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Richard Weiskopf, MD

Title(s)Professor Emeritus, Anesthesia
SchoolSchool of Medicine
Address500 Parnassus Avenue
San Francisco CA 94117
Phone--
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    Collapse Research 
    Collapse Research Activities and Funding
    Transfusion and Lung Injury
    NIH/NHLBI P50HL081027Sep 30, 2005 - Aug 31, 2011
    Role: Co-Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000079Dec 1, 1974 - Sep 29, 2006
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lower hemoglobin concentration decreases time to death in severely anemic patients for whom blood transfusion is not an option. J Trauma Acute Care Surg. 2020 Jun; 88(6):803-808. Guinn NR, Cooter ML, Weiskopf RB. PMID: 32102035.
      View in: PubMed   Mentions:    Fields:    
    2. Reassessment of the Need for an Oxygen Carrier for the Treatment of Traumatic Hemorrhage When Blood is not an Option. Shock. 2019 10; 52(1S Suppl 1):55-59. Pusateri AE, Glassberg E, Weiskopf RB. PMID: 31348149.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Hemoglobin-based Oxygen Carriers (HBOC)-What the Next Generation Holds: When Red Blood Cells are not an Option. Shock. 2019 10; 52(1S Suppl 1):4-6. Hill-Pryor C, Pusateri AE, Weiskopf RB. PMID: 31513122.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. The need for dried plasma - a national issue. Transfusion. 2019 04; 59(S2):1587-1592. Pusateri AE, Butler FK, Shackelford SA, Sperry JL, Moore EE, Cap AP, Taylor AL, Homer MJ, Hoots WK, Weiskopf RB, Davis MR. PMID: 30980738.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    5. Observing Blood Management Programs through the Retrospectroscope. Anesthesiology. 2018 12; 129(6):1060-1062. Cook RJ, Weiskopf RB. PMID: 30312181.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Severe anemia associated with increased risk of death and myocardial ischemia in patients declining blood transfusion. Transfusion. 2018 10; 58(10):2290-2296. Guinn NR, Cooter ML, Villalpando C, Weiskopf RB. PMID: 29797727.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Demonstrating therapeutic equivalence of a new and established pharmaceutical or intervention: a guide for the non-statistician. Transfusion. 2017 06; 57(6):1343-1346. Weiskopf RB, Cook RJ. PMID: 28345166.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Evaluating Pulmonary Function: An Assessment of PaO2/FIO2. Crit Care Med. 2017 Jan; 45(1):e40-e48. Feiner JR, Weiskopf RB. PMID: 27618274.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Addressing the unmet need of life-threatening anemia with hemoglobin-based oxygen carriers. Transfusion. 2017 01; 57(1):207-214. Weiskopf RB, Beliaev AM, Shander A, Guinn NR, Cap AP, Ness PM, Silverman TA. PMID: 27859328.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    10. Understanding non-inferiority trials and tests for the non-statistician: when to use them and how to interpret them. Transfusion. 2017 02; 57(2):240-243. Weiskopf RB, Cook RJ. PMID: 27861971.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. What is innovation? Transfusion. 2016 Mar; 56 Suppl 1:S3-5. Weiskopf RB. PMID: 27001359.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Lack of Nephrotoxicity of Hydroxyethyl Starch 130/0.4 When Used in Surgery. Anesthesiology. 2015 Aug; 123(2):482-3. Weiskopf RB. PMID: 26196877.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. A Clinical Trial to Detect Subclinical Transfusion-induced Lung Injury during Surgery. Anesthesiology. 2015 Jul; 123(1):126-35. Feiner JR, Gropper MA, Toy P, Lieberman J, Twiford J, Weiskopf RB. PMID: 25946480.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Update of use of hydroxyethyl starches in surgery and trauma. J Trauma Acute Care Surg. 2015 Jun; 78(6 Suppl 1):S54-9. Weiskopf RB, James MF. PMID: 26002264.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Hemoglobin-based oxygen carriers: disclosed history and the way ahead: the relativity of safety. Anesth Analg. 2014 Oct; 119(4):758-60. Weiskopf RB. PMID: 25232689.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    16. Hydroxyethyl starches: a tale of two contexts: the problem of knowledge. Anesth Analg. 2014 Sep; 119(3):509-13. Weiskopf RB. PMID: 25136996.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. The efficacy and safety of liquid stored blood and storage duration: a confused subject; are patients confused? Anesth Analg. 2014 Aug; 119(2):224-9. Weiskopf RB. PMID: 25046778.