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Michael Aminoff, MD, DSc

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentNeurology
Address505 Parnassus Avenue
San Francisco CA 94143
Phone415-353-1940
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    Collapse Biography 
    Collapse Education and Training
    University College London, UKBSc (Hons)1962Anatomy
    University College Hospital Medical School, London, UKMB, BS (equivalent to an American MD degree)1965Medicine and Surgery
    Institute of Neurology & University College London, London, UKMD (research thesis)1973Neurophysiology
    University College London, London, UKDSc2000Electrophysiological studies of the human nervous system
    American Board of Psychiatry & Neurology1982 Neurology
    American Board of Psychiatry & Neurology1992Clinical Neurophysiology
    American Board of Psychiatry & Neurology2004Neuroogy (voluntary re-certification)
    Collapse Awards and Honors
    American Academy of Neurology2007A.B.Baker Award
    Am Assoc Neuromuscular & Electrdiag Med2006Lifetime Achievement Award
    UCSF1990J. Elliott Royer Award for contributions to neurology
    Institute of Neurology, London, UK1973Queen Square Prize for Research in Neurology,

    Collapse Overview 
    Collapse Overview
    Dr Aminoff was born and educated in England, graduating from University College London in 1962 and as a physician from University College Hospital Medical School in 1965. He subsequently trained in neurology and clinical neurophysiology at The National Hospital for Neurology and Neurosurgery (Queen Square) in London, and also undertook basic research on spinal physiology at its affiliated Institute of Neurology, which led to the award of an MD degree (in the UK, an advanced medical degree based upon research) on completion of his thesis. In 1974, he moved from England to the UCSF School of Medicine in California, where he has been Professor of Neurology since 1982. He was Director of the Clinical Neurophysiology Laboratories at UCSF until July 2004, when he stepped down to assume the role of Executive Vice Chair of the Department of Neurology (2004-2017). He is director of the Parkinson’s Disease Clinic and Research Center. He is involved in a number of clinical trials and physiological studies of patients with movement disorders.

    Dr. Aminoff is the author of over 230 published medical or scientific articles, as well as the author or editor of some 30 books, many of which have gone into several editions, and of numerous chapters on topics related to neurology. His published scientific contributions led to the award of a Doctorate in Science, an advanced doctorate in the Faculty of Science, by the University of London in 2000. He is the one of the two editors-in-chief of the four-volume Encyclopedia of the Neurological Sciences published by Academic Press in 2003, with a second edition published in 2014, and is one of the series editors of the prestigious, multi-volume Handbook of Clinical Neurology (Elsevier). He was Editor-in Chief of the journal Muscle & Nerve for 10 years (1998-2007) and has also served on numerous other editorial boards. His other interests include medical history, and his biography of Brown-Séquard (Brown-Séquard: An Improbable genius Who Transformed Medicine) was published in 2010, and of Sir Charles Bell in 2017, by Oxford University Press.

    Dr. Aminoff was for 8 years a Director of the American Board of Psychiatry & Neurology, serving as Chair in 2011. He is married and has three children—one is a pediatric rheumatologist in Oakland, another is an attorney and deputy Federal Public Defender in Los Angeles, and the third is a prosecutor in the Department of Justice in Washington, DC.


    Collapse Research 
    Collapse Research Activities and Funding
    An open-label safety study of instrastriatal infusion of adeno-associated virus encoding human aromatic L-amino acid decarboxylase in subjects with advanced Parkinson’s disease.
    Genzyme Dec 1, 2006 - Jun 30, 2015
    Role: PI
    Role Description: PI of study to assess the safety of gene transfer in Parkinson’s disease
    Parkinson's Disease Neuroprotection Clinical Trial
    NIH/NINDS U10NS044460Sep 15, 2002 - Nov 30, 2015
    Role: Principal Investigator
    Parkinson's Disease Center-of-Excellence
    National Parkinson's Foundation Jul 1, 1992 - Jun 30, 2017
    Role: PI
    General Clinical Research Center
    NIH/NCRR M01RR000079Dec 1, 1974 - Mar 31, 2009
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Aminoff M. Future of Neurologic Examination in Clinical Practice-Reply. JAMA Neurol. 2018 Mar 01; 75(3):384. PMID: 29435562.
