Thomas Lang, PhD
|Title||Associate Dean for Research|
|School||UCSF School of Medicine|
|Address||185 Berry St B N|
San Francisco CA 94107
|Title||School of Dentistry|
|Title||Professor in Residence|
|Title||Radiology and Biomedical Imaging|
|NIH Center for Scientific Review, ZRG1-MOSS-C56 DP2, Director's New Innovator Award Study Section||2014||Editorial Reviewer|
|American Institute of Medical and Biological Engineering||2014||Fellow|
|Academy of Radiology Research||2013||Distinguished Investigator Award|
|American Astronautical Society/NASA||2013||International Space Station Top Discoveries in Microgravity Award|
|Journal of Bone and Mineral Research||2013||Associate Editor|
|Osteoporosis International||2013||2012 Citation Prize|
|American Federation for Aging Research||2012||Member, Scientific Advisory Board|
|Journal of Bone and Mineral Research||2010
|NIH Center for Scientific Review, ZRG1 DTCS-A81 Imaging Study Section||2011||Editorial Reviewer|
|University of California, San Francisco||2010||Conflict of Interest Advisory Committee Chairman|
|NIH Center for Scientific Review||2009
||2013||Skeletal Biology, Structure and Regeneration Study Section|
|National Space Biomedical Research Institute||2008
||2012||Musculoskeletal Alterations Team Leader|
|American Society of Bone and Mineral Research||2007||Bridge Funding Grant Award|
|Faculty of Medicine, University of Buenos Aires||2004||Visiting Professor|
|World Congress on Osteoporosis||1995||Young Investigator Award|
Thomas F. Lang, PhD, is a Professor in Residence, a faculty member of the Musculoskeletal Quantitative Imaging Research Group, and he leads the Musculoskeletal CT Imaging Research Group at the University of California, San Francisco. Since 2010, Dr. Lang has served as Chair of the UCSF Chancellor’s Conflict of Interest Advisory Committee. Clinically, Dr. Lang and his colleagues are establishing a research program using CT and PET/CT to measure physical traits, muscle size, adiposity, and protein synthesis rate as markers of frailty. Dr. Lang obtained his BA in Chemistry at the University of Chicago in 1983, and completed his PhD in Chemistry at the University of California, Berkeley in 1990, followed by a postdoctoral fellowship in Radiology Imaging at UCSF in 1992.
The focus of Dr Lang's Research is to develop quantitative analytic methods centered on bettering our understanding of two major chronic problems that affect the growing elderly population: osteoporosis, a main cause of age-related fractures, and sarcopenia, a loss of skeletal muscle strength, endurance and function. The aim of this research is to characterize skeletal density, geometry and indices of strength from volumetric CT scans of the hip and spine, as well as similar imaging based methods to quantify skeletal muscle anatomy and function. With the growth of his research group, Dr. Lang and his group have continued a robust program in methods development, integrating density and structured analysis with serial image registration to improve sensitivity for detecting changes in longitudinal measures, and finite element modeling in order to understand how density and structure measures of bones are related to bone strength, stiffness, and factures.
Presently, Dr. Lang is principal investigator on two NIH R01 projects and is collaborating with NASA Johnson Space Center’s using quantitative assessments to study the effect of long-duration spaceflight and prolonged mechanical unloading on skeletal density, structure, and strength. Dr. Lang has served as Principal Investigator and Co-Principal Investigator of many NIH grants. He has over 110 published articles, in addition to other contributions including patents, review articles and book chapters.
Osteoporosis and Musculoskeletal
Bone aging, quantitative computed tomography, sarcopenia
Osteoporosis, computed tomography, bone mineral density measurements, CT and PET/CT imaging in the study of the human biology of the musculoskeletal system
Education and Training:
• Bachelor of Art: University of Chicago - Chemistry
• Doctor of Philosophy: University of California, Berkeley - Chemistry
• Postdoctoral Fellowship: University of California, San Francisco - Radiology Imaging
• UCSF/Coro Leadership Collaborative Program
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