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Carissa Chu, MD

Photo of Carissa Chu, MD
Title(s)Assistant Professor, Urology
SchoolSchool of Medicine
AddressSan Francisco CA 94158
Phone415-353-7171
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    Other Positions
    Title(s)Stephen and Faith Brown Endowed Professor in Urology


    Collapse Biography 
    Collapse education and training
    Memorial Sloan Kettering Cancer Center, New York, NY06/2023Urologic Oncology
    University of California, San Francisco, San Francisco, CA06/2021Urologic Surgery
    University of California, San Francisco, San Francisco, CAM.D.06/2015Medicine
    University of California, San Diego, La Jolla, CAB.S. with Honors06/2010Human Biology
    Collapse awards and honors
    University of California, San Diego2006University of California Regents Scholar
    University of California, San Francisco2013Alpha Omega Alpha Medical Society
    Memorial Sloan Kettering Cancer Center2022American Society of Clinical Oncology Young Investigator Award
    Memorial Sloan Kettering Cancer Center2023Peter T. Scardino Award for Leadership

    Collapse Research 
    Collapse research activities and funding
    Enhancing Nectin-4 targeting therapy in urothelial carcinoma with retinoic acid
    American Association for Cancer Research Sep 1, 2025 - Aug 31, 2026
    Improved molecular imaging of urothelial cancer using immunoPET targeting CD46 and Nectin-4
    UCSF Helen Diller Family Comprehensive Cancer Center 2019699Jul 1, 2025 - Jun 30, 2026
    Description: Characterize the heterogeneity and distribution of CD46 and Nectin-4 protein expression across disease stages, upper tract UC, and in EV-resistant tumors and evaluate the feasibility of imaging using [89Zr]DFO-enfortumab and [89Zr]DFO-YS5 in preclinical models of urothelial cancer.
    UCSF Specialized Programs of Research Excellence (SPOREs) in Prostate Cancer
    NIH P50CA275741Sep 2, 2024 - Aug 31, 2029
    Role: Co-Investigator
    Percuflex Urinary Diversion Stents
    Boston Scientific A145168Jun 14, 2024 - Mar 3, 2026
    Role: Co-Investigator
    Description: Identify short term complications of single-J ureteral stents in a radical cystectomy cohort
    STEAP1-targeted immunotherapy in prostate cancer
    Prostate Cancer Foundation 24YOUN30Sep 1, 2022
    Role: Principal Investigator
    Description: Identify regulators of STEAP-1 expression and identify synergistic targets to STEAP-1 targeted immunotherapy
    UCSF Paul Calabresi K12 Career Development Program in Clinical Oncology
    NIH K12CA260225Jul 1, 2021 - Jun 30, 2026
    Role: Co-Investigator
    Clinical significance and regulation of PSMA expression in locally advanced high risk prostate cancer
    NIH 5TL1TR001871-04Jul 1, 2019 - Jun 30, 2020
    Role: Investigator
    T32 Urologic Oncology Research Training Grant
    NIH T32CA082088Sep 1, 1999 - Jul 31, 2030
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Modulating the PPARγ pathway upregulates NECTIN4 and enhances chimeric antigen receptor (CAR) T cell therapy in bladder cancer. Nat Commun. 2025 Sep 10; 16(1):8215. Chang K, Delavan HM, Yip E, Kasap C, Zhu J, Lodha R, Liao SY, Berman SC, Carretero-Gonzalez A, Basar M, Gokturk Ozcan G, Teo MY, Solit DB, Rosenberg JE, Al-Ahmadie H, Ding CCK, Chan E, Steri V, Porten SP, Koshkin VS, Friedlander TW, Feng FY, Lee JK, Wiita AP, Chu CE, Chou J. PMID: 40931013; PMCID: PMC12423289.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Clinical Outcomes, Genomic Heterogeneity, and Therapeutic Considerations Across Histologic Subtypes of Urothelial Carcinoma. Eur Urol. 2025 Nov; 88(5):472-481. Chu CE, Chen Z, Whiting K, Ostrovnaya I, Lenis AT, Clinton TN, Rammal R, Ozcan GG, Akbulut D, Basar M, Chen JF, Chen YB, Gopalan A, Fine SW, Tickoo SK, Arcila M, Brannon AR, Berger MF, Cha EK, Goh AC, Donahue TF, Bajorin DF, Teo MY, Rosenberg JE, Iyer G, Pietzak EJ, Bochner BH, Reuter VE, Sarungbam J, Solit DB, Al-Ahmadie H. PMID: 40288936; PMCID: PMC12353162.
