Matthias Behrends, MD

Title(s)Professor, Anesthesia
SchoolSchool of Medicine
Address521 Parnassus Avenue, #4307
San Francisco CA 94117
Phone415-514-3761
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    University of GÓ§ttingen1996
    University of Duisburg-EssenResidency2003Anesthesiology
    University of Duisburg-EssenFellowship2000Pathophysiology

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    Dr. Matthias Behrends is an anesthesiologist who joined UCSF in 2004. In his research, he focuses on optimizing treatment strategies in regional anesthesia (nerve blocks, or injections that numb pain in a certain part of the body).

    Behrends earned his medical degree from the University of G?ttingen. He trained in anesthesiology at the University of Duisburg-Essen. He also spent three years as a postdoctoral scholar in the pathophysiology department at the University of Duisburg-Essen, investigating myocardial hibernation and ischemic preconditioning.
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The Development and Implementation of the Fast-Pace Assessment Framework and Tiered Analgesic Orders for Opioid Optimization. Pain Manag Nurs. 2024 Mar 23. Bazinski M, Lau C, Clemons B, Purser L, Kangwankij A, Ngo L, Lang M, Besen B, Gross K, Borucki A, Behrends M, Miaskowski C, Schell-Chaple H. PMID: 38522974.
      View in: PubMed   Mentions:    Fields:    
    2. Measurements of pupillary unrest using infrared pupillometry fail to detect changes in pain intensity in patients after surgery: a prospective observational study. Can J Anaesth. 2024 Mar 19. Behrends M, Larson MD. PMID: 38504035.
      View in: PubMed   Mentions:    Fields:    
    3. Electronic health record intervention to increase use of NSAIDs as analgesia for hospitalised patients: a cluster randomised controlled study. BMJ Health Care Inform. 2023 Dec 30; 30(1). Bongiovanni T, Pletcher MJ, Robinson A, Lancaster E, Zhang L, Behrends M, Wick E, Auerbach A. PMID: 38159932; PMCID: PMC10759061.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Optimizing Uptake of Multimodal Pain Management After Surgery Using the Electronic Health Record. JAMA Surg. 2023 Oct 01; 158(10):1108-1111. Bongiovanni T, Lancaster E, Behrends M, Zhang L, Wick E, Auerbach A, Pletcher MJ. PMID: 37610736; PMCID: PMC10448375.
      View in: PubMed   Mentions:    Fields:    
    5. A behavioral intervention to promote use of multimodal pain medication for hospitalized patients: A randomized controlled trial. J Hosp Med. 2023 08; 18(8):685-692. Bongiovanni T, Pletcher MJ, Lau C, Robinson A, Lancaster E, Zhang L, Behrends M, Wick E, Auerbach A. PMID: 37357367; PMCID: PMC10578203.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Consensus guidelines for the perioperative management of patients undergoing endoscopic retrograde cholangiopancreatography. Br J Anaesth. 2023 06; 130(6):763-772. Azimaraghi O, Bilal M, Amornyotin S, Arain M, Behrends M, Berzin TM, Buxbaum JL, Choice C, Fassbender P, Sawhney MS, Sundar E, Wongtangman K, Leslie K, Eikermann M. PMID: 37062671.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Lidocaine Infusion for the Management of Postoperative Pain and Delirium (LIMPP): protocol for a randomised control trial. BMJ Open. 2022 06 06; 12(6):e059416. Buren MA, Theologis A, Zuraek A, Behrends M, Clark AJ, Leung JM. PMID: 35667730; PMCID: PMC9171272.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    8. Neuraxial and general anesthesia for outpatient total joint arthroplasty result in similarly low rates of major perioperative complications: a multicentered cohort study. Reg Anesth Pain Med. 2022 05; 47(5):294-300. Yap E, Wei J, Webb C, Ng K, Behrends M. PMID: 34992150; PMCID: PMC8961758.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. Extraplexus versus intraplexus ultrasound-guided interscalene brachial plexus block for ambulatory arthroscopic shoulder surgery: A randomized controlled trial. PLoS One. 2021; 16(2):e0246792. Harbell MW, Kolodzie K, Behrends M, Ma CB, Kinjo S, Yap E, Braehler MR, Aleshi P. PMID: 33600437; PMCID: PMC7891753.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    10. Editorial Commentary: Neuraxial Anesthesia Improves Pain After Hip Arthroscopy but Risks Ambulatory Discharge Delay. Arthroscopy. 2021 01; 37(1):147-148. Yap EN, Behrends M. PMID: 33384078.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Perioperative outcomes for patients on chronic buprenorphine undergoing spine surgery: A case series. J Opioid Manag. 2021; 17(7):171-177. Sharp AL, Gilbert S, Perez DN, Kolodzie K, Behrends M. PMID: 34520039.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Comparison of programmed intermittent epidural bolus and continuous epidural infusion for post-operative analgesia after major abdominal surgery: A randomized controlled trial. J Clin Anesth. 2020 Apr 28; 64:109850. Su PP, Peniche A, Clelland E, Ladd M, Delgado A, Chen LL, Siegmueller C, Latronica M, Naidu R, Aleshi P, Behrends M. PMID: 32361223.
