Liusheng Huang, PhD

Title(s)Co-Dir, Drug Research Unit, Clinical Pharmacy
SchoolSchool of Pharmacy
Address2540 23rd Street, #2804
San Francisco CA 94110
ORCID ORCID Icon0000-0003-2702-4486 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Francisco, San FranciscoPostdoctoral Studies04/2007Pharmaceutical Chemistry
    Wayne State University, DetroitPh.D02/2003Pharmaceutical Sciences
    Peking Union Medical College, BeijingMS07/1998Medicinal Chemistry
    Beijing Medical University, BeijingBS07/1992Pharmaceutical Sciences/Medicinal Chemistry

    Collapse Overview 

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Determination of sulfadoxine and pyrimethamine in microvolume human plasma using ultra high performance liquid chromatography-tandam mass spectrometry. Journal of Chromatography B. 2024 Jan 1; 124030. Sok SV, Marzan MF, Roh RM, Guo GK, Legac LJ, Mwebaza MN, Dorsey DG, Rosenthal RP, Aweeka AF, Huang HL. .
      View in: Publisher Site   Mentions:
    2. Pharmacokinetics (PK) of Deferasirox in Transfusion Dependent Thalassemia. Blood. 2023 Nov 28; 142(Supplement 1):5248. Winger WB, Usac UF, Huang HL, Lal LA, Long-Boyle LJ. .
      View in: Publisher Site   Mentions:
    3. Efavirenz-Based Antiretroviral Therapy but Not Pregnancy Increased Unbound Piperaquine Exposure in Women during Malaria Chemoprevention. Antimicrob Agents Chemother. 2023 04 18; 67(4):e0142722. Hong H, Aslam-Mir U, Kajubi R, Wallender E, Mwebaza N, Dorsey G, Rosenthal PJ, Aweeka FT, Huang L. PMID: 36916944; PMCID: PMC10112216.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. The Impact of Extended Treatment With Artemether-lumefantrine on Antimalarial Exposure and Reinfection Risks in Ugandan Children With Uncomplicated Malaria: A Randomized Controlled Trial. Clin Infect Dis. 2023 02 08; 76(3):443-452. Whalen ME, Kajubi R, Goodwin J, Orukan F, Colt M, Huang L, Richards K, Wang K, Li F, Mwebaza N, Aweeka FT, Parikh S. PMID: 36130191; PMCID: PMC9907485.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    5. Prospective Validation and Refinement of a Population Pharmacokinetic Model of Fludarabine in Children and Young Adults Undergoing Hematopoietic Cell Transplantation. Pharmaceutics. 2022 Nov 15; 14(11). Brooks JT, Solans BP, Lu Y, Kharbanda S, Dvorak CC, Lalefar N, Long S, Gupta AO, Horn B, Lamba JK, Huang L, Apsel-Winger B, Keizer RJ, Savic R, Long-Boyle J. PMID: 36432661.
      View in: PubMed   Mentions:
    6. Impact of Drug Exposure on Resistance Selection Following Artemether-Lumefantrine Treatment for Malaria in Children With and Without HIV in Uganda. Clin Pharmacol Ther. 2023 03; 113(3):660-669. Kay K, Goodwin J, Ehrlich H, Ou J, Freeman T, Wang K, Li F, Wade M, French J, Huang L, Aweeka F, Mwebaza N, Kajubi R, Riggs M, Ruiz-Garcia A, Parikh S. PMID: 36260349; PMCID: PMC9981240.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    7. Quantification of N, N' N"-triethylenethiophosphoramide, N, N"-triethylenephosphoramide, cyclophosphamide, and 4-hydroxy-cyclophosphamide in microvolume human plasma to support neonatal and pediatric drug studies. J Chromatogr Open. 2022 Nov; 2. Huang L, Winger BA, Cheah V, Gingrich D, Marzan F, Lu Y, Cooper JC, Aweeka F, Long-Boyle J. PMID: 35875822; PMCID: PMC9302610.
