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    Rachel Whitmer, PhD

    TitleAssociate Professor
    SchoolUCSF School of Medicine
    DepartmentEpidemiology & Biostatistics
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Dacks PA, Armstrong JJ, Brannan SK, Carman AJ, Green AM, Kirkman MS, Krakoff LR, Kuller LH, Launer LJ, Lovestone S, Merikle E, Neumann PJ, Rockwood K, Shineman DW, Stefanacci RG, Velentgas P, Viswanathan A, Whitmer RA, Williamson JD, Fillit HM. A call for comparative effectiveness research to learn whether routine clinical care decisions can protect from dementia and cognitive decline. Alzheimers Res Ther. 2016; 8:33. PMID: 27543171.
        View in: PubMed
      2. Rist PM, Nguyen TT, Whitmer RA, Glymour MM. Modifiable risk factors for nursing home admission among individuals with high and low dementia risk. Arch Gerontol Geriatr. 2016 Jul-Aug; 65:140-5. PMID: 27023177.
        View in: PubMed
      3. Albanese E, Matthews KA, Zhang J, Jacobs DR, Whitmer RA, Wadley VG, Yaffe K, Sidney S, Launer LJ. Hostile attitudes and effortful coping in young adulthood predict cognition 25 years later. Neurology. 2016 Mar 29; 86(13):1227-34. PMID: 26935891.
        View in: PubMed
      4. Auer R, Vittinghoff E, Yaffe K, Künzi A, Kertesz SG, Levine DA, Albanese E, Whitmer RA, Jacobs DR, Sidney S, Glymour MM, Pletcher MJ. Association Between Lifetime Marijuana Use and Cognitive Function in Middle Age: The Coronary Artery Risk Development in Young Adults (CARDIA) Study. JAMA Intern Med. 2016 Mar 1; 176(3):352-61. PMID: 26831916.
        View in: PubMed
      5. Barone FC, Gustafson D, Crystal HA, Moreno H, Adamski MG, Arai K, Baird AE, Balucani C, Brickman AM, Cechetto D, Gorelick P, Biessels GJ, Kiliaan A, Launer L, Schneider J, Sorond FA, Whitmer R, Wright C, Zhang ZG. First translational 'Think Tank' on cerebrovascular disease, cognitive impairment and dementia. J Transl Med. 2016; 14(1):50. PMID: 26873444.
        View in: PubMed
      6. Mayeda ER, Glymour MM, Quesenberry CP, Whitmer RA. Inequalities in dementia incidence between six racial and ethnic groups over 14 years. Alzheimers Dement. 2016 Mar; 12(3):216-24. PMID: 26874595.
        View in: PubMed
      7. Hoang TD, Reis J, Zhu N, Jacobs DR, Launer LJ, Whitmer RA, Sidney S, Yaffe K. Effect of Early Adult Patterns of Physical Activity and Television Viewing on Midlife Cognitive Function. JAMA Psychiatry. 2016 Jan 1; 73(1):73-9. PMID: 26629780.
        View in: PubMed
      8. Banda Y, Kvale MN, Hoffmann TJ, Hesselson SE, Ranatunga D, Tang H, Sabatti C, Croen LA, Dispensa BP, Henderson M, Iribarren C, Jorgenson E, Kushi LH, Ludwig D, Olberg D, Quesenberry CP, Rowell S, Sadler M, Sakoda LC, Sciortino S, Shen L, Smethurst D, Somkin CP, Van Den Eeden SK, Walter L, Whitmer RA, Kwok PY, Schaefer C, Risch N. Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort. Genetics. 2015 Aug; 200(4):1285-95. PMID: 26092716; PMCID: PMC4574246 [Available on 08/01/16].
      9. Lapham K, Kvale MN, Lin J, Connell S, Croen LA, Dispensa BP, Fang L, Hesselson S, Hoffmann TJ, Iribarren C, Jorgenson E, Kushi LH, Ludwig D, Matsuguchi T, McGuire WB, Miles S, Quesenberry CP, Rowell S, Sadler M, Sakoda LC, Smethurst D, Somkin CP, Van Den Eeden SK, Walter L, Whitmer RA, Kwok PY, Risch N, Schaefer C, Blackburn EH. Automated Assay of Telomere Length Measurement and Informatics for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort. Genetics. 2015 Aug; 200(4):1061-72. PMID: 26092717; PMCID: PMC4574243 [Available on 08/01/16].
