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Ursula Heilmeier, MD

Title(s)TICR Graduate Programs, Radiology
SchoolSchool of Medicine
Address85 Berry Street
San Francisco CA 94107
Phone415-353-4933
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    Collapse Awards and Honors
    American Society for Bone and Mineral Research2016ASBMR Young Investigator Award
    European Calcified Tissue Society2016ECTS New Investigator Award
    International Society for Clinical Densitometry2019Best Clinician Abstract Award
    European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and MSK Diseases 2019ESCEO-AgNovos Healthcare Young Investigator Award

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    Ursula Heilmeier studied medicine at the University of Regensburg Medical School, Germany funded through a scholarship from the German National Academic Foundation (Studienstiftung des Deutschen Volkes). After graduating from Medical School in 2008 she started her residency training in radiology at the Ludwig Maximilian University (LMU) hospital in Munich. In 2012, she finished her doctoral thesis (Dr.med.) summa cum laude; in her thesis she investigated macrophage and dendritic cell differentiation. In the same year she joined MQIR at UCSF as a postdoctoral scholar to study musculoskeletal aging. Her research work centers around bone and cartilage health and senescence, with an emphasis on diabetic bone disease and osteoarthritis. She received several awards for her work on diabetic bone disease including the ASBMR Young Investigator Award, the ECTS New Investigator Award as well as awards from the ESCEO and the ISCD.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Infrapatellar fat pad abnormalities are associated with a higher inflammatory synovial fluid cytokine profile in young adults following ACL tear. Osteoarthritis Cartilage. 2020 01; 28(1):82-91. Heilmeier U, Mamoto K, Amano K, Eck B, Tanaka M, Bullen JA, Schwaiger BJ, Huebner JL, Stabler TV, Kraus VB, Ma CB, Link TM, Li X. PMID: 31526878.
      View in: PubMed   Mentions: 2     Fields:    
    2. Structural Changes over a Short Period Are Associated with Functional Assessments in Rheumatoid Arthritis. J Rheumatol. 2019 07; 46(7):676-684. Shimizu T, Cruz A, Tanaka M, Mamoto K, Pedoia V, Burghardt AJ, Heilmeier U, Link TM, Graf J, Imboden JB, Li X. PMID: 30770506.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Central osteophytes develop in cartilage with abnormal structure and composition: data from the Osteoarthritis Initiative cohort. Skeletal Radiol. 2019 Sep; 48(9):1357-1365. Kretzschmar M, Heilmeier U, Foreman SC, Joseph GB, McCulloch CE, Nevitt MC, Link TM. PMID: 30739145.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Diabetics show accelerated progression of knee cartilage and meniscal lesions: data from the osteoarthritis initiative. Skeletal Radiol. 2019 Jun; 48(6):919-930. Neumann J, Guimaraes JB, Heilmeier U, Joseph GB, Nevitt MC, McCulloch CE, Link TM. PMID: 30357451.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    5. Baseline knee joint effusion and medial femoral bone marrow edema, in addition to MRI-based T2 relaxation time and texture measurements of knee cartilage, can help predict incident total knee arthroplasty 4-7 years later: data from the Osteoarthritis Initiative. Skeletal Radiol. 2019 Jan; 48(1):89-101. Heilmeier U, Wamba JM, Joseph GB, Darakananda K, Callan J, Neumann J, Link TM. PMID: 29961091.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. Tool for osteoarthritis risk prediction (TOARP) over 8 years using baseline clinical data, X-ray, and MRI: Data from the osteoarthritis initiative. J Magn Reson Imaging. 2018 06; 47(6):1517-1526. Joseph GB, McCulloch CE, Nevitt MC, Neumann J, Gersing AS, Kretzschmar M, Schwaiger BJ, Lynch JA, Heilmeier U, Lane NE, Link TM. PMID: 29143404.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    7. Assessment of 3-month changes in bone microstructure under anti-TNFa therapy in patients with rheumatoid arthritis using high-resolution peripheral quantitative computed tomography (HR-pQCT). Arthritis Res Ther. 2017 Oct 04; 19(1):222. Shimizu T, Choi HJ, Heilmeier U, Tanaka M, Burghardt AJ, Gong J, Chanchek N, Link TM, Graf J, Imboden JB, Li X. PMID: 28978352.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    8. Conservatively treated knee injury is associated with knee cartilage matrix degeneration measured with MRI-based T2 relaxation times: data from the osteoarthritis initiative. Skeletal Radiol. 2018 Jan; 47(1):93-106. Hofmann FC, Neumann J, Heilmeier U, Joseph GB, Nevitt MC, McCulloch CE, Link TM. PMID: 28852821.