Franciscus Kuypers, PhD

Title(s)Professional Researcher, Pediatrics
SchoolSchool of Medicine
Address35 Medical Center Way, #903D
San Francisco CA 94143
ORCID ORCID Icon0000-0003-0731-1007 Additional info
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    Hogere Technische School, The NetherlandsIng (MS)05/74Chemical Engineering
    University of Utrecht, The NetherlandsDrs05/81Chemistry
    University of Utrecht, The NetherlandsPhD04/85Biochemistry

    Collapse Overview 
    Collapse Overview
    Studies in membrane biology and hemoglobinopathies have been the center of my research at Children’s Hospital Oakland Research Institute since 1985. We have defined several factors and proteins involved in the maintenance of the lipid bilayer organization of red blood cell membranes, and have defined how alterations, in part induced by oxidant stress, lead to pathology in sickle cell disease and thalassemia. My laboratory serves as a central laboratory for the analysis of blood components in translational research studies in hemoglobinopathies, as part of the reference laboratory for hemoglobinopathies in California. Starting 1/1/2021, the RBC lab was integrated in the hematology division at UCSF and continues to provide support for several NIH and industry sponsored research studies and clinical trials. Work with the mechanical engineering department at UC Berkeley has provided novel technology to characterize individual cells in heterogeneous populations. The establishment of the first sibling cord blood program in the US, translated into the invention of a novel and highly efficient way to collect cord blood and subsequent studies that established the human term placenta as a rich source of hematopoietic and multipotent stem cells.

    RBC lab
    The RBC lab at UCSF builds on a decades long experience defining blood physiology in basic, translational and clinical studies. Our highly experienced staff partners with academia and industry to evaluate approaches aimed to improve the quality of life of patients with abnormalities in blood and blood cell physiology.
    The RBC lab provide detailed assessment of
    -Hematology blood cell characteristics
    -Plasma factors including hemostasis and inflammatory determinants
    -RBC Oxygen affinity assessment
    -Hemoglobin and globin HPLC
    -Microcalorimetric protein-protein interactions
    -Flowcytometry and Image Flowcytometry
    -Ektacytometric RBC deformability

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Roxyscan: A Novel Method to Assess Red Blood Cell Resilience to Oxidative Stress in Sickle Cell Disease. Blood. 2023 Nov 28; 142(Supplement 1):2497. Hernandez HC, Traets TM, van Dijk vM, van Solinge vW, Kuypers KF, Rab RM, Van Beers VE, van Wijk vR. .
      View in: Publisher Site   Mentions:
    2. Initial Results in a Phase 1b Trial of PB-04 in Sickle Cell Disease Demonstrate Fetal Hemoglobin Induction, Additive Activity with Hydroxyurea, and Improved Red Blood Cell Sickling Parameters. Blood. 2023 Nov 28; 142(Supplement 1):1148. Kuo KK, Singer SS, Blyden BG, Bronté-Hall BL, Faller FA, Kutlar KA, Kuypers KF, Zaidi ZA, Hines HP, Patel PN, Larkin LS, Al-Samkari AH, Sheth SS, Nouraie NS, Perrine PS. .
      View in: Publisher Site   Mentions:
    3. Assessment of total and unbound cell-free heme in plasma of patients with sickle cell disease. Exp Biol Med (Maywood). 2023 05; 248(10):897-907. Vissa M, Larkin SK, Vichinsky EP, Kuypers FA, Soupene E. PMID: 36941786; PMCID: PMC10484191.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    4. Blood draw site and analytic device influence hemoglobin measurements. PLoS One. 2022; 17(11):e0278350. Killilea DW, Kuypers FA, Larkin SK, Schultz K. PMID: 36449486.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    5. Dual Role of ACBD6 in the Acylation Remodeling of Lipids and Proteins. Biomolecules. 2022 Nov 22; 12(12). Soupene E, Kuypers FA. PMID: 36551154.
      View in: PubMed   Mentions:    Fields:    
    6. The effects of glutamine supplementation on markers of apoptosis and autophagy in sickle cell disease peripheral blood mononuclear cells. Complement Ther Med. 2022 Nov; 70:102856. Walter PB, Hohman LS, Rokeby A, Lum JJ, Hagar R, Lavrisha L, Saulys A, Kuypers FA, Vichinsky E, Morris CR. PMID: 35843474.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsCTClinical Trials
    7. P1495: ETAVOPIVAT TREATMENT FOR UP TO 12 WEEKS IN PATIENTS WITH SICKLE CELL DISEASE IS WELL TOLERATED AND IMPROVES RED BLOOD CELL HEALTH. HemaSphere. 2022 Jun 1; 6(Suppl):1377-1378. Saraf SS, Brown BR, Hagar HR, Idowu IM, Osunkwo OI, Kalfa KT, Kuypers KF, Geib GJ, Schroeder SP, Wu WE, Kelly KP, Telen TM. .
      View in: Publisher Site   Mentions:
    8. Hyperinflammation, apoptosis, and organ damage. Exp Biol Med (Maywood). 2022 07; 247(13):1112-1123. Kuypers FA. PMID: 35475359; PMCID: PMC9335505.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    9. Correction: Requirement of the acyl-CoA carrier ACBD6 in myristoylation of proteins: Activation by ligand binding and protein interaction. PLoS One. 2022; 17(4):e0267678. Soupene E, Schatz UA, Rudnik-Schöneborn S, Kuypers FA. PMID: 35446914; PMCID: PMC9022860.
      View in: PubMed   Mentions: 1     Fields:    
    10. The ektacytometric elongation Index (EI) of erythrocytes, validation of a prognostic, rheological biomarker for patients with sickle cell disease. Eur J Haematol. 2022 May; 108(5):413-422. Franck P, Buijs P, Meenhuis A, Dane M, Postma C, Spaans A, Gijsbertha N, Kuypers FA, Hudig C, Kerkhoffs JL. PMID: 35088912.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. Implications for the metabolic fate of oral glutamine supplementation within plasma and erythrocytes of patients with sickle cell disease: A pharmacokinetics study. Complement Ther Med. 2022 Mar; 64:102803. Morris CR, Kuypers FA, Hagar R, Larkin S, Lavrisha L, Saulys A, Vichinsky EP, Suh JH. PMID: 35032556.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    12. Etavopivat, an Allosteric Activator of Pyruvate Kinase-R, Improves Sickle RBC Functional Health and Survival and Reduces Systemic Markers of Inflammation and Hypercoagulability in Patients with Sickle Cell Disease: An Analysis of Exploratory Studies in a Phase 1 Study. Blood. 2021 Nov 5; 138(Supplement 1):8-8. Kalfa KT, Telen TM, Saraf SS, Brown BR, Giger Seu GK, Larkin LS, Ribadeneira RM, Schroeder SP, Wu WE, Kelly KP, Kuypers KF. .
      View in: Publisher Site   Mentions:
    13. The Effect of Voxelotor on Exercise Capacity of Youths with Sickle Cell Anemia. Blood. 2021 Nov 5; 138(Supplement 1):2045-2045. Phan PV, Caldarera CL, Cortez CA, Wheeler WK, Larkin LS, Park PS, Dulman DR, Briere BN, Lewis LA, Kuypers KF, Hershenson HJ, Yang YE. .
      View in: Publisher Site   Mentions:
    14. Novel, de novo, beta-globin variant with decreased oxygen affinity (HBB:c.317T>A, "Hemoglobin St. George") in a healthy child with low oxygen saturations and anemia. Am J Hematol. 2021 12 01; 96(12):E448-E450. Meznarich JA, Rets A, Agarwal AM, Christensen RD, Reading NS, Kuypers FA, Prchal JT. PMID: 34553403.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Common host variation drives malaria parasite fitness in healthy human red cells. Elife. 2021 09 23; 10. Ebel ER, Kuypers FA, Lin C, Petrov DA, Egan ES. PMID: 34553687; PMCID: PMC8497061.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    16. Secretory phospholipase A2 in SARS-CoV-2 infection and multisystem inflammatory syndrome in children (MIS-C). Exp Biol Med (Maywood). 2021 12; 246(23):2543-2552. Kuypers FA, Rostad CA, Anderson EJ, Chahroudi A, Jaggi P, Wrammert J, Mantus G, Basu R, Harris F, Hanberry B, Camacho-Gonzalez A, Manoranjithan S, Vos M, Brown LA, Morris CR. PMID: 34255566; PMCID: PMC8649422.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    17. Time to rethink haemoglobin threshold guidelines in sickle cell disease. Br J Haematol. 2021 11; 195(4):518-522. Ballas SK, Kuypers FA, Gordeuk VR, Hankins JS, Thompson AA, Vichinsky E. PMID: 34131897; PMCID: PMC9292304.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    18. Stress and corticotropin releasing factor (CRF) promote necrotizing enterocolitis in a formula-fed neonatal rat model. PLoS One. 2021; 16(6):e0246412. Bell RL, Withers GS, Kuypers FA, Stehr W, Bhargava A. PMID: 34111125; PMCID: PMC8191945.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    19. FT-4202, an Allosteric Activator of Pyruvate Kinase-R, Demonstrates Proof of Mechanism and Proof of Concept after a Single Dose and after Multiple Daily Doses in a Phase 1 Study of Patients with Sickle Cell Disease. Blood. 2020 Nov 5; 136(Supplement 1):19-20. Brown BR, Cruz CK, Kalfa KT, Kuypers KF, Saraf SS, Estepp EJ, Smart SL, Malik MP, Lerman LM, Mayer MR, Ribadeneira RM, Forsyth FS, Schroeder SP, Wu WE, Kelly KP, Telen TM. .
      View in: Publisher Site   Mentions:
    20. Differential Acetone Extraction of Total and Hemoprotein-Unbound Heme to Quantify Heme Binding Capacity of Plasma in Patients with Sickle Cell Disease: The Role of Heme Scavengers. Blood. 2020 Nov 5; 136(Supplement 1):15-15. Vissa VM, Soupene SE, Larkin LS, Neumayr NL, Vichinsky VE, Kuypers KF. .
      View in: Publisher Site   Mentions:
    21. Requirement of the acyl-CoA carrier ACBD6 in myristoylation of proteins: Activation by ligand binding and protein interaction. PLoS One. 2020; 15(2):e0229718. Soupene E, Schatz UA, Rudnik-Schöneborn S, Kuypers FA. PMID: 32108178; PMCID: PMC7046191.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    22. The diversity of ACBD proteins - From lipid binding to protein modulators and organelle tethers. Biochim Biophys Acta Mol Cell Res. 2020 05; 1867(5):118675. Islinger M, Costello JL, Kors S, Soupene E, Levine TP, Kuypers FA, Schrader M. PMID: 32044385; PMCID: PMC7057175.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    23. Phase 1 Single (SAD) and Multiple Ascending Dose (MAD) Studies of the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of FT-4202, an Allosteric Activator of Pyruvate Kinase-R, in Healthy and Sickle Cell Disease Subjects. Blood. 2019 Nov 13; 134(Supplement_1):616-616. Kalfa KT, Kuypers KF, Telen TM, Malik MP, Konstantinidis KD, Estepp EJ, Kim KH, Saraf SS, Wilson WL, Ribadeneira RM, Forsyth FS, Schroeder SP, Drake DA, Polyanskaya PO, Kelly KP, Biernat BL. .
