Maria Dall'Era, MD

InstitutionUniversity of California San Francisco
Address533 Parnassus Avenue
San Francisco CA 94117
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency School of Medicine
    University of California, San FranciscoM.D.1997School of Medicine

    Collapse Overview 
    Collapse Overview
    Maria Dall’Era, M.D. is associate professor of clinical medicine in the Division of Rheumatology. Within rheumatology, her subspecialty is systemic lupus erythematosus (SLE). Dr. Dall’Era is the director of the UCSF Lupus Clinic in which she cares for > 200 patients with SLE. She has recently established an SLE Transition Clinic with Dr. Emily von Scheven with the goal of improving the process of transition between pediatric and adult care. She is also director of the Rheumatology Clinical Research Center in which she oversees the conduct of various clinical trials and observational research studies, and she is the UCSF Center Director for the Lupus Clinical Trials Consortium. Her research program is focused on three major areas: (1) the design and conduct of clinical trials of novel biologic agents for SLE and lupus nephritis, (2) a population-based SLE epidemiologic project funded by the Centers of Disease Control and Prevention and the California Department of Public Health with the goal of determining contemporary, accurate estimates of the incidence and prevalence of SLE in San Francisco County, and (3) a project in conjunction with the Lupus Nephritis Trials Network to determine the most appropriate renal outcome measures that should be utilized in lupus nephritis clinical trials.

    Dr. Dall’Era is also very involved with the education of trainees, both in the outpatient clinical arena, inpatient setting, and in the medical school. With a grant from the American College of Rheumatology’s Lupus Initiative, she created two pilot, interactive, on-line, virtual simulation SLE cases in collaboration with Dr. Michelle Lin. She incorporated novel features into the cases including a “differential diagnosis slider” in which the learner is required to re-adjust their differential diagnosis after case content is revealed. She currently has a grant from the American College of Rheumatology to develop additional interactive rheumatologic cases for the medical students using a mobile application platform. These cases will be utilized in the I3 section for the second year medical students. Lastly, Dr. Dall’Era is active in the education of practicing physicians and is the San Francisco lead for the National Health Education Program on Lupus for Healthcare Providers.

    Collapse Research 
    Collapse Research Activities and Funding
    Racial/ethnic and socioeconomic disparities in biologic and clinical SLE outcomes
    CDC/NCCDPHP U01DP005120Sep 1, 2014 - Aug 31, 2019
    Role: Principal Investigator

