Smita Patel, PhD

Title(s)Staff Research Associate IV, Institute for Neurodegenerative Diseases
SchoolSchool of Medicine
Address675 Nelson Rising Lane
San Francisco CA 94158
PronounsMy name only
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    PhD

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Pol γ possesses separate metal binding sites for polymerase and strand displacement functions. Nucleic Acids Res. 2026 Jul 17; 54(14). Baruch-Torres N, Park J, Mora-Garduño J, Roy A, Singh A, Cisneros GA, Brieba LG, Patel SS, Yin YW. PMID: 42475679; PMCID: PMC13384260.
      View in: PubMed   Mentions:
    2. Human RIG-I Antiviral Deficiency Caused by a Dominant-Negative Variant Locked in a Signaling-Inactive State. medRxiv. 2026 Mar 06. Solotchi M, Jing H, Gebauer E, Novick SJ, Pascal BD, Tung W, Hanpude P, Madura T, Zhang Y, Alba C, Saracino A, Laghetti P, Shaw ER, Rosen LB, Holland SM, Lisco A, Dalgard CL, Marcotrigiano J, Griffin PR, Su HC, Patel SS. PMID: 41822687; PMCID: PMC12976907.
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    3. Human mitochondrial helicase Twinkle has RNA binding, annealing, and strand-exchange activities. Nucleic Acids Res. 2026 Jan 14; 54(2). Singh A, Johnson LC, Baruch-Torres N, Yin YW, Patel SS. PMID: 41562253; PMCID: PMC12820530.
      View in: PubMed   Mentions:
    4. Torsion is a dynamic regulator of DNA replication stalling and reactivation. Nat Commun. 2025 Nov 26; 16(1):10543. Jia X, Gao X, Zhang S, Inman JT, Hong Y, Singh A, Rashid F, Berger JM, Patel SS, Wang MD. PMID: 41298417; PMCID: PMC12658067.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    5. Comparative Rates of Acute Ischemic Stroke Incidence: Native Hawaiians or Pacific Islanders vs Other Races and Ethnic Groups in 4 US States. Neurology. 2025 Sep 23; 105(6):e214105. Otite FO, Morris NA, Anikpezie N, Pitter D, Miller R, Bako AT, Aneni E, Atchaneeyasakul K, Patel SD, Sahoo A, Wee CD, Albright KC, Latorre JGS, Singla A, Khandelwal P, Williams OA, Chaturvedi S, Ovbiagele B. PMID: 40865027.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. DNA Polymerase Locks Replication Fork Under Stress. bioRxiv. 2024 Oct 10. Jia X, Inman JT, Singh A, Patel SS, Wang MD. PMID: 39416053; PMCID: PMC11482901.
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    7. Lee Silverman voice treatment versus NHS speech and language therapy versus control for dysarthria in people with Parkinson's disease (PD COMM): pragmatic, UK based, multicentre, three arm, parallel group, unblinded, randomised controlled trial. BMJ. 2024 07 10; 386:e078341. Sackley CM, Rick C, Brady MC, Woolley R, Burton C, Patel S, Masterson-Algar P, Nicoll A, Smith CH, Jowett S, Ives N, Beaton G, Dickson S, Ottridge R, Sharp L, Nankervis H, Clarke CE, PD COMM collaborative group. PMID: 38986549; PMCID: PMC11232530.
      View in: PubMed   Mentions:
    8. The impact of obstructive sleep apnea treatment on microvascular complications in patients with type 2 diabetes: a feasibility randomized controlled trial. J Clin Sleep Med. 2024 06 01; 20(6):947-957. Makhdom EA, Maher A, Ottridge R, Nicholls M, Ali A, Cooper BG, Ajjan RA, Bellary S, Hanif W, Hanna F, Hughes D, Jayagopal V, Mahto R, Patel M, Young J, Nayak AU, Chen MZ, Kyaw-Tun J, Gonzalez S, Gouni R, Subramanian A, Adderley N, Patel S, Tahrani AA. PMID: 38318821; PMCID: PMC11145053.
