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Ryutaro Hirose, MD

Title(s)Professor, Surgery
SchoolSchool of Medicine
Phone415-353-8783
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    University of California, San FranciscoResidency School of Medicine
    University of California, San Francisco, CA2019Diversity, Equity, and Inclusion Champion Training

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Bertsimas D, Papalexopoulos T, Trichakis N, Wang Y, Hirose R, Vagefi PA. Balancing efficiency and fairness in liver transplant access: tradeoff curves for the assessment of organ distribution policies. Transplantation. 2019 Oct 21. PMID: 31644494.
      View in: PubMed
    2. Roll GR, Webber AB, Gae DH, Laszik Z, Tavakol M, Mayen L, Cunniffe K, Syed S, Hirose R, Freise C, Feng S, Roberts JP, Ascher NL, Stock PG, Rajalingam R. A virtual crossmatch based strategy facilitates sharing of deceased donor kidneys for highly sensitized recipients. Transplantation. 2019 Aug 19. PMID: 31449187.
      View in: PubMed
    3. Parekh JR, Hirose R, Foley DP, Grieco A, Cohen ME, Hall BL, Ko CY, Greenstein S. Beyond death and graft survival-Variation in outcomes after kidney transplantation. Results from the NSQIP Transplant beta phase. Am J Transplant. 2019 Sep; 19(9):2622-2630. PMID: 30980484.
      View in: PubMed
    4. Cullaro G, Hirose R, Lai JC. Changes in Simultaneous Liver-kidney Transplant Allocation Policy May Impact Postliver Transplant Outcomes. Transplantation. 2019 May; 103(5):959-964. PMID: 30086097.
      View in: PubMed
    5. Parekh JR, Greenstein S, Sudan DL, Grieco A, Cohen ME, Hall BL, Ko CY, Hirose R. Beyond death and graft survival-Variation in outcomes after liver transplant. Results from the NSQIP transplant beta phase. Am J Transplant. 2019 Jul; 19(7):2108-2115. PMID: 30887634.
      View in: PubMed
    6. Mehta N, Dodge JL, Hirose R, Roberts JP, Yao FY. Predictors of low risk for dropout from the liver transplant waiting list for hepatocellular carcinoma in long wait time regions: Implications for organ allocation. Am J Transplant. 2019 Aug; 19(8):2210-2218. PMID: 30861298.
      View in: PubMed
    7. Hirose R. State-Based Liver Allocation: Is It a Viable Alternative? Liver Transpl. 2019 Apr; 25(4):535-537. PMID: 30861302.
      View in: PubMed
    8. Gao Y, Twigg AR, Hirose R, Roll GR, Nowacki AS, Maytin EV, Vidimos AT, Rajalingam R, Arron ST. Association of HLA Antigen Mismatch With Risk of Developing Skin Cancer After Solid-Organ Transplant. JAMA Dermatol. 2019 Mar 01; 155(3):307-314. PMID: 30673077.
      View in: PubMed
    9. Mehta N, Dodge JL, Roberts JP, Hirose R, Yao FY. Alpha-Fetoprotein Decrease from > 1,000 to < 500 ng/mL in Patients with Hepatocellular Carcinoma Leads to Improved Posttransplant Outcomes. Hepatology. 2019 Mar; 69(3):1193-1205. PMID: 30548884.
      View in: PubMed
    10. Bertsimas D, Kung J, Trichakis N, Wang Y, Hirose R, Vagefi PA. Development and validation of an optimized prediction of mortality for candidates awaiting liver transplantation. Am J Transplant. 2019 Apr; 19(4):1109-1118. PMID: 30411495.
      View in: PubMed
    11. Cooper M, Formica R, Friedewald J, Hirose R, O'Connor K, Mohan S, Schold J, Axelrod D, Pastan S. Report of National Kidney Foundation Consensus Conference to Decrease Kidney Discards. Clin Transplant. 2019 01; 33(1):e13419. PMID: 30345720.
      View in: PubMed
    12. Mehta N, Dodge JL, Hirose R, Roberts JP, Yao FY. Increasing Liver Transplantation Wait-List Dropout for Hepatocellular Carcinoma With Widening Geographical Disparities: Implications for Organ Allocation. Liver Transpl. 2018 10; 24(10):1346-1356. PMID: 30067889.
