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Stephen Hauser, MD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentNeurology
Address675 Nelson Rising Lane
San Francisco CA 94158
Phone415-476-9211
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    Other Positions
    TitleDirector, UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Education and Training
    Harvard UniversityM.D.1975School of Medicine
    Collapse Awards and Honors
    A. Alfred Taubman Medical Research Institute2017Taubman Prize
    Multiple Sclerosis International Foundation2013Charcot Award
    President Barack Obama2010Appointed Member, Presidential Commission for the Study of Bioethical Issues
    ISNI Conference 2010, Spain2010The Dale McFarlin Memorial Lecture
    National Academy of Sciences2009  - 2011Chair, Committee on Gulf War and Health, Institute of Medicine
    National Multiple Sclerosis Society and the American Academy of Neurology2008John Dystel Prize for Multiple Sclerosis Research
    National Academy of Sciences1991  - 1998Javits Neuroscience Investigator, National Institute of Health

    Collapse Overview 
    Collapse Overview
    Stephen L. Hauser, M.D. is a graduate of MIT (Phi Beta Kappa) and Harvard Medical School (Magna Cum Laude). He trained in internal medicine at the New York Hospital-Cornell Medical Center, in neurology at the Massachusetts General Hospital (MGH), and in immunology at Harvard Medical School and the Institute Pasteur in Paris, France, and was a faculty member at Harvard Medical School before moving to UCSF in 1992. A neuroimmunologist, Dr. Hauser's research has advanced our understanding of the genetic basis, immune mechanisms, and treatment of multiple sclerosis. Dr. Hauser is a fellow of the American Academy of Arts and Sciences and the American Academy of Physicians, a member of the Institute of Medicine of the National Academy of Sciences (previous Chair of Section 7 and former Chair of the Committee on Gulf War and Health Outcomes), an editor of the textbook Harrison's Principles of Internal Medicine, and former editor-in-chief of Annals of Neurology (2005-2014). He has served as President of the American Neurological Association and President of the Medical Staff at UCSF. He also serves on several scientific advisory boards for nonprofit organizations. Dr. Hauser has received numerous awards and honors for his work, including the Jacob Javits Neuroscience Investigator Award, the 2008 John Dystel Prize for Multiple Sclerosis Research, and the 2013 Charcot Award.

    In April, 2010 Dr. Hauser was appointed by President Obama to the Presidential Commission for the Study of Bioethical Issues charged with advising the President on issues that may emerge from advances in biomedicine and related areas of science and technology.

    In 2016, Dr. Hauser was appointed as Director of the new UCSF Weill Institute for Neurosciences. In this role he will bring together a cross-disciplinary alliance of nearly 100 UCSF faculty members from 15 basic-science departments to solve some of the most complex challenges in the human brain.


    Collapse Research 
    Collapse Research Activities and Funding
    Disease relevance of CD20 expression on T cells in multiple sclerosis patients
    NIH/NINDS R01NS092835Aug 15, 2015 - Jun 30, 2020
    Role: Principal Investigator
    Establishment of a Core DNA Repository for Multiple Sclerosis
    National Multiple Sclerosis Society RG 2899-D11Jul 1, 2012 - Jun 30, 2017
    Role: Co-Principal Investigator
    Educating Physician-Neuroscientists: The R25 at UCSF
    NIH/NINDS R25NS070680Apr 1, 2010 - Jun 30, 2020
    Role: Principal Investigator
    Molecular Genetics of HLA and Disease
    NIH/NIAID U19AI067152Sep 1, 2005 - Feb 28, 2011
    Role: Principal Investigator
    A Haplotype Map for Multiple Sclerosis
    NIH/NINDS R01NS049477Jul 1, 2004 - May 31, 2015
    Role: Principal Investigator
    ANNUAL MRI, MTR AND HMRSI IN HEALTHY CONTROLS AND PPMS
    NIH/NINDS R01NS039529Aug 1, 2000 - Sep 30, 2003
    Role: Principal Investigator
    Mechanisms of EAE
    NIH/NIAID R01AI043073Jun 1, 1992 - Feb 28, 2009
    Role: Co-Principal Investigator
    MECHANISMS OF EAE
    NIH/NINDS R01NS030727Jun 1, 1992 - Aug 31, 1996
    Role: Principal Investigator
    Gene linkage study of multiple sclerosis sibling pairs
    NIH/NINDS R01NS026799Dec 1, 1988 - Jul 31, 2019
    Role: Principal Investigator
    NEURITE-PROMOTING FACTORS FROM MUSCLE AND AUTOIMMUNITY
    NIH/NINDS R01NS023816Aug 1, 1986 - Jul 31, 1989
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Global Health
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Wolinsky JS, Montalban X, Hauser SL, Giovannoni G, Vermersch P, Bernasconi C, Deol-Bhullar G, Garren H, Chin P, Belachew S, Kappos L. Evaluation of no evidence of progression or active disease (NEPAD) in patients with primary progressive multiple sclerosis in the ORATORIO trial. Ann Neurol. 2018 Aug 29. PMID: 30155979.
      View in: PubMed
    2. Bove R, Bevan C, Crabtree E, Zhao C, Gomez R, Garcha P, Morrissey J, Dierkhising J, Green AJ, Hauser SL, Cree BA, Wallin MT, Gelfand JM. Toward a low-cost, in-home, telemedicine-enabled assessment of disability in multiple sclerosis. Mult Scler. 2018 Aug 24; 1352458518793527. PMID: 30141729.
      View in: PubMed
    3. Regev K, Healy BC, Paul A, Diaz-Cruz C, Mazzola MA, Raheja R, Glanz BI, Kivisäkk P, Chitnis T, Jagodic M, Piehl F, Olsson T, Khademi M, Hauser S, Oksenberg J, Khoury SJ, Weiner HL, Gandhi R. Identification of MS-specific serum miRNAs in an international multicenter study. Neurol Neuroimmunol Neuroinflamm. 2018 Sep; 5(5):e491. PMID: 30175165.
      View in: PubMed
    4. Jia X, Madireddy L, Caillier S, Santaniello A, Esposito F, Comi G, Stuve O, Zhou Y, Taylor B, Kilpatrick T, Martinelli-Boneschi F, Cree BAC, Oksenberg JR, Hauser SL, Baranzini SE. Genome sequencing uncovers phenocopies in primary progressive multiple sclerosis. Ann Neurol. 2018 Jun 16. PMID: 29908077.
      View in: PubMed
    5. Pröbstel AK, Hauser SL. Multiple Sclerosis: B Cells Take Center Stage. J Neuroophthalmol. 2018 Mar 20. PMID: 29561328.
      View in: PubMed
    6. Das G, Damotte V, Gelfand JM, Bevan C, Cree BAC, Do L, Green AJ, Hauser SL, Bove R. Rituximab before and during pregnancy: A systematic review, and a case series in MS and NMOSD. Neurol Neuroimmunol Neuroinflamm. 2018 May; 5(3):e453. PMID: 29564373.
      View in: PubMed
    7. Havrdová E, Arnold DL, Bar-Or A, Comi G, Hartung HP, Kappos L, Lublin F, Selmaj K, Traboulsee A, Belachew S, Bennett I, Buffels R, Garren H, Han J, Julian L, Napieralski J, Hauser SL, Giovannoni G. No evidence of disease activity (NEDA) analysis by epochs in patients with relapsing multiple sclerosis treated with ocrelizumab vs interferon beta-1a. Mult Scler J Exp Transl Clin. 2018 Jan-Mar; 4(1):2055217318760642. PMID: 29568544.
      View in: PubMed
    8. Canto E, Isobe N, Didonna A. Aberrant STAT phosphorylation signaling in peripheral blood mononuclear cells from multiple sclerosis patients. J Neuroinflammation. 2018 Mar 07; 15(1):72. PMID: 29514694.
      View in: PubMed
    9. Azevedo CJ, Cen SY, Khadka S, Liu S, Kornak J, Shi Y, Zheng L, Hauser SL, Pelletier D. Thalamic atrophy in multiple sclerosis: A magnetic resonance imaging marker of neurodegeneration throughout disease. Ann Neurol. 2018 Feb; 83(2):223-234. PMID: 29328531.
      View in: PubMed
    10. Sabatino JJ, Zamvil SS, Hauser SL. B-Cell Therapies in Multiple Sclerosis. Cold Spring Harb Perspect Med. 2018 Jan 22. PMID: 29358322.