      View in: PubMed   Mentions:
    9. Trends in Age, Sex, and Racial Differences in the Incidence of Infective Endocarditis in Florida and New York. Circulation. 2024 Apr 23; 149(17):1391-1393. Anuforo A, Aneni E, Akintoye E, Anikpezie N, Patel SD, Soipe A, Olojakpoke E, Burke D, Latorre JG, Khandelwal P, Chaturvedi S, Ovbiagele B, Otite FO. PMID: 38648273.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    10. The NS1 protein of influenza B virus binds 5'-triphosphorylated dsRNA to suppress RIG-I activation and the host antiviral response. bioRxiv. 2024 Jan 24. Woltz R, Schweibenz B, Tsutakawa SE, Zhao C, Ma L, Shurina B, Hura GL, John R, Vorobiev S, Swapna G, Solotchi M, Tainer JA, Krug RM, Patel SS, Montelione GT. PMID: 38328244; PMCID: PMC10849492.
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    11. Expression and Purification of Recombinant Human Mitochondrial RNA Polymerase (POLRMT) and the Initiation Factors TFAM and TFB2M. Bio Protoc. 2023 Dec 05; 13(23):e4892. Hsieh AH, Reardon SD, Munozvilla-Cabellon JH, Shen J, Patel SS, Mishanina TV. PMID: 38094251; PMCID: PMC10714150.
      View in: PubMed   Mentions: 3  
    12. Antidepressants for the prevention of depression following first-episode psychosis (ADEPP): study protocol for a multi-centre, double-blind, randomised controlled trial. Trials. 2023 Oct 06; 24(1):646. Palmer ER, Griffiths SL, Watkins B, Weetman T, Ottridge R, Patel S, Woolley R, Tearne S, Au P, Taylor E, Sadiq Z, Al-Janabi H, Major B, Marriott C, Husain N, Katshu MZUH, Giacco D, Barnes NM, Walters JTR, Barnes TRE, Birchwood M, Drake R, Upthegrove R. PMID: 37803384; PMCID: PMC10557320.
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    13. Complication Rates Following Cerebral and Coronary Angiography: Nationwide Analysis 2008-2014. Cardiol Rev. 2024 Nov-Dec 01; 32(6):507-512. Lapow JM, Pammal RS, Brozynski M, Sudol S, Patel SD, Feldstein E, Nolan BE, Clare KM, Shapiro S, Kamal H, Amuluru K, Frishman W, Naidu S, Cooper H, Gandhi CD, Al-Mufti F. PMID: 36897085.
      View in: PubMed   Mentions:
    14. Age- and Sex-Specific Trends in Medical Complications After Acute Ischemic Stroke in the United States. Neurology. 2023 03 21; 100(12):e1282-e1295. Ahmed R, Mhina C, Philip K, Patel SD, Aneni E, Osondu C, Lamikanra O, Akano EO, Anikpezie N, Albright KC, Latorre JG, Chaturvedi S, Otite FO. PMID: 36599695; PMCID: PMC10033158.
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    15. Trends in the Incidence of Spontaneous Subarachnoid Hemorrhages in the United States, 2007-2017. Neurology. 2023 01 10; 100(2):e123-e132. Xia C, Hoffman H, Anikpezie N, Philip K, Wee C, Choudhry R, Albright KC, Masoud H, Beutler T, Schmidt E, Gould G, Patel SD, Akano EO, Morris N, Chaturvedi S, Aneni E, Lamikanra O, Chin L, Latorre JG, Otite FO. PMID: 36289004; PMCID: PMC10499430.
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    16. Outcomes among patients with primary angiitis of the CNS: A Nationwide United States analysis. J Stroke Cerebrovasc Dis. 2022 Nov; 31(11):106747. Patel SD, Oliver FO, Elmashad A, Patel N, Mehta T, Hinman J, Liebeskind DS, Singhal AB, Ducros A, Saver JL. PMID: 36162376.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Platelet FcγRIIa Expression in Ischemic Stroke: A Marker of Increased Platelet Reactivity. Stroke Vasc Interv Neurol. 2022 May; 2(3):e000201. Schneider DJ, Honda T, Feldmann E, de Havenon A, Romano JG, Nogueira RG, Prabhakaran S, Mishra NK, Beaman CB, Hinman J, Commichau CS, Callas P, Kaneko N, Morales JM, Patel SD, Sharma LK, Kim SJ, Taatjes-Sommer HS, Liebeskind DS. PMID: 41583630; PMCID: PMC12778771.
