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Claus Niemann, MD

Title(s)Professor, Anesthesia
SchoolSchool of Medicine
Phone415-502-2162
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    My group is interested in identifying why obese individuals are at greater risk of liver injury in the setting of trauma or surgery. My long-term goal is to understand the relationship between metabolic and immunologic processes in the liver. One potential link between these underlying mechanisms could be the peptide leptin, which can profoundly modify inflammatory and metabolic pathways. The goal of this research effort is to improve understanding of the impact of leptin on acute inflammatory cascade and metabolic response during hepatic ischemia-reperfusion. This will benefit patients by improving risk-stratification of candidates for hepatic surgery and possibly lead to preventive therapies for ischemia-reperfusion injury.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation. Nat Commun. 2020 08 27; 11(1):4289. Iske J, Seyda M, Heinbokel T, Maenosono R, Minami K, Nian Y, Quante M, Falk CS, Azuma H, Martin F, Passos JF, Niemann CU, Tchkonia T, Kirkland JL, Elkhal A, Tullius SG. PMID: 32855397.
      View in: PubMed   Mentions:    Fields:    
    2. COVID-19 and Abdominal Transplant: A Stepwise Approach to Practice During Pandemic Conditions. Transplantation. 2020 Jun 29. Syed SM, Gardner J, Roll G, Webber A, Mehta N, Shoji J, Adelmann D, Niemann C, Braun HJ, Mello A, Yao F, Posselt A, Kang SM, Hirose R, Roberts J, Feng S, Ascher N, Stock P, Freise C. PMID: 32639408.
      View in: PubMed   Mentions:    Fields:    
    3. Impact of Deceased Donor Management on Donor Heart Use and Recipient Graft Survival. J Am Coll Surg. 2020 Sep; 231(3):351-360.e5. Swanson EA, Adams T, Patel MS, De La Cruz S, Hutchens M, Khush K, Sally MB, Niemann CU, Groat T, Malinoski DJ. PMID: 32562768.
      View in: PubMed   Mentions:    Fields:    
    4. Bacchus Listed for a Liver Transplant: Comment. Anesthesiology. 2020 06; 132(6):1594. Niemann CU. PMID: 32217873.
      View in: PubMed   Mentions:    Fields:    
    5. Vasopressor selection during critical care management of brain dead organ donors and the effects on kidney graft function. J Trauma Acute Care Surg. 2020 Jun; 88(6):783-788. Swanson EA, Patel MS, Groat T, Jameson NE, Ellis MKM, Hutchens MP, Niemann CU, Malinoski DJ, Sally MB. PMID: 32459446.
      View in: PubMed   Mentions:    Fields:    
    6. The Association Between Vena Cava Implantation Technique and Acute Kidney Injury After Liver Transplantation. Transplantation. 2020 May 25. Hannon V, Kothari RP, Zhang L, Bokoch MP, Hill R, Roll GR, Mello A, Feiner JR, Liu KD, Niemann CU, Adelmann D. PMID: 32467477.
      View in: PubMed   Mentions:    Fields:    
    7. The role of deceased donor liver biopsy: An analysis of 5449 liver transplant recipients. Clin Transplant. 2020 May; 34(5):e13835. Patel MS, Mohebali J, Coe TM, Sally M, Groat T, Niemann CU, Malinoski DJ, Vagefi PA. PMID: 32068301.
      View in: PubMed   Mentions:    Fields:    
    8. Transplant anesthesia and critical care: Current research and possible future developments. Best Pract Res Clin Anaesthesiol. 2020 Mar; 34(1):1-2. Niemann CU, Biancofiore G. PMID: 32334779.