      View in: PubMed
    11. Damotte V, Lizée A, Tremblay M, Agrawal A, Khankhanian P, Santaniello A, Gomez R, Lincoln R, Tang W, Chen T, Lee N, Villoslada P, Hollenbach JA, Bevan CD, Graves J, Bove R, Goodin DS, Green AJ, Baranzini SE, Cree BA, Henry RG, Hauser SL, Gelfand JM, Gourraud PA. Harnessing electronic medical records to advance research on multiple sclerosis. Mult Scler. 2018 Jan 01; 1352458517747407. PMID: 29310490.
      View in: PubMed
    12. Greenfield AL, Hauser SL. B-cell Therapy for Multiple Sclerosis: Entering an era. Ann Neurol. 2018 Jan; 83(1):13-26. PMID: 29244240.
      View in: PubMed
    13. Graves JS, Henry RG, Cree BAC, Lambert-Messerlian G, Greenblatt RM, Waubant E, Cedars MI, Zhu A. Ovarian aging is associated with gray matter volume and disability in women with MS. Neurology. 2018 Jan 16; 90(3):e254-e260. PMID: 29273686.
      View in: PubMed
    14. Bove RM, Hauser SL. Diagnosing multiple sclerosis: art and science. Lancet Neurol. 2018 Feb; 17(2):109-111. PMID: 29275980.
      View in: PubMed
    15. Bischof A, Caverzasi E, Cordano C, Hauser SL, Henry RG. Advances in Imaging Multiple Sclerosis. Semin Neurol. 2017 Oct; 37(5):538-545. PMID: 29207413.
      View in: PubMed
    16. Eggers EL, Michel BA, Wu H, Wang SZ, Bevan CJ, Abounasr A, Pierson NS, Bischof A, Kazer M, Leitner E, Greenfield AL, Demuth S, Wilson MR, Henry RG, Cree BA, Hauser SL, von Büdingen HC. Clonal relationships of CSF B cells in treatment-naive multiple sclerosis patients. JCI Insight. 2017 Nov 16; 2(22). PMID: 29202449.
      View in: PubMed
    17. Gelfand JM, Bradshaw MJ, Stern BJ, Clifford DB, Wang Y, Cho TA, Koth LL, Hauser SL, Dierkhising J, Vu N, Sriram S, Moses H, Bagnato F, Kaufmann JA, Ammah DJ, Yohannes TH, Hamblin MJ, Venna N, Green AJ, Pawate S. Infliximab for the treatment of CNS sarcoidosis: A multi-institutional series. Neurology. 2017 Oct 13. PMID: 29030454.
      View in: PubMed
    18. Green AJ, Gelfand JM, Cree BA, Bevan C, Boscardin WJ, Mei F, Inman J, Arnow S, Devereux M, Abounasr A, Nobuta H, Zhu A, Friessen M, Gerona R, von Büdingen HC, Henry RG, Hauser SL, Chan JR. Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial. Lancet. 2017 Dec 02; 390(10111):2481-2489. PMID: 29029896.
      View in: PubMed
    19. Gelfand JM, Cree BAC, Hauser SL. Ocrelizumab and Other CD20+ B-Cell-Depleting Therapies in Multiple Sclerosis. Neurotherapeutics. 2017 Oct; 14(4):835-841. PMID: 28695471.
      View in: PubMed
    20. Cekanaviciute E, Yoo BB, Runia TF, Debelius JW, Singh S, Nelson CA, Kanner R, Bencosme Y, Lee YK, Hauser SL, Crabtree-Hartman E, Sand IK, Gacias M, Zhu Y, Casaccia P, Cree BAC, Knight R, Mazmanian SK, Baranzini SE. Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models. Proc Natl Acad Sci U S A. 2017 Oct 03; 114(40):10713-10718. PMID: 28893978.
      View in: PubMed
    21. Bove R, Chitnis T, Cree BA, Tintoré M, Naegelin Y, Uitdehaag BM, Kappos L, Khoury SJ, Montalban X, Hauser SL, Weiner HL. SUMMIT (Serially Unified Multicenter Multiple Sclerosis Investigation): creating a repository of deeply phenotyped contemporary multiple sclerosis cohorts. Mult Scler. 2017 Aug 01; 1352458517726657. PMID: 28847219.
      View in: PubMed
    22. Hauser SL, VanLeeuwen J-E.STAT [editorial]. 3 ways the VA can usher in the future of health care and research. 2017.
    23. Hauser SL, Belachew S, Kappos L. Ocrelizumab in Primary Progressive and Relapsing Multiple Sclerosis. N Engl J Med. 2017 04 27; 376(17):1694. PMID: 28445661.
      View in: PubMed
    24. Montalban X, Hauser SL, Kappos L, Arnold DL, Bar-Or A, Comi G, de Seze J, Giovannoni G, Hartung HP, Hemmer B, Lublin F, Rammohan KW, Selmaj K, Traboulsee A, Sauter A, Masterman D, Fontoura P, Belachew S, Garren H, Mairon N, Chin P, Wolinsky JS. Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis. N Engl J Med. 2017 01 19; 376(3):209-220. PMID: 28002688.
      View in: PubMed
    25. Hauser SL, Bar-Or A, Comi G, Giovannoni G, Hartung HP, Hemmer B, Lublin F, Montalban X, Rammohan KW, Selmaj K, Traboulsee A, Wolinsky JS, Arnold DL, Klingelschmitt G, Masterman D, Fontoura P, Belachew S, Chin P, Mairon N, Garren H, Kappos L. Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis. N Engl J Med. 2017 01 19; 376(3):221-234. PMID: 28002679.
      View in: PubMed
    26. von Büdingen HC, Bischof A, Eggers EL, Wang S, Bevan CJ, Cree BA, Henry RG, Hauser SL. Onset of secondary progressive MS after long-term rituximab therapy - a case report. Ann Clin Transl Neurol. 2017 Jan; 4(1):46-52. PMID: 28078314.
      View in: PubMed
    27. Long-term evolution of multiple sclerosis disability in the treatment era. Ann Neurol. 2016 Oct; 80(4):499-510. PMID: 27464262.
      View in: PubMed
    28. George MF, Briggs FB, Shao X, Gianfrancesco MA, Kockum I, Harbo HF, Celius EG, Bos SD, Hedström A, Shen L, Bernstein A, Alfredsson L, Hillert J, Olsson T, Patsopoulos NA, De Jager PL, Oturai AB, Søndergaard HB, Sellebjerg F, Sorensen PS, Gomez R, Caillier SJ, Cree BA, Oksenberg JR, Hauser SL, D'Alfonso S, Leone MA, Martinelli Boneschi F, Sorosina M, van der Mei I, Taylor BV, Zhou Y, Schaefer C, Barcellos LF. Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies. Neurol Genet. 2016 Aug; 2(4):e87. PMID: 27540591; PMCID: PMC4974846.
    29. Isobe N, Keshavan A, Gourraud PA, Zhu AH, Datta E, Schlaeger R, Caillier SJ, Santaniello A, Lizée A, Himmelstein DS, Baranzini SE, Hollenbach J, Cree BA, Hauser SL, Oksenberg JR, Henry RG. Association of HLA Genetic Risk Burden With Disease Phenotypes in Multiple Sclerosis. JAMA Neurol. 2016 Jul 01; 73(7):795-802. PMID: 27244296.
      View in: PubMed
    30. Keshavan A, Paul F, Beyer MK, Zhu AH, Papinutto N, Shinohara RT, Stern W, Amann M, Bakshi R, Bischof A, Carriero A, Comabella M, Crane JC, D'Alfonso S, Demaerel P, Dubois B, Filippi M, Fleischer V, Fontaine B, Gaetano L, Goris A, Graetz C, Gröger A, Groppa S, Hafler DA, Harbo HF, Hemmer B, Jordan K, Kappos L, Kirkish G, Llufriu S, Magon S, Martinelli-Boneschi F, McCauley JL, Montalban X, Mühlau M, Pelletier D, Pattany PM, Pericak-Vance M, Cournu-Rebeix I, Rocca MA, Rovira A, Schlaeger R, Saiz A, Sprenger T, Stecco A, Uitdehaag BMJ, Villoslada P, Wattjes MP, Weiner H, Wuerfel J, Zimmer C, Zipp F. Power estimation for non-standardized multisite studies. Neuroimage. 2016 07 01; 134:281-294. PMID: 27039700.
