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Jacquelyn Maher, MD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address513 Parnassus Ave, HSE
San Francisco CA 94143
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    Collapse Biography 
    Collapse Education and Training
    Duke UniversityB.A1976Chemistry
    Duke University School of MedicineM.D.1979
    Duke University Medical CenterResidency 1983Internal Medicine
    University of California, San FranciscoFellowship1987Gastroenterology

    Collapse Overview 
    Collapse Overview
    Dr. Maher is Chief of the Division of Gastroenterology at San Francisco General Hospital and Director of the UCSF Liver Center. Research in her laboratory focuses on the pathogenesis of fatty liver disease. Special emphasis is placed on the effects of individual dietary macronutrients on liver injury. Her studies in mice implicate dietary sugar as an important inducer of fatty liver disease, through conversion to toxic saturated fatty acids. Ongoing work in her group concentrates on the synergistic toxicity of carbohydrates and saturated fats, and explores how adipose tissue in obesity adversely affects the liver. She uses stem cells from patients with fatty liver disease to study what makes their livers susceptible to injury.

    Collapse Research 
    Collapse Research Activities and Funding
    Using disease-specific iPS cells to investigate fatty liver disease in a diverse human cohort
    NIH/NIDDK R21DK118380Sep 15, 2018 - Jun 30, 2020
    Role: Principal Investigator
    Dietary Factors in the Pathogenesis of Steatohepatitis
    NIH/NIDDK R01DK068450Aug 1, 2004 - Mar 31, 2015
    Role: Principal Investigator
    NRSA Hepatology Training Grant
    NIH/NIDDK T32DK060414Dec 1, 2001 - Nov 30, 2006
    Role: Principal Investigator
    UCSF Liver Center
    NIH/NIDDK P30DK026743Dec 1, 1996 - Nov 30, 2000
    Role: Principal Investigator

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    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Doxycycline Significantly Enhances Induction of iPSCs to Endoderm by Enhancing survival via AKT Phosphorylation. BioRxiv. 2020. Cristina Esteva-Font, Tao Su, Caitlin Peaslee, Caroline Duwaerts, Ke Liu, Marisa Medina, Jacquelyn J. Maher, Aras N. Mattis.View Publication.
    2. Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation. Sci Rep. 2020 Apr 28; 10(1):7165. Alkhani A, Levy CS, Tsui M, Rosenberg KA, Polovina K, Mattis AN, Mack M, Van Dyken S, Wang BM, Maher JJ, Nijagal A. PMID: 32346042.
      View in: PubMed   Mentions:    Fields:    
    3. Nonalcoholic Fatty Liver Disease in 2020. Gastroenterology. 2020 May; 158(7):1849-1850. Maher JJ, Schattenberg JM. PMID: 32302525.
      View in: PubMed   Mentions:    Fields:    
    4. Hepatocyte-specific deletion of XBP1 sensitizes mice to liver injury through hyperactivation of IRE1a. BioRxiv. 2020. Duwaerts CC, Siao K, Soon RK, Her C, Iwawaki T, Kohno K, Mattis AN, Maher JJ.. View Publication.
    5. iPSC-derived hepatocytes from patients with nonalcoholic fatty liver disease display a disease-specific gene expression profile. BioRxiv. 2020. Duwaerts CC, Her CL, Phillips NJ, Willenbring H, Mattis AN, Maher JJ.. View Publication.