      View in: PubMed
    13. Patel MS, Hirose R, Vagefi PA. How Good Is Good? Benchmarking and the Quest for Quality Improvement in Liver Transplantation. Ann Surg. 2018 03; 267(3):426-427. PMID: 29319540.
      View in: PubMed
    14. Mehta N, Dodge JL, Roberts JP, Hirose R, Yao FY. Misdiagnosis of hepatocellular carcinoma in patients receiving no local-regional therapy prior to liver transplant: An analysis of the Organ Procurement and Transplantation Network explant pathology form. Clin Transplant. 2017 Nov; 31(11). PMID: 28881064.
      View in: PubMed
    15. Hirose R, Heimbach J. Defining disparities in liver transplantation: The devil is in the details. Liver Transpl. 2017 04; 23(4):557-558. PMID: 28160412.
      View in: PubMed
    16. Deshpande R, Hirose R, Mulligan D. Liver allocation and distribution: time for a change. Curr Opin Organ Transplant. 2017 Apr; 22(2):162-168. PMID: 28212159.
      View in: PubMed
    17. Hart A, Schladt DP, Zeglin J, Pyke J, Kim WR, Lake JR, Roberts JP, Hirose R, Mulligan DC, Kasiske BL, Snyder JJ, Israni AK. Predicting Outcomes on the Liver Transplant Waiting List in the United States: Accounting for Large Regional Variation in Organ Availability and Priority Allocation Points. Transplantation. 2016 10; 100(10):2153-9. PMID: 27490411.
      View in: PubMed
    18. Gentry SE, Hirose R, Mulligan D. Resolving Misconceptions About Liver Allocation and Redistricting Methodology. JAMA Surg. 2016 10 01; 151(10):991-992. PMID: 27333440.
      View in: PubMed
    19. Parekh J, Roll GR, Wisel S, Rushakoff RJ, Hirose R. Effect of moderately intense perioperative glucose control on renal allograft function: a pilot randomized controlled trial in renal transplantation. Clin Transplant. 2016 10; 30(10):1242-1249. PMID: 27423055.
      View in: PubMed
    20. Kim SS, Nakakura EK, Wang ZJ, Kim GE, Corvera CU, Harris HW, Kirkwood KS, Hirose R, Tempero MA, Ko AH. Preoperative FOLFIRINOX for borderline resectable pancreatic cancer: Is radiation necessary in the modern era of chemotherapy? J Surg Oncol. 2016 Oct; 114(5):587-596. PMID: 27444658.
      View in: PubMed
    21. Edwards EB, Harper AM, Hirose R, Mulligan DC. The impact of broader regional sharing of livers: 2-year results of "Share 35". Liver Transpl. 2016 Apr; 22(4):399-409. PMID: 26890858.
      View in: PubMed
    22. Mehta N, Heimbach J, Hirose R, Roberts JP, Yao FY. Minimal Transplant Survival Benefit for Hepatocellular Carcinoma: Is it Real or an Overestimation of Waitlist Life Expectancy? Gastroenterology. 2016 Feb; 150(2):533-4. PMID: 26718172.
      View in: PubMed
    23. Olmos A, Feiner J, Hirose R, Swain S, Blasi A, Roberts JP, Niemann CU. Impact of a quality improvement project on deceased organ donor management. Prog Transplant. 2015 Dec; 25(4):351-60. PMID: 26645930.
      View in: PubMed
    24. Gentry SE, Segev DL, Kasiske BL, Mulligan DC, Hirose R. Robust Models Support Redistricting Liver Allocation to Reduce Geographic Disparity. Transplantation. 2015 Sep; 99(9):e159-60. PMID: 26308421.
      View in: PubMed
    25. Niemann CU, Feiner J, Swain S, Bunting S, Friedman M, Crutchfield M, Broglio K, Hirose R, Roberts JP, Malinoski D. Therapeutic Hypothermia in Deceased Organ Donors and Kidney-Graft Function. N Engl J Med. 2015 Jul 30; 373(5):405-14. PMID: 26222557.
