Mark Anderson, MD, PhD

Title(s)Professor, Diabetes Center
SchoolSchool of Medicine
Address513 Parnassus Ave, HSW, #1114
San Francisco CA 94143
Phone415-502-8052
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    Collapse Biography 
    Collapse Education and Training
    University of ChicagoM.D.1994Pritzker School of Medicine
    University of ChicagoPhD1992Immunology
    Collapse Awards and Honors
    2004Pew Scholar
    2009Robert B. Friend and Michelle M. Friend Endowed Chair in Diabetes Research
    2009American Society of Clinical Investigation
    UCSF2012Byers Award in Basic Science
    2016American Association of Physicians
    University of Chicago2019Distinguished Alumni Award
    2020National Academy of Medicine

    Collapse Overview 
    Collapse Overview
    EDUCATION/CLINICAL TRAINING
    MD: MD, PhD, University of Chicago, 1994
    Residency: University of Minnesota, MD, Internal Medicine, 1994-1997
    Chief Resident, University of Minnesota 1997-1998
    Fellowship: Massachusetts General Hospital, Adult Endocrinology, 1998-2001
    Board Certification: Endocrinology and Metabolism, 2001, Renewed 2012

    ACADEMIC INTERESTS
    The main research interest of our laboratory group is to examine the genetic control of autoimmune diseases to gain a better understanding of the mechanisms by which immune tolerance is broken. A major focus of our lab group is a human autoimmune syndrome called Autoimmune Polyglandular Syndrome Type 1 (APS1 or APECED), which is classically manifested by an autoimmune attack directed at multiple endocrine organs. This disease is inherited in a monogenic autosomal recessive fashion and the defective gene has been identified and is called Aire (for autoimmune regulator). Aire knockout mice, like their human counterparts, develop an autoimmune disease that is targeted to multiple organs. Through the use of the mouse model we, along with others, have determined that Aire plays an important role in immune tolerance by promoting the expression of many self proteins in specialized antigen presenting cells in the thymus called medullary epithelial cells (mTEC’s).

    Recently, we have determined that this process is not only critical in the thymus, but also in peripheral lymphoid organs. Current studies in the lab are directed at further understanding the relative contribution of specialized Aire-expressing cells to immune tolerance in multiple autoimmune disease models. In addition to these ongoing studies, our laboratory is also interested the pathogenesis of autoimmune diabetes and in developing other models of autoimmune disease by using transgenic, knockout, and knock-in approaches.



    CLINICAL INTERESTS:
    Type 1 diabetes and associated autoimmune disorders

    Appointments: 415-353-2350

    Collapse Research 
    Collapse Research Activities and Funding
    Alterations of leukocyte integrin signaling leading to diabetes and autoimmunity
    NIH R01AI170841Aug 1, 2022 - Jul 31, 2026
    Role: Co-Principal Investigator
    Tuning peptide specifities for T cell tolerance in Type 1 diabetes
    NIH R01DK133443Jun 1, 2022 - Apr 30, 2026
    Role: Principal Investigator
    STAT3 variants as a rheostat of immune tolerance
    NIH P01AI155393Feb 17, 2022 - Jan 31, 2027
    Role: Principal Investigator
    Medical Scientist Training Program (T32 NRSA Training Grant)
    NIH T32GM141323Jul 1, 2021 - Jun 30, 2026
    Role: Principal Investigator
    Modeling autoimmune pathogenesis and beta cell destruction by T1D immune systems