      View in: PubMed
    2. Aminoff M, Boller F, Swaab DF. Foreword. Handb Clin Neurol. 2018; 150:vii-viii. PMID: 29496160.
      View in: PubMed
    3. Aminoff M, Boller F, Swaab DF. Foreword. Handb Clin Neurol. 2018; 152:ix. PMID: 29604988.
      View in: PubMed
    4. Aminoff M, Boller F, Swaab DF. Foreword. Handb Clin Neurol. 2018; 148:vii. PMID: 29478619.
      View in: PubMed
    5. Aminoff M, Boller F, Swaab DF. Foreword. Handb Clin Neurol. 2018; 151:vii. PMID: 29519483.
      View in: PubMed
    6. Aminoff M, Boller F, Swaab DF. Foreword. Handb Clin Neurol. 2018; 149:vii. PMID: 29307366.
      View in: PubMed
    7. Aminoff M, Boller F, Swaab DF. Foreword. Handb Clin Neurol. 2018; 147:vii. PMID: 29325632.
      View in: PubMed
    8. Aminoff M. The Future of the Neurologic Examination. JAMA Neurol. 2017 Nov 01; 74(11):1291-1292. PMID: 28973109.
      View in: PubMed
    9. Aminoff M. The life and legacy of Brown-Séquard. Brain. 2017 May 01; 140(5):1525-1532. PMID: 29050371.
      View in: PubMed
    10. Gibbons CH, Simon DK, Huang M, Tilley B, Aminoff M, Bainbridge JL, Brodsky M, Freeman R, Goudreau J, Hamill RW, Luo ST, Singer C, Videnovic A, Bodis-Wollner I, Wong PS. Autonomic and electrocardiographic findings in Parkinson's disease. Auton Neurosci. 2017 07; 205:93-98. PMID: 28506500.
      View in: PubMed
    11. Chou KL, Elm JJ, Wielinski CL, Simon DK, Aminoff M, Christine CW, Liang GS, Hauser RA, Sudarsky L, Umeh CC, Voss T, Juncos J, Fang JY, Boyd JT, Bodis-Wollner I, Mari Z, Morgan JC, Wills AM, Lee SL, Parashos SA. Factors associated with falling in early, treated Parkinson's disease: The NET-PD LS1 cohort. J Neurol Sci. 2017 Jun 15; 377:137-143. PMID: 28477684.
      View in: PubMed
    12. Simon DK, Wu C, Tilley BC, Lohmann K, Klein C, Payami H, Wills AM, Aminoff M, Bainbridge J, Dewey R, Hauser RA, Schaake S, Schneider JS, Sharma S, Singer C, Tanner CM, Truong D, Wei P, Wong PS, Yang T. Caffeine, creatine, GRIN2A and Parkinson's disease progression. J Neurol Sci. 2017 Apr 15; 375:355-359. PMID: 28320167.
      View in: PubMed
    13. Aminoff M, Boller F, Swaab DF. Foreword. Handb Clin Neurol. 2017; 146:vii. PMID: 29110784.
      View in: PubMed
    14. Aminoff M, Boller F, Swaab DF. Foreword. Handb Clin Neurol. 2017; 145:vii. PMID: 28987200.
      View in: PubMed
    15. Aminoff M, Boller F, Swaab DF. Foreword. Handb Clin Neurol. 2017; 144:vii. PMID: 28947131.
      View in: PubMed
    16. Hauser RA, Li R, Pérez A, Ren X, Weintraub D, Elm J, Goudreau JL, Morgan JC, Fang JY, Aminoff M, Christine CW, Dhall R, Umeh CC, Boyd JT, Stover N, Leehey M, Zweig RM, Nicholas AP, Bodis-Wollner I, Willis A, Kieburtz K, Tilley BC. Longer Duration of MAO-B Inhibitor Exposure is Associated with Less Clinical Decline in Parkinson's Disease: An Analysis of NET-PD LS1. J Parkinsons Dis. 2017; 7(1):117-127. PMID: 27911341.
      View in: PubMed
    17. Aminoff M. Review of Merritt's Neurology, 13th ed. JAMA Neurol. 2016 Jun 01; 73(6):763. PMID: 27295286.
      View in: PubMed
    18. Goudreau JL, Pérez A, Aminoff M, Boyd JT, Burau KD, Christine CW, Leehey M, Morgan JC. Choice of dopaminergic therapy among early, mild Parkinson disease subjects in North America. J Neurol Sci. 2016 Jul 15; 366:74-81. PMID: 27288780.
      View in: PubMed
    19. Simon DK, Wu C, Tilley BC, Wills AM, Aminoff M, Bainbridge J, Hauser RA, Schneider JS, Sharma S, Singer C, Tanner CM, Truong D, Wong PS. Caffeine and Progression of Parkinson Disease: A Deleterious Interaction With Creatine. Clin Neuropharmacol. 2015 Sep-Oct; 38(5):163-9. PMID: 26366971; PMCID: PMC4573899.