      View in: PubMed
    26. Yao FY, Mehta N, Flemming J, Dodge J, Hameed B, Fix O, Hirose R, Fidelman N, Kerlan RK, Roberts JP. Downstaging of hepatocellular cancer before liver transplant: long-term outcome compared to tumors within Milan criteria. Hepatology. 2015 Jun; 61(6):1968-77. PMID: 25689978.
      View in: PubMed
    27. Heimbach JK, Hirose R, Stock PG, Schladt DP, Xiong H, Liu J, Olthoff KM, Harper A, Snyder JJ, Israni AK, Kasiske BL, Kim WR. Delayed hepatocellular carcinoma model for end-stage liver disease exception score improves disparity in access to liver transplant in the United States. Hepatology. 2015 May; 61(5):1643-50. PMID: 25644186.
      View in: PubMed
    28. Mehta N, Dodge JL, Roberts JP, Hirose R, Yao FY. Outcomes after liver transplantation for patients with hepatocellular carcinoma and a low risk of dropout from the transplant waiting list. Liver Transpl. 2014 May; 20(5):627-8. PMID: 24493311.
      View in: PubMed
    29. Mehta N, Dodge JL, Goel A, Roberts JP, Hirose R, Yao FY. Identification of liver transplant candidates with hepatocellular carcinoma and a very low dropout risk: implications for the current organ allocation policy. Liver Transpl. 2013 Dec; 19(12):1343-53. PMID: 24285611.
      View in: PubMed
    30. Mehta N, Hirose R. Immunosuppression: Conventions and controversies. Clin Liver Dis (Hoboken). 2013 Aug; 2(4):188-191. PMID: 30992859.
      View in: PubMed
    31. Parekh J, Roll GR, Feng S, Niemann CU, Hirose R. Peri-operative hyperglycemia is associated with delayed graft function in deceased donor renal transplantation. Clin Transplant. 2013 Jul-Aug; 27(4):E424-30. PMID: 23808826.
      View in: PubMed
    32. Vagefi PA, Hirose R. Sorafenib combined with locoregional therapy prior to liver transplantation for hepatocellular carcinoma: an update on a previous case report. J Gastrointest Cancer. 2013 Jun; 44(2):246-7. PMID: 22815137.
      View in: PubMed
    33. Mandell MS, Pomfret EA, Steadman R, Hirose R, Reich DJ, Schumann R, Walia A. Director of anesthesiology for liver transplantation: existing practices and recommendations by the United Network for Organ Sharing. Liver Transpl. 2013 Apr; 19(4):425-30. PMID: 23447113.
      View in: PubMed
    34. Vagefi PA, Qian JJ, Carlson DM, Aparici CM, Hirose R, Vincenti F, Wojciechowski D. Native renal function after combined liver-kidney transplant for type 1 hepatorenal syndrome: initial report on the use of postoperative Technetium-99 m-mercaptoacetyltriglycine scans. Transpl Int. 2013 May; 26(5):471-6. PMID: 23384317.
      View in: PubMed
    35. Gogia R, Binstock M, Hirose R, Boscardin WJ, Chren MM, Arron ST. Fitzpatrick skin phototype is an independent predictor of squamous cell carcinoma risk after solid organ transplantation. J Am Acad Dermatol. 2013 Apr; 68(4):585-591. PMID: 23107311.
      View in: PubMed
    36. Park SJ, Freise CE, Hirose R, Kerlan RK, Yao FY, Roberts JP, Vagefi PA. Risk factors for liver transplant waitlist dropout in patients with hepatocellular carcinoma. Clin Transplant. 2012 Jul-Aug; 26(4):E359-64. PMID: 22693962.
      View in: PubMed
    37. Kelley RK, Hirose R, Venook AP. Can we cure cholangiocarcinoma with neoadjuvant chemoradiation and liver transplantation? Time for a multicenter trial. Liver Transpl. 2012 May; 18(5):509-13. PMID: 22389236.
      View in: PubMed
    38. Dybbro E, Mihalis E, Hirose R, Arron ST. Validity of patient skin cancer report among organ transplant recipients. Clin Transplant. 2012 Mar-Apr; 26(2):E132-6. PMID: 22428900.