      View in: PubMed
    31. Khankhanian P, Cozen W, Himmelstein DS, Madireddy L, Din L, van den Berg A, Matsushita T, Glaser SL, Moré JM, Smedby KE, Baranzini SE, Mack TM, Lizée A, de Sanjosé S, Gourraud PA, Nieters A, Hauser SL, Cocco P, Maynadié M, Foretová L, Staines A, Delahaye-Sourdeix M, Li D, Bhatia S, Melbye M, Onel K, Jarrett R, McKay JD, Oksenberg JR, Hjalgrim H. Meta-analysis of genome-wide association studies reveals genetic overlap between Hodgkin lymphoma and multiple sclerosis. Int J Epidemiol. 2016 06; 45(3):728-40. PMID: 26971321; PMCID: PMC5005944.
    32. Didonna A, Isobe N, Caillier SJ, Li KH, Burlingame AL, Hauser SL, Baranzini SE, Patsopoulos NA, Oksenberg JR. A non-synonymous single-nucleotide polymorphism associated with multiple sclerosis risk affects the EVI5 interactome. Hum Mol Genet. 2015 Dec 15; 24(24):7151-8. PMID: 26433934; PMCID: PMC5007634 [Available on 12/15/16].
    33. Moutsianas L, Jostins L, Beecham AH, Dilthey AT, Xifara DK, Ban M, Shah TS, Patsopoulos NA, Alfredsson L, Anderson CA, Attfield KE, Baranzini SE, Barrett J, Binder TMC, Booth D, Buck D, Celius EG, Cotsapas C, D'Alfonso S, Dendrou CA, Donnelly P, Dubois B, Fontaine B, Fugger L, Goris A, Gourraud PA, Graetz C, Hemmer B, Hillert J. Class II HLA interactions modulate genetic risk for multiple sclerosis. Nat Genet. 2015 Oct; 47(10):1107-1113. PMID: 26343388.
      View in: PubMed
    34. Schlaeger R, Papinutto N, Zhu AH, Lobach IV, Bevan CJ, Bucci M, Castellano A, Gelfand JM, Graves JS, Green AJ, Jordan KM, Keshavan A, Panara V, Stern WA, von Büdingen HC, Waubant E, Goodin DS, Cree BA, Hauser SL, Henry RG. Association Between Thoracic Spinal Cord Gray Matter Atrophy and Disability in Multiple Sclerosis. JAMA Neurol. 2015 Aug; 72(8):897-904. PMID: 26053119.
      View in: PubMed
    35. Khankhanian P, Matsushita T, Madireddy L, Lizée A, Din L, Moré JM, Gourraud PA, Hauser SL, Baranzini SE, Oksenberg JR. Genetic contribution to multiple sclerosis risk among Ashkenazi Jews. BMC Med Genet. 2015 Jul 28; 16:55. PMID: 26212423; PMCID: PMC4557862.
    36. Tranah GJ, Santaniello A, Caillier SJ, D'Alfonso S, Martinelli Boneschi F, Hauser SL, Oksenberg JR. Mitochondrial DNA sequence variation in multiple sclerosis. Neurology. 2015 Jul 28; 85(4):325-30. PMID: 26136518; PMCID: PMC4520811.
    37. Hauser SL. Advancing ethical neuroscience. Ann Neurol. 2015 May; 77(5):735-7. PMID: 25820329.
      View in: PubMed
    38. Isobe N, Madireddy L, Khankhanian P, Matsushita T, Caillier SJ, Moré JM, Gourraud PA, McCauley JL, Beecham AH. An ImmunoChip study of multiple sclerosis risk in African Americans. Brain. 2015 Jun; 138(Pt 6):1518-30. PMID: 25818868; PMCID: PMC4553906.
    39. Papinutto N, Schlaeger R, Panara V, Zhu AH, Caverzasi E, Stern WA, Hauser SL, Henry RG. Age, gender and normalization covariates for spinal cord gray matter and total cross-sectional areas at cervical and thoracic levels: A 2D phase sensitive inversion recovery imaging study. PLoS One. 2015; 10(3):e0118576. PMID: 25781178; PMCID: PMC4363673.
    40. Hauser SL. Hematopoietic stem cell transplantation for MS: extraordinary evidence still needed. JAMA. 2015 Jan 20; 313(3):251-2. PMID: 25602994.
      View in: PubMed
    41. Goyette P, Boucher G, Mallon D, Ellinghaus E, Jostins L, Huang H, Ripke S, Gusareva ES, Annese V, Hauser SL, Oksenberg JR, Thomsen I, Leslie S. High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis. Nat Genet. 2015 Feb; 47(2):172-9. PMID: 25559196.
      View in: PubMed
    42. Papinutto N, Schlaeger R, Panara V, Caverzasi E, Ahn S, Johnson KJ, Zhu AH, Stern WA, Laub G, Hauser SL, Henry RG. 2D phase-sensitive inversion recovery imaging to measure in vivo spinal cord gray and white matter areas in clinically feasible acquisition times. J Magn Reson Imaging. 2015 Sep; 42(3):698-708. PMID: 25483607.
      View in: PubMed
    43. Hauser SL. The Charcot Lecture | beating MS: a story of B cells, with twists and turns. Mult Scler. 2015 Jan; 21(1):8-21. PMID: 25480864; PMCID: PMC4580247.
    44. Gourraud PA, Henry RG, Cree BA, Crane JC, Lizee A, Olson MP, Santaniello AV, Datta E, Zhu AH, Bevan CJ, Gelfand JM, Graves JS, Goodin DS, Green AJ, von Büdingen HC, Waubant E, Zamvil SS, Crabtree-Hartman E, Nelson S, Baranzini SE, Hauser SL. Precision medicine in chronic disease management: The multiple sclerosis BioScreen. Ann Neurol. 2014 Nov; 76(5):633-42. PMID: 25263997; PMCID: PMC4214886.
    45. Schlaeger R, Papinutto N, Panara V, Bevan C, Lobach IV, Bucci M, Caverzasi E, Gelfand JM, Green AJ, Jordan KM, Stern WA, von Büdingen HC, Waubant E, Zhu AH, Goodin DS, Cree BA, Hauser SL, Henry RG. Spinal cord gray matter atrophy correlates with multiple sclerosis disability. Ann Neurol. 2014 Oct; 76(4):568-80. PMID: 25087920.
      View in: PubMed
    46. Palanichamy A, Apeltsin L, Kuo TC, Sirota M, Wang S, Pitts SJ, Sundar PD, Telman D, Zhao LZ, Derstine M, Abounasr A, Hauser SL, von Büdingen HC. Immunoglobulin class-switched B cells form an active immune axis between CNS and periphery in multiple sclerosis. Sci Transl Med. 2014 Aug 06; 6(248):248ra106. PMID: 25100740; PMCID: PMC4176763.
    47. Azevedo CJ, Kornak J, Chu P, Sampat M, Okuda DT, Cree BA, Nelson SJ, Hauser SL, Pelletier D. In vivo evidence of glutamate toxicity in multiple sclerosis. Ann Neurol. 2014 Aug; 76(2):269-78. PMID: 25043416; PMCID: PMC4142752.
    48. Mei F, Fancy SPJ, Shen YA, Niu J, Zhao C, Presley B, Miao E, Lee S, Mayoral SR, Redmond SA, Etxeberria A, Xiao L, Franklin RJM, Green A, Hauser SL, Chan JR. Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis. Nat Med. 2014 Aug; 20(8):954-960. PMID: 24997607; PMCID: PMC4830134.
    49. Gourraud PA, Khankhanian P, Cereb N, Yang SY, Feolo M, Maiers M, Rioux JD, Hauser S, Oksenberg J. HLA diversity in the 1000 genomes dataset. PLoS One. 2014; 9(7):e97282. PMID: 24988075; PMCID: PMC4079705.
    50. Llufriu S, Kornak J, Ratiney H, Oh J, Brenneman D, Cree BA, Sampat M, Hauser SL, Nelson SJ, Pelletier D. Magnetic resonance spectroscopy markers of disease progression in multiple sclerosis. JAMA Neurol. 2014 Jul 01; 71(7):840-7. PMID: 24839987.