      View in: PubMed   Mentions: 4     Fields:    
    13. International multicentre review of perioperative management and outcome for catecholamine-producing tumours. Br J Surg. 2020 01; 107(2):e170-e178. Groeben H, Walz MK, Nottebaum BJ, Alesina PF, Greenwald A, Schumann R, Hollmann MW, Schwarte L, Behrends M, Rössel T, Groeben C, Schäfer M, Lowery A, Hirata N, Yamakage M, Miller JA, Cherry TJ, Nelson A, Solorzano CC, Gigliotti B, Wang TS, Wietasch JKG, Friederich P, Sheppard B, Graham PH, Weingarten TN, Sprung J. PMID: 31903598; PMCID: PMC8046358.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    14. Acute Pain in Older Adults: Recommendations for Assessment and Treatment. Anesthesiol Clin. 2019 Sep; 37(3):507-520. Rajan J, Behrends M. PMID: 31337481.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    15. Preoperative Fascia Iliaca Block Does Not Improve Analgesia after Arthroscopic Hip Surgery, but Causes Quadriceps Muscles Weakness: A Randomized, Double-blind Trial. Anesthesiology. 2018 09; 129(3):536-543. Behrends M, Yap EN, Zhang AL, Kolodzie K, Kinjo S, Harbell MW, Aleshi P. PMID: 29975203.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    16. Suppression of pupillary unrest by general anesthesia and propofol sedation. J Clin Monit Comput. 2019 Apr; 33(2):317-323. Behrends M, Larson MD, Neice AE, Bokoch MP. PMID: 29785552.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    17. In Response. Anesth Analg. 2017 08; 125(2):694-695. Neice AE, Larson MD, Behrends M, Bokoch MP. PMID: 28632538.
      View in: PubMed   Mentions:    Fields:    
    18. Prediction of Opioid Analgesic Efficacy by Measurement of Pupillary Unrest. Anesth Analg. 2017 03; 124(3):915-921. Neice AE, Behrends M, Bokoch MP, Seligman KM, Conrad NM, Larson MD. PMID: 27941575.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    19. Combined preoperative femoral and sciatic nerve blockade improves analgesia after anterior cruciate ligament reconstruction: a randomized controlled clinical trial. J Clin Anesth. 2016 Sep; 33:68-74. Harbell MW, Cohen JM, Kolodzie K, Behrends M, Braehler MR, Kinjo S, Feeley BT, Aleshi P. PMID: 27555136.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    20. Portable infrared pupillometry: a review. Anesth Analg. 2015 Jun; 120(6):1242-53. Larson MD, Behrends M. PMID: 25988634.
      View in: PubMed   Mentions: 78     Fields:    Translation:Humans
    21. Blood Transfusion and Postoperative Delirium. Current Anesthesiology Reports. 2015 Mar 1; 5(1):24-32. Whitlock WE, Behrends BM. .