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. Trauma hemostasis and oxygenation research position paper on remote damage control resuscitation: definitions, current practice, and knowledge gaps. Shock. 2014 May; 41 Suppl 1:3-12. Jenkins DH, Rappold JF, Badloe JF, Berséus O, Blackbourne L, Brohi KH, Butler FK, Cap AP, Cohen MJ, Davenport R, DePasquale M, Doughty H, Glassberg E, Hervig T, Hooper TJ, Kozar R, Maegele M, Moore EE, Murdock A, Ness PM, Pati S, Rasmussen T, Sailliol A, Schreiber MA, Sunde GA, van de Watering LM, Ward KR, Weiskopf RB, White NJ, Strandenes G, Spinella PC. PMID: 24430539.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    19. Fluid Resuscitation for Hemorrhagic Shock in Tactical Combat Casualty Care: TCCC Guidelines Change 14-01--2 June 2014. J Spec Oper Med. 2014; 14(3):13-38. Butler FK, Holcomb JB, Schreiber MA, Kotwal RS, Jenkins DA, Champion HR, Bowling F, Cap AP, Dubose JJ, Dorlac WC, Dorlac GR, McSwain NE, Timby JW, Blackbourne LH, Stockinger ZT, Strandenes G, Weiskopf RB, Gross KR, Bailey JA. PMID: 25344706.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    20. Equivalent efficacy of hydroxyethyl starch 130/0.4 and human serum albumin: if nothing is the same, is everything different? The importance of context in clinical trials and statistics. Anesthesiology. 2013 Dec; 119(6):1249-54. Weiskopf RB. PMID: 24126265.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. In response. Anesth Analg. 2013 Aug; 117(2):530-1. Van Der Linden P, James M, Mythen M, Weiskopf RB. PMID: 24044131.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Balancing potential risks and benefits of hemoglobin-based oxygen carriers. Transfusion. 2013 Oct; 53(10):2327-33. Weiskopf RB, Silverman TA. PMID: 23869543.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    23. Tranexamic acid and trauma: current status and knowledge gaps with recommended research priorities. Shock. 2013 Feb; 39(2):121-6. Pusateri AE, Weiskopf RB, Bebarta V, Butler F, Cestero RF, Chaudry IH, Deal V, Dorlac WC, Gerhardt RT, Given MB, Hansen DR, Hoots WK, Klein HG, Macdonald VW, Mattox KL, Michael RA, Mogford J, Montcalm-Smith EA, Niemeyer DM, Prusaczyk WK, Rappold JF, Rassmussen T, Rentas F, Ross J, Thompson C, Tucker LD. PMID: 23222525.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    24. Transfusion for remote damage control resuscitation. Transfusion. 2013 Jan; 53 Suppl 1:1S-5S. Weiskopf RB, Ness PM. PMID: 23301968.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Transfusion for remote damage control resuscitation. Transfusion. 2013 Jan; 53(1):8-12. Weiskopf RB, Ness PM. PMID: 23294208.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    26. Safety of modern starches used during surgery. Anesth Analg. 2013 Jan; 116(1):35-48. Van Der Linden P, James M, Mythen M, Weiskopf RB. PMID: 23115254.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    27. Two septic transfusion reactions presenting as transfusion-related acute lung injury from a split plateletpheresis unit. Crit Care Med. 2012 Aug; 40(8):2488-91. Rollins MD, Molofsky AB, Nambiar A, Pandey S, Weiskopf RB, Toy P. PMID: 22809916.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    28. Reconstructing deconstructed blood for trauma. Anesthesiology. 2012 Mar; 116(3):518-21. Weiskopf RB. PMID: 22258018.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    29. From life-blood streaming to hemostasis. Anesth Analg. 2012 Feb; 114(2):247-9. Weiskopf RB. PMID: 22266693.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    30. Fresh red blood cell transfusion and short-term pulmonary, immunologic, and coagulation status: a randomized clinical trial. Am J Respir Crit Care Med. 2012 Apr 15; 185(8):842-50. Kor DJ, Kashyap R, Weiskopf RB, Wilson GA, van Buskirk CM, Winters JL, Malinchoc M, Hubmayr RD, Gajic O. PMID: 22281833.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansPHPublic Health
    31. Fresh and stored red blood cell transfusion equivalently induce subclinical pulmonary gas exchange deficit in normal humans. Anesth Analg. 2012 Mar; 114(3):511-9. Weiskopf RB, Feiner J, Toy P, Twiford J, Shimabukuro D, Lieberman J, Looney MR, Lowell CA, Gropper MA. PMID: 22262647.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    32. Transfusion-related acute lung injury: incidence and risk factors. Blood. 2012 Feb 16; 119(7):1757-67. Toy P, Gajic O, Bacchetti P, Looney MR, Gropper MA, Hubmayr R, Lowell CA, Norris PJ, Murphy EL, Weiskopf RB, Wilson G, Koenigsberg M, Lee D, Schuller R, Wu P, Grimes B, Gandhi MJ, Winters JL, Mair D, Hirschler N, Sanchez Rosen R, Matthay MA. PMID: 22117051.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansPHPublic Health