      View in: PubMed   Mentions:
    8. Determination of unbound piperaquine in human plasma by ultra-high performance liquid chromatography tandem mass spectrometry. J Chromatogr Open. 2022 Nov; 2. Huang L, Sok V, Aslam-Mir U, Marzan F, Whalen M, Rosenthal PJ, Aweeka F. PMID: 35531322; PMCID: PMC9068709.
      View in: PubMed   Mentions: 2  
    9. Differential toxicity to murine small and large intestinal epithelium induced by oncology drugs. Commun Biol. 2022 01 27; 5(1):99. Bieber JM, Sanman LE, Sun X, Hammerlindl H, Bao F, Roth MA, Koleske ML, Huang L, Aweeka F, Wu LF, Altschuler SJ. PMID: 35087225; PMCID: PMC8795448.
      View in: PubMed   Mentions: 1  Translation:AnimalsCells
    10. Loss of GdpP Function in Staphylococcus aureus Leads to β-Lactam Tolerance and Enhanced Evolution of β-Lactam Resistance. Antimicrob Agents Chemother. 2022 02 15; 66(2):e0143121. Poon R, Basuino L, Satishkumar N, Chatterjee A, Mukkayyan N, Buggeln E, Huang L, Nair V, Argudín MA, Datta SK, Chambers HF, Chatterjee SS. PMID: 34843389; PMCID: PMC8846394.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    11. Identifying an optimal dihydroartemisinin-piperaquine dosing regimen for malaria prevention in young Ugandan children. Nat Commun. 2021 11 18; 12(1):6714. Wallender E, Ali AM, Hughes E, Kakuru A, Jagannathan P, Muhindo MK, Opira B, Whalen M, Huang L, Duvalsaint M, Legac J, Kamya MR, Dorsey G, Aweeka F, Rosenthal PJ, Savic RM. PMID: 34795281; PMCID: PMC8602248.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    12. Development and validation of an LC-MS/MS method for determination of hydroxychloroquine, its two metabolites, and azithromycin in EDTA-treated human plasma. PLoS One. 2021; 16(3):e0247356. Sok V, Marzan F, Gingrich D, Aweeka F, Huang L. PMID: 33667247; PMCID: PMC7935301.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    13. Methotrexate Decreases Tenofovir Exposure in Antiretroviral-Suppressed Individuals Living With HIV. J Acquir Immune Defic Syndr. 2020 12 15; 85(5):651-658. Gingrich D, Deitchman AN, Kantor A, Huang L, Stein JH, Currier JS, Hsue PY, Ribaudo HJ, Aweeka FT, ACTG 5314 Protocol Team. PMID: 33177476; PMCID: PMC8132144.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    14. Piperaquine Exposure Is Altered by Pregnancy, HIV, and Nutritional Status in Ugandan Women. Antimicrob Agents Chemother. 2020 11 17; 64(12). Hughes E, Imperial M, Wallender E, Kajubi R, Huang L, Jagannathan P, Zhang N, Kakuru A, Natureeba P, Mwima MW, Muhindo M, Mwebaza N, Clark TD, Opira B, Nakalembe M, Havlir D, Kamya M, Rosenthal PJ, Dorsey G, Aweeka F, Savic RM. PMID: 33020153; PMCID: PMC7674024.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    15. Therapeutic Efficacy of Artemether-Lumefantrine for Uncomplicated Falciparum Malaria in Northern Zambia. Am J Trop Med Hyg. 2020 12; 103(6):2224-2232. Ippolito MM, Pringle JC, Siame M, Katowa B, Aydemir O, Oluoch PO, Huang L, Aweeka FT, Bailey JA, Juliano JJ, Meshnick SR, Shapiro TA, Moss WJ, Thuma PE. PMID: 33078701; PMCID: PMC7695049.