    NIH U01DK123559Sep 20, 2019 - May 31, 2023
    Role: Co-Principal Investigator
    Using human stem cell-derived thymic epithelium to remodel T1D immune tolerance
    NIH U01DK107383Jul 1, 2016 - Dec 31, 2020
    Role: Principal Investigator
    Using human stem cell-derived thymic epithelium to remodel T1D immune tolerance
    NIH/NIDDK R01DK107383Jul 1, 2016 - Jun 30, 2020
    Role: Principal Investigator
    Disruption of T cell tolerance in type 1 diabetes
    NIH P01AI118688Jun 8, 2016 - May 31, 2021
    Role: Principal Investigator
    Developing eTACs as a Novel Method of Tolerance in Type 1 Diabetes
    NIH R01DK101622Apr 2, 2014 - Mar 31, 2019
    Role: Principal Investigator
    Thymic medullary epithelial cell turnover and control of immune tolerance
    NIH R01AI097457Dec 1, 2011 - Jul 20, 2017
    Role: Principal Investigator
    Aire-defieciency as a novel model of uveitis
    NIH R01EY016408Jun 1, 2005 - Jun 30, 2015
    Role: Principal Investigator
    Role of the AIRE Gene in the Development of Autoimmunity
    NIH K08DK059958Sep 1, 2002 - Aug 31, 2008
    Role: Principal Investigator
    Medical Scientist Training Program
    NIH T32GM007618Jul 1, 1978 - Jun 30, 2021
    Role: Principal Investigator
    Immune Tolerance and Autoimmunity
    NIH P01AI035297Jul 31, 2012
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Collaboration Interests

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency. Nature. 2023 Nov 08. Le Voyer T, Parent AV, Liu X, Cederholm A, Gervais A, Rosain J, Nguyen T, Perez Lorenzo M, Rackaityte E, Rinchai D, Zhang P, Bizien L, Hancioglu G, Ghillani-Dalbin P, Charuel JL, Philippot Q, Gueye MS, Maglorius Renkilaraj MRL, Ogishi M, Soudée C, Migaud M, Rozenberg F, Momenilandi M, Riller Q, Imberti L, Delmonte OM, Müller G, Keller B, Orrego J, Franco Gallego WA, Rubin T, Emiroglu M, Parvaneh N, Eriksson D, Aranda-Guillen M, Berrios DI, Vong L, Katelaris CH, Mustillo P, Raedler J, Bohlen J, Bengi Celik J, Astudillo C, Winter S, NF-?B Consortium, COVID Human Genetic Effort, McLean C, Guffroy A, DeRisi JL, Yu D, Miller C, Feng Y, Guichard A, Béziat V, Bustamante J, Pan-Hammarström Q, Zhang Y, Rosen LB, Holland SM, Bosticardo M, Kenney H, Castagnoli R, Slade CA, Boztug K, Mahlaoui N, Latour S, Abraham RS, Lougaris V, Hauck F, Sediva A, Atschekzei F, Sogkas G, Poli MC, Slatter MA, Palterer B, Keller MD, Pinzon-Charry A, Sullivan A, Droney L, Suan D, Wong M, Kane A, Hu H, Ma C, Grombiríková H, Ciznar P, Dalal I, Aladjidi N, Hie M, Lazaro E, Franco J, Keles S, Malphettes M, Pasquet M, Maccari ME, Meinhardt A, Ikinciogullari A, Shahrooei M, Celmeli F, Frosk P, Goodnow CC, Gray PE, Belot A, Kuehn HS, Rosenzweig SD, Miyara M, Licciardi F, Servettaz A, Barlogis V, Le Guenno G, Herrmann VM, Kuijpers T, Ducoux G, Sarrot-Reynauld F, Schuetz C, Cunningham-Rundles C, Rieux-Laucat F, Tangye SG, Sobacchi C, Doffinger R, Warnatz K, Grimbacher B, Fieschi C, Berteloot L, Bryant VL, Trouillet Assant S, Su H, Neven B, Abel L, Zhang Q, Boisson B, Cobat A, Jouanguy E, Kampe O, Bastard P, Roifman CM, Landegren N, Notarangelo LD, Anderson MS, Casanova JL, Puel A. PMID: 37938781.
      View in: PubMed   Mentions:    Fields:    
    2. Validation of a murine proteome-wide phage display library for identification of autoantibody specificities. JCI Insight. 2023 Nov 07. Rackaityte E, Proekt I, Miller HS, Ramesh A, Brooks JF, Kung AF, Mandel-Brehm C, Yu DJ, Zamecnik CR, Bair R, Vazquez SE, Sunshine S, Abram CL, Lowell CA, Rizzuto G, Wilson MR, Zikherman J, Anderson MS, DeRisi JL. PMID: 37934865.