      View in: PubMed   Mentions: 1     Fields:    
    3. HER2 overexpression in urothelial carcinoma with GATA3 and PPARG copy number gains. Oncologist. 2024 Aug 05; 29(8):e1094-e1097. Zhu X, Chan E, Turski ML, Mendez CE, Hsu SC, Kumar V, Shipp C, Jindal T, Chang K, Onodera C, Devine WP, Grenert JP, Stohr BA, Ding CC, Stachler MD, Quigley DA, Feng FY, Chu CE, Porten SP, Chou J, Friedlander TW, Koshkin VS. PMID: 38908022; PMCID: PMC11299940.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    4. Natural History and Genomic Landscape of Chemotherapy-Resistant Muscle-Invasive Bladder Cancer. JCO Precis Oncol. 2024 04; 8:e2300274. Lenis AT, Whiting K, Ravichandran V, Tallman JE, Alam SM, Chu CE, Jesus Escano M, Bochner E, Katims A, Reisz PA, Truong H, Clinton TN, Telis L, Dason S, McPherson V, Teo MY, Funt S, Aggen D, Goh AC, Donahue TF, Cha EK, Donat SM, Herr HW, Dalbagni G, Schultz N, Berger MF, Bajorin DF, Rosenberg JE, Bochner BH, Ostrovnaya I, Al-Ahmadie H, Solit DB, Iyer G, Pietzak EJ. PMID: 38691813; PMCID: PMC11310921.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Scratching the Surface: NECTIN-4 as a Surrogate for Enfortumab Vedotin Resistance. Clin Cancer Res. 2023 04 14; 29(8):1377-1380. Aggen DH, Chu CE, Rosenberg JE. PMID: 36749325; PMCID: PMC10106381.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    6. Prostate cancer disparities among American Indians and Alaskan Natives in the United States. J Natl Cancer Inst. 2023 04 11; 115(4):413-420. Chu CE, Leapman MS, Zhao S, Cowan JE, Washington SL, Cooperberg MR. PMID: 36629492; PMCID: PMC10086629.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    7. Cxbladder Monitor testing to reduce cystoscopy frequency in patients with bladder cancer. Urol Oncol. 2023 07; 41(7):326.e1-326.e8. Li KD, Chu CE, Patel M, Meng MV, Morgan TM, Porten SP. PMID: 36868882.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    8. Genomic heterogeneity as a barrier to precision oncology in urothelial cancer. Cell Rep. 2022 12 20; 41(12):111859. Clinton TN, Chen Z, Wise H, Lenis AT, Chavan S, Donoghue MTA, Almassi N, Chu CE, Dason S, Rao P, Rodrigues JA, Vasani NB, Ridouani F, Rosenberg JE, Bajorin DF, Teo MY, Bochner BH, Berger MF, Ostrovnaya I, Pietzak EJ, Iyer G, Gao SP, Hu W, Al-Ahmadie HA, Solit DB. PMID: 36543146; PMCID: PMC9882421.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    9. TROP2 Expression Across Molecular Subtypes of Urothelial Carcinoma and Enfortumab Vedotin-resistant Cells. Eur Urol Oncol. 2022 12; 5(6):714-718. Chou J, Trepka K, Sjöström M, Egusa EA, Chu CE, Zhu J, Chan E, Gibb EA, Badura ML, Contreras-Sanz A, Stohr BA, Meng MV, Pruthi RS, Lotan Y, Black PC, Porten SP, Koshkin VS, Friedlander TW, Feng FY. PMID: 35216942; PMCID: PMC10262920.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    10. A Cross-Sectional Analysis of Barriers Associated With Non-Attendance at a Urology Telehealth Clinic in a Safety-Net Hospital. Urology. 2022 04; 162:57-62. Bell A, Lonergan PE, Escobar D, Fakunle M, Chu CE, Berdy S, Palmer NR, Breyer BN, Washington SL. PMID: 34461145.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    11. Heterogeneity in NECTIN4 Expression Across Molecular Subtypes of Urothelial Cancer Mediates Sensitivity to Enfortumab Vedotin. Clin Cancer Res. 2021 09 15; 27(18):5123-5130. Chu CE, Sjöström M, Egusa EA, Gibb EA, Badura ML, Zhu J, Koshkin VS, Stohr BA, Meng MV, Pruthi RS, Friedlander TW, Lotan Y, Black PC, Porten SP, Feng FY, Chou J. PMID: 34108177; PMCID: PMC8634828.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCells
    12. Association of Age With Risk of Adverse Pathological Findings in Men Undergoing Delayed Radical Prostatectomy Following Active Surveillance. Urology. 2021 09; 155:91-95. de la Calle CM, Shee K, Chu CE, Cowan JE, Nguyen HG, Carroll PR. PMID: 34118228.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Prostate-specific Membrane Antigen and Fluciclovine Transporter Genes are Associated with Variable Clinical Features and Molecular Subtypes of Primary Prostate Cancer. Eur Urol. 2021 06; 79(6):717-721. Chu CE, Alshalalfa M, Sjöström M, Zhao SG, Liu Y, Chou J, Herlemann A, Mahal B, Kishan AU, Spratt DE, Cooperberg M, Small E, Wong A, Porten S, Hope TA, Ross AE, Davicioni E, Nguyen P, Karnes RJ, Carroll PR, Schaeffer E, Feng FY. PMID: 33840559.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    14. Diagnostic Accuracy and Prognostic Value of Serial Prostate Multiparametric Magnetic Resonance Imaging in Men on Active Surveillance for Prostate Cancer. Eur Urol Oncol. 2022 10; 5(5):537-543. Chu CE, Cowan JE, Lonergan PE, Washington SL, Fasulo V, de la Calle CM, Shinohara K, Westphalen AC, Carroll PR. PMID: 33483265.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    15. Liposomal Bupivacaine Decreases Postoperative Length of Stay and Opioid Use in Patients Undergoing Radical Cystectomy. Urology. 2021 Mar; 149:168-173. Chu CE, Law L, Zuniga K, Lin TK, Tsourounis C, Rodriguez-Monguio R, Lazar A, Washington SL, Cooperberg MR, Greene KL, Carroll PR, Pruthi RS, Meng MV, Chen LL, Porten SP. PMID: 33278460.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    16. The Clinical Significance of Multiple Negative Surveillance Prostate Biopsies for Men on Active Surveillance-Does Cancer Vanish or Simply Hide? J Urol. 2021 Jan; 205(1):109-114. Chu CE, Cowan JE, Fasulo V, Washington SL, de la Calle C, Shoemaker J, Carroll PR. PMID: 33198555.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Multiparametric Magnetic Resonance Imaging Alone is Insufficient to Detect Grade Reclassification in Active Surveillance for Prostate Cancer. Eur Urol. 2020 10; 78(4):515-517. Chu CE, Lonergan PE, Washington SL, Cowan JE, Shinohara K, Westphalen AC, Carroll PR, Cooperberg MR. PMID: 32631744.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    18. Re: Vasilis Stavrinides, Francesco Giganti, Bruce Trock, et al. Five-year Outcomes of Magnetic Resonance Imaging-based Active Surveillance for Prostate Cancer: A Large Cohort Study. Eur Urol 2020;78:443-51. Eur Urol. 2020 09; 78(3):e110-e111. Chu CE, Lonergan PE, Carroll PR. PMID: 32622551.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Role of Indoleamine-2,3-Dioxygenase Inhibitors in Salvage Therapy for Non-Muscle Invasive Bladder Cancer. Urol Clin North Am. 2020 Feb; 47(1):111-118. Chu CE, Porten SP, Grossfeld GD, Meng MV. PMID: 31757294.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    20. Hepatitis C Virus Treatment Access Among Human Immunodeficiency Virus and Hepatitis C Virus (HCV)-Coinfected People Who Inject Drugs in Guangzhou, China: Implications for HCV Treatment Expansion. Open Forum Infect Dis. 2016 Apr; 3(2):ofw065. Chu CE, Wu F, He X, Zhou K, Cheng Y, Cai W, Geng E, Volberding P, Tucker JD. PMID: 27419150; PMCID: PMC4943171.