      View in: PubMed   Mentions:    Fields:    
    9. Therapeutic Hypothermia in Organ Donors: Follow-up and Safety Analysis. Transplantation. 2019 11; 103(11):e365-e368. Malinoski D, Patel MS, Axelrod DA, Broglio K, Lewis RJ, Groat T, Niemann CU. PMID: 31356580.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Modeling the economic benefit of targeted mild hypothermia in deceased donor kidney transplantation. Clin Transplant. 2019 07; 33(7):e13626. Axelrod DA, Malinoski D, Patel MS, Broglio K, Lewis R, Groat T, Lentine KL, Schnitzler M, Niemann CU. PMID: 31162858.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. The Continued Need for Clinical Trials in Deceased Organ Donor Management. Transplantation. 2019 07; 103(7):1298-1299. Niemann CU, Matthay MA, Ware LB. PMID: 30399123.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Deceased organ donor factors influencing pancreatic graft transplantation and survival. Clin Transplant. 2019 06; 33(6):e13571. Sally MB, Ellis MK, Hutchens M, Groat T, Swanson E, Patel MS, Niemann CU, Malinoski DJ. PMID: 31001850.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. The Impact of Deceased Donor Liver Extraction Time on Early Allograft Function in Adult Liver Transplant Recipients. Transplantation. 2018 Nov; 102(11):e466-e471. Adelmann D, Roll GR, Kothari R, Syed S, Burdine LJ, Tavakol M, Niemann CU. PMID: 30048397.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Intraoperative Management of Liver Transplant Patients Without the Routine Use of Renal Replacement Therapy. Transplantation. 2018 05; 102(5):e229-e235. Adelmann D, Olmos A, Liu LL, Feiner JR, Roll GR, Burdine L, Tavakol M, Syed S, Orandi BJ, Niemann CU. PMID: 29470352.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Central venous pressure monitoring in living donor kidney recipients does not affect immediate graft function: A propensity score analysis. Clin Transplant. 2018 05; 32(5):e13238. Adelmann D, Bicknell L, Niemann CU, Feiner J, Roll GR, Burdine L, Whitlock EL. PMID: 29526051.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Organ Donor Management: Part 1. Toward a Consensus to Guide Anesthesia Services During Donation After Brain Death. Semin Cardiothorac Vasc Anesth. 2018 Jun; 22(2):211-222. Souter MJ, Eidbo E, Findlay JY, Lebovitz DJ, Moguilevitch M, Neidlinger NA, Wagener G, Paramesh AS, Niemann CU, Roberts PR, Pretto EA. PMID: 29276852.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Comments on "Impact of spontaneous donor hypothermia on graft outcomes after kidney transplantation". Am J Transplant. 2018 03; 18(3):763. Niemann CU, Broglio K, Malinoski D. PMID: 29139622.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Potentially inappropriate liver transplantation in the era of the "sickest first" policy - A search for the upper limits. J Hepatol. 2018 04; 68(4):798-813. Linecker M, Krones T, Berg T, Niemann CU, Steadman RH, Dutkowski P, Clavien PA, Busuttil RW, Truog RD, Petrowsky H. PMID: 29133246.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    19. Protecting the Kidney in Liver Transplant Recipients: Practice-Based Recommendations From the American Society of Transplantation Liver and Intestine Community of Practice. Am J Transplant. 2016 09; 16(9):2532-44. Levitsky J, O'Leary JG, Asrani S, Sharma P, Fung J, Wiseman A, Niemann CU. PMID: 26932352.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    20. Therapeutic Hypothermia in Deceased Organ Donors and Kidney-Graft Function. N Engl J Med. 2015 12 31; 373(27):2687. Niemann CU, Malinoski D. PMID: 26716922.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    21. Impact of a quality improvement project on deceased organ donor management. Prog Transplant. 2015 Dec; 25(4):351-60. Olmos A, Feiner J, Hirose R, Swain S, Blasi A, Roberts JP, Niemann CU. PMID: 26645930.