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    16. Determination of piperaquine concentration in human plasma and the correlation of capillary versus venous plasma concentrations. PLoS One. 2020; 15(5):e0233893. Mwebaza N, Cheah V, Forsman C, Kajubi R, Marzan F, Wallender E, Dorsey G, Rosenthal PJ, Aweeka F, Huang L. PMID: 32470030; PMCID: PMC7259774.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    17. Efavirenz-Based Antiretroviral Therapy Reduces Artemether-Lumefantrine Exposure for Malaria Treatment in HIV-Infected Pregnant Women. J Acquir Immune Defic Syndr. 2020 02 01; 83(2):140-147. Hughes E, Mwebaza N, Huang L, Kajubi R, Nguyen V, Nyunt MM, Orukan F, Mwima MW, Parikh S, Aweeka F. PMID: 31929402; PMCID: PMC7061940.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    18. Reduced Exposure to Piperaquine, Compared to Adults, in Young Children Receiving Dihydroartemisinin-Piperaquine as Malaria Chemoprevention. Clin Pharmacol Ther. 2019 12; 106(6):1310-1318. Whalen ME, Kajubi R, Chamankhah N, Huang L, Orukan F, Wallender E, Kamya MR, Dorsey G, Jagannathan P, Rosenthal PJ, Mwebaza N, Aweeka FT. PMID: 31173649; PMCID: PMC6851416.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Population Pharmacokinetics of Clofarabine as Part of Pretransplantation Conditioning in Pediatric Subjects before Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant. 2019 08; 25(8):1603-1610. Wang H, Jones AK, Dvorak CC, Huang L, Orchard P, Ivaturi V, Long-Boyle J. PMID: 31002993; PMCID: PMC10291704.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    20. Determination of melphalan in human plasma by UPLC-UV method. Cancer Chemother Pharmacol. 2019 05; 83(5):905-910. Huang L, Cheah V, Chan D, Marzan F, Dvorak CC, Aweeka FT, Long-Boyle J. PMID: 30847504; PMCID: PMC6490959.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Intermittent Preventive Treatment for Malaria in Pregnancy: Optimization of Target Concentrations of Dihydroartemisinin-Piperaquine. Clin Infect Dis. 2018 09 14; 67(7):1079-1088. Savic RM, Jagannathan P, Kajubi R, Huang L, Zhang N, Were M, Kakuru A, Muhindo MK, Mwebaza N, Wallender E, Clark TD, Opira B, Kamya M, Havlir DV, Rosenthal PJ, Dorsey G, Aweeka FT. PMID: 29547881; PMCID: PMC6137112.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    22. Strong correlation of lumefantrine concentrations in capillary and venous plasma from malaria patients. PLoS One. 2018; 13(8):e0202082. Huang L, Mwebaza N, Kajubi R, Marzan F, Forsman C, Parikh S, Aweeka FT. PMID: 30114201; PMCID: PMC6095545.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    23. Determination of Tobramycin in M9 Medium by LC-MS/MS: Signal Enhancement by Trichloroacetic Acid. J Anal Methods Chem. 2018; 2018:7965124. Huang L, Haagensen JAJ, Verotta D, Cheah V, Spormann AM, Aweeka F, Yang K. PMID: 29854560; PMCID: PMC5944200.
