John Pluvinage, MD, PhD

Title(s)Resident, Neurology
SchoolSchool of Medicine
Address35 Medical Center Way, #001
San Francisco CA 94143
PronounsAll pronouns
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    Collapse Biography 
    Collapse Education and Training
    Stanford UniversityMD06/2021
    Stanford UniversityPhD06/2021

    Collapse Research 
    Collapse Research Activities and Funding
    Preclinical evaluation of a therapeutic CD22 antibody in feline Niemann-Pick Type C1 disease
    Ara Parseghian Medical Research Fund Jul 1, 2022 - Jul 1, 2023
    Role: Co-Investigator
    Mechanisms of Age-Related Microglial Impairment and Rejuvenation in Alzheimer's Disease
    NIH F30AG060638Aug 2, 2018 - Aug 1, 2021
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Permissive central tolerance plus defective peripheral checkpoints licence pathogenic memory B cells in CASPR2-antibody encephalitis. bioRxiv. 2025 Jan 14. Sun B, Fernandes D, Kienzler AK, Paneva S, Harrison R, Ramanathan S, Harrison AL, Makuch M, Fichtner ML, Donat RF, Akdeniz D, Bayuangga H, Im MG, Williams R, Vasconcelos A, Thomsen S, Fower A, Sun R, Fox H, Mgbachi V, Davies A, Tseng M, Handel A, Kelly M, Zhao M, Bancroft J, Bashford-Rogers R, Pluvinage JV, Dandekar R, Alvarenga BD, Dustin L, Rinaldi S, Owens R, Anthony D, Bennett DL, Waters P, Davis SJ, Wilson MR, O'Connor KC, Soltys J, Carvalho AL, Irani SR. PMID: 39868113; PMCID: PMC11760777.
      View in: PubMed   Mentions:
    2. Molecular mimicry in multisystem inflammatory syndrome in children. Nature. 2024 Aug; 632(8025):622-629. Bodansky A, Mettelman RC, Sabatino JJ, Vazquez SE, Chou J, Novak T, Moffitt KL, Miller HS, Kung AF, Rackaityte E, Zamecnik CR, Rajan JV, Kortbawi H, Mandel-Brehm C, Mitchell A, Wang CY, Saxena A, Zorn K, Yu DJL, Pogorelyy MV, Awad W, Kirk AM, Asaki J, Pluvinage JV, Wilson MR, Zambrano LD, Campbell AP, Overcoming COVID-19 Network Investigators, Thomas PG, Randolph AG, Anderson MS, DeRisi JL. PMID: 39112696; PMCID: PMC11324515.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    3. Transcobalamin receptor antibodies in autoimmune vitamin B12 central deficiency. Sci Transl Med. 2024 Jun 26; 16(753):eadl3758. Pluvinage JV, Ngo T, Fouassier C, McDonagh M, Holmes BB, Bartley CM, Kondapavulur S, Hurabielle C, Bodansky A, Pai V, Hinman S, Aslanpour A, Alvarenga BD, Zorn KC, Zamecnik C, McCann A, Asencor AI, Huynh T, Browne W, Tubati A, Haney MS, Douglas VC, Louine M, Cree BAC, Hauser SL, Seeley W, Baranzini SE, Wells JA, Spudich S, Farhadian S, Ramachandran PS, Gillum L, Hales CM, Zikherman J, Anderson MS, Yazdany J, Smith B, Nath A, Suh G, Flanagan EP, Green AJ, Green R, Gelfand JM, DeRisi JL, Pleasure SJ, Wilson MR. PMID: 38924428; PMCID: PMC11520464.
      View in: PubMed   Mentions: 1     Fields:    
    4. MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint. Proc Natl Acad Sci U S A. 2023 03 14; 120(11):e2215376120. Smith BAH, Deutzmann A, Correa KM, Delaveris CS, Dhanasekaran R, Dove CG, Sullivan DK, Wisnovsky S, Stark JC, Pluvinage JV, Swaminathan S, Riley NM, Rajan A, Majeti R, Felsher DW, Bertozzi CR. PMID: 36897988; PMCID: PMC10089186.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    5. The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C. Sci Transl Med. 2021 12; 13(622):eabg2919. Pluvinage JV, Sun J, Claes C, Flynn RA, Haney MS, Iram T, Meng X, Lindemann R, Riley NM, Danhash E, Chadarevian JP, Tapp E, Gate D, Kondapavulur S, Cobos I, Chetty S, Pa?ca AM, Pa?ca SP, Berry-Kravis E, Bertozzi CR, Blurton-Jones M, Wyss-Coray T. PMID: 34851695; PMCID: PMC9067636.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    6. Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain. Nat Neurosci. 2020 02; 23(2):194-208. Marschallinger J, Iram T, Zardeneta M, Lee SE, Lehallier B, Haney MS, Pluvinage JV, Mathur V, Hahn O, Morgens DW, Kim J, Tevini J, Felder TK, Wolinski H, Bertozzi CR, Bassik MC, Aigner L, Wyss-Coray T. PMID: 31959936; PMCID: PMC7595134.