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Therapeutic Hypothermia in Deceased Organ Donors and Kidney-Graft Function. N Engl J Med. 2015 Jul 30; 373(5):405-14. Niemann CU, Feiner J, Swain S, Bunting S, Friedman M, Crutchfield M, Broglio K, Hirose R, Roberts JP, Malinoski D. PMID: 26222557.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    23. Management of the Potential Organ Donor in the ICU: Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Consensus Statement. Crit Care Med. 2015 Jun; 43(6):1291-325. Kotloff RM, Blosser S, Fulda GJ, Malinoski D, Ahya VN, Angel L, Byrnes MC, DeVita MA, Grissom TE, Halpern SD, Nakagawa TA, Stock PG, Sudan DL, Wood KE, Anillo SJ, Bleck TP, Eidbo EE, Fowler RA, Glazier AK, Gries C, Hasz R, Herr D, Khan A, Landsberg D, Lebovitz DJ, Levine DJ, Mathur M, Naik P, Niemann CU, Nunley DR, O'Connor KJ, Pelletier SJ, Rahman O, Ranjan D, Salim A, Sawyer RG, Shafer T, Sonneti D, Spiro P, Valapour M, Vikraman-Sushama D, Whelan TP. PMID: 25978154.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    24. The Impact of Hydroxyethyl Starch Use in Deceased Organ Donors on the Development of Delayed Graft Function in Kidney Transplant Recipients: A Propensity-Adjusted Analysis. Am J Transplant. 2015 Aug; 15(8):2152-8. Patel MS, Niemann CU, Sally MB, De La Cruz S, Zatarain J, Ewing T, Crutchfield M, Enestvedt CK, Malinoski DJ. PMID: 25904248.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    25. A role for Rac1 activity in malignant progression of sebaceous skin tumors. Oncogene. 2015 Oct; 34(43):5505-12. Frances D, Sharma N, Pofahl R, Maneck M, Behrendt K, Reuter K, Krieg T, Klein CA, Haase I, Niemann C. PMID: 25659584.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    26. Abdominal transplantation. Anesthesiol Clin. 2013 Dec; 31(4):ix-x. Niemann CU. PMID: 24287352.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Patients with chronic kidney disease. Med Clin North Am. 2013 Nov; 97(6):1109-22. Kalamas AG, Niemann CU. PMID: 24182722.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    28. Peri-operative hyperglycemia is associated with delayed graft function in deceased donor renal transplantation. Clin Transplant. 2013 Jul-Aug; 27(4):E424-30. Parekh J, Roll GR, Feng S, Niemann CU, Hirose R. PMID: 23808826.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    29. Functional elements associated with hepatic regeneration in living donors after right hepatic lobectomy. Liver Transpl. 2013 Mar; 19(3):292-304. Everson GT, Hoefs JC, Niemann CU, Olthoff KM, Dupuis R, Lauriski S, Herman A, Milne N, Gillespie BW, Goodrich NP, Everhart JE. PMID: 23239552.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    30. Deceased organ donor research: the last research frontier? Liver Transpl. 2013 Feb; 19(2):118-21. Mone T, Heldens J, Niemann CU. PMID: 23193057.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    31. Liver transplantation outcome in patients with angiographically proven coronary artery disease: a multi-institutional study. Am J Transplant. 2013 Jan; 13(1):184-91. Wray C, Scovotti JC, Tobis J, Niemann CU, Planinsic R, Walia A, Findlay J, Wagener G, Cywinski JB, Markovic D, Hughes C, Humar A, Olmos A, Sierra R, Busuttil R, Steadman RH. PMID: 23126562.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    32. Infrared pupillometry to detect the light reflex during cardiopulmonary resuscitation: a case series. Resuscitation. 2012 Oct; 83(10):1223-8. Behrends M, Niemann CU, Larson MD. PMID: 22659054.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    33. Optimizing cost-effectiveness in perioperative care for liver transplantation: a model for low- to medium-income countries. Liver Transpl. 2011 Nov; 17(11):1247-78. Rando K, Niemann CU, Taura P, Klinck J. PMID: 21837742.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    34. Intraoperative hyperglycemia augments ischemia reperfusion injury in renal transplantation: a prospective study. J Transplant. 2011; 2011:652458. Parekh J, Niemann CU, Dang K, Hirose R. PMID: 21904663.