      10. Kvale MN, Hesselson S, Hoffmann TJ, Cao Y, Chan D, Connell S, Croen LA, Dispensa BP, Eshragh J, Finn A, Gollub J, Iribarren C, Jorgenson E, Kushi LH, Lao R, Lu Y, Ludwig D, Mathauda GK, McGuire WB, Mei G, Miles S, Mittman M, Patil M, Quesenberry CP, Ranatunga D, Rowell S, Sadler M, Sakoda LC, Shapero M, Shen L, Shenoy T, Smethurst D, Somkin CP, Van Den Eeden SK, Walter L, Wan E, Webster T, Whitmer RA, Wong S, Zau C, Zhan Y, Schaefer C, Kwok PY, Risch N. Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort. Genetics. 2015 Aug; 200(4):1051-60. PMID: 26092718; PMCID: PMC4574249 [Available on 08/01/16].
      11. Zhu N, Jacobs DR, Schreiner PJ, Launer LJ, Whitmer RA, Sidney S, Demerath E, Thomas W, Bouchard C, He K, Erus G, Battapady H, Bryan RN. Cardiorespiratory fitness and brain volume and white matter integrity: The CARDIA Study. Neurology. 2015 Jun 9; 84(23):2347-53. PMID: 25957331; PMCID: PMC4464743 [Available on 06/09/16].
      12. Karter AJ, Laiteerapong N, Chin MH, Moffet HH, Parker MM, Sudore R, Adams AS, Schillinger D, Adler NS, Whitmer RA, Piette JD, Huang ES. Ethnic Differences in Geriatric Conditions and Diabetes Complications Among Older, Insured Adults With Diabetes: The Diabetes and Aging Study. J Aging Health. 2015 Aug; 27(5):894-918. PMID: 25659747; PMCID: PMC4498983 [Available on 02/01/16].
      13. Zhu N, Jacobs DR, Meyer KA, He K, Launer L, Reis JP, Yaffe K, Sidney S, Whitmer RA, Steffen LM. Cognitive function in a middle aged cohort is related to higher quality dietary pattern 5 and 25 years earlier: the CARDIA study. J Nutr Health Aging. 2015 Jan; 19(1):33-8. PMID: 25560814.
        View in: PubMed
      14. Mayeda ER, Whitmer RA, Yaffe K. Diabetes and cognition. Clin Geriatr Med. 2015 Feb; 31(1):101-15, ix. PMID: 25453304; PMCID: PMC4370221 [Available on 02/01/16].
      15. Whitmer RA. Cognitive impairment in ORIGIN: timing is everything. Lancet Diabetes Endocrinol. 2014 Jul; 2(7):531-2. PMID: 24898832.
        View in: PubMed
      16. Zhu N, Jacobs DR, Schreiner PJ, Yaffe K, Bryan N, Launer LJ, Whitmer RA, Sidney S, Demerath E, Thomas W, Bouchard C, He K, Reis J, Sternfeld B. Cardiorespiratory fitness and cognitive function in middle age: the CARDIA study. Neurology. 2014 Apr 15; 82(15):1339-46. PMID: 24696506; PMCID: PMC4001190.
      17. Yaffe K, Vittinghoff E, Pletcher MJ, Hoang TD, Launer LJ, Whitmer R, Coker LH, Sidney S. Early adult to midlife cardiovascular risk factors and cognitive function. Circulation. 2014 Apr 15; 129(15):1560-7. PMID: 24687777.
        View in: PubMed
      18. Exalto LG, Biessels GJ, Karter AJ, Huang ES, Quesenberry CP, Whitmer RA. Severe diabetic retinal disease and dementia risk in type 2 diabetes. J Alzheimers Dis. 2014; 42 Suppl 3:S109-17. PMID: 24625797; PMCID: PMC4373321.