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Association of diabetes mellitus and biochemical knee cartilage composition assessed by T2 relaxation time measurements: Data from the osteoarthritis initiative. J Magn Reson Imaging. 2018 02; 47(2):380-390. Chanchek N, Gersing AS, Schwaiger BJ, Nevitt MC, Neumann J, Joseph GB, Lane NE, Zarnowski J, Hofmann FC, Heilmeier U, McCulloch CE, Link TM. PMID: 28556419.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    10. Medial femur T2 Z-scores predict the probability of knee structural worsening over 4-8 years: Data from the osteoarthritis initiative. J Magn Reson Imaging. 2017 10; 46(4):1128-1136. Joseph GB, McCulloch CE, Nevitt MC, Gersing AS, Schwaiger BJ, Kretzschmar M, Heilmeier U, Link TM. PMID: 28206712.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. Bone Quality-Beyond Bone Mineral Density. Semin Musculoskelet Radiol. 2016 Jul; 20(3):269-278. Link TM, Heilmeier U. PMID: 27741542.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. Diabetes and Bone. Semin Musculoskelet Radiol. 2016 Jul; 20(3):300-304. Heilmeier U, Patsch JM. PMID: 27741545.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Evaluation of Chondrocalcinosis and Associated Knee Joint Degeneration Using MR Imaging: Data from the Osteoarthritis Initiative. Eur Radiol. 2017 Jun; 27(6):2497-2506. Gersing AS, Schwaiger BJ, Heilmeier U, Joseph GB, Facchetti L, Kretzschmar M, Lynch JA, McCulloch CE, Nevitt MC, Steinbach LS, Link TM. PMID: 27704199.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    14. Serum microRNAs are indicative of skeletal fractures in postmenopausal women with and without type 2 diabetes and influence osteogenic and adipogenic differentiation of adipose-tissue derived mesenchymal stem cells in vitro. J Bone Miner Res 2016 Jun 27. doi: 10.1002/jbmr.2897 [Epub ahead of print]. 2016.
    15. Cortical bone laminar analysis reveals increased midcortical and periosteal porosity in type 2 diabetic postmenopausal women with history of fragility fractures compared to fracture-free diabetics. Osteoporos Int. 2016 Sep;27(9):2791-802, [Epub ahead of print]. 2016. Heilmeier U., Cheng K., Pasco C., Parrish R., Nirody J., Patsch JM., Zhang CA., Joseph GB., Burghardt AJ., Schwartz AV., Link TM., Kazakia, GJ.
    16. Semin Musculoskelet Radiol. Diabetes and Bone. 2016; 3(20):300-304. Heilmeier U, Patsch JM.
    17. Eur Radiol. 2016 Oct 4. [Epub ahead of print]. 2016.
    18. Evaluating radiocarpal cartilage matrix changes 3-months after anti-TNF treatment for rheumatoid arthritis using MR T1? imaging. J Magn Reson Imaging. 2017 05; 45(5):1514-1522. Ku E, Pedoia V, Tanaka M, Heilmeier U, Imboden J, Graf J, Link T, Li X. PMID: 27661002.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    19. Magnetic resonance imaging lesions are more severe and cartilage T2 relaxation time measurements are higher in isolated lateral compartment radiographic knee osteoarthritis than in isolated medial compartment disease - data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2017 01; 25(1):85-93. Wise BL, Niu J, Guermazi A, Liu F, Heilmeier U, Ku E, Lynch JA, Zhang Y, Felson DT, Kwoh CK, Lane NE. PMID: 27539891.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    20. Role of thigh muscle cross-sectional area and strength in progression of knee cartilage degeneration over 48 months - data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2016 12; 24(12):2082-2091. Goldman LH, Tang K, Facchetti L, Heilmeier U, Joseph GB, Nevitt MC, McCulloch CE, Souza RB, Link TM. PMID: 27457100.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. Semin Musculoskelet Radiol. 2016; 3(20):269-278.
    22. Longitudinal analysis of cartilage T2 relaxation times and joint degeneration in African American and Caucasian American women over an observation period of 6 years - data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2016 08; 24(8):1384-91. Kretzschmar M, Heilmeier U, Yu A, Joseph GB, Liu F, Solka M, McCulloch CE, Nevitt MC, Link TM. PMID: 26970285.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    23. MRI findings associated with development of incident knee pain over 48 months: data from the osteoarthritis initiative. Skeletal Radiol. 2016 May; 45(5):653-60. Joseph GB, Hou SW, Nardo L, Heilmeier U, Nevitt MC, McCulloch CE, Link TM. PMID: 26919860.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    24. Osteoporosis Imaging in the Geriatric Patient. Curr Radiol Rep. 2016 Apr; 4(4). Heilmeier U, Youm J, Torabi S, Link TM. PMID: 27482472.