      View in: PubMed   Mentions:    Fields:    
    3. Ikaros is a principal regulator of Aire+ mTEC homeostasis, thymic mimetic cell diversity, and central tolerance. Sci Immunol. 2023 Oct 27; 8(88):eabq3109. Sin JH, Sucharov J, Kashyap S, Wang Y, Proekt I, Liu X, Parent AV, Gupta A, Kastner P, Chan S, Gardner JM, Ntranos V, Miller CN, Anderson MS, Schjerven H, Waterfield MR. PMID: 37889983.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    4. Immunosuppression causes dynamic changes in expression QTLs in psoriatic skin. Nat Commun. 2023 Oct 07; 14(1):6268. Xiao Q, Mears J, Nathan A, Ishigaki K, Baglaenko Y, Lim N, Cooney LA, Harris KM, Anderson MS, Fox DA, Smilek DE, Krueger JG, Raychaudhuri S. PMID: 37805522; PMCID: PMC10560299.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. T cell deletional tolerance restricts AQP4 but not MOG CNS autoimmunity. Proc Natl Acad Sci U S A. 2023 07 25; 120(30):e2306572120. Sagan SA, Moinfar Z, Moseley CE, Dandekar R, Spencer CM, Verkman AS, Ottersen OP, Sobel RA, Sidney J, Sette A, Anderson MS, Steinman L, Wilson MR, Sabatino JJ, Zamvil SS. PMID: 37463205; PMCID: PMC10372680.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    6. Autoantigen profiling reveals a shared post-COVID signature in fully recovered and long COVID patients. JCI Insight. 2023 06 08; 8(11). Bodansky A, Wang CY, Saxena A, Mitchell A, Kung AF, Takahashi S, Anglin K, Huang B, Hoh R, Lu S, Goldberg SA, Romero J, Tran B, Kirtikar R, Grebe H, So M, Greenhouse B, Durstenfeld MS, Hsue PY, Hellmuth J, Kelly JD, Martin JN, Anderson MS, Deeks SG, Henrich TJ, DeRisi JL, Peluso MJ. PMID: 37288661; PMCID: PMC10393220.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    7. A genomic data archive from the Network for Pancreatic Organ donors with Diabetes. Sci Data. 2023 05 26; 10(1):323. Perry DJ, Shapiro MR, Chamberlain SW, Kusmartseva I, Chamala S, Balzano-Nogueira L, Yang M, Brant JO, Brusko M, Williams MD, McGrail KM, McNichols J, Peters LD, Posgai AL, Kaddis JS, Mathews CE, Wasserfall CH, Webb-Robertson BM, Campbell-Thompson M, Schatz D, Evans-Molina C, Pugliese A, Concannon P, Anderson MS, German MS, Chamberlain CE, Atkinson MA, Brusko TM. PMID: 37237059; PMCID: PMC10219990.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial. Diabetes Care. 2023 05 01; 46(5):1005-1013. Russell WE, Bundy BN, Anderson MS, Cooney LA, Gitelman SE, Goland RS, Gottlieb PA, Greenbaum CJ, Haller MJ, Krischer JP, Libman IM, Linsley PS, Long SA, Lord SM, Moore DJ, Moore WV, Moran AM, Muir AB, Raskin P, Skyler JS, Wentworth JM, Wherrett DK, Wilson DM, Ziegler AG, Herold KC, Type 1 Diabetes TrialNet Study Group. PMID: 36920087; PMCID: PMC10154649.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsCTClinical Trials
    9. ABCC8-Related Monogenic Diabetes Presenting Like Type 1 Diabetes in an Adolescent. AACE Clin Case Rep. 2023 Jul-Aug; 9(4):101-103. Grier AE, McGill JB, Lord SM, Speake C, Greenbaum C, Chamberlain CE, German MS, Anderson MS, Hirsch IB. PMID: 37520758; PMCID: PMC10382606.
      View in: PubMed   Mentions:
    10. Validation of a murine proteome-wide phage display library for the identification of autoantibody specificities. bioRxiv. 2023 Apr 07. Rackaityte E, Proekt I, Miller HS, Ramesh A, Brooks JF, Kung AF, Mandel-Brehm C, Yu D, Zamecnik C, Bair R, Vazquez SE, Sunshine S, Abram CL, Lowell CA, Rizzuto G, Wilson MR, Zikherman J, Anderson MS, DeRisi JL. PMID: 37066405; PMCID: PMC10104109.
