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    Shuvo Roy, PhD

    TitleProfessor
    SchoolUCSF School of Pharmacy
    DepartmentBioengineering and Therapeutic Sciences
    Address1700 4th Street
    San Francisco CA 94158
    Phone415-514-9666

       Biography 
       Awards and Honors
      Mount Union College1989William and Burdella Carl Mathematics Award
      Mount Union College1992Senior Physics Prize
      Case Western Reserve University1998Ruth Barber Moon Graduate Student Award
      Crain's Cleveland Business1999Top 40 Under 40
      BioMEMS and Biomedical Nanotechnology World Meeting2001Clinical Translation Award
      Technology Review Magazine2003MIT TR100 Award, Top 100 Young Innovators
      NASA2004NASA Group Achievement Award, Harsh Environment MEMS
      Materials Research Society2004Ribbon Award, Outstanding Symposium Paper, MRS Fall Meeting
      Crain's Cleveland Business2005Who's Who in Biotechnology
      Cleveland Clinic2005Cleveland Clinic Innovator Award
      Cleveland Clinic Science Internship Program2006Mentor Recognition Award
      Cleveland Clinic2007Cleveland Clinic Innovator Award
      Southwestern Surgical Congress2008Thomas G. Orr Memorial Lectureship
      Biotechnology Industry Organization2009Biotech Humanitarian Award Finalist
      Biomaterials Journal2009Images of the Year Selection
      Vodafone Americas Foundation2011mHealth Alliance Award
      University of California, San Francisco2012UCSF Outstanding Faculty Mentorship Award, Finalist
      BayBio Pantheon2012Rising Star Award
      Food and Drug Administration (FDA)2012Innovation Pathway 2.0 Award
      Applied Innovation Institute2013Fellow
      Heinz Awards2013Requested Nominator

       Overview 
       Overview
      Shuvo Roy, PhD, Professor, Bioengineering and Therapeutic Sciences, UC San Francisco. Dr. Roy focuses his research on the development of biomedical devices to address unmet clinical needs through the application of microelectromechanical systems (MEMS) and related nanotechnology. He is the director of the Biodesign Laboratory and is a faculty affiliate of the California Institute for Quantitative Biosciences (QB3). His research focuses on fabrication of silicon membranes for biofiltration and organ replacement functions, surface modification of MEMS substrates to enhance device biocompatibility, and wireless sensors for physiological monitoring. He is the technical director of The Kidney Project, a national research project to create a small, surgically implanted, and free-standing bioartificial kidney to treat end stage renal disease (ESRD). In addition, he is a founding member of the UCSF Pediatric Device Consortium, which has a mission to accelerate the development of innovative devices for children’s health. Before joining UC San Francisco in 2008, Dr. Roy co-directed the BioMEMS Laboratory in the Department of Biomedical Engineering at Cleveland Clinic in Cleveland, Ohio. He has a PhD in electrical engineering and computer science from Case Western Reserve University in Cleveland, Ohio.

      In 1992 he earned a BS degree, Magna Cum Laude, with General Honors for triple majors in Physics, Mathematics (Special Honors), and Computer Science from Mount Union College in Alliance, Ohio. In 1995, he earned an MS in Electrical Engineering and Applied Physics and, in 2001, a PhD degree in Electrical Engineering and Computer Science, both from Case Western Reserve University in Cleveland, Ohio.

      Dr. Roy has contributed more than 85 technical publications, co-authored 3 book chapters, been awarded 16 US patents, and given more than 60 invited presentations. He is the recipient of a Top 40 under 40 award by Crain’s Cleveland Business in 1999 and the Clinical Translation Award at the 2nd Annual BioMEMS and Biomedical Nanotechnology World 2001 meeting. In 2003, Dr. Roy was selected as a recipient of the TR100, which features the world’s 100 Top Young Innovators as selected by Technology Review, the Massachusetts Institute of Technology’s Magazine of Innovation. In 2004, he was presented with a NASA Group Achievement Award for his work on harsh environment MEMS. In 2005, Dr. Roy was named as a Who’s Who in Biotechnology by Crain’s Cleveland Business. In 2005 and 2007, he was recognized as a Cleveland Clinic Innovator. In 2009, he was nominated for the Biotechnology Industry Organization's Biotech Humanitarian Award, which is given in recognition of an individual who has used biotechnology to unlock its potential to improve the earth.