    33. High oxygen partial pressure decreases anemia-induced heart rate increase equivalent to transfusion. Anesthesiology. 2011 Sep; 115(3):492-8. Feiner JR, Finlay-Morreale HE, Toy P, Lieberman JA, Viele MK, Hopf HW, Weiskopf RB. PMID: 21768873.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    34. Blood samples, repositories, and ethics. Transfusion. 2011 May; 51(5):1123-5; author reply 1125. Weiskopf RB. PMID: 21545597.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    35. Challenges to effective research in acute trauma resuscitation: consent and endpoints. Shock. 2011 Feb; 35(2):107-13. Holcomb JB, Weiskopf R, Champion H, Gould SA, Sauer RM, Brasel K, Bochicchio G, Bulger E, Cotton BA, Davis D, Dutton R, Hauser CJ, Hess JR, Hides GA, Knudson P, MacKenzie E, McGinnis RL, Michalek J, Moore FA, Omert L, Pollock BH, Tortella B, Sugarman J, Schreiber MA, Wade CE. PMID: 20926987.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    36. Emergency transfusion for acute severe anemia: a calculated risk. Anesth Analg. 2010 Nov; 111(5):1088-92. Weiskopf RB. PMID: 20971958.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    37. Conflicts of interest in expert-authored practice parameters, standards, guidelines, recommendations. Anesthesiology. 2010 Sep; 113(3):751-2; author reply 752-3. Weiskopf RB. PMID: 20733391.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    38. Hemoglobin-based oxygen carriers: compassionate use and compassionate clinical trials. Anesth Analg. 2010 Mar 01; 110(3):659-62. Weiskopf RB. PMID: 20185643.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    39. Perioperative use of beta-adrenergic antagonists and anemia: known knowns, known unknowns, unknown unknowns; and Unknown Knowns. Anesthesiology. 2010 Jan; 112(1):12-5. Weiskopf RB. PMID: 20032697.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    40. Hemostasis in trauma. Transfusion. 2009 Dec; 49 Suppl 5:237S-9S. Weiskopf RB. PMID: 19954485.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    41. Hemoglobin-based oxygen carriers: current status and future directions. Anesthesiology. 2009 Nov; 111(5):946-63. Silverman TA, Weiskopf RB. PMID: 19858869.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    42. Hemoglobin-based oxygen carriers: current status and future directions. Transfusion. 2009 Nov; 49(11):2495-515. Silverman TA, Weiskopf RB. PMID: 19903298.
      View in: PubMed   Mentions: 18     Fields:    
    43. Prospective randomized clinical transfusion trials and statistical analysis. Transfusion. 2009 Aug; 49(8):1770; author reply 1770-1. Weiskopf RB. PMID: 19732405.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    44. Microarray kit analysis of cytokines in blood product units and segments. Transfusion. 2009 Nov; 49(11):2269-75. Weiskopf RB, Yau R, Sanchez R, Lowell C, Toy P. PMID: 19548981.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    45. Red blood cell age and function. Transfusion. 2008 Sep; 48(9):2026. Weiskopf RB, Feiner J, Toy P. PMID: 18811899.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    46. Volume replacement therapy during major orthopedic surgery using Voluven (hydroxyethyl starch 130/0.4) or hetastarch. Anesthesiology. 2007 Jun; 106(6):1120-7. Gandhi SD, Weiskopf RB, Jungheinrich C, Koorn R, Miller D, Shangraw RE, Prough DS, Baus D, Bepperling F, Warltier DC. PMID: 17525586.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    47. Visual loss after spinal surgery. Anesthesiology. 2007 Jun; 106(6):1250-1; author reply 1251-2. Weiskopf RB, Feiner J, Lieberman J, Hu SS. PMID: 17525614.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    48. Recombinant-activated coagulation factor VIIa (NovoSeven): current development. Vox Sang. 2007 May; 92(4):281-8. Weiskopf RB. PMID: 17456151.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    49. Food and Drug Administration public hearing on the draft guidance for exception from informed consent requirements for emergency research: testimony of Novo Nordisk. Acad Emerg Med. 2007 Apr; 14(4):e71-3. Weiskopf RB. PMID: 17322571.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    50. The role of data and safety monitoring in acute trauma resuscitation research. J Am Coll Surg. 2007 Jan; 204(1):73-83. Champion HR, Fingerhut A, Escobar MA, Weiskopf RB. PMID: 17189115.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    51. If you prick us, do we not bleed? Anesthesiology. 