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    Jon Levine, MD, PhD

    TitleProfessor
    SchoolUCSF School of Dentistry
    DepartmentOral & Maxillofacial Surgery
    Address521 Parnassus Ave, Clin. Sci.
    Phone415-476-5108

       Bibliographic 
       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Joseph EK, Green PG, Bogen O, Alvarez P, Levine JD. Vascular Endothelial Cells Mediate Mechanical Stimulation-Induced Enhancement of Endothelin Hyperalgesia via Activation of P2X2/3 Receptors on Nociceptors. J Neurosci. 2013 Feb 13; 33(7):2849-59.
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      2. Ferrari LF, Levine E, Levine JD. Role of a novel nociceptor autocrine mechanism in chronic pain. Eur J Neurosci. 2013 May; 37(10):1705-13.
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      3. Gear R, Becerra L, Upadhyay J, Bishop J, Wallin D, Pendse G, Levine J, Borsook D. Pain facilitation brain regions activated by nalbuphine are revealed by pharmacological FMRI. PLoS One. 2013; 8(1):e50169.
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      4. Miaskowski C, Cooper B, Paul SM, West C, Langford D, Levine JD, Abrams G, Hamolsky D, Dunn L, Dodd M, Neuhaus J, Baggott C, Dhruva A, Schmidt B, Cataldo J, Merriman J, Aouizerat BE. Identification of patient subgroups and risk factors for persistent breast pain following breast cancer surgery. J Pain. 2012 Dec; 13(12):1172-87.
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      5. Hendrich J, Alvarez P, Joseph EK, Ferrari LF, Chen X, Levine JD. In Vivo and in Vitro Comparison of Female and Male Nociceptors. J Pain. 2012 Dec; 13(12):1224-31.
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      6. Ferrari LF, Levine E, Levine JD. Independent contributions of alcohol and stress axis hormones to painful peripheral neuropathy. Neuroscience. 2013 Jan 3; 228:409-17.
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      7. Hucho T, Suckow V, Joseph EK, Kuhn J, Schmoranzer J, Dina OA, Chen X, Karst M, Bernateck M, Levine JD, Ropers HH. Ca++/CaMKII switches nociceptor-sensitizing stimuli into desensitizing stimuli. J Neurochem. 2012 Nov; 123(4):589-601.
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      8. Alvarez P, Chen X, Hendrich J, Irwin JC, Green PG, Giudice LC, Levine JD. Ectopic uterine tissue as a chronic pain generator. Neuroscience. 2012 Dec 6; 225:269-82.
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      9. Alvarez P, Chen X, Bogen O, Green PG, Levine JD. IB4(+) nociceptors mediate persistent muscle pain induced by GDNF. J Neurophysiol. 2012 Nov; 108(9):2545-53.
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      10. Ferrari LF, Bogen O, Alessandri-Haber N, Levine E, Gear RW, Levine JD. Transient decrease in nociceptor GRK2 expression produces long-term enhancement in inflammatory pain. Neuroscience. 2012 Oct 11; 222:392-403.
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      11. Hendrich J, Alvarez P, Chen X, Levine JD. GDNF induces mechanical hyperalgesia in muscle by reducing I(BK) in isolectin B4-positive nociceptors. Neuroscience. 2012 Sep 6; 219:204-13.
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      12. McCann B, Miaskowski C, Koetters T, Baggott C, West C, Levine JD, Elboim C, Abrams G, Hamolsky D, Dunn L, Rugo H, Dodd M, Paul SM, Neuhaus J, Cooper B, Schmidt B, Langford D, Cataldo J, Aouizerat BE. Associations between pro- and anti-inflammatory cytokine genes and breast pain in women prior to breast cancer surgery. J Pain. 2012 May; 13(5):425-37.
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      13. Illi J, Miaskowski C, Cooper B, Levine JD, Dunn L, West C, Dodd M, Dhruva A, Paul SM, Baggott C, Cataldo J, Langford D, Schmidt B, Aouizerat BE. Association between pro- and anti-inflammatory cytokine genes and a symptom cluster of pain, fatigue, sleep disturbance, and depression. Cytokine. 2012 Jun; 58(3):437-47.
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      14. Witsberger TH, Levine JM, Fosgate GT, Slater MR, Kerwin SC, Russell KE, Levine GJ. Associations between cerebrospinal fluid biomarkers and long-term neurologic outcome in dogs with acute intervertebral disk herniation. J Am Vet Med Assoc. 2012 Mar 1; 240(5):555-62.
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      15. Oaklander AL, Wilson PR, Moskovitz PA, Manning DC, Lubenow T, Levine JD, Harden RN, Galer BS, Cooper MS, Bruehl S, Broatch J, Berde C, Bennett GJ. Response to "A new definition of neuropathic pain". Pain. 2012 Apr; 153(4):934-5; author reply 935-6.
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      16. Bogen O, Alessandri-Haber N, Chu C, Gear RW, Levine JD. Generation of a pain memory in the primary afferent nociceptor triggered by PKCe activation of CPEB. J Neurosci. 2012 Feb 8; 32(6):2018-26.
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      17. Alvarez P, Gear RW, Green PG, Levine JD. IB4-saporin attenuates acute and eliminates chronic muscle pain in the rat. Exp Neurol. 2012 Feb; 233(2):859-65.
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      18. Joseph EK, Levine JD. Sexual dimorphism in endothelin-1 induced mechanical hyperalgesia in the rat. Exp Neurol. 2012 Jan; 233(1):505-12.
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      19. Green PG, Chen X, Alvarez P, Ferrari LF, Levine JD. Early-life stress produces muscle hyperalgesia and nociceptor sensitization in the adult rat. Pain. 2011 Nov; 152(11):2549-56.
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      20. Ferrari LF, Chum A, Bogen O, Reichling DB, Levine JD. Role of Drp1, a key mitochondrial fission protein, in neuropathic pain. J Neurosci. 2011 Aug 3; 31(31):11404-10.
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      21. Alvarez P, Ferrari LF, Levine JD. Muscle pain in models of chemotherapy-induced and alcohol-induced peripheral neuropathy. Ann Neurol. 2011 Jul; 70(1):101-9.
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      22. Goswami C, Kuhn J, Dina OA, Fernández-Ballester G, Levine JD, Ferrer-Montiel A, Hucho T. Estrogen destabilizes microtubules through an ion-conductivity-independent TRPV1 pathway. J Neurochem. 2011 Jun; 117(6):995-1008.
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      23. Chu C, Levine E, Gear RW, Bogen O, Levine JD. Mitochondrial dependence of nerve growth factor-induced mechanical hyperalgesia. Pain. 2011 Aug; 152(8):1832-7.
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      24. Chen X, Green PG, Levine JD. Abnormal muscle afferent function in a model of Taxol chemotherapy-induced painful neuropathy. J Neurophysiol. 2011 Jul; 106(1):274-9.
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      25. Chen X, Green PG, Levine JD. Stress enhances muscle nociceptor activity in the rat. Neuroscience. 2011 Jun 30; 185:166-73.
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      26. Green PG, Alvarez P, Gear RW, Mendoza D, Levine JD. Further validation of a model of fibromyalgia syndrome in the rat. J Pain. 2011 Jul; 12(7):811-8.
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      27. Gear RW, Levine JD. Nucleus accumbens facilitates nociception. Exp Neurol. 2011 Jun; 229(2):502-6.
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      28. Levine JM, Levine GJ, Porter BF, Topp K, Noble-Haeusslein LJ. Naturally occurring disk herniation in dogs: an opportunity for pre-clinical spinal cord injury research. J Neurotrauma. 2011 Apr; 28(4):675-88.
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      29. Dina OA, Levine JD, Green PG. Enhanced cytokine-induced mechanical hyperalgesia in skeletal muscle produced by a novel mechanism in rats exposed to unpredictable sound stress. Eur J Pain. 2011 Sep; 15(8):796-800.
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      30. Joseph EK, Gear RW, Levine JD. Mechanical stimulation enhances endothelin-1 hyperalgesia. Neuroscience. 2011 Mar 31; 178:189-95.
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      31. Park CJ, Zhao Z, Glidewell-Kenney C, Lazic M, Chambon P, Krust A, Weiss J, Clegg DJ, Dunaif A, Jameson JL, Levine JE. Genetic rescue of nonclassical ERa signaling normalizes energy balance in obese Era-null mutant mice. J Clin Invest. 2011 Feb; 121(2):604-12.
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      32. Reichling DB, Levine JD. Pain and death: neurodegenerative disease mechanisms in the nociceptor. Ann Neurol. 2011 Jan; 69(1):13-21.
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      33. Andres C, Meyer S, Dina OA, Levine JD, Hucho T. Quantitative automated microscopy (QuAM) elucidates growth factor specific signalling in pain sensitization. Mol Pain. 2010; 6:98.
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      34. Lazic M, Aird F, Levine JE, Dunaif A. Prenatal androgen treatment alters body composition and glucose homeostasis in male rats. J Endocrinol. 2011 Mar; 208(3):293-300.
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      35. Mayer C, Acosta-Martinez M, Dubois SL, Wolfe A, Radovick S, Boehm U, Levine JE. Timing and completion of puberty in female mice depend on estrogen receptor alpha-signaling in kisspeptin neurons. Proc Natl Acad Sci U S A. 2010 Dec 28; 107(52):22693-8.
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      36. Ferrari LF, Gear RW, Levine JD. Attenuation of activity in an endogenous analgesia circuit by ongoing pain in the rat. J Neurosci. 2010 Oct 13; 30(41):13699-706.
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      37. Chen X, Green PG, Levine JD. Neuropathic pain-like alterations in muscle nociceptor function associated with vibration-induced muscle pain. Pain. 2010 Nov; 151(2):460-6.
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      38. Joseph EK, Levine JD. Mu and delta opioid receptors on nociceptors attenuate mechanical hyperalgesia in rat. Neuroscience. 2010 Nov 24; 171(1):344-50.
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      39. Ferrari LF, Levine JD. Alcohol consumption enhances antiretroviral painful peripheral neuropathy by mitochondrial mechanisms. Eur J Neurosci. 2010 Sep; 32(5):811-8.
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      40. Alvarez P, Levine JD, Green PG. Eccentric exercise induces chronic alterations in musculoskeletal nociception in the rat. Eur J Neurosci. 2010 Sep; 32(5):819-25.
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      41. Joseph EK, Levine JD. Hyperalgesic priming is restricted to isolectin B4-positive nociceptors. Neuroscience. 2010 Aug 11; 169(1):431-5.
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      42. Joseph EK, Levine JD. Multiple PKCe-dependent mechanisms mediating mechanical hyperalgesia. Pain. 2010 Jul; 150(1):17-21.
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      43. Joseph EK, Reichling DB, Levine JD. Shared mechanisms for opioid tolerance and a transition to chronic pain. J Neurosci. 2010 Mar 31; 30(13):4660-6.
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      44. Dina OA, Joseph EK, Levine JD, Green PG. Mechanisms mediating vibration-induced chronic musculoskeletal pain analyzed in the rat. J Pain. 2010 Apr; 11(4):369-77.
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      45. Ferrari LF, Bogen O, Levine JD. Nociceptor subpopulations involved in hyperalgesic priming. Neuroscience. 2010 Feb 3; 165(3):896-901.
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      46. Schatzberg SJ, Li Q, Porter BF, Barber RM, Claiborne MK, Levine JM, Levine GJ, Israel SK, Young BD, Kiupel M, Greene C, Ruone S, Anderson L, Tong S. Broadly reactive pan-paramyxovirus reverse transcription polymerase chain reaction and sequence analysis for the detection of Canine distemper virus in a case of canine meningoencephalitis of unknown etiology. J Vet Diagn Invest. 2009 Nov; 21(6):844-9.
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      47. Reichling DB, Levine JD. Critical role of nociceptor plasticity in chronic pain. Trends Neurosci. 2009 Dec; 32(12):611-8.
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      48. Adler PB, Leiker J, Levine JM. Direct and indirect effects of climate change on a prairie plant community. PLoS One. 2009; 4(9):e6887.