      View in: PubMed   Mentions:
    24. Semi-quantitative measurement of the antimalarial lumefantrine from untreated dried blood spots using LC-MS/MS. J Pharm Biomed Anal. 2018 Jun 05; 155:241-246. Ippolito MM, Huang L, Siame M, Thuma P, Shapiro TA, Aweeka FT. PMID: 29655094; PMCID: PMC5949273.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    25. Predicting Optimal Dihydroartemisinin-Piperaquine Regimens to Prevent Malaria During Pregnancy for Human Immunodeficiency Virus-Infected Women Receiving Efavirenz. J Infect Dis. 2018 03 05; 217(6):964-972. Wallender E, Vucicevic K, Jagannathan P, Huang L, Natureeba P, Kakuru A, Muhindo M, Nakalembe M, Havlir D, Kamya M, Aweeka F, Dorsey G, Rosenthal PJ, Savic RM. PMID: 29272443; PMCID: PMC5853566.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    26. Spatiotemporal pharmacodynamics of meropenem- and tobramycin-treated Pseudomonas aeruginosa biofilms. J Antimicrob Chemother. 2017 Dec 01; 72(12):3357-3365. Haagensen J, Verotta D, Huang L, Engel J, Spormann AM, Yang K. PMID: 28961810; PMCID: PMC5890705.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    27. Impact of Intermittent Preventive Treatment During Pregnancy on Plasmodium falciparum Drug Resistance-Mediating Polymorphisms in Uganda. J Infect Dis. 2017 11 15; 216(8):1008-1017. Conrad MD, Mota D, Foster M, Tukwasibwe S, Legac J, Tumwebaze P, Whalen M, Kakuru A, Nayebare P, Wallender E, Havlir DV, Jagannathan P, Huang L, Aweeka F, Kamya MR, Dorsey G, Rosenthal PJ. PMID: 28968782; PMCID: PMC5853776.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    28. Concomitant nevirapine impacts pharmacokinetic exposure to the antimalarial artemether-lumefantrine in African children. PLoS One. 2017; 12(10):e0186589. Huang L, Carey V, Lindsey JC, Marzan F, Gingrich D, Graham B, Barlow-Mosha L, Ssemambo PK, Kamthunzi P, Nachman S, Parikh S, Aweeka FT, IMPAACT P1079 protocol team. PMID: 29065172; PMCID: PMC5655345.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    29. Pharmacokinetics and Model-Based Dosing to Optimize Fludarabine Therapy in Pediatric Hematopoietic Cell Transplant Recipients. Biol Blood Marrow Transplant. 2017 Oct; 23(10):1701-1713. Ivaturi V, Dvorak CC, Chan D, Liu T, Cowan MJ, Wahlstrom J, Stricherz M, Jennissen C, Orchard PJ, Tolar J, Pai SY, Huang L, Aweeka F, Long-Boyle J. PMID: 28684371; PMCID: PMC6108324.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCTClinical Trials
    30. Parasite Clearance and Artemether Pharmacokinetics Parameters Over the Course of Artemether-Lumefantrine Treatment for Malaria in Human Immunodeficiency Virus (HIV)-Infected and HIV-Uninfected Ugandan Children. Open Forum Infect Dis. 2016 Oct; 3(4):ofw217. Kajubi R, Huang L, Were M, Kiconco S, Li F, Marzan F, Gingrich D, Nyunt MM, Ssebuliba J, Mwebaza N, Aweeka FT, Parikh S. PMID: 28018925; PMCID: PMC5170492.
      View in: PubMed   Mentions: 3  
    31. Antiretroviral Choice for HIV Impacts Antimalarial Exposure and Treatment Outcomes in Ugandan Children. Clin Infect Dis. 2016 08 01; 63(3):414-22. Parikh S, Kajubi R, Huang L, Ssebuliba J, Kiconco S, Gao Q, Li F, Were M, Kakuru A, Achan J, Mwebaza N, Aweeka FT. PMID: 27143666; PMCID: PMC4946019.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    32. Artemether-Lumefantrine Pharmacokinetics and Clinical Response Are Minimally Altered in Pregnant Ugandan Women Treated for Uncomplicated Falciparum Malaria. Antimicrob Agents Chemother. 2015 Dec 14; 60(3):1274-82. Nyunt MM, Nguyen VK, Kajubi R, Huang L, Ssebuliba J, Kiconco S, Mwima MW, Achan J, Aweeka F, Parikh S, Mwebaza N. PMID: 26666942; PMCID: PMC4775973.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    33. Variable piperaquine exposure significantly impacts protective efficacy of monthly dihydroartemisinin-piperaquine for the prevention of malaria in Ugandan children. Malar J. 2015 Sep 24; 14:368. Sundell K, Jagannathan P, Huang L, Bigira V, Kapisi J, Kakuru MM, Savic R, Kamya MR, Dorsey G, Aweeka F. PMID: 26403465; PMCID: PMC4582734.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansPHPublic Health
    34. Artemether-Lumefantrine Exposure in HIV-Infected Nigerian Subjects on Nevirapine-Containing Antiretroviral Therapy. Antimicrob Agents Chemother. 2015 Dec; 59(12):7852-6. Parikh S, Fehintola F, Huang L, Olson A, Adedeji WA, Darin KM, Morse GD, Murphy RL, Taiwo BO, Akinyinka OO, Adewole IF, Aweeka FT, Scarsi KK. PMID: 26392500; PMCID: PMC4649208.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    35. Artemether-lumefantrine treatment of uncomplicated Plasmodium falciparum malaria: a systematic review and meta-analysis of day 7 lumefantrine concentrations and therapeutic response using individual patient data. BMC Med. 2015 Sep 18; 13:227. WorldWide Antimalarial Resistance Network (WWARN) Lumefantrine PK/PD Study Group. PMID: 26381375; PMCID: PMC4574542.
