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David Perry, MD

Title(s)Assistant Professor, Neurology
SchoolSchool of Medicine
Phone415-476-8678
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Research 
    Collapse Research Activities and Funding
    Reward processing in genetic frontotemporal dementia and mood disorders
    NIH/NIA R01AG059794Mar 1, 2019 - Dec 31, 2023
    Role: Principal Investigator
    Reward processing in frontotemporal dementia
    NIH/NIA K23AG045289Aug 15, 2014 - Jun 30, 2019
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. La Joie R, Visani AV, Baker SL, Brown JA, Bourakova V, Cha J, Chaudhary K, Edwards L, Iaccarino L, Janabi M, Lesman-Segev OH, Miller ZA, Perry DC, O'Neil JP, Pham J, Rojas JC, Rosen HJ, Seeley WW, Tsai RM, Miller BL, Jagust WJ, Rabinovici GD. Prospective longitudinal atrophy in Alzheimer's disease correlates with the intensity and topography of baseline tau-PET. Sci Transl Med. 2020 01 01; 12(524). PMID: 31894103.
      View in: PubMed
    2. Lesman-Segev OH, La Joie R, Stephens ML, Sonni I, Tsai R, Bourakova V, Visani AV, Edwards L, O'Neil JP, Baker SL, Gardner RC, Janabi M, Chaudhary K, Perry DC, Kramer JH, Miller BL, Jagust WJ, Rabinovici GD. Tau PET and multimodal brain imaging in patients at risk for chronic traumatic encephalopathy. Neuroimage Clin. 2019; 24:102025. PMID: 31670152.
      View in: PubMed
    3. Takeda A, Sturm VE, Rankin KP, Ketelle R, Miller BL, Perry DC. Relationship Turmoil and Emotional Empathy in Frontotemporal Dementia. Alzheimer Dis Assoc Disord. 2019 Jul-Sep; 33(3):260-265. PMID: 31135456.
      View in: PubMed
    4. Perry DC, Datta S, Miller ZA, Rankin KP, Gorno-Tempini ML, Kramer JH, Rosen HJ, Seeley WW, Miller BL. Factors that predict diagnostic stability in neurodegenerative dementia. J Neurol. 2019 Aug; 266(8):1998-2009. PMID: 31102021.
      View in: PubMed
    5. Butler PM, Chiong W, Perry DC, Miller ZA, Gennatas ED, Brown JA, Pasquini L, Karydas A, Dokuru D, Coppola G, Sturm VE, Boxer AL, Gorno-Tempini ML, Rosen HJ, Kramer JH, Miller BL, Seeley WW. Dopamine receptor D4 (DRD4) polymorphisms with reduced functional potency intensify atrophy in syndrome-specific sites of frontotemporal dementia. Neuroimage Clin. 2019; 23:101822. PMID: 31003069.
      View in: PubMed
    6. Tsai RM, Bejanin A, Lesman-Segev O, LaJoie R, Visani A, Bourakova V, O'Neil JP, Janabi M, Baker S, Lee SE, Perry DC, Bajorek L, Karydas A, Spina S, Grinberg LT, Seeley WW, Ramos EM, Coppola G, Gorno-Tempini ML, Miller BL, Rosen HJ, Jagust W, Boxer AL, Rabinovici GD. 18F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes. Alzheimers Res Ther. 2019 01 31; 11(1):13. PMID: 30704514.
      View in: PubMed
    7. Sturm VE, Sible IJ, Datta S, Hua AY, Perry DC, Kramer JH, Miller BL, Seeley WW, Rosen HJ. Resting parasympathetic dysfunction predicts prosocial helping deficits in behavioral variant frontotemporal dementia. Cortex. 2018 12; 109:141-155. PMID: 30317048.
      View in: PubMed
    8. Hua AY, Sible IJ, Perry DC, Rankin KP, Kramer JH, Miller BL, Rosen HJ, Sturm VE. Enhanced Positive Emotional Reactivity Undermines Empathy in Behavioral Variant Frontotemporal Dementia. Front Neurol. 2018; 9:402. PMID: 29915557.
      View in: PubMed
    9. Seo SW, Thibodeau MP, Perry DC, Hua A, Sidhu M, Sible I, Vargas JNS, Gaus SE, Rabinovici GD, Rankin KD, Boxer AL, Kramer JH, Rosen HJ, Gorno-Tempini ML, Grinberg LT, Huang EJ, DeArmond SJ, Trojanowski JQ, Miller BL, Seeley WW. Early vs late age at onset frontotemporal dementia and frontotemporal lobar degeneration. Neurology. 2018 03 20; 90(12):e1047-e1056. PMID: 29453245.