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      49. Gear RW, Levine JD. Rostral ventral medulla cholinergic mechanism in pain-induced analgesia. Neurosci Lett. 2009 Oct 30; 464(3):170-2.
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      50. Gottsch ML, Navarro VM, Zhao Z, Glidewell-Kenney C, Weiss J, Jameson JL, Clifton DK, Levine JE, Steiner RA. Regulation of Kiss1 and dynorphin gene expression in the murine brain by classical and nonclassical estrogen receptor pathways. J Neurosci. 2009 Jul 22; 29(29):9390-5.
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      51. Khasar SG, Dina OA, Green PG, Levine JD. Sound stress-induced long-term enhancement of mechanical hyperalgesia in rats is maintained by sympathoadrenal catecholamines. J Pain. 2009 Oct; 10(10):1073-7.
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      52. Acosta-Martínez M, Luo J, Elias C, Wolfe A, Levine JE. Male-biased effects of gonadotropin-releasing hormone neuron-specific deletion of the phosphoinositide 3-kinase regulatory subunit p85alpha on the reproductive axis. Endocrinology. 2009 Sep; 150(9):4203-12.
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      53. Alessandri-Haber N, Dina OA, Chen X, Levine JD. TRPC1 and TRPC6 channels cooperate with TRPV4 to mediate mechanical hyperalgesia and nociceptor sensitization. J Neurosci. 2009 May 13; 29(19):6217-28.
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      54. Tambeli CH, Levine JD, Gear RW. Centralization of noxious stimulus-induced analgesia (NSIA) is related to activity at inhibitory synapses in the spinal cord. Pain. 2009 Jun; 143(3):228-32.
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      55. Zhao Z, Park C, McDevitt MA, Glidewell-Kenney C, Chambon P, Weiss J, Jameson JL, Levine JE. p21-Activated kinase mediates rapid estradiol-negative feedback actions in the reproductive axis. Proc Natl Acad Sci U S A. 2009 Apr 28; 106(17):7221-6.
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      56. Dina OA, Khasar SG, Gear RW, Levine JD. Activation of Gi induces mechanical hyperalgesia poststress or inflammation. Neuroscience. 2009 May 5; 160(2):501-7.
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      57. Joseph EK, Levine JD. Comparison of oxaliplatin- and cisplatin-induced painful peripheral neuropathy in the rat. J Pain. 2009 May; 10(5):534-41.
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      58. Bogen O, Dina OA, Gear RW, Levine JD. Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican. Neuroscience. 2009 Mar 17; 159(2):780-6.
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      59. Brown AS, Levine JD, Green PG. Sexual dimorphism in the effect of sound stress on neutrophil function. J Neuroimmunol. 2008 Dec 15; 205(1-2):25-31.
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      60. McDevitt MA, Thorsness RJ, Levine JE. A role for ATP-sensitive potassium channels in male sexual behavior. Horm Behav. 2009 Feb; 55(2):366-74.
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      61. Dina OA, Khasar SG, Alessandri-Haber N, Bogen O, Chen X, Green PG, Reichling DB, Messing RO, Levine JD. Neurotoxic catecholamine metabolite in nociceptors contributes to painful peripheral neuropathy. Eur J Neurosci. 2008 Sep; 28(6):1180-90.
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      62. Bogen O, Joseph EK, Chen X, Levine JD. GDNF hyperalgesia is mediated by PLCgamma, MAPK/ERK, PI3K, CDK5 and Src family kinase signaling and dependent on the IB4-binding protein versican. Eur J Neurosci. 2008 Jul; 28(1):12-9.
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      63. Baltzer WI, McMichael MA, Hosgood GL, Kerwin SC, Levine JM, Steiner JM, Ruaux CG. Randomized, blinded, placebo-controlled clinical trial of N-acetylcysteine in dogs with spinal cord trauma from acute intervertebral disc disease. Spine (Phila Pa 1976). 2008 Jun 1; 33(13):1397-402.
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      64. Khasar SG, Burkham J, Dina OA, Brown AS, Bogen O, Alessandri-Haber N, Green PG, Reichling DB, Levine JD. Stress induces a switch of intracellular signaling in sensory neurons in a model of generalized pain. J Neurosci. 2008 May 28; 28(22):5721-30.
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      65. Kuhn J, Dina OA, Goswami C, Suckow V, Levine JD, Hucho T. GPR30 estrogen receptor agonists induce mechanical hyperalgesia in the rat. Eur J Neurosci. 2008 Apr; 27(7):1700-9.
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      66. Joseph EK, Chen X, Bogen O, Levine JD. Oxaliplatin acts on IB4-positive nociceptors to induce an oxidative stress-dependent acute painful peripheral neuropathy. J Pain. 2008 May; 9(5):463-72.
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      67. Dina OA, Levine JD, Green PG. Muscle inflammation induces a protein kinase Cepsilon-dependent chronic-latent muscle pain. J Pain. 2008 May; 9(5):457-62.
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      68. Sughrue ME, Levine J, Barbaro NM. Pain as a symptom of peripheral nerve sheath tumors: clinical significance and future therapeutic directions. J Brachial Plex Peripher Nerve Inj. 2008; 3:6.
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      69. Huang W, Acosta-Martínez M, Levine JE. Ovarian steroids stimulate adenosine triphosphate-sensitive potassium (KATP) channel subunit gene expression and confer responsiveness of the gonadotropin-releasing hormone pulse generator to KATP channel modulation. Endocrinology. 2008 May; 149(5):2423-32.
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      70. Alessandri-Haber N, Dina OA, Joseph EK, Reichling DB, Levine JD. Interaction of transient receptor potential vanilloid 4, integrin, and SRC tyrosine kinase in mechanical hyperalgesia. J Neurosci. 2008 Jan 30; 28(5):1046-57.
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      71. Gear RW, Gordon NC, Hossaini-Zadeh M, Lee JS, Miaskowski C, Paul SM, Levine JD. A subanalgesic dose of morphine eliminates nalbuphine anti-analgesia in postoperative pain. J Pain. 2008 Apr; 9(4):337-41.
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      72. Dina OA, Green PG, Levine JD. Role of interleukin-6 in chronic muscle hyperalgesic priming. Neuroscience. 2008 Mar 18; 152(2):521-5.
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      73. Dina OA, Khasar SG, Alessandri-Haber N, Green PG, Messing RO, Levine JD. Alcohol-induced stress in painful alcoholic neuropathy. Eur J Neurosci. 2008 Jan; 27(1):83-92.
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      74. Chen X, Alessandri-Haber N, Levine JD. Marked attenuation of inflammatory mediator-induced C-fiber sensitization for mechanical and hypotonic stimuli in TRPV4-/- mice. Mol Pain. 2007; 3:31.
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      75. Belay AT, Scheiner R, So AK, Douglas SJ, Chakaborty-Chatterjee M, Levine JD, Sokolowski MB. The foraging gene of Drosophila melanogaster: spatial-expression analysis and sucrose responsiveness. J Comp Neurol. 2007 Oct 10; 504(5):570-82.
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      76. Zhang C, Bosch MA, Levine JE, Rønnekleiv OK, Kelly MJ. Gonadotropin-releasing hormone neurons express K(ATP) channels that are regulated by estrogen and responsive to glucose and metabolic inhibition. J Neurosci. 2007 Sep 19; 27(38):10153-64.
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      77. Gordon AT, Levine JD, Dubois MY, D'Angelo R, Conlon AM, Levacic D, Lebovits A. Open-label exploration of an intravenous nalbuphine and naloxone mixture as an analgesic agent following gynecologic surgery. Pain Med. 2007 Sep; 8(6):525-30.
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      78. Summer GJ, Dina OA, Levine JD. Enhanced inflammatory hyperalgesia after recovery from burn injury. Burns. 2007 Dec; 33(8):1021-6.
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      79. McDevitt MA, Glidewell-Kenney C, Weiss J, Chambon P, Jameson JL, Levine JE. Estrogen response element-independent estrogen receptor (ER)-alpha signaling does not rescue sexual behavior but restores normal testosterone secretion in male ERalpha knockout mice. Endocrinology. 2007 Nov; 148(11):5288-94.
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      80. Hucho T, Levine JD. Signaling pathways in sensitization: toward a nociceptor cell biology. Neuron. 2007 Aug 2; 55(3):365-76.
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      81. Summer GJ, Romero-Sandoval EA, Bogen O, Dina OA, Khasar SG, Levine JD. Proinflammatory cytokines mediating burn-injury pain. Pain. 2008 Mar; 135(1-2):98-107.
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      82. de Coupade C, Brown AS, Dazin PF, Levine JD, Green PG. beta(2)-Adrenergic receptor-dependent sexual dimorphism for murine leukocyte migration. J Neuroimmunol. 2007 May; 186(1-2):54-62.
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      83. Summer GJ, Puntillo KA, Miaskowski C, Green PG, Levine JD. Burn injury pain: the continuing challenge. J Pain. 2007 Jul; 8(7):533-48.
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      84. Joseph EK, Bogen O, Alessandri-Haber N, Levine JD. PLC-beta 3 signals upstream of PKC epsilon in acute and chronic inflammatory hyperalgesia. Pain. 2007 Nov; 132(1-2):67-73.
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      85. Chen X, Levine JD. Mechanically-evoked C-fiber activity in painful alcohol and AIDS therapy neuropathy in the rat. Mol Pain. 2007; 3:5.
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      86. Levine JD, Alessandri-Haber N. TRP channels: targets for the relief of pain. Biochim Biophys Acta. 2007 Aug; 1772(8):989-1003.
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      87. Dina OA, Gear RW, Messing RO, Levine JD. Severity of alcohol-induced painful peripheral neuropathy in female rats: role of estrogen and protein kinase (A and Cepsilon). Neuroscience. 2007 Mar 2; 145(1):350-6.
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      88. Summer GJ, Puntillo KA, Miaskowski C, Dina OA, Green PG, Levine JD. TrkA and PKC-epsilon in thermal burn-induced mechanical hyperalgesia in the rat. J Pain. 2006 Dec; 7(12):884-91.
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      89. Grant AD, Cottrell GS, Amadesi S, Trevisani M, Nicoletti P, Materazzi S, Altier C, Cenac N, Zamponi GW, Bautista-Cruz F, Lopez CB, Joseph EK, Levine JD, Liedtke W, Vanner S, Vergnolle N, Geppetti P, Bunnett NW. Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice. J Physiol. 2007 Feb 1; 578(Pt 3):715-33.
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      90. Paredes J, Szeto A, Levine JE, Zaias J, Gonzales JA, Mendez AJ, Llabre MM, Schneiderman N, McCabe PM. Social experience influences hypothalamic oxytocin in the WHHL rabbit. Psychoneuroendocrinology. 2006 Oct; 31(9):1062-75.
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      91. McCarter GC, Levine JD. Ionic basis of a mechanotransduction current in adult rat dorsal root ganglion neurons. Mol Pain. 2006; 2:28.
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      92. Hucho TB, Dina OA, Kuhn J, Levine JD. Estrogen controls PKCepsilon-dependent mechanical hyperalgesia through direct action on nociceptive neurons. Eur J Neurosci. 2006 Jul; 24(2):527-34.
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      93. Dina OA, Messing RO, Levine JD. Ethanol withdrawal induces hyperalgesia mediated by PKCepsilon. Eur J Neurosci. 2006 Jul; 24(1):197-204.
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      94. Levine JD, Khasar SG, Green PG. Neurogenic inflammation and arthritis. Ann N Y Acad Sci. 2006 Jun; 1069:155-67.
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      95. Alessandri-Haber N, Dina OA, Joseph EK, Reichling D, Levine JD. A transient receptor potential vanilloid 4-dependent mechanism of hyperalgesia is engaged by concerted action of inflammatory mediators. J Neurosci. 2006 Apr 5; 26(14):3864-74.
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      96. Gear RW, Lee JS, Miaskowski C, Gordon NC, Paul SM, Levine JD. Neuroleptics antagonize nalbuphine antianalgesia. J Pain. 2006 Mar; 7(3):187-91.
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      97. Joseph EK, Levine JD. Mitochondrial electron transport in models of neuropathic and inflammatory pain. Pain. 2006 Mar; 121(1-2):105-14.
