Kamalini Ranasinghe, MBBS, PhD

Title(s)Assistant Professor, Neurology
SchoolSchool of Medicine
Phone415-514-8847
PronounsShe/Her/Hers
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


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    Neural network dysfunction and inflammatory dysregulation in Alzheimer’s disease
    Larry L Hillblom Foundation 2019-A-013-SUPJul 1, 2019 - Jun 30, 2022
    Role: Principal Investigator
    Neurophysiological Assessments of Network Dysfunction in Alzheimer's Disease
    NIH K08AG058749May 1, 2019 - Apr 30, 2024
    Role: Principal Investigator
    Spatiotemporal Patterns of Network Dysfunction in Alzheimer's Disease
    NIH F32AG050434Mar 5, 2016 - Mar 4, 2019
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Neurophysiological signatures of ageing: compensatory and compromised neural mechanisms. Brain Communications. 2025 Mar 4; 7(2):fcaf131. Ranasinghe RK, Kudo KK, Casaletto CK, Rojas-Martinez RJ, Syed SF, Vossel VK, Miller MB, Rabinovici RG, Kramer KJ, Rankin RK, Nagarajan NS. .
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    2. Distinct associations of excitatory-inhibitory (E/I) imbalance in aging and in Alzheimer’s disease. Alzheimer's & Dementia. 2024 Dec 1; 20(Suppl 1):e091606. Ranasinghe RK, Verma VP, Kudo KK, Syed SF, Rankin RK, Miller MB, Kramer KJ, Rabinovici RG, Kirsch KH, Vossel VK, Raj RA, Nagarajan NS. .
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    3. High Frequency Oscillations in Epileptic and Non-Epileptic Alzheimer’s Disease Patients and the Effect of Levetiracetam on the Oscillations. Alzheimer's & Dementia. 2024 Dec 1; 20(Suppl 2):e089593. Chenchu CV, Addo-Osafo AK, Ranasinghe RK, Shamas SM, Staba SR, Nagaragan NS, Vossel VK. .
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    4. Abnormal gamma phase-amplitude coupling in the parahippocampal cortex is associated with network hyperexcitability in Alzheimer’s disease. Brain Communications. 2024 Apr 9; fcae121. Prabhu PP, Morise MH, Kudo KK, Beagle BA, Mizuiri MD, Syed SF, Kotegar KK, Findlay FA, Miller MB, Kramer KJ, Rankin RK, Garcia GP, Kirsch KH, Vossel VK, Nagarajan NS, Ranasinghe RK. .
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    5. Neurophysiological trajectories in Alzheimer’s disease progression. eLife. 2024 Mar 28; 12. Kudo KK, Ranasinghe RK, Morise MH, Syed SF, Sekihara SK, Rankin RK, Miller MB, Kramer KJ, Rabinovici RG, Vossel VK, Kirsch KH, Nagarajan NS. .
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    6. Neurophysiological changes associated with plasma p-tau represent functional effects of amyloid accumulation and are modulated by APOE. Alzheimer's & Dementia. 2023 Dec 25; 19(S17). Ranasinghe RK, Rojas RJ, Casaletto CK, Kudo KK, Syed SF, La Joie LR, Chan CB, Lago LA, Miller MB, Vossel VK, Kramer KJ, Boxer BA, Rankin RK, Rabinovici RG, Nagarajan NS. .
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    7. Neuronal hyperexcitability in AD. Alzheimer's & Dementia. 2023 Dec 25; 19(S12). Ranasinghe RK. .
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    8. Quantitative Amyloid-PET in Real-World Practice: Lessons from the Imaging Dementia—Evidence for Amyloid Scanning (IDEAS) study. Alzheimer's & Dementia. 2023 Dec 25; 19(S24). La Joie LR, Mundada MN, Blazhenets BG, Mejía-Perez MJ, Schonhaut SD, Zeltzer ZE, Soleimani-Meigooni SD, Cho CH, Ranasinghe RK, Windon WC, Yadollahikhales YG, Iaccarino IL, Koeppe KR, Carrillo CM, Hanna HL, Gatsonis GC, March MA, Siegel SB, Hillner HB, Whitmer WR, Rabinovici RG. .
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    9. Spectral graph modeling reveals global slowing of neurophysiological network transmission in Alzheimer’s disease. Alzheimer's & Dementia. 2023 Dec 24; 19(S10). Verma VP, Ranasinghe RK, Prasad PJ, Cai CC, Xie XX, Lerner LH, Mizuiri MD, Miller MB, Rankin RK, Vossel VK, Nagarajan NS, Raj RA. .