    20. Bega D, Luo S, Fernandez H, Chou K, Aminoff M, Parashos S, Walker H, Russell DS, Christine CW, Dhall R, Singer C, Bodis-Wollner I, Hamill R, Truong D, Mari Z, Glazmann S, Huang M, Houston E, Simuni T. Impact of Depression on Progression of Impairment and Disability in Early Parkinson's Disease. Mov Disord Clin Pract. 2015 Dec; 2(4):371-378. PMID: 28393083.
      View in: PubMed
    21. Effect of creatine monohydrate on clinical progression in patients with Parkinson disease: a randomized clinical trial. JAMA. 2015 Feb 10; 313(6):584-93. PMID: 25668262; PMCID: PMC4349346.
    22. Lotti M, Aminoff M. Evaluating suspected work-related neurologic disorders (clinical diagnosis). Handb Clin Neurol. 2015; 131:9-21. PMID: 26563780.
      View in: PubMed
    23. Fang JY, Pérez A, Christine CW, Leehey M, Aminoff M, Boyd JT, Morgan JC, Dhall R, Nicholas AP, Bodis-Wollner I, Zweig RM, Goudreau JL. Parkinson's disease severity and use of dopaminergic medications. Parkinsonism Relat Disord. 2015 Mar; 21(3):297-9. PMID: 25541182; PMCID: PMC4340731.
    24. Aminoff M, Boller F, Swaab DF. Letter to the editor: comment on Koehler and Stahnisch's (2014) "three twentieth-century multiauthored neurological handbooks". J Hist Neurosci. 2014; 23(4):420-1. PMID: 25317491.
      View in: PubMed
    25. Dhand A, Aminoff M. The neurology of itch. Brain. 2014 Feb; 137(Pt 2):313-22. PMID: 23794605.
      View in: PubMed
    26. Fanara P, Wong PY, Husted KH, Liu S, Liu VM, Kohlstaedt LA, Riiff T, Protasio JC, Boban D, Killion S, Killian M, Epling L, Sinclair E, Peterson J, Price RW, Cabin DE, Nussbaum RL, Brühmann J, Brandt R, Christine CW, Aminoff M, Hellerstein MK. Cerebrospinal fluid-based kinetic biomarkers of axonal transport in monitoring neurodegeneration. J Clin Invest. 2012 Sep; 122(9):3159-69. PMID: 22922254; PMCID: PMC3428100.
    27. Mittermeyer G, Christine CW, Rosenbluth KH, Baker SL, Starr P, Larson P, Kaplan PL, Forsayeth J, Aminoff M, Bankiewicz KS. Long-term evaluation of a phase 1 study of AADC gene therapy for Parkinson's disease. Hum Gene Ther. 2012 Apr; 23(4):377-81. PMID: 22424171; PMCID: PMC4530392.
    28. Gottwald MD, Aminoff M. Therapies for dopaminergic-induced dyskinesias in Parkinson disease. Ann Neurol. 2011 Jun; 69(6):919-27. PMID: 21681795.
      View in: PubMed
    29. Chou KL, Zamudio J, Schmidt P, Price CC, Parashos SA, Bloem BR, Lyons KE, Christine CW, Pahwa R, Bodis-Wollner I, Oertel WH, Suchowersky O, Aminoff M, Malaty IA, Friedman JH, Okun MS. Hospitalization in Parkinson disease: a survey of National Parkinson Foundation Centers. Parkinsonism Relat Disord. 2011 Jul; 17(6):440-5. PMID: 21458353; PMCID: PMC3895941.
    30. Aminoff M, Christine CW, Friedman JH, Chou KL, Lyons KE, Pahwa R, Bloem BR, Parashos SA, Price CC, Malaty IA, Iansek R, Bodis-Wollner I, Suchowersky O, Oertel WH, Zamudio J, Oberdorf J, Schmidt P, Okun MS. Management of the hospitalized patient with Parkinson's disease: current state of the field and need for guidelines. Parkinsonism Relat Disord. 2011 Mar; 17(3):139-45. PMID: 21159538; PMCID: PMC3070297.
    31. Forsayeth J, Bankiewicz KS, Aminoff M. Gene therapy for Parkinson's disease: where are we now and where are we going? Expert Rev Neurother. 2010 Dec; 10(12):1839-45. PMID: 21091315.
      View in: PubMed
    32. Valles F, Fiandaca MS, Eberling JL, Starr PA, Larson PS, Christine CW, Forsayeth J, Richardson RM, Su X, Aminoff M, Bankiewicz KS. Qualitative imaging of adeno-associated virus serotype 2-human aromatic L-amino acid decarboxylase gene therapy in a phase I study for the treatment of Parkinson disease. Neurosurgery. 2010 Nov; 67(5):1377-85. PMID: 20871425.