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      98. Levine JM, Ruaux CG, Bergman RL, Coates JR, Steiner JM, Williams DA. Matrix metalloproteinase-9 activity in the cerebrospinal fluid and serum of dogs with acute spinal cord trauma from intervertebral disk disease. Am J Vet Res. 2006 Feb; 67(2):283-7.
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      99. Alessandri-Haber N, Joseph E, Dina OA, Liedtke W, Levine JD. TRPV4 mediates pain-related behavior induced by mild hypertonic stimuli in the presence of inflammatory mediator. Pain. 2005 Nov; 118(1-2):70-9.
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      100. Foecking EM, Levine JE. Effects of experimental hyperandrogenemia on the female rat reproductive axis: suppression of progesterone-receptor messenger RNA expression in the brain and blockade of luteinizing hormone surges. Gend Med. 2005 Sep; 2(3):155-65.
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      101. Levine JD, Reichling DB. Fibromyalgia: the nerve of that disease. J Rheumatol Suppl. 2005 Aug; 75:29-37.
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      102. Barker LA, Dazin PF, Levine JD, Green PG. Sympathoadrenal-dependent sexually dimorphic effect of nonhabituating stress on in vivo neutrophil recruitment in the rat. Br J Pharmacol. 2005 Aug; 145(7):872-9.
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      103. Chen X, Levine JD. Epinephrine-induced excitation and sensitization of rat C-fiber nociceptors. J Pain. 2005 Jul; 6(7):439-46.
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      104. Khasar SG, Green PG, Levine JD. Repeated sound stress enhances inflammatory pain in the rat. Pain. 2005 Jul; 116(1-2):79-86.
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      105. Hucho TB, Dina OA, Levine JD. Epac mediates a cAMP-to-PKC signaling in inflammatory pain: an isolectin B4(+) neuron-specific mechanism. J Neurosci. 2005 Jun 29; 25(26):6119-26.
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      106. Khasar SG, Dina OA, Green PG, Levine JD. Estrogen regulates adrenal medullary function producing sexual dimorphism in nociceptive threshold and beta-adrenergic receptor-mediated hyperalgesia in the rat. Eur J Neurosci. 2005 Jun; 21(12):3379-86.
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      107. Malik-Hall M, Dina OA, Levine JD. Primary afferent nociceptor mechanisms mediating NGF-induced mechanical hyperalgesia. Eur J Neurosci. 2005 Jun; 21(12):3387-94.
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      108. Dina OA, Hucho T, Yeh J, Malik-Hall M, Reichling DB, Levine JD. Primary afferent second messenger cascades interact with specific integrin subunits in producing inflammatory hyperalgesia. Pain. 2005 May; 115(1-2):191-203.
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      109. Foecking EM, Szabo M, Schwartz NB, Levine JE. Neuroendocrine consequences of prenatal androgen exposure in the female rat: absence of luteinizing hormone surges, suppression of progesterone receptor gene expression, and acceleration of the gonadotropin-releasing hormone pulse generator. Biol Reprod. 2005 Jun; 72(6):1475-83.
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      110. Parada CA, Reichling DB, Levine JD. Chronic hyperalgesic priming in the rat involves a novel interaction between cAMP and PKCepsilon second messenger pathways. Pain. 2005 Jan; 113(1-2):185-90.
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      111. Green PG, Levine JD. Sexual dimorphism in the effect of nonhabituating stress on neurogenic plasma extravasation. Eur J Neurosci. 2005 Jan; 21(2):486-92.
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      112. Joseph EK, Levine JD. Caspase signalling in neuropathic and inflammatory pain in the rat. Eur J Neurosci. 2004 Dec; 20(11):2896-902.
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      113. Eilers H, Trilk SL, Lee SY, Xue Q, Jong BE, Moff I, Levine JD, Schumacher MA. Isolation of an mRNA binding protein homologue that is expressed in nociceptors. Eur J Neurosci. 2004 Nov; 20(9):2283-93.
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      114. de Coupade C, Gear RW, Dazin PF, Sroussi HY, Green PG, Levine JD. Beta 2-adrenergic receptor regulation of human neutrophil function is sexually dimorphic. Br J Pharmacol. 2004 Dec; 143(8):1033-41.
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      115. Alessandri-Haber N, Dina OA, Yeh JJ, Parada CA, Reichling DB, Levine JD. Transient receptor potential vanilloid 4 is essential in chemotherapy-induced neuropathic pain in the rat. J Neurosci. 2004 May 5; 24(18):4444-52.
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      116. Dina OA, Parada CA, Yeh J, Chen X, McCarter GC, Levine JD. Integrin signaling in inflammatory and neuropathic pain in the rat. Eur J Neurosci. 2004 Feb; 19(3):634-42.
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      117. Joseph EK, Chen X, Khasar SG, Levine JD. Novel mechanism of enhanced nociception in a model of AIDS therapy-induced painful peripheral neuropathy in the rat. Pain. 2004 Jan; 107(1-2):147-58.
        View in: PubMed
      118. Miao FJ, Green PG, Levine JD. Mechanosensitive duodenal afferents contribute to vagal modulation of inflammation in the rat. J Physiol. 2004 Jan 1; 554(Pt 1):227-35.
        View in: PubMed
      119. Miao FJ, Green PG, Benowitz N, Levine JD. Central terminals of nociceptors are targets for nicotine suppression of inflammation. Neuroscience. 2004; 123(3):777-84.
        View in: PubMed
      120. Tambeli CH, Quang P, Levine JD, Gear RW. Contribution of spinal inhibitory receptors in heterosegmental antinociception induced by noxious stimulation. Eur J Neurosci. 2003 Dec; 18(11):2999-3006.
        View in: PubMed
      121. Gear RW, Gordon NC, Miaskowski C, Paul SM, Heller PH, Levine JD. Dose ratio is important in maximizing naloxone enhancement of nalbuphine analgesia in humans. Neurosci Lett. 2003 Nov 6; 351(1):5-8.
        View in: PubMed
      122. Tambeli CH, Young A, Levine JD, Gear RW. Contribution of spinal glutamatergic mechanisms in heterosegmental antinociception induced by noxious stimulation. Pain. 2003 Nov; 106(1-2):173-9.
        View in: PubMed
      123. Miao FJ, Green P, Benowitz N, Levine JD. Vagal modulation of spinal nicotine-induced inhibition of the inflammatory response mediated by descending antinociceptive controls. Neuropharmacology. 2003 Oct; 45(5):605-11.
        View in: PubMed
      124. Joseph EK, Parada CA, Levine JD. Hyperalgesic priming in the rat demonstrates marked sexual dimorphism. Pain. 2003 Sep; 105(1-2):143-50.
        View in: PubMed
      125. Dina OA, McCarter GC, de Coupade C, Levine JD. Role of the sensory neuron cytoskeleton in second messenger signaling for inflammatory pain. Neuron. 2003 Aug 14; 39(4):613-24.
        View in: PubMed
      126. de Coupade C, Solito E, Levine JD. Dexamethasone enhances interaction of endogenous annexin 1 with L-selectin and triggers shedding of L-selectin in the monocytic cell line U-937. Br J Pharmacol. 2003 Sep; 140(1):133-45.
        View in: PubMed
      127. Alessandri-Haber N, Yeh JJ, Boyd AE, Parada CA, Chen X, Reichling DB, Levine JD. Hypotonicity induces TRPV4-mediated nociception in rat. Neuron. 2003 Jul 31; 39(3):497-511.
        View in: PubMed
      128. Khasar SG, Gear RW, Levine JD. Absence of nalbuphine anti-analgesia in the rat. Neurosci Lett. 2003 Jul 24; 345(3):165-8.
        View in: PubMed
      129. Schmidt BL, Gear RW, Levine JD. Response of neuropathic trigeminal pain to the combination of low-dose nalbuphine plus naloxone in humans. Neurosci Lett. 2003 Jun 5; 343(2):144-6.
        View in: PubMed
      130. Khasar SG, Miao FJ, Gear RW, Green PG, Levine JD. Vagal modulation of bradykinin-induced mechanical hyperalgesia in the female rat. J Pain. 2003 Jun; 4(5):278-83.
        View in: PubMed
      131. Khasar SG, Green PG, Gear RW, Isenberg W, Levine JD. Gonadal hormones do not account for sexual dimorphism in vagal modulation of nociception in the rat. J Pain. 2003 May; 4(4):190-6.
        View in: PubMed
      132. Parada CA, Yeh JJ, Joseph EK, Levine JD. Tumor necrosis factor receptor type-1 in sensory neurons contributes to induction of chronic enhancement of inflammatory hyperalgesia in rat. Eur J Neurosci. 2003 May; 17(9):1847-52.
        View in: PubMed
      133. Schmidt BL, Tambeli CH, Levine JD, Gear RW. Adaptations in nucleus accumbens circuitry during opioid withdrawal associated with persistence of noxious stimulus-induced antinociception in the rat. J Pain. 2003 Apr; 4(3):141-7.
        View in: PubMed
      134. Gear RW, Gordon NC, Miaskowski C, Paul SM, Heller PH, Levine JD. Sexual dimorphism in very low dose nalbuphine postoperative analgesia. Neurosci Lett. 2003 Mar 13; 339(1):1-4.
        View in: PubMed
      135. Khasar SG, Green PG, Miao FJ, Levine JD. Vagal modulation of nociception is mediated by adrenomedullary epinephrine in the rat. Eur J Neurosci. 2003 Feb; 17(4):909-15.
        View in: PubMed
      136. Strausbaugh HJ, Green PG, Dallman MF, Levine JD. Repeated, non-habituating stress suppresses inflammatory plasma extravasation by a novel, sympathoadrenal dependent mechanism. Eur J Neurosci. 2003 Feb; 17(4):805-12.
        View in: PubMed
      137. Tanner KD, Reichling DB, Gear RW, Paul SM, Levine JD. Altered temporal pattern of evoked afferent activity in a rat model of vincristine-induced painful peripheral neuropathy. Neuroscience. 2003; 118(3):809-17.
        View in: PubMed
      138. Harris GC, Levine JE. Pubertal acceleration of pulsatile gonadotropin-releasing hormone release in male rats as revealed by microdialysis. Endocrinology. 2003 Jan; 144(1):163-71.
        View in: PubMed
      139. Joseph EK, Levine JD. Sexual dimorphism for protein kinase c epsilon signaling in a rat model of vincristine-induced painful peripheral neuropathy. Neuroscience. 2003; 119(3):831-8.
        View in: PubMed
      140. Miao FJ, Jänig W, Jasmin L, Levine JD. Blockade of nociceptive inhibition of plasma extravasation by opioid stimulation of the periaqueductal gray and its interaction with vagus-induced inhibition in the rat. Neuroscience. 2003; 119(3):875-85.
        View in: PubMed
      141. Parada CA, Yeh JJ, Reichling DB, Levine JD. Transient attenuation of protein kinase Cepsilon can terminate a chronic hyperalgesic state in the rat. Neuroscience. 2003; 120(1):219-26.
        View in: PubMed
      142. Joseph EK, Levine JD. Sexual dimorphism in the contribution of protein kinase C isoforms to nociception in the streptozotocin diabetic rat. Neuroscience. 2003; 120(4):907-13.
        View in: PubMed
      143. Chen X, Levine JD. Altered temporal pattern of mechanically evoked C-fiber activity in a model of diabetic neuropathy in the rat. Neuroscience. 2003; 121(4):1007-15.
        View in: PubMed
      144. Khasar SG, Reichling DB, Green PG, Isenberg WM, Levine JD. Fasting is a physiological stimulus of vagus-mediated enhancement of nociception in the female rat. Neuroscience. 2003; 119(1):215-21.
        View in: PubMed
      145. Thompson CA, Russell KE, Levine JM, Weeks BR. Cerebrospinal fluid from a dog with neurologic collapse. Vet Clin Pathol. 2003; 32(3):143-6.
        View in: PubMed
      146. Aley O, Levine JD. Contribution of 5- and 12-lipoxygenase products to mechanical hyperalgesia induced by prostaglandin E(2) and epinephrine in the rat. Exp Brain Res. 2003 Feb; 148(4):482-7.