      19. Mayeda ER, Karter AJ, Huang ES, Moffet HH, Haan MN, Whitmer RA. Racial/ethnic differences in dementia risk among older type 2 diabetic patients: the diabetes and aging study. Diabetes Care. 2014 Apr; 37(4):1009-15. PMID: 24271192; PMCID: PMC3964496.
      20. Biessels GJ, Strachan MW, Visseren FL, Kappelle LJ, Whitmer RA. Dementia and cognitive decline in type 2 diabetes and prediabetic stages: towards targeted interventions. Lancet Diabetes Endocrinol. 2014 Mar; 2(3):246-55. PMID: 24622755.
        View in: PubMed
      21. Exalto LG, Quesenberry CP, Barnes D, Kivipelto M, Biessels GJ, Whitmer RA. Midlife risk score for the prediction of dementia four decades later. Alzheimers Dement. 2014 Sep; 10(5):562-70. PMID: 24035147.
        View in: PubMed
      22. Exalto LG, Biessels GJ, Karter AJ, Huang ES, Katon WJ, Minkoff JR, Whitmer RA. Risk score for prediction of 10 year dementia risk in individuals with type 2 diabetes: a cohort study. Lancet Diabetes Endocrinol. 2013 Nov; 1(3):183-90. PMID: 24622366; PMCID: PMC4429783.
      23. Whitmer RA, Kushi LH. Commentary: Mediterranean diet and cognitive function: are we approaching clarity in this area? Epidemiology. 2013 Jul; 24(4):500-2. PMID: 23732732.
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      24. Shao H, Breitner JC, Whitmer RA, Wang J, Hayden K, Wengreen H, Corcoran C, Tschanz J, Norton M, Munger R, Welsh-Bohmer K, Zandi PP. Hormone therapy and Alzheimer disease dementia: new findings from the Cache County Study. Neurology. 2012 Oct 30; 79(18):1846-52. PMID: 23100399; PMCID: PMC3525314.
      25. Exalto LG, Whitmer RA, Kappele LJ, Biessels GJ. An update on type 2 diabetes, vascular dementia and Alzheimer's disease. Exp Gerontol. 2012 Nov; 47(11):858-64. PMID: 22884853.
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      26. Sudore RL, Karter AJ, Huang ES, Moffet HH, Laiteerapong N, Schenker Y, Adams A, Whitmer RA, Liu JY, Miao Y, John PM, Schillinger D. Symptom burden of adults with type 2 diabetes across the disease course: diabetes & aging study. J Gen Intern Med. 2012 Dec; 27(12):1674-81. PMID: 22854982; PMCID: PMC3509316.
      27. Zeki Al Hazzouri A, Haan MN, Whitmer RA, Yaffe K, Neuhaus J. Central obesity, leptin and cognitive decline: the Sacramento Area Latino Study on Aging. Dement Geriatr Cogn Disord. 2012; 33(6):400-9. PMID: 22814127; PMCID: PMC3483312.
      28. Barnes DE, Yaffe K, Byers AL, McCormick M, Schaefer C, Whitmer RA. Midlife vs late-life depressive symptoms and risk of dementia: differential effects for Alzheimer disease and vascular dementia. Arch Gen Psychiatry. 2012 May; 69(5):493-8. PMID: 22566581; PMCID: PMC3704214.
      29. Katon W, Lyles CR, Parker MM, Karter AJ, Huang ES, Whitmer RA. Association of depression with increased risk of dementia in patients with type 2 diabetes: the Diabetes and Aging Study. Arch Gen Psychiatry. 2012 Apr; 69(4):410-7. PMID: 22147809; PMCID: PMC3558525.
      30. Hoffmann TJ, Zhan Y, Kvale MN, Hesselson SE, Gollub J, Iribarren C, Lu Y, Mei G, Purdy MM, Quesenberry C, Rowell S, Shapero MH, Smethurst D, Somkin CP, Van den Eeden SK, Walter L, Webster T, Whitmer RA, Finn A, Schaefer C, Kwok PY, Risch N. Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm. Genomics. 2011 Dec; 98(6):422-30. PMID: 21903159; PMCID: PMC3502750.