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    18. Long-term Effectiveness of Adjuvant Treatment With Catechol-O-Methyltransferase or Monoamine Oxidase B Inhibitors Compared With Dopamine Agonists Among Patients With Parkinson Disease Uncontrolled by Levodopa Therapy: The PD MED Randomized Clinical Trial. JAMA Neurol. 2022 02 01; 79(2):131-140. Gray R, Patel S, Ives N, Rick C, Woolley R, Muzerengi S, Gray A, Jenkinson C, McIntosh E, Wheatley K, Williams A, Clarke CE, PD MED Collaborative Group. PMID: 34962574; PMCID: PMC8715387.
      View in: PubMed   Mentions:
    19. Ischemic Stroke and Pulmonary Arteriovenous Malformations: A Review. Neurology. 2022 02 01; 98(5):188-198. Topiwala KK, Patel SD, Saver JL, Streib CD, Shovlin CL. PMID: 34880092; PMCID: PMC8826462.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    20. Use of core outcome sets was low in clinical trials published in major medical journals. J Clin Epidemiol. 2022 02; 142:19-28. Matvienko-Sikar K, Avery K, Blazeby JM, Devane D, Dodd S, Egan AM, Gorst SL, Hughes K, Jacobsen P, Kirkham JJ, Kottner J, Mellor K, Millward CP, Patel S, Quirke F, Saldanha IJ, Smith V, Terwee CB, Young AE, Williamson PR. PMID: 34715310.
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    21. Excessive excision of correct nucleotides during DNA synthesis explained by replication hurdles. EMBO J. 2020 03 16; 39(6):e103367. Singh A, Pandey M, Nandakumar D, Raney KD, Yin YW, Patel SS. PMID: 32037587; PMCID: PMC7073461.
      View in: PubMed   Mentions:
    22. Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy. PLoS Pathog. 2020 02; 16(2):e1008222. Woerman AL, Patel S, Kazmi SA, Oehler A, Lee J, Mordes DA, Olson SH, Prusiner SB. PMID: 32017806; PMCID: PMC6999861.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    23. Thirty-Day Readmissions After Upper and Lower Gastrointestinal Hemorrhage: A National Perspective in the United States. J Clin Gastroenterol. 2019 09; 53(8):582-590. Patel SD, Desai R, Patel U, Singh S, Patel Z, Patel N, Zhang A, Panwala AH, Khan VN, Singh G, Shah N. PMID: 29561353.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    24. Time-resolved analysis of transcription through chromatin. Methods. 2019 04 15; 159-160:90-95. Chang HW, Hsieh FK, Patel SS, Studitsky VM. PMID: 30707952; PMCID: PMC6589111.
      View in: PubMed   Mentions:
    25. HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity. Nat Commun. 2018 12 18; 9(1):5366. Zheng J, Wang C, Chang MR, Devarkar SC, Schweibenz B, Crynen GC, Garcia-Ordonez RD, Pascal BD, Novick SJ, Patel SS, Marcotrigiano J, Griffin PR. PMID: 30560918; PMCID: PMC6299088.
      View in: PubMed   Mentions:
    26. Highly efficient 5' capping of mitochondrial RNA with NAD+ and NADH by yeast and human mitochondrial RNA polymerase. Elife. 2018 12 12; 7. Bird JG, Basu U, Kuster D, Ramachandran A, Grudzien-Nogalska E, Towheed A, Wallace DC, Kiledjian M, Temiakov D, Patel SS, Ebright RH, Nickels BE. PMID: 30526856; PMCID: PMC6298784.
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    27. Helicase promotes replication re-initiation from an RNA transcript. Nat Commun. 2018 06 13; 9(1):2306. Sun B, Singh A, Sultana S, Inman JT, Patel SS, Wang MD. PMID: 29899338; PMCID: PMC5997990.
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    28. Correlating Transcription Initiation and Conformational Changes by a Single-Subunit RNA Polymerase with Near Base-Pair Resolution. Mol Cell. 2018 05 17; 70(4):695-706.e5. Koh HR, Roy R, Sorokina M, Tang GQ, Nandakumar D, Patel SS, Ha T. PMID: 29775583; PMCID: PMC5983381.