    6. Macronutrients and the Adipose-Liver Axis in Obesity and Fatty Liver. Cell Mol Gastroenterol Hepatol. 2019; 7(4):749-761. Duwaerts CC, Maher JJ. PMID: 30763771.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    7. Loss of Integrin avß8 in Murine Hepatocytes Accelerates Liver Regeneration. Am J Pathol. 2019 02; 189(2):258-271. Greenhalgh SN, Matchett KP, Taylor RS, Huang K, Li JT, Saeteurn K, Donnelly MC, Simpson EEM, Pollack JL, Atakilit A, Simpson KJ, Maher JJ, Iredale JP, Sheppard D, Henderson NC. PMID: 30448409.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    8. Macrophages Steal STING From the Infectious Disease Playbook to Promote Nonalcoholic Fatty Liver Disease. Gastroenterology. 2018 12; 155(6):1687-1688. Maher JJ. PMID: 30419212.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    9. Race/ethnicity is an independent risk factor for autoimmune hepatitis among the San Francisco underserved. Autoimmunity. 2018 08; 51(5):258-264. Lee B, Holt EW, Wong RJ, Sewell JL, Somsouk M, Khalili M, Maher JJ, Tana MM. PMID: 29890851.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Hospitalizations for Autoimmune Hepatitis Disproportionately Affect Black and Latino Americans. Am J Gastroenterol. 2018 02; 113(2):243-253. Wen JW, Kohn MA, Wong R, Somsouk M, Khalili M, Maher J, Tana MM. PMID: 29380822.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. CD18 deficiency improves liver injury in the MCD model of steatohepatitis. PLoS One. 2017; 12(9):e0183912. Pierce AA, Duwaerts CC, Siao K, Mattis AN, Goodsell A, Baron JL, Maher JJ. PMID: 28873429.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    12. Specific Macronutrients Exert Unique Influences on the Adipose-Liver Axis to Promote Hepatic Steatosis in Mice. Cell Mol Gastroenterol Hepatol. 2017 Sep; 4(2):223-236. Duwaerts CC, Amin AM, Siao K, Her C, Fitch M, Beysen C, Turner SM, Goodsell A, Baron JL, Grenert JP, Cho SJ, Maher JJ. PMID: 28649594.
      View in: PubMed   Mentions: 1     Fields:    
    13. Modeling fatty liver disease in animals: Is there an optimal approach, and is the effort worthwhile? Hepatology. 2016 11; 64(5):1398-1400. Maher JJ. PMID: 27639263.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    14. Pathogenesis of NAFLD and NASH. Alcoholic and Non-Alcoholic Fatty Liver Disease. 2016 Jan 1; 71-101. Jacquelyn J. Maher. .
      View in: Publisher Site   Mentions:
    15. Nonalcoholic fatty liver disease. Nat Rev Dis Primers. 2015 12 17; 1:15080. Brunt EM, Wong VW, Nobili V, Day CP, Sookoian S, Maher JJ, Bugianesi E, Sirlin CB, Neuschwander-Tetri BA, Rinella ME. PMID: 27188459.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansCells
    16. Isocaloric manipulation of macronutrients within a high-carbohydrate/moderate-fat diet induces unique effects on hepatic lipogenesis, steatosis and liver injury. J Nutr Biochem. 2016 Mar; 29:12-20. Pierce AA, Duwaerts CC, Soon RK, Siao K, Grenert JP, Fitch M, Hellerstein MK, Beysen C, Turner SM, Maher JJ. PMID: 26895660.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    17. Differential hepatotoxicity of dietary and DNL-derived palmitate in the methionine-choline-deficient model of steatohepatitis. BMC Gastroenterol. 2015 Jun 24; 15:72. Pierce AA, Pickens MK, Siao K, Grenert JP, Maher JJ. PMID: 26103964.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    18. A screen in mice uncovers repression of lipoprotein lipase by microRNA-29a as a mechanism for lipid distribution away from the liver. Hepatology. 2015 Jan; 61(1):141-52. Mattis AN, Song G, Hitchner K, Kim RY, Lee AY, Sharma AD, Malato Y, McManus MT, Esau CC, Koller E, Koliwad S, Lim LP, Maher JJ, Raffai RL, Willenbring H. PMID: 25131933.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    19. Mechanisms of Liver Injury in Non-Alcoholic Steatohepatitis. Curr Hepatol Rep. 2014 Jun 01; 13(2):119-129. Duwaerts CC, Maher JJ. PMID: 25045618.