        View in: PubMed
      147. Baron R, Fields HL, Jänig W, Kitt C, Levine JD. National Institutes of Health Workshop: reflex sympathetic dystrophy/complex regional pain syndromes--state-of-the-science. Anesth Analg. 2002 Dec; 95(6):1812-6.
        View in: PubMed
      148. Khasar SG, Miao FJ, Gear RW, Green PG, Isenberg WM, Levine JD. Sympathetic-independent bradykinin mechanical hyperalgesia induced by subdiaphragmatic vagotomy in the rat. J Pain. 2002 Oct; 3(5):369-76.
        View in: PubMed
      149. Tambeli CH, Parada CA, Levine JD, Gear RW. Inhibition of tonic spinal glutamatergic activity induces antinociception in the rat. Eur J Neurosci. 2002 Oct; 16(8):1547-53.
        View in: PubMed
      150. Schmidt BL, Tambeli CH, Barletta J, Luo L, Green P, Levine JD, Gear RW. Altered nucleus accumbens circuitry mediates pain-induced antinociception in morphine-tolerant rats. J Neurosci. 2002 Aug 1; 22(15):6773-80.
        View in: PubMed
      151. Shin J, Cho H, Hwang SW, Jung J, Shin CY, Lee SY, Kim SH, Lee MG, Choi YH, Kim J, Haber NA, Reichling DB, Khasar S, Levine JD, Oh U. Bradykinin-12-lipoxygenase-VR1 signaling pathway for inflammatory hyperalgesia. Proc Natl Acad Sci U S A. 2002 Jul 23; 99(15):10150-5.
        View in: PubMed
      152. Schmidt BL, Tambeli CH, Levine JD, Gear RW. mu/delta Cooperativity and opposing kappa-opioid effects in nucleus accumbens-mediated antinociception in the rat. Eur J Neurosci. 2002 Mar; 15(5):861-8.
        View in: PubMed
      153. Aley KO, Levine JD. Different peripheral mechanisms mediate enhanced nociception in metabolic/toxic and traumatic painful peripheral neuropathies in the rat. Neuroscience. 2002; 111(2):389-97.
        View in: PubMed
      154. Green PG, Dahlqvist SR, Isenberg WM, Miao FJ, Levine JD. Role of adrenal medulla in development of sexual dimorphism in inflammation. Eur J Neurosci. 2001 Nov; 14(9):1436-44.
        View in: PubMed
      155. Aley KO, Martin A, McMahon T, Mok J, Levine JD, Messing RO. Nociceptor sensitization by extracellular signal-regulated kinases. J Neurosci. 2001 Sep 1; 21(17):6933-9.
        View in: PubMed
      156. Aley KO, Levine JD. Rapid onset pain induced by intravenous streptozotocin in the rat. J Pain. 2001 Jun; 2(3):146-50.
        View in: PubMed
      157. Dina OA, Aley KO, Isenberg W, Messing RO, Levine JD. Sex hormones regulate the contribution of PKCepsilon and PKA signalling in inflammatory pain in the rat. Eur J Neurosci. 2001 Jun; 13(12):2227-33.
        View in: PubMed
      158. Miao FJ, Jänig W, Jasmin L, Levine JD. Spino-bulbo-spinal pathway mediating vagal modulation of nociceptive-neuroendocrine control of inflammation in the rat. J Physiol. 2001 May 1; 532(Pt 3):811-22.
        View in: PubMed
      159. Miao FJ, Benowitz NL, Levine JD. Endogenous opioids suppress activation of nociceptors by sub-nanomolar nicotine. Br J Pharmacol. 2001 May; 133(1):23-8.
        View in: PubMed
      160. Khasar SG, Isenberg WM, Miao FJ, Gear RW, Green PG, Levine JD. Gender and gonadal hormone effects on vagal modulation of tonic nociception. J Pain. 2001 Apr; 2(2):91-100.
        View in: PubMed
      161. Dina OA, Chen X, Reichling D, Levine JD. Role of protein kinase Cepsilon and protein kinase A in a model of paclitaxel-induced painful peripheral neuropathy in the rat. Neuroscience. 2001; 108(3):507-15.
        View in: PubMed
      162. Schmidt BL, Tambeli CH, Gear RW, Levine JD. Nicotine withdrawal hyperalgesia and opioid-mediated analgesia depend on nicotine receptors in nucleus accumbens. Neuroscience. 2001; 106(1):129-36.
        View in: PubMed
      163. Chen X, Levine JD. Hyper-responsivity in a subset of C-fiber nociceptors in a model of painful diabetic neuropathy in the rat. Neuroscience. 2001; 102(1):185-92.
        View in: PubMed
      164. Dina OA, Barletta J, Chen X, Mutero A, Martin A, Messing RO, Levine JD. Key role for the epsilon isoform of protein kinase C in painful alcoholic neuropathy in the rat. J Neurosci. 2000 Nov 15; 20(22):8614-9.
        View in: PubMed
      165. Miao FJ, Janig W, Levine JD. Nociceptive neuroendocrine negative feedback control of neurogenic inflammation activated by capsaicin in the rat paw: role of the adrenal medulla. J Physiol. 2000 Sep 15; 527 Pt 3:601-10.
        View in: PubMed
      166. Topp KS, Tanner KD, Levine JD. Damage to the cytoskeleton of large diameter sensory neurons and myelinated axons in vincristine-induced painful peripheral neuropathy in the rat. J Comp Neurol. 2000 Sep 4; 424(4):563-76.
        View in: PubMed
      167. Schumacher MA, Jong BE, Frey SL, Sudanagunta SP, Capra NF, Levine JD. The stretch-inactivated channel, a vanilloid receptor variant, is expressed in small-diameter sensory neurons in the rat. Neurosci Lett. 2000 Jun 30; 287(3):215-8.
        View in: PubMed
      168. Aley KO, Messing RO, Mochly-Rosen D, Levine JD. Chronic hypersensitivity for inflammatory nociceptor sensitization mediated by the epsilon isozyme of protein kinase C. J Neurosci. 2000 Jun 15; 20(12):4680-5.
        View in: PubMed
      169. Reichling DB, Levine JD. In hot pursuit of the elusive heat transducers. Neuron. 2000 Jun; 26(3):555-8.
        View in: PubMed
      170. Schumacher MA, Moff I, Sudanagunta SP, Levine JD. Molecular cloning of an N-terminal splice variant of the capsaicin receptor. Loss of N-terminal domain suggests functional divergence among capsaicin receptor subtypes. J Biol Chem. 2000 Jan 28; 275(4):2756-62.
        View in: PubMed
      171. Jänig W, Khasar SG, Levine JD, Miao FJ. The role of vagal visceral afferents in the control of nociception. Prog Brain Res. 2000; 122:273-87.
        View in: PubMed
      172. Lo EJ, Green PG, Miao FJ, Relchling DB, Levine JD. Bradykinin-induced neurogenic migration of neutrophils into the rat knee joint. Neuroreport. 1999 Dec 16; 10(18):3821-4.
        View in: PubMed
      173. Strausbaugh HJ, Dallman MF, Levine JD. Repeated, but not acute, stress suppresses inflammatory plasma extravasation. Proc Natl Acad Sci U S A. 1999 Dec 7; 96(25):14629-34.
        View in: PubMed
      174. Miao FJ, Levine JD. Neural and endocrine mechanisms mediating noxious stimulus-induced inhibition of bradykinin plasma extravasation in the rat. J Pharmacol Exp Ther. 1999 Dec; 291(3):1028-37.
        View in: PubMed
      175. Gotter AL, Levine JD, Reppert SM. Sex-linked period genes in the silkmoth, Antheraea pernyi: implications for circadian clock regulation and the evolution of sex chromosomes. Neuron. 1999 Dec; 24(4):953-65.
        View in: PubMed
      176. Gear RW, Miaskowski C, Gordon NC, Paul SM, Heller PH, Levine JD. The kappa opioid nalbuphine produces gender- and dose-dependent analgesia and antianalgesia in patients with postoperative pain. Pain. 1999 Nov; 83(2):339-45.
        View in: PubMed
      177. McCarter GC, Reichling DB, Levine JD. Mechanical transduction by rat dorsal root ganglion neurons in vitro. Neurosci Lett. 1999 Oct 8; 273(3):179-82.
        View in: PubMed
      178. Strausbaugh HJ, Green PG, Lo E, Tangemann K, Reichling DB, Rosen SD, Levine JD. Painful stimulation suppresses joint inflammation by inducing shedding of L-selectin from neutrophils. Nat Med. 1999 Sep; 5(9):1057-61.
        View in: PubMed
      179. Khasar SG, Lin YH, Martin A, Dadgar J, McMahon T, Wang D, Hundle B, Aley KO, Isenberg W, McCarter G, Green PG, Hodge CW, Levine JD, Messing RO. A novel nociceptor signaling pathway revealed in protein kinase C epsilon mutant mice. Neuron. 1999 Sep; 24(1):253-60.
        View in: PubMed
      180. Gear RW, Aley KO, Levine JD. Pain-induced analgesia mediated by mesolimbic reward circuits. J Neurosci. 1999 Aug 15; 19(16):7175-81.
        View in: PubMed
      181. Reichling DB, Levine JD. The primary afferent nociceptor as pattern generator. Pain. 1999 Aug; Suppl 6:S103-9.
        View in: PubMed
      182. Baron R, Levine JD, Fields HL. Causalgia and reflex sympathetic dystrophy: does the sympathetic nervous system contribute to the generation of pain? Muscle Nerve. 1999 Jun; 22(6):678-95.
        View in: PubMed
      183. Chen X, Tanner K, Levine JD. Mechanical sensitization of cutaneous C-fiber nociceptors by prostaglandin E2 in the rat. Neurosci Lett. 1999 May 28; 267(2):105-8.
        View in: PubMed
      184. Green PG, Dahlqvist SR, Isenberg WM, Strausbaugh HJ, Miao FJ, Levine JD. Sex steroid regulation of the inflammatory response: sympathoadrenal dependence in the female rat. J Neurosci. 1999 May 15; 19(10):4082-9.
        View in: PubMed
      185. Baron R, Wasner G, Borgstedt R, Hastedt E, Schulte H, Binder A, Kopper F, Rowbotham M, Levine JD, Fields HL. Effect of sympathetic activity on capsaicin-evoked pain, hyperalgesia, and vasodilatation. Neurology. 1999 Mar 23; 52(5):923-32.
        View in: PubMed
      186. Aley KO, Levine JD. Role of protein kinase A in the maintenance of inflammatory pain. J Neurosci. 1999 Mar 15; 19(6):2181-6.
        View in: PubMed
      187. Khasar SG, McCarter G, Levine JD. Epinephrine produces a beta-adrenergic receptor-mediated mechanical hyperalgesia and in vitro sensitization of rat nociceptors. J Neurophysiol. 1999 Mar; 81(3):1104-12.
        View in: PubMed
      188. Chen X, Levine JD. NOS inhibitor antagonism of PGE2-induced mechanical sensitization of cutaneous C-fiber nociceptors in the rat. J Neurophysiol. 1999 Mar; 81(3):963-6.
        View in: PubMed
      189. Gold MS, Levine JD, Correa AM. Modulation of TTX-R INa by PKC and PKA and their role in PGE2-induced sensitization of rat sensory neurons in vitro. J Neurosci. 1998 Dec 15; 18(24):10345-55.
        View in: PubMed
      190. Green PG, Strausbaugh HJ, Levine JD. Annexin I is a local mediator in neural-endocrine feedback control of inflammation. J Neurophysiol. 1998 Dec; 80(6):3120-6.
        View in: PubMed
      191. Zylka MJ, Shearman LP, Levine JD, Jin X, Weaver DR, Reppert SM. Molecular analysis of mammalian timeless. Neuron. 1998 Nov; 21(5):1115-22.
        View in: PubMed
      192. Khasar SG, Gold MS, Levine JD. A tetrodotoxin-resistant sodium current mediates inflammatory pain in the rat. Neurosci Lett. 1998 Oct 30; 256(1):17-20.