      View in: PubMed
    39. Parekh J, Niemann CU, Dang K, Hirose R. Intraoperative hyperglycemia augments ischemia reperfusion injury in renal transplantation: a prospective study. J Transplant. 2011; 2011:652458. PMID: 21904663.
      View in: PubMed
    40. Vu LT, Baxter-Lowe LA, Garcia J, McEnhill M, Summers P, Hirose R, Lee M, Stock PG. HLA-DR matching in organ allocation: balance between waiting time and rejection in pediatric kidney transplantation. Arch Surg. 2011 Jul; 146(7):824-9. PMID: 21768429.
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    41. Webber A, Hirose R, Vincenti F. Novel strategies in immunosuppression: issues in perspective. Transplantation. 2011 May 27; 91(10):1057-64. PMID: 21412186.
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    42. Vagefi PA, Hirose R. Downstaging of hepatocellular carcinoma prior to liver transplant: is there a role for adjuvant sorafenib in locoregional therapy? J Gastrointest Cancer. 2010 Dec; 41(4):217-20. PMID: 20443078.
      View in: PubMed
    43. Martinez-Palli G, Hirose R, Liu T, Xu F, Dang K, Feiner J, Serkova NJ, Niemann CU. Donor pre-treatment with everolimus or cyclosporine does not reduce ischaemia-reperfusion injury in a rat kidney transplant model. Nephrol Dial Transplant. 2011 Jun; 26(6):1813-20. PMID: 21068143.
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    44. Alemi F, Kwon E, Freise C, Kang SM, Hirose R, Stewart L, Corvera CU. Hepatic surgery at a VA tertiary medical center: lessons learned. Am J Surg. 2010 Nov; 200(5):591-5. PMID: 21056134.
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    45. Vincenti M, Behrends M, Dang K, Park YH, Hirose R, Blasi-Ibanez A, Liu T, Serkova NJ, Niemann CU. Induction of intestinal ischemia reperfusion injury by portal vein outflow occlusion in rats. J Gastroenterol. 2010 Nov; 45(11):1103-10. PMID: 20549254.
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    46. Niemann CU, Xu F, Choi S, Behrends M, Park Y, Hirose R, Maher JJ. Short passive cooling protects rats during hepatectomy by inducing heat shock proteins and limiting the induction of pro-inflammatory cytokines. J Surg Res. 2010 Jan; 158(1):43-52. PMID: 19394963.
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    47. Wojciechowski D, Hirose R, Stock P, Vincenti F, Baxter-Lowe LA, Salvatierra O. Kidney transplantation at UCSF: 8,300 transplants and onward. Clin Transpl. 2010; 161-7. PMID: 21696039.
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    48. Behrends M, Martinez-Palli G, Niemann CU, Cohen S, Ramachandran R, Hirose R. Acute hyperglycemia worsens hepatic ischemia/reperfusion injury in rats. J Gastrointest Surg. 2010 Mar; 14(3):528-35. PMID: 19997981.
      View in: PubMed
    49. Niemann CU, Walia A, Waldman J, Davio M, Roberts JP, Hirose R, Feiner J. Acute kidney injury during liver transplantation as determined by neutrophil gelatinase-associated lipocalin. Liver Transpl. 2009 Dec; 15(12):1852-60. PMID: 19938135.
      View in: PubMed
    50. Blasi-Ibanez A, Hirose R, Feiner J, Freise C, Stock PG, Roberts JP, Niemann CU. Predictors associated with terminal renal function in deceased organ donors in the intensive care unit. Anesthesiology. 2009 Feb; 110(2):333-41. PMID: 19194160.
      View in: PubMed
    51. Yao FY, Kerlan RK, Hirose R, Davern TJ, Bass NM, Feng S, Peters M, Terrault N, Freise CE, Ascher NL, Roberts JP. Excellent outcome following down-staging of hepatocellular carcinoma prior to liver transplantation: an intention-to-treat analysis. Hepatology. 2008 Sep; 48(3):819-27. PMID: 18688876.