      View in: PubMed   Mentions: 55     Fields:    Translation:Humans
    36. New in vitro model to study the effect of human simulated antibiotic concentrations on bacterial biofilms. Antimicrob Agents Chemother. 2015 Jul; 59(7):4074-81. Haagensen JA, Verotta D, Huang L, Spormann A, Yang K. PMID: 25918138; PMCID: PMC4468651.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    37. Efficacy and safety of three regimens for the prevention of malaria in young HIV-exposed Ugandan children: a randomized controlled trial. AIDS. 2014 Nov 28; 28(18):2701-9. Kamya MR, Kapisi J, Bigira V, Clark TD, Kinara S, Mwangwa F, Muhindo MK, Kakuru A, Aweeka FT, Huang L, Jagannathan P, Achan J, Havlir DV, Rosenthal PJ, Dorsey G. PMID: 25493596; PMCID: PMC4487368.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    38. Alteration in cytochrome P450 3A4 activity as measured by a urine cortisol assay in HIV-1-infected pregnant women and relationship to antiretroviral pharmacokinetics. HIV Med. 2015 Mar; 16(3):176-83. Aweeka FT, Hu C, Huang L, Best BM, Stek A, Lizak P, Burchett SK, Read JS, Watts H, Mirochnick M, Capparelli EV, International Maternal Pediatric Adolescent AIDS Clinical Trials Group (IMPAACT) P1026s Protocol Tea. PMID: 25407158; PMCID: PMC4320673.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    39. Protective efficacy and safety of three antimalarial regimens for the prevention of malaria in young Ugandan children: a randomized controlled trial. PLoS Med. 2014 Aug; 11(8):e1001689. Bigira V, Kapisi J, Clark TD, Kinara S, Mwangwa F, Muhindo MK, Osterbauer B, Aweeka FT, Huang L, Achan J, Havlir DV, Rosenthal PJ, Kamya MR, Dorsey G. PMID: 25093754; PMCID: PMC4122345.
      View in: PubMed   Mentions: 71     Fields:    Translation:Humans
    40. Determination of meropenem in bacterial media by LC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Jun 15; 961:71-6. Huang L, Haagensen J, Verotta D, Lizak P, Aweeka F, Yang K. PMID: 24861874; PMCID: PMC4104812.
      View in: PubMed   Mentions: 7     Fields:    
    41. Simultaneous determination of fludarabine and clofarabine in human plasma by LC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Jun 01; 960:194-9. Huang L, Lizak P, Dvorak CC, Aweeka F, Long-Boyle J. PMID: 24820973; PMCID: PMC4110960.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    42. Plasma and Intracellular Population Pharmacokinetic Analysis of Fludarabine in Pediatric Allogeneic Hematopoietic Cell Transplant (alloHCT) Recipients. Biology of Blood and Marrow Transplantation. 2014 Feb 1; 20(2):s30. Long-Boyle LJ, Sambol SN, Dvorak DC, Cowan CM, Lee LS, Huang HL, Horn HB, Stricherz SM, Tolar TJ, Orchard OP, Jacobson JP, Aweeka AF. .