      View in: Publisher Site   Mentions:
    22. Fentanyl, an agonist at the mu opioid receptor, depresses pupillary unrest. Auton Neurosci. 2015 May; 189:68-74. Bokoch MP, Behrends M, Neice A, Larson MD. PMID: 25737234.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    23. Association between intraoperative blood transfusions and early postoperative delirium in older adults. J Am Geriatr Soc. 2013 Mar; 61(3):365-70. Behrends M, DePalma G, Sands L, Leung J. PMID: 23496244; PMCID: PMC4529289.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    24. Infrared pupillometry to detect the light reflex during cardiopulmonary resuscitation: a case series. Resuscitation. 2012 Oct; 83(10):1223-8. Behrends M, Niemann CU, Larson MD. PMID: 22659054.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    25. Induction of intestinal ischemia reperfusion injury by portal vein outflow occlusion in rats. J Gastroenterol. 2010 Nov; 45(11):1103-10. Vincenti M, Behrends M, Dang K, Park YH, Hirose R, Blasi-Ibanez A, Liu T, Serkova NJ, Niemann CU. PMID: 20549254.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    26. Short passive cooling protects rats during hepatectomy by inducing heat shock proteins and limiting the induction of pro-inflammatory cytokines. J Surg Res. 2010 Jan; 158(1):43-52. Niemann CU, Xu F, Choi S, Behrends M, Park Y, Hirose R, Maher JJ. PMID: 19394963; PMCID: PMC5725336.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    27. Acute hyperglycemia worsens hepatic ischemia/reperfusion injury in rats. J Gastrointest Surg. 2010 Mar; 14(3):528-35. Behrends M, Martinez-Palli G, Niemann CU, Cohen S, Ramachandran R, Hirose R. PMID: 19997981; PMCID: PMC2820661.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    28. Transient hyperglycemia affects the extent of ischemia-reperfusion-induced renal injury in rats. Anesthesiology. 2008 Mar; 108(3):402-14. Hirose R, Xu F, Dang K, Liu T, Behrends M, Brakeman PR, Wiener-Kronish J, Niemann CU. PMID: 18292678.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    29. Increased severity of renal ischemia-reperfusion injury with venous clamping compared to arterial clamping in a rat model. Surgery. 2008 Feb; 143(2):243-51. Park Y, Hirose R, Dang K, Xu F, Behrends M, Tan V, Roberts JP, Niemann CU. PMID: 18242341.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    30. Myocardial stunning following no flow ischaemia is diminished by levosimendan or cariporide, without benefits of combined administration. Resuscitation. 2008 Jan; 76(1):95-102. Brendt P, Behrends M, Peters J. PMID: 17719165.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    31. Remote renal injury following partial hepatic ischemia/reperfusion injury in rats. J Gastrointest Surg. 2008 Mar; 12(3):490-5. Behrends M, Hirose R, Park YH, Tan V, Dang K, Xu F, Park SH, Niemann CU. PMID: 17701074.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    32. Central venous pressure monitoring during living right donor hepatectomy. Liver Transpl. 2007 Feb; 13(2):266-71. Niemann CU, Feiner J, Behrends M, Eilers H, Ascher NL, Roberts JP. PMID: 17256757.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    33. Ischemia-reperfusion injury is more severe in older versus young rat livers. J Surg Res. 2007 Jan; 137(1):96-102. Park Y, Hirose R, Coatney JL, Ferrell L, Behrends M, Roberts JP, Serkova NJ, Niemann CU. PMID: 17064732.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    34. Mild hypothermia reduces the inflammatory response and hepatic ischemia/reperfusion injury in rats. Liver Int. 2006 Aug; 26(6):734-41. Behrends M, Hirose R, Serkova NJ, Coatney JL, Bedolli M, Yardi J, Park YH, Niemann CU. PMID: 16842331.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    35. Mild hypothermia protects obese rats from fulminant hepatic necrosis induced by ischemia-reperfusion. Surgery. 2006 Sep; 140(3):404-12. Niemann CU, Choi S, Behrends M, Hirose R, Noh J, Coatney JL, Roberts JP, Serkova NJ, Maher JJ. PMID: 16934602.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    36. Recombinant factor VIIa reduces transfusion requirements in liver transplant patients with high MELD scores. Transfus Med. 2006 Apr; 16(2):93-100. Niemann CU, Behrends M, Quan D, Eilers H, Gropper MA, Roberts JP, Hirose R. PMID: 16623915.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    37. Glutamine does not protect against hepatic warm ischemia/reperfusion injury in rats. J Gastrointest Surg. 2006 Feb; 10(2):234-9. Noh J, Behrends M, Choi S, Bedolli MA, Yardi J, Hirose R, Niemann CU. PMID: 16455456.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    38. Ischemic preconditioning improves energy state and transplantation survival in obese Zucker rat livers. Anesth Analg. 2005 Dec; 101(6):1577-1583. Niemann CU, Hirose R, Liu T, Behrends M, Brown JL, Kominsky DF, Roberts JP, Serkova N. PMID: 16301222.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    39. Acute lung injury after peppermint oil injection. Anesth Analg. 2005 Oct; 101(4):1160-1162. Behrends M, Beiderlinden M, Peters J. PMID: 16192538.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    40. Glutamine does not ameliorate hepatic ischemia/reperfusion injury in rats. Journal of Gastrointestinal Surgery. 2005 Apr 1; 9(4):555. Behrends BM, Noh NJ, Choi CS, Hirose HR, Bedoli BM, Roberts RJ, Niemann NC. .