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    52. Hirsch J, Niemann CU, Hansen KC, Choi S, Su X, Frank JA, Fang X, Hirose R, Theodore P, Sapru A, Burlingame AL, Matthay MA. Alterations in the proteome of pulmonary alveolar type II cells in the rat after hepatic ischemia-reperfusion. Crit Care Med. 2008 Jun; 36(6):1846-54. PMID: 18496381.
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    53. Hirose R, Xu F, Dang K, Liu T, Behrends M, Brakeman PR, Wiener-Kronish J, Niemann CU. Transient hyperglycemia affects the extent of ischemia-reperfusion-induced renal injury in rats. Anesthesiology. 2008 Mar; 108(3):402-14. PMID: 18292678.
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    54. Hirose R, Yao F, Stock P, Roberts J, Ascher N. Liver transplantation at UCSF--a 20-year experience. Clin Transpl. 2008; 119-25. PMID: 19708450.
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    55. Park Y, Hirose R, Dang K, Xu F, Behrends M, Tan V, Roberts JP, Niemann CU. Increased severity of renal ischemia-reperfusion injury with venous clamping compared to arterial clamping in a rat model. Surgery. 2008 Feb; 143(2):243-51. PMID: 18242341.
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    56. Behrends M, Hirose R, Park YH, Tan V, Dang K, Xu F, Park SH, Niemann CU. Remote renal injury following partial hepatic ischemia/reperfusion injury in rats. J Gastrointest Surg. 2008 Mar; 12(3):490-5. PMID: 17701074.
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    57. Park Y, Hirose R, Coatney JL, Ferrell L, Behrends M, Roberts JP, Serkova NJ, Niemann CU. Ischemia-reperfusion injury is more severe in older versus young rat livers. J Surg Res. 2007 Jan; 137(1):96-102. PMID: 17064732.
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    58. Behrends M, Hirose R, Serkova NJ, Coatney JL, Bedolli M, Yardi J, Park YH, Niemann CU. Mild hypothermia reduces the inflammatory response and hepatic ischemia/reperfusion injury in rats. Liver Int. 2006 Aug; 26(6):734-41. PMID: 16842331.
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    59. Hirose R, Vincenti F. Immunosuppression: today, tomorrow, and withdrawal. Semin Liver Dis. 2006 Aug; 26(3):201-10. PMID: 16850369.
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    60. Niemann CU, Choi S, Behrends M, Hirose R, Noh J, Coatney JL, Roberts JP, Serkova NJ, Maher JJ. Mild hypothermia protects obese rats from fulminant hepatic necrosis induced by ischemia-reperfusion. Surgery. 2006 Sep; 140(3):404-12. PMID: 16934602.
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    61. Hirsch J, Hansen KC, Choi S, Noh J, Hirose R, Roberts JP, Matthay MA, Burlingame AL, Maher JJ, Niemann CU. Warm ischemia-induced alterations in oxidative and inflammatory proteins in hepatic Kupffer cells in rats. Mol Cell Proteomics. 2006 Jun; 5(6):979-86. PMID: 16500929.
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    62. Noh J, Behrends M, Choi S, Bedolli MA, Yardi J, Hirose R, Niemann CU. Glutamine does not protect against hepatic warm ischemia/reperfusion injury in rats. J Gastrointest Surg. 2006 Feb; 10(2):234-9. PMID: 16455456.
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    63. Niemann CU, Hirose R, Liu T, Behrends M, Brown JL, Kominsky DF, Roberts JP, Serkova N. Ischemic preconditioning improves energy state and transplantation survival in obese Zucker rat livers. Anesth Analg. 2005 Dec; 101(6):1577-83. PMID: 16301222.
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    64. Yao FY, Hirose R, LaBerge JM, Davern TJ, Bass NM, Kerlan RK, Merriman R, Feng S, Freise CE, Ascher NL, Roberts JP. A prospective study on downstaging of hepatocellular carcinoma prior to liver transplantation. Liver Transpl. 2005 Dec; 11(12):1505-14. PMID: 16315294.
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    65. Aziz S, Callen PW, Vincenti F, Hirose R. Rapidly developing nephrocalcinosis in a patient with end-stage liver disease who received a domino liver transplant from a patient with known congenital oxalosis. J Ultrasound Med. 2005 Oct; 24(10):1449-52. PMID: 16179633.