      View in: PubMed   Mentions:
    20. Circulating interleukin-8 levels explain breast cancer osteolysis in mice and humans. Bone. 2014 Apr; 61:176-85. Kamalakar A, Bendre MS, Washam CL, Fowler TW, Carver A, Dilley JD, Bracey JW, Akel NS, Margulies AG, Skinner RA, Swain FL, Hogue WR, Montgomery CO, Lahiji P, Maher JJ, Leitzel KE, Ali SM, Lipton A, Nicholas RW, Gaddy D, Suva LJ. PMID: 24486955.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    21. Targeting of av integrin identifies a core molecular pathway that regulates fibrosis in several organs. Nat Med. 2013 Dec; 19(12):1617-24. Henderson NC, Arnold TD, Katamura Y, Giacomini MM, Rodriguez JD, McCarty JH, Pellicoro A, Raschperger E, Betsholtz C, Ruminski PG, Griggs DW, Prinsen MJ, Maher JJ, Iredale JP, Lacy-Hulbert A, Adams RH, Sheppard D. PMID: 24216753.
      View in: PubMed   Mentions: 217     Fields:    Translation:AnimalsCells
    22. A liver Hif-2a-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition. Nat Med. 2013 Oct; 19(10):1331-1337. Wei K, Piecewicz SM, McGinnis LM, Taniguchi CM, Wiegand SJ, Anderson K, Chan CW, Mulligan KX, Kuo D, Yuan J, Vallon M, Morton L, Lefai E, Simon MC, Maher JJ, Mithieux G, Rajas F, Annes J, McGuinness OP, Thurston G, Giaccia AJ, Kuo CJ. PMID: 24037094.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    23. Retinol binding protein 4 and fatty liver: A direct link? Hepatology. 2013 Aug; 58(2):477-9. Maher JJ. PMID: 23703940.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    24. Hepatic fibrosis: evaluation with semiquantitative contrast-enhanced CT. Radiology. 2013 Jan; 266(1):151-8. Varenika V, Fu Y, Maher JJ, Gao D, Kakar S, Cabarrus MC, Yeh BM. PMID: 23169796.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    25. Insulin sensitivity and variability in hepatitis C virus infection using direct measurement. Dig Dis Sci. 2013 Apr; 58(4):1141-8. Mukhtar NA, Bacchetti P, Ayala CE, Melgar J, Christensen S, Maher JJ, Khalili M. PMID: 23086116.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    26. The basic helix-loop-helix transcription factor, heart and neural crest derivatives expressed transcript 2, marks hepatic stellate cells in zebrafish: analysis of stellate cell entry into the developing liver. Hepatology. 2012 Nov; 56(5):1958-70. Yin C, Evason KJ, Maher JJ, Stainier DY. PMID: 22488653.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    27. Specific bile acids inhibit hepatic fatty acid uptake in mice. Hepatology. 2012 Oct; 56(4):1300-10. Nie B, Park HM, Kazantzis M, Lin M, Henkin A, Ng S, Song S, Chen Y, Tran H, Lai R, Her C, Maher JJ, Forman BM, Stahl A. PMID: 22531947.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    28. Impact of insulin resistance on HCV treatment response and impact of HCV treatment on insulin sensitivity using direct measurements of insulin action. Diabetes Care. 2012 May; 35(5):1090-4. Brandman D, Bacchetti P, Ayala CE, Maher JJ, Khalili M. PMID: 22399695.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsCTClinical Trials
    29. Assessment of factors associated with pre-diabetes in HCV infection including direct and dynamic measurements of insulin action. J Viral Hepat. 2012 Jul; 19(7):480-7. Mukhtar NA, Ayala C, Maher JJ, Khalili M. PMID: 22676360.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    30. Lipids in liver disease: looking beyond steatosis. Gastroenterology. 2012 Jan; 142(1):8-11. Schwabe RF, Maher JJ. PMID: 22107717.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    31. New insights from rodent models of fatty liver disease. Antioxid Redox Signal. 2011 Jul 15; 15(2):535-50. Maher JJ. PMID: 21126212.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    32. Stress signaling in the methionine-choline-deficient model of murine fatty liver disease. Gastroenterology. 2010 Nov; 139(5):1730-9, 1739.e1. Soon RK, Yan JS, Grenert JP, Maher JJ. PMID: 20682321.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    33. Comparison of surrogate and direct measurement of insulin resistance in chronic hepatitis C virus infection: impact of obesity and ethnicity. Hepatology. 