      View in: PubMed   Mentions:
    11. Case report: Discovery of a de novo FAM111B pathogenic variant in a patient with an APECED-like clinical phenotype. Front Immunol. 2023; 14:1133387. Ferré EMN, Yu Y, Oikonomou V, Hilfanova A, Lee CR, Rosen LB, Burbelo PD, Vazquez SE, Anderson MS, Barocha A, Heller T, Soldatos A, Holland SM, Walkiewicz MA, Lionakis MS. PMID: 36875114; PMCID: PMC9981804.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Autoantigen profiling reveals a shared post-COVID signature in fully recovered and Long COVID patients. medRxiv. 2023 Feb 09. Bodansky A, Wang CY, Saxena A, Mitchell A, Takahashi S, Anglin K, Huang B, Hoh R, Lu S, Goldberg SA, Romero J, Tran B, Kirtikar R, Grebe H, So M, Greenhouse B, Durstenfeld MS, Hsue PY, Hellmuth J, Kelly JD, Martin JN, Anderson MS, Deeks SG, Henrich TJ, DeRisi JL, Peluso MJ. PMID: 36798288; PMCID: PMC9934805.
      View in: PubMed   Mentions:
    13. Unlocking life-threatening COVID-19 through two types of inborn errors of type I IFNs. J Clin Invest. 2023 02 01; 133(3). Casanova JL, Anderson MS. PMID: 36719370; PMCID: PMC9888384.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    14. Autoantibodies to Perilipin-1 Define a Subset of Acquired Generalized Lipodystrophy. Diabetes. 2023 01 01; 72(1):59-70. Mandel-Brehm C, Vazquez SE, Liverman C, Cheng M, Quandt Z, Kung AF, Parent A, Miao B, Disse E, Cugnet-Anceau C, Dalle S, Orlova E, Frolova E, Alba D, Michels A, Oftedal BE, Lionakis MS, Husebye ES, Agarwal AK, Li X, Zhu C, Li Q, Oral E, Brown R, Anderson MS, Garg A, DeRisi JL. PMID: 35709010; PMCID: PMC9797316.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    15. Prevalence of type-1 interferon autoantibodies in adults with non-COVID-19 acute respiratory failure. Respir Res. 2022 Dec 16; 23(1):354. Ghale R, Spottiswoode N, Anderson MS, Mitchell A, Wang G, Calfee CS, DeRisi JL, Langelier CR. PMID: 36527083; PMCID: PMC9756918.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Autoantibody discovery across monogenic, acquired, and COVID-19-associated autoimmunity with scalable PhIP-seq. Elife. 2022 10 27; 11. Vazquez SE, Mann SA, Bodansky A, Kung AF, Quandt Z, Ferré EMN, Landegren N, Eriksson D, Bastard P, Zhang SY, Liu J, Mitchell A, Proekt I, Yu D, Mandel-Brehm C, Wang CY, Miao B, Sowa G, Zorn K, Chan AY, Tagi VM, Shimizu C, Tremoulet A, Lynch K, Wilson MR, Kämpe O, Dobbs K, Delmonte OM, Bacchetta R, Notarangelo LD, Burns JC, Casanova JL, Lionakis MS, Torgerson TR, Anderson MS, DeRisi JL. PMID: 36300623; PMCID: PMC9711525.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    17. Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection. Cell Rep. 2022 10 18; 41(3):111478. VanDyke D, Iglesias M, Tomala J, Young A, Smith J, Perry JA, Gebara E, Cross AR, Cheung LS, Dykema AG, Orcutt-Jahns BT, Henclová T, Golias J, Balolong J, Tomasovic LM, Funda D, Meyer AS, Pardoll DM, Hester J, Issa F, Hunter CA, Anderson MS, Bluestone JA, Raimondi G, Spangler JB. PMID: 36261022; PMCID: PMC9631798.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    18. Publisher Correction: A RORγt+ cell instructs gut microbiota-specific Treg cell differentiation. Nature. 2022 Oct; 610(7931):E7. Kedmi R, Najar TA, Mesa KR, Grayson A, Kroehling L, Hao Y, Hao S, Pokrovskii M, Xu M, Talbot J, Wang J, Germino J, Lareau CA, Satpathy AT, Anderson MS, Laufer TM, Aifantis I, Bartleson JM, Allen PM, Paidassi H, Gardner JM, Stoeckius M, Littman DR. PMID: 36151471.