        View in: PubMed
      193. Aley KO, McCarter G, Levine JD. Nitric oxide signaling in pain and nociceptor sensitization in the rat. J Neurosci. 1998 Sep 1; 18(17):7008-14.
        View in: PubMed
      194. Tanner KD, Reichling DB, Levine JD. Nociceptor hyper-responsiveness during vincristine-induced painful peripheral neuropathy in the rat. J Neurosci. 1998 Aug 15; 18(16):6480-91.
        View in: PubMed
      195. Tanner KD, Levine JD, Topp KS. Microtubule disorientation and axonal swelling in unmyelinated sensory axons during vincristine-induced painful neuropathy in rat. J Comp Neurol. 1998 Jun 15; 395(4):481-92.
        View in: PubMed
      196. Gold MS, Reichling DB, Hampl KF, Drasner K, Levine JD. Lidocaine toxicity in primary afferent neurons from the rat. J Pharmacol Exp Ther. 1998 May; 285(2):413-21.
        View in: PubMed
      197. Green PG, Miao FJ, Strausbaugh H, Heller P, Janig W, Levine JD. Endocrine and vagal controls of sympathetically dependent neurogenic inflammation. Ann N Y Acad Sci. 1998 May 1; 840:282-8.
        View in: PubMed
      198. Khasar SG, Miao FJ, Jänig W, Levine JD. Vagotomy-induced enhancement of mechanical hyperalgesia in the rat is sympathoadrenal-mediated. J Neurosci. 1998 Apr 15; 18(8):3043-9.
        View in: PubMed
      199. Levine JD. New directions in pain research: molecules to maladies. Neuron. 1998 Apr; 20(4):649-54.
        View in: PubMed
      200. Khasar SG, Miao JP, Jänig W, Levine JD. Modulation of bradykinin-induced mechanical hyperalgesia in the rat by activity in abdominal vagal afferents. Eur J Neurosci. 1998 Feb; 10(2):435-44.
        View in: PubMed
      201. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature. 1997 Oct 23; 389(6653):816-24.
        View in: PubMed
      202. Aley KO, Levine JD. Different mechanisms mediate development and expression of tolerance and dependence for peripheral mu-opioid antinociception in rat. J Neurosci. 1997 Oct 15; 17(20):8018-23.
        View in: PubMed
      203. Miao FJ, Jänig W, Green PG, Levine JD. Inhibition of bradykinin-induced plasma extravasation produced by noxious cutaneous and visceral stimuli and its modulation by vagal activity. J Neurophysiol. 1997 Sep; 78(3):1285-92.
        View in: PubMed
      204. Reichling DB, Levine JD. Heat transduction in rat sensory neurons by calcium-dependent activation of a cation channel. Proc Natl Acad Sci U S A. 1997 Jun 24; 94(13):7006-11.
        View in: PubMed
      205. Aley KO, Levine JD. Dissociation of tolerance and dependence for opioid peripheral antinociception in rats. J Neurosci. 1997 May 15; 17(10):3907-12.
        View in: PubMed
      206. Green PG, Jänig W, Levine JD. Negative feedback neuroendocrine control of inflammatory response in the rat is dependent on the sympathetic postganglionic neuron. J Neurosci. 1997 May 1; 17(9):3234-8.
        View in: PubMed
      207. Gear RW, Miaskowski C, Heller PH, Paul SM, Gordon NC, Levine JD. Benzodiazepine mediated antagonism of opioid analgesia. Pain. 1997 May; 71(1):25-9.
        View in: PubMed
      208. Reichling DB, Barratt L, Levine JD. Heat-induced cobalt entry: an assay for heat transduction in cultured rat dorsal root ganglion neurons. Neuroscience. 1997 Mar; 77(2):291-4.
        View in: PubMed
      209. Aley KO, Levine JD. Multiple receptors involved in peripheral alpha 2, mu, and A1 antinociception, tolerance, and withdrawal. J Neurosci. 1997 Jan 15; 17(2):735-44.
        View in: PubMed
      210. Miao FJ, Jänig W, Levine JD. Vagal branches involved in inhibition of bradykinin-induced synovial plasma extravasation by intrathecal nicotine and noxious stimulation in the rat. J Physiol. 1997 Jan 15; 498 ( Pt 2):473-81.
        View in: PubMed
      211. Miao FJ, Benowitz NL, Heller PH, Levine JD. Contribution of adrenal hormones to nicotine-induced inhibition of synovial plasma extravasation in the rat. Br J Pharmacol. 1997 Jan; 120(2):298-304.
        View in: PubMed
      212. Ahlgren SC, Wang JF, Levine JD. C-fiber mechanical stimulus-response functions are different in inflammatory versus neuropathic hyperalgesia in the rat. Neuroscience. 1997 Jan; 76(1):285-90.
        View in: PubMed
      213. Gold MS, Dastmalchi S, Levine JD. Alpha 2-adrenergic receptor subtypes in rat dorsal root and superior cervical ganglion neurons. Pain. 1997 Jan; 69(1-2):179-90.
        View in: PubMed
      214. Miao FJ, Jänig W, Green PG, Levine JD. Inhibition of bradykinin-induced synovial plasma extravasation produced by intrathecal nicotine is mediated by the hypothalamopituitary adrenal axis. J Neurophysiol. 1996 Nov; 76(5):2813-21.
        View in: PubMed
      215. Gear RW, Miaskowski C, Gordon NC, Paul SM, Heller PH, Levine JD. Kappa-opioids produce significantly greater analgesia in women than in men. Nat Med. 1996 Nov; 2(11):1248-50.
        View in: PubMed
      216. Khasar SG, Gold MS, Dastmalchi S, Levine JD. Selective attenuation of mu-opioid receptor-mediated effects in rat sensory neurons by intrathecal administration of antisense oligodeoxynucleotides. Neurosci Lett. 1996 Oct 25; 218(1):17-20.
        View in: PubMed
      217. Gold MS, Levine JD. DAMGO inhibits prostaglandin E2-induced potentiation of a TTX-resistant Na+ current in rat sensory neurons in vitro. Neurosci Lett. 1996 Jul 12; 212(2):83-6.
        View in: PubMed
      218. Aley KO, Reichling DB, Levine JD. Vincristine hyperalgesia in the rat: a model of painful vincristine neuropathy in humans. Neuroscience. 1996 Jul; 73(1):259-65.
        View in: PubMed
      219. Gold MS, Shuster MJ, Levine JD. Characterization of six voltage-gated K+ currents in adult rat sensory neurons. J Neurophysiol. 1996 Jun; 75(6):2629-46.
        View in: PubMed
      220. Miao FJ, Benowitz N, Levine JD. Neural and endocrine circuits mediating inhibition of bradykinin-induced plasma extravasation by subcutaneous and spinal-intrathecal nicotine. J Pharmacol Exp Ther. 1996 Jun; 277(3):1510-6.
        View in: PubMed
      221. Pierce PA, Xie GX, Peroutka SJ, Levine JD. Dual effect of the serotonin agonist, sumatriptan, on peripheral neurogenic inflammation. Reg Anesth. 1996 May-Jun; 21(3):219-25.
        View in: PubMed
      222. Miao FJ, Khasar SG, Green PG, Levine JD. Tachyphylaxis develops to bradykinin-induced plasma extravasation in the rat. Neurosci Lett. 1996 Apr 19; 208(2):143-5.
        View in: PubMed
      223. McCall WD, Tanner KD, Levine JD. Formalin induces biphasic activity in C-fibers in the rat. Neurosci Lett. 1996 Apr 12; 208(1):45-8.
        View in: PubMed
      224. Gogas KR, Cho HJ, Botchkina GI, Levine JD, Basbaum AI. Inhibition of noxious stimulus-evoked pain behaviors and neuronal fos-like immunoreactivity in the spinal cord of the rat by supraspinal morphine. Pain. 1996 Apr; 65(1):9-15.
        View in: PubMed
      225. Aley KO, Kinnman E, Levine JD. Delayed sympathectomy after a prolonged hyperalgesia results in a subsequent enhanced acute hyperalgesic response. Neuroscience. 1996 Apr; 71(4):1083-90.
        View in: PubMed
      226. Wang JF, Khasar SG, Ahlgren SC, Levine JD. Sensitization of C-fibres by prostaglandin E2 in the rat is inhibited by guanosine 5'-O-(2-thiodiphosphate), 2',5'-dideoxyadenosine and Walsh inhibitor peptide. Neuroscience. 1996 Mar; 71(1):259-63.
        View in: PubMed
      227. Gold MS, Shuster MJ, Levine JD. Role of a Ca(2+)-dependent slow afterhyperpolarization in prostaglandin E2-induced sensitization of cultured rat sensory neurons. Neurosci Lett. 1996 Mar 1; 205(3):161-4.
        View in: PubMed
      228. Miao FJ, Green PG, Coderre TJ, Jänig W, Levine JD. Sympathetic-dependence in bradykinin-induced synovial plasma extravasation is dose-related. Neurosci Lett. 1996 Mar 1; 205(3):165-8.
        View in: PubMed
      229. Gold MS, Dastmalchi S, Levine JD. Co-expression of nociceptor properties in dorsal root ganglion neurons from the adult rat in vitro. Neuroscience. 1996 Mar; 71(1):265-75.
        View in: PubMed
      230. Gear RW, Gordon NC, Heller PH, Paul S, Miaskowski C, Levine JD. Gender difference in analgesic response to the kappa-opioid pentazocine. Neurosci Lett. 1996 Mar 1; 205(3):207-9.
        View in: PubMed
      231. Khasar SG, Levine JD. Neonatal capsaicin attenuates mechanical nociception in the rat. Neurosci Lett. 1996 Feb 23; 205(2):141-3.
        View in: PubMed
      232. Gold MS, Reichling DB, Shuster MJ, Levine JD. Hyperalgesic agents increase a tetrodotoxin-resistant Na+ current in nociceptors. Proc Natl Acad Sci U S A. 1996 Feb 6; 93(3):1108-12.
        View in: PubMed
      233. Gogas KR, Levine JD, Basbaum AI. Differential contribution of descending controls to the antinociceptive actions of kappa and mu opioids: an analysis of formalin-evoked C-fos expression. J Pharmacol Exp Ther. 1996 Feb; 276(2):801-9.
        View in: PubMed
      234. Miao FJ, Jänig W, Levine Jd. Role of sympathetic postganglionic neurons in synovial plasma extravasation induced by bradykinin. J Neurophysiol. 1996 Feb; 75(2):715-24.
        View in: PubMed
      235. Jänig W, Levine JD, Michaelis M. Interactions of sympathetic and primary afferent neurons following nerve injury and tissue trauma. Prog Brain Res. 1996; 113:161-84.
        View in: PubMed
      236. Pierce PA, Xie GX, Levine JD, Peroutka SJ. 5-Hydroxytryptamine receptor subtype messenger RNAs in rat peripheral sensory and sympathetic ganglia: a polymerase chain reaction study. Neuroscience. 1996 Jan; 70(2):553-9.
        View in: PubMed
      237. Miao FJ, Kinnman E, Jänig W, Levine JD. Variation in the anatomy of the lumbar sympathetic chain in the rat. J Auton Nerv Syst. 1995 Dec 5; 56(1-2):115-8.
        View in: PubMed
      238. Aley KO, Green PG, Levine JD. Opioid and adenosine peripheral antinociception are subject to tolerance and withdrawal. J Neurosci. 1995 Dec; 15(12):8031-8.
        View in: PubMed
      239. Gordon NC, Gear RW, Heller PH, Paul S, Miaskowski C, Levine JD. Enhancement of morphine analgesia by the GABAB agonist baclofen. Neuroscience. 1995 Nov; 69(2):345-9.
        View in: PubMed
      240. Khasar SG, Miao FJ, Levine JD. Inflammation modulates the contribution of receptor-subtypes to bradykinin-induced hyperalgesia in the rat. Neuroscience. 1995 Nov; 69(2):685-90.