2006 Nov; 105(5):873-6. Weiskopf RB. PMID: 17065878.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    52. Anemia and perioperative red blood cell transfusion: a matter of tolerance. Crit Care Med. 2006 May; 34(5 Suppl):S102-8. Madjdpour C, Spahn DR, Weiskopf RB. PMID: 16617252.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    53. Fresh blood and aged stored blood are equally efficacious in immediately reversing anemia-induced brain oxygenation deficits in humans. Anesthesiology. 2006 May; 104(5):911-20. Weiskopf RB, Feiner J, Hopf H, Lieberman J, Finlay HE, Quah C, Kramer JH, Bostrom A, Toy P. PMID: 16645441.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    54. Extracellular potassium concentrations in red blood cell suspensions after irradiation and washing. Transfusion. 2005 Aug; 45(8):1295-301. Weiskopf RB, Schnapp S, Rouine-Rapp K, Bostrom A, Toy P. PMID: 16078915.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    55. Choosing the optimal endpoint(s) for a clinical trial on transfusion. Transfusion. 2005 Jul; 45(1 Suppl):1S. Hardy JF, Weiskopf RB. PMID: 15989683.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    56. A procedure for rapid issue of red cells for emergency use. Arch Pathol Lab Med. 2005 Apr; 129(4):492-6. Weiskopf RB, Webb M, Stangle D, Klinbergs G, Toy P. PMID: 15794672.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    57. Solubility of volatile anesthetics in bovine white matter, cortical gray matter, thalamus, hippocampus, and hypothalamic area. Anesth Analg. 2005 Apr; 100(4):1003-6. Neumann MA, Eger EI, Weiskopf RB. PMID: 15781514.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    58. Acute isovolemic anemia impairs central processing as determined by P300 latency. Clin Neurophysiol. 2005 May; 116(5):1028-32. Weiskopf RB, Toy P, Hopf HW, Feiner J, Finlay HE, Takahashi M, Bostrom A, Songster C, Aminoff MJ. PMID: 15826842.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    59. Research and evidence about blood sparing in spine surgery. Eur Spine J. 2004 Oct; 13 Suppl 1:S1-2. Szpalski M, Gunzburg R, Aebi M, Weiskopf R. PMID: 15480822.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    60. The use of recombinant activated coagulation factor VII for spine surgery. Eur Spine J. 2004 Oct; 13 Suppl 1:S83-8. Weiskopf RB. PMID: 15160317.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    61. Acute isovolemic anemia does not impair peripheral or central nerve conduction. Anesthesiology. 2003 Sep; 99(3):546-51. Weiskopf RB, Aminoff MJ, Hopf HW, Feiner J, Viele MK, Watson JJ, Ho R, Songster C, Toy P. PMID: 12960537.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCellsCTClinical Trials
    62. A comparison of intrathecal opioid and intravenous analgesia for the incidence of cardiovascular, respiratory, and renal complications after abdominal aortic surgery. Anesth Analg. 2003 Jul; 97(1):2-12, table of contents. Fléron MH, Weiskopf RB, Bertrand M, Mouren S, Eyraud D, Godet G, Riou B, Kieffer E, Coriat P. PMID: 12818934.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    63. Heart rate increases linearly in response to acute isovolemic anemia. Transfusion. 2003 Feb; 43(2):235-40. Weiskopf RB, Feiner J, Hopf H, Viele MK, Watson JJ, Lieberman J, Kelley S, Toy P. PMID: 12559019.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    64. Hemodilution and candles. Anesthesiology. 2002 Oct; 97(4):773-5. Weiskopf RB. PMID: 12357138.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    65. Intraoperative use of recombinant activated coagulation factor vII. Anesthesiology. 2002 Jun; 96(6):1287-9. Weiskopf RB. PMID: 12170037.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    66. Oxygen reverses deficits of cognitive function and memory and increased heart rate induced by acute severe isovolemic anemia. Anesthesiology. 2002 Apr; 96(4):871-7. Weiskopf RB, Feiner J, Hopf HW, Viele MK, Watson JJ, Kramer JH, Ho R, Toy P. PMID: 11964594.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCTClinical Trials
    67. Efficacy of acute normovolemic hemodilution assessed as a function of fraction of blood volume lost. Anesthesiology. 2001 Mar; 94(3):439-46. Weiskopf RB. PMID: 11374603.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    68. Electrocardiographic ST-segment changes during acute, severe isovolemic hemodilution in humans. Anesthesiology. 2000 Oct; 93(4):1004-10. Leung JM, Weiskopf RB, Feiner J, Hopf HW, Kelley S, Viele M, Lieberman J, Watson J, Noorani M, Pastor D, Yeap H, Ho R, Toy P. PMID: 11020755.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    69. Acute severe isovolemic anemia impairs cognitive function and memory in humans. Anesthesiology. 2000 Jun; 92(6):1646-52. Weiskopf RB, Kramer JH, Viele M, Neumann M, Feiner JR, Watson JJ, Hopf HW, Toy P. PMID: 10839915.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCTClinical Trials