      View in: PubMed   Mentions:
    35. Transplant critical care: standards for intensive care of the patient with liver failure before and after transplantation. Liver Transpl. 2011 May; 17(5):485-7. Niemann CU, Kramer DJ. PMID: 21384522.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Intraoperative management of liver transplant patients. Transplant Rev (Orlando). 2011 Jul; 25(3):124-9. Liu LL, Niemann CU. PMID: 21514137.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    37. Donor pre-treatment with everolimus or cyclosporine does not reduce ischaemia-reperfusion injury in a rat kidney transplant model. Nephrol Dial Transplant. 2011 Jun; 26(6):1813-20. Martinez-Palli G, Hirose R, Liu T, Xu F, Dang K, Feiner J, Serkova NJ, Niemann CU. PMID: 21068143.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    38. Multivessel coronary artery disease predicts mortality, length of stay, and pressor requirements after liver transplantation. Liver Transpl. 2010 Nov; 16(11):1242-8. Yong CM, Sharma M, Ochoa V, Abnousi F, Roberts J, Bass NM, Niemann CU, Shiboski S, Prasad M, Tavakol M, Ports TA, Gregoratos G, Yeghiazarians Y, Boyle AJ. PMID: 21031539.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    39. Liver transplant perioperative pathways: which way towards high-quality care and better outcomes? Minerva Anestesiol. 2010 Oct; 76(10):769-70. Biancofiore G, Niemann CU. PMID: 20935608.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    40. 1H-NMR-based metabolic signatures of clinical outcomes in trauma patients--beyond lactate and base deficit. J Trauma. 2010 Jul; 69(1):31-40. Cohen MJ, Serkova NJ, Wiener-Kronish J, Pittet JF, Niemann CU. PMID: 20622576.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    41. Chronic kidney disease: implications for the perioperative period. Minerva Anestesiol. 2010 Sep; 76(9):725-36. Eilers H, Liu KD, Gruber A, Niemann CU. PMID: 20820151.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    42. Induction of intestinal ischemia reperfusion injury by portal vein outflow occlusion in rats. J Gastroenterol. 2010 Nov; 45(11):1103-10. Vincenti M, Behrends M, Dang K, Park YH, Hirose R, Blasi-Ibanez A, Liu T, Serkova NJ, Niemann CU. PMID: 20549254.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    43. Quality improvement in transplant anesthesia: which way forward? Curr Opin Organ Transplant. 2010 Jun; 15(3):374-6. Niemann CU, Feiner J. PMID: 20448487.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    44. Short passive cooling protects rats during hepatectomy by inducing heat shock proteins and limiting the induction of pro-inflammatory cytokines. J Surg Res. 2010 Jan; 158(1):43-52. Niemann CU, Xu F, Choi S, Behrends M, Park Y, Hirose R, Maher JJ. PMID: 19394963.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    45. Acute hyperglycemia worsens hepatic ischemia/reperfusion injury in rats. J Gastrointest Surg. 2010 Mar; 14(3):528-35. Behrends M, Martinez-Palli G, Niemann CU, Cohen S, Ramachandran R, Hirose R. PMID: 19997981.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    46. Acute kidney injury during liver transplantation as determined by neutrophil gelatinase-associated lipocalin. Liver Transpl. 2009 Dec; 15(12):1852-60. Niemann CU, Walia A, Waldman J, Davio M, Roberts JP, Hirose R, Feiner J. PMID: 19938135.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    47. Abdominal organ transplantation. Minerva Anestesiol. 2010 Apr; 76(4):266-75. Niemann CU, Eilers H. PMID: 20332740.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    48. Systemic inflammation, coagulopathy, and acute renal insufficiency following endovascular thoracoabdominal aortic aneurysm repair. J Vasc Surg. 2009 May; 49(5):1140-6. Chang CK, Chuter TA, Niemann CU, Shlipak MG, Cohen MJ, Reilly LM, Hiramoto JS. PMID: 19394543.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    49. Predictors associated with terminal renal function in deceased organ donors in the intensive care unit. Anesthesiology. 2009 Feb; 110(2):333-41. Blasi-Ibanez A, Hirose R, Feiner J, Freise C, Stock PG, Roberts JP, Niemann CU. PMID: 19194160.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    50. Postoperative infectious complications of abdominal solid organ transplantation. J Intensive Care Med. 2009 Jan-Feb; 24(1):3-17. Hlava N, Niemann CU, Gropper MA, Melcher ML. PMID: 19017663.