      View in: Publisher Site   Mentions:
    24. Vincristine-induced anemia in hereditary spherocytosis. Exp Biol Med (Maywood). 2019 07; 244(10):850-854. Michlitsch J, Larkin S, Vichinsky E, Kuypers FA. PMID: 31161774; PMCID: PMC6643194.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    25. Image-Based Flow Cytometry and Angle-Resolved Light Scattering to Define the Sickling Process. Cytometry A. 2019 05; 95(5):488-498. Goktas P, Sukharevsky IO, Larkin S, Kuypers FA, Yalcin O, Altintas A. PMID: 30980696.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    26. ACBD6 protein controls acyl chain availability and specificity of the N-myristoylation modification of proteins. J Lipid Res. 2019 03; 60(3):624-635. Soupene E, Kuypers FA. PMID: 30642881; PMCID: PMC6399508.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    27. Hereditary elliptocytosis: Variable clinical severity caused by 3 variants in the α-spectrin gene. Int J Lab Hematol. 2018 08; 40(4):e66-e70. Franck P, Postma C, Spaans A, Veuger M, de Kort G, Hudig C, Wijermans P, Kuypers F. PMID: 29729090.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    28. Phosphatidylserine decarboxylase CT699, lysophospholipid acyltransferase CT775, and acyl-ACP synthase CT776 provide membrane lipid diversity to Chlamydia trachomatis. Sci Rep. 2017 11 17; 7(1):15767. Soupene E, Kuypers FA. PMID: 29150677; PMCID: PMC5693948.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    29. Erythrocytes from hereditary xerocytosis patients heterozygous for KCNN4 V282M exhibit increased spontaneous Gardos channel-like activity inhibited by senicapoc. Am J Hematol. 2017 06; 92(6):E108-E110. Rivera A, Vandorpe DH, Shmukler BE, Gallagher DR, Fikry CC, Kuypers FA, Brugnara C, Snyder LM, Alper SL. PMID: 28295477.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    30. Featured Article: Depletion of HDL3 high density lipoprotein and altered functionality of HDL2 in blood from sickle cell patients. Exp Biol Med (Maywood). 2017 06; 242(12):1244-1253. Soupene E, Larkin SK, Kuypers FA. PMID: 28436274; PMCID: PMC5476340.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    31. Simvastatin reduces vaso-occlusive pain in sickle cell anaemia: a pilot efficacy trial. Br J Haematol. 2017 05; 177(4):620-629. Hoppe C, Jacob E, Styles L, Kuypers F, Larkin S, Vichinsky E. PMID: 28369718; PMCID: PMC5435522.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCTClinical Trials
    32. Interim Results from a Phase 1/2 Clinical Study of Lentiglobin Gene Therapy for Severe Sickle Cell Disease. Blood. 2016 Dec 2; 128(22):1176-1176. Kanter KJ, Walters WM, Hsieh HM, Krishnamurti KL, Kwiatkowski KJ, Kamble KR, von Kalle vC, Kuypers KF, Cavazzana CM, Leboulch LP, Joseney-Antoine JM, Asmal AM, Thompson TA, Tisdale TJ. .
      View in: Publisher Site   Mentions:
    33. Targeting tumor hypoxia with the epigenetic anticancer agent, RRx-001: a superagonist of nitric oxide generation. Med Oncol. 2016 Aug; 33(8):85. Fens MH, Cabrales P, Scicinski J, Larkin SK, Suh JH, Kuypers FA, Oronsky N, Lybeck M, Oronsky A, Oronsky B. PMID: 27377482.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    34. Featured Article: Alterations of lecithin cholesterol acyltransferase activity and apolipoprotein A-I functionality in human sickle blood. Exp Biol Med (Maywood). 2016 11; 241(17):1933-1942. Soupene E, Borja MS, Borda M, Larkin SK, Kuypers FA. PMID: 27354333; PMCID: PMC5068458.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    35. A look inside the mechanistic black box: Are red blood cells the critical effectors of RRx-001 cytotoxicity? Med Oncol. 2016 Jul; 33(7):63. Cabrales P, Scicinski J, Reid T, Kuypers F, Larkin S, Fens M, Oronsky A, Oronsky B. PMID: 27229330.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    36. Simvastatin Reduces Frequency of Vaso-Occlusive Pain in Sickle Cell Disease: A Pilot Efficacy Trial. Blood. 2015 Dec 3; 126(23):545-545. Hoppe HC, Jacob JE, Kuypers KF, Styles SL. .
      View in: Publisher Site   Mentions:
    37. Outcomes of Gene Therapy for Severe Sickle Disease and Beta-Thalassemia Major Via Transplantation of Autologous Hematopoietic Stem Cells Transduced Ex Vivo with a Lentiviral Beta AT87Q-Globin Vector. Blood. 2015 Dec 3; 126(23):202-202. Cavazzana CM, Ribeil RJ, Payen PE, Suarez SF, Beuzard BY, Touzot TF, Cavallesco CR, Lefrere LF, Chretien CS, Bourget BP, Monpoux MF, Pondarre PC, Neven NB, Schmidt SM, von Kalle vC, Kuypers KF, Sandler SL, Soni SS, Hermine HO, Blanche BS, De Montalembert DM, Hacien-Bey-Abina HS, Leboulch LP. .
      View in: Publisher Site   Mentions:
    38. Initial Results from Study Hgb-206: A Phase 1 Study Evaluating Gene Therapy By Transplantation of Autologous CD34+ Stem Cells Transduced Ex Vivo with the Lentiglobin BB305 Lentiviral Vector in Subjects with Severe Sickle Cell Disease. Blood. 2015 Dec 3; 126(23):3233-3233. Kanter KJ, Walters WM, Hsieh HM, Thompson TA, Krishnamurti KL, Kwiatkowski KJ, Kamble KR, von Kalle vC, Kuypers KF, Cavazzana CM, Leboulch LP, Sandler SL, Soni SS, Tisdale TJ. .
      View in: Publisher Site   Mentions:
    39. Sub-population analysis of deformability distribution in heterogeneous red blood cell population. Biomed Microdevices. 2015 Dec; 17(6):102. Lee DW, Doh I, Kuypers FA, Cho YH. PMID: 26383009.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    40. Association of NMT2 with the acyl-CoA carrier ACBD6 protects the N-myristoyltransferase reaction from palmitoyl-CoA. J Lipid Res. 2016 Feb; 57(2):288-98. Soupene E, Kao J, Cheng DH, Wang D, Greninger AL, Knudsen GM, DeRisi JL, Kuypers FA. PMID: 26621918; PMCID: PMC4727424.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    41. Ligand binding to the ACBD6 protein regulates the acyl-CoA transferase reactions in membranes. J Lipid Res. 2015 Oct; 56(10):1961-71. Soupene E, Kuypers FA. PMID: 26290611; PMCID: PMC4583085.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    42. From METS to malaria: RRx-001, a multi-faceted anticancer agent with activity in cerebral malaria. Malar J. 2015 May 28; 14:218. Yalcin O, Oronsky B, Carvalho LJ, Kuypers FA, Scicinski J, Cabrales P. PMID: 26017006; PMCID: PMC4453052.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    43. Dysregulated arginine metabolism and cardiopulmonary dysfunction in patients with thalassaemia. Br J Haematol. 2015 Jun; 169(6):887-98. Morris CR, Kim HY, Klings ES, Wood J, Porter JB, Trachtenberg F, Sweeters N, Olivieri NF, Kwiatkowski JL, Virzi L, Hassell K, Taher A, Neufeld EJ, Thompson AA, Larkin S, Suh JH, Vichinsky EP, Kuypers FA, Thalassemia Clinical Research Network. PMID: 25907665; PMCID: PMC4452408.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    44. Inability to maintain GSH pool in G6PD-deficient red cells causes futile AMPK activation and irreversible metabolic disturbance. Antioxid Redox Signal. 2015 Mar 20; 22(9):744-59. Tang HY, Ho HY, Wu PR, Chen SH, Kuypers FA, Cheng ML, Chiu DT. PMID: 25556665; PMCID: PMC4361223.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    45. Remodeling of host phosphatidylcholine by Chlamydia acyltransferase is regulated by acyl-CoA binding protein ACBD6 associated with lipid droplets. Microbiologyopen. 2015 Apr; 4(2):235-251. Soupene E, Wang D, Kuypers FA. PMID: 25604091; PMCID: PMC4398506.
      View in: PubMed   Mentions: 18     Fields:    
    46. Pan-Selectin Antagonist Rivipansel (GMI-1070) Reduces Soluble E-Selectin Levels While Improving Clinical Outcomes in SCD Vaso-Occlusive Crisis. Blood. 2014 Dec 6; 124(21):2704-2704. Wun WT, Telen TM, Krishnamurti KL, McCavit MT, DeCastro DL, Flanner FH, Kuypers KF, Larkin LS, Rhee RS, Magnani MJ, Thackray TH. .
      View in: Publisher Site   Mentions:
    47. Microparticles as biomarkers of osteonecrosis of the hip in sickle cell disease. Br J Haematol. 2015 Jan; 168(1):135-8. Marsh A, Schiffelers R, Kuypers F, Larkin S, Gildengorin G, van Solinge W, Hoppe C. PMID: 25196812; PMCID: PMC4262623.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    48. The capacity of red blood cells to reduce nitrite determines nitric oxide generation under hypoxic conditions. PLoS One. 2014; 9(7):e101626. Fens MH, Larkin SK, Oronsky B, Scicinski J, Morris CR, Kuypers FA. PMID: 25007272; PMCID: PMC4090171.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    49. Phase 1 study of the E-selectin inhibitor GMI 1070 in patients with sickle cell anemia. PLoS One. 2014; 9(7):e101301. Wun T, Styles L, DeCastro L, Telen MJ, Kuypers F, Cheung A, Kramer W, Flanner H, Rhee S, Magnani JL, Thackray H. PMID: 24988449; PMCID: PMC4079300.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCellsCTClinical Trials
    50. Elevated tricuspid regurgitant jet velocity in subgroups of thalassemia patients: insight into pathophysiology and the effect of splenectomy. Ann Hematol. 2014 Jul; 93(7):1139-48. Singer ST, Kuypers F, Fineman J, Gildengorin G, Larkin S, Sweeters N, Rosenfeld H, Kurio G, Higa A, Jeng M, Huang J, Vichinsky EP. PMID: 24577514; PMCID: PMC4467727.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    51. Thiol/redox metabolomic profiling implicates GSH dysregulation in early experimental graft versus host disease (GVHD). PLoS One. 2014; 9(2):e88868. Suh JH, Kanathezhath B, Shenvi S, Guo H, Zhou A, Tiwana A, Kuypers F, Ames BN, Walters MC. PMID: 24558439; PMCID: PMC3928313.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    52. Hemoglobin s polymerization and red cell membrane changes. Hematol Oncol Clin North Am. 2014 Apr; 28(2):155-79. Kuypers FA. PMID: 24589260.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    53. Microparticles As Biomarkers Of Osteonecrosis Of The Hip In Sickle Cell Disease. Blood. 2013 Nov 15; 122(21):2226-2226. Marsh MA, Schiffelers SR, Gildengorin GG, Kuypers KF, Hoppe HC. .
      View in: Publisher Site   Mentions:
    54. Citrate Synthase Activity Is Increased In Children With Sickle Cell Disease (SCD) On Hydroxyurea (HU) Therapy. Blood. 2013 Nov 15; 122(21):4690-4690. Morris MC, Latronica LC, Kuypers KF, Rosenfeld RH, Larkin LS, Doniger DS, Vichinsky VE, Shiva SS. .
      View in: Publisher Site   Mentions:
    55. RBC deformability and amino acid concentrations after hypo-osmotic challenge may reflect chronic cell hydration status in healthy young men. Physiol Rep. 2013 Oct; 1(5):e00117. Stookey JD, Klein A, Hamer J, Chi C, Higa A, Ng V, Arieff A, Kuypers FA, Larkin S, Perrier E, Lang F. PMID: 24303184; PMCID: PMC3841048.
      View in: PubMed   Mentions: 7     Fields:    
    56. Corticotropin-releasing factor promotes necrotizing enterocolitis in formula fed neonatal rats. Journal of the American College of Surgeons. 2013 Sep 1; 217(3):s80-s81. Bell BR, Bhargava BA, Liao LM, Withers WG, Kuypers KF, Stehr SW. .
      View in: Publisher Site   Mentions:
    57. A randomized, placebo-controlled trial of arginine therapy for the treatment of children with sickle cell disease hospitalized with vaso-occlusive pain episodes. Haematologica. 2013 Sep; 98(9):1375-82. Morris CR, Kuypers FA, Lavrisha L, Ansari M, Sweeters N, Stewart M, Gildengorin G, Neumayr L, Vichinsky EP. PMID: 23645695; PMCID: PMC3762093.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCTClinical Trials
    58. Sildenafil therapy in thalassemia patients with Doppler-defined risk of pulmonary hypertension. Haematologica. 2013 Sep; 98(9):1359-67. Morris CR, Kim HY, Wood J, Porter JB, Klings ES, Trachtenberg FL, Sweeters N, Olivieri NF, Kwiatkowski JL, Virzi L, Singer ST, Taher A, Neufeld EJ, Thompson AA, Sachdev V, Larkin S, Suh JH, Kuypers FA, Vichinsky EP, Thalassemia Clinical Research Network. PMID: 23585527; PMCID: PMC3762091.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    59. Flow-lysometry for cytoplasmic analysis of single cells in large populations. Micro & Nano Letters. 2013 Apr 1; 8(4):169-172. Lee LW, Pisano PA, Cho CY, Kuypers KF. .