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    10. Abnormal gamma frequency phase-amplitude coupling associated with network hyperexcitability in Alzheimer’s Disease. Alzheimer's & Dementia. 2023 Jun 16; 19(S3). Prabhu PP, Ranasinghe RK, Morise MH, Kudo KK, Hinkley HL, Lerner LH, Mizuiri MD, Licata LA, Kotegar KK, Findlay FA, Miller MB, Gorno-Tempini GM, Kramer KJ, Rankin RK, Garcia GP, Kirsch KH, Houde HJ, Vossel VK, Nagarajan NS. .
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    11. Spectral signatures associated with cognitive aging, APOE4, amyloid-ß and measures of axonal integrity in cognitively unimpaired adults. Alzheimer's & Dementia. 2022 Dec 20; 18(S6). Ranasinghe RK, Casaletto CK, Kudo KK, Lerner LH, Mizuiri MD, La Joie LR, Miller MB, Vossel VK, Kramer KJ, Jagust JW, Rankin RK, Rabinovici RG, Nagarajan NS. .
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    12. Sleep patterns differ across Alzheimer’s disease phenotypes: Implications for selective vulnerability and customized treatment. Alzheimer's & Dementia. 2022 Feb 1; 17. Martínez MN, Ruoff RL, Essanaa EY, Le LM, You YM, Kramer KJ, Vossel VK, Neylan NT, Walsh WC, Ranasinghe RK, Grinberg GL. .
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    13. Abnormal neural oscillations depicting excitatory-inhibitory imbalance are distinctly associated with amyloid and tau depositions in Alzheimer's disease. Alzheimer's & Dementia. 2021 Dec 1; 17(S4). Ranasinghe RK, Verma VP, Cai CC, Xie XX, Kudo KK, Gao GX, Lerner LH, Mizuiri MD, Strom SA, Iaccarino IL, La Joie LR, Miller MB, Tempini TM, Rankin RK, Jagust JW, Vossel VK, Rabinovici RG, Raj RA, Nagarajan NS. .
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    14. 073 Whole-brain network analysis of neural oscillations during light sleep. Sleep. 2021 May 3; 44(Supplement_2):a30-a31. Fan FJ, Kudo KK, Ranasinghe RK, Morise MH, Findlay FA, Kirsch KH, Krystal KA, Nagarajan NS. .
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    15. Alpha-frequency synchronization deficits during life predict postmortem neurofibrillary tangle burden in Alzheimer’s disease. Alzheimer's & Dementia. 2020 Dec 7; 16(S4). Ranasinghe RK, Petersen PC, Kudo KK, Srivatsan SS, Beagle BA, Mizuiri MD, Findlay FA, Houde HJ, Rankin RK, Rabinovici RG, Seeley SW, Spina SS, Gorno-Tempini GM, Kramer KJ, Miller MB, Vossel VK, Grinberg GL, Nagarajan NS. .
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    16. Neurophysiological signatures in Alzheimer's disease are distinctly associated with TAU, amyloid-β accumulation, and cognitive decline. Sci Transl Med. 2020 03 11; 12(534). Ranasinghe KG, Cha J, Iaccarino L, Hinkley LB, Beagle AJ, Pham J, Jagust WJ, Miller BL, Rankin KP, Rabinovici GD, Vossel KA, Nagarajan SS. PMID: 32161102; PMCID: PMC7138514.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    17. NEURAL ACTIVITY PATTERNS UNDERLYING ABNORMAL PHONOLOGICAL PROCESSING IN PATIENTS WITH LOGOPENIC VARIANT PRIMARY PROGRESSIVE APHASIA. Alzheimer's & Dementia. 2019 Jul 1; 15(7):p757. Ranasinghe RK, Beagle BA, Mizuiri MD, Honma HS, Welch WA, Tempini TM, Vossel VK, Houde HJ, Nagarajan NS. .
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    18. Neural correlates of abnormal auditory feedback processing during speech production in Alzheimer's disease. Sci Rep. 2019 04 05; 9(1):5686. Ranasinghe KG, Kothare H, Kort N, Hinkley LB, Beagle AJ, Mizuiri D, Honma SM, Lee R, Miller BL, Gorno-Tempini ML, Vossel KA, Houde JF, Nagarajan SS. PMID: 30952883; PMCID: PMC6450891.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    19. DISTINCT NEURAL OSCILLATION ABNORMALITIES ASSOCIATED WITH AMYLOID-BETA AND TAU IN ALZHEIMER’S DISEASE. Alzheimer's & Dementia. 2018 Jul 1; 14(7):p213-p214. Ranasinghe RK, Cha CJ, Hinkley HL, Beagle BA, Mizuiri MD, Honma HS, Bourakova BV, Jagust JW, Miller MB, Rabinovici RG, Nagarajan NS, Vossel VK. .