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    66. Otley CC, Hirose R, Salasche SJ. Skin cancer as a contraindication to organ transplantation. Am J Transplant. 2005 Sep; 5(9):2079-84. PMID: 16095486.
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    67. Serkova NJ, Jackman M, Brown JL, Liu T, Hirose R, Roberts JP, Maher JJ, Niemann CU. Metabolic profiling of livers and blood from obese Zucker rats. J Hepatol. 2006 May; 44(5):956-62. PMID: 16223541.
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    68. Choi S, Noh J, Hirose R, Ferell L, Bedolli M, Roberts JP, Niemann CU. Mild hypothermia provides significant protection against ischemia/reperfusion injury in livers of obese and lean rats. Ann Surg. 2005 Mar; 241(3):470-6. PMID: 15729070.
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    69. Lipshutz GS, Mahanty H, Feng S, Hirose R, Stock PG, Kang SM, Posselt AM, Freise CE. BKV in simultaneous pancreas-kidney transplant recipients: a leading cause of renal graft loss in first 2 years post-transplant. Am J Transplant. 2005 Feb; 5(2):366-73. PMID: 15643997.
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    70. Visser BC, Suh I, Hirose S, Rosenthal P, Lee H, Roberts JP, Hirose R. The influence of portoenterostomy on transplantation for biliary atresia. Liver Transpl. 2004 Oct; 10(10):1279-86. PMID: 15376306.
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    71. Master VA, Meng MV, Grossfeld GD, Koppie TM, Hirose R, Carroll PR. Treatment and outcome of invasive bladder cancer in patients after renal transplantation. J Urol. 2004 Mar; 171(3):1085-8. PMID: 14767276.
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    72. Hiramoto JS, Tsung K, Bedolli M, Norton JA, Hirose R. Antitumor immunity induced by dendritic cell-based vaccination is dependent on interferon-gamma and interleukin-12. J Surg Res. 2004 Jan; 116(1):64-9. PMID: 14732350.
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    73. Yao FY, Saab S, Bass NM, Hirose R, Ly D, Terrault N, Lazar AA, Bacchetti P, Ascher NL, Roberts JP. Prediction of survival after liver retransplantation for late graft failure based on preoperative prognostic scores. Hepatology. 2004 Jan; 39(1):230-8. PMID: 14752842.
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    74. Stock PG, Roland ME, Carlson L, Freise CE, Roberts JP, Hirose R, Terrault NA, Frassetto LA, Palefsky JM, Tomlanovich SJ, Ascher NL. Kidney and liver transplantation in human immunodeficiency virus-infected patients: a pilot safety and efficacy study. Transplantation. 2003 Jul 27; 76(2):370-5. PMID: 12883195.
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    75. Posselt AM, Vincenti F, Bedolli M, Lantz M, Roberts JP, Hirose R. CD69 expression on peripheral CD8 T cells correlates with acute rejection in renal transplant recipients. Transplantation. 2003 Jul 15; 76(1):190-5. PMID: 12865808.
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    76. Fuller TF, Kang SM, Hirose R, Feng S, Stock PG, Freise CE. Management of lymphoceles after renal transplantation: laparoscopic versus open drainage. J Urol. 2003 Jun; 169(6):2022-5. PMID: 12771709.
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    77. Hiramoto JS, Freise CE, Randall HR, Bretan PN, Tomlanovich S, Stock PG, Hirose R. Successful long-term outcomes using pediatric en bloc kidneys for transplantation. Am J Transplant. 2002 Apr; 2(4):337-42. PMID: 12118855.
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    78. Hiramoto JS, LaBerge JM, Neymark E, Hirose R. Live donor renal transplants using kidneys with arteriographic evidence of mild renovascular disease. Clin Transplant. 2002 Feb; 16(1):24-9. PMID: 11982611.
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    79. Hirose R. Pros and cons of using interleukin-2 receptor antibodies in liver transplant recipients. Liver Transpl. 2002 Feb; 8(2):143-5. PMID: 11862590.
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