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    41. Normothermia during partial hepatic ischemia increases hepatic injury. Journal of Gastrointestinal Surgery. 2005 Apr 1; 9(4):554-555. Behrends BM, Hirose HR, Choi CS, Niemann NC. .
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    42. Combination of sildenafil and bosentan for nitric oxide withdrawal. Eur J Anaesthesiol. 2005 Feb; 22(2):155-7. Behrends M, Beiderlinden M, Peters J. PMID: 15816597.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    43. The calcium sensitizer levosimendan attenuates endotoxin-evoked myocardial dysfunction in isolated guinea pig hearts. Intensive Care Med. 2003 Oct; 29(10):1802-7. Behrends M, Peters J. PMID: 12879240.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    44. Signal transduction of ischemic preconditioning. Cardiovasc Res. 2001 Nov; 52(2):181-98. Schulz R, Cohen MV, Behrends M, Downey JM, Heusch G. PMID: 11684066.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    45. Minimal protection of the liver by ischemic preconditioning in pigs. Am J Physiol Heart Circ Physiol. 2001 Jan; 280(1):H198-207. Schulz R, Walz MK, Behrends M, Neumann T, Gerken G, Heusch G. PMID: 11123234.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    46. In vitro validation of a metabolic monitor for gas exchange measurements in ventilated neonates. Intensive Care Med. 2001 Jan; 27(1):228-35. Behrends M, Kernbach M, Bräuer A, Braun U, Peters J, Weyland W. PMID: 11280640.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    47. Perfusion-contraction mismatch with coronary microvascular obstruction: role of inflammation. Am J Physiol Heart Circ Physiol. 2000 Dec; 279(6):H2587-92. Dörge H, Neumann T, Behrends M, Skyschally A, Schulz R, Kasper C, Erbel R, Heusch G. PMID: 11087208.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    48. No protection of the porcine kidney by ischaemic preconditioning. Exp Physiol. 2000 Nov; 85(6):819-27. Behrends M, Walz MK, Kribben A, Neumann T, Helmchen U, Philipp T, Schulz R, Heusch G. PMID: 11187976.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    49. Enhanced reduction of myocardial infarct size by combined ACE inhibition and AT(1)-receptor antagonism. Br J Pharmacol. 2000 Sep; 131(1):138-44. Weidenbach R, Schulz R, Gres P, Behrends M, Post H, Heusch G. PMID: 10960080; PMCID: PMC1572300.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    50. Inconsistent relation of MAPK activation to infarct size reduction by ischemic preconditioning in pigs. Am J Physiol Heart Circ Physiol. 2000 Sep; 279(3):H1111-9. Behrends M, Schulz R, Post H, Alexandrov A, Belosjorow S, Michel MC, Heusch G. PMID: 10993774.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    51. Intraperitoneal and retroperitoneal carbon dioxide insufflation evoke different effects on caval vein pressure gradients in humans: evidence for the starling resistor concept of abdominal venous return. Anesthesiology. 2000 Jun; 92(6):1568-80. Giebler RM, Behrends M, Steffens T, Walz MK, Peitgen K, Peters J. PMID: 10839905.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    52. No involvement of endogenous nitric oxide in classical ischemic preconditioning in swine. J Mol Cell Cardiol. 2000 May; 32(5):725-33. Post H, Schulz R, Behrends M, Gres P, Umschlag C, Heusch G. PMID: 10775478.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    53. Attenuation of myocardial stunning by the AT1 receptor antagonist candesartan. Basic Res Cardiol. 1999 Jun; 94(3):208-14. Dörge H, Behrends M, Schulz R, Jalowy A, Heusch G. PMID: 10424239.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    54. Effects of verapamil and mibefradil on regional blood flow and function in normal and ischemic myocardium. Cardiovasc Drugs Ther. 1999 May; 13(3):275-6. Behrends M, Schulz R, Heusch G. PMID: 10439892.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    55. Infarct size reduction by AT1-receptor blockade through a signal cascade of AT2-receptor activation, bradykinin and prostaglandins in pigs. J Am Coll Cardiol. 1998 Nov 15; 32(6):1787-96. Jalowy A, Schulz R, Dörge H, Behrends M, Heusch G. PMID: 9822110.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    56. Caval pressure gradients are induced with intraperitoneal but not with retroperitoneal CO2 insufflation during laparoscopic or retroperitoneoscopic surgical procedures in humans. Anesthesiology. 1998 Sep 1; 89(Supplement):284a. Giebler GR, Behrends BM, Walz WM, Peitgen PK, Peters PJ. .
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