      View in: Publisher Site   Mentions:
    60. Treatment with a Novel Dinitroazetidine, Abdnaz, Improves Nitrite Reductase Activity of Sickle Red Blood Cells. Blood. 2012 Nov 16; 120(21):3246-3246. Fens FM, Larkin LS, Fitch FW, Scicinski SJ, Oronsky OB, Kuypers KF. .
      View in: Publisher Site   Mentions:
    61. Tricuspid Regurgitant Jet Velocity (TRV), Biomarkers of Hemolysis, and Impact of Oxygen Therapy in Children with Sickle Cell Disease (SCD) and Vaso-Occlusive Pain Episodes (VOE). Blood. 2012 Nov 16; 120(21):4752-4752. Latronica LC, Kuypers KF, Rosenfeld RH, Larkin LS, Doniger DS, Vichinsky VE, Morris MC. .
      View in: Publisher Site   Mentions:
    62. Sildenafil Therapy in Patients with Thalassemia and an Elevated Tricuspid Regurgitant Jet Velocity (TRV) On Doppler Echocardiography At Risk for Pulmonary Hypertension: Report From the Thalassemia Clinical Research Network. Blood. 2012 Nov 16; 120(21):1023-1023. Morris MC, Kim KH, Wood WJ, Trachtenberg TF, Klings KE, Porter PJ, Sweeters SN, Olivieri ON, Kwiatkowski KJ, Singer SS, Taher TA, Neufeld NE, Thompson TA, Sachdev SV, Larkin LS, Suh SJ, Kuypers KF, Vichinsky VE. .
      View in: Publisher Site   Mentions:
    63. Cardiopulmonary and Laboratory Profiling of Patients with Thalassemia At Risk for Pulmonary Hypertension: Report From the Thalassemia Clinical Research Network. Blood. 2012 Nov 16; 120(21):2122-2122. Morris MC, Kim KH, Wood WJ, Trachtenberg TF, Klings KE, Porter PJ, Sweeters SN, Olivieri ON, Kwiatkowski KJ, Singer SS, Taher TA, Neufeld NE, Thompson TA, Larkin LS, Suh SJ, Vichinsky VE, Kuypers KF. .
      View in: Publisher Site   Mentions:
    64. Pan-Selectin Antagonist GMI-1070 Affects Biomarkers of Adhesion, Activation and the Coagulation Cascade in Sickle Cell Adults At Steady State. Blood. 2012 Nov 16; 120(21):87-87. Magnani MJ, Kuypers KF, Patton PJ, Larkin LS, Styles SL, DeCastro DL, Telen TM, Wun WT, Thackray TH. .
      View in: Publisher Site   Mentions:
    65. Compromised mitochondrial fatty acid synthesis in transgenic mice results in defective protein lipoylation and energy disequilibrium. PLoS One. 2012; 7(10):e47196. Smith S, Witkowski A, Moghul A, Yoshinaga Y, Nefedov M, de Jong P, Feng D, Fong L, Tu Y, Hu Y, Young SG, Pham T, Cheung C, Katzman SM, Brand MD, Quinlan CL, Fens M, Kuypers F, Misquitta S, Griffey SM, Tran S, Gharib A, Knudsen J, Hannibal-Bach HK, Wang G, Larkin S, Thweatt J, Pasta S. PMID: 23077570; PMCID: PMC3471957.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    66. Phosphatidylcholine formation by LPCAT1 is regulated by Ca(2+) and the redox status of the cell. BMC Biochem. 2012 Jun 07; 13:8. Soupene E, Kuypers FA. PMID: 22676268; PMCID: PMC3439698.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    67. Eukaryotic protein recruitment into the Chlamydia inclusion: implications for survival and growth. PLoS One. 2012; 7(5):e36843. Soupene E, Rothschild J, Kuypers FA, Dean D. PMID: 22590624; PMCID: PMC3348897.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    68. Multipotent stromal stem cells from human placenta demonstrate high therapeutic potential. Stem Cells Transl Med. 2012 May; 1(5):359-72. Nazarov I, Lee JW, Soupene E, Etemad S, Knapik D, Green W, Bashkirova E, Fang X, Matthay MA, Kuypers FA, Serikov VB. PMID: 23197815; PMCID: PMC3635148.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    69. Deformation measurement of individual cells in large populations using a single-cell microchamber array chip. Appl Phys Lett. 2012 Apr 23; 100(17):173702-1737023. Doh I, Lee WC, Cho YH, Pisano AP, Kuypers FA. PMID: 22586355; PMCID: PMC3350534.
      View in: PubMed   Mentions: 12  
    70. Changes in cell hydration and amino acid efflux related to chronically higher water intake in healthy young men. The FASEB Journal. 2012 Apr 1; 26(S1):646.22-646.22. Stookey SJ, Klein KA, Hamer HJ, Chi CC, Higa HA, Ng NV, Kuypers KF, Lang LF. .
      View in: Publisher Site   Mentions:
    71. Research in athletes with sickle cell trait: just do it. J Appl Physiol (1985). 2012 May; 112(9):1433. Kuypers FA, Marsh AM. PMID: 22362400.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    72. Systemic and Hepatic Thiol Redox Dysregulation in Graft Versus Host Disease. Transplantation and Cellular Therapy. 2012 Feb 1; 18(2):s359-s360. Kanathezhath KB, Shenvi SS, Johl JA, Manmohan MR, Bhandhal BM, Oh OD, Zhou ZA, Kuypers KF, Walters WM, Ames AB, Suh SJ. .
      View in: Publisher Site   Mentions:
    73. A transgenic mouse model expressing exclusively human hemoglobin E: indications of a mild oxidative stress. Blood Cells Mol Dis. 2012 Feb 15; 48(2):91-101. Chen Q, Fabry ME, Rybicki AC, Suzuka SM, Balazs TC, Etzion Z, de Jong K, Akoto EK, Canterino JE, Kaul DK, Kuypers FA, Lefer D, Bouhassira EE, Hirsch RE. PMID: 22260787; PMCID: PMC3310900.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    74. NO or No NO, Increased Reduction of Nitrite to Nitric Oxide by Modified Red Blood Cells. Blood. 2011 Nov 18; 118(21):2125-2125. Fens FM, Larkin LS, Morris MC, Fitch FB, Scicinski SJ, Oronsky OB, Kuypers KF. .
      View in: Publisher Site   Mentions:
    75. Effect of Short-Term Simvastatin Treatment on Endothelial Adhesion Molecules in Sickle Cell Disease: A Pilot Study. Blood. 2011 Nov 18; 118(21):1070-1070. Hoppe HC, Kuypers KF, Larkin LS, Hagar HR, Vichinsky VE, Styles SL. .
      View in: Publisher Site   Mentions:
    76. A Family with Hereditary Elliptocytosis: Variable Clinical Severity Caused by Three Mutations in the a-Spectrin Gene,. Blood. 2011 Nov 18; 118(21):3167-3167. Franck FP, Postma PC, Veuger VM, Wijermans WP, Kuypers KF. .
      View in: Publisher Site   Mentions:
    77. Phosphatidylserine Exposure in Hemoglobinopathies. Transmembrane Dynamics of Lipids. 2011 Oct 14; 315-340. Kuypers KF, Soupene SE. .
      View in: Publisher Site   Mentions:
    78. Loss-of-function and gain-of-function phenotypes of stomatocytosis mutant RhAG F65S. Am J Physiol Cell Physiol. 2011 Dec; 301(6):C1325-43. Stewart AK, Shmukler BE, Vandorpe DH, Rivera A, Heneghan JF, Li X, Hsu A, Karpatkin M, O'Neill AF, Bauer DE, Heeney MM, John K, Kuypers FA, Gallagher PG, Lux SE, Brugnara C, Westhoff CM, Alper SL. PMID: 21849667; PMCID: PMC3233792.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    79. Tapered oral dexamethasone for the acute chest syndrome of sickle cell disease. Br J Haematol. 2011 Oct; 155(2):263-7. Quinn CT, Stuart MJ, Kesler K, Ataga KI, Wang WC, Styles L, Smith-Whitley K, Wun T, Raj A, Hsu LL, Krishnan S, Kuypers FA, Setty Y, Rhee S, Key NS, Buchanan GR, Investigators of the Comprehensive Sickle Cell Centers. PMID: 21848879; PMCID: PMC3368951.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    80. A pilot study of subcutaneous decitabine in β-thalassemia intermedia. Blood. 2011 Sep 08; 118(10):2708-11. Olivieri NF, Saunthararajah Y, Thayalasuthan V, Kwiatkowski J, Ware RE, Kuypers FA, Kim HY, Trachtenberg FL, Vichinsky EP, Thalassemia Clinical Research Network. PMID: 21700776; PMCID: PMC3172790.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    81. A pilot study of the short-term use of simvastatin in sickle cell disease: effects on markers of vascular dysfunction. Br J Haematol. 2011 Jun; 153(5):655-63. Hoppe C, Kuypers F, Larkin S, Hagar W, Vichinsky E, Styles L. PMID: 21477202; PMCID: PMC3601917.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCTClinical Trials
    82. Improved engraftment with minimal graft-versus-host disease after major histocompatibility complex-mismatched cord blood transplantation with photochemically treated donor lymphocytes. Exp Biol Med (Maywood). 2011 Apr 01; 236(4):492-504. Kanathezhath B, Mizokami M, Stanislaus S, Hounshell C, Neumayr L, Guo H, Hearst JE, Walters MC, Kuypers FA. PMID: 21454375.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    83. Inhibition Of Scramblase-1 Attenuates Endothelial Fluid Loss During Ischemia Reperfusion Injury. Journal of Surgical Research. 2011 Feb 1; 165(2):320. Strumwasser SA, Cureton CE, Cripps CM, Miraflor ME, Yeung YL, Curran CB, Sadjadi SJ, Larkin LS, Kuypers KF, Victorino VG. .
      View in: Publisher Site   Mentions:
    84. Augmented Regulatory T Cell Response After Photochemical Treatment Alleviates Acute Graft-Versus Host Disease and Improves Survival. Transplantation and Cellular Therapy. 2011 Feb 1; 17(2):s331-s332. Kanathezhath KB, Stanislaus SS, Kaplan KJ, Larkin LS, Kuypers KF, Walters WM. .
      View in: Publisher Site   Mentions:
    85. The Effect of Thalassemia and Other RBC Hemolytic Disorders and Splenectomy on the Frequency of Pulmonary Hypertension. Blood. 2010 Nov 19; 116(21):2077-2077. Singer SS, Kuypers KF, Fineman FJ, Larkin LS, Jeng JM, Harmon HC, Sweeters SN, Higa HA, Vichinsky VE. .
      View in: Publisher Site   Mentions:
    86. Metabolic Fate of Oral Glutamine Supplementation within Plasma and Erythrocytes of Patients with Sickle Cell Disease: Preliminary Pharmacokinetics Results. Blood. 2010 Nov 19; 116(21):1636-1636. Morris MC, Kuypers KF, Hagar HR, Ansari AM, Larkin LS, Lavrisha LL, Wardlaw WM, Zhou ZA, Vichinsky VE, Suh SJ. .
      View in: Publisher Site   Mentions:
    87. Augmented Regulatory T Cell Response After Photochemical Treatment Alleviates Acute Graft-Versus-Host Disease and Improves Survival. Blood. 2010 Nov 19; 116(21):3740-3740. Kanathezhath KB, Larkin LS, Kaplan KJ, Walters WM, Kuypers KF. .
      View in: Publisher Site   Mentions:
    88. Effects of Selectin Antagonist GMI-1070 on the Activation State of Leukocytes In Sickle Cell Patients Not In Crisis. Blood. 2010 Nov 19; 116(21):2672-2672. Simon SS, Chase CS, Larkin LS, Kuypers KF, Styles SL, Wun WT, Thackray TH, Magnani MJ. .
      View in: Publisher Site   Mentions:
    89. Estimation of red blood cell volume fraction from overall permittivity measurements. International Journal of Engineering Science. 2010 Nov 1; 48(11):1681-1691. Zohdi ZT, Kuypers KF, Lee LW. .