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    51. Alterations in the proteome of pulmonary alveolar type II cells in the rat after hepatic ischemia-reperfusion. Crit Care Med. 2008 Jun; 36(6):1846-54. Hirsch J, Niemann CU, Hansen KC, Choi S, Su X, Frank JA, Fang X, Hirose R, Theodore P, Sapru A, Burlingame AL, Matthay MA. PMID: 18496381.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    52. Perioperative liver transplant best practices: weighing the evidence. Curr Opin Organ Transplant. 2008 Jun; 13(3):273-4. Mandell MS, Niemann CU. PMID: 18685316.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    53. Transient hyperglycemia affects the extent of ischemia-reperfusion-induced renal injury in rats. Anesthesiology. 2008 Mar; 108(3):402-14. Hirose R, Xu F, Dang K, Liu T, Behrends M, Brakeman PR, Wiener-Kronish J, Niemann CU. PMID: 18292678.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    54. Increased severity of renal ischemia-reperfusion injury with venous clamping compared to arterial clamping in a rat model. Surgery. 2008 Feb; 143(2):243-51. Park Y, Hirose R, Dang K, Xu F, Behrends M, Tan V, Roberts JP, Niemann CU. PMID: 18242341.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    55. A multicenter evaluation of safety of early extubation in liver transplant recipients. Liver Transpl. 2007 Nov; 13(11):1557-63. Mandell MS, Stoner TJ, Barnett R, Shaked A, Bellamy M, Biancofiore G, Niemann C, Walia A, Vater Y, Tran ZV, Kam I. PMID: 17969193.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    56. Remote renal injury following partial hepatic ischemia/reperfusion injury in rats. J Gastrointest Surg. 2008 Mar; 12(3):490-5. Behrends M, Hirose R, Park YH, Tan V, Dang K, Xu F, Park SH, Niemann CU. PMID: 17701074.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    57. Biochemical mechanisms of nephrotoxicity: application for metabolomics. Expert Opin Drug Metab Toxicol. 2007 Aug; 3(4):527-44. Niemann CU, Serkova NJ. PMID: 17696804.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    58. Early detection of graft failure using the blood metabolic profile of a liver recipient. Transplantation. 2007 Feb 27; 83(4):517-21. Serkova NJ, Zhang Y, Coatney JL, Hunter L, Wachs ME, Niemann CU, Mandell MS. PMID: 17318087.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    59. Glutamine donor pretreatment in rat kidney transplants with severe preservation reperfusion injury. J Surg Res. 2007 Jun 01; 140(1):77-83. Fuller TF, Rose F, Singleton KD, Linde Y, Hoff U, Freise CE, Dragun D, Niemann CU. PMID: 17292409.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    60. Central venous pressure monitoring during living right donor hepatectomy. Liver Transpl. 2007 Feb; 13(2):266-71. Niemann CU, Feiner J, Behrends M, Eilers H, Ascher NL, Roberts JP. PMID: 17256757.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    61. Ischemia-reperfusion injury is more severe in older versus young rat livers. J Surg Res. 2007 Jan; 137(1):96-102. Park Y, Hirose R, Coatney JL, Ferrell L, Behrends M, Roberts JP, Serkova NJ, Niemann CU. PMID: 17064732.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    62. Pattern recognition and biomarker validation using quantitative 1H-NMR-based metabolomics. Expert Rev Mol Diagn. 2006 Sep; 6(5):717-31. Serkova NJ, Niemann CU. PMID: 17009906.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimals
    63. Mild hypothermia reduces the inflammatory response and hepatic ischemia/reperfusion injury in rats. Liver Int. 2006 Aug; 26(6):734-41. Behrends M, Hirose R, Serkova NJ, Coatney JL, Bedolli M, Yardi J, Park YH, Niemann CU. PMID: 16842331.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    64. Mild hypothermia protects obese rats from fulminant hepatic necrosis induced by ischemia-reperfusion. Surgery. 2006 Sep; 140(3):404-12. Niemann CU, Choi S, Behrends M, Hirose R, Noh J, Coatney JL, Roberts JP, Serkova NJ, Maher JJ. PMID: 16934602.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    65. Recombinant factor VIIa reduces transfusion requirements in liver transplant patients with high MELD scores. Transfus Med. 2006 Apr; 16(2):93-100. Niemann CU, Behrends M, Quan D, Eilers H, Gropper MA, Roberts JP, Hirose R. PMID: 16623915.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    66. Warm ischemia-induced alterations in oxidative and inflammatory proteins in hepatic Kupffer cells in rats. Mol Cell Proteomics. 