        View in: PubMed
      241. Pierce PA, Xie GX, Peroutka SJ, Green PG, Levine JD. 5-Hydroxytryptamine-induced synovial plasma extravasation is mediated via 5-hydroxytryptamine2A receptors on sympathetic efferent terminals. J Pharmacol Exp Ther. 1995 Oct; 275(1):502-8.
        View in: PubMed
      242. Matos FF, Rollema H, Taiwo YO, Levine JD, Basbaum AI. Relationship between analgesia and extracellular morphine in brain and spinal cord in awake rats. Brain Res. 1995 Sep 25; 693(1-2):187-95.
        View in: PubMed
      243. Pierce PA, King BS, Rampil IJ, Levine JD. Halothane selectively inhibits bradykinin-induced synovial plasma extravasation. Anesthesiology. 1995 Sep; 83(3):568-73.
        View in: PubMed
      244. Khasar SG, Wang JF, Taiwo YO, Heller PH, Green PG, Levine JD. Mu-opioid agonist enhancement of prostaglandin-induced hyperalgesia in the rat: a G-protein beta gamma subunit-mediated effect? Neuroscience. 1995 Jul; 67(1):189-95.
        View in: PubMed
      245. Green PG, Miao FJ, Jänig W, Levine JD. Negative feedback neuroendocrine control of the inflammatory response in rats. J Neurosci. 1995 Jun; 15(6):4678-86.
        View in: PubMed
      246. Gear RW, Gordon NC, Heller PH, Levine JD. Enhancement of morphine analgesia by the alpha 2-adrenergic antagonist yohimbine. Neuroscience. 1995 May; 66(1):5-8.
        View in: PubMed
      247. Khasar SG, Green PG, Chou B, Levine JD. Peripheral nociceptive effects of alpha 2-adrenergic receptor agonists in the rat. Neuroscience. 1995 May; 66(2):427-32.
        View in: PubMed
      248. Sutters KA, Levine JD, Dibble S, Savedra M, Miaskowski C. Analgesic efficacy and safety of single-dose intramuscular ketorolac for postoperative pain management in children following tonsillectomy. Pain. 1995 Apr; 61(1):145-53.
        View in: PubMed
      249. Gear RW, Levine JD. Antinociception produced by an ascending spino-supraspinal pathway. J Neurosci. 1995 Apr; 15(4):3154-61.
        View in: PubMed
      250. Kinnman E, Levine JD. Involvement of the sympathetic postganglionic neuron in capsaicin-induced secondary hyperalgesia in the rat. Neuroscience. 1995 Mar; 65(1):283-91.
        View in: PubMed
      251. Ouseph AK, Khasar SG, Levine JD. Multiple second messenger systems act sequentially to mediate rolipram-induced prolongation of prostaglandin E2-induced mechanical hyperalgesia in the rat. Neuroscience. 1995 Feb; 64(3):769-76.
        View in: PubMed
      252. Khasar SG, Ouseph AK, Chou B, Ho T, Green PG, Levine JD. Is there more than one prostaglandin E receptor subtype mediating hyperalgesia in the rat hindpaw? Neuroscience. 1995 Feb; 64(4):1161-5.
        View in: PubMed
      253. Kinnman E, Levine JD. Sensory and sympathetic contributions to nerve injury-induced sensory abnormalities in the rat. Neuroscience. 1995 Feb; 64(3):751-67.
        View in: PubMed
      254. Ouseph AK, Levine JD. Alpha 1-adrenoceptor-mediated sympathetically dependent mechanical hyperalgesia in the rat. Eur J Pharmacol. 1995 Jan 24; 273(1-2):107-12.
        View in: PubMed
      255. Jasmin L, Wang H, Tarczy-Hornoch K, Levine JD, Basbaum AI. Differential effects of morphine on noxious stimulus-evoked fos-like immunoreactivity in subpopulations of spinoparabrachial neurons. J Neurosci. 1994 Dec; 14(12):7252-60.
        View in: PubMed
      256. Levine JD, Casey CI, Kalderon DD, Jackson FR. Altered circadian pacemaker functions and cyclic AMP rhythms in the Drosophila learning mutant dunce. Neuron. 1994 Oct; 13(4):967-74.
        View in: PubMed
      257. Khasar SG, Ho T, Green PG, Levine JD. Comparison of prostaglandin E1- and prostaglandin E2-induced hyperalgesia in the rat. Neuroscience. 1994 Sep; 62(2):345-50.
        View in: PubMed
      258. Miao FJ, Jänig W, Dallman MF, Benowitz NL, Heller PH, Basbaum AI, Levine JD. Role of vagal afferents and spinal pathways modulating inhibition of bradykinin-induced plasma extravasation by intrathecal nicotine. J Neurophysiol. 1994 Sep; 72(3):1199-207.
        View in: PubMed
      259. Ahlgren SC, Levine JD. Protein kinase C inhibitors decrease hyperalgesia and C-fiber hyperexcitability in the streptozotocin-diabetic rat. J Neurophysiol. 1994 Aug; 72(2):684-92.
        View in: PubMed
      260. Gold MS, White DM, Ahlgren SC, Guo M, Levine JD. Catecholamine-induced mechanical sensitization of cutaneous nociceptors in the rat. Neurosci Lett. 1994 Jul 4; 175(1-2):166-70.
        View in: PubMed
      261. Gordon NC, Heller PH, Gear RW, Levine JD. Interactions between fluoxetine and opiate analgesia for postoperative dental pain. Pain. 1994 Jul; 58(1):85-8.
        View in: PubMed
      262. Levine JD, Zhao XS, Miselis RR. Direct and indirect retinohypothalamic projections to the supraoptic nucleus in the female albino rat. J Comp Neurol. 1994 Mar 8; 341(2):214-24.
        View in: PubMed
      263. Green PG, Luo J, Heller PH, Levine JD. Effect of E-type prostaglandins on bradykinin-induced plasma extravasation in the knee joint of the rat. Eur J Pharmacol. 1994 Feb 3; 252(2):127-32.
        View in: PubMed
      264. Jasmin L, Gogas KR, Ahlgren SC, Levine JD, Basbaum AI. Walking evokes a distinctive pattern of Fos-like immunoreactivity in the caudal brainstem and spinal cord of the rat. Neuroscience. 1994 Jan; 58(2):275-86.
        View in: PubMed
      265. Jasmin L, Tarczy-Hornoch K, Wang H, Levine JD, Basbaum AI. Transneuronal spread of the pseudorabies virus after injection into the central nucleus of the amygdala in the rat. Gene Ther. 1994; 1 Suppl 1:S74.
        View in: PubMed
      266. Miaskowski C, Levine JD. Reply to the letter by J.L. Plummer. Pain. 1993 Dec; 55(3):401.
        View in: PubMed
      267. Miaskowski C, Franck LS, Putris J, Levine JD. Temporal dissociation of recovery from antinociceptive and motor effects following intrathecal administration of a selective mu-opioid agonist. Nurs Res. 1993 Nov-Dec; 42(6):344-8.
        View in: PubMed
      268. Green PG, Luo J, Hammond ER, Levine JD. Trypsin enhances sympathetic neuron-dependent plasma extravasation in the rat knee joint. Neurosci Lett. 1993 Aug 6; 158(1):117-9.
        View in: PubMed
      269. Perry F, Heller PH, Levine JD. The 'significance' of statistical significance. Pain. 1993 Aug; 54(2):231.
        View in: PubMed
      270. Green PG, Luo J, Heller PH, Levine JD. Further substantiation of a significant role for the sympathetic nervous system in inflammation. Neuroscience. 1993 Aug; 55(4):1037-43.
        View in: PubMed
      271. Chi SI, Levine JD, Basbaum AI. Effects of injury discharge on the persistent expression of spinal cord fos-like immunoreactivity produced by sciatic nerve transection in the rat. Brain Res. 1993 Jul 23; 617(2):220-4.
        View in: PubMed
      272. Chi SI, Levine JD, Basbaum AI. Peripheral and central contributions to the persistent expression of spinal cord fos-like immunoreactivity produced by sciatic nerve transection in the rat. Brain Res. 1993 Jul 23; 617(2):225-37.
        View in: PubMed
      273. Ahlgren SC, Levine JD. Mechanical hyperalgesia in streptozotocin-diabetic rats is not sympathetically maintained. Brain Res. 1993 Jul 9; 616(1-2):171-5.
        View in: PubMed
      274. Levine JD, Fields HL, Basbaum AI. Peptides and the primary afferent nociceptor. J Neurosci. 1993 Jun; 13(6):2273-86.
        View in: PubMed
      275. Gordon NC, Heller PH, Gear RW, Levine JD. Temporal factors in the enhancement of morphine analgesia by desipramine. Pain. 1993 Jun; 53(3):273-6.
        View in: PubMed
      276. Khasar SG, Green PG, Levine JD. Comparison of intradermal and subcutaneous hyperalgesic effects of inflammatory mediators in the rat. Neurosci Lett. 1993 Apr 30; 153(2):215-8.
        View in: PubMed
      277. Miaskowski C, Taiwo YO, Levine JD. Antinociception produced by receptor selective opioids. Modulation of supraspinal antinociceptive effects by spinal opioids. Brain Res. 1993 Apr 9; 608(1):87-94.
        View in: PubMed
      278. Miao FJ, Dallman MF, Benowitz NL, Basbaum AI, Levine JD. Adrenal medullary modulation of the inhibition of bradykinin-induced plasma extravasation by intrathecal nicotine. J Pharmacol Exp Ther. 1993 Feb; 264(2):839-44.
        View in: PubMed
      279. Ahlgren SC, Levine JD. Mechanical hyperalgesia in streptozotocin-diabetic rats. Neuroscience. 1993 Feb; 52(4):1049-55.
        View in: PubMed
      280. Green PG, Luo J, Heller PH, Levine JD. Neurogenic and non-neurogenic mechanisms of plasma extravasation in the rat. Neuroscience. 1993 Feb; 52(3):735-43.
        View in: PubMed
      281. Gogas KR, Levine JD, Basbaum AI. Mechanisms of opioid-mediated antinociception: correlation of Fos expression and behavior. NIDA Res Monogr. 1993; 125:134-60.
        View in: PubMed
      282. Green PG, Luo J, Heller P, Levine JD. Modulation of bradykinin-induced plasma extravasation in the rat knee joint by sympathetic co-transmitters. Neuroscience. 1993 Jan; 52(2):451-8.
        View in: PubMed
      283. Ahlgren SC, White DM, Levine JD. Increased responsiveness of sensory neurons in the saphenous nerve of the streptozotocin-diabetic rat. J Neurophysiol. 1992 Dec; 68(6):2077-85.
        View in: PubMed
      284. Miao FJ, Helms C, Benowitz NL, Basbaum AI, Heller PH, Levine JD. Chronically administered nicotine attenuates bradykinin-induced plasma extravasation and aggravates arthritis-induced joint injury in the rat. Neuroscience. 1992 Dec; 51(3):649-55.
        View in: PubMed
      285. Miaskowski C, Levine JD. Inhibition of spinal opioid analgesia by supraspinal administration of selective opioid antagonists. Brain Res. 1992 Nov 20; 596(1-2):41-5.
        View in: PubMed
      286. Miaskowski C, Levine JD. Antinociception produced by receptor selective opioids: modulation of spinal antinociceptive effects by supraspinal opioids. Brain Res. 1992 Nov 6; 595(1):32-8.
        View in: PubMed
      287. Green PG, Basbaum AI, Levine JD. Sensory neuropeptide interactions in the production of plasma extravasation in the rat. Neuroscience. 1992 Oct; 50(3):745-9.
        View in: PubMed
      288. Miao FJ, Benowitz NL, Basbaum AI, Levine JD. Sympathoadrenal contribution to nicotinic and muscarinic modulation of bradykinin-induced plasma extravasation in the knee joint of the rat. J Pharmacol Exp Ther. 1992 Sep; 262(3):889-95.
        View in: PubMed
      289. Green PG, Levine JD. Delta- and kappa-opioid agonists inhibit plasma extravasation induced by bradykinin in the knee joint of the rat. Neuroscience. 1992 Jul; 49(1):129-33.
        View in: PubMed
      290. Sherbourne CD, Gonzales R, Goldyne ME, Levine JD. Norepinephrine-induced increase in sympathetic neuron-derived prostaglandins is independent of neuronal release mechanisms. Neurosci Lett. 1992 May 25; 139(2):188-90.
        View in: PubMed
      291. Miaskowski C, Sutters KA, Taiwo YO, Levine JD. Antinociceptive and motor effects of delta/mu and kappa/mu combinations of intrathecal opioid agonists. Pain. 1992 Apr; 49(1):137-44.
        View in: PubMed
      292. Gordon NC, Heller PH, Levine JD. Enhancement of pentazocine analgesia by clonidine. Pain. 1992 Feb; 48(2):167-9.
        View in: PubMed
      293. Taiwo YO, Levine JD. Serotonin is a directly-acting hyperalgesic agent in the rat. Neuroscience. 1992; 48(2):485-90.
        View in: PubMed
      294. Taiwo YO, Heller PH, Levine JD. Mediation of serotonin hyperalgesia by the cAMP second messenger system. Neuroscience. 1992; 48(2):479-83.
        View in: PubMed
      295. Devor M, White DM, Goetzl EJ, Levine JD. Eicosanoids, but not tachykinins, excite C-fiber endings in rat sciatic nerve-end neuromas. Neuroreport. 1992 Jan; 3(1):21-4.
        View in: PubMed
      296. Miaskowski C, Taiwo YO, Levine JD. Contribution of supraspinal mu- and delta-opioid receptors to antinociception in the rat. Eur J Pharmacol. 1991 Dec 3; 205(3):247-52.
        View in: PubMed
      297. Franck LS, Miaskowski C, Putris J, Levine JD. Dissociation of antinociceptive and motor effects of supraspinal opioid agonists in the rat. Brain Res. 1991 Nov 1; 563(1-2):123-6.
        View in: PubMed
      298. Pitchford S, Levine JD. Prostaglandins sensitize nociceptors in cell culture. Neurosci Lett. 1991 Oct 28; 132(1):105-8.
        View in: PubMed
      299. Basbaum AI, Levine JD. Opiate analgesia. How central is a peripheral target? N Engl J Med. 1991 Oct 17; 325(16):1168-9.
        View in: PubMed
      300. Gonzales R, Sherbourne CD, Goldyne ME, Levine JD. Noradrenaline-induced prostaglandin production by sympathetic postganglionic neurons is mediated by alpha 2-adrenergic receptors. J Neurochem. 1991 Oct; 57(4):1145-50.
        View in: PubMed
      301. Gordon NC, Heller PH, Levine JD. Lack of effect of ephedrine on opiate analgesia. Pain. 1991 Oct; 47(1):21-3.
        View in: PubMed
      302. White DM, Taiwo YO, Coderre TJ, Levine JD. Delayed activation of nociceptors: correlation with delayed pain sensations induced by sustained stimuli. J Neurophysiol. 1991 Sep; 66(3):729-34.
        View in: PubMed
      303. Lee A, Coderre TJ, Basbaum AI, Levine JD. Sympathetic neuron factors involved in bradykinin-induced plasma extravasation in the rat. Brain Res. 1991 Aug 23; 557(1-2):146-8.
        View in: PubMed
      304. Perry F, Heller PH, Levine JD. A possible indicator of functional pain: poor pain scale correlation. Pain. 1991 Aug; 46(2):191-3.
        View in: PubMed
      305. White DM, Levine JD. Different mechanical transduction mechanisms for the immediate and delayed responses of rat C-fiber nociceptors. J Neurophysiol. 1991 Aug; 66(2):363-8.
        View in: PubMed
      306. Miaskowski C, Sutters KA, Taiwo YO, Levine JD. Comparison of the antinociceptive and motor effects of intrathecal opioid agonists in the rat. Brain Res. 1991 Jul 5; 553(1):105-9.
        View in: PubMed
      307. Taiwo YO, Levine JD, Burch RM, Woo JE, Mobley WC. Hyperalgesia induced in the rat by the amino-terminal octapeptide of nerve growth factor. Proc Natl Acad Sci U S A. 1991 Jun 15; 88(12):5144-8.
        View in: PubMed
      308. Gonzales R, Coderre TJ, Sherbourne CD, Levine JD. Postnatal development of neurogenic inflammation in the rat. Neurosci Lett. 1991 Jun 10; 127(1):25-7.
        View in: PubMed
      309. Green PG, Basbaum AI, Helms C, Levine JD. Purinergic regulation of bradykinin-induced plasma extravasation and adjuvant-induced arthritis in the rat. Proc Natl Acad Sci U S A. 1991 May 15; 88(10):4162-5.
        View in: PubMed
      310. Basbaum AI, Levine JD. The contribution of the nervous system to inflammation and inflammatory disease. Can J Physiol Pharmacol. 1991 May; 69(5):647-51.
        View in: PubMed
      311. Levine JD, Weiss ML, Rosenwasser AM, Miselis RR. Retinohypothalamic tract in the female albino rat: a study using horseradish peroxidase conjugated to cholera toxin. J Comp Neurol. 1991 Apr 8; 306(2):344-60.
        View in: PubMed
      312. Taiwo YO, Levine JD. Kappa- and delta-opioids block sympathetically dependent hyperalgesia. J Neurosci. 1991 Apr; 11(4):928-32.
        View in: PubMed
      313. Coderre TJ, Basbaum AI, Helms C, Levine JD. High-dose epinephrine acts at alpha 2-adrenoceptors to suppress experimental arthritis. Brain Res. 1991 Mar 29; 544(2):325-8.
        View in: PubMed
      314. Taiwo YO, Levine JD. Further confirmation of the role of adenyl cyclase and of cAMP-dependent protein kinase in primary afferent hyperalgesia. Neuroscience. 1991; 44(1):131-5.
        View in: PubMed
      315. Gogas KR, Presley RW, Levine JD, Basbaum AI. The antinociceptive action of supraspinal opioids results from an increase in descending inhibitory control: correlation of nociceptive behavior and c-fos expression. Neuroscience. 1991; 42(3):617-28.
        View in: PubMed
      316. Faucett JA, Levine JD. The contributions of interpersonal conflict to chronic pain in the presence or absence of organic pathology. Pain. 1991 Jan; 44(1):35-43.
        View in: PubMed
      317. Coderre TJ, Chan AK, Helms C, Basbaum AI, Levine JD. Increasing sympathetic nerve terminal-dependent plasma extravasation correlates with decreased arthritic joint injury in rats. Neuroscience. 1991; 40(1):185-9.
        View in: PubMed
      318. Bjerknes L, Coderre TJ, Green PG, Basbaum AI, Levine JD. Neutrophils contribute to sympathetic nerve terminal-dependent plasma extravasation in the knee joint of the rat. Neuroscience. 1991; 43(2-3):679-85.
        View in: PubMed
      319. Yanovski JA, Rosenwasser AM, Levine JD, Adler NT. The circadian activity rhythms of rats with mid- and parasagittal 'split-SCN' knife cuts and pinealectomy. Brain Res. 1990 Dec 24; 537(1-2):216-26.
        View in: PubMed
      320. Taiwo YO, Levine JD. Effects of cyclooxygenase products of arachidonic acid metabolism on cutaneous nociceptive threshold in the rat. Brain Res. 1990 Dec 24; 537(1-2):372-4.
        View in: PubMed
      321. Levine JD, Coderre TJ, White DM, Finkbeiner WE, Basbaum AI. Denervation-induced inflammation in the rat. Neurosci Lett. 1990 Oct 30; 119(1):37-40.
        View in: PubMed
      322. Sutters KA, Miaskowski C, Taiwo YO, Levine JD. Analgesic synergy and improved motor function produced by combinations of mu-delta- and mu-kappa-opioids. Brain Res. 1990 Oct 22; 530(2):290-4.
        View in: PubMed
      323. Coderre TJ, Gonzales R, Goldyne ME, West J, Levine JD. Noxious stimulus-induced increase in spinal prostaglandin E2 is noradrenergic terminal-dependent. Neurosci Lett. 1990 Jul 31; 115(2-3):253-8.
        View in: PubMed
      324. Levine JD, Coderre TJ, Covinsky K, Basbaum AI. Neural influences on synovial mast cell density in rat. J Neurosci Res. 1990 Jul; 26(3):301-7.
        View in: PubMed
      325. Miaskowski C, Taiwo YO, Levine JD. Intracerebroventricular naloxone produces a dose-dependent, monotonic increase in nociceptive threshold in the rat. Brain Res. 1990 May 7; 515(1-2):323-5.
        View in: PubMed
      326. White DM, Basbaum AI, Goetzl EJ, Levine JD. The 15-lipoxygenase product, 8R,15S-diHETE, stereospecifically sensitizes C-fiber mechanoheat nociceptors in hairy skin of rat. J Neurophysiol. 1990 May; 63(5):966-70.
        View in: PubMed
      327. Levine JD, Basbaum AI. Neurogenic mechanism for symmetrical arthritis. Lancet. 1990 Mar 31; 335(8692):795.
        View in: PubMed
      328. Levine JD, Taiwo YO. Hyperalgesic pain: a review. Anesth Prog. 1990 Mar-Jun; 37(2-3):133-5.
        View in: PubMed
      329. Miaskowski C, Taiwo YO, Levine JD. Kappa- and delta-opioid agonists synergize to produce potent analgesia. Brain Res. 1990 Feb 12; 509(1):165-8.
        View in: PubMed
      330. Taiwo YO, Levine JD. Direct cutaneous hyperalgesia induced by adenosine. Neuroscience. 1990; 38(3):757-62.
        View in: PubMed
      331. Taiwo YO, Heller PH, Levine JD. Characterization of distinct phospholipases mediating bradykinin and noradrenaline hyperalgesia. Neuroscience. 1990; 39(2):523-31.
        View in: PubMed
      332. Heller PH, Perry F, Jewett DL, Levine JD. Autonomic components of the human pupillary light reflex. Invest Ophthalmol Vis Sci. 1990 Jan; 31(1):156-62.
        View in: PubMed
      333. Presley RW, Menétrey D, Levine JD, Basbaum AI. Systemic morphine suppresses noxious stimulus-evoked Fos protein-like immunoreactivity in the rat spinal cord. J Neurosci. 1990 Jan; 10(1):323-35.
        View in: PubMed
      334. Coderre TJ, Basbaum AI, Dallman MF, Helms C, Levine JD. Epinephrine exacerbates arthritis by an action at presynaptic B2-adrenoceptors. Neuroscience. 1990; 34(2):521-3.
        View in: PubMed
      335. Gonzales R, Goldyne ME, Taiwo YO, Levine JD. Production of hyperalgesic prostaglandins by sympathetic postganglionic neurons. J Neurochem. 1989 Nov; 53(5):1595-8.
        View in: PubMed
      336. Perry F, Heller PH, Kamiya J, Levine JD. Altered autonomic function in patients with arthritis or with chronic myofascial pain. Pain. 1989 Oct; 39(1):77-84.
        View in: PubMed
      337. Taiwo YO, Levine JD. Prostaglandin effects after elimination of indirect hyperalgesic mechanisms in the skin of the rat. Brain Res. 1989 Jul 17; 492(1-2):397-9.
        View in: PubMed
      338. Taiwo YO, Levine JD. Contribution of guanine nucleotide regulatory proteins to prostaglandin hyperalgesia in the rat. Brain Res. 1989 Jul 17; 492(1-2):400-3.
        View in: PubMed
      339. Menétrey D, Gannon A, Levine JD, Basbaum AI. Expression of c-fos protein in interneurons and projection neurons of the rat spinal cord in response to noxious somatic, articular, and visceral stimulation. J Comp Neurol. 1989 Jul 8; 285(2):177-95.
        View in: PubMed
      340. Coderre TJ, Basbaum AI, Levine JD. Neural control of vascular permeability: interactions between primary afferents, mast cells, and sympathetic efferents. J Neurophysiol. 1989 Jul; 62(1):48-58.
        View in: PubMed
      341. Landis CA, Robinson CR, Helms C, Levine JD. Differential effects of acetylsalicylic acid and acetaminophen on sleep abnormalities in a rat chronic pain model. Brain Res. 1989 May 29; 488(1-2):195-201.
        View in: PubMed
      342. Levine JD, Taiwo YO. Beta-estradiol induced catecholamine-sensitive hyperalgesia: a contribution to pain in Raynaud's phenomenon. Brain Res. 1989 May 15; 487(1):143-7.
        View in: PubMed
      343. Taiwo YO, Coderre TJ, Levine JD. The contribution of training to sensitivity in the nociceptive paw-withdrawal test. Brain Res. 1989 May 15; 487(1):148-51.
        View in: PubMed
      344. Landis CA, Levine JD, Robinson CR. Decreased slow-wave and paradoxical sleep in a rat chronic pain model. Sleep. 1989 Apr; 12(2):167-77.
        View in: PubMed
      345. Taiwo YO, Basbaum AI, Perry F, Levine JD. Paradoxical analgesia produced by low doses of the opiate-antagonist naloxone is mediated by interaction at a site with characteristics of the delta opioid receptor. J Pharmacol Exp Ther. 1989 Apr; 249(1):97-100.
        View in: PubMed
      346. Taiwo YO, Bjerknes LK, Goetzl EJ, Levine JD. Mediation of primary afferent peripheral hyperalgesia by the cAMP second messenger system. Neuroscience. 1989; 32(3):577-80.
        View in: PubMed
      347. Levine JD, Taiwo YO. Involvement of the mu-opiate receptor in peripheral analgesia. Neuroscience. 1989; 32(3):571-5.
        View in: PubMed
      348. Levine JD, Gordon NC, Taiwo YO, Coderre TJ. Potentiation of pentazocine analgesia by low-dose naloxone. J Clin Invest. 1988 Nov; 82(5):1574-7.
        View in: PubMed
      349. Taiwo YO, Levine JD. Characterization of the arachidonic acid metabolites mediating bradykinin and noradrenaline hyperalgesia. Brain Res. 1988 Aug 23; 458(2):402-6.
        View in: PubMed
      350. Martin HA, Basbaum AI, Goetzl EJ, Levine JD. Leukotriene B4 decreases the mechanical and thermal thresholds of C-fiber nociceptors in the hairy skin of the rat. J Neurophysiol. 1988 Aug; 60(2):438-45.
        View in: PubMed
      351. Perry F, Heller PH, Levine JD. Differing correlations between pain measures in syndromes with or without explicable organic pathology. Pain. 1988 Aug; 34(2):185-9.
        View in: PubMed
      352. Landis CA, Robinson CR, Levine JD. Sleep fragmentation in the arthritic rat. Pain. 1988 Jul; 34(1):93-9.
        View in: PubMed
      353. Levine JD, Coderre TJ, Helms C, Basbaum AI. Beta 2-adrenergic mechanisms in experimental arthritis. Proc Natl Acad Sci U S A. 1988 Jun; 85(12):4553-6.
        View in: PubMed
      354. Levine JD, Gordon NC. Synergism between the analgesic actions of morphine and pentazocine. Pain. 1988 Jun; 33(3):369-72.
        View in: PubMed
      355. Levine JD, Moskowitz MA, Basbaum AI. The effect of gold, an antirheumatic therapy, on substance P levels in rat peripheral nerve. Neurosci Lett. 1988 Apr 22; 87(1-2):200-2.
        View in: PubMed
      356. Taiwo YO, Levine JD. Prostaglandins inhibit endogenous pain control mechanisms by blocking transmission at spinal noradrenergic synapses. J Neurosci. 1988 Apr; 8(4):1346-9.
        View in: PubMed
      357. Goetzl EJ, Burrall BA, Baud L, Scriven KH, Levine JD, Koo CH. Generation and recognition of leukotriene mediators of hypersensitivity and inflammation. Dig Dis Sci. 1988 Mar; 33(3 Suppl):36S-40S.
        View in: PubMed
      358. Taiwo YO, Goetzl EJ, Levine JD. Hyperalgesia onset latency suggests a hierarchy of action. Brain Res. 1987 Oct 13; 423(1-2):333-7.
        View in: PubMed
      359. Levine JD, Goetzl EJ, Basbaum AI. Contribution of the nervous system to the pathophysiology of rheumatoid arthritis and other polyarthritides. Rheum Dis Clin North Am. 1987 Aug; 13(2):369-83.
        View in: PubMed
      360. Martin HA, Basbaum AI, Kwiat GC, Goetzl EJ, Levine JD. Leukotriene and prostaglandin sensitization of cutaneous high-threshold C- and A-delta mechanonociceptors in the hairy skin of rat hindlimbs. Neuroscience. 1987 Aug; 22(2):651-9.
        View in: PubMed
      361. Levine JD, Fye K, Heller P, Basbaum AI, Whiting-O'Keefe Q. Clinical response to regional intravenous guanethidine in patients with rheumatoid arthritis. J Rheumatol. 1986 Dec; 13(6):1040-3.
        View in: PubMed
      362. Levine JD, Dardick SJ, Roizen MF, Helms C, Basbaum AI. Contribution of sensory afferents and sympathetic efferents to joint injury in experimental arthritis. J Neurosci. 1986 Dec; 6(12):3423-9.
        View in: PubMed
      363. Levine JD, Rosenwasser AM, Yanovski JA, Adler NT. Circadian activity rhythms in rats with midbrain raphe lesions. Brain Res. 1986 Oct 8; 384(2):240-9.
        View in: PubMed
      364. Levine JD, Gordon NC, Smith R, McBryde R. Desipramine enhances opiate postoperative analgesia. Pain. 1986 Oct; 27(1):45-9.
        View in: PubMed
      365. Levine JD, Taiwo YO, Collins SD, Tam JK. Noradrenaline hyperalgesia is mediated through interaction with sympathetic postganglionic neurone terminals rather than activation of primary afferent nociceptors. Nature. 1986 Sep 11-17; 323(6084):158-60.
        View in: PubMed
      366. Dardick SJ, Basbaum AI, Levine JD. The contribution of pain to disability in experimentally induced arthritis. Arthritis Rheum. 1986 Aug; 29(8):1017-22.
        View in: PubMed
      367. Levine JD, Goldstine J, Mayes M, Moskowitz MA, Basbaum AI. The neurotoxic effect of gold sodium thiomalate on the peripheral nerves of the rat. Insights into the antiinflammatory actions of gold therapy. Arthritis Rheum. 1986 Jul; 29(7):897-901.
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      368. Levine JD, Lam D, Taiwo YO, Donatoni P, Goetzl EJ. Hyperalgesic properties of 15-lipoxygenase products of arachidonic acid. Proc Natl Acad Sci U S A. 1986 Jul; 83(14):5331-4.
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      369. Taiwo YO, Levine JD. Indomethacin blocks central nociceptive effects of PGF2 alpha. Brain Res. 1986 May 14; 373(1-2):81-4.
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      370. Levine JD, Gordon NC. Method of administration determines the effect of naloxone on pain. Brain Res. 1986 Feb 19; 365(2):377-8.
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      371. Levine JD, Gooding J, Donatoni P, Borden L, Goetzl EJ. The role of the polymorphonuclear leukocyte in hyperalgesia. J Neurosci. 1985 Nov; 5(11):3025-9.
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      372. Levine JD, Moskowitz MA, Basbaum AI. The contribution of neurogenic inflammation in experimental arthritis. J Immunol. 1985 Aug; 135(2 Suppl):843s-847s.
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      373. Levine JD, Collier DH, Basbaum AI, Moskowitz MA, Helms CA. Hypothesis: the nervous system may contribute to the pathophysiology of rheumatoid arthritis. J Rheumatol. 1985 Jun; 12(3):406-11.
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      374. Levine JD, Dardick SJ, Basbaum AI, Scipio E. Reflex neurogenic inflammation. I. Contribution of the peripheral nervous system to spatially remote inflammatory responses that follow injury. J Neurosci. 1985 May; 5(5):1380-6.
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      375. Levine JD, Gordon NC. Influence of the method of drug administration on analgesic response. Nature. 1984 Dec 20-1985 Jan 2; 312(5996):755-6.
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      376. Levine JD, Clark R, Devor M, Helms C, Moskowitz MA, Basbaum AI. Intraneuronal substance P contributes to the severity of experimental arthritis. Science. 1984 Nov 2; 226(4674):547-9.
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      377. Fields HL, Levine JD. Pain--mechanics and management. West J Med. 1984 Sep; 141(3):347-57.
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      378. Levine JD, Lau W, Kwiat G, Goetzl EJ. Leukotriene B4 produces hyperalgesia that is dependent on polymorphonuclear leukocytes. Science. 1984 Aug 17; 225(4663):743-5.
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      379. Levine JD, Feldmesser M, Tecott L, Lane S, Gordon NC. The role of stimulus intensity and stress in opioid-mediated analgesia. Brain Res. 1984 Jun 25; 304(2):265-9.
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      380. Payan DG, Levine JD, Goetzl EJ. Modulation of immunity and hypersensitivity by sensory neuropeptides. J Immunol. 1984 Apr; 132(4):1601-4.
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      381. Levine JD, Feldmesser M, Tecott L, Gordon NC, Izdebski K. Pain-induced vocalization in the rat and its modification by pharmacological agents. Brain Res. 1984 Mar 26; 296(1):121-7.
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      382. Harlan JM, Levine JD, Callahan KS, Schwartz BR, Harker LA. Glutathione redox cycle protects cultured endothelial cells against lysis by extracellularly generated hydrogen peroxide. J Clin Invest. 1984 Mar; 73(3):706-13.
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      383. Naifeh KH, Heller PH, Perry F, Gordon NC, Levine JD. Altered electrodermal responsivity associated with clinical pain. Pain. 1983 Jul; 16(3):277-83.
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      384. Levine JD, Gordon NC. Pain in prelingual children and its evaluation by pain-induced vocalization. Pain. 1982 Oct; 14(2):85-93.
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      385. Levine JD, Gordon NC, Fields HL. Naloxone fails to antagonize nitrous oxide analgesia for clinical pain. Pain. 1982 Jun; 13(2):165-70.
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      386. Levine JD, Lane SR, Gordon NC, Fields HL. A spinal opioid synapse mediates the interaction of spinal and brain stem sites in morphine analgesia. Brain Res. 1982 Mar 18; 236(1):85-91.
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      387. Levine JD, Gordon NC, Smith R, Fields HL. Post-operative pain: effect of extent of injury and attention. Brain Res. 1982 Feb 25; 234(2):500-4.
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      388. Levine JD, Gordon NC, Smith R, Fields HL. Analgesic responses to morphine and placebo in individuals with postoperative pain. Pain. 1981 Jun; 10(3):379-89.
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      389. Gordon NC, Levine JD. Physiological substrates of placebo analgesia. Psychopharmacol Bull. 1981 Apr; 17(2):76-7.
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      390. Fields HL, Levine JD. Biology of placebo analgesia. Am J Med. 1981 Apr; 70(4):745-6.
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      391. Levine JD, Murphy DT, Seidenwurm D, Cortez A, Fields HL. A study of the quantal (all-or-none) change in reflex latency produced by opiate analgesics. Brain Res. 1980 Nov 10; 201(1):129-41.
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      392. Levine JD, Gordon NC, Bornstein JC, Fields HL. Role of pain in placebo analgesia. Proc Natl Acad Sci U S A. 1979 Jul; 76(7):3528-31.
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      393. Levine JD, Gordon NC, Fields HL. Naloxone dose dependently produces analgesia and hyperalgesia in postoperative pain. Nature. 1979 Apr 19; 278(5706):740-1.
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      394. Levine JD, Gordon NC, Fields HL. The mechanism of placebo analgesia. Lancet. 1978 Sep 23; 2(8091):654-7.
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      395. Levine JD, Gordon NC, Jones RT, Fields HL. The narcotic antagonist naloxone enhances clinical pain. Nature. 1978 Apr 27; 272(5656):826-7.
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      396. Levine JD, Gormley J, Fields HL. Observations on the analgesic effects of needle puncture (acupuncture). Pain. 1976 Jun; 2(2):149-59.
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