2010 Jul; 52(1):38-46. Lam KD, Bacchetti P, Abbasi F, Ayala CE, Loeb SM, Shah V, Wen MJ, Reaven GM, Maher JJ, Khalili M. PMID: 20578127.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    34. Computational experiments reveal plausible mechanisms for changing patterns of hepatic zonation of xenobiotic clearance and hepatotoxicity. J Theor Biol. 2010 Aug 21; 265(4):718-33. Sheikh-Bahaei S, Maher JJ, Anthony Hunt C. PMID: 20541559.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    35. Dietary fructose exacerbates hepatocellular injury when incorporated into a methionine-choline-deficient diet. Liver Int. 2010 Sep; 30(8):1229-39. Pickens MK, Ogata H, Soon RK, Grenert JP, Maher JJ. PMID: 20536716.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    36. Trunk fat as a determinant of liver disease. Gastroenterology. 2010 Apr; 138(4):1244-6. Maher JJ. PMID: 20184974.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    37. Short passive cooling protects rats during hepatectomy by inducing heat shock proteins and limiting the induction of pro-inflammatory cytokines. J Surg Res. 2010 Jan; 158(1):43-52. Niemann CU, Xu F, Choi S, Behrends M, Park Y, Hirose R, Maher JJ. PMID: 19394963.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    38. Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis. J Lipid Res. 2009 Oct; 50(10):2072-82. Pickens MK, Yan JS, Ng RK, Ogata H, Grenert JP, Beysen C, Turner SM, Maher JJ. PMID: 19295183.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    39. DAMPs ramp up drug toxicity. J Clin Invest. 2009 Feb; 119(2):246-9. Maher JJ. PMID: 19244605.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    40. Beyond insulin resistance: Innate immunity in nonalcoholic steatohepatitis. Hepatology. 2008 Aug; 48(2):670-8. Maher JJ, Leon P, Ryan JC. PMID: 18666225.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    41. Impaired dexamethasone-mediated induction of tryptophan 2,3-dioxygenase in heme-deficient rat hepatocytes: translational control by a hepatic eIF2alpha kinase, the heme-regulated inhibitor. J Pharmacol Exp Ther. 2007 Dec; 323(3):979-89. Liao M, Pabarcus MK, Wang Y, Hefner C, Maltby DA, Medzihradszky KF, Salas-Castillo SP, Yan J, Maher JJ, Correia MA. PMID: 17761498.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    42. Characterization of the physiological turnover of native and inactivated cytochromes P450 3A in cultured rat hepatocytes: a role for the cytosolic AAA ATPase p97? Biochemistry. 2007 Jul 03; 46(26):7793-803. Faouzi S, Medzihradszky KF, Hefner C, Maher JJ, Correia MA. PMID: 17550236.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    43. Polyunsaturated fat in the methionine-choline-deficient diet influences hepatic inflammation but not hepatocellular injury. J Lipid Res. 2007 Aug; 48(8):1885-96. Lee GS, Yan JS, Ng RK, Kakar S, Maher JJ. PMID: 17526933.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    44. Alcoholic steatohepatitis: management and prognosis. Curr Gastroenterol Rep. 2007 Mar; 9(1):39-46. Maher JJ. PMID: 17335676.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    45. Mild hypothermia protects obese rats from fulminant hepatic necrosis induced by ischemia-reperfusion. Surgery. 2006 Sep; 140(3):404-12. Niemann CU, Choi S, Behrends M, Hirose R, Noh J, Coatney JL, Roberts JP, Serkova NJ, Maher JJ. PMID: 16934602.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    46. Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1. J Lipid Res. 2006 Oct; 47(10):2280-90. Rizki G, Arnaboldi L, Gabrielli B, Yan J, Lee GS, Ng RK, Turner SM, Badger TM, Pitas RE, Maher JJ. PMID: 16829692.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    47. VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis. Nat Med. 2006 Jul; 12(7):793-800. Tam BY, Wei K, Rudge JS, Hoffman J, Holash J, Park SK, Yuan J, Hefner C, Chartier C, Lee JS, Jiang S, Nayak NR, Niyak NR, Kuypers FA, Ma L, Sundram U, Wu G, Garcia JA, Schrier SL, Maher JJ, Johnson RS, Yancopoulos GD, Mulligan RC, Kuo CJ. PMID: 16799557.