2006 Jun; 5(6):979-86. Hirsch J, Hansen KC, Choi S, Noh J, Hirose R, Roberts JP, Matthay MA, Burlingame AL, Maher JJ, Niemann CU. PMID: 16500929.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    67. Glutamine does not protect against hepatic warm ischemia/reperfusion injury in rats. J Gastrointest Surg. 2006 Feb; 10(2):234-9. Noh J, Behrends M, Choi S, Bedolli MA, Yardi J, Hirose R, Niemann CU. PMID: 16455456.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    68. Ischemic preconditioning improves energy state and transplantation survival in obese Zucker rat livers. Anesth Analg. 2005 Dec; 101(6):1577-83. Niemann CU, Hirose R, Liu T, Behrends M, Brown JL, Kominsky DF, Roberts JP, Serkova N. PMID: 16301222.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    69. Metabolic profiling of livers and blood from obese Zucker rats. J Hepatol. 2006 May; 44(5):956-62. Serkova NJ, Jackman M, Brown JL, Liu T, Hirose R, Roberts JP, Maher JJ, Niemann CU. PMID: 16223541.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    70. H-NMR-based metabolic signatures of mild and severe ischemia/reperfusion injury in rat kidney transplants. Kidney Int. 2005 Mar; 67(3):1142-51. Serkova N, Fuller TF, Klawitter J, Freise CE, Niemann CU. PMID: 15698456.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    71. Mild hypothermia provides significant protection against ischemia/reperfusion injury in livers of obese and lean rats. Ann Surg. 2005 Mar; 241(3):470-6. Choi S, Noh J, Hirose R, Ferell L, Bedolli M, Roberts JP, Niemann CU. PMID: 15729070.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    72. Ischemic preconditioning improves rat kidney graft function after severe ischemia/reperfusion injury. Transplant Proc. 2005 Jan-Feb; 37(1):377-8. Fuller TF, Freise CE, Feng S, Niemann CU. PMID: 15808650.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    73. Automated, fast, and sensitive quantification of drugs in human plasma by LC/LC-MS: quantification of 6 protease inhibitors and 3 nonnucleoside transcriptase inhibitors. Ther Drug Monit. 2004 Oct; 26(5):546-62. Egge-Jacobsen W, Unger M, Niemann CU, Baluom M, Hirai S, Benet LZ, Christians U. PMID: 15385839.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    74. Beta-adrenergic blockade affects initial drug distribution due to decreased cardiac output and altered blood flow distribution. J Pharmacol Exp Ther. 2004 Nov; 311(2):617-24. Avram MJ, Krejcie TC, Henthorn TK, Niemann CU. PMID: 15197245.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    75. Intraoperative fluid management of living donor versus cadaveric liver transplant recipients. Transplant Proc. 2004 Jun; 36(5):1466-8. Niemann CU, Hirose R, Stock P, Roberts JP, Mandell S, Spencer Yost C. PMID: 15251359.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    76. Influence of donor pretreatment with N-acetylcysteine on ischemia/reperfusion injury in rat kidney grafts. J Urol. 2004 Mar; 171(3):1296-300. Fuller TF, Serkova N, Niemann CU, Freise CE. PMID: 14767336.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    77. Sirolimus delays recovery of rat kidney transplants after ischemia-reperfusion injury. Transplantation. 2003 Dec 15; 76(11):1594-9. Fuller TF, Freise CE, Serkova N, Niemann CU, Olson JL, Feng S. PMID: 14702530.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    78. The effects of desflurane and propofol on portosystemic pressure in patients with portal hypertension. Anesth Analg. 2003 Dec; 97(6):1573-7. Mandell MS, Durham J, Kumpe D, Trotter JF, Everson GT, Niemann CU. PMID: 14633521.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    79. Mechanism of pupillary reflex dilation in awake volunteers and in organ donors. Anesthesiology. 2003 Dec; 99(6):1281-6. Yang LL, Niemann CU, Larson MD. PMID: 14639139.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    80. Organ-specific response to inhibition of mitochondrial metabolism by cyclosporine in the rat. Transpl Int. 2003 Oct; 16(10):748-55. Serkova N, Klawitter J, Niemann CU. PMID: 12827232.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    81. Clinically important drug interactions with intravenous anaesthetics in older patients. Drugs Aging. 2003; 20(13):969-80. Eilers H, Niemann C. PMID: 14561101.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    82. Intraoperative hemodynamics and liver function in adult-to-adult living liver donors. Liver Transpl. 