      View in: PubMed
    10. Perry DC, Datta S, Sturm VE, Wood KA, Zakrzewski J, Seeley WW, Miller BL, Kramer JH, Rosen HJ. Reward deficits in behavioural variant frontotemporal dementia include insensitivity to negative stimuli. Brain. 2017 Dec 01; 140(12):3346-3356. PMID: 29053832.
      View in: PubMed
    11. Perry DC, Brown JA, Possin KL, Datta S, Trujillo A, Radke A, Karydas A, Kornak J, Sias AC, Rabinovici GD, Gorno-Tempini ML, Boxer AL, De May M, Rankin KP, Sturm VE, Lee SE, Matthews BR, Kao AW, Vossel KA, Tartaglia MC, Miller ZA, Seo SW, Sidhu M, Gaus SE, Nana AL, Vargas JNS, Hwang JL, Ossenkoppele R, Brown AB, Huang EJ, Coppola G, Rosen HJ, Geschwind D, Trojanowski JQ, Grinberg LT, Kramer JH, Miller BL, Seeley WW. Clinicopathological correlations in behavioural variant frontotemporal dementia. Brain. 2017 Dec 01; 140(12):3329-3345. PMID: 29053860.
      View in: PubMed
    12. Sturm VE, Perry DC, Wood K, Hua AY, Alcantar O, Datta S, Rankin KP, Rosen HJ, Miller BL, Kramer JH. Prosocial deficits in behavioral variant frontotemporal dementia relate to reward network atrophy. Brain Behav. 2017 10; 7(10):e00807. PMID: 29075567.
      View in: PubMed
    13. Fernández-Fournier M, Perry DC, Tartaglia MC, de May M, Boxer A, Coppola G, Christine CW, Huang EJ, Seeley WW, Miller BL, DeArmond SJ, Grinberg LT, Geschwind MD. Precipitous Deterioration of Motor Function, Cognition, and Behavior. JAMA Neurol. 2017 05 01; 74(5):591-596. PMID: 28264087.
      View in: PubMed
    14. Krabbe G, Minami SS, Etchegaray JI, Taneja P, Djukic B, Davalos D, Le D, Lo I, Zhan L, Reichert MC, Sayed F, Merlini M, Ward ME, Perry DC, Lee SE, Sias A, Parkhurst CN, Gan WB, Akassoglou K, Miller BL, Farese RV, Gan L. Microglial NF?B-TNFa hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia. Proc Natl Acad Sci U S A. 2017 05 09; 114(19):5029-5034. PMID: 28438992.
      View in: PubMed
    15. Spina S, Schonhaut DR, Boeve BF, Seeley WW, Ossenkoppele R, O'Neil JP, Lazaris A, Rosen HJ, Boxer AL, Perry DC, Miller BL, Dickson DW, Parisi JE, Jagust WJ, Murray ME, Rabinovici GD. Frontotemporal dementia with the V337M MAPT mutation: Tau-PET and pathology correlations. Neurology. 2017 Feb 21; 88(8):758-766. PMID: 28130473.
      View in: PubMed
    16. Ranasinghe KG, Rankin KP, Pressman PS, Perry DC, Lobach IV, Seeley WW, Coppola G, Karydas AM, Grinberg LT, Shany-Ur T, Lee SE, Rabinovici GD, Rosen HJ, Gorno-Tempini ML, Boxer AL, Miller ZA, Chiong W, DeMay M, Kramer JH, Possin KL, Sturm VE, Bettcher BM, Neylan M, Zackey DD, Nguyen LA, Ketelle R, Block N, Wu TQ, Dallich A, Russek N, Caplan A, Geschwind DH, Vossel KA, Miller BL. Distinct Subtypes of Behavioral Variant Frontotemporal Dementia Based on Patterns of Network Degeneration. JAMA Neurol. 2016 Sep 01; 73(9):1078-88. PMID: 27429218.
      View in: PubMed
    17. Ranasinghe KG, Rankin KP, Lobach IV, Kramer JH, Sturm VE, Bettcher BM, Possin K, Christine You S, Lamarre AK, Shany-Ur T, Stephens ML, Perry DC, Lee SE, Miller ZA, Gorno-Tempini ML, Rosen HJ, Boxer A, Seeley WW, Rabinovici GD, Vossel KA, Miller BL. Cognition and neuropsychiatry in behavioral variant frontotemporal dementia by disease stage. Neurology. 2016 Feb 16; 86(7):600-10. PMID: 26802093.