      View in: PubMed   Mentions: 58     Fields:    Translation:Animals
    48. ANIT toxicity toward mouse hepatocytes in vivo is mediated primarily by neutrophils via CD18. Am J Physiol Gastrointest Liver Physiol. 2006 Aug; 291(2):G355-63. Kodali P, Wu P, Lahiji PA, Brown EJ, Maher JJ. PMID: 16614373.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    49. Warm ischemia-induced alterations in oxidative and inflammatory proteins in hepatic Kupffer cells in rats. Mol Cell Proteomics. 2006 Jun; 5(6):979-86. Hirsch J, Hansen KC, Choi S, Noh J, Hirose R, Roberts JP, Matthay MA, Burlingame AL, Maher JJ, Niemann CU. PMID: 16500929.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    50. Metabolic profiling of livers and blood from obese Zucker rats. J Hepatol. 2006 May; 44(5):956-62. Serkova NJ, Jackman M, Brown JL, Liu T, Hirose R, Roberts JP, Maher JJ, Niemann CU. PMID: 16223541.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    51. Transgenic overexpression of interleukin-8 in mouse liver protects against galactosamine/endotoxin toxicity. J Hepatol. 2006 Feb; 44(2):359-67. Hanson JC, Bostick MK, Campe CB, Kodali P, Lee G, Yan J, Maher JJ. PMID: 16168518.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    52. Heme-reversible impairment of CYP2B1/2 induction in heme-depleted rat hepatocytes in primary culture: translational control by a hepatic alpha-subunit of the eukaryotic initiation factor kinase? J Pharmacol Exp Ther. 2005 Jul; 314(1):128-38. Han XM, Lee G, Hefner C, Maher JJ, Correia MA. PMID: 15769864.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    53. Limited role for CXC chemokines in the pathogenesis of alpha-naphthylisothiocyanate-induced liver injury. Am J Physiol Gastrointest Liver Physiol. 2004 Sep; 287(3):G734-41. Xu J, Lee G, Wang H, Vierling JM, Maher JJ. PMID: 15130876.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    54. What doesn't kill you makes you stronger: how hepatocytes survive prolonged cholestasis. Hepatology. 2004 Apr; 39(4):1141-3. Maher JJ. PMID: 15057918.
      View in: PubMed   Mentions: 3     Fields:    
    55. Infiltrating neutrophils in bile duct-ligated livers do not promote hepatic fibrosis. Hepatol Res. 2003 Feb; 25(2):180-191. Saito JM, Bostick MK, Campe CB, Xu J, Maher JJ. PMID: 12644055.
      View in: PubMed   Mentions:
    56. 713 A lipogenic diet deficient in methionine and choline (MCD) suppresses hepatic stearoyl-COA desaturase-1: a possible role for lipotoxicity in the pathogenesis of MCD-induced steatohepatitis. Hepatology. 2003 Jan 1; 38:502. Gizem Rizki, Lorenzo Arnaboldi, Bianca Gabrielli, Gene Lee, Robert E. Pitas, Jacquelyn J. Maher. .