2002 Dec; 8(12):1126-32. Niemann CU, Roberts JP, Ascher NL, Yost CS. PMID: 12474151.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    83. Elimination of indocyanine green in the perioperative evaluation of donor liver function. Anesth Analg. 2002 Nov; 95(5):1182-4, table of contents. Mandell MS, Wachs M, Niemann CU, Henthorn TK. PMID: 12401588.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    84. Cyclosporine can increase isoflurane MAC. Anesth Analg. 2002 Oct; 95(4):930-4, table of contents. Niemann CU, Stabernack C, Serkova N, Jacobsen W, Christians U, Eger EI. PMID: 12351270.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    85. Close association between the reduction in myocardial energy metabolism and infarct size: dose-response assessment of cyclosporine. J Pharmacol Exp Ther. 2002 Sep; 302(3):1123-8. Niemann CU, Saeed M, Akbari H, Jacobsen W, Benet LZ, Christians U, Serkova N. PMID: 12183671.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    86. Evaluation of the splanchnic circulation with indocyanine green pharmacokinetics in liver transplant patients. Liver Transpl. 2002 May; 8(5):476-81. Niemann CU, Yost CS, Mandell S, Henthorn TK. PMID: 12004348.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    87. Comparison of the effects of cyclosporin a on the metabolism of perfused rat brain slices during normoxia and hypoxia. J Cereb Blood Flow Metab. 2002 Mar; 22(3):342-52. Serkova N, Donohoe P, Gottschalk S, Hainz C, Niemann CU, Bickler PE, Litt L, Benet LZ, Leibfritz D, Christians U. PMID: 11891440.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    88. Sirolimus, but not the structurally related RAD (everolimus), enhances the negative effects of cyclosporine on mitochondrial metabolism in the rat brain. Br J Pharmacol. 2001 Jul; 133(6):875-85. Serkova N, Jacobsen W, Niemann CU, Litt L, Benet LZ, Leibfritz D, Christians U. PMID: 11454661.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    89. Isoflurane alters the recirculatory pharmacokinetics of physiologic markers. Anesthesiology. 2000 Jun; 92(6):1757-68. Avram MJ, Krejcie TC, Niemann CU, Enders-Klein C, Shanks CA, Henthorn TK. PMID: 10839928.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    90. Indocyanine green kinetics characterize blood volume and flow distribution and their alteration by propranolol. Clin Pharmacol Ther. 2000 Apr; 67(4):342-50. Niemann CU, Henthorn TK, Krejcie TC, Shanks CA, Enders-Klein C, Avram MJ. PMID: 10801242.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    91. Ketamine distribution described by a recirculatory pharmacokinetic model is not stereoselective. Anesthesiology. 1999 Dec; 91(6):1733-43. Henthorn TK, Krejcie TC, Niemann CU, Enders-Klein C, Shanks CA, Avram MJ. PMID: 10598617.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    92. Modifications of blood volume alter the disposition of markers of blood volume, extracellular fluid, and total body water. J Pharmacol Exp Ther. 1999 Dec; 291(3):1308-16. Krejcie TC, Henthorn TK, Gentry WB, Niemann CU, Enders-Klein C, Shanks CA, Avram MJ. PMID: 10565856.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    93. The effect of halothane on the recirculatory pharmacokinetics of physiologic markers. Anesthesiology. 1997 Dec; 87(6):1381-93. Avram MJ, Krejcie TC, Niemann CU, Klein C, Gentry WB, Shanks CA, Henthorn TK. PMID: 9416724.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    94. A recirculatory model of the pulmonary uptake and pharmacokinetics of lidocaine based on analysis of arterial and mixed venous data from dogs. J Pharmacokinet Biopharm. 1997 Apr; 25(2):169-90. Krejcie TC, Avram MJ, Gentry WB, Niemann CU, Janowski MP, Henthorn TK. PMID: 9408858.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    95. Use of parallel Erlang density functions to analyze first-pass pulmonary uptake of multiple indicators in dogs. J Pharmacokinet Biopharm. 1996 Dec; 24(6):569-88. Krejcie TC, Jacquez JA, Avram MJ, Niemann CU, Shanks CA, Henthorn TK. PMID: 9300351.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    96. Recirculatory pharmacokinetic models of markers of blood, extracellular fluid and total body water administered concomitantly. J Pharmacol Exp Ther. 1996 Sep; 278(3):1050-7. Krejcie TC, Henthorn TK, Niemann CU, Klein C, Gupta DK, Gentry WB, Shanks CA, Avram MJ. PMID: 8819485.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
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