       Interests
      Therapeutics, Bioengineering, Medical Devices, Microelectromechanical Systems, BioMEMS, Sensors, Transducers, Biocompatibility, Artificial Organs, Microtextured Substrates, Renal Replacement, Tissue Engineering, Nanotechnology, Artificial Kidney

       ORNG Applications 
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       Bibliographic 
       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Kim S, Roy S. Microelectromechanical systems and nephrology: the next frontier in renal replacement technology. Adv Chronic Kidney Dis. 2013 Nov; 20(6):516-35.
        View in: PubMed
      2. Kim EJ, Fleischman AJ, Muschler GF, Roy S. Response of bone marrow derived connective tissue progenitor cell morphology and proliferation on geometrically modulated microtextured substrates. Biomed Microdevices. 2013 Jun; 15(3):385-96.
        View in: PubMed
      3. Fissell WH, Roy S, Davenport A. Achieving more frequent and longer dialysis for the majority: wearable dialysis and implantable artificial kidney devices. Kidney Int. 2013 Aug; 84(2):256-64.
        View in: PubMed
      4. Etemadi M, Chung P, Heller JA, Liu J, Grossman-Kahn R, Rand L, Roy S. Novel device to trend impedance and fluorescence of the cervix for preterm birth detection. Conf Proc IEEE Eng Med Biol Soc. 2013; 2013:176-9.
        View in: PubMed
      5. Chung P, Rowe A, Etemadi M, Lee H, Roy S. Fabric-based pressure sensor array for decubitus ulcer monitoring. Conf Proc IEEE Eng Med Biol Soc. 2013; 2013:6506-9.
        View in: PubMed
      6. Etemadi M, Heller JA, Schecter SC, Shue EH, Miniati D, Roy S. Implantable ultra-low pulmonary pressure monitoring system for fetal surgery. IEEE Trans Inf Technol Biomed. 2012 Nov; 16(6):1208-15.
        View in: PubMed
      7. Jelin EB, Etemadi M, Encinas J, Schecter SC, Chapin C, Wu J, Guevara-Gallardo S, Nijagal A, Gonzales KD, Ferrier WT, Roy S, Miniati D. Dynamic tracheal occlusion improves lung morphometrics and function in the fetal lamb model of congenital diaphragmatic hernia. J Pediatr Surg. 2011 Jun; 46(6):1150-7.
        View in: PubMed
      8. Muthusubramaniam L, Lowe R, Fissell WH, Li L, Marchant RE, Desai TA, Roy S. Hemocompatibility of silicon-based substrates for biomedical implant applications. Ann Biomed Eng. 2011 Apr; 39(4):1296-305.
        View in: PubMed
      9. Ferrell N, Desai RR, Fleischman AJ, Roy S, Humes HD, Fissell WH. A microfluidic bioreactor with integrated transepithelial electrical resistance (TEER) measurement electrodes for evaluation of renal epithelial cells. Biotechnol Bioeng. 2010 Nov 1; 107(4):707-16.
        View in: PubMed
      10. Ferrell N, Groszek J, Li L, Smith R, Butler RS, Zorman CA, Roy S, Fissell WH. Basal lamina secreted by MDCK cells has size- and charge-selective properties. Am J Physiol Renal Physiol. 2011 Jan; 300(1):F86-90.
        View in: PubMed
      11. Chandrana C, Talman J, Pan T, Roy S, Fleischman A. Design and analysis of MEMS based PVDF ultrasonic transducers for vascular imaging. Sensors (Basel). 2010; 10(9):8740-50.
        View in: PubMed