      View in: PubMed
    33. Tien I, Glaser SD, Aminoff M. Characterization of gait abnormalities in Parkinson's disease using a wireless inertial sensor system. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:3353-6. PMID: 21097233.
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    34. Douglas VC, DeArmond SJ, Aminoff M, Miller BL, Rabinovici GD. Seizures in corticobasal degeneration: a case report. Neurocase. 2009 Aug; 15(4):352-6. PMID: 19544144; PMCID: PMC2829102.
    35. Tien I, Glaser SD, Bajcsy R, Goodin DS, Aminoff M. Results of using a wireless inertial measuring system to quantify gait motions in control subjects. IEEE Trans Inf Technol Biomed. 2010 Jul; 14(4):904-15. PMID: 19423449.
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    36. Aminoff M, Boller F, Swaab DF. Clinical neurology and stroke. Foreword. Handb Clin Neurol. 2009; 93:vii. PMID: 18804662.
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    37. Aminoff M, Boller F, Swaab DF. Part III: investigation and management. Foreword. Handb Clin Neurol. 2009; 94:vii. PMID: 18793884.
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    38. Aminoff M, Boller F, Swaab DF. Part I: basic and epidemiologycal aspects. Foreword. Handb Clin Neurol. 2009; 92:vii. PMID: 18790266.
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    39. Ralph JW, Goodin DS, Long JM, Aminoff M. Electrical brain events associated with awareness of errors. Brain Res. 2009 Jan 28; 1251:213-22. PMID: 19046953.
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    40. Gottwald MD, Aminoff M. New frontiers in the pharmacological management of Parkinson's disease. Drugs Today (Barc). 2008 Jul; 44(7):531-45. PMID: 18806903.
      View in: PubMed
    41. Simon DK, Swearingen CJ, Hauser RA, Trugman JM, Aminoff M, Singer C, Truong D, Tilley BC. Caffeine and progression of Parkinson disease. Clin Neuropharmacol. 2008 Jul-Aug; 31(4):189-96. PMID: 18670242; PMCID: PMC3056438.
    42. Aminoff M. Training in neurology. Neurology. 2008 May 13; 70(20):1912-5. PMID: 18474847.
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    43. Aminoff M, Boller F, Swaab DF. The dementias. Foreword. Handb Clin Neurol. 2008; 89:vii. PMID: 18631726.
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    44. Aminoff M, Goodin DS. Electrophysiological evaluation of dementia. Handb Clin Neurol. 2008; 89:63-74. PMID: 18631731.
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    45. Aminoff M, Boller F, Swaab DF. Neuropsychology and behavior. Foreword. Handb Clin Neurol. 2008; 88:vii. PMID: 18631683.
      View in: PubMed
    46. Aminoff M, Massey JM, Scheiber SC, Juul D. Certification in neuromuscular medicine: a new neurologic subspecialty. Neurology. 2007 Apr 03; 68(14):1153-4. PMID: 17404199.
      View in: PubMed
    47. Aminoff M, Massey JM, Scheiber SC, Juul D. Certification in neuromuscular medicine: a new neurologic subspecialty. Muscle Nerve. 2007 Apr; 35(4):409-10. PMID: 17385217.
      View in: PubMed
    48. Nakamura K, Aminoff M. Huntington's disease: clinical characteristics, pathogenesis and therapies. Drugs Today (Barc). 2007 Feb; 43(2):97-116. PMID: 17353947.
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    49. Aminoff M. Treatment should not be initiated too soon in Parkinson's disease. Ann Neurol. 2006 Mar; 59(3):562-4; discussion 564-5. PMID: 16489613.
      View in: PubMed
    50. Aminoff M. Electronic processing of manuscripts. Muscle Nerve. 2006 Mar; 33(3):301. PMID: 16566031.
      View in: PubMed
    51. Dowling GA, Mastick J, Colling E, Carter JH, Singer CM, Aminoff M. Melatonin for sleep disturbances in Parkinson's disease. Sleep Med. 2005 Sep; 6(5):459-66. PMID: 16084125.
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    52. Weiskopf RB, Toy P, Hopf HW, Feiner J, Finlay HE, Takahashi M, Bostrom A, Songster C, Aminoff M. Acute isovolemic anemia impairs central processing as determined by P300 latency. Clin Neurophysiol. 2005 May; 116(5):1028-32. PMID: 15826842.
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    53. Lieberman MA, Winzelberg A, Golant M, Wakahiro M, DiMinno M, Aminoff M, Christine C. Online support groups for Parkinson's patients: a pilot study of effectiveness. Soc Work Health Care. 2005; 42(2):23-38. PMID: 16390834.