      31. Hoffmann TJ, Kvale MN, Hesselson SE, Zhan Y, Aquino C, Cao Y, Cawley S, Chung E, Connell S, Eshragh J, Ewing M, Gollub J, Henderson M, Hubbell E, Iribarren C, Kaufman J, Lao RZ, Lu Y, Ludwig D, Mathauda GK, McGuire W, Mei G, Miles S, Purdy MM, Quesenberry C, Ranatunga D, Rowell S, Sadler M, Shapero MH, Shen L, Shenoy TR, Smethurst D, Van den Eeden SK, Walter L, Wan E, Wearley R, Webster T, Wen CC, Weng L, Whitmer RA, Williams A, Wong SC, Zau C, Finn A, Schaefer C, Kwok PY, Risch N. Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array. Genomics. 2011 Aug; 98(2):79-89. PMID: 21565264; PMCID: PMC3146553.
      32. Whitmer RA, Quesenberry CP, Zhou J, Yaffe K. Timing of hormone therapy and dementia: the critical window theory revisited. Ann Neurol. 2011 Jan; 69(1):163-9. PMID: 21280086; PMCID: PMC3058824.
      33. Rusanen M, Kivipelto M, Quesenberry CP, Zhou J, Whitmer RA. Heavy smoking in midlife and long-term risk of Alzheimer disease and vascular dementia. Arch Intern Med. 2011 Feb 28; 171(4):333-9. PMID: 20975015.
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      34. Barnes DE, Covinsky KE, Whitmer RA, Kuller LH, Lopez OL, Yaffe K. Commentary on "Developing a national strategy to prevent dementia: Leon Thal Symposium 2009." Dementia risk indices: A framework for identifying individuals with a high dementia risk. Alzheimers Dement. 2010 Mar; 6(2):138-41. PMID: 20298975; PMCID: PMC2909695.
      35. Li NC, Lee A, Whitmer RA, Kivipelto M, Lawler E, Kazis LE, Wolozin B. Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: prospective cohort analysis. BMJ. 2010; 340:b5465. PMID: 20068258; PMCID: PMC2806632.
      36. Solomon A, Kivipelto M, Wolozin B, Zhou J, Whitmer RA. Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later. Dement Geriatr Cogn Disord. 2009; 28(1):75-80. PMID: 19648749; PMCID: PMC2814023.
      37. Barnes DE, Covinsky KE, Whitmer RA, Kuller LH, Lopez OL, Yaffe K. Predicting risk of dementia in older adults: The late-life dementia risk index. Neurology. 2009 Jul 21; 73(3):173-9. PMID: 19439724; PMCID: PMC2715571.
      38. Bennett DA, Whitmer RA. NSAID exposure and risk of Alzheimer disease: is timing everything? Neurology. 2009 Jun 2; 72(22):1884-5. PMID: 19386996.
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      39. Whitmer RA, Karter AJ, Yaffe K, Quesenberry CP, Selby JV. Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus. JAMA. 2009 Apr 15; 301(15):1565-72. PMID: 19366776; PMCID: PMC2782622.
      40. Whitmer RA, Gustafson DR, Barrett-Connor E, Haan MN, Gunderson EP, Yaffe K. Central obesity and increased risk of dementia more than three decades later. Neurology. 2008 Sep 30; 71(14):1057-64. PMID: 18367704.
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      41. Gunderson EP, Sternfeld B, Wellons MF, Whitmer RA, Chiang V, Quesenberry CP, Lewis CE, Sidney S. Childbearing may increase visceral adipose tissue independent of overall increase in body fat. Obesity (Silver Spring). 2008 May; 16(5):1078-84. PMID: 18356843; PMCID: PMC2952441.
      42. Flick ED, Habel LA, Chan KA, Van Den Eeden SK, Quinn VP, Haque R, Orav EJ, Seeger JD, Sadler MC, Quesenberry CP, Sternfeld B, Jacobsen SJ, Whitmer RA, Caan BJ. Statin use and risk of prostate cancer in the California Men's Health Study cohort. Cancer Epidemiol Biomarkers Prev. 2007 Nov; 16(11):2218-25. PMID: 17971519.
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      43. Whitmer RA. Type 2 diabetes and risk of cognitive impairment and dementia. Curr Neurol Neurosci Rep. 2007 Sep; 7(5):373-80. PMID: 17764626.
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      44. Yaffe K, Haan M, Blackwell T, Cherkasova E, Whitmer RA, West N. Metabolic syndrome and cognitive decline in elderly Latinos: findings from the Sacramento Area Latino Study of Aging study. J Am Geriatr Soc. 2007 May; 55(5):758-62. PMID: 17493197.
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      45. Whitmer RA, Gunderson EP, Quesenberry CP, Zhou J, Yaffe K. Body mass index in midlife and risk of Alzheimer disease and vascular dementia. Curr Alzheimer Res. 2007 Apr; 4(2):103-9. PMID: 17430231.
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      46. Whitmer RA. The epidemiology of adiposity and dementia. Curr Alzheimer Res. 2007 Apr; 4(2):117-22. PMID: 17430233.
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      47. Gunderson EP, Lewis CE, Wei GS, Whitmer RA, Quesenberry CP, Sidney S. Lactation and changes in maternal metabolic risk factors. Obstet Gynecol. 2007 Mar; 109(3):729-38. PMID: 17329527; PMCID: PMC2930880.
      48. Haan MN, Miller JW, Aiello AE, Whitmer RA, Jagust WJ, Mungas DM, Allen LH, Green R. Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on Aging. Am J Clin Nutr. 2007 Feb; 85(2):511-7. PMID: 17284751; PMCID: PMC1892349.
      49. Barnes DE, Whitmer RA, Yaffe K. Physical activity and dementia: The need for prevention trials. Exerc Sport Sci Rev. 2007 Jan; 35(1):24-9. PMID: 17211190.
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      50. Elkins JS, Whitmer RA, Sidney S, Sorel M, Yaffe K, Johnston SC. Midlife obesity and long-term risk of nursing home admission. Obesity (Silver Spring). 2006 Aug; 14(8):1472-8. PMID: 16988091.
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      51. Yaffe K, Blackwell T, Whitmer RA, Krueger K, Barrett Connor E. Glycosylated hemoglobin level and development of mild cognitive impairment or dementia in older women. J Nutr Health Aging. 2006 Jul-Aug; 10(4):293-5. PMID: 16886099.
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      52. Gunderson EP, Whitmer RA, Lewis CE, Quesenberry CP, West DS, Sidney S. Do long-term HDL-C declines associated with a first birth vary by apo E phenotype? The Coronary Artery Risk Development in Young Adults (CARDIA) study. J Womens Health (Larchmt). 2005 Dec; 14(10):917-28. PMID: 16372893; PMCID: PMC3146172.
      53. Whitmer RA, Gunderson EP, Barrett-Connor E, Quesenberry CP, Yaffe K. Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study. BMJ. 2005 Jun 11; 330(7504):1360. PMID: 15863436; PMCID: PMC558283.
      54. Whitmer RA, Sidney S, Selby J, Johnston SC, Yaffe K. Midlife cardiovascular risk factors and risk of dementia in late life. Neurology. 2005 Jan 25; 64(2):277-81. PMID: 15668425.
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      55. Whitmer RA, Haan MN, Miller JW, Yaffe K. Hormone replacement therapy and cognitive performance: the role of homocysteine. J Gerontol A Biol Sci Med Sci. 2003 Apr; 58(4):324-30. PMID: 12663696.
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      56. Robbins J, Hirsch C, Whitmer R, Cauley J, Harris T. The association of bone mineral density and depression in an older population. J Am Geriatr Soc. 2001 Jun; 49(6):732-6. PMID: 11454111.
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      57. Whitmer RA, Whitbourne SK. Evaluation of infantilizing speech in a rehabilitation setting: relation to age. Int J Aging Hum Dev. 1997; 44(2):129-36. PMID: 9169315.
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