      View in: Publisher Site   Mentions:
    90. Large-scale arrays of picolitre chambers for single-cell analysis of large cell populations. Lab Chip. 2010 Nov 07; 10(21):2952-8. Lee WC, Rigante S, Pisano AP, Kuypers FA. PMID: 20838671.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    91. Secretory phospholipase A2: a marker of infection in febrile children presenting to a pediatric ED. Am J Emerg Med. 2011 Nov; 29(9):1163-8. Mansour KM, Kuypers FA, Wang TN, Miller AM, Larkin SK, Morris CR. PMID: 20708879; PMCID: PMC3601899.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    92. Tropomodulin 1-null mice have a mild spherocytic elliptocytosis with appearance of tropomodulin 3 in red blood cells and disruption of the membrane skeleton. Blood. 2010 Oct 07; 116(14):2590-9. Moyer JD, Nowak RB, Kim NE, Larkin SK, Peters LL, Hartwig J, Kuypers FA, Fowler VM. PMID: 20585041; PMCID: PMC2953891.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    93. Activity of the acyl-CoA synthetase ACSL6 isoforms: role of the fatty acid Gate-domains. BMC Biochem. 2010 Apr 29; 11:18. Soupene E, Dinh NP, Siliakus M, Kuypers FA. PMID: 20429931; PMCID: PMC2868784.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    94. Hemoglobin Hakkari: an autosomal dominant form of beta thalassemia with inclusion bodies arising from de novo mutation in exon 2 of beta globin gene. Pediatr Blood Cancer. 2010 Feb; 54(2):332-5. Kanathezhath B, Hazard FK, Guo H, Kidd J, Azimi M, Kuypers FA, Vichinsky EP, Lal A. PMID: 19852066.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    95. Augmentation Of Hematopoietic Engraftment Without Graft Versus Host Disease By “Add-Back” Of Photochemically Treated T Lymphocytes In Mismatched Cord Blood Transplantation. Biology of Blood and Marrow Transplantation. 2010 Feb 1; 16(2):s160-s161. Kanathezhath KB, Neumayr NL, Guo GH, Walters WM, Kuypers KF. .
      View in: Publisher Site   Mentions:
    96. The effects of disruption of genes for peroxiredoxin-2, glutathione peroxidase-1, and catalase on erythrocyte oxidative metabolism. Free Radic Biol Med. 2010 Feb 15; 48(4):519-25. Johnson RM, Ho YS, Yu DY, Kuypers FA, Ravindranath Y, Goyette GW. PMID: 19969073; PMCID: PMC2818700.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    97. Arginine Therapy for Vaso-Occlusive Pain Episodes in Sickle Cell Disease. Blood. 2009 Nov 20; 114(22):573-573. Morris MC, Ansari AM, Lavrisha LL, Sweeters SN, Kuypers KF, Vichinsky VE. .
      View in: Publisher Site   Mentions:
    98. The Effect of Short-Term Simvastatin On Markers of Vascular Dysfunction in Patients with Sickle Cell Disease (SCD). Blood. 2009 Nov 20; 114(22):260-260. Hoppe HC, Stewart SK, Higa HA, Larkin LS, Liao LJ, Styles SL, Vichinsky VE, Kuypers KF. .
      View in: Publisher Site   Mentions:
    99. A Pilot Study of Tapered Oral Dexamethasone for the Acute Chest Syndrome of Sickle Cell Disease. Blood. 2009 Nov 20; 114(22):1515-1515. Quinn QC, Stuart SM, Kesler KK, Ataga AK, Wang WW, Styles SL, Smith-Whitley SK, Wun WT, Krishnan KS, Kuypers KF, Setty SY, Key KN, Rhee RS, Buchanan BG. .
      View in: Publisher Site   Mentions:
    100. Improved Engraftment without Graft-Versus-Host Disease After MHC-Mismatched Cord Blood Transplantation with Photochemically Treated Donor Lymphocytes. Blood. 2009 Nov 20; 114(22):2425-2425. Kanathezhath KB, Mizokami MM, Neumayr NL, Guo GH, Walters WM, Kuypers KF. .
      View in: Publisher Site   Mentions:
    101. Human term placenta as a source of hematopoietic cells. Exp Biol Med (Maywood). 2009 Jul; 234(7):813-23. Serikov V, Hounshell C, Larkin S, Green W, Ikeda H, Walters MC, Kuypers FA. PMID: 19429852; PMCID: PMC3389511.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    102. Imaging of the diffusion of single band 3 molecules on normal and mutant erythrocytes. Blood. 2009 Jun 11; 113(24):6237-45. Kodippili GC, Spector J, Sullivan C, Kuypers FA, Labotka R, Gallagher PG, Ritchie K, Low PS. PMID: 19369229; PMCID: PMC2699255.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    103. Erratum: Corrigendum: VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis. Nature Medicine. 2009 Apr 1; 15(4):462-462. Tam TB, Wei WK, Rudge RJ, Hoffman HJ, Holash HJ, Park PS, Yuan YJ, Hefner HC, Chartier CC, Lee LJ, Jiang JS, Nayak NN, Kuypers KF, Ma ML, Sundram SU, Wu WG, Garcia GJ, Schrier SS, Maher MJ, Johnson JR, Yancopoulos YG, Mulligan MR, Kuo KC. .
      View in: Publisher Site   Mentions:
    104. 108. Mobilization of Phosphatidyl Serine to the Outer Endothelial Cell Membrane Regulates Microvascular Fluid Leak During Ischemia-Reperfusion. Journal of Surgical Research. 2009 Feb 1; 151(2):220. Cureton CE, Dozier DK, Kwan KR, Sadjadi SJ, Curran CB, Bhargava BA, Kuypers KF, Victorino VG. .
      View in: Publisher Site   Mentions:
    105. Aldosterone Promotes Inflammation and Endothelial Cell-Sickle Cell Adhesion: Potential for a New Therapeutic Target in Sickle Cell Disease. Blood. 2008 Nov 16; 112(11):125-125. Lam LW, Hansen HW, Huang HJ, Mentzer MW, Lubin LB, Kuypers KF, Fletcher FD. .
      View in: Publisher Site   Mentions:
    106. Red cell membrane lipids in hemoglobinopathies. Curr Mol Med. 2008 Nov; 8(7):633-8. Kuypers FA. PMID: 18991649.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    107. Hydroxycarbamide-induced changes in E/beta thalassemia red blood cells. Am J Hematol. 2008 Nov; 83(11):842-5. Singer ST, Vichinsky EP, Larkin S, Olivieri N, Sweeters N, Kuypers FA, E/beta Thalassemia Study Group. PMID: 18821710; PMCID: PMC2881160.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    108. Lysophosphatidic acid formation in old packed red blood cells causes post transfusion vascular leak. Journal of the American College of Surgeons. 2008 Sep 1; 207(3):s37. Cripps CM, Ereso EA, Victorino VG, Harken HA, Soupene SE, Kuypers KF. .
      View in: Publisher Site   Mentions:
    109. Mammalian long-chain acyl-CoA synthetases. Exp Biol Med (Maywood). 2008 May; 233(5):507-21. Soupene E, Kuypers FA. PMID: 18375835; PMCID: PMC3377585.
      View in: PubMed   Mentions: 172     Fields:    Translation:HumansAnimalsCells
    110. Characterization of an acyl-coenzyme A binding protein predominantly expressed in human primitive progenitor cells. J Lipid Res. 2008 May; 49(5):1103-12. Soupene E, Serikov V, Kuypers FA. PMID: 18268358; PMCID: PMC2311440.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    111. QS386. Lysophosphatidic Acid Levels Increase in Stored Red Blood Cells. Journal of Surgical Research. 2008 Feb 1; 144(2):421. Cripps CM, Soupene SE, Kuypers KF. .
      View in: Publisher Site   Mentions:
    112. ATP8A1 activity and phosphatidylserine transbilayer movement. J Receptor Ligand Channel Res. 2008; 1:1-10. Soupene E, Kemaladewi DU, Kuypers FA. PMID: 20224745; PMCID: PMC2835971.
      View in: PubMed   Mentions: 18  
    113. Mammalian acyl-CoA:lysophosphatidylcholine acyltransferase enzymes. Proc Natl Acad Sci U S A. 2008 Jan 08; 105(1):88-93. Soupene E, Fyrst H, Kuypers FA. PMID: 18156367; PMCID: PMC2224237.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    114. Low Erythrocyte Glutamine-to-Glutamate Ratio: A Novel Biomarker of Hemolysis and Pulmonary Hypertension in Sickle Cell Disease. Blood. 2007 Nov 16; 110(11):2257-2257. Morris MC, Suh SJ, Hagar HW, Larkin LS, Bland BD, Steinberg SM, Vichinsky VE, Shigenaga SM, Ames AB, Kuypers KF, Klings KE. .
      View in: Publisher Site   Mentions:
    115. Phospholipase D Activity Is Essential for PKC-Mediated Phosphatidylserine Exposure. Blood. 2007 Nov 16; 110(11):1715-1715. DeJong DK, Rahbar RS, Kuypers KF. .
      View in: Publisher Site   Mentions:
    116. Oxidative Metabolism in Red Cells Deficient in Antioxidant Enzymes. Blood. 2007 Nov 16; 110(11):1716-1716. Johnson JR, Ho HY, Yu YD, Kuypers KF, Ravindranath RY, Goyette GG. .
      View in: Publisher Site   Mentions:
    117. Insight into Risk Factors for Pulmonary Hypertension in Thalassemia: Abnormal Platelet, Hemolysis and Vascular Markers. Blood. 2007 Nov 16; 110(11):576-576. Singer SS, Kuypers KF, Jeffrey JF, Sandy SL, Cynthia CH, Howard HR, Ann AL, Diane DN, Elliott EV. .
      View in: Publisher Site   Mentions:
    118. Anti-Oxidant Treatment with a-Lipoic Acid and Acetyl L-Carnitine in Hemoglobinopathies. Blood. 2007 Nov 16; 110(11):3799-3799. Lal LA, Suh SJ, Atamna AW, Canty CB, Hagar HW, Vichinsky VE, Kuypers KF, Ames AB. .
      View in: Publisher Site   Mentions:
    119. Enhanced Phosphatidylserine Scrambling in Oxidatively Challenged Red Blood Cells. Blood. 2007 Nov 16; 110(11):1718-1718. DeJong DK, Kuypers KF. .
      View in: Publisher Site   Mentions:
    120. Arginine Therapy Does Not Benefit Children with Sickle Cell Anemia — Results of the CSCC Clinical Trial Consortium Multi-Institutional Study. Blood. 2007 Nov 16; 110(11):2252-2252. Styles SL, Kuypers KF, Kesler KK, Reiss RU, Lebeau LP, Nagel NR, Fabry FM. .
      View in: Publisher Site   Mentions:
    121. Erythrocyte glutamine depletion, altered redox environment, and pulmonary hypertension in sickle cell disease. Blood. 2008 Jan 01; 111(1):402-10. Morris CR, Suh JH, Hagar W, Larkin S, Bland DA, Steinberg MH, Vichinsky EP, Shigenaga M, Ames B, Kuypers FA, Klings ES. PMID: 17848621; PMCID: PMC2200820.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCells
    122. Flow cytometric determination of PMCA-mediated Ca2+-extrusion in individual red blood cells. Cytometry A. 2007 Sep; 71(9):693-9. de Jong K, Kuypers FA. PMID: 17598186.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    123. Erythrocytes contain a membrane lysophosphatidic acid acyltransferase that modulates serum lysophosphatidic acid concentration. Journal of the American College of Surgeons. 2007 Sep 1; 205(3):s34. Cripps CM, Soupene SE, Harken HA, Kuypers KF. .
      View in: Publisher Site   Mentions:
    124. Interaction of an annexin V homodimer (Diannexin) with phosphatidylserine on cell surfaces and consequent antithrombotic activity. Thromb Haemost. 2007 Mar; 97(3):478-86. Kuypers FA, Larkin SK, Emeis JJ, Allison AC. PMID: 17334517.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    125. Membrane lipid alterations in hemoglobinopathies. Hematology Am Soc Hematol Educ Program. 2007; 68-73. Kuypers FA. PMID: 18024611.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    126. Modelling and rapid simulation of multiple red blood cell light scattering. J R Soc Interface. 2006 Dec 22; 3(11):823-31. Zohdi TI, Kuypers FA. PMID: 17015301; PMCID: PMC1885364.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    127. Transfusion prevents acute chest syndrome predicted by elevated secretory phospholipase A2. Br J Haematol. 2007 Jan; 136(2):343-4. Styles LA, Abboud M, Larkin S, Lo M, Kuypers FA. PMID: 17156397.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    128. High Calcium Requirement for Phosphatidylserine Exposure in Sickle Cell Disease. Blood. 2006 Nov 16; 108(11):3788-3788. DeJong DK, Miller MA, Emerson ER, Kuypers KF. .