      View in: PubMed   Mentions:
    25. Progression of cartilage degeneration and clinical symptoms in obese and overweight individuals is dependent on the amount of weight loss: 48-month data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2016 07; 24(7):1126-34. Gersing AS, Solka M, Joseph GB, Schwaiger BJ, Heilmeier U, Feuerriegel G, Nevitt MC, McCulloch CE, Link TM. PMID: 26828356.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    26. High-temporospatial-resolution dynamic contrast-enhanced (DCE) wrist MRI with variable-density pseudo-random circular Cartesian undersampling (CIRCUS) acquisition: evaluation of perfusion in rheumatoid arthritis patients. NMR Biomed. 2016 Jan; 29(1):15-23. Liu J, Pedoia V, Heilmeier U, Ku E, Su F, Khanna S, Imboden J, Graf J, Link T, Li X. PMID: 26608949.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    27. Circulating microRNAs as novel biomarkers for bone diseases - Complex signatures for multifactorial diseases? Mol Cell Endocrinol. 2016 09 05; 432:83-95. Hackl M, Heilmeier U, Weilner S, Grillari J. PMID: 26525415.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimals
    28. Femoral condyle insufficiency fractures: associated clinical and morphological findings and impact on outcome. Skeletal Radiol. 2015 Dec; 44(12):1785-94. Plett SK, Hackney LA, Heilmeier U, Nardo L, Yu A, Zhang CA, Link TM. PMID: 26290325.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. Osteoarthritis Cartilage. Racial differences in biochemical knee cartilage composition between African-American and Caucasian-American women with 3Tesla MR-based T2 relaxation time measurements - Data from the Osteoarthritis Initiative. 2015; S1063-4584(15)01143-7. Yu A*, Heilmeier U* (* shared first authors), Kretzschmar M, Joseph GB, Liu F, Liebl H, McCulloch CE, Nevitt MC, Lane NE, Link TM. .
    30. Volumetric femoral BMD, bone geometry, and serum sclerostin levels differ between type 2 diabetic postmenopausal women with and without fragility fractures. Osteoporos Int. 2015 Apr; 26(4):1283-93. Heilmeier U, Carpenter DR, Patsch JM, Harnish R, Joseph GB, Burghardt AJ, Baum T, Schwartz AV, Lang TF, Link TM. PMID: 25582311.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    31. In vitro assessment of knee MRI in the presence of metal implants comparing MAVRIC-SL and conventional fast spin echo sequences at 1.5 and 3 T field strength. J Magn Reson Imaging. 2015 May; 41(5):1291-9. Liebl H, Heilmeier U, Lee S, Nardo L, Patsch J, Schuppert C, Han M, Rondak IC, Banerjee S, Koch K, Link TM, Krug R. PMID: 24912802.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    32. Early T2 changes predict onset of radiographic knee osteoarthritis: data from the osteoarthritis initiative. Ann Rheum Dis. 2015 Jul; 74(7):1353-9. Liebl H, Joseph G, Nevitt MC, Singh N, Heilmeier U, Subburaj K, Jungmann PM, McCulloch CE, Lynch JA, Lane NE, Link TM. PMID: 24615539.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    33. Kretzschmar M., Nardo L., Han MM., Heilmeier U., Sam C., Joseph GB., Koch KM., Krug R., Link TM. Metal artefact suppression at 3 T MRI: comparison of MAVRIC-SL with conventional fast spin echo sequences in patients with Hip joint arthroplasty. Eur Radiol. 2015 Feb 14.
    34. Joseph GB., McCulloch CE., Nevitt MC., Heilmeier U., Nardo L., Lynch JA., Liu F., Baum T., Link TM. A Reference Database of Cartilage 3 Tesla MRI T2 Values in Knees without Diagnostic Evidence of Cartilage Degeneration: Data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2015 Feb 10.
    35. Lance V., Heilmeier UR., Joseph GB., Steinbach L., Ma B., Link TM. MR imaging characteristics and clinical symptoms related to displaced meniscal flap tears. Skeletal Radiol. 2015 Mar; 44(3):375-84.
    36. Schuierer MM., Heilmeier U., Boettcher A., Ugocsai P., Bosserhoff AK., Schmitz G., Langmann T. Induction of Raf kinase inhibitor protein contributes to macrophage differentiation. Biochem Biophys Res Commun. 2006 Apr 21; 342(4):1083-7.
    37. Radiologe. 2010 Oct;50(10):902-6. doi: 10.1007/s00117-010-2067-9. German. An unusual case of non-traumatic enophthalmos. Heilmeier U, Decker C, Miller C, Hintschich C, Reiser MF, Mueller-Lisse UG.
    38. Kretzschmar M., Lin W., Nardo L., Joseph GB, Dunlop DD., Heilmeier U., Nevitt MC., Alizai H., McCulloch CE., Lynch JA., Link TM. Association of physical activity measured by accelerometer, knee joint abnormalities and cartilage T2-measurements obtained from 3T MRI: Data from the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2015 Mar 16.
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