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    54. Christine CW, Aminoff M. Clinical differentiation of parkinsonian syndromes: prognostic and therapeutic relevance. Am J Med. 2004 Sep 15; 117(6):412-9. PMID: 15380498.
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    55. Assaf BA, Karkar KM, Laxer KD, Garcia PA, Austin EJ, Barbaro NM, Aminoff M. Magnetoencephalography source localization and surgical outcome in temporal lobe epilepsy. Clin Neurophysiol. 2004 Sep; 115(9):2066-76. PMID: 15294209.
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    56. Aminoff M. Electrophysiologic testing for the diagnosis of peripheral nerve injuries. Anesthesiology. 2004 May; 100(5):1298-303. PMID: 15114229.
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    57. Aminoff M. EEG monitoring of comatose patients in the intensive care unit. Suppl Clin Neurophysiol. 2004; 57:662-6. PMID: 16106668.
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    58. Leppert D, Goodin DS, Aminoff M. Stimulus recognition and its relationship to the cerebral event-related potential. Neurology. 2003 Dec 09; 61(11):1533-7. PMID: 14663038.
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    59. Aminoff M. Neuroprotective treatment for Parkinson's disease. Expert Rev Neurother. 2003 Nov; 3(6):797-804. PMID: 19810882.
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    60. Assaf BA, Karkar KM, Laxer KD, Garcia PA, Austin EJ, Barbaro NM, Aminoff M. Ictal magnetoencephalography in temporal and extratemporal lobe epilepsy. Epilepsia. 2003 Oct; 44(10):1320-7. PMID: 14510826.
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    61. Weiskopf RB, Aminoff M, Hopf HW, Feiner J, Viele MK, Watson JJ, Ho R, Songster C, Toy P. Acute isovolemic anemia does not impair peripheral or central nerve conduction. Anesthesiology. 2003 Sep; 99(3):546-51. PMID: 12960537.
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    62. O'Neill J, Schuff N, Marks WJ, Feiwell R, Aminoff M, Weiner MW. Quantitative 1H magnetic resonance spectroscopy and MRI of Parkinson's disease. Mov Disord. 2002 Sep; 17(5):917-27. PMID: 12360540.
      View in: PubMed
    63. Aminoff M. Electrophysiological evaluation of root and spinal cord disease. Semin Neurol. 2002 Jun; 22(2):197-204. PMID: 12524565.
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    64. Rosenberg RN, Aminoff M, Boller F, Soerensen PS, Griggs RC, Hachinski V, Hallett M, Johnson RT, Kennard C, Lang AE, Lees AJ, Lisak R, Newsom-Davis J, Pedley TA, Selzer ME, Zochodne D. Reporting clinical trials: full access to all the data. Brain. 2002 Mar; 125(Pt 3):i-ii. PMID: 11872625.
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    65. Rosenberg RR, Aminoff M, Boller F, Sørensen PS, Griggs RC, Hallett M, Johnson RT, Hachinski V, Kennard C, Lang AE, Lees AJ, Lisak R, Newsom-Davis J, Pedley TA, Selzer ME, Zochodne D. Reporting clinical trials: full access to all the data. Eur J Neurol. 2002 Mar; 9(2):123-4. PMID: 11882052.
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    66. Rosenberg RN, Aminoff M, Boller F, Soerensen PS, Griggs RC, Hachinski V, Hallett M, Johnson RT, Kennard C, Lang AE, Lees AJ, Lisak R, Newsom-Davis J, Pedley TA, Selzer ME, Zochodne D. Reporting clinical trials: full access to all the data. Muscle Nerve. 2002 Feb; 25(2):133-4. PMID: 11870680.
      View in: PubMed
    67. Rosenberg RN, Aminoff M, Boller F, Soerensen PS, Griggs RC, Hachinski V, Hallett M, Johnson RT, Kennard C, Lang AE, Lees AJ, Lisak R, Newsom-Davis J, Pedley TA, Selzer ME, Zochodne D. Reporting clinical trials: full access to all of the data. Arch Neurol. 2002 Jan; 59(1):27-8. PMID: 11790226.
      View in: PubMed
    68. Rosenberg RN, Aminoff M, Boller F, Soerensen PS, Griggs RC, Hallett M, Hachinski V, Johnson RT, Kennard C, Lang AE, Lees AJ, Lisak R, Newsom-Davis J, Pedley TA, Selzer ME, Zochodne D. Reporting clinical trials: full access to all the data. Mov Disord. 2002 Jan; 17(1):3-4. PMID: 11835431.
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