      View in: Publisher Site   Mentions:
    129. Dysregulation of Phosphatidylserine Scrambling by Oxidative Stress. Blood. 2006 Nov 16; 108(11):1573-1573. DeJong DK, Kuypers KF. .
      View in: Publisher Site   Mentions:
    130. Flippase Activity Decreases throughout Erythrocyte Life-Span in Normal and Sickle Mice. Blood. 2006 Nov 16; 108(11):3786-3786. DeJong DK, Bhagat BA, Emerson ER, Kuypers KF. .
      View in: Publisher Site   Mentions:
    131. Erythrocyte Glutathione Depletion Is Associated with Severity of Anemia and Pulmonary Hypertension in Patients with Sickle Cell Disease. Blood. 2006 Nov 16; 108(11):788-788. Morris MC, Suh SJ, Larkin LS, Bland BD, Odhiambo OA, Steinberg SM, Vichinsky VE, Shigenaga SM, Ames AB, Kuypers KF, Klings KE. .
      View in: Publisher Site   Mentions:
    132. Lysophospholipid Acylation in RBC. Blood. 2006 Nov 16; 108(11):1575-1575. Soupene SE, Kuypers KF. .
      View in: Publisher Site   Mentions:
    133. Acyl-CoA Turnover in RBC. Blood. 2006 Nov 16; 108(11):1579-1579. Soupene SE, Siliakus SM, Kuypers KF. .
      View in: Publisher Site   Mentions:
    134. Pulmonary hypertension in thalassemia: association with platelet activation and hypercoagulable state. Am J Hematol. 2006 Sep; 81(9):670-5. Singer ST, Kuypers FA, Styles L, Vichinsky EP, Foote D, Rosenfeld H. PMID: 16795058.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    135. Multiple erythroid isoforms of human long-chain acyl-CoA synthetases are produced by switch of the fatty acid gate domains. BMC Mol Biol. 2006 Jul 11; 7:21. Soupene E, Kuypers FA. PMID: 16834775; PMCID: PMC1543647.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    136. VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis. Nat Med. 2006 Jul; 12(7):793-800. Tam BY, Wei K, Rudge JS, Hoffman J, Holash J, Park SK, Yuan J, Hefner C, Chartier C, Lee JS, Jiang S, Nayak NR, Niyak NR, Kuypers FA, Ma L, Sundram U, Wu G, Garcia JA, Schrier SL, Maher JJ, Johnson RS, Yancopoulos GD, Mulligan RC, Kuo CJ. PMID: 16799557.
      View in: PubMed   Mentions: 66     Fields:    Translation:Animals
    137. Identification of an erythroid ATP-dependent aminophospholipid transporter. Br J Haematol. 2006 May; 133(4):436-8. Soupene E, Kuypers FA. PMID: 16643453.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    138. Sulphydryl modifications alter scramblase activity in murine sickle cell disease. Br J Haematol. 2006 May; 133(4):427-32. de Jong K, Kuypers FA. PMID: 16643451.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    139. Secretory phospholipase A2 levels in patients with sickle cell disease and acute chest syndrome. Hemoglobin. 2006; 30(2):165-70. Ballas SK, Files B, Luchtman-Jones L, Benjamin L, Swerdlow P, Hilliard L, Coates T, Abboud M, Wojtowicz-Praga S, Kuypers FA, Michael Grindel J. PMID: 16798640.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    140. Multiple Erythroid Isoforms of Human Long-Chain acyl-CoA Synthetases Are Produced by a Switch of the Fatty Acid Gate-Domains. Blood. 2005 Nov 16; 106(11):1672-1672. Soupene SE, Kuypers KF. .
      View in: Publisher Site   Mentions:
    141. Phosphatidylserine Scrambling Is Faster in Sickle Mouse Erythrocytes Because of Oxidative Damage. Blood. 2005 Nov 16; 106(11):2331-2331. DeJong DK, Kuypers KF. .
      View in: Publisher Site   Mentions:
    142. Elevated Plasma Arginase Levels in Hemoglobinopathies. Blood. 2005 Nov 16; 106(11):2346-2346. Larkin LS, Morris MC, Styles SL, Kuypers KF. .
      View in: Publisher Site   Mentions:
    143. Dysregulated Arginine Metabolism and Elevated Arginase Activity in Thalassemia. Blood. 2005 Nov 16; 106(11):3644-3644. Morris MC, Kuypers KF, Kato KG, Gardner GJ, Larkin LS, Singer ST, Vichinsky VE. .
      View in: Publisher Site   Mentions:
    144. A Novel Umbilical Cord Blood Collection System. Blood. 2005 Nov 16; 106(11):5285-5285. Kuypers KF, Atkinson AW, Hounshell HC, Lubin LB, Meyst MR. .
      View in: Publisher Site   Mentions:
    145. A Transgenic Mouse Model of Homozygous HbE Disease. Blood. 2005 Nov 16; 106(11):3192-3192. Chen CQ, Kuypers KF, Rybicki RA, Bhagat BA, Suzuka SS, Fabry FM, Nagel NR, Hirsch HR. .
      View in: Publisher Site   Mentions:
    146. Increased Chromosomal Breaks in Sickle Cell Disease as Evidenced by the Presence of Micronuclei in Erythrocytes. Blood. 2005 Nov 16; 106(11):3807-3807. Lal LA, Bhagat BA, Atamna AW, Offer OT, Vichinsky VE, Kuypers KF, Ames AB. .
      View in: Publisher Site   Mentions:
    147. Hydrolysis of phosphatidylserine-exposing red blood cells by secretory phospholipase A2 generates lysophosphatidic acid and results in vascular dysfunction. J Biol Chem. 2006 Jan 13; 281(2):775-81. Neidlinger NA, Larkin SK, Bhagat A, Victorino GP, Kuypers FA. PMID: 16278219.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    148. Fetal haemoglobin augmentation in E/beta(0) thalassaemia: clinical and haematological outcome. Br J Haematol. 2005 Nov; 131(3):378-88. Singer ST, Kuypers FA, Olivieri NF, Weatherall DJ, Mignacca R, Coates TD, Davies S, Sweeters N, Vichinsky EP, E/beta Thalassaemia Study Group. PMID: 16225658.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    149. Post-traumatic circulating secretory phospholipase A2 lyses cells with exposed phosphatidylserine and causes microvascular fluid leak. Journal of the American College of Surgeons. 2005 Sep 1; 201(3):s29. Neidlinger NN, Larkin LS, Curran CB, Victorino VG, Kuypers KF. .
      View in: Publisher Site   Mentions:
    150. Serum C-reactive protein parallels secretory phospholipase A2 in sickle cell disease patients with vasoocclusive crisis or acute chest syndrome. Blood. 2005 Apr 15; 105(8):3384-5. Bargoma EM, Mitsuyoshi JK, Larkin SK, Styles LA, Kuypers FA, Test ST. PMID: 15802550.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    151. Postinjury serum secretory phospholipase A2 correlates with hypoxemia and clinical status at 72 hours. J Am Coll Surg. 2005 Feb; 200(2):173-8. Neidlinger NA, Hirvela ER, Skinner RA, Larkin SK, Harken AH, Kuypers FA. PMID: 15664090.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    152. Hemolysis-associated pulmonary hypertension in thalassemia. Ann N Y Acad Sci. 2005; 1054:481-5. Morris CR, Kuypers FA, Kato GJ, Lavrisha L, Larkin S, Singer T, Vichinsky EP. PMID: 16339702; PMCID: PMC3217300.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    153. Measuring chromosome breaks in patients with thalassemia. Ann N Y Acad Sci. 2005; 1054:439-44. Offer T, Bhagat A, Lal A, Atamna W, Singer ST, Vichinsky EP, Kuypers FA, Ames BN. PMID: 16339694.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    154. Rescued mice with Hb E transgene-developed red cell changes similar to human beta-thalassemia/HbE disease. Ann N Y Acad Sci. 2005; 1054:407-16. Wannasuphaphol B, Kalpravidh R, Pattanapanyasat K, Ioannau P, Kuypers FA, Fucharoen S, Winichagoon P. PMID: 16339689.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    155. Single and combination drug therapy for fetal hemoglobin augmentation in hemoglobin E-beta 0-thalassemia: Considerations for treatment. Ann N Y Acad Sci. 2005; 1054:250-6. Singer ST, Kuypers FA, Olivieri NF, Weatherall DJ, Mignacca R, Coates TD, Davies S, Sweeters N, Vichinsky EP. PMID: 16339672.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    156. Stem cell transplantation with S-59 photochemically treated T-cell add-backs to establish allochimerism in murine thalassemia. Ann N Y Acad Sci. 2005; 1054:214-22. Kuypers FA, Watson G, Sage E, Walters MC, Hamrick J, Hearst JE. PMID: 16339668.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    157. A simple assay for frequency of chromosome breaks and loss (micronuclei) by flow cytometry of human reticulocytes. FASEB J. 2005 Mar; 19(3):485-7. Offer T, Ho E, Traber MG, Bruno RS, Kuypers FA, Ames BN. PMID: 15601670.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCellsPHPublic Health
    158. Red Blood Cells Facilitate Reverse Cholesterol Transport. Blood. 2004 Nov 16; 104(11):1589-1589. Kuypers KF, Larkin LS, Beckstead BJ, Oda OM, Ueda UK, Ryan RR. .
      View in: Publisher Site   Mentions:
    159. Di-Annexin, a Novel Tool To Identify and Protect Phosphatidylserine Exposing Cells. Blood. 2004 Nov 16; 104(11):1581-1581. Kuypers KF, Larkin LS, Emerson ER, Allison AA. .
      View in: Publisher Site   Mentions:
    160. Biotin-Labeled RBC Survival in Thalassemia and Impact of Treatment. Blood. 2004 Nov 16; 104(11):3616-3616. Singer SS, Olivieri ON, Sweeters SN, Rodwell RC, Oliver OC, Vichinsky VE, Kuypers KF. .
      View in: Publisher Site   Mentions:
    161. Reactive Oxygen Species and RBC Membrane Integrity in Peroxyredoxin II Deficient Mice. Blood. 2004 Nov 16; 104(11):54-54. Bhagat BA, Emerson ER, DeJong DK, Kuypers KF. .
      View in: Publisher Site   Mentions:
    162. Oxidative Modifications to Flippase and Scramblase Affect Phosphatidylserine Exposure in Mouse Sickle Cells. Blood. 2004 Nov 16; 104(11):3752-3752. DeJong DK, Kuypers KF. .
      View in: Publisher Site   Mentions:
    163. In vivo reduction of erythrocyte oxidant stress in a murine model of beta-thalassemia. Haematologica. 2004 Nov; 89(11):1287-98. de Franceschi L, Turrini F, Honczarenko M, Ayi K, Rivera A, Fleming MD, Law T, Mannu F, Kuypers FA, Bast A, van der Vijgh WJ, Brugnara C. PMID: 15531450.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    164. Secretory phospholipase A2 attacks erythrocytes with externalized phosphatidylserine. Journal of Surgical Research. 2004 Oct 1; 121(2):277. Neidlinger NN, Larkin LS, Kuypers KF. .
      View in: Publisher Site   Mentions:
    165. Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family. J Lipid Res. 2004 Oct; 45(10):1958-61. Mashek DG, Bornfeldt KE, Coleman RA, Berger J, Bernlohr DA, Black P, DiRusso CC, Farber SA, Guo W, Hashimoto N, Khodiyar V, Kuypers FA, Maltais LJ, Nebert DW, Renieri A, Schaffer JE, Stahl A, Watkins PA, Vasiliou V, Yamamoto TT. PMID: 15292367.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimals
    166. Decreased arginine bioavailability and increased serum arginase activity in asthma. Am J Respir Crit Care Med. 2004 Jul 15; 170(2):148-53. Morris CR, Poljakovic M, Lavrisha L, Machado L, Kuypers FA, Morris SM. PMID: 15070820.