      View in: Publisher Site   Mentions:
    57. Treatment of alcoholic hepatitis. J Gastroenterol Hepatol. 2002 Apr; 17(4):448-55. Maher JJ. PMID: 11982726.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    58. Alcoholic steatosis and steatohepatitis. Semin Gastrointest Dis. 2002 Jan; 13(1):31-9. Maher JJ. PMID: 11944632.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    59. Blocking the secretion of hepatic very low density lipoproteins renders the liver more susceptible to toxin-induced injury. J Biol Chem. 2002 Feb 15; 277(7):5476-83. Björkegren J, Beigneux A, Bergo MO, Maher JJ, Young SG. PMID: 11739387.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    60. Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kappa B-independent, caspase-3-dependent pathway. J Biol Chem. 2001 Dec 28; 276(52):49077-82. Faouzi S, Burckhardt BE, Hanson JC, Campe CB, Schrum LW, Rippe RA, Maher JJ. PMID: 11602613.
      View in: PubMed   Mentions: 49     Fields:    Translation:Animals
    61. Interactions between hepatic stellate cells and the immune system. Semin Liver Dis. 2001 Aug; 21(3):417-26. Maher JJ. PMID: 11586469.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    62. Cholesterol esterification by host and parasite is essential for optimal proliferation of Toxoplasma gondii. J Biol Chem. 2001 Sep 14; 276(37):34434-40. Sonda S, Ting LM, Novak S, Kim K, Maher JJ, Farese RV, Ernst JD. PMID: 11457847.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    63. Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice. J Cell Biol. 2001 May 28; 153(5):1023-34. Wang R, Ferrell LD, Faouzi S, Maher JJ, Bishop JM. PMID: 11381087.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimalsCells
    64. Antidiabetic treatment for NASH? Hepatology. 2001 May; 33(5):1338-9. Maher J. PMID: 11343267.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    65. The CYP2E1 knockout delivers another punch: first ASH, now NASH. Alcoholic steatohepatitis. Nonalcoholic steatohepatitis. Hepatology. 2001 Jan; 33(1):311-2. Maher J. PMID: 11124851.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    66. Bile duct ligation in rats induces biliary expression of cytokine-induced neutrophil chemoattractant. Gastroenterology. 2000 Jun; 118(6):1157-68. Saito JM, Maher JJ. PMID: 10833491.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    67. Leukocytes as modulators of stellate cell activation. Alcohol Clin Exp Res. 1999 May; 23(5):917-21. Maher JJ. PMID: 10371414.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    68. Cytokines: overview. Semin Liver Dis. 1999; 19(2):109-15. Maher JJ. PMID: 10422194.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    69. How does estrogen enhance endotoxin toxicity? Let me count the ways. Hepatology. 1998 Dec; 28(6):1720-1. Maher JJ. PMID: 9828242.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    70. Rat hepatic stellate cells produce cytokine-induced neutrophil chemoattractant in culture and in vivo. Am J Physiol. 1998 10; 275(4):G847-53. Maher JJ, Lozier JS, Scott MK. PMID: 9756517.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    71. CHEMOKINES AND ALCOHOLIC LIVER DISEASE. Alcoholism Clinical and Experimental Research. 1998 May 1; 22(3):759-760. Jacquelyn J. Maher. .
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    72. The extracellular matrix in liver regeneration. Liver Growth and Repair. 1998 Jan 1; 451-464. Jacquelyn J. Maher. .