    70. Erythrocyte salvage during cesarean section. Anesthesiology. 2000 Jun; 92(6):1519-22. Weiskopf RB. PMID: 10839899.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    71. Fatigue during acute isovolemic anemiain healthy, resting humans. Transfusion. 2000 Apr; 40(4):457-60. Toy P, Feiner J, Viele MK, Watson J, Yeap H, Weiskopf RB. PMID: 10773059.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    72. Critical oxygen delivery in conscious humans is less than 7.3 ml O2 x kg(-1) x min(-1). Anesthesiology. 2000 Feb; 92(2):407-13. Lieberman JA, Weiskopf RB, Kelley SD, Feiner J, Noorani M, Leung J, Toy P, Viele M. PMID: 10691227.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    73. The elimination of sodium and potassium hydroxides from desiccated soda lime diminishes degradation of desflurane to carbon monoxide and sevoflurane to compound A but does not compromise carbon dioxide absorption. Anesth Analg. 1999 Sep; 89(3):768-73. Neumann MA, Laster MJ, Weiskopf RB, Gong DH, Dudziak R, Förster H, Eger EI. PMID: 10475323.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    74. Red cell transfusion outcome studies require a prospective, randomized design. Transfusion. 1999 Jun; 39(6):657-60. Weiskopf RB. PMID: 10378848.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    75. Do we know when to transfuse red cells to treat acute anemia? Transfusion. 1998 Jun; 38(6):517-21. Weiskopf RB. PMID: 9661684.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    76. Changing from isoflurane to desflurane toward the end of anesthesia does not accelerate recovery in humans. Anesthesiology. 1998 Apr; 88(4):914-21. Neumann MA, Weiskopf RB, Gong DH, Eger EI, Ionescu P. PMID: 9579499.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    77. The effect of anesthetic duration on kinetic and recovery characteristics of desflurane versus sevoflurane, and on the kinetic characteristics of compound A, in volunteers. Anesth Analg. 1998 Feb; 86(2):414-21. Eger EI, Gong D, Koblin DD, Bowland T, Ionescu P, Laster MJ, Weiskopf RB. PMID: 9459259.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    78. Human cardiovascular and metabolic response to acute, severe isovolemic anemia. JAMA. 1998 Jan 21; 279(3):217-21. Weiskopf RB, Viele MK, Feiner J, Kelley S, Lieberman J, Noorani M, Leung JM, Fisher DM, Murray WR, Toy P, Moore MA. PMID: 9438742.
      View in: PubMed   Mentions: 66     Fields:    Translation:Humans
    79. In rats breathing from a nonrebreathing system, substitution of desflurane for isoflurane toward the end of anesthesia incompletely restores the time of recovery toward that of desflurane. Anesth Analg. 1998 Jan; 86(1):198-201. Gong DH, Weiskopf RB, Neumann MA, Laster MJ, Eger EI. PMID: 9428878.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    80. Fentanyl augments the blockade of the sympathetic response to incision (MAC-BAR) produced by desflurane and isoflurane: desflurane and isoflurane MAC-BAR without and with fentanyl. Anesthesiology. 1998 Jan; 88(1):43-9. Daniel M, Weiskopf RB, Noorani M, Eger EI. PMID: 9447854.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    81. Dehydration of Baralyme increases compound A resulting from sevoflurane degradation in a standard anesthetic circuit used to anesthetize swine. Anesth Analg. 1997 Dec; 85(6):1382-6. Steffey EP, Laster MJ, Ionescu P, Eger EI, Gong D, Weiskopf RB. PMID: 9390613.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    82. Dose-related biochemical markers of renal injury after sevoflurane versus desflurane anesthesia in volunteers. Anesth Analg. 1997 Nov; 85(5):1154-63. Eger EI, Gong D, Koblin DD, Bowland T, Ionescu P, Laster MJ, Weiskopf RB. PMID: 9356118.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    83. Quantitative differences in the production and toxicity of CF2=BrCl versus CH2F-O-C(=CF2)(CF3) (compound A): the safety of halothane does not indicate the safety of sevoflurane. Anesth Analg. 1997 Nov; 85(5):1164-70. Eger EI, Ionescu P, Laster MJ, Gong D, Weiskopf RB, Kerschmann RL. PMID: 9356119.