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    29. Familial Parkinson's point mutation abolishes multiple system atrophy prion replication. Proc Natl Acad Sci U S A. 2018 01 09; 115(2):409-414. Woerman AL, Kazmi SA, Patel S, Aoyagi A, Oehler A, Widjaja K, Mordes DA, Olson SH, Prusiner SB. PMID: 29279394; PMCID: PMC5777081.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    30. Kinetics of Human Mutant Tau Prion Formation in the Brains of 2 Transgenic Mouse Lines. JAMA Neurol. 2017 12 01; 74(12):1464-1472. Woerman AL, Patel S, Kazmi SA, Oehler A, Freyman Y, Espiritu L, Cotter R, Castaneda JA, Olson SH, Prusiner SB. PMID: 29059326; PMCID: PMC5822201.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    31. Tau prions from Alzheimer's disease and chronic traumatic encephalopathy patients propagate in cultured cells. Proc Natl Acad Sci U S A. 2016 12 13; 113(50):E8187-E8196. Woerman AL, Aoyagi A, Patel S, Kazmi SA, Lobach I, Grinberg LT, McKee AC, Seeley WW, Olson SH, Prusiner SB. PMID: 27911827; PMCID: PMC5167200.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansCells
    32. DNA looping mediates nucleosome transfer. Nat Commun. 2016 11 03; 7:13337. Brennan LD, Forties RA, Patel SS, Wang MD. PMID: 27808093; PMCID: PMC5097161.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    33. Guinea Pig Prion Protein Supports Rapid Propagation of Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease Prions. J Virol. 2016 11 01; 90(21):9558-9569. Watts JC, Giles K, Saltzberg DJ, Dugger BN, Patel S, Oehler A, Bhardwaj S, Sali A, Prusiner SB. PMID: 27440899; PMCID: PMC5068510.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    34. Clinical effectiveness and cost-effectiveness of physiotherapy and occupational therapy versus no therapy in mild to moderate Parkinson's disease: a large pragmatic randomised controlled trial (PD REHAB). Health Technol Assess. 2016 08; 20(63):1-96. Clarke CE, Patel S, Ives N, Rick CE, Woolley R, Wheatley K, Walker MF, Zhu S, Kandiyali R, Yao G, Sackley CM. PMID: 27580669; PMCID: PMC5018686.
      View in: PubMed   Mentions:
    35. Towards authentic transgenic mouse models of heritable PrP prion diseases. Acta Neuropathol. 2016 10; 132(4):593-610. Watts JC, Giles K, Bourkas ME, Patel S, Oehler A, Gavidia M, Bhardwaj S, Lee J, Prusiner SB. PMID: 27350609; PMCID: PMC5152593.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    36. Physiotherapy and Occupational Therapy vs No Therapy in Mild to Moderate Parkinson Disease: A Randomized Clinical Trial. JAMA Neurol. 2016 Mar; 73(3):291-9. Clarke CE, Patel S, Ives N, Rick CE, Dowling F, Woolley R, Wheatley K, Walker MF, Sackley CM, PD REHAB Collaborative Group. PMID: 26785394.
      View in: PubMed   Mentions:
    37. Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I. Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3):596-601. Devarkar SC, Wang C, Miller MT, Ramanathan A, Jiang F, Khan AG, Patel SS, Marcotrigiano J. PMID: 26733676; PMCID: PMC4725518.
      View in: PubMed   Mentions:
    38. T7 replisome directly overcomes DNA damage. Nat Commun. 2015 Dec 17; 6:10260. Sun B, Pandey M, Inman JT, Yang Y, Kashlev M, Patel SS, Wang MD. PMID: 26675048; PMCID: PMC4703881.
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    39. Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism. Proc Natl Acad Sci U S A. 2015 Sep 22; 112(38):E5308-17. Prusiner SB, Woerman AL, Mordes DA, Watts JC, Rampersaud R, Berry DB, Patel S, Oehler A, Lowe JK, Kravitz SN, Geschwind DH, Glidden DV, Halliday GM, Middleton LT, Gentleman SM, Grinberg LT, Giles K. PMID: 26324905; PMCID: PMC4586853.