      View in: PubMed   Mentions: 107     Fields:    Translation:HumansCTClinical Trials
    167. The role of phosphatidylserine in recognition and removal of erythrocytes. Cell Mol Biol (Noisy-le-grand). 2004 Mar; 50(2):147-58. Kuypers FA, de Jong K. PMID: 15095785.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    168. The role of secretory phospholipase A2 in acute chest syndrome. Cell Mol Biol (Noisy-le-grand). 2004 Feb; 50(1):87-94. Kuypers FA, Styles LA. PMID: 15040432.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    169. Reactive oxygen species and phosphatidylserine externalization in murine sickle red cells. Br J Haematol. 2004 Feb; 124(3):391-402. Banerjee T, Kuypers FA. PMID: 14717789.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    170. Hydroxyurea and arginine therapy: impact on nitric oxide production in sickle cell disease. J Pediatr Hematol Oncol. 2003 Aug; 25(8):629-34. Morris CR, Vichinsky EP, van Warmerdam J, Machado L, Kepka-Lenhart D, Morris SM, Kuypers FA. PMID: 12902916.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCTClinical Trials
    171. Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease? Am J Respir Crit Care Med. 2003 Jul 01; 168(1):63-9. Morris CR, Morris SM, Hagar W, Van Warmerdam J, Claster S, Kepka-Lenhart D, Machado L, Kuypers FA, Vichinsky EP. PMID: 12626350.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansCTClinical Trials
    172. Protein kinase C activation induces phosphatidylserine exposure on red blood cells. Biochemistry. 2002 Oct 15; 41(41):12562-7. de Jong K, Rettig MP, Low PS, Kuypers FA. PMID: 12369848.
      View in: PubMed   Mentions:
    173. Altered red cell turnover in diabetic mice. J Lab Clin Med. 2002 Sep; 140(3):161-5. Manodori AB, Kuypers FA. PMID: 12271273.
      View in: PubMed   Mentions:
    174. A 29-kDa protein associated with p67phox expresses both peroxiredoxin and phospholipase A2 activity and enhances superoxide anion production by a cell-free system of NADPH oxidase activity. J Biol Chem. 2002 Nov 22; 277(47):45181-7. Leavey PJ, Gonzalez-Aller C, Thurman G, Kleinberg M, Rinckel L, Ambruso DW, Freeman S, Kuypers FA, Ambruso DR. PMID: 12121978.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    175. Selective increase of autoimmune epitope expression on aged erythrocytes in mice: implications in anti-erythrocyte autoimmune responses. J Autoimmun. 2002 Feb; 18(1):17-25. Fossati-Jimack L, Azeredo da Silveira S, Moll T, Kina T, Kuypers FA, Oldenborg PA, Reininger L, Izui S. PMID: 11869043.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    176. Short survival of phosphatidylserine-exposing red blood cells in murine sickle cell anemia. Blood. 2001 Sep 01; 98(5):1577-84. de Jong K, Emerson RK, Butler J, Bastacky J, Mohandas N, Kuypers FA. PMID: 11520810.
      View in: PubMed   Mentions:
    177. Characterization of the phosphatidylserine-exposing subpopulation of sickle cells. Blood. 2001 Aug 01; 98(3):860-7. de Jong K, Larkin SK, Styles LA, Bookchin RM, Kuypers FA. PMID: 11468189.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    178. Secretory phospholipase A2 activity correlates with postinjury multiple organ failure. Crit Care Med. 2001 May; 29(5):989-93. Partrick DA, Moore EE, Silliman CC, Barnett CC, Kuypers FA. PMID: 11378609.
      View in: PubMed   Mentions:
    179. Absence of mitochondrial superoxide dismutase results in a murine hemolytic anemia responsive to therapy with a catalytic antioxidant. J Exp Med. 2001 Apr 16; 193(8):925-34. Friedman JS, Rebel VI, Derby R, Bell K, Huang TT, Kuypers FA, Epstein CJ, Burakoff SJ. PMID: 11304553; PMCID: PMC2193409.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    180. Reduced oxidative-stress response in red blood cells from p45NFE2-deficient mice. Blood. 2001 Apr 01; 97(7):2151-8. Chan JY, Kwong M, Lo M, Emerson R, Kuypers FA. PMID: 11264184.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    181. Alloimmunization and erythrocyte autoimmunization in transfusion-dependent thalassemia patients of predominantly asian descent. Blood. 2000 Nov 15; 96(10):3369-73. Singer ST, Wu V, Mignacca R, Kuypers FA, Morel P, Vichinsky EP. PMID: 11071629.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansCells
    182. Alloimmunization and erythrocyte autoimmunization in transfusion-dependent thalassemia patients of predominantly Asian descent. Blood. 2000 Nov 15; 96(10):3369-3373. Singer SS, Wu WV, Mignacca MR, Kuypers KF, Morel MP, Vichinsky VE. .
      View in: Publisher Site   Mentions:
    183. Arginine therapy: a novel strategy to induce nitric oxide production in sickle cell disease. British Journal of Haematology. 2000 Nov 1; 111(2):498-500. Morris MC, Kuypers KF, Larkin LS, Sweeters SN, Simon SJ, Vichinsky VE, Styles SL. .
      View in: Publisher Site   Mentions:
    184. Secretory phospholipase A(2) predicts impending acute chest syndrome in sickle cell disease. Blood. 2000 Nov 01; 96(9):3276-8. Styles LA, Aarsman AJ, Vichinsky EP, Kuypers FA. PMID: 11050014.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    185. Patterns of arginine and nitric oxide in patients with sickle cell disease with vaso-occlusive crisis and acute chest syndrome. J Pediatr Hematol Oncol. 2000 Nov-Dec; 22(6):515-20. Morris CR, Kuypers FA, Larkin S, Vichinsky EP, Styles LA. PMID: 11132219.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    186. Arginine therapy: a novel strategy to induce nitric oxide production in sickle cell disease. Br J Haematol. 2000 Nov; 111(2):498-500. Morris CR, Kuypers FA, Larkin S, Sweeters N, Simon J, Vichinsky EP, Styles LA. PMID: 11122090.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    187. Secretory phospholipase A2 predicts impending acute chest syndrome in sickle cell disease. Blood. 2000 Nov 1; 96(9):3276-3278. Styles SL, Aarsman AA, Vichinsky VE, Kuypers KF. .
      View in: Publisher Site   Mentions:
    188. Sera of patients suffering from inflammatory diseases contain group IIA but not group V phospholipase A(2). Biochim Biophys Acta. 2000 Oct 18; 1502(2):257-63. Aarsman AJ, Neys FW, van der Helm HA, Kuypers FA, van den Bosch H. PMID: 11040450.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    189. Adherence of phosphatidylserine-exposing erythrocytes to endothelial matrix thrombospondin. Blood. 2000 Feb 15; 95(4):1293-300. Manodori AB, Barabino GA, Lubin BH, Kuypers FA. PMID: 10666202.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    190. SECRETORY PHOSPHOLIPASE A2: A POTENTIAL MARKER FOR RESPIRATORY FAILURE IN TRAUMA PATIENTS. Critical Care Medicine. 1999 Dec 1; 27(12):a21. Hirvela HE, Skinner SR, Henderson HV, Larkin LS, Styles SL, Kuypers KF. .
      View in: Publisher Site   Mentions:
    191. Identification and molecular characterization of acyl-CoA synthetase in human erythrocytes and erythroid precursors. Biochem J. 1999 Nov 15; 344 Pt 1:135-43. Malhotra KT, Malhotra K, Lubin BH, Kuypers FA. PMID: 10548543; PMCID: PMC1220623.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    192. Identification and molecular characterization of acyl-CoA synthetase in human erythrocytes and erythroid precursors. Biochemical Journal. 1999 Nov 8; 344(1):135-143. MALHOTRA MK, MALHOTRA MK, LUBIN LB, KUYPERS KF. .
      View in: Publisher Site   Mentions:
    193. Hereditary spherocytosis and elliptocytosis erythrocytes show a normal transbilayer phospholipid distribution. Blood. 1999 Jul 01; 94(1):319-25. de Jong K, Larkin SK, Eber S, Franck PF, Roelofsen B, Kuypers FA. PMID: 10381528.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    194. The PLB2 gene of Saccharomyces cerevisiae confers resistance to lysophosphatidylcholine and encodes a phospholipase B/lysophospholipase. Biochemistry. 1999 May 04; 38(18):5864-71. Fyrst H, Oskouian B, Kuypers FA, Saba JD. PMID: 10231538.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    195. Detection of phosphatidylserine surface exposure on human erythrocytes using annexin V-ferrofluid. Biochem Biophys Res Commun. 1999 Apr 29; 258(1):199-203. Geldwerth D, Helley D, de Jong K, Sabolovic' D, Sestier C, Roger J, Pons JN, Freyssinet JM, Devaux PF, Kuypers FA. PMID: 10222260.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    196. Stomatocytosis is absent in "stomatin"-deficient murine red blood cells. Blood. 1999 Apr 01; 93(7):2404-10. Zhu Y, Paszty C, Turetsky T, Tsai S, Kuypers FA, Lee G, Cooper P, Gallagher PG, Stevens ME, Rubin E, Mohandas N, Mentzer WC. PMID: 10090952.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    197. Creation of Chimerism in a Thalassemic Mouse Model. Pediatric Research. 1999 Apr 1; 45(7):151-151. Quesenberry QP, Zhong ZS, Wang WH, Werme WK, Kuypers KF, Watson WG, Lubin LB. .
      View in: Publisher Site   Mentions:
    198. L-Arginine Therapy Paradoxically Decreases Nitric Oxide Production in Patients with Sickle Cell Disease. Pediatric Research. 1999 Apr 1; 45(7):150-150. Morris MC, Kuypers KF, Larkin LS, Kennedy KN, Simon SJ, Vichinsky VE, Styles SL. .
      View in: Publisher Site   Mentions:
    199. Low Molecular Weight Heparin in Sickle Cell Disease. Pediatric Research. 1999 Apr 1; 45(7):153-153. Styles SL, Larkin LS, Kennedy KN, Simon SJ, Kuypers KF, Vichinsky VE. .
      View in: Publisher Site   Mentions:
    200. Stomatocytosis Is Absent in “Stomatin”-Deficient Murine Red Blood Cells. Blood. 1999 Apr 1; 93(7):2404-2410. Zhu ZY, Paszty PC, Turetsky TT, Tsai TS, Kuypers KF, Lee LG, Cooper CP, Gallagher GP, Stevens SM, Rubin RE, Mohandas MN, Mentzer MW. .
      View in: Publisher Site   Mentions:
    201. Structural and functional consequences of antigenic modulation of red blood cells with methoxypoly(ethylene glycol). Blood. 1999 Mar 15; 93(6):2121-7. Murad KL, Mahany KL, Brugnara C, Kuypers FA, Eaton JW, Scott MD. PMID: 10068687.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    202. Red cell membrane damage. J Heart Valve Dis. 1998 Jul; 7(4):387-95. Kuypers FA. PMID: 9697059.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    203. Whole blood tissue factor procoagulant activity is elevated in patients with sickle cell disease. Blood. 1998 Jun 01; 91(11):4216-23. Key NS, Slungaard A, Dandelet L, Nelson SC, Moertel C, Styles LA, Kuypers FA, Bach RR. PMID: 9596669.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    204. Whole Blood Tissue Factor Procoagulant Activity Is Elevated in Patients With Sickle Cell Disease. Blood. 1998 Jun 1; 91(11):4216-4223. Key KN, Slungaard SA, Dandelet DL, Nelson NS, Moertel MC, Styles SL, Kuypers KF, Bach BR. .