      View in: PubMed   Mentions:    Fields:    
    19. Immune cells and their inflammatory mediators modify β cells and cause checkpoint inhibitor-induced diabetes. JCI Insight. 2022 09 08; 7(17). Perdigoto AL, Deng S, Du KC, Kuchroo M, Burkhardt DB, Tong A, Israel G, Robert ME, Weisberg SP, Kirkiles-Smith N, Stamatouli AM, Kluger HM, Quandt Z, Young A, Yang ML, Mamula MJ, Pober JS, Anderson MS, Krishnaswamy S, Herold KC. PMID: 35925682; PMCID: PMC9536276.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    20. A RORγt+ cell instructs gut microbiota-specific Treg cell differentiation. Nature. 2022 10; 610(7933):737-743. Kedmi R, Najar TA, Mesa KR, Grayson A, Kroehling L, Hao Y, Hao S, Pokrovskii M, Xu M, Talbot J, Wang J, Germino J, Lareau CA, Satpathy AT, Anderson MS, Laufer TM, Aifantis I, Bartleson JM, Allen PM, Paidassi H, Gardner JM, Stoeckius M, Littman DR. PMID: 36071167; PMCID: PMC9908423.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    21. Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs. Sci Immunol. 2022 Jun 14; eabp8966. Bastard P, Vazquez S, Liu J, Laurie MT, Wang CY, Gervais A, Le Voyer T, Bizien L, Zamecnik C, Philippot Q, Rosain J, Catherinot E, Willmore A, Mitchell AM, Bair R, Garçon P, Kenney H, Fekkar A, Salagianni M, Poulakou G, Siouti E, Sahanic S, Tancevski I, Weiss G, Nagl L, Manry J, Duvlis S, Arroyo-Sánchez D, Paz Artal E, Rubio L, Perani C, Bezzi M, Sottini A, Quaresima V, Roussel L, Vinh DC, Reyes LF, Garzaro M, Hatipoglu N, Boutboul D, Tandjaoui-Lambiotte Y, Borghesi A, Aliberti A, Cassaniti I, Venet F, Monneret G, Halwani R, Sharif-Askari NS, Danielson J, Burrel S, Morbieu C, Stepanovskyy Y, Bondarenko A, Volokha A, Boyarchuk O, Gagro A, Neuville M, Neven B, Keles S, Hernu R, Bal A, Novelli A, Novelli G, Saker K, Ailioaie O, Antolí A, Jeziorski E, Rocamora-Blanch G, Teixeira C, Delaunay C, Lhuillier M, Le Turnier P, Zhang Y, Mahevas M, Pan-Hammarström Q, Abolhassani H, Bompoil T, Dorgham K, COVID HGE consortium † , French COVID study group † , COMET consortium † , Gorochov G, Laouenan C, Rodríguez-Gallego C, Ng LFP, Renia L, Pujol A, Belot A, Raffi F, Allende LM, Martinez-Picado J, Ozcelik T, Keles S, Imberti L, Notarangelo LD, Troya J, Solanich X, Zhang SY, Puel A, Wilson MR, Trouillet-Assant S, Abel L, Jouanguy E, Ye CJ, Cobat A, Thompson LM, Andreakos E, Zhang Q, Anderson MS, Casanova JL, DeRisi JL. PMID: 35857576; PMCID: PMC9210448.