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    84. Baralyme dehydration increases and soda lime dehydration decreases the concentration of compound A resulting from sevoflurane degradation in a standard anesthetic circuit. Anesth Analg. 1997 Oct; 85(4):892-8. Eger EI, Ionescu P, Laster MJ, Weiskopf RB. PMID: 9322476.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    85. Recovery and kinetic characteristics of desflurane and sevoflurane in volunteers after 8-h exposure, including kinetics of degradation products. Anesthesiology. 1997 Sep; 87(3):517-26. Eger EI, Bowland T, Ionescu P, Laster MJ, Fang Z, Gong D, Sonner J, Weiskopf RB. PMID: 9316955.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    86. Recombinant human hemoglobin does not affect renal function in humans: analysis of safety and pharmacokinetics. Anesthesiology. 1997 Apr; 86(4):848-58. Viele MK, Weiskopf RB, Fisher D. PMID: 9105229.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    87. Nephrotoxicity of sevoflurane versus desflurane anesthesia in volunteers. Anesth Analg. 1997 Jan; 84(1):160-8. Eger EI, Koblin DD, Bowland T, Ionescu P, Laster MJ, Fang Z, Gong D, Sonner J, Weiskopf RB. PMID: 8989018.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    88. Compound A: solubility in saline and olive oil; destruction by blood. Anesth Analg. 1996 Oct; 83(4):849-53. Eger EI, Ionescu P, Koblin DD, Weiskopf RB. PMID: 8831333.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    89. Propofol fails to attenuate the cardiovascular response to rapid increases in desflurane concentration. Anesthesiology. 1996 Jan; 84(1):75-80. Daniel M, Eger EI, Weiskopf RB, Noorani M. PMID: 8572357.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    90. Cardiovascular stimulation induced by rapid increases in desflurane concentration in humans results from activation of tracheopulmonary and systemic receptors. Anesthesiology. 1995 Dec; 83(6):1173-8. Weiskopf RB, Eger EI, Daniel M, Noorani M. PMID: 8533909.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    91. Fentanyl, clonidine, and repeated increases in desflurane concentration, but not nitrous oxide or esmolol, block the transient mydriasis caused by rapid increases in desflurane concentration. Anesth Analg. 1995 Aug; 81(2):372-8. Daniel M, Larson MD, Eger EI, Noorani M, Weiskopf RB. PMID: 7618730.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    92. Subanesthetic concentrations of desflurane and isoflurane suppress explicit and implicit learning. Anesth Analg. 1995 Mar; 80(3):568-72. Gonsowski CT, Chortkoff BS, Eger EI, Bennett HL, Weiskopf RB. PMID: 7864427.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    93. Mathematical analysis of isovolemic hemodilution indicates that it can decrease the need for allogeneic blood transfusion. Transfusion. 1995 Jan; 35(1):37-41. Weiskopf RB. PMID: 7503829.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    94. Fentanyl, esmolol, and clonidine blunt the transient cardiovascular stimulation induced by desflurane in humans. Anesthesiology. 1994 Dec; 81(6):1350-5. Weiskopf RB, Eger EI, Noorani M, Daniel M. PMID: 7992902.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    95. Repetitive rapid increases in desflurane concentration blunt transient cardiovascular stimulation in humans. Anesthesiology. 1994 Oct; 81(4):843-9. Weiskopf RB, Eger EI, Noorani M, Daniel M. PMID: 7943835.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    96. Rapid 1% increases of end-tidal desflurane concentration to greater than 5% transiently increase heart rate and blood pressure in humans. Anesthesiology. 1994 Jul; 81(1):94-8. Moore MA, Weiskopf RB, Eger EI, Noorani M, McKay L, Damask M. PMID: 8042815.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    97. What can we learn about the need for transfusion from patients who refuse blood? The experience with Jehovah's Witnesses. Transfusion. 1994 May; 34(5):396-401. Viele MK, Weiskopf RB. PMID: 8191563.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    98. Rapid increase in desflurane concentration is associated with greater transient cardiovascular stimulation than with rapid increase in isoflurane concentration in humans. Anesthesiology. 1994 May; 80(5):1035-45. Weiskopf RB, Moore MA, Eger EI, Noorani M, McKay L, Chortkoff B, Hart PS, Damask M. PMID: 8017643.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCTClinical Trials
    99. The desflurane (Tec 6) vaporizer: design, design considerations and performance evaluation. Br J Anaesth. 1994 Apr; 72(4):474-9. Weiskopf RB, Sampson D, Moore MA. PMID: 8155456.
      View in: PubMed   Mentions: 4     Fields:    
    100. Humans anesthetized with sevoflurane or isoflurane have similar arrhythmic response to epinephrine. Anesthesiology. 1994 Mar; 80(3):545-9. Navarro R, Weiskopf RB, Moore MA, Lockhart S, Eger EI, Koblin D, Lu G, Wilson C. PMID: 7511357.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    101. Sympathetic hyperactivity during desflurane anesthesia. Anesthesiology. 1994 Feb; 80(2):482-3. Eger EI, Weiskopf RB. PMID: 8311337.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    102. Comparing the costs of inhaled anesthetics. Anesthesiology. 1993 Dec; 79(6):1413-8. Weiskopf RB, Eger EI. PMID: 8068064.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    103. Arrhythmogenic doses of epinephrine are similar during desflurane or isoflurane anesthesia in humans. Anesthesiology. 1993 Nov; 79(5):943-7. Moore MA, Weiskopf RB, Eger EI, Wilson C, Lu G. PMID: 7694528.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    104. Desflurane does not produce hepatic or renal injury in human volunteers. Anesth Analg. 1992 Apr; 74(4):570-4. Weiskopf RB, Eger EI, Ionescu P, Yasuda N, Cahalan MK, Freire B, Peterson N, Lockhart SH, Rampil IJ, Laster M. PMID: 1554124.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    105. Does desflurane modify circulatory responses to stimulation in humans? Anesth Analg. 1991 Aug; 73(2):175-9. Yasuda N, Weiskopf RB, Cahalan MK, Ionescu P, Caldwell JE, Eger EI, Rampil IJ, Lockhart SH. PMID: 1854032.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    106. Cardiovascular actions of desflurane in normocarbic volunteers. Anesth Analg. 1991 Aug; 73(2):143-56. Weiskopf RB, Cahalan MK, Eger EI, Yasuda N, Rampil IJ, Ionescu P, Lockhart SH, Johnson BH, Freire B, Kelley S. PMID: 1854029.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    107. Hemodynamic effects of desflurane/nitrous oxide anesthesia in volunteers. Anesth Analg. 1991 Aug; 73(2):157-64. Cahalan MK, Weiskopf RB, Eger EI, Yasuda N, Ionescu P, Rampil IJ, Lockhart SH, Freire B, Peterson NA. PMID: 1854030.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    108. Cardiovascular actions of desflurane with and without nitrous oxide during spontaneous ventilation in humans. Anesth Analg. 1991 Aug; 73(2):165-74. Weiskopf RB, Cahalan MK, Ionescu P, Eger EI, Yasuda N, Lockhart SH, Rampil IJ, Laster M, Freire B, Peterson N. PMID: 1854031.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    109. Fluoride metabolites after prolonged exposure of volunteers and patients to desflurane. Anesth Analg. 1991 Aug; 73(2):180-5. Sutton TS, Koblin DD, Gruenke LD, Weiskopf RB, Rampil IJ, Waskell L, Eger EI. PMID: 1854033.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    110. [Solubility of desflurane (I-653), sevoflurane, isoflurane, and halothane in human blood]. Masui. 1991 Jul; 40(7):1059-62. Yasuda N, Eger EI, Weiskopf RB, Tanifuji Y, Kobayashi K. PMID: 1920779.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    111. Depression of ventilation by desflurane in humans. Anesthesiology. 1991 Mar; 74(3):484-8. Lockhart SH, Rampil IJ, Yasuda N, Eger EI, Weiskopf RB. PMID: 1900396.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    112. The neuromuscular effects of desflurane, alone and combined with pancuronium or succinylcholine in humans. Anesthesiology. 1991 Mar; 74(3):412-8. Caldwell JE, Laster MJ, Magorian T, Heier T, Yasuda N, Lynam DP, Eger EI, Weiskopf RB. PMID: 2001017.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    113. Kinetics of desflurane, isoflurane, and halothane in humans. Anesthesiology. 1991 Mar; 74(3):489-98. Yasuda N, Lockhart SH, Eger EI, Weiskopf RB, Johnson BH, Freire BA, Fassoulaki A. PMID: 2001028.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    114. Comparison of kinetics of sevoflurane and isoflurane in humans. Anesth Analg. 1991 Mar; 72(3):316-24. Yasuda N, Lockhart SH, Eger EI, Weiskopf RB, Liu J, Laster M, Taheri S, Peterson NA. PMID: 1994760.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    115. Clinical characteristics of desflurane in surgical patients: minimum alveolar concentration. Anesthesiology. 1991 Mar; 74(3):429-33. Rampil IJ, Lockhart SH, Zwass MS, Peterson N, Yasuda N, Eger EI, Weiskopf RB, Damask MC. PMID: 2001020.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    116. The electroencephalographic effects of desflurane in humans. Anesthesiology. 