      View in: Publisher Site   Mentions:
    205. Membrane phospholipid asymmetry in human thalassemia. Blood. 1998 Apr 15; 91(8):3044-51. Kuypers FA, Yuan J, Lewis RA, Snyder LM, Kiefer CR, Bunyaratvej A, Fucharoen S, Ma L, Styles L, de Jong K, Schrier SL. PMID: 9531618.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    206. Effects of phosphatidylinositol diphosphate on phospholipid asymmetry in the human erythrocyte membrane. Biochemistry. 1998 Mar 10; 37(10):3449-58. Shiffer KA, Rood L, Emerson RK, Kuypers FA. PMID: 9521666.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    207. Phospholipid asymmetry in health and disease. Curr Opin Hematol. 1998 Mar; 5(2):122-31. Kuypers FA. PMID: 9570705.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    208. Removal of erythrocyte membrane iron in vivo ameliorates the pathobiology of murine thalassemia. J Clin Invest. 1997 Sep 15; 100(6):1459-64. Browne PV, Shalev O, Kuypers FA, Brugnara C, Solovey A, Mohandas N, Schrier SL, Hebbel RP. PMID: 9294111; PMCID: PMC508324.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    209. Acyl-CoA binding protein (ACBP) in the human red-cell. Biochemical Journal. 1997 Aug 1; 325(3):811-814. FYRST FH, KUYPERS KF. .
      View in: Publisher Site   Mentions:
    210. Oxidative damage does not alter membrane phospholipid asymmetry in human erythrocytes. Biochemistry. 1997 Jun 03; 36(22):6768-76. de Jong K, Geldwerth D, Kuypers FA. PMID: 9184159.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    211. Decrease of very late activation antigen-4 and CD36 on reticulocytes in sickle cell patients treated with hydroxyurea. Blood. 1997 Apr 01; 89(7):2554-9. Styles LA, Lubin B, Vichinsky E, Lawrence S, Hua M, Test S, Kuypers F. PMID: 9116302.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    212. Phospholipase A2 levels in acute chest syndrome of sickle cell disease. Blood. 1996 Mar 15; 87(6):2573-8. Styles LA, Schalkwijk CG, Aarsman AJ, Vichinsky EP, Lubin BH, Kuypers FA. PMID: 8630425.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    213. Formation of vesicles by the action of acyl-CoA:1-acyllsophosphatidylcholine acyltransferase from rat liver microsomes: optimal solubilization conditions and analysis of lipid composition and enzyme activity. Biochemistry. 1996 Feb 27; 35(8):2644-50. Fyrst H, Pham DV, Lubin BH, Kuypers FA. PMID: 8611569.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    214. Detection of altered membrane phospholipid asymmetry in subpopulations of human red blood cells using fluorescently labeled annexin V. Blood. 1996 Feb 01; 87(3):1179-87. Kuypers FA, Lewis RA, Hua M, Schott MA, Discher D, Ernst JD, Lubin BH. PMID: 8562945.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    215. Correlation of membrane lipid peroxidation with oxidation of hemoglobin variants: possibly related to the rates of hemin release. Free Radic Biol Med. 1996; 21(1):89-95. Chiu DT, van den Berg J, Kuypers FA, Hung IJ, Wei JS, Liu TZ. PMID: 8791096.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    216. Phospholipid composition and organization in model beta-thalassemic erythrocytes. Am J Hematol. 1996 Jan; 51(1):45-54. Kuypers FA, Schott MA, Scott MD. PMID: 8571937.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    217. Effects of bacterial endotoxin on human cross-linked and native hemoglobins. Biochemistry. 1995 Sep 05; 34(35):11176-85. Kaca W, Roth RI, Vandegriff KD, Chen GC, Kuypers FA, Winslow RM, Levin J. PMID: 7669775.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    218. Detection of acyl-CoA-binding protein in human red blood cells and investigation of its role in membrane phospholipid renewal. Biochem J. 1995 Mar 15; 306 ( Pt 3):793-9. Fyrst H, Knudsen J, Schott MA, Lubin BH, Kuypers FA. PMID: 7702576; PMCID: PMC1136591.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    219. Copper and gas-phase cigarette smoke inhibit plasma lecithin:cholesterol acyltransferase activity by different mechanisms. J Lipid Res. 1995 Feb; 36(2):322-31. Bielicki JK, McCall MR, van den Berg JJ, Kuypers FA, Forte TM. PMID: 7751820.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    220. Membrane changes associated with lysis of red blood cells by hypochlorous acid. Free Radic Biol Med. 1994 Jun; 16(6):703-12. Vissers MC, Stern A, Kuypers F, van den Berg J, Winterbourn CC. PMID: 8070673.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    221. Modification of LCAT activity and HDL structure. New links between cigarette smoke and coronary heart disease risk. Arterioscler Thromb. 1994 Feb; 14(2):248-53. McCall MR, van den Berg JJ, Kuypers FA, Tribble DL, Krauss RM, Knoff LJ, Forte TM. PMID: 8305416.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    222. Loss of red blood cell viability associated with limited thermal inactivation of extracellular HIV-1. Vox Sang. 1994; 67(3):260-6. Stromberg RR, Kuypers FA, Sawyer L, Friedman LI, Cole M, Tran K, Hanson CV. PMID: 7863625.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    223. Loss of Red Blood Cell Viability Associated with Limited Thermal Inactivation of Extracellular HIV-1. Vox Sanguinis. 1994 Jan 1; 67(3):260-266. Stromberg SR, Kuypers KF, Sawyer SL, Friedman FL, Cole CM, Tran TK, Hanson HC. .
      View in: Publisher Site   Mentions:
    224. Compartmentalization of oxidative injury in low density lipoproteins (LDL): Evidence for two kinetic pools corresponding to the LDL surface monolayer and hydrophobic core. Free Radical Biology and Medicine. 1993 Nov 1; 15(5):540. Tribble TD, Lansberg LM, Krauss KR, Kuypers KF, van den Berg vJ. .
      View in: Publisher Site   Mentions:
    225. Oxidation of unsaturated membrane phospholipids and cholesterol by hypochlorous acid. Free Radical Biology and Medicine. 1993 Nov 1; 15(5):552. van den Berg vJ, Kuypers KF, Winterbourn WC. .
      View in: Publisher Site   Mentions:
    226. Hypochlorous acid-mediated modification of cholesterol and phospholipid: analysis of reaction products by gas chromatography-mass spectrometry. J Lipid Res. 1993 Nov; 34(11):2005-12. van den Berg JJ, Winterbourn CC, Kuypers FA. PMID: 8263423.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    227. Effects of dietary fats from animal and plant sources on diet-induced fatty streak lesions in C57BL/6J mice. J Lipid Res. 1993 Aug; 34(8):1413-22. Nishina PM, Lowe S, Verstuyft J, Naggert JK, Kuypers FA, Paigen B. PMID: 8409772.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    228. Atherosclerosis and plasma and liver lipids in nine inbred strains of mice. Lipids. 1993 Jul; 28(7):599-605. Nishina PM, Wang J, Toyofuku W, Kuypers FA, Ishida BY, Paigen B. PMID: 8355588.
      View in: PubMed   Mentions: 40     Fields:    Translation:Animals
    229. Transbilayer mobility and distribution of red cell phospholipids during storage. J Clin Invest. 1993 Jul; 92(1):308-14. Geldwerth D, Kuypers FA, Bütikofer P, Allary M, Lubin BH, Devaux PF. PMID: 8325999; PMCID: PMC293596.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    230. Conformational changes in oxidized phospholipids and their preferential hydrolysis by phospholipase A2: a monolayer study. Biochemistry. 1993 May 11; 32(18):4962-7. van den Berg JJ, Op den Kamp JA, Lubin BH, Kuypers FA. PMID: 8490032.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    231. Iron-dependent free radical generation from the antimalarial agent artemisinin (qinghaosu). Antimicrob Agents Chemother. 1993 May; 37(5):1108-14. Meshnick SR, Yang YZ, Lima V, Kuypers F, Kamchonwongpaisan S, Yuthavong Y. PMID: 8517699; PMCID: PMC187911.
      View in: PubMed   Mentions: 77     Fields:    Translation:Animals
    232. Generation of phosphatidic acid during calcium-loading of human erythrocytes. Evidence for a phosphatidylcholine-hydrolyzing phospholipase D. Eur J Biochem. 1993 Apr 01; 213(1):367-75. Bütikofer P, Yee MC, Schott MA, Lubin BH, Kuypers FA. PMID: 8386626.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    233. Role of oxygen and carbon radicals in hemoglobin oxidation. Arch Biochem Biophys. 1993 Apr; 302(1):233-44. Minetti M, Mallozzi C, Scorza G, Scott MD, Kuypers FA, Lubin BH. PMID: 8385900.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    234. The distribution of erythrocyte phospholipids in hereditary spherocytosis demonstrates a minimal role for erythrocyte spectrin on phospholipid diffusion and asymmetry. Blood. 1993 Feb 15; 81(4):1051-7. Kuypers FA, Lubin BH, Yee M, Agre P, Devaux PF, Geldwerth D. PMID: 8427987.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    235. The distribution of erythrocyte phospholipids in hereditary spherocytosis demonstrates a minimal role for erythrocyte spectrin on phospholipid diffusion and asymmetry. Blood. 1993 Feb 15; 81(4):1051-1057. Kuypers KF, Lubin LB, Yee YM, Agre AP, Devaux DP, Geldwerth GD. .
      View in: Publisher Site   Mentions:
    236. Chlorohydrin formation from unsaturated fatty acids reacted with hypochlorous acid. Arch Biochem Biophys. 1992 Aug 01; 296(2):547-55. Winterbourn CC, van den Berg JJ, Roitman E, Kuypers FA. PMID: 1321589.
      View in: PubMed   Mentions: 47     Fields:    
    237. Kinetics and site specificity of hydroperoxide-induced oxidative damage in red blood cells. Free Radic Biol Med. 1992; 12(6):487-98. van den Berg JJ, Op den Kamp JA, Lubin BH, Roelofsen B, Kuypers FA. PMID: 1601324.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    238. Oxidative Damage and Repair of Human Erythrocyte Lipids. Dynamics of Membrane Assembly. 1992 Jan 1; 141-151. van den Berg vJ, Kuypers KF. .
      View in: Publisher Site   Mentions:
    239. Characterization of the complement sensitivity of calcium loaded human erythrocytes. Blood. 1991 Dec 1; 78(11):3056-3065. Test TS, Butikofer BP, Yee YM, Kuypers KF, Lubin LB. .
      View in: Publisher Site   Mentions:
    240. Characterization of the complement sensitivity of calcium loaded human erythrocytes. Blood. 1991 Dec 01; 78(11):3056-65. Test ST, Bütikofer P, Yee MC, Kuypers FA, Lubin B. PMID: 1720041.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    241. Erythrocyte defense against hydrogen peroxide: preeminent importance of catalase. J Lab Clin Med. 1991 Jul; 118(1):7-16. Scott MD, Lubin BH, Zuo L, Kuypers FA. PMID: 2066646.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    242. Application of liquid chromatography-thermospray mass spectrometry in the analysis of glycerophospholipid molecular species. J Chromatogr. 1991 Jan 02; 562(1-2):191-206. Kuypers FA, Bütikofer P, Shackleton CH. PMID: 2026692.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    243. Direct and continuous measurement of hydroperoxide-induced oxidative stress on the membrane of intact erythrocytes. Free Radic Biol Med. 1991; 11(3):255-61. van den Berg JJ, Kuypers FA, Lubin BH, Roelofsen B, Op den Kamp JA. PMID: 1937143.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    244. Recognition signals for phagocytic removal of favic, malaria-infected and sickled erythrocytes. Adv Exp Med Biol. 1991; 307:317-27. Arese P, Turrini F, Bussolino F, Lutz HU, Chiu D, Zuo L, Kuypers F, Ginsburg H. PMID: 1805595.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    245. Increased n-3 polyunsaturated fatty acid content of red blood cells from fish oil-fed rabbits increases in vitro lipid peroxidation, but decreases hemolysis. Free Radic Biol Med. 1991; 11(4):393-9. van den Berg JJ, de Fouw NJ, Kuypers FA, Roelofsen B, Houtsmuller UM, Op den Kamp JA. PMID: 1797625.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    246. PHOSPHOLIPID REPAIR IN HUMAN ERYTHROCYTES. Oxidative Damage & Repair. 1991 Jan 1; 557-563. Lubin LB, Kuypers KF. .