      12. Groszek J, Li L, Ferrell N, Smith R, Zorman CA, Hofmann CL, Roy S, Fissell WH. Molecular conformation and filtration properties of anionic Ficoll. Am J Physiol Renal Physiol. 2010 Oct; 299(4):F752-7.
        View in: PubMed
      13. Melvin ME, Fissell WH, Roy S, Brown DL. Silicon induces minimal thromboinflammatory response during 28-day intravascular implant testing. ASAIO J. 2010 Jul-Aug; 56(4):344-8.
        View in: PubMed
      14. Chandrana C, Kharin N, Vince G, Roy S, Fleischman A. Demonstration of second-harmonic IVUS feasibility with focused broadband miniature transducers. IEEE Trans Ultrason Ferroelectr Freq Control. 2010 May; 57(5):1077-85.
        View in: PubMed
      15. Datta S, Conlisk AT, Kanani DM, Zydney AL, Fissell WH, Roy S. Characterizing the surface charge of synthetic nanomembranes by the streaming potential method. J Colloid Interface Sci. 2010 Aug 1; 348(1):85-95.
        View in: PubMed
      16. Fissell WH, Roy S. The implantable artificial kidney. Semin Dial. 2009 Nov-Dec; 22(6):665-70.
        View in: PubMed
      17. Kim EJ, Boehm CA, Fleischman AJ, Muschler GF, Kostov YV, Roy S. Modulating human connective tissue progenitor cell behavior on cellulose acetate scaffolds by surface microtextures. J Biomed Mater Res A. 2009 Sep 15; 90(4):1198-205.
        View in: PubMed
      18. Fissell WH, Hofmann CL, Ferrell N, Schnell L, Dubnisheva A, Zydney AL, Yurchenco PD, Roy S. Solute partitioning and filtration by extracellular matrices. Am J Physiol Renal Physiol. 2009 Oct; 297(4):F1092-100.
        View in: PubMed
      19. Kim EJ, Boehm CA, Mata A, Fleischman AJ, Muschler GF, Roy S. Post microtextures accelerate cell proliferation and osteogenesis. Acta Biomater. 2010 Jan; 6(1):160-9.
        View in: PubMed
      20. Mata A, Kim EJ, Boehm CA, Fleischman AJ, Muschler GF, Roy S. A three-dimensional scaffold with precise micro-architecture and surface micro-textures. Biomaterials. 2009 Sep; 30(27):4610-7.
        View in: PubMed
      21. Conlisk AT, Datta S, Fissell WH, Roy S. Biomolecular transport through hemofiltration membranes. Ann Biomed Eng. 2009 Apr; 37(4):722-36.
        View in: PubMed
      22. Nath P, Strelnik J, Vasanji A, Moore LR, Williams PS, Zborowski M, Roy S, Fleischman AJ. Development of multistage magnetic deposition microscopy. Anal Chem. 2009 Jan 1; 81(1):43-9.
        View in: PubMed
      23. Ferrara LA, Gordon I, Coquillette M, Milks R, Fleischman AJ, Roy S, Goel VK, Benzel EC. A preliminary biomechanical evaluation in a simulated spinal fusion model. Laboratory investigation. J Neurosurg Spine. 2007 Nov; 7(5):542-8.
        View in: PubMed
      24. Melnik K, Sun J, Fleischman A, Roy S, Zborowski M, Chalmers JJ. Quantification of magnetic susceptibility in several strains of Bacillus spores: implications for separation and detection. Biotechnol Bioeng. 2007 Sep 1; 98(1):186-92.
        View in: PubMed
      25. Fissell WH, Manley S, Dubnisheva A, Glass J, Magistrelli J, Eldridge AN, Fleischman AJ, Zydney AL, Roy S. Ficoll is not a rigid sphere. Am J Physiol Renal Physiol. 2007 Oct; 293(4):F1209-13.
        View in: PubMed
      26. Fissell WH, Fleischman AJ, Humes HD, Roy S. Development of continuous implantable renal replacement: past and future. Transl Res. 2007 Dec; 150(6):327-36.