      View in: PubMed   Mentions: 436     Fields:    Translation:HumansAnimalsCells
    7. Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease. Nature. 2020 01; 577(7790):399-404. Gate D, Saligrama N, Leventhal O, Yang AC, Unger MS, Middeldorp J, Chen K, Lehallier B, Channappa D, De Los Santos MB, McBride A, Pluvinage J, Elahi F, Tam GK, Kim Y, Greicius M, Wagner AD, Aigner L, Galasko DR, Davis MM, Wyss-Coray T. PMID: 31915375; PMCID: PMC7445078.
      View in: PubMed   Mentions: 380     Fields:    Translation:HumansCells
    8. Systemic factors as mediators of brain homeostasis, ageing and neurodegeneration. Nat Rev Neurosci. 2020 02; 21(2):93-102. Pluvinage JV, Wyss-Coray T. PMID: 31913356.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    9. Single-cell analysis reveals T cell infiltration in old neurogenic niches. Nature. 2019 07; 571(7764):205-210. Dulken BW, Buckley MT, Navarro Negredo P, Saligrama N, Cayrol R, Leeman DS, George BM, Boutet SC, Hebestreit K, Pluvinage JV, Wyss-Coray T, Weissman IL, Vogel H, Davis MM, Brunet A. PMID: 31270459; PMCID: PMC7111535.
      View in: PubMed   Mentions: 227     Fields:    Translation:AnimalsCells
    10. RUNX3 levels in human hematopoietic progenitors are regulated by aging and dictate erythroid-myeloid balance. Haematologica. 2020 04; 105(4):905-913. Balogh P, Adelman ER, Pluvinage JV, Capaldo BJ, Freeman KC, Singh S, Elagib KE, Nakamura Y, Kurita R, Sashida G, Zunder ER, Li H, Gru AA, Price EA, Schrier SL, Weissman IL, Figueroa ME, Pang WW, Goldfarb AN. PMID: 31171641; PMCID: PMC7109730.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    11. CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. Nature. 2019 04; 568(7751):187-192. Pluvinage JV, Haney MS, Smith BAH, Sun J, Iram T, Bonanno L, Li L, Lee DP, Morgens DW, Yang AC, Shuken SR, Gate D, Scott M, Khatri P, Luo J, Bertozzi CR, Bassik MC, Wyss-Coray T. PMID: 30944478; PMCID: PMC6574119.
      View in: PubMed   Mentions: 170     Fields:    Translation:AnimalsCells
    12. Microglial Barriers to Viral Gene Delivery. Neuron. 2017 Feb 08; 93(3):468-470. Pluvinage JV, Wyss-Coray T. PMID: 28182900.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    13. Prospective isolation of human erythroid lineage-committed progenitors. Proc Natl Acad Sci U S A. 2015 Aug 04; 112(31):9638-43. Mori Y, Chen JY, Pluvinage JV, Seita J, Weissman IL. PMID: 26195758; PMCID: PMC4534255.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    14. Osteoclast derivation from mouse bone marrow. J Vis Exp. 2014 Nov 06; (93):e52056. Tevlin R, McArdle A, Chan CK, Pluvinage J, Walmsley GG, Wearda T, Marecic O, Hu MS, Paik KJ, Senarath-Yapa K, Atashroo DA, Zielins ER, Wan DC, Weissman IL, Longaker MT. PMID: 25407120; PMCID: PMC4353410.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    15. Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes. Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8):3011-6. Pang WW, Pluvinage JV, Price EA, Sridhar K, Arber DA, Greenberg PL, Schrier SL, Park CY, Weissman IL. PMID: 23388639; PMCID: PMC3581956.
      View in: PubMed   Mentions: 141     Fields:    Translation:HumansAnimalsCells
    16. Reduced ribosomal protein gene dosage and p53 activation in low-risk myelodysplastic syndrome. Blood. 2011 Sep 29; 118(13):3622-33. McGowan KA, Pang WW, Bhardwaj R, Perez MG, Pluvinage JV, Glader BE, Malek R, Mendrysa SM, Weissman IL, Park CY, Barsh GS. PMID: 21788341; PMCID: PMC3186336.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
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