      View in: Publisher Site   Mentions:
    247. Molecular species analysis of the glycosylphosphatidylinositol anchor of Torpedo marmorata acetylcholinesterase. J Biol Chem. 1990 Nov 05; 265(31):18983-7. Bütikofer P, Kuypers FA, Shackleton C, Brodbeck U, Stieger S. PMID: 2146267.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    248. Use of ektacytometry to determine red cell susceptibility to oxidative stress. J Lab Clin Med. 1990 Oct; 116(4):535-45. Kuypers FA, Scott MD, Schott MA, Lubin B, Chiu DT. PMID: 2212862.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    249. Transbilayer distribution and mobility of phosphatidylinositol in human red blood cells. J Biol Chem. 1990 Sep 25; 265(27):16035-8. Bütikofer P, Lin ZW, Chiu DT, Lubin B, Kuypers FA. PMID: 2168875.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    250. Parasite uptake of desferroxamine: a prerequisite for antimalarial activity. Br J Haematol. 1990 Aug; 75(4):598-602. Scott MD, Ranz A, Kuypers FA, Lubin BH, Meshnick SR. PMID: 1698449.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    251. Excess of red cell membrane proteins in hereditary high-phosphatidylcholine hemolytic anemia. Am J Hematol. 1990 Jul; 34(3):186-92. Lane PA, Kuypers FA, Clark MR, Andrews DA, Wagner GM, Butikofer P, Shapiro AD, Chiu DT, Lubin BH, Mentzer WC. PMID: 2363413.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    252. Effect of osmotic lysis and resealing on red cell structure and function. J Lab Clin Med. 1990 Apr; 115(4):470-80. Scott MD, Kuypers FA, Butikofer P, Bookchin RM, Ortiz OE, Lubin BH. PMID: 1691257.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    253. The cooperative action of vitamins E and C in the protection against peroxidation of parinaric acid in human erythrocyte membranes. Chem Phys Lipids. 1990 Mar; 53(4):309-20. van den Berg JJ, Kuypers FA, Roelofsen B, Op den Kamp JA. PMID: 2340603.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    254. Lability of red blood cell membranes to lipid peroxidation: application to humans fed polyunsaturated lipids. Lipids. 1990 Feb; 25(2):111-4. Fraga CG, Tappel AL, Leibovitz BE, Kuypers F, Chiu D, Iacono JM, Kelley DS. PMID: 2329922.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    255. The Role of Oxidation in Diseases of the Human Erythrocyte. Topics in Pediatrics. 1990 Jan 1; 34-47. Lubin LB, Kuypers KF, Vichinsky VE, Chiu CD. .
      View in: Publisher Site   Mentions:
    256. Preferential Release of Glycosyl-Phosphatidylinositol Anchored Proteins from Human Red Blood Cells during Vesiculation. Dynamics and Biogenesis of Membranes. 1990 Jan 1; 29-41. Bütikofer BP, Test TS, Chiu CD, Lubin LB, Kuypers KF. .
      View in: Publisher Site   Mentions:
    257. Role of carbon-centered radicals in the conversion of hemoglobin to hemicromes. Free Radical Biology and Medicine. 1990 Jan 1; 9:87. Minetti MM, Mallozzi MC, Scorza SG, Scott SM, Kuypers KF, Lubin LB. .
      View in: Publisher Site   Mentions:
    258. The hydroperoxide-induced oxidation kinetics of hemoglobin and parinaric acid in red blood cells. Free Radical Biology and Medicine. 1990 Jan 1; 9:184. van den Berg vJ, Kamp KJ, Roelofsen RB, Lubin LB, Kuypers KF. .
      View in: Publisher Site   Mentions:
    259. Enhancement of erythrocyte superoxide dismutase activity: effects on cellular oxidant defense. Blood. 1989 Nov 15; 74(7):2542-2549. Scott SM, Eaton EJ, Kuypers KF, Chiu CD, Lubin LB. .
      View in: Publisher Site   Mentions:
    260. Enhancement of erythrocyte superoxide dismutase activity: effects on cellular oxidant defense. Blood. 1989 Nov 15; 74(7):2542-9. Scott MD, Eaton JW, Kuypers FA, Chiu DT, Lubin BH. PMID: 2553167.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    261. Qinghaosu-mediated oxidation in normal and abnormal erythrocytes. J Lab Clin Med. 1989 Oct; 114(4):401-6. Scott MD, Meshnick SR, Williams RA, Chiu DT, Pan HC, Lubin BH, Kuypers FA. PMID: 2794752.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    262. Lipid peroxidation in human red cells. Semin Hematol. 1989 Oct; 26(4):257-76. Chiu D, Kuypers F, Lubin B. PMID: 2683096.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    263. Enrichment of two glycosyl-phosphatidylinositol-anchored proteins, acetylcholinesterase and decay accelerating factor, in vesicles released from human red blood cells. Blood. 1989 Oct; 74(5):1481-5. Bütikofer P, Kuypers FA, Xu CM, Chiu DT, Lubin B. PMID: 2477079.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    264. Enrichment of two glycosyl-phosphatidylinositol-anchored proteins, acetylcholinesterase and decay accelerating factor, in vesicles released from human red blood cells. Blood. 1989 Oct 1; 74(5):1481-1485. Butikofer BP, Kuypers KF, Xu XC, Chiu CD, Lubin LB. .
      View in: Publisher Site   Mentions:
    265. Chlorpromazine inhibits vesiculation, alters phosphoinositide turnover and changes deformability of ATP-depleted RBCs. Blood. 1989 May 1; 73(6):1699-1704. Butikofer BP, Lin LZ, Kuypers KF, Scott SM, Xu XC, Wagner WG, Chiu CD, Lubin LB. .
      View in: Publisher Site   Mentions:
    266. Chlorpromazine inhibits vesiculation, alters phosphoinositide turnover and changes deformability of ATP-depleted RBCs. Blood. 1989 May 01; 73(6):1699-704. Bütikofer P, Lin ZW, Kuypers FA, Scott MD, Xu CM, Wagner GM, Chiu DT, Lubin B. PMID: 2540856.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    267. Influence of phosphatidylcholine molecular species composition on stability of the erythrocyte membrane. Biochem Soc Trans. 1989 Apr; 17(2):284-6. Roelofsen B, Kuypers FA, Op den Kamp JA, van Deenen LL. PMID: 2753205.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    268. Red cell deformability and lipid composition in two forms of acanthocytosis: enrichment of acanthocytic populations by density gradient centrifugation. J Lab Clin Med. 1989 Apr; 113(4):469-81. Clark MR, Aminoff MJ, Chiu DT, Kuypers FA, Friend DS. PMID: 2703759.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    269. Erythrocyte phospholipid organization and vesiculation in hereditary high red cell membrane phosphatidylcholine hemolytic anemia. J Lab Clin Med. 1989 Mar; 113(3):278-84. Butikofer P, Kuypers FA, Lane P, Chiu DT, Lubin BH, Ott P. PMID: 2926237.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    270. Red cell membrane lipid dynamics. Prog Clin Biol Res. 1989; 319:507-22; discussion 523-4. Lubin B, Kuypers F, Chiu D. PMID: 2695937.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    271. Activated oxygen mediates the antimalarial activity of qinghaosu. Prog Clin Biol Res. 1989; 313:95-104. Meshnick SR, Tsang TW, Lin FB, Pan HZ, Chang CN, Kuypers F, Chiu D, Lubin B. PMID: 2675120.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    272. Lipid alterations and cellular properties of sickle red cells. Ann N Y Acad Sci. 1989; 565:86-95. Lubin B, Kuypers F, Chiu D. PMID: 2672973.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    273. The use of cis-parinaric acid to determine lipid peroxidation in human erythrocyte membranes. Comparison of normal and sickle erythrocyte membranes. Biochim Biophys Acta. 1988 Sep 15; 944(1):29-39. Van den Berg JJ, Kuypers FA, Qju JH, Chiu D, Lubin B, Roelofsen B, Op den Kamp JA. PMID: 3415998.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    274. Diet-induced asymmetry of the phosphatidylcholine fatty acyl composition in rat erythrocyte membranes. J Lab Clin Med. 1988 May; 111(5):529-36. Kuypers FA, Abraham S, Lubin B, Chiu D. PMID: 3202919.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    275. The molecular species composition of phosphatidylcholine affects cellular properties in normal and sickle erythrocytes. Blood. 1987 Oct; 70(4):1111-8. Kuypers FA, Chiu D, Mohandas N, Roelofsen B, Op den Kamp JA, Lubin B. PMID: 3651600.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    276. The molecular species composition of phosphatidylcholine affects cellular properties in normal and sickle erythrocytes. Blood. 1987 Oct 1; 70(4):1111-1118. Kuypers KF, Chiu CD, Mohandas MN, Roelofsen RB, Op den Kamp OJ, Lubin LB. .
      View in: Publisher Site   Mentions:
    277. Parinaric acid as a sensitive fluorescent probe for the determination of lipid peroxidation. Biochim Biophys Acta. 1987 Sep 25; 921(2):266-74. Kuypers FA, van den Berg JJ, Schalkwijk C, Roelofsen B, Op den Kamp JA. PMID: 3651488.
      View in: PubMed   Mentions: 12     Fields:    
    278. Effects of altered phospholipid molecular species on erythrocyte membranes. Ann N Y Acad Sci. 1987; 492:145-55. van Deenen LL, Kuypers FA, Op den Kamp JA, Roelofsen B. PMID: 3474924.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    279. The rate of uptake and efflux of phosphatidylcholine from human erythrocytes depends on the fatty acyl composition of the exchanging species. Biochim Biophys Acta. 1986 May 09; 857(1):75-84. Kuypers FA, Andriesse X, Child P, Roelofsen B, Op den Kamp JA, van Deenen LL. PMID: 3964706.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    280. Effect of membrane cholesterol on dimyristoylphosphatidylcholine-induced vesiculation of human red blood cells. Biochim Biophys Acta. 1986 Feb 27; 855(2):293-301. Frenkel EJ, Kuypers FA, Op den Kamp JA, Roelofsen B, Ott P. PMID: 3947626.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    281. Survival of rabbit and horse erythrocytes in vivo after changing the fatty acyl composition of their phosphatidylcholine. Biochim Biophys Acta. 1985 Oct 10; 819(2):170-8. Kuypers FA, Easton EW, van den Hoven R, Wensing T, Roelofsen B, op den Kamp JA, van Deenen LL. PMID: 4041456.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    282. Lipid molecular shape affects erythrocyte morphology: a study involving replacement of native phosphatidylcholine with different species followed by treatment of cells with sphingomyelinase C or phospholipase A2. J Cell Biol. 1985 Oct; 101(4):1455-62. Christiansson A, Kuypers FA, Roelofsen B, Op den Kamp JA, van Deenen LL. PMID: 4044642; PMCID: PMC2113896.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    283. The phospholipid organisation in the membranes of McLeod and Leach phenotype erythrocytes. FEBS Lett. 1985 May 06; 184(1):20-4. Kuypers FA, van Linde-Sibenius Trip M, Roelofsen B, Op den Kamp JA, Tanner MJ, Anstee DJ. PMID: 3987904.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    284. Acyl selectivity in the transfer of molecular species of phosphatidylcholines from human erythrocytes. Biochim Biophys Acta. 1985 Jan 25; 812(2):321-32. Child P, Myher JJ, Kuypers FA, Op den Kamp JA, Kuksis A, Van Deenen LL. PMID: 3838142.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    285. Shape changes in human erythrocytes induced by replacement of the native phosphatidylcholine with species containing various fatty acids. J Cell Biol. 1984 Dec; 99(6):2260-7. Kuypers FA, Roelofsen B, Berendsen W, Op den Kamp JA, van Deenen LL. PMID: 6501425; PMCID: PMC2113552.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    286. A comparative fluorescence polarization study of cis-parinaroyl-phosphatidylcholine and diphenylhexatriene in membranes containing different amounts of cholesterol. Chem Phys Lipids. 1984 Aug; 35(3):247-58. Christiansson A, Kuypers FA, Roelofsen B, Wirtz KW, Op den Kamp JA. PMID: 6548417.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    287. Rhnull human erythrocytes have an abnormal membrane phospholipid organization. Biochem J. 1984 Aug 01; 221(3):931-4. Kuypers F, van Linde-Sibenius-Trip M, Roelofsen B, Tanner MJ, Anstee DJ, Op den Kamp JA. PMID: 6433893; PMCID: PMC1144129.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    288. The membrane of intact human erythrocytes tolerates only limited changes in the fatty acid composition of its phosphatidylcholine. Biochim Biophys Acta. 1984 Jan 25; 769(2):337-47. Kuypers FA, Roelofsen B, Op den Kamp JA, Van Deenen LL. PMID: 6696887.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    Franciscus's Networks
    Concepts (791)
    Derived automatically from this person's publications.
    _
    Co-Authors (31)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _