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Michael Waterfield, MD, PhD

TitleAssistant Professor
InstitutionUniversity of California San Francisco
DepartmentPediatrics
Address513 Parnassus Ave
San Francisco CA 94143
Phone415-502-9581
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    Collapse Biography 
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    University of California, San FranciscoResidency

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    Dr. Waterfield is originally from Baltimore, MD, and attended Bowdoin College in Brunswick, ME. After taking several years off to carry out research at the University of California, San Diego, he completed an MD/PhD at Penn State College of Medicine. Dr. Waterfield’s PhD work was in the lab of Dr. Shao-Cong Sun, where he studied signal transduction in macrophages. After completing his MD, he moved to UCSF for residency training and a pediatric rheumatology fellowship.


    Collapse Research 
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    Coopting epigenetic regulators by Aire to maintain immune tolerance
    NIH/NIAID K08AI121513Feb 1, 2016 - Jan 31, 2021
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. LaFlam TN, Seumois G, Miller CN, Lwin W, Fasano KJ, Waterfield M, Proekt I, Vijayanand P, Anderson MS. Identification of a novel cis-regulatory element essential for immune tolerance. J Exp Med. 2015 Nov 16; 212(12):1993-2002. PMID: 26527800; PMCID: PMC4647269.
      View in: PubMed, PubMed Central
    2. Watkin LB, Jessen B, Wiszniewski W, Vece TJ, Jan M, Sha Y, Thamsen M, Santos-Cortez RL, Lee K, Gambin T, Forbes LR, Law CS, Stray-Pedersen A, Cheng MH, Mace EM, Anderson MS, Liu D, Tang LF, Nicholas SK, Nahmod K, Makedonas G, Canter DL, Kwok PY, Hicks J, Jones KD, Penney S, Jhangiani SN, Rosenblum MD, Dell SD, Waterfield M, Papa FR, Muzny DM, Zaitlen N, Leal SM, Gonzaga-Jauregui C. COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis. Nat Genet. 2015 Jun; 47(6):654-60. PMID: 25894502; PMCID: PMC4513663.
      View in: PubMed, PubMed Central
    3. Waterfield M, Khan IS, Cortez JT, Fan U, Metzger T, Greer A, Fasano K, Martinez-Llordella M, Pollack JL, Erle DJ, Su M, Anderson MS. The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance. Nat Immunol. 2014 Mar; 15(3):258-65. PMID: 24464130; PMCID: PMC4172453.
      View in: PubMed, PubMed Central
    4. Waterfield M, Anderson MS. Autoimmunity's collateral damage: Immunodeficiency hints at autoreactivity to cytokines. Nat Med. 2011 Sep 07; 17(9):1054-5. PMID: 21900922.
      View in: PubMed
    5. Waterfield M, Anderson MS. Clues to immune tolerance: the monogenic autoimmune syndromes. Ann N Y Acad Sci. 2010 Dec; 1214:138-55. PMID: 20969580; PMCID: PMC3010261.
      View in: PubMed, PubMed Central
    6. Waterfield M, Zhang M, Norman LP, Sun SC. NF-kappaB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase. Mol Cell. 2003 Mar; 11(3):685-94. PMID: 12667451.
      View in: PubMed
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