      View in: Publisher Site   Mentions:
    43. Determination of the antimalarial drug piperaquine in small volume pediatric plasma samples by LC-MS/MS. Bioanalysis. 2014; 6(23):3081-9. Kjellin LL, Dorsey G, Rosenthal PJ, Aweeka F, Huang L. PMID: 25529877; PMCID: PMC4321809.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    44. Determination of intracellular fludarabine triphosphate in human peripheral blood mononuclear cells by LC-MS/MS. J Pharm Biomed Anal. 2013 Dec; 86:198-203. Huang L, Lizak P, Aweeka F, Long-Boyle J. PMID: 24013121; PMCID: PMC3835489.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    45. Determination of artemether and dihydroartemisinin in human plasma with a new hydrogen peroxide stabilization method. Bioanalysis. 2013 Jun; 5(12):1501-6. Huang L, Olson A, Gingrich D, Aweeka FT. PMID: 23795928; PMCID: PMC3879143.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    46. Nevirapine inhibits the anti-HIV activity of CD8+ cells. J Acquir Immune Defic Syndr. 2013 Jun 01; 63(2):184-8. Liu L, Wang L, Huang L, Siu V, Teque F, Aweeka FT, Levy JA. PMID: 23392464; PMCID: PMC3653990.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    47. Co-administration of a commonly used Zimbabwean herbal treatment (African potato) does not alter the pharmacokinetics of lopinavir/ritonavir. Int J Infect Dis. 2013 Oct; 17(10):e857-61. Gwaza L, Aweeka F, Greenblatt R, Lizak P, Huang L, Guglielmo BJ. PMID: 23587599; PMCID: PMC3776002.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCTClinical Trials
    48. Concomitant efavirenz reduces pharmacokinetic exposure to the antimalarial drug artemether-lumefantrine in healthy volunteers. J Acquir Immune Defic Syndr. 2012 Nov 01; 61(3):310-6. Huang L, Parikh S, Rosenthal PJ, Lizak P, Marzan F, Dorsey G, Havlir D, Aweeka FT. PMID: 22918158; PMCID: PMC3511816.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    49. In vitro metabolism of piperaquine is primarily mediated by CYP3A4. Xenobiotica. 2012 Nov; 42(11):1088-95. Lee TM, Huang L, Johnson MK, Lizak P, Kroetz D, Aweeka F, Parikh S. PMID: 22671777; PMCID: PMC5087332.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    50. Determination of lumefantrine in small-volume human plasma by LC-MS/MS: using a deuterated lumefantrine to overcome matrix effect and ionization saturation. Bioanalysis. 2012 Jan; 4(2):157-66. Huang L, Li X, Marzan F, Lizak PS, Aweeka FT. PMID: 22250798; PMCID: PMC3321395.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    51. An Interim Evaluation of Systemic F-Ara-a Exposure in Pediatric Allogeneic Hematopoietic Cell Transplant (alloHCT) Recipients Using An Optimal Sampling Design. Blood. 2011 Nov 18; 118(21):1962-1962. Long-Boyle LJ, Yan YS, Dvorak DC, Horn HB, Cowan CM, Huang HL, Sambol SN, Musick ML, Aweeka AF. .
      View in: Publisher Site   Mentions:
    52. A modified method for determination of lumefantrine in human plasma by HPLC-UV and combination of protein precipitation and solid-phase extraction: application to a pharmacokinetic study. Anal Chem Insights. 2010 Mar 29; 5:15-23. Huang L, Lizak PS, Jayewardene AL, Marzan F, Lee MN, Aweeka FT. PMID: 20448843; PMCID: PMC2865164.
      View in: PubMed   Mentions: 7  
    53. Development and validation of a high-performance liquid chromatography/tandem mass spectrometry method for the determination of artemether and its active metabolite dihydroartemisinin in human plasma. J Pharm Biomed Anal. 2009 Dec 05; 50(5):959-65. Huang L, Jayewardene AL, Li X, Marzan F, Lizak PS, Aweeka FT. PMID: 19646837; PMCID: PMC3034030.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    54. Development and validation of a hydrophilic interaction liquid chromatography-tandem mass spectrometry method for determination of isoniazid in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Jan 15; 877(3):285-90. Huang L, Marzan F, Jayewardene AL, Lizak PS, Li X, Aweeka FT. PMID: 19112051; PMCID: PMC3032609.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    55. Arthromyces ramosus peroxidase produces two chlorinating species. Biochem Biophys Res Commun. 2007 Apr 06; 355(2):581-6. Huang L, Ortiz de Montellano PR. PMID: 17303078; PMCID: PMC1852486.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    56. Different protein-binding selectivities for N-acyl heparin derivatives having N-phenylacetyl and heterocycle analogs of N-phenylacetyl substituted in place of N-sulfo groups. Bioorg Med Chem Lett. 2007 Jan 15; 17(2):419-23. Huang L, Fernández C, Kerns RJ. PMID: 17070049.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    57. Role of heme-protein covalent bonds in mammalian peroxidases. Protection of the heme by a single engineered heme-protein link in horseradish peroxidase. J Biol Chem. 2006 Jul 14; 281(28):18983-8. Huang L, Wojciechowski G, Ortiz de Montellano PR. PMID: 16651262.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    58. Heme-protein covalent bonds in peroxidases and resistance to heme modification during halide oxidation. Arch Biochem Biophys. 2006 Feb 01; 446(1):77-83. Huang L, Ortiz de Montellano PR. PMID: 16375846.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    59. Diversity-oriented chemical modification of heparin: Identification of charge-reduced N-acyl heparin derivatives having increased selectivity for heparin-binding proteins. Bioorg Med Chem. 2006 Apr 01; 14(7):2300-13. Huang L, Kerns RJ. PMID: 16314105.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    60. Autocatalytic modification of the prosthetic heme of horseradish but not lactoperoxidase by thiocyanate oxidation products. A role for heme-protein covalent cross-linking. J Am Chem Soc. 2005 Nov 16; 127(45):15871-9. Wojciechowski G, Huang L, Ortiz de Montellano PR. PMID: 16277530.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    61. Prosthetic heme modification during halide ion oxidation. Demonstration of chloride oxidation by horseradish peroxidase. J Am Chem Soc. 2005 Apr 20; 127(15):5345-53. Huang L, Wojciechowski G, Ortiz de Montellano PR. PMID: 15826172.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    62. Oxidation of carboxylic acids by horseradish peroxidase results in prosthetic heme modification and inactivation. J Am Chem Soc. 2004 Oct 13; 126(40):12865-73. Huang L, Colas C, Ortiz de Montellano PR. PMID: 15469283.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    63. Human heme oxygenase oxidation of 5- and 15-phenylhemes. J Biol Chem. 2004 Oct 08; 279(41):42593-604. Wang J, Niemevz F, Lad L, Huang L, Alvarez DE, Buldain G, Poulos TL, de Montellano PR. PMID: 15297453.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    64. Computer-aided molecular design of HIV-1 protease dissociative inhibitors. Acta Pharmaceutica Sinica (YaoXueXueBao). 1999; (5):353-357. Huang L, Tao G, Li L, Chi H.
    65. Method for determination of total mercury in foods by atomic fluorescence spectrometry. J. Chinese Food Hygiene. 1997; (1):3-5. Huang L, Yang H.
    66. Study on the tolerance limit for nitrite in Chinese foods. Hygiene Research. 1995; 24:176-178. Yang H, Huang L, Xie B.
    67. Monitoring of lead content in foodstuff in China. J. Chinese Preventive Medicine. 1995; 29:96-98. Yang H, Zou Z, Jin C, Yi F, Liang C, Xu X, Wang X, Huang, L.
    68. A study on cadmium content in foods of six provinces and cities. J. Chinese Prenentive Medicine. 1994; 28:6-8. Yang H, Zou Z, Jin C, Gu W, Liang C, Yi F, Xie B, Huang, L.
    69. Survey of mercury contamination of food in some areas of China. J. Hygiene Research. 1994; 23:95-96. Yang H, Han Y, Huang L.
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