      View in: PubMed   Mentions: 23     Fields:    
    22. The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies. Proc Natl Acad Sci U S A. 2022 05 24; 119(21):e2200413119. Manry J, Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Mégarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs CM, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, Kann NY, Shcherbina A, Lau YL, Leung D, Coulongeat M, Marlet J, Koning R, Reyes LF, Chauvineau-Grenier A, Venet F, Monneret G, Nussenzweig MC, Arrestier R, Boudhabhay I, Baris-Feldman H, Hagin D, Wauters J, Meyts I, Dyer AH, Kennelly SP, Bourke NM, Halwani R, Sharif-Askari FS, Dorgham K, Sallette J, Sedkaoui SM, AlKhater S, Rigo-Bonnin R, Morandeira F, Roussel L, Vinh DC, Erikstrup C, Condino-Neto A, Prando C, Bondarenko A, Spaan AN, Gilardin L, Fellay J, Lyonnet S, Bilguvar K, Lifton RP, Mane S, HGID Lab, COVID Clinicians, COVID-STORM Clinicians, NIAID Immune Response to COVID Group, NH-COVAIR Study Group, Danish CHGE, Danish Blood Donor Study, St. James's Hospital, SARS CoV2 Interest Group, French COVID Cohort Study Group, Imagine COVID-Group, Milieu Intérieur Consortium, CoV-Contact Cohort, Amsterdam UMC Covid-19 Biobank Investigators, COVID Human Genetic Effort, CP-COVID-19 Group, CONSTANCES cohort, 3C-Dijon Study, Cerba Health-Care, Etablissement Français du Sang Study group, Anderson MS, Boisson B, Béziat V, Zhang SY, Andreakos E, Hermine O, Pujol A, Peterson P, Mogensen TH, Rowen L, Mond J, Debette S, de Lamballerie X, Burdet C, Bouadma L, Zins M, Soler-Palacin P, Colobran R, Gorochov G, Solanich X, Susen S, Martinez-Picado J, Raoult D, Vasse M, Gregersen PK, Piemonti L, Rodríguez-Gallego C, Notarangelo LD, Su HC, Kisand K, Okada S, Puel A, Jouanguy E, Rice CM, Tiberghien P, Zhang Q, Casanova JL, Abel L, Cobat A. PMID: 35576468; PMCID: PMC9173764.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    23. Autoantibody discovery across monogenic, acquired, and COVID19-associated autoimmunity with scalable PhIP-Seq. bioRxiv. 2022 Mar 24. Vazquez SE, Mann SA, Bodansky A, Kung AF, Quandt Z, Ferré EMN, Landegren N, Eriksson D, Bastard P, Zhang SY, Liu J, Mitchell A, Mandel-Brehm C, Miao B, Sowa G, Zorn K, Chan AY, Shimizu C, Tremoulet A, Lynch K, Wilson MR, Kampe O, Dobbs K, Delmonte OM, Notarangelo LD, Burns JC, Casanova JL, Lionakis MS, Torgerson TR, Anderson MS, DeRisi JL. PMID: 35350199; PMCID: PMC8963698.
      View in: PubMed   Mentions:
    24. Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM. Nature. 2022 03; 603(7900):321-327. Lanz TV, Brewer RC, Ho PP, Moon JS, Jude KM, Fernandez D, Fernandes RA, Gomez AM, Nadj GS, Bartley CM, Schubert RD, Hawes IA, Vazquez SE, Iyer M, Zuchero JB, Teegen B, Dunn JE, Lock CB, Kipp LB, Cotham VC, Ueberheide BM, Aftab BT, Anderson MS, DeRisi JL, Wilson MR, Bashford-Rogers RJM, Platten M, Garcia KC, Steinman L, Robinson WH. PMID: 35073561; PMCID: PMC9382663.