      View in: PubMed   Mentions: 425     Fields:    Translation:HumansAnimalsCells
    40. Propagation of prions causing synucleinopathies in cultured cells. Proc Natl Acad Sci U S A. 2015 Sep 01; 112(35):E4949-58. Woerman AL, Stöhr J, Aoyagi A, Rampersaud R, Krejciova Z, Watts JC, Ohyama T, Patel S, Widjaja K, Oehler A, Sanders DW, Diamond MI, Seeley WW, Middleton LT, Gentleman SM, Mordes DA, Südhof TC, Giles K, Prusiner SB. PMID: 26286986; PMCID: PMC4568231.
      View in: PubMed   Mentions: 159     Fields:    Translation:HumansAnimalsCells
    41. Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains. J Pharmacol Exp Ther. 2015 Oct; 355(1):2-12. Giles K, Berry DB, Condello C, Hawley RC, Gallardo-Godoy A, Bryant C, Oehler A, Elepano M, Bhardwaj S, Patel S, Silber BM, Guan S, DeArmond SJ, Renslo AR, Prusiner SB. PMID: 26224882; PMCID: PMC4576665.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    42. Two mechanisms coordinate replication termination by the Escherichia coli Tus-Ter complex. Nucleic Acids Res. 2015 Jul 13; 43(12):5924-35. Pandey M, Elshenawy MM, Jergic S, Takahashi M, Dixon NE, Hamdan SM, Patel SS. PMID: 26007657; PMCID: PMC4499146.
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    43. Finding the right match fast. Cell. 2015 Feb 26; 160(5):809-811. Nandakumar D, Patel SS. PMID: 25723158.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    44. Evidence that bank vole PrP is a universal acceptor for prions. PLoS Pathog. 2014 Apr; 10(4):e1003990. Watts JC, Giles K, Patel S, Oehler A, DeArmond SJ, Prusiner SB. PMID: 24699458; PMCID: PMC3974871.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimals
    45. Relaxed rotational and scrunching changes in P266L mutant of T7 RNA polymerase reduce short abortive RNAs while delaying transition into elongation. PLoS One. 2014; 9(3):e91859. Tang GQ, Nandakumar D, Bandwar RP, Lee KS, Roy R, Ha T, Patel SS. PMID: 24651161; PMCID: PMC3961267.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    46. Single-molecule fluorescence reveals the unwinding stepping mechanism of replicative helicase. Cell Rep. 2014 Mar 27; 6(6):1037-1045. Syed S, Pandey M, Patel SS, Ha T. PMID: 24630993; PMCID: PMC3988844.
      View in: PubMed   Mentions:
    47. Histone chaperone FACT action during transcription through chromatin by RNA polymerase II. Proc Natl Acad Sci U S A. 2013 May 07; 110(19):7654-9. Hsieh FK, Kulaeva OI, Patel SS, Dyer PN, Luger K, Reinberg D, Studitsky VM. PMID: 23610384; PMCID: PMC3651417.
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    48. Switching from single-stranded to double-stranded DNA limits the unwinding processivity of ring-shaped T7 DNA helicase. Nucleic Acids Res. 2013 Apr; 41(7):4219-29. Jeong YJ, Rajagopal V, Patel SS. PMID: 23446275; PMCID: PMC3627605.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    49. Identification of I137M and other mutations that modulate incubation periods for two human prion strains. J Virol. 2012 Jun; 86(11):6033-41. Giles K, De Nicola GF, Patel S, Glidden DV, Korth C, Oehler A, DeArmond SJ, Prusiner SB. PMID: 22438549; PMCID: PMC3372217.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsPHPublic Health
    50. Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein. Proc Natl Acad Sci U S A. 2012 Feb 28; 109(9):3498-503. Watts JC, Giles K, Stöhr J, Oehler A, Bhardwaj S, Grillo SK, Patel S, DeArmond SJ, Prusiner SB. PMID: 22331873; PMCID: PMC3295307.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    51. Conserved properties of human and bovine prion strains on transmission to guinea pigs. Lab Invest. 2011 Sep; 91(9):1326-36. Safar JG, Giles K, Lessard P, Letessier F, Patel S, Serban A, Dearmond SJ, Prusiner SB. PMID: 21727894; PMCID: PMC3164925.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    52. Human prion strain selection in transgenic mice. Ann Neurol. 2010 Aug; 68(2):151-61. Giles K, Glidden DV, Patel S, Korth C, Groth D, Lemus A, DeArmond SJ, Prusiner SB. PMID: 20695008; PMCID: PMC2935907.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    53. Mitochondrial transcription factor Mtf1 traps the unwound non-template strand to facilitate open complex formation. J Biol Chem. 2010 Feb 05; 285(6):3949-3956. Paratkar S, Patel SS. PMID: 20008320; PMCID: PMC2824207.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    54. Real-time observation of the transition from transcription initiation to elongation of the RNA polymerase. Proc Natl Acad Sci U S A. 2009 Dec 29; 106(52):22175-80. Tang GQ, Roy R, Bandwar RP, Ha T, Patel SS. PMID: 20018723; PMCID: PMC2799739.
      View in: PubMed   Mentions:
    55. Single strand binding proteins increase the processivity of DNA unwinding by the hepatitis C virus helicase. J Mol Biol. 2008 Feb 08; 376(1):69-79. Rajagopal V, Patel SS. PMID: 18155046; PMCID: PMC2249756.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    56. Mechanisms of a ring shaped helicase. Nucleic Acids Res. 2006; 34(15):4216-24. Donmez I, Patel SS. PMID: 16935879; PMCID: PMC1616965.
      View in: PubMed   Mentions: 40     Fields:    Translation:Cells
    57. Sequential release of promoter contacts during transcription initiation to elongation transition. J Mol Biol. 2006 Jul 07; 360(2):466-83. Bandwar RP, Tang GQ, Patel SS. PMID: 16780876.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    58. Rapid binding of T7 RNA polymerase is followed by simultaneous bending and opening of the promoter DNA. Biochemistry. 2006 Apr 18; 45(15):4947-56. Tang GQ, Patel SS. PMID: 16605262.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    59. T7 RNA polymerase-induced bending of promoter DNA is coupled to DNA opening. Biochemistry. 2006 Apr 18; 45(15):4936-46. Tang GQ, Patel SS. PMID: 16605261.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    60. Human but not yeast CHD1 binds directly and selectively to histone H3 methylated at lysine 4 via its tandem chromodomains. J Biol Chem. 2005 Dec 23; 280(51):41789-92. Sims RJ, Chen CF, Santos-Rosa H, Kouzarides T, Patel SS, Reinberg D. PMID: 16263726; PMCID: PMC1421377.
      View in: PubMed   Mentions: 195     Fields:    Translation:HumansCells
    61. DNA synthesis provides the driving force to accelerate DNA unwinding by a helicase. Nature. 2005 May 19; 435(7040):370-3. Stano NM, Jeong YJ, Donmez I, Tummalapalli P, Levin MK, Patel SS. PMID: 15902262; PMCID: PMC1563444.
      View in: PubMed   Mentions: 102     Fields:    Translation:Cells
    62. A Brownian motor mechanism of translocation and strand separation by hepatitis C virus helicase. Nat Struct Mol Biol. 2005 May; 12(5):429-35. Levin MK, Gurjar M, Patel SS. PMID: 15806107.
      View in: PubMed   Mentions: 58     Fields:    Translation:Cells
    63. The DNA-unwinding mechanism of the ring helicase of bacteriophage T7. Proc Natl Acad Sci U S A. 2004 May 11; 101(19):7264-9. Jeong YJ, Levin MK, Patel SS. PMID: 15123793; PMCID: PMC409907.
      View in: PubMed   Mentions: 50     Fields:    Translation:Cells
    64. Fluorescence methods for studying the kinetics and thermodynamics of transcription initiation. Methods Enzymol. 2003; 370:668-86. Patel SS, Bandwar RP. PMID: 14712683.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    65. The energetics of consensus promoter opening by T7 RNA polymerase. J Mol Biol. 2002 Nov 15; 324(1):63-72. Bandwar RP, Patel SS. PMID: 12421559.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    66. T7 DNA helicase: a molecular motor that processively and unidirectionally translocates along single-stranded DNA. J Mol Biol. 2002 Aug 30; 321(5):807-19. Kim DE, Narayan M, Patel SS. PMID: 12206763.
      View in: PubMed   Mentions: 50     Fields:    Translation:Cells
    67. The intercalating beta-hairpin of T7 RNA polymerase plays a role in promoter DNA melting and in stabilizing the melted DNA for efficient RNA synthesis. J Mol Biol. 2002 Feb 01; 315(5):1009-25. Stano NM, Patel SS. PMID: 11827472.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
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