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    73. Manipulation of glutathione stores in rat hepatic stellate cells does not alter collagen synthesis. Hepatology. 1997 Sep; 26(3):618-23. Maher JJ, Neuschwander-Tetri BA. PMID: 9303491.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    74. Glutathione regulation in rat hepatic stellate cells. Comparative studies in primary culture and in liver injury in vivo. Biochem Pharmacol. 1997 Mar 07; 53(5):637-41. Maher JJ, Saito JM, Neuschwander-Tetri BA. PMID: 9113082.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    75. Adenovirus-mediated expression of cytokine-induced neutrophil chemoattractant in rat liver induces a neutrophilic hepatitis. Hepatology. 1997 Mar; 25(3):624-30. Maher JJ, Scott MK, Saito JM, Burton MC. PMID: 9049209.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    76. Exploring alcohol's effects on liver function. Alcohol Health Res World. 1997; 21(1):5-12. Maher JJ. PMID: 15706758.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    77. Rat hepatocytes and Kupffer cells interact to produce interleukin-8 (CINC) in the setting of ethanol. Am J Physiol. 1995 Oct; 269(4 Pt 1):G518-23. Maher JJ. PMID: 7485503.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    78. Malondialdehyde stimulates collagen production by hepatic lipocytes only upon activation in primary culture. Alcohol Alcohol. 1994 Sep; 29(5):605-10. Maher JJ, Tzagarakis C, Giménez A. PMID: 7811345.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    79. Acetaldehyde-induced stimulation of collagen synthesis and gene expression is dependent on conditions of cell culture: studies with rat lipocytes and fibroblasts. Alcohol Clin Exp Res. 1994 Apr; 18(2):403-9. Maher JJ, Zia S, Tzagarakis C. PMID: 8048746.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    80. Partial cloning of the M subunit of laminin from adult rat lipocytes: expression of the M subunit by cells isolated from normal and injured liver. Hepatology. 1994 Mar; 19(3):764-70. Maher JJ, Tzagarakis C. PMID: 8119705.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    81. Cell-matrix interactions in liver. Semin Cell Biol. 1993 Jun; 4(3):189-201. Maher JJ, Bissell DM. PMID: 7688595.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    82. Cell-specific expression of hepatocyte growth factor in liver. Upregulation in sinusoidal endothelial cells after carbon tetrachloride. J Clin Invest. 1993 May; 91(5):2244-52. Maher JJ. PMID: 7683700.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    83. Parenchymal and nonparenchymal cell interactions in the liver. Semin Liver Dis. 1993 Feb; 13(1):13-20. Maher JJ, Friedman SL. PMID: 8446905.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    84. Inhibition of rat hepatic lipocyte activation in culture by interferon-gamma. Hepatology. 1992 Sep; 16(3):776-84. Rockey DC, Maher JJ, Jarnagin WR, Gabbiani G, Friedman SL. PMID: 1505921.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    85. Isolated hepatic lipocytes and Kupffer cells from normal human liver: morphological and functional characteristics in primary culture. Hepatology. 1992 Feb; 15(2):234-43. Friedman SL, Rockey DC, McGuire RF, Maher JJ, Boyles JK, Yamasaki G. PMID: 1735526.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansCells
    86. Yet another role for the "good" matrix protein: laminin in regenerating liver. Hepatology. 1992 Jan; 15(1):164-6. Maher JJ. PMID: 1727793.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    87. Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo. J Clin Invest. 1990 Nov; 86(5):1641-8. Maher JJ, McGuire RF. PMID: 2243137.
      View in: PubMed   Mentions: 105     Fields:    Translation:Animals
    88. Connective tissue biology and hepatic fibrosis: report of a conference. Hepatology. 1990 Mar; 11(3):488-98. Bissell DM, Friedman SL, Maher JJ, Roll FJ. PMID: 2179098.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    89. Hepatic fibrosis caused by alcohol. Semin Liver Dis. 1990 Feb; 10(1):66-74. Maher JJ. PMID: 2186489.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    90. Fat-storing cells and myofibroblasts: one cell or two? Hepatology. 1989 Jun; 9(6):903-4. Maher JJ. PMID: 2714742.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    91. Primary hepatocyte culture: is it home away from home? Hepatology. 1988 Sep-Oct; 8(5):1162-6. Maher JJ. PMID: 3047039.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    92. Collagen measured in primary cultures of normal rat hepatocytes derives from lipocytes within the monolayer. J Clin Invest. 1988 Aug; 82(2):450-9. Maher JJ, Bissell DM, Friedman SL, Roll FJ. PMID: 3042806.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    93. Immunolocalization of laminin in normal rat liver and biosynthesis of laminin by hepatic lipocytes in primary culture. Gastroenterology. 1988 Apr; 94(4):1053-62. Maher JJ, Friedman SL, Roll FJ, Bissell DM. PMID: 3278941.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
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