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    20. Abnormal vocal behavior predicts executive and memory deficits in Alzheimer's disease. Neurobiol Aging. 2017 04; 52:71-80. Ranasinghe KG, Gill JS, Kothare H, Beagle AJ, Mizuiri D, Honma SM, Gorno-Tempini ML, Miller BL, Vossel KA, Nagarajan SS, Houde JF. PMID: 28131013; PMCID: PMC5359035.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    21. Distinct Subtypes of Behavioral Variant Frontotemporal Dementia Based on Patterns of Network Degeneration. JAMA Neurol. 2016 Sep 01; 73(9):1078-88. Ranasinghe KG, Rankin KP, Pressman PS, Perry DC, Lobach IV, Seeley WW, Coppola G, Karydas AM, Grinberg LT, Shany-Ur T, Lee SE, Rabinovici GD, Rosen HJ, Gorno-Tempini ML, Boxer AL, Miller ZA, Chiong W, DeMay M, Kramer JH, Possin KL, Sturm VE, Bettcher BM, Neylan M, Zackey DD, Nguyen LA, Ketelle R, Block N, Wu TQ, Dallich A, Russek N, Caplan A, Geschwind DH, Vossel KA, Miller BL. PMID: 27429218; PMCID: PMC5024785.
      View in: PubMed   Mentions: 78     Fields:    Translation:Humans
    22. Chapter 15 Brain Imaging With Magnetoencephalography During Rest and During Speech and Language Processing. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry. 2016 Jan 1; 233-245. Nagarajan NS, Ranasinghe RK, Vossel VK. .
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    23. Region Specific Alpha-Band Resting-State Functional Connectivity Predicts Focal Cognitive Deficits In Alzheimer’s Disease Spectrum (P6.318). Neurology. 2014 Apr 8; 82(10_supplement). Ranasinghe RK, Hinkley HL, Beagle BA, Mizuiri MD, Dowling DA, Honma HS, Finucane FM, Scherling SC, Miller MB, Nagarajan NS, Vossel VK. .
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    24. Clinical Characteristics of bvFTD Across CDR Stages (P3.201). Neurology. 2014 Apr 8; 82(10_supplement). Ranasinghe RK, Pressman PP, Perry PD, Rankin RK, Miller MB. .
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    25. Increasing diversity of neural responses to speech sounds across the central auditory pathway. Neuroscience. 2013 Nov 12; 252:80-97. Ranasinghe KG, Vrana WA, Matney CJ, Kilgard MP. PMID: 23954862; PMCID: PMC3795858.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    26. Neural mechanisms supporting robust discrimination of spectrally and temporally degraded speech. J Assoc Res Otolaryngol. 2012 Aug; 13(4):527-42. Ranasinghe KG, Vrana WA, Matney CJ, Kilgard MP. PMID: 22549175; PMCID: PMC3387312.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    27. Speech discrimination after early exposure to pulsed-noise or speech. Hear Res. 2012 Jul; 289(1-2):1-12. Ranasinghe KG, Carraway RS, Borland MS, Moreno NA, Hanacik EA, Miller RS, Kilgard MP. PMID: 22575207; PMCID: PMC3477610.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsPHPublic Health
    28. Weight loss via diet and exercise improves exercise breathing mechanics in obese men. Chest. 2011 Aug; 140(2):454-460. Babb TG, Wyrick BL, Chase PJ, DeLorey DS, Rodder SG, Feng MY, Ranasinghe KG. PMID: 21273293.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    29. Discrimination of brief speech sounds is impaired in rats with auditory cortex lesions. Behav Brain Res. 2011 May 16; 219(1):68-74. Porter BA, Rosenthal TR, Ranasinghe KG, Kilgard MP. PMID: 21167211; PMCID: PMC3062672.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    30. Dyspnea on exertion in obese women: association with an increased oxygen cost of breathing. Am J Respir Crit Care Med. 2008 Jul 15; 178(2):116-23. Babb TG, Ranasinghe KG, Comeau LA, Semon TL, Schwartz B. PMID: 18420968.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    31. Short-term modulation of the exercise ventilatory response is not diminished in older men. The FASEB Journal. 2008 Mar 1; 22:1233.9-1233.9. Wood WH, Rowell RC, Storms SC, Klocko KM, Ranasinghe RK, Mitchell MG, Babb BT. .
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    32. The exercise ventilatory response does not differ between obese women with and without dyspnea on exertion. The FASEB Journal. 2007 Jan 1; 21(6):a929-a929. Wood WH, Semon ST, Comeau CL, Schwartz SB, MacDougall MR, Klocko KM, Ranasinghe RK, Babb BT. .
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    33. Short-term modulation of the exercise ventilatory response in humans. The FASEB Journal. 2007 Jan 1; 21(6):a932-a933. Wood WH, Klocko KM, Ranasinghe RK, Mitchell MG, Babb BT. .
      View in: Publisher Site   Mentions:
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