1991 Mar; 74(3):434-9. Rampil IJ, Lockhart SH, Eger EI, Yasuda N, Weiskopf RB, Cahalan MK. PMID: 2001021.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    117. Percutaneous loss of desflurane, isoflurane, and halothane in humans. Anesthesiology. 1991 Mar; 74(3):479-83. Fassoulaki A, Lockhart SH, Freire BA, Yasuda N, Eger EI, Weiskopf RB, Johnson BH. PMID: 2001027.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    118. Comparison of percutaneous losses of sevoflurane and isoflurane in humans. Anesth Analg. 1991 Feb; 72(2):212-5. Lockhart SH, Yasuda N, Peterson N, Laster M, Taheri S, Weiskopf RB, Eger EI. PMID: 1985506.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    119. Pharmacokinetics of desflurane, sevoflurane, isoflurane, and halothane in pigs. Anesth Analg. 1990 Oct; 71(4):340-8. Yasuda N, Targ AG, Eger EI, Johnson BH, Weiskopf RB. PMID: 2400116.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    120. Hepatocellular integrity in swine after prolonged desflurane (I-653) and isoflurane anesthesia: evaluation of plasma alanine aminotransferase activity. Anesth Analg. 1990 Sep; 71(3):249-53. Holmes MA, Weiskopf RB, Eger EI, Johnson BH, Rampil IJ. PMID: 2393108.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    121. Cardiovascular actions of common anesthetic adjuvants during desflurane (I-653) and isoflurane anesthesia in swine. Anesth Analg. 1990 Aug; 71(2):144-8. Weiskopf RB, Eger EI, Holmes MA, Yasuda N, Johnson BH, Targ AG, Rampil IJ. PMID: 2375516.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    122. Washin and washout of isoflurane administered via bubble oxygenators during hypothermic cardiopulmonary bypass. Anesthesiology. 1989 Oct; 71(4):519-25. Nussmeier NA, Lambert ML, Moskowitz GJ, Cohen NH, Weiskopf RB, Fisher DM, Eger EI. PMID: 2802209.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    123. Cardiovascular safety and actions of high concentrations of I-653 and isoflurane in swine. Anesthesiology. 1989 May; 70(5):793-8. Weiskopf RB, Holmes MA, Rampil IJ, Johnson BH, Yasuda N, Targ AG, Eger EI. PMID: 2719313.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    124. Epinephrine-induced premature ventricular contractions and changes in arterial blood pressure and heart rate during I-653, isoflurane, and halothane anesthesia in swine. Anesthesiology. 1989 Feb; 70(2):293-8. Weiskopf RB, Eger EI, Holmes MA, Rampil IJ, Johnson B, Brown JG, Yasuda N, Targ AG. PMID: 2464293.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    125. Metabolism of I-653 and isoflurane in swine. Anesth Analg. 1989 Feb; 68(2):147-9. Koblin DD, Weiskopf RB, Holmes MA, Konopka K, Rampil IJ, Eger EI, Waskell L. PMID: 2913848.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    126. Minimum alveolar concentration of I-653 and isoflurane in pigs: definition of a supramaximal stimulus. Anesth Analg. 1988 Dec; 67(12):1174-6. Eger EI, Johnson BH, Weiskopf RB, Holmes MA, Yasuda N, Targ A, Rampil IJ. PMID: 3195734.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    127. In vitro anesthetic washin and washout via bubble oxygenators: influence of anesthetic solubility and rates of carrier gas inflow and pump blood flow. Anesth Analg. 1988 Oct; 67(10):982-7. Nussmeier NA, Moskowitz GJ, Weiskopf RB, Cohen NH, Fisher DM, Eger EI. PMID: 3048150.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    128. Cardiovascular effects of I653 in swine. Anesthesiology. 1988 Sep; 69(3):303-9. Weiskopf RB, Holmes MA, Eger EI, Johnson BH, Rampil IJ, Brown JG. PMID: 3415011.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    129. I653 and isoflurane produce similar dose-related changes in the electroencephalogram of pigs. Anesthesiology. 1988 Sep; 69(3):298-302. Rampil IJ, Weiskopf RB, Brown JG, Eger EI, Johnson BH, Holmes MA, Donegan JH. PMID: 3415010.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    130. Cardiovascular and metabolic sequelae of inducing anesthesia with ketamine or thiopental in hypovolemic swine. Anesthesiology. 1984 Mar; 60(3):214-9. Weiskopf RB, Bogetz MS, Roizen MF, Reid IA. PMID: 6696255.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    131. The absence of an effect of halothane on blood hemoglobin O 2 equilibrium in vitro. Anesthesiology. 1971 Dec; 35(6):579-81. Weiskopf RB, Nishimura M, Severinghaus JW. PMID: 5124738.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
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