      View in: PubMed
    51. Palanichamy A, Jahn S, Nickles D, Derstine M, Abounasr A, Hauser SL, Baranzini SE, Leppert D, von Büdingen HC. Rituximab efficiently depletes increased CD20-expressing T cells in multiple sclerosis patients. J Immunol. 2014 Jul 15; 193(2):580-586. PMID: 24928997; PMCID: PMC4082756.
    52. Hauser SL. What ethics integration looks like in neuroscience research. Ann Neurol. 2014 May; 75(5):623-4. PMID: 24801670.
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    53. Bankoti J, Apeltsin L, Hauser SL, Allen S, Albertolle ME, Witkowska HE, von Büdingen HC. In multiple sclerosis, oligoclonal bands connect to peripheral B-cell responses. Ann Neurol. 2014 Feb; 75(2):266-76. PMID: 24375699; PMCID: PMC3961546.
    54. Hauser SL, Johnston SC, Ferriero DM, Josephson SA, Lowenstein DH, Messing RO, Oksenberg JR. Quo vadis? Peering into the future. Ann Neurol. 2013 Dec; 74(6):A5-7. PMID: 24448838.
      View in: PubMed
    55. Johnston SC, Ferriero DM, Josephson SA, Lowenstein DH, Messing RO, Oksenberg J, Stewart A, Hauser SL. Have the Annals editors added value? Ann Neurol. 2013 Nov; 74(5):A7-9. PMID: 24353220.
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    56. Harbo HF, Isobe N, Berg-Hansen P, Bos SD, Caillier SJ, Gustavsen MW, Mero IL, Celius EG, Hauser SL, Oksenberg JR, Gourraud PA. Oligoclonal bands and age at onset correlate with genetic risk score in multiple sclerosis. Mult Scler. 2014 May; 20(6):660-8. PMID: 24099750; PMCID: PMC4066985.
    57. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet. 2013 Nov; 45(11):1353-60. PMID: 24076602.
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    58. Josephson SA, Johnston SC, Hauser SL. Blockbusters for cheap? The difficulties surrounding generic biologics. Ann Neurol. 2013 Sep; 74(3):A7-8. PMID: 24115256.
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    59. Brown RH, Hauser SL. Introduction to a special edition of Annals: Therapeutic prospects. Ann Neurol. 2013 Sep; 74(3):A15. PMID: 24115255.
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    60. Hauser SL, Chan JR, Oksenberg JR. Multiple sclerosis: Prospects and promise. Ann Neurol. 2013 Sep; 74(3):317-27. PMID: 23955638.
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    61. Hauser SL, Johnston SC. Neurology: violence at home. Ann Neurol. 2013 Aug; 74(2):A5-6. PMID: 24902528.
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    62. Hauser SL, Johnston SC. Living in the time of sequestration. Ann Neurol. 2013 Jul; 74(1):A5-6. PMID: 24038125.
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    63. Schulze-Topphoff U, Casazza S, Varrin-Doyer M, Pekarek K, Sobel RA, Hauser SL, Oksenberg JR, Zamvil SS, Baranzini SE. Tob1 plays a critical role in the activation of encephalitogenic T cells in CNS autoimmunity. J Exp Med. 2013 Jul 01; 210(7):1301-9. PMID: 23797093; PMCID: PMC3698524.
    64. Isobe N, Gourraud PA, Harbo HF, Caillier SJ, Santaniello A, Khankhanian P, Maiers M, Spellman S, Cereb N, Yang S, Pando MJ, Piccio L, Cross AH, De Jager PL, Cree BA, Hauser SL, Oksenberg JR. Genetic risk variants in African Americans with multiple sclerosis. Neurology. 2013 Jul 16; 81(3):219-27. PMID: 23771490; PMCID: PMC3770164.
    65. Nickles D, Chen HP, Li MM, Khankhanian P, Madireddy L, Caillier SJ, Santaniello A, Cree BA, Pelletier D, Hauser SL, Oksenberg JR, Baranzini SE. Blood RNA profiling in a large cohort of multiple sclerosis patients and healthy controls. Hum Mol Genet. 2013 Oct 15; 22(20):4194-205. PMID: 23748426; PMCID: PMC3781642.
    66. Johnston SC, Hauser SL. The dangers of clinical conviction: an "M&M" of endovascular therapies for stroke. Ann Neurol. 2013 Jun; 73(6):A5-6. PMID: 23868363.
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    67. Josephson SA, Johnston SC, Hauser SL. The neurologic revolving door: time to pay attention to readmissions. Ann Neurol. 2013 May; 73(5):A5-6. PMID: 23749743.
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    68. Hauser SL, Johnston SC. Big neuroscience. Ann Neurol. 2013 Apr; 73(4):A5-6. PMID: 24643981.
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    72. Johnston SC, Josephson SA, Hauser SL. Are relative value units hurting healthcare? Ann Neurol. 2013 Feb; 73(2):A5-6. PMID: 23526560.
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    73. Hauser SL, Johnston SC. DSM-V: psychodrama on the public stage. Ann Neurol. 2013 Jan; 73(1):A5-6. PMID: 23378334.
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    76. von Büdingen HC, Kuo TC, Sirota M, van Belle CJ, Apeltsin L, Glanville J, Cree BA, Gourraud PA, Schwartzburg A, Huerta G, Telman D, Sundar PD, Casey T, Cox DR, Hauser SL. B cell exchange across the blood-brain barrier in multiple sclerosis. J Clin Invest. 2012 Dec; 122(12):4533-43. PMID: 23160197; PMCID: PMC3533544.
    77. Hauser SL, Josephson SA, Johnston SC. Deciphering the signature injury. Ann Neurol. 2012 Nov; 72(5):A5-6. PMID: 23280802.
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    78. Morris DL, Taylor KE, Fernando MM, Nititham J, Alarcón-Riquelme ME, Barcellos LF, Behrens TW, Cotsapas C, Gaffney PM, Graham RR, Pons-Estel BA, Gregersen PK, Harley JB, Hauser SL, Hom G. Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans. Am J Hum Genet. 2012 Nov 02; 91(5):778-93. PMID: 23084292; PMCID: PMC3487133.
    79. Johnston SC, Hauser SL. Healthcare costs: Eden's apple? Ann Neurol. 2012 Oct; 72(4):A4-5. PMID: 23109164.
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    80. Nickles D, Madireddy L, Yang S, Khankhanian P, Lincoln S, Hauser SL, Oksenberg JR, Baranzini SE. In depth comparison of an individual's DNA and its lymphoblastoid cell line using whole genome sequencing. BMC Genomics. 2012 Sep 14; 13:477. PMID: 22974163; PMCID: PMC3473256.
    81. Hauser SL. Beaten into action: a perspective on blood sports. Ann Neurol. 2012 Sep; 72(3):A4-5. PMID: 23034920.
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    82. Mowry EM, Waubant E, McCulloch CE, Okuda DT, Evangelista AA, Lincoln RR, Gourraud PA, Brenneman D, Owen MC, Qualley P, Bucci M, Hauser SL, Pelletier D. Vitamin D status predicts new brain magnetic resonance imaging activity in multiple sclerosis. Ann Neurol. 2012 Aug; 72(2):234-40. PMID: 22926855; PMCID: PMC3430977.
    83. Hauser SL. Note to aspiring clinician scientists: skies are clearing. Ann Neurol. 2012 Aug; 72(2):A5-6. PMID: 22926869.
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    86. Hauser SL, Johnston SC. Multiple sclerosis drugs: sticker shock. Ann Neurol. 2012 May; 71(5):A5-6. PMID: 22522488.
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    87. Hedges DJ, Hamilton-Nelson KL, Sacharow SJ, Nations L, Beecham GW, Kozhekbaeva ZM, Butler BL, Cukier HN, Whitehead PL, Ma D, Jaworski JM, Nathanson L, Lee JM, Hauser SL, Oksenberg JR, Cuccaro ML, Haines JL, Gilbert JR, Pericak-Vance MA. Evidence of novel fine-scale structural variation at autism spectrum disorder candidate loci. Mol Autism. 2012 Apr 02; 3:2. PMID: 22472195; PMCID: PMC3352055.
    88. Johnston SC, Hauser SL. The neurological exam: striking a nerve. Ann Neurol. 2012 Mar; 71(3):A5. PMID: 22451213.
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    89. Johnston SC, Hauser SL. Modern care for neurological problems must address waste. Ann Neurol. 2012 Feb; 71(2):A5-6. PMID: 22368006.