      View in: PubMed
    18. Perry DC, Sturm VE, Peterson MJ, Pieper CF, Bullock T, Boeve BF, Miller BL, Guskiewicz KM, Berger MS, Kramer JH, Welsh-Bohmer KA. Association of traumatic brain injury with subsequent neurological and psychiatric disease: a meta-analysis. J Neurosurg. 2016 Feb; 124(2):511-26. PMID: 26315003.
      View in: PubMed
    19. Ossenkoppele R, Pijnenburg YA, Perry DC, Cohn-Sheehy BI, Scheltens NM, Vogel JW, Kramer JH, van der Vlies AE, La Joie R, Rosen HJ, van der Flier WM, Grinberg LT, Rozemuller AJ, Huang EJ, van Berckel BN, Miller BL, Barkhof F, Jagust WJ, Scheltens P, Seeley WW, Rabinovici GD. The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features. Brain. 2015 Sep; 138(Pt 9):2732-49. PMID: 26141491.
      View in: PubMed
    20. Naasan G, Rabinovici GD, Ghosh P, Elofson JD, Miller BL, Coppola G, Karydas A, Fong J, Perry D, Lee SE, Yokoyama JS, Seeley WW, Kramer JH, Weiner MW, Schuff N, Jagust WJ, Grinberg LT, Pribadi M, Yang Z, Sears R, Klein E, Wojta K, Rosen HJ. Amyloid in dementia associated with familial FTLD: not an innocent bystander. Neurocase. 2016; 22(1):76-83. PMID: 26040468.
      View in: PubMed
    21. Perry DC, Sturm VE, Wood KA, Miller BL, Kramer JH. Divergent processing of monetary and social reward in behavioral variant frontotemporal dementia and Alzheimer disease. Alzheimer Dis Assoc Disord. 2015 Apr-Jun; 29(2):161-4. PMID: 24164741.
      View in: PubMed
    22. Liljegren M, Naasan G, Temlett J, Perry DC, Rankin KP, Merrilees J, Grinberg LT, Seeley WW, Englund E, Miller BL. Criminal behavior in frontotemporal dementia and Alzheimer disease. JAMA Neurol. 2015 Mar; 72(3):295-300. PMID: 25559744.
      View in: PubMed
    23. Perry DC, Sturm VE, Seeley WW, Miller BL, Kramer JH, Rosen HJ. Anatomical correlates of reward-seeking behaviours in behavioural variant frontotemporal dementia. Brain. 2014 Jun; 137(Pt 6):1621-6. PMID: 24740987.
      View in: PubMed
    24. Perry DC, Kramer JH. Reward processing in neurodegenerative disease. Neurocase. 2015 Feb; 21(1):120-33. PMID: 24417286.
      View in: PubMed
    25. Perry DC, Miller BL. Frontotemporal dementia. Semin Neurol. 2013 Sep; 33(4):336-41. PMID: 24234354.
      View in: PubMed
    26. Perry DC, Lehmann M, Yokoyama JS, Karydas A, Lee JJ, Coppola G, Grinberg LT, Geschwind D, Seeley WW, Miller BL, Rosen H, Rabinovici G. Progranulin mutations as risk factors for Alzheimer disease. JAMA Neurol. 2013 Jun; 70(6):774-8. PMID: 23609919.
      View in: PubMed
    27. Lamarre AK, Rascovsky K, Bostrom A, Toofanian P, Wilkins S, Sha SJ, Perry DC, Miller ZA, Naasan G, Laforce R, Hagen J, Takada LT, Tartaglia MC, Kang G, Galasko D, Salmon DP, Farias ST, Kaur B, Olichney JM, Quitania Park L, Mendez MF, Tsai PH, Teng E, Dickerson BC, Domoto-Reilly K, McGinnis S, Miller BL, Kramer JH. Interrater reliability of the new criteria for behavioral variant frontotemporal dementia. Neurology. 2013 May 21; 80(21):1973-7. PMID: 23635967.
      View in: PubMed
    28. Perry DC, Whitwell JL, Boeve BF, Pankratz VS, Knopman DS, Petersen RC, Jack CR, Josephs KA. Voxel-based morphometry in patients with obsessive-compulsive behaviors in behavioral variant frontotemporal dementia. Eur J Neurol. 2012 Jun; 19(6):911-7. PMID: 22284815.
      View in: PubMed
    29. Perry DC, Geschwind MD. Thorough work-up and new diagnostic criteria needed for CJD. Nat Rev Neurol. 2011 Sep 05; 7(9):479-80. PMID: 21892213.
      View in: PubMed