      View in: PubMed   Mentions: 5  
    21. Quantified Clinical Risk Change as an End Point During Prostate Cancer Active Surveillance. Eur Urol. 2017 09; 72(3):329-332. Leapman MS, Ameli N, Cooperberg MR, Chu C, Hussein A, Shinohara K, Carroll PR. PMID: 27157998.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    22. Ultrasound-Guided Renal Access for Percutaneous Nephrolithotomy: A Description of Three Novel Ultrasound-Guided Needle Techniques. J Endourol. 2016 Feb; 30(2):153-8. Chu C, Masic S, Usawachintachit M, Hu W, Yang W, Stoller M, Li J, Chi T. PMID: 26414304; PMCID: PMC4761800.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansPHPublic Health
    23. Stakeholder Engagement in HIV Cure Research: Lessons Learned from Other HIV Interventions and the Way Forward. AIDS Patient Care STDS. 2015 Jul; 29(7):389-99. Lo YR, Chu C, Ananworanich J, Excler JL, Tucker JD. PMID: 26061668; PMCID: PMC4504439.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansPHPublic Health
    24. Trends, utilization, and immediate perioperative complications of urethroplasty in the United States: data from the national inpatient sample 2000-2010. Urology. 2015 May; 85(5):1190-1194. Blaschko SD, Harris CR, Zaid UB, Gaither T, Chu C, Alwaal A, McAninch JW, McCulloch CE, Breyer BN. PMID: 25746579; PMCID: PMC4917203.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    25. Exploring the social meaning of curing HIV: a qualitative study of people who inject drugs in Guangzhou, China. AIDS Res Hum Retroviruses. 2015 Jan; 31(1):78-84. Chu CE, Wu F, He X, Ma Q, Cheng Y, Cai W, Volberding P, Tucker JD. PMID: 25427547; PMCID: PMC4287130.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    26. Peripheral administration of translation inhibitors reverses increased hyperalgesia in a model of chronic pain in the rat. J Pain. 2013 Jul; 14(7):731-8. Ferrari LF, Bogen O, Chu C, Levine JD. PMID: 23664545; PMCID: PMC3700567.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    27. Phosphorylation of Rpt6 regulates synaptic strength in hippocampal neurons. J Neurosci. 2012 Apr 11; 32(15):5126-31. Djakovic SN, Marquez-Lona EM, Jakawich SK, Wright R, Chu C, Sutton MA, Patrick GN. PMID: 22496558; PMCID: PMC3348785.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    28. Generation of a pain memory in the primary afferent nociceptor triggered by PKCε activation of CPEB. J Neurosci. 2012 Feb 08; 32(6):2018-26. Bogen O, Alessandri-Haber N, Chu C, Gear RW, Levine JD. PMID: 22323716; PMCID: PMC3305286.
      View in: PubMed   Mentions: 90     Fields:    Translation:AnimalsCells
    29. Mitochondrial dependence of nerve growth factor-induced mechanical hyperalgesia. Pain. 2011 Aug; 152(8):1832-1837. Chu C, Levine E, Gear RW, Bogen O, Levine JD. PMID: 21570183; PMCID: PMC3161405.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
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