        View in: PubMed
      27. Mata A, Boehm C, Fleischman AJ, Muschler GF, Roy S. Connective tissue progenitor cell growth characteristics on textured substrates. Int J Nanomedicine. 2007; 2(3):389-406.
        View in: PubMed
      28. Fissell WH, Manley S, Westover A, Humes HD, Fleischman AJ, Roy S. Differentiated growth of human renal tubule cells on thin-film and nanostructured materials. ASAIO J. 2006 May-Jun; 52(3):221-7.
        View in: PubMed
      29. Smiechowski MF, Lvovich VF, Roy S, Fleischman A, Fissell WH, Riga AT. Electrochemical detection and characterization of proteins. Biosens Bioelectron. 2006 Dec 15; 22(5):670-7.
        View in: PubMed
      30. Schneider T, Moore LR, Jing Y, Haam S, Williams PS, Fleischman AJ, Roy S, Chalmers JJ, Zborowski M. Continuous flow magnetic cell fractionation based on antigen expression level. J Biochem Biophys Methods. 2006 Jul 31; 68(1):1-21.
        View in: PubMed
      31. Talman JR, Fleischman AJ, Roy S. Orthogonal-coil RF probe for implantable passive sensors. IEEE Trans Biomed Eng. 2006 Mar; 53(3):538-46.
        View in: PubMed
      32. Lopez CA, Fleischman AJ, Roy S, Desai TA. Evaluation of silicon nanoporous membranes and ECM-based microenvironments on neurosecretory cells. Biomaterials. 2006 Jun; 27(16):3075-83.
        View in: PubMed
      33. Benzel EC, Kayanja M, Fleischman A, Roy S. Spine biomechanics: fundamentals and future. Clin Neurosurg. 2006; 53:98-105.
        View in: PubMed
      34. Mata A, Fleischman AJ, Roy S. Characterization of polydimethylsiloxane (PDMS) properties for biomedical micro/nanosystems. Biomed Microdevices. 2005 Dec; 7(4):281-93.
        View in: PubMed
      35. Nath P, Roy S, Conlisk T, Fleischman AJ. A system for micro/nano fluidic flow diagnostics. Biomed Microdevices. 2005 Sep; 7(3):169-77.
        View in: PubMed
      36. Benzel E, Ferrara L, Roy S, Fleischman A. Micromachines in spine surgery. Spine (Phila Pa 1976). 2004 Mar 15; 29(6):601-6.
        View in: PubMed
      37. Mata A, Su X, Fleischman AJ, Roy S, Banks BA, Miller SK, Midura RJ. Osteoblast attachment to a textured surface in the absence of exogenous adhesion proteins. IEEE Trans Nanobioscience. 2003 Dec; 2(4):287-94.
        View in: PubMed
      38. Mata A, Boehm C, Fleischman AJ, Muschler G, Roy S. Growth of connective tissue progenitor cells on microtextured polydimethylsiloxane surfaces. J Biomed Mater Res. 2002 Dec 15; 62(4):499-506.
        View in: PubMed
      39. Mata A, Boehm C, Fleischman AJ, Muschler G, Roy S. Analysis of connective tissue progenitor cell behavior on polydimethylsiloxane smooth and channel micro-textures. Biomed Microdevices. 2002 Dec; 4(4):267-75.
        View in: PubMed
      40. Kotzar G, Freas M, Abel P, Fleischman A, Roy S, Zorman C, Moran JM, Melzak J. Evaluation of MEMS materials of construction for implantable medical devices. Biomaterials. 2002 Jul; 23(13):2737-50.
        View in: PubMed
      41. Benzel EC, Ferrara LA, Roy S, Fleischman AJ. Biomaterials and implantable devices: discoveries in the spine surgery arena. Clin Neurosurg. 2002; 49:209-25.
        View in: PubMed
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