      View in: PubMed   Mentions: 156     Fields:    Translation:HumansAnimalsCells
    25. Modeling human T1D-associated autoimmune processes. Mol Metab. 2022 02; 56:101417. Khosravi-Maharlooei M, Madley R, Borsotti C, Ferreira LMR, Sharp RC, Brehm MA, Greiner DL, Parent AV, Anderson MS, Sykes M, Creusot RJ. PMID: 34902607; PMCID: PMC8739876.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    26. Single-cell multiomics defines tolerogenic extrathymic Aire-expressing populations with unique homology to thymic epithelium. Sci Immunol. 2021 Nov 12; 6(65):eabl5053. Wang J, Lareau CA, Bautista JL, Gupta AR, Sandor K, Germino J, Yin Y, Arvedson MP, Reeder GC, Cramer NT, Xie F, Ntranos V, Satpathy AT, Anderson MS, Gardner JM. PMID: 34767455; PMCID: PMC8855935.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    27. Response to Comments on "Aberrant type 1 immunity drives susceptibility to mucosal fungal infections". Science. 2021 Sep 17; 373(6561):eabi8835. Break TJ, Oikonomou V, Dutzan N, Desai JV, Swidergall M, Freiwald T, Chauss D, Harrison OJ, Alejo J, Williams DW, Pittaluga S, Lee CR, Bouladoux N, Swamydas M, Hoffman KW, Greenwell-Wild T, Bruno VM, Rosen LB, Lwin W, Renteria A, Pontejo SM, Shannon JP, Myles IA, Olbrich P, Ferré EMN, Schmitt M, Martin D, Genomics and Computational Biology Core16, Barber DL, Solis NV, Notarangelo LD, Serreze DV, Matsumoto M, Hickman HD, Murphy PM, Anderson MS, Lim JK, Holland SM, Filler SG, Afzali B, Belkaid Y, Moutsopoulos NM, Lionakis MS. PMID: 34529475; PMCID: PMC10120387.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
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    33. A human mutation in STAT3 promotes type 1 diabetes through a defect in CD8+ T cell tolerance. J Exp Med. 2021 08 02; 218(8). Warshauer JT, Belk JA, Chan AY, Wang J, Gupta AR, Shi Q, Skartsis N, Peng Y, Phipps JD, Acenas D, Smith JA, Tamaki SJ, Tang Q, Gardner JM, Satpathy AT, Anderson MS. PMID: 34115115; PMCID: PMC8203485.
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    39. More on STAT1 Gain of Function, Type 1 Diabetes, and JAK Inhibition. Reply. N Engl J Med. 2021 01 07; 384(1):93-94. Anderson MS, Chaimowitz NS, Forbes LR. PMID: 33406352.
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    128. An aberrant prostate antigen-specific immune response causes prostatitis in mice and is associated with chronic prostatitis in humans. J Clin Invest. 2009 Jul; 119(7):2031-41. Hou Y, DeVoss J, Dao V, Kwek S, Simko JP, McNeel DG, Anderson MS, Fong L. PMID: 19603556; PMCID: PMC2701875.
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    129. Monogenic autoimmune diseases: insights into self-tolerance. Pediatr Res. 2009 May; 65(5 Pt 2):20R-25R. Su MA, Anderson MS. PMID: 19190526; PMCID: PMC2951117.
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    130. A novel myelin P0-specific T cell receptor transgenic mouse develops a fulminant autoimmune peripheral neuropathy. J Exp Med. 2009 Mar 16; 206(3):507-14. Louvet C, Kabre BG, Davini DW, Martinier N, Su MA, DeVoss JJ, Rosenthal WL, Anderson MS, Bour-Jordan H, Bluestone JA. PMID: 19221395; PMCID: PMC2699118.
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    131. The role of X-linked FOXP3 in the autoimmune susceptibility of Turner Syndrome patients. Clin Immunol. 2009 Apr; 131(1):139-44. Su MA, Stenerson M, Liu W, Putnam A, Conte F, Bluestone JA, Anderson MS. PMID: 19150256; PMCID: PMC2949956.
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    132. Update in endocrine autoimmunity. J Clin Endocrinol Metab. 2008 Oct; 93(10):3663-70. Anderson MS. PMID: 18842982; PMCID: PMC2579640.
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    133. Effector mechanisms of the autoimmune syndrome in the murine model of autoimmune polyglandular syndrome type 1. J Immunol. 2008 Sep 15; 181(6):4072-9. Devoss JJ, Shum AK, Johannes KP, Lu W, Krawisz AK, Wang P, Yang T, Leclair NP, Austin C, Strauss EC, Anderson MS. PMID: 18768863; PMCID: PMC2556863.