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    90. Villoslada P, Cuneo A, Gelfand J, Hauser SL, Green A. Color vision is strongly associated with retinal thinning in multiple sclerosis. Mult Scler. 2012 Jul; 18(7):991-9. PMID: 22291035.
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    92. Oksenberg JR, Hauser SL. Decoding multiple sclerosis. Ann Neurol. 2011 Dec; 70(6):A5-7. PMID: 22190375.
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    93. Patsopoulos NA. Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol. 2011 Dec; 70(6):897-912. PMID: 22190364; PMCID: PMC3247076.
    94. Glanville J, Kuo TC, von Büdingen HC, Guey L, Berka J, Sundar PD, Huerta G, Mehta GR, Oksenberg JR, Hauser SL, Cox DR, Rajpal A, Pons J. Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation. Proc Natl Acad Sci U S A. 2011 Dec 13; 108(50):20066-71. PMID: 22123975; PMCID: PMC3250199.
    95. Hauser SL, Johnston SC. Benefits of medical research: Hollywood weighs in. Ann Neurol. 2011 Nov; 70(5):A5-6. PMID: 22162068.
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    96. Kappos L, Li D, Calabresi PA, O'Connor P, Bar-Or A, Barkhof F, Yin M, Leppert D, Glanzman R, Tinbergen J, Hauser SL. Ocrelizumab in relapsing-remitting multiple sclerosis: a phase 2, randomised, placebo-controlled, multicentre trial. Lancet. 2011 Nov 19; 378(9805):1779-87. PMID: 22047971.
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    97. Hauser SL, Johnston SC. Global clinical trials: challenges ahead. Ann Neurol. 2011 Oct; 70(4):A8-9. PMID: 22028240.
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    98. Curran WJ, Paulus R, Langer CJ, Komaki R, Lee JS, Hauser S, Movsas B, Wasserman T, Rosenthal SA, Gore E, Machtay M, Sause W, Cox JD. Sequential vs. concurrent chemoradiation for stage III non-small cell lung cancer: randomized phase III trial RTOG 9410. J Natl Cancer Inst. 2011 Oct 05; 103(19):1452-60. PMID: 21903745; PMCID: PMC3186782.
    99. Hauser SL, Johnston SC. Waking up to narcolepsy. Ann Neurol. 2011 Sep; 70(3):A5-6. PMID: 21866561.
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    100. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature. 2011 Aug 10; 476(7359):214-9. PMID: 21833088.
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    102. Johnston SC, Hauser SL. The beautiful and ethereal neurological exam: an appeal for research. Ann Neurol. 2011 Aug; 70(2):A9-A10. PMID: 21823150.
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    103. Zuvich RL, Bush WS, McCauley JL, Beecham AH, De Jager PL. Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA-CLEC16A-SOCS1 gene complex. Hum Mol Genet. 2011 Sep 01; 20(17):3517-24. PMID: 21653641; PMCID: PMC3153306.
    104. Gelfand JM, Cree BA, McElroy J, Oksenberg J, Green R, Mowry EM, Miller JW, Hauser SL, Green AJ. Vitamin D in African Americans with multiple sclerosis. Neurology. 2011 May 24; 76(21):1824-30. PMID: 21606454; PMCID: PMC3100123.
    105. Roosendaal SD, Bendfeldt K, Vrenken H, Polman CH, Borgwardt S, Radue EW, Kappos L, Pelletier D, Hauser SL, Matthews PM, Barkhof F, Geurts JJ. Grey matter volume in a large cohort of MS patients: relation to MRI parameters and disability. Mult Scler. 2011 Sep; 17(9):1098-106. PMID: 21586487.
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    106. Johnston SC, Hauser SL. The NIH shuffle, NCATS, and neurology. Ann Neurol. 2011 May; 69(5):A9-10. PMID: 21520237.
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    107. Johnston SC, Hauser SL, Desmond-Hellmann S. Enhancing ties between academia and industry to improve health. Nat Med. 2011 Apr; 17(4):434-6. PMID: 21475239.
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    108. Hauser SL, Johnston SC. Extraordinary claims require extraordinary evidence. Ann Neurol. 2011 Apr; 69(4):A9-A10. PMID: 21520226.
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    109. Hauser SL, Johnston SC. Scientific literacy and the media. Ann Neurol. 2011 Mar; 69(3):A9-10. PMID: 21446018.
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    110. Bush WS, McCauley JL, DeJager PL, Dudek SM, Hafler DA, Gibson RA, Matthews PM, Kappos L, Naegelin Y, Polman CH, Hauser SL, Oksenberg J, Haines JL, Ritchie MD. A knowledge-driven interaction analysis reveals potential neurodegenerative mechanism of multiple sclerosis susceptibility. Genes Immun. 2011 Jul; 12(5):335-40. PMID: 21346779; PMCID: PMC3136581.
    111. Wang JH, Pappas D, De Jager PL, Pelletier D, de Bakker PI, Kappos L, Polman CH. Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data. Genome Med. 2011 Jan 18; 3(1):3. PMID: 21244703; PMCID: PMC3092088.
    112. Gourraud PA, McElroy JP, Caillier SJ, Johnson BA, Santaniello A, Hauser SL, Oksenberg JR. Aggregation of multiple sclerosis genetic risk variants in multiple and single case families. Ann Neurol. 2011 Jan; 69(1):65-74. PMID: 21280076; PMCID: PMC3511846.
    113. Josephson SA, Hauser SL. Neurologic education 2011: new challenges and opportunities. Ann Neurol. 2010 Dec; 68(6):A9-10. PMID: 21194145.
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    114. Khankhanian P, Gourraud PA, Caillier SJ, Santaniello A, Hauser SL, Baranzini SE, Oksenberg JR. Genetic variation in the odorant receptors family 13 and the mhc loci influence mate selection in a multiple sclerosis dataset. BMC Genomics. 2010 Nov 10; 11:626. PMID: 21067613; PMCID: PMC3091764.
    115. Josephson SA, Hauser SL, Johnston SC. Malignant middle cerebral artery stroke: Where ischemia meets the scalpel. Ann Neurol. 2010 Oct; 68(4):A6-8. PMID: 20976760.
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    116. Baranzini SE, Srinivasan R, Khankhanian P, Okuda DT, Nelson SJ, Matthews PM, Hauser SL, Oksenberg JR, Pelletier D. Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis. Brain. 2010 Sep; 133(9):2603-11. PMID: 20802204; PMCID: PMC2929334.
    117. Hauser SL, Johnston SC. Fred Plum (1924-2010) and the founding of the Annals of Neurology. Ann Neurol. 2010 Sep; 68(3):A5-7. PMID: 20818781.
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    118. Briggs FB, Bartlett SE, Goldstein BA, Wang J, McCauley JL, Zuvich RL, De Jager PL, Rioux JD, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Oksenberg JR, Sawcer SJ, Pericak-Vance MA, Haines JL. Evidence for CRHR1 in multiple sclerosis using supervised machine learning and meta-analysis in 12,566 individuals. Hum Mol Genet. 2010 Nov 01; 19(21):4286-95. PMID: 20699326; PMCID: PMC2951862.
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    120. Hauser SL, Johnston SC. 4-aminopyridine: new life for an old drug. Ann Neurol. 2010 Jul; 68(1):A8-9. PMID: 20583227.
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    121. Cree BA, Rioux JD, McCauley JL, Gourraud PA, Goyette P, McElroy J, De Jager P, Santaniello A, Vyse TJ, Gregersen PK, Mirel D, Hafler DA, Haines JL, Pericak-Vance MA, Compston A, Sawcer SJ, Oksenberg JR, Hauser SL. A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01. PLoS One. 2010 Jun 25; 5(6):e11296. PMID: 20593013.
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    122. Ban M, McCauley JL, Zuvich R, Baker A, Bergamaschi L, Cox M, Kemppinen A, D'Alfonso S, Guerini FR, Lechner-Scott J, Dudbridge F, Wason J, Robertson NP, De Jager PL, Hafler DA, Barcellos LF, Ivinson AJ, Sexton D, Oksenberg JR, Hauser SL, Pericak-Vance MA, Haines J, Compston A, Sawcer S. A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis. Genes Immun. 2010 Dec; 11(8):660-4. PMID: 20574445; PMCID: PMC2946966.
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    127. Ferriero DM, Hauser SL. Supply does not satisfy demand in child neurology. Ann Neurol. 2010 May; 67(5):A5-6. PMID: 20437550.
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    128. Baranzini SE, Mudge J, van Velkinburgh JC, Khankhanian P, Khrebtukova I, Miller NA, Zhang L, Farmer AD, Bell CJ, Kim RW, May GD, Woodward JE, Caillier SJ, McElroy JP, Gomez R, Pando MJ, Clendenen LE, Ganusova EE, Schilkey FD, Ramaraj T, Khan OA, Huntley JJ, Luo S, Kwok PY, Wu TD, Schroth GP, Oksenberg JR, Hauser SL, Kingsmore SF. Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis. Nature. 2010 Apr 29; 464(7293):1351-6. PMID: 20428171; PMCID: PMC2862593.
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    131. Hauser SL, Johnston SC, Stewart AF. Neuroreconciliation and the health care debate. Ann Neurol. 2010 Apr; 67(4):A5-8. PMID: 20437573.
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    135. Zuvich RL, McCauley JL, Oksenberg JR, Sawcer SJ, De Jager PL. Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility. Hum Genet. 2010 Mar; 127(5):525-35. PMID: 20112030.
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    137. Bryc K, Auton A, Nelson MR, Oksenberg JR, Hauser SL, Williams S, Froment A, Bodo JM, Wambebe C, Tishkoff SA, Bustamante CD. Genome-wide patterns of population structure and admixture in West Africans and African Americans. Proc Natl Acad Sci U S A. 2010 Jan 12; 107(2):786-91. PMID: 20080753; PMCID: PMC2818934.
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    139. Johnston SC, Hauser SL. IOM task impossible: set the agenda for neurological comparative effectiveness research. Ann Neurol. 2009 Nov; 66(5):A4-6. PMID: 19938063.
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    141. Hawker K, O'Connor P, Freedman MS, Calabresi PA, Antel J, Simon J, Hauser S, Waubant E, Vollmer T, Panitch H, Zhang J, Chin P, Smith CH. Rituximab in patients with primary progressive multiple sclerosis: results of a randomized double-blind placebo-controlled multicenter trial. Ann Neurol. 2009 Oct; 66(4):460-71. PMID: 19847908.
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    142. Hauser SL, Johnston SC. Balancing risk and reward: the question of natalizumab. Ann Neurol. 2009 Sep; 66(3):A7-8. PMID: 19810091.
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    143. Johnston SC, Hauser SL. Disparities in care: guilty until proven innocent. Ann Neurol. 2009 Aug; 66(2):A7-8. PMID: 19743464.
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    144. Hauser SL, Johnston SC. Journeys in complex genetics: music and mental illness. Ann Neurol. 2009 Jul; 66(1):A7-9. PMID: 19681105.
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    145. De Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, Aggarwal NT, Piccio L, Raychaudhuri S, Tran D, Aubin C, Briskin R, Romano S. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet. 2009 Jul; 41(7):776-82. PMID: 19525953; PMCID: PMC2757648.
    146. Johnston SC, Hauser SL. Crowdsourcing scientific innovation. Ann Neurol. 2009 Jun; 65(6):A7-8. PMID: 19562693.
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    147. Hauser SL, Stewart AF, Johnston SC. Message from the editor: on humility. Ann Neurol. 2009 May; 65(5):A7-8. PMID: 19479725.
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    148. Johnston SC, Hauser SL. Economic over-stimulation? Ann Neurol. 2009 Apr; 65(4):A7-8. PMID: 19399856.
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    149. Ban M, Goris A, Lorentzen AR, Baker A, Mihalova T, Ingram G, Booth DR, Heard RN, Stewart GJ, Bogaert E, Dubois B, Harbo HF, Celius EG, Spurkland A, Strange R, Hawkins C, Robertson NP, Dudbridge F, Wason J, De Jager PL, Hafler D, Rioux JD, Ivinson AJ, McCauley JL, Pericak-Vance M, Oksenberg JR, Hauser SL, Sexton D, Haines J, Sawcer S. Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor. Eur J Hum Genet. 2009 Oct; 17(10):1309-13. PMID: 19293837.
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    150. Baranzini SE, Galwey NW, Wang J, Khankhanian P, Lindberg R, Pelletier D, Wu W, Uitdehaag BM, Kappos L. Pathway and network-based analysis of genome-wide association studies in multiple sclerosis. Hum Mol Genet. 2009 Jun 01; 18(11):2078-90. PMID: 19286671; PMCID: PMC2678928.
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    152. De Jager PL, Baecher-Allan C, Maier LM, Arthur AT, Ottoboni L, Barcellos L, McCauley JL, Sawcer S, Goris A, Saarela J, Yelensky R, Price A, Leppa V, Patterson N, de Bakker PI, Tran D, Aubin C, Pobywajlo S, Rossin E, Hu X, Ashley CW, Choy E, Rioux JD, Pericak-Vance MA, Ivinson A, Booth DR, Stewart GJ, Palotie A, Peltonen L, Dubois B, Haines JL, Weiner HL, Compston A, Hauser SL, Daly MJ, Reich D, Oksenberg JR, Hafler DA. The role of the CD58 locus in multiple sclerosis. Proc Natl Acad Sci U S A. 2009 Mar 31; 106(13):5264-9. PMID: 19237575; PMCID: PMC2664005.
    153. Cree BA, Reich DE, Khan O, De Jager PL, Nakashima I, Takahashi T, Bar-Or A, Tong C, Hauser SL, Oksenberg JR. Modification of Multiple Sclerosis Phenotypes by African Ancestry at HLA. Arch Neurol. 2009 Feb; 66(2):226-33. PMID: 19204159; PMCID: PMC4334456.
    154. Johnston SC, Hauser SL. Comparative effectiveness research in the neurosciences. Ann Neurol. 2009 Feb; 65(2):A6-8. PMID: 19260031.
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    155. Maier LM, Lowe CE, Cooper J, Downes K, Anderson DE, Severson C, Clark PM, Healy B, Walker N, Aubin C, Oksenberg JR, Hauser SL, Compston A, Sawcer S. IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production. PLoS Genet. 2009 Jan; 5(1):e1000322. PMID: 19119414.
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    156. Hauser SL, Johnston SC. Translational research for a new administration: what sort of change to believe in? Ann Neurol. 2008 Dec; 64(6):A5-6. PMID: 19107987.
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    157. Baranzini SE, Wang J, Gibson RA, Galwey N, Naegelin Y, Barkhof F, Radue EW, Lindberg RL, Uitdehaag BM, Johnson MR, Angelakopoulou A, Hall L, Richardson JC, Prinjha RK, Gass A, Geurts JJ, Kragt J, Sombekke M, Vrenken H, Qualley P, Lincoln RR, Gomez R, Caillier SJ, George MF, Mousavi H, Guerrero R, Okuda DT, Cree BA, Green AJ, Waubant E, Goodin DS, Pelletier D, Matthews PM, Hauser SL, Kappos L, Polman CH, Oksenberg JR. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Hum Mol Genet. 2009 Feb 15; 18(4):767-78. PMID: 19010793; PMCID: PMC4334814.
    158. Johnston SC, Hauser SL. Peer review at National Institutes of Health: small steps forward. Ann Neurol. 2008 Nov; 64(5):A15-7. PMID: 19067350.
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    159. Hauser SL. Multiple lessons for multiple sclerosis. N Engl J Med. 2008 Oct 23; 359(17):1838-41. PMID: 18946071.
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    160. Caillier SJ, Briggs F, Cree BA, Baranzini SE, Fernandez-Viña M, Ramsay PP, Khan O, Royal W, Hauser SL, Barcellos LF, Oksenberg JR. Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis. J Immunol. 2008 Oct 15; 181(8):5473-80. PMID: 18832704; PMCID: PMC4346327.
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    162. Johnston SC, Hauser SL. Investigator balkanization. Ann Neurol. 2008 Sep; 64(3):A11-2. PMID: 18825670.
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    166. Johnston SC, Hauser SL. Neurological disease on the global agenda. Ann Neurol. 2008 Jul; 64(1):A11-2. PMID: 18668532.
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    167. Oksenberg JR, Baranzini SE, Sawcer S, Hauser SL. The genetics of multiple sclerosis: SNPs to pathways to pathogenesis. Nat Rev Genet. 2008 Jul; 9(7):516-26. PMID: 18542080.
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    170. Hauser SL, Johnston SC. Electronic medical records: does it take a village or a thousand points of light? Ann Neurol. 2008 Apr; 63(4):A13-4. PMID: 18438949.
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    171. Claiborne Johnston S, Hauser SL. T2 clinical research: judgment day. Ann Neurol. 2008 Mar; 63(3):A15-6. PMID: 18383074.
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    172. Hauser SL, Waubant E, Arnold DL, Vollmer T, Antel J, Fox RJ, Bar-Or A, Panzara M, Sarkar N, Agarwal S, Langer-Gould A, Smith CH. B-cell depletion with rituximab in relapsing-remitting multiple sclerosis. N Engl J Med. 2008 Feb 14; 358(7):676-88. PMID: 18272891.
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    173. Oksenberg JR, Hauser SL. Neurogenetics in the Annals: dealing with complexity. Ann Neurol. 2008 Feb; 63(2):A11-4. PMID: 18306395.
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    174. Johnston SC, Hauser SL. Clinical trials: rising costs limit innovation. Ann Neurol. 2007 Dec; 62(6):A6-7. PMID: 18161783.
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    175. Begovich AB, Chang M, Caillier SJ, Lew D, Catanese JJ, Wang J, Hauser SL, Oksenberg JR. The autoimmune disease-associated IL12B and IL23R polymorphisms in multiple sclerosis. Hum Immunol. 2007 Nov; 68(11):934-7. PMID: 18082575.
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    176. Hauser SL, Johnston SC. The upcoming meeting of the ANA. Ann Neurol. 2007 Sep; 62(3):A11. PMID: 17894364.
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    177. McCauley JL, Kenealy SJ, Margulies EH, Schnetz-Boutaud N, Gregory SG, Hauser SL, Oksenberg JR, Pericak-Vance MA, Haines JL, Mortlock DP. SNPs in Multi-species Conserved Sequences (MCS) as useful markers in association studies: a practical approach. BMC Genomics. 2007 Aug 06; 8:266. PMID: 17683615; PMCID: PMC1959193.
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    179. Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med. 2007 Aug 30; 357(9):851-62. PMID: 17660530.
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    180. Hauser SL, Johnston SC. Matriculating the next generation of clinician-scientists. Ann Neurol. 2007 Jul; 62(1):A10-1. PMID: 17657814.
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    181. Kappos L, Bates D, Hartung HP, Havrdova E, Miller D, Polman CH, Ravnborg M, Hauser SL, Rudick RA, Weiner HL, O'Connor PW, King J, Radue EW, Yousry T, Major EO, Clifford DB. Natalizumab treatment for multiple sclerosis: recommendations for patient selection and monitoring. Lancet Neurol. 2007 May; 6(5):431-41. PMID: 17434098.
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    182. Hauser SL, Johnston SC. Medical prizes: Lifetime achievement awards or engines for progress? Ann Neurol. 2007 May; 61(5):A11-2. PMID: 17469123.
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    183. Johnston SC, Lowenstein DH, Ferriero DM, Messing RO, Oksenberg JR, Hauser SL. Early editorial manuscript screening versus obligate peer review: a randomized trial. Ann Neurol. 2007 Apr; 61(4):A10-2. PMID: 17444512.
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    184. Hauser SL, Johnston SC. Of ghosts and sirens: the subtlest lures of industry. Ann Neurol. 2007 Mar; 61(3):A11-2. PMID: 17387728.
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    185. Yeo TW, De Jager PL, Gregory SG, Barcellos LF, Walton A, Goris A, Fenoglio C, Ban M, Taylor CJ, Goodman RS, Walsh E, Wolfish CS, Horton R, Traherne J, Beck S, Trowsdale J, Caillier SJ, Ivinson AJ, Green T, Pobywajlo S, Lander ES, Pericak-Vance MA, Haines JL, Daly MJ, Oksenberg JR, Hauser SL, Compston A, Hafler DA, Rioux JD, Sawcer S. A second major histocompatibility complex susceptibility locus for multiple sclerosis. Ann Neurol. 2007 Mar; 61(3):228-36. PMID: 17252545; PMCID: PMC2737610.
    186. Johnston SC, Hauser SL. Marketing and drug costs: who is laughing and crying? Ann Neurol. 2007 Feb; 61(2):11A-12A. PMID: 17315204.
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    187. Johnston SC, Hauser SL. A status report on neuroscience research, without grade inflation. Ann Neurol. 2006 Dec; 60(6):A9-11. PMID: 17192939.
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    188. Hauser SL, Johnston SC. Recombinant therapeutics: from bench to bedside (if your health plan concurs). Ann Neurol. 2006 Nov; 60(5):10A-11A. PMID: 17120255.
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    189. Barcellos LF, Kamdar BB, Ramsay PP, DeLoa C, Lincoln RR, Caillier S, Schmidt S, Haines JL, Pericak-Vance MA, Oksenberg JR, Hauser SL. Clustering of autoimmune diseases in families with a high-risk for multiple sclerosis: a descriptive study. Lancet Neurol. 2006 Nov; 5(11):924-31. PMID: 17052659.
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    190. Hauser SL, Oksenberg JR. The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration. Neuron. 2006 Oct 05; 52(1):61-76. PMID: 17015227.
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    191. Johnston SC, Hauser SL. Neurology and medical devices. Ann Neurol. 2006 Oct; 60(4):11A-2A. PMID: 17068793.
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    192. Motsinger AA, Brassat D, Caillier SJ, Erlich HA, Walker K, Steiner LL, Barcellos LF, Pericak-Vance MA, Schmidt S, Gregory S, Hauser SL, Haines JL, Oksenberg JR, Ritchie MD. Complex gene-gene interactions in multiple sclerosis: a multifactorial approach reveals associations with inflammatory genes. Neurogenetics. 2007 Jan; 8(1):11-20. PMID: 17024427.
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    193. Hauser SL, McArthur JC. Saving the clinician-scientist: report of the ANA long range planning committee. Ann Neurol. 2006 Sep; 60(3):278-85. PMID: 16983684.
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    194. Barcellos LF, Sawcer S, Ramsay PP, Baranzini SE, Thomson G, Briggs F, Cree BC, Begovich AB, Villoslada P, Montalban X, Uccelli A, Savettieri G, Lincoln RR, DeLoa C, Haines JL, Pericak-Vance MA, Compston A, Hauser SL, Oksenberg JR. Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis. Hum Mol Genet. 2006 Sep 15; 15(18):2813-24. PMID: 16905561.
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    195. Johnston SC, Hauser SL. Basic and clinical research: what is the most appropriate weighting in a public investment portfolio? Ann Neurol. 2006 Jul; 60(1):9A-11A. PMID: 16802300.
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    196. Hauser SL. Sleepiness in the elderly. Ann Neurol. 2006 Jun; 59(6):9A-10A. PMID: 16718697.
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    197. Hauser SL. Low-grade central nervous system lymphoma: clarity through a hazy lens. Ann Neurol. 2006 May; 59(5):9A-10A. PMID: 16634011.
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    198. Hauser SL, Weiner HL. Natalizumab: immune effects and implications for therapy. Ann Neurol. 2006 May; 59(5):731-2. PMID: 16634007.
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    199. Hauser SL. Multiple sclerosis: tip of the iceberg? Ann Neurol. 2006 Apr; 59(4):11A-12A. PMID: 16566010.
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    200. von Büdingen HC, Menge T, Hauser SL, Genain CP. Restrictive and diversifying elements of the anti-myelin/oligodendrocyte glycoprotein antibody response in primate experimental allergic encephalomyelitis. Immunogenetics. 2006 Apr; 58(2-3):122-8. PMID: 16528499.
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    201. Traherne JA, Barcellos LF, Sawcer SJ, Compston A, Ramsay PP, Hauser SL, Oksenberg JR, Trowsdale J. Association of the truncating splice site mutation in BTNL2 with multiple sclerosis is secondary to HLA-DRB1*15. Hum Mol Genet. 2006 Jan 01; 15(1):155-61. PMID: 16321988.
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    202. Frohman EM, Stüve O, Havrdova E, Corboy J, Achiron A, Zivadinov R, Sorensen PS, Phillips JT, Weinshenker B, Hawker K, Hartung HP, Steinman L, Zamvil S, Cree BA, Hauser S, Weiner H, Racke MK, Filippi M. Therapeutic considerations for disease progression in multiple sclerosis: evidence, experience, and future expectations. Arch Neurol. 2005 Oct; 62(10):1519-30. PMID: 16216934.
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    203. Fernald GH, Yeh RF, Hauser SL, Oksenberg JR, Baranzini SE. Mapping gene activity in complex disorders: Integration of expression and genomic scans for multiple sclerosis. J Neuroimmunol. 2005 Oct; 167(1-2):157-69. PMID: 16129498.
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    204. Reich D, Patterson N, De Jager PL, McDonald GJ, Waliszewska A, Tandon A, Lincoln RR, DeLoa C, Fruhan SA, Cabre P, Bera O, Semana G, Kelly MA, Francis DA, Ardlie K, Khan O, Cree BA, Hauser SL, Oksenberg JR, Hafler DA. A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility. Nat Genet. 2005 Oct; 37(10):1113-8. PMID: 16186815.
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    205. Menge T, Lalive PH, von Büdingen HC, Cree B, Hauser SL, Genain CP. Antibody responses against galactocerebroside are potential stage-specific biomarkers in multiple sclerosis. J Allergy Clin Immunol. 2005 Aug; 116(2):453-9. PMID: 16083805.
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    206. Sawcer S, Ban M, Maranian M, Yeo TW, Compston A, Kirby A, Daly MJ, De Jager PL, Walsh E, Lander ES, Rioux JD, Hafler DA, Ivinson A, Rimmler J, Gregory SG, Schmidt S, Pericak-Vance MA, Akesson E, Hillert J, Datta P, Oturai A, Ryder LP, Harbo HF, Spurkland A, Myhr KM, Laaksonen M, Booth D, Heard R, Stewart G, Lincoln R, Barcellos LF, Hauser SL, Oksenberg JR, Kenealy SJ, Haines JL. A high-density screen for linkage in multiple sclerosis. Am J Hum Genet. 2005 Sep; 77(3):454-67. PMID: 16080120; PMCID: PMC1226210.
    207. Oksenberg JR, Hauser SL. Genetics of multiple sclerosis. Neurol Clin. 2005 Feb; 23(1):61-75, vi. PMID: 15661088.
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    208. Begovich AB, Caillier SJ, Alexander HC, Penko JM, Hauser SL, Barcellos LF, Oksenberg JR. The R620W polymorphism of the protein tyrosine phosphatase PTPN22 is not associated with multiple sclerosis. Am J Hum Genet. 2005 Jan; 76(1):184-7. PMID: 15580548; PMCID: PMC1196423.
    209. Hauser SL. An update on multiple sclerosis. J Neurol Sci. 2005 Feb 15; 228(2):193-4. PMID: 15694203.
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    210. Hauser SL. The shape of things to come. Neurology. 2004 Sep 28; 63(6):948-50. PMID: 15452280.
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    211. von Büdingen HC, Hauser SL, Ouallet JC, Tanuma N, Menge T, Genain CP. Frontline: Epitope recognition on the myelin/oligodendrocyte glycoprotein differentially influences disease phenotype and antibody effector functions in autoimmune demyelination. Eur J Immunol. 2004 Aug; 34(8):2072-83. PMID: 15259004.
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    212. Oksenberg JR, Hauser SL. Re: GAMES issue. J Neuroimmunol. 2004 Aug; 153(1-2):1-2. PMID: 15338519.
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    213. Sawcer SJ, Maranian M, Singlehurst S, Yeo T, Compston A, Daly MJ, De Jager PL, Gabriel S, Hafler DA, Ivinson AJ, Lander ES, Rioux JD, Walsh E, Gregory SG, Schmidt S, Pericak-Vance MA, Barcellos L, Hauser SL, Oksenberg JR, Kenealy SJ, Haines JL. Enhancing linkage analysis of complex disorders: an evaluation of high-density genotyping. Hum Mol Genet. 2004 Sep 01; 13(17):1943-9. PMID: 15238506.
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    214. Barcellos LF, Begovich AB, Reynolds RL, Caillier SJ, Brassat D, Schmidt S, Grams SE, Walker K, Steiner LL, Cree BA, Stillman A, Lincoln RR, Pericak-Vance MA, Haines JL, Erlich HA, Hauser SL, Oksenberg JR. Linkage and association with the NOS2A locus on chromosome 17q11 in multiple sclerosis. Ann Neurol. 2004 Jun; 55(6):793-800. PMID: 15174013.
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    215. Patterson N, Hattangadi N, Lane B, Lohmueller KE, Hafler DA, Oksenberg JR, Hauser SL, Smith MW, O'Brien SJ, Altshuler D, Daly MJ, Reich D. Methods for high-density admixture mapping of disease genes. Am J Hum Genet. 2004 May; 74(5):979-1000. PMID: 15088269; PMCID: PMC1181990.
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    217. Pericak-Vance MA, Rimmler JB, Haines JL, Garcia ME, Oksenberg JR, Barcellos LF, Lincoln R, Hauser SL, Cournu-Rebeix I, Azoulay-Cayla A, Lyon-Caen O, Fontaine B, Duhamel E, Coppin H, Brassat D, Roth MP, Clanet M, Alizadeh M, Yaouanq J, Quelvennec E, Semana G, Edan G, Babron MC, Genin E, Clerget-Darpoux F. Investigation of seven proposed regions of linkage in multiple sclerosis: an American and French collaborative study. Neurogenetics. 2004 Feb; 5(1):45-8. PMID: 14595552.
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    218. Rudick RA, Cookfair DL, Griffin J, Hauser S, Piantadosi S. Interferons in relapsing remitting multiple sclerosis. Lancet. 2003 May 24; 361(9371):1824; author reply 1824-5. PMID: 12781561.
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    219. Baranzini SE, Hauser SL. Large-scale gene-expression studies and the challenge of multiple sclerosis. Genome Biol. 2002 Sep 16; 3(10):reviews1027. PMID: 12372148; PMCID: PMC244911.
    220. Haines JL, Bradford Y, Garcia ME, Reed AD, Neumeister E, Pericak-Vance MA, Rimmler JB, Menold MM, Martin ER, Oksenberg JR, Barcellos LF, Lincoln R, Hauser SL. Multiple susceptibility loci for multiple sclerosis. Hum Mol Genet. 2002 Sep 15; 11(19):2251-6. PMID: 12217953.
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    221. Stüve O, Cree BC, von Büdingen HC, Yousef S, Bowen JD, Genain CP, Hauser SL, Steinman L, Zamvil SS. Approved and future pharmacotherapy for multiple sclerosis. Neurologist. 2002 Sep; 8(5):290-301. PMID: 12803676.
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    222. Villoslada P, Barcellos LF, Rio J, Begovich AB, Tintore M, Sastre-Garriga J, Baranzini SE, Casquero P, Hauser SL, Montalban X, Oksenberg JR. The HLA locus and multiple sclerosis in Spain. Role in disease susceptibility, clinical course and response to interferon-beta. J Neuroimmunol. 2002 Sep; 130(1-2):194-201. PMID: 12225902.
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    223. von Büdingen HC, Hauser SL, Fuhrmann A, Nabavi CB, Lee JI, Genain CP. Molecular characterization of antibody specificities against myelin/oligodendrocyte glycoprotein in autoimmune demyelination. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):8207-12. PMID: 12060766; PMCID: PMC123046.
    224. Koehler NK, Genain CP, Giesser B, Hauser SL. The human T cell response to myelin oligodendrocyte glycoprotein: a multiple sclerosis family-based study. J Immunol. 2002 Jun 01; 168(11):5920-7. PMID: 12023398.
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    225. Cree BA, Goodin DS, Hauser SL. Neuromyelitis optica. Semin Neurol. 2002 Jun; 22(2):105-22. PMID: 12524556.
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    226. Baranzini SE, Oksenberg JR, Hauser SL. New insights into the genetics of multiple sclerosis. J Rehabil Res Dev. 2002 Mar-Apr; 39(2):201-9. PMID: 12051464.
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    227. Schmidt S, Barcellos LF, DeSombre K, Rimmler JB, Lincoln RR, Bucher P, Saunders AM, Lai E, Martin ER, Vance JM, Oksenberg JR, Hauser SL, Pericak-Vance MA, Haines JL. Association of polymorphisms in the apolipoprotein E region with susceptibility to and progression of multiple sclerosis. Am J Hum Genet. 2002 Mar; 70(3):708-17. PMID: 11836653; PMCID: PMC384947.