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    Collapse Clinical Trials
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Merrill JT, Manzi S, Aranow C, Askenase A, Bruce I, Chakravarty E, Chong B, Costenbader K, Dall'Era M, Ginzler E, Hanrahan L, Kalunian K, Merola J, Raymond S, Rovin B, Saxena A, Werth VP. Lupus community panel proposals for optimising clinical trials: 2018. Lupus Sci Med. 2018; 5(1):e000258. PMID: 29657738.
      View in: PubMed
    2. Dall'Era M, Cisternas MG, Snipes K, Herrinton LJ, Gordon C, Helmick CG. The Incidence and Prevalence of Systemic Lupus Erythematosus in San Francisco County, California: The California Lupus Surveillance Project. Arthritis Rheumatol. 2017 10; 69(10):1996-2005. PMID: 28891237.
      View in: PubMed
    3. Dall'Era M. Treatment of lupus nephritis: current paradigms and emerging strategies. Curr Opin Rheumatol. 2017 May; 29(3):241-247. PMID: 28207493.
      View in: PubMed
    4. Aranow C, Kamen DL, Dall'Era M, Massarotti EM, Mackay MC, Koumpouras F, Coca A, Chatham WW, Clowse ME, Criscione-Schreiber LG, Callahan S, Goldmuntz EA, Keyes-Elstein L, Oswald M, Gregersen PK, Diamond B. Randomized, Double-Blind, Placebo-Controlled Trial of the Effect of Vitamin D3 on the Interferon Signature in Patients With Systemic Lupus Erythematosus. Arthritis Rheumatol. 2015 Jul; 67(7):1848-57. PMID: 25777546; PMCID: PMC4732716.
    5. Dall'Era M, Levesque V, Solomons N, Truman M, Wofsy D. Identification of clinical and serological factors during induction treatment of lupus nephritis that are associated with renal outcome. Lupus Sci Med. 2015; 2(1):e000089. PMID: 26023331; PMCID: PMC4442174.
    6. Dall'Era M, Cisternas MG, Smilek DE, Straub L, Houssiau FA, Cervera R, Rovin BH, Mackay M. Predictors of long-term renal outcome in lupus nephritis trials: lessons learned from the Euro-Lupus Nephritis cohort. Arthritis Rheumatol. 2015 May; 67(5):1305-13. PMID: 25605554.
      View in: PubMed
    7. Ashouri JF, Davis JL, Farkas A, Durack JC, Ramachandran R, Dall'Era M. A young woman with systemic lupus erythematosus and extensive mesenteric vasculitis involving small and medium vessels. Arthritis Care Res (Hoboken). 2012 Dec; 64(12):1928-33. PMID: 22933330.
      View in: PubMed
    8. Dall'Era M. Mycophenolate mofetil in the treatment of systemic lupus erythematosus. Curr Opin Rheumatol. 2011 Sep; 23(5):454-8. PMID: 21720247.
      View in: PubMed
    9. Dall'era M, Chakravarty EF. Treatment of mild, moderate, and severe lupus erythematosus: focus on new therapies. Curr Rheumatol Rep. 2011 Aug; 13(4):308-16. PMID: 21584692; PMCID: PMC4400849.
    10. Yazdany J, Trupin L, Gansky SA, Dall'era M, Yelin EH, Criswell LA, Katz PP. Brief index of lupus damage: a patient-reported measure of damage in systemic lupus erythematosus. Arthritis Care Res (Hoboken). 2011 Aug; 63(8):1170-7. PMID: 21584946; PMCID: PMC3149719.
    11. Dall'Era M, Stone D, Levesque V, Cisternas M, Wofsy D. Identification of biomarkers that predict response to treatment of lupus nephritis with mycophenolate mofetil or pulse cyclophosphamide. Arthritis Care Res (Hoboken). 2011 Mar; 63(3):351-7. PMID: 21080348.
      View in: PubMed
    12. Dillon SR, Harder B, Lewis KB, Moore MD, Liu H, Bukowski TR, Hamacher NB, Lantry MM, Maurer M, Krejsa CM, Ellsworth JL, Pederson S, Elkon KB, Wener MH, Dall'Era M, Gross JA. B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin. Arthritis Res Ther. 2010; 12(2):R48. PMID: 20302641; PMCID: PMC2888197.
    13. Dall'Era M, Wofsy D. Connective tissue diseases: Belimumab for systemic lupus erythematosus: breaking through? Nat Rev Rheumatol. 2010 Mar; 6(3):124-5. PMID: 20197774.
      View in: PubMed
    14. Dall'Era M, Wofsy D. Biologic therapy for systemic lupus erythematosus. Discov Med. 2010 Jan; 9(44):20-3. PMID: 20102681.
      View in: PubMed
    15. Dall'Era M, Wofsy D. Systemic lupus erythematosus clinical trials-an interim analysis. Nat Rev Rheumatol. 2009 Jun; 5(6):348-51. PMID: 19491915.
      View in: PubMed
    16. Dall'Era M, Chakravarty E, Wallace D, Genovese M, Weisman M, Kavanaugh A, Kalunian K, Dhar P, Vincent E, Pena-Rossi C, Wofsy D. Reduced B lymphocyte and immunoglobulin levels after atacicept treatment in patients with systemic lupus erythematosus: results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating trial. Arthritis Rheum. 2007 Dec; 56(12):4142-50. PMID: 18050206.
      View in: PubMed
    17. Gillis JZ, Dall'era M, Gross A, Yazdany J, Davis J. Six refractory lupus patients treated with rituximab: a case series. Arthritis Rheum. 2007 Apr 15; 57(3):538-42. PMID: 17394185.
      View in: PubMed
    18. Dall'Era M, Wofsy D. Clinical trial design in systemic lupus erythematosus. Curr Opin Rheumatol. 2006 Sep; 18(5):476-80. PMID: 16896285.
      View in: PubMed
    19. Dall'Era M, Davis JC. Systemic lupus erythematosus. How to manage, when to refer. Postgrad Med. 2003 Nov; 114(5):31-7, 40. PMID: 14650091.
      View in: PubMed