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    134. Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity. J Exp Med. 2008 Sep 01; 205(9):1983-91. Zhou X, Jeker LT, Fife BT, Zhu S, Anderson MS, McManus MT, Bluestone JA. PMID: 18725525; PMCID: PMC2526194.
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    135. Deletional tolerance mediated by extrathymic Aire-expressing cells. Science. 2008 Aug 08; 321(5890):843-7. Gardner JM, Devoss JJ, Friedman RS, Wong DJ, Tan YX, Zhou X, Johannes KP, Su MA, Chang HY, Krummel MF, Anderson MS. PMID: 18687966; PMCID: PMC2532844.
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    136. Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire. J Clin Invest. 2008 May; 118(5):1712-26. Su MA, Giang K, Zumer K, Jiang H, Oven I, Rinn JL, Devoss JJ, Johannes KP, Lu W, Gardner J, Chang A, Bubulya P, Chang HY, Peterlin BM, Anderson MS. PMID: 18414681; PMCID: PMC2293336.
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    137. Expression of Aire and the early wave of apoptosis in spermatogenesis. J Immunol. 2008 Feb 01; 180(3):1338-43. Schaller CE, Wang CL, Beck-Engeser G, Goss L, Scott HS, Anderson MS, Wabl M. PMID: 18209027.
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    138. Small proline-rich protein 1B (SPRR1B) is a biomarker for squamous metaplasia in dry eye disease. Invest Ophthalmol Vis Sci. 2008 Jan; 49(1):34-41. Li S, Nikulina K, DeVoss J, Wu AJ, Strauss EC, Anderson MS, McNamara NA. PMID: 18172072; PMCID: PMC2574421.
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    139. A robust immunoassay for anti-interferon autoantibodies that is highly specific for patients with autoimmune polyglandular syndrome type 1. Clin Immunol. 2007 Nov; 125(2):131-7. Zhang L, Barker JM, Babu S, Su M, Stenerson M, Cheng M, Shum A, Zamir E, Badolato R, Law A, Eisenbarth GS, Anderson MS. PMID: 17825626; PMCID: PMC2080870.
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    140. What's new in the Aire? Trends Immunol. 2007 Jul; 28(7):321-7. Cheng MH, Shum AK, Anderson MS. PMID: 17556019.
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    141. Lessons on immune tolerance from the monogenic disease APS1. Curr Opin Genet Dev. 2007 Jun; 17(3):193-200. DeVoss JJ, Anderson MS. PMID: 17466510.
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    142. Spontaneous autoimmunity prevented by thymic expression of a single self-antigen. J Exp Med. 2006 Nov 27; 203(12):2727-35. DeVoss J, Hou Y, Johannes K, Lu W, Liou GI, Rinn J, Chang H, Caspi RR, Caspi R, Fong L, Anderson MS. PMID: 17116738; PMCID: PMC2118158.
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    143. Modifier loci condition autoimmunity provoked by Aire deficiency. J Exp Med. 2005 Sep 19; 202(6):805-15. Jiang W, Anderson MS, Bronson R, Mathis D, Benoist C. PMID: 16172259; PMCID: PMC2212943.
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    144. The cellular mechanism of Aire control of T cell tolerance. Immunity. 2005 Aug; 23(2):227-39. Anderson MS, Venanzi ES, Chen Z, Berzins SP, Benoist C, Mathis D. PMID: 16111640.
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    145. The NOD mouse: a model of immune dysregulation. Annu Rev Immunol. 2005; 23:447-85. Anderson MS, Bluestone JA. PMID: 15771578.
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    146. Aire: an update. Curr Opin Immunol. 2004 Dec; 16(6):746-52. Su MA, Anderson MS. PMID: 15511668.
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    147. Enhanced antigen presentation in the absence of the invariant chain endosomal localization signal. J Exp Med. 1993 Dec 01; 178(6):1959-69. Anderson MS, Swier K, Arneson L, Miller J. PMID: 7902408; PMCID: PMC2191285.
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    148. Invariant chain can function as a chaperone protein for class II major histocompatibility complex molecules. Proc Natl Acad Sci U S A. 1992 Mar 15; 89(6):2282-6. Anderson MS, Miller J. PMID: 1549594; PMCID: PMC48641.
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