed
    53. Di Carli MF, Charytan D, McMahon GT, Ganz P, Dorbala S, Schelbert HR. Coronary circulatory function in patients with the metabolic syndrome. J Nucl Med. 2011 Sep; 52(9):1369-77. PMID: 21849399.
      View in: PubMed
    54. Welles CC, Whooley MA, Na B, Ganz P, Schiller NB, Turakhia MP. The CHADS2 score predicts ischemic stroke in the absence of atrial fibrillation among subjects with coronary heart disease: data from the Heart and Soul Study. Am Heart J. 2011 Sep; 162(3):555-61. PMID: 21884876; PMCID: PMC3199107.
    55. Dubin R, Owens C, Gasper W, Ganz P, Johansen K. Associations of endothelial dysfunction and arterial stiffness with intradialytic hypotension and hypertension. Hemodial Int. 2011 Jul; 15(3):350-8. PMID: 21658174; PMCID: PMC3143472.
    56. Morishige K, Kacher DF, Libby P, Josephson L, Ganz P, Weissleder R, Aikawa M. High-resolution magnetic resonance imaging enhanced with superparamagnetic nanoparticles measures macrophage burden in atherosclerosis. Circulation. 2010 Oct 26; 122(17):1707-15. PMID: 20937980; PMCID: PMC3003265.
    57. Friedewald VE, Ganz P, Kremer JM, Mease PJ, O'Dell JR, Pearson TA, Ram CV, Ridker PM, Salmon JE, Roberts WC. AJC editor's consensus: rheumatoid arthritis and atherosclerotic cardiovascular disease. Am J Cardiol. 2010 Aug 01; 106(3):442-7. PMID: 20643261.
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    58. Ho JE, Deeks SG, Hecht FM, Xie Y, Schnell A, Martin JN, Ganz P, Hsue PY. Initiation of antiretroviral therapy at higher nadir CD4+ T-cell counts is associated with reduced arterial stiffness in HIV-infected individuals. AIDS. 2010 Jul 31; 24(12):1897-905. PMID: 20543654; PMCID: PMC2903431.
    59. Edelbauer M, Datta D, Vos IH, Basu A, Stack MP, Reinders ME, Sho M, Calzadilla K, Ganz P, Briscoe DM. Effect of vascular endothelial growth factor and its receptor KDR on the transendothelial migration and local trafficking of human T cells in vitro and in vivo. Blood. 2010 Sep 16; 116(11):1980-9. PMID: 20538805; PMCID: PMC3173992.
    60. Araujo AB, Hall SA, Ganz P, Chiu GR, Rosen RC, Kupelian V, Travison TG, McKinlay JB. Does erectile dysfunction contribute to cardiovascular disease risk prediction beyond the Framingham risk score? J Am Coll Cardiol. 2010 Jan 26; 55(4):350-6. PMID: 20117441; PMCID: PMC2845313.
    61. Ganz P, Hsue PY. Assessment of structural disease in the coronary microvasculature. Circulation. 2009 Oct 20; 120(16):1555-7. PMID: 19805646.
      View in: PubMed
    62. Hsue PY, Hunt PW, Wu Y, Schnell A, Ho JE, Hatano H, Xie Y, Martin JN, Ganz P, Deeks SG. Association of abacavir and impaired endothelial function in treated and suppressed HIV-infected patients. AIDS. 2009 Sep 24; 23(15):2021-7. PMID: 19542863; PMCID: PMC2785446.
    63. Beltrame JF, Ganz P. Evaluating patients with persistent chest pain and no obstructive coronary artery disease. JAMA. 2009 Aug 12; 302(6):622-3; author reply 623-4. PMID: 19671898.
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    64. Larose E, Behrendt D, Kinlay S, Selwyn AP, Ganz P, Fang JC. Endothelin-1 is a key mediator of coronary vasoconstriction in patients with transplant coronary arteriosclerosis. Circ Heart Fail. 2009 Sep; 2(5):409-16. PMID: 19808370.
      View in: PubMed
    65. Araujo AB, Travison TG, Ganz P, Chiu GR, Kupelian V, Rosen RC, Hall SA, McKinlay JB. Erectile dysfunction and mortality. J Sex Med. 2009 Sep; 6(9):2445-54. PMID: 19538544; PMCID: PMC3524836.
    66. Fraley AE, Schwartz GG, Olsson AG, Kinlay S, Szarek M, Rifai N, Libby P, Ganz P, Witztum JL, Tsimikas S. Relationship of oxidized phospholipids and biomarkers of oxidized low-density lipoprotein with cardiovascular risk factors, inflammatory biomarkers, and effect of statin therapy in patients with acute coronary syndromes: Results from the MIRACL (Myocardial Ischemia Reduction With Aggressive Cholesterol Lowering) trial. J Am Coll Cardiol. 2009 Jun 09; 53(23):2186-96. PMID: 19497447.
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    67. Ganz P, Ho JE, Hsue PY. Structural and functional manifestations of human atherosclerosis: do they run in parallel? Eur Heart J. 2009 Jul; 30(13):1556-8. PMID: 19502231.
      View in: PubMed
    68. Hsue PY, Hunt PW, Schnell A, Kalapus SC, Hoh R, Ganz P, Martin JN, Deeks SG. Role of viral replication, antiretroviral therapy, and immunodeficiency in HIV-associated atherosclerosis. AIDS. 2009 Jun 01; 23(9):1059-67. PMID: 19390417; PMCID: PMC2691772.
    69. Ku IA, Imboden JB, Hsue PY, Ganz P. Rheumatoid arthritis: model of systemic inflammation driving atherosclerosis. Circ J. 2009 Jun; 73(6):977-85. PMID: 19430165.
      View in: PubMed
    70. Kinlay S, Schwartz GG, Olsson AG, Rifai N, Bao W, Libby P, Ganz P. Endogenous tissue plasminogen activator and risk of recurrent cardiac events after an acute coronary syndrome in the MIRACL study. Atherosclerosis. 2009 Oct; 206(2):551-5. PMID: 19394618.
      View in: PubMed
    71. Ganz P, Hsue PY. Individualized approach to the management of coronary heart disease: identifying the nonresponders before it is too late. J Am Coll Cardiol. 2009 Jan 27; 53(4):331-3. PMID: 19161881.
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    72. Rawlings R, Nohria A, Liu PY, Donnelly J, Creager MA, Ganz P, Selwyn A, Liao JK. Comparison of effects of rosuvastatin (10 mg) versus atorvastatin (40 mg) on rho kinase activity in caucasian men with a previous atherosclerotic event. Am J Cardiol. 2009 Feb 15; 103(4):437-41. PMID: 19195498; PMCID: PMC2673911.
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    74. Serruys PW, García-García HM, Buszman P, Erne P, Verheye S, Aschermann M, Duckers H, Bleie O, Dudek D, Bøtker HE, von Birgelen C, D'Amico D, Hutchinson T, Zambanini A, Mastik F, van Es GA, van der Steen AF, Vince DG, Ganz P, Hamm CW, Wijns W, Zalewski A. Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque. Circulation. 2008 Sep 09; 118(11):1172-82. PMID: 18765397.
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    76. Larose E, Kinlay S, Selwyn AP, Yeghiazarians Y, Yucel EK, Kacher DF, Libby P, Ganz P. Improved characterization of atherosclerotic plaques by gadolinium contrast during intravascular magnetic resonance imaging of human arteries. Atherosclerosis. 2008 Feb; 196(2):919-25. PMID: 17391676.
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    77. Larose E, Ganz P, Reynolds HG, Dorbala S, Di Carli MF, Brown KA, Kwong RY. Right ventricular dysfunction assessed by cardiovascular magnetic resonance imaging predicts poor prognosis late after myocardial infarction. J Am Coll Cardiol. 2007 Feb 27; 49(8):855-62. PMID: 17320743.
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    81. Behrendt D, Beltrame J, Hikiti H, Wainstein M, Kinlay S, Selwyn AP, Ganz P, Fang JC. Impact of coronary endothelial function on the progression of cardiac transplant-associated arteriosclerosis: effect of anti-oxidant vitamins C and E. J Heart Lung Transplant. 2006 Apr; 25(4):426-33. PMID: 16563973.
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    82. Nissen SE, Tuzcu EM, Brewer HB, Sipahi I, Nicholls SJ, Ganz P, Schoenhagen P, Waters DD, Pepine CJ, Crowe TD, Davidson MH, Deanfield JE, Wisniewski LM, Hanyok JJ, Kassalow LM. Effect of ACAT inhibition on the progression of coronary atherosclerosis. N Engl J Med. 2006 Mar 23; 354(12):1253-63. PMID: 16554527.
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    83. Kostis JB, Jackson G, Rosen R, Barrett-Connor E, Billups K, Burnett AL, Carson C, Cheitlin M, Debusk R, Fonseca V, Ganz P, Goldstein I, Guay A, Hatzichristou D, Hollander JE, Hutter A, Katz S, Kloner RA, Mittleman M, Montorsi F, Montorsi P, Nehra A, Sadovsky R, Shabsigh R. Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference). Am J Cardiol. 2005 Dec 26; 96(12B):85M-93M. PMID: 16387575.
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    85. Ganz P. Erectile dysfunction: pathophysiologic mechanisms pointing to underlying cardiovascular disease. Am J Cardiol. 2005 Dec 26; 96(12B):8M-12M. PMID: 16387559.
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    86. Kostis JB, Jackson G, Rosen R, Barrett-Connor E, Billups K, Burnett AL, Carson C, Cheitlin M, Debusk R, Fonseca V, Ganz P, Goldstein I, Guay A, Hatzichristou D, Hollander JE, Hutter A, Katz S, Kloner RA, Mittleman M, Montorsi F, Montorsi P, Nehra A, Sadovsky R, Shabsigh R. Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference). Am J Cardiol. 2005 Jul 15; 96(2):313-21. PMID: 16018863.
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    87. Olsson AG, Schwartz GG, Szarek M, Sasiela WJ, Ezekowitz MD, Ganz P, Oliver MF, Waters D, Zeiher A. High-density lipoprotein, but not low-density lipoprotein cholesterol levels influence short-term prognosis after acute coronary syndrome: results from the MIRACL trial. Eur Heart J. 2005 May; 26(9):890-6. PMID: 15764620.
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    88. Nissen SE, Tuzcu EM, Schoenhagen P, Crowe T, Sasiela WJ, Tsai J, Orazem J, Magorien RD, O'Shaughnessy C, Ganz P. Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease. N Engl J Med. 2005 Jan 06; 352(1):29-38. PMID: 15635110.
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    89. Larose E, Ganz P. Statins and endothelial dysfunction. Semin Vasc Med. 2004 Nov; 4(4):333-46. PMID: 15861315.
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    90. Hamburg NM, Charbonneau F, Gerhard-Herman M, Ganz P, Creager MA. Comparison of endothelial function in young men and women with a family history of premature coronary artery disease. Am J Cardiol. 2004 Sep 15; 94(6):783-5. PMID: 15374789.
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    91. Kinlay S, Schwartz GG, Olsson AG, Rifai N, Sasiela WJ, Szarek M, Ganz P, Libby P. Effect of atorvastatin on risk of recurrent cardiovascular events after an acute coronary syndrome associated with high soluble CD40 ligand in the Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) Study. Circulation. 2004 Jul 27; 110(4):386-91. PMID: 15262833.
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    92. Davignon J, Ganz P. Role of endothelial dysfunction in atherosclerosis. Circulation. 2004 Jun 15; 109(23 Suppl 1):III27-32. PMID: 15198963.
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    93. Nissen SE, Tuzcu EM, Schoenhagen P, Brown BG, Ganz P, Vogel RA, Crowe T, Howard G, Cooper CJ, Brodie B, Grines CL, DeMaria AN. Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial. JAMA. 2004 Mar 03; 291(9):1071-80. PMID: 14996776.
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    94. Kinlay S, Behrendt D, Fang JC, Delagrange D, Morrow J, Witztum JL, Rifai N, Selwyn AP, Creager MA, Ganz P. Long-term effect of combined vitamins E and C on coronary and peripheral endothelial function. J Am Coll Cardiol. 2004 Feb 18; 43(4):629-34. PMID: 14975474.
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    95. Schwartz GG, Ganz P, Waters D, Arikian S. Pharmacoeconomic evaluation of the effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes. Am J Cardiol. 2003 Nov 01; 92(9):1109-12. PMID: 14583367.
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    96. Kinlay S, Ganz P. Early statin therapy in acute coronary syndromes. Semin Vasc Med. 2003 Nov; 3(4):419-24. PMID: 15199449.
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    97. Ganz P, Vita JA. Testing endothelial vasomotor function: nitric oxide, a multipotent molecule. Circulation. 2003 Oct 28; 108(17):2049-53. PMID: 14581383.
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    98. Kinlay S, Schwartz GG, Olsson AG, Rifai N, Leslie SJ, Sasiela WJ, Szarek M, Libby P, Ganz P. High-dose atorvastatin enhances the decline in inflammatory markers in patients with acute coronary syndromes in the MIRACL study. Circulation. 2003 Sep 30; 108(13):1560-6. PMID: 12975259.
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    99. Reinders ME, Fang JC, Wong W, Ganz P, Briscoe DM. Expression patterns of vascular endothelial growth factor in human cardiac allografts: association with rejection. Transplantation. 2003 Jul 15; 76(1):224-30. PMID: 12865814.
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    100. Nohria A, Garrett L, Johnson W, Kinlay S, Ganz P, Creager MA. Endothelin-1 and vascular tone in subjects with atherogenic risk factors. Hypertension. 2003 Jul; 42(1):43-8. PMID: 12756218.
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    101. Schönbeck U, Gerdes N, Varo N, Reynolds RS, Horton DB, Bavendiek U, Robbie L, Ganz P, Kinlay S, Libby P. Oxidized low-density lipoprotein augments and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors limit CD40 and CD40L expression in human vascular cells. Circulation. 2002 Dec 03; 106(23):2888-93. PMID: 12460867.
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    102. Fang JC, Kinlay S, Behrendt D, Hikita H, Witztum JL, Selwyn AP, Ganz P. Circulating autoantibodies to oxidized LDL correlate with impaired coronary endothelial function after cardiac transplantation. Arterioscler Thromb Vasc Biol. 2002 Dec 01; 22(12):2044-8. PMID: 12482832.
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    103. Behrendt D, Ganz P. Endothelial function. From vascular biology to clinical applications. Am J Cardiol. 2002 Nov 21; 90(10C):40L-48L. PMID: 12459427.
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    104. Waters DD, Schwartz GG, Olsson AG, Zeiher A, Oliver MF, Ganz P, Ezekowitz M, Chaitman BR, Leslie SJ, Stern T. Effects of atorvastatin on stroke in patients with unstable angina or non-Q-wave myocardial infarction: a Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) substudy. Circulation. 2002 Sep 24; 106(13):1690-5. PMID: 12270864.
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    105. Kinlay S, Grewal J, Manuelin D, Fang JC, Selwyn AP, Bittl JA, Ganz P. Coronary flow velocity and disturbed flow predict adverse clinical outcome after coronary angioplasty. Arterioscler Thromb Vasc Biol. 2002 Aug 01; 22(8):1334-40. PMID: 12171797.
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    106. Johnson W, Nohria A, Garrett L, Fang JC, Igo J, Katai M, Ganz P, Creager MA. Contribution of endothelin to pulmonary vascular tone under normoxic and hypoxic conditions. Am J Physiol Heart Circ Physiol. 2002 Aug; 283(2):H568-75. PMID: 12124203.
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    107. Ganz P. Vasomotor and vascular effects of hormone replacement therapy. Am J Cardiol. 2002 Jul 03; 90(1A):11F-16F. PMID: 12106634.
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    108. Fang JC, Kinlay S, Beltrame J, Hikiti H, Wainstein M, Behrendt D, Suh J, Frei B, Mudge GH, Selwyn AP, Ganz P. Effect of vitamins C and E on progression of transplant-associated arteriosclerosis: a randomised trial. Lancet. 2002 Mar 30; 359(9312):1108-13. PMID: 11943259.
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