Binh Diep, PhD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address1001 Potrero Avenue, #3408
San Francisco CA 94110
Phone408-410-3897
Emailbinh.diep@ucsf.edu
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPostdoc2008Microbial Pathogenesis
    University of California, BerkeleyPhD2005Infectious Diseases and Immunity
    University of California, BerkeleyB.A.2000Molecular Cell Biology
    Collapse Awards and Honors
    American Society for Microbiology2010ICAAC Young Investigator Award
    Pfizer2009ASPIRE Young Investigator Award

    Collapse Research 
    Collapse Research Activities and Funding
    Rabbit models of P. aeruginosa acute pneumonia, severe sepsis, and ventilator-associated pneumonia for novel antibacterial development
    Food and Drug Administration HHSF223201710112CSep 15, 2017 - Sep 14, 2020
    Role: Principal Investigator
    Novel Mechanisms of Beta-lactam Resistance in Staph Aureus
    NIH R56AI100291Aug 1, 2012 - Dec 31, 2017
    Role: Co-Principal Investigator
    Mechanisms of PVL-induced Acute Lung Injury
    NIH R01AI087674Jun 15, 2010 - May 31, 2016
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Development and validation of a rabbit model of Pseudomonas aeruginosa non-ventilated pneumonia for preclinical drug development. Front Cell Infect Microbiol. 2023; 13:1297281. Gras E, Vu TTT, Nguyen NTQ, Tran VG, Mao Y, Tran ND, Mai NH, Dong OX, Jung DH, Iorio NLPP, Povoa HCC, Pinheiro MG, Aguiar-Alves F, Weiss WJ, Zheng B, Cheng LI, Stover CK, Sellman BR, DiGiandomenico A, Gibault L, Valour F, Diep BA. PMID: 38149013; PMCID: PMC10750358.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    2. Monoclonal antibodies neutralizing alpha-hemolysin, bicomponent leukocidins, and clumping factor A protected against Staphylococcus aureus-induced acute circulatory failure in a mechanically ventilated rabbit model of hyperdynamic septic shock. Front Immunol. 2023; 14:1260627. Nguyen NTQ, Doan TNM, Sato K, Tkaczyk C, Sellman BR, Diep BA. PMID: 37781371; PMCID: PMC10541218.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Antivirulence Bispecific Monoclonal Antibody-Mediated Protection against Pseudomonas aeruginosa Ventilator-Associated Pneumonia in a Rabbit Model. Antimicrob Agents Chemother. 2022 02 15; 66(2):e0202221. Aguiar-Alves F, Le HN, Tran VG, Gras E, Vu TTT, Dong OX, Quetz JS, Cheng LI, Yu L, Sellman BR, Stover CK, DiGiandomenico A, Diep BA. PMID: 34902264; PMCID: PMC8846318.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    4. Pseudomonas aeruginosa Ventilator-Associated Pneumonia Rabbit Model for Preclinical Drug Development. Antimicrob Agents Chemother. 2021 06 17; 65(7):e0272420. Nguyen NTQ, Gras E, Tran ND, Nguyen NNY, Lam HTH, Weiss WJ, Doan TNM, Diep BA. PMID: 33972247; PMCID: PMC8218622.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    5. Multimechanistic Monoclonal Antibody Combination Targeting Key Staphylococcus aureus Virulence Determinants in a Rabbit Model of Prosthetic Joint Infection. Antimicrob Agents Chemother. 2021 06 17; 65(7):e0183220. Mao Y, Valour F, Nguyen NTQ, Doan TMN, Koelkebeck H, Richardson C, Cheng LI, Sellman BR, Tkaczyk C, Diep BA. PMID: 33903108; PMCID: PMC8218614.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    6. IBT-V02: A Multicomponent Toxoid Vaccine Protects Against Primary and Secondary Skin Infections Caused by Staphylococcus aureus. Front Immunol. 2021; 12:624310. Karauzum H, Venkatasubramaniam A, Adhikari RP, Kort T, Holtsberg FW, Mukherjee I, Mednikov M, Ortines R, Nguyen NTQ, Doan TMN, Diep BA, Lee JC, Aman MJ. PMID: 33777005; PMCID: PMC7987673.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCellsPHPublic Health
    7. Staphylococcus aureus Interferes with Streptococci Spatial Distribution and with Protein Expression of Species within a Polymicrobial Oral Biofilm. Antibiotics (Basel). 2021 Jan 26; 10(2). Schnurr E, Paqué PN, Attin T, Nanni P, Grossmann J, Holtfreter S, Bröker BM, Kohler C, Diep BA, Ribeiro AA, Thurnheer T. PMID: 33530340; PMCID: PMC7911025.
      View in: PubMed   Mentions: 4  
    8. FDA Public Workshop Summary: Advancing Animal Models for Antibacterial Drug Development. Antimicrob Agents Chemother. 2020 12 16; 65(1). Byrne JM, Waack U, Weinstein EA, Joshi A, Shurland SM, Iarikov D, Bulitta JB, Diep BA, Guina T, Hope WW, Lawrenz MB, Lepak AJ, Luna BM, Miesel L, Phipps AJ, Walsh TJ, Weiss W, Amini T, Farley JJ. PMID: 33106262; PMCID: PMC7927847.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    9. Protective Efficacy of Monoclonal Antibodies Neutralizing Alpha-Hemolysin and Bicomponent Leukocidins in a Rabbit Model of Staphylococcus aureus Necrotizing Pneumonia. Antimicrob Agents Chemother. 2020 02 21; 64(3). Vu TTT, Nguyen NTQ, Tran VG, Gras E, Mao Y, Jung DH, Tkaczyk C, Sellman BR, Diep BA. PMID: 31844012; PMCID: PMC7038280.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    10. Efficacy of Active Immunization With Attenuated α-Hemolysin and Panton-Valentine Leukocidin in a Rabbit Model of Staphylococcus aureus Necrotizing Pneumonia. J Infect Dis. 2020 01 02; 221(2):267-275. Tran VG, Venkatasubramaniam A, Adhikari RP, Krishnan S, Wang X, Le VTM, Le HN, Vu TTT, Schneider-Smith E, Aman MJ, Diep BA. PMID: 31504652; PMCID: PMC6936001.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    11. Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria. Cell Host Microbe. 2019 12 11; 26(6):795-809.e5. Leech JM, Dhariwala MO, Lowe MM, Chu K, Merana GR, Cornuot C, Weckel A, Ma JM, Leitner EG, Gonzalez JR, Vasquez KS, Diep BA, Scharschmidt TC. PMID: 31784259; PMCID: PMC6989301.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    12. 713. Preventive Administration of MEDI6389, a Combination of Monoclonal Antibodies (mAbs) Targeting Alpha-Toxin (AT), Panton-Valentine Leukocidin (PVL), Leukocidin ED (LukED), Gamma-Hemolysin and Clumping Factor A (ClfA), in a Rabbit Model of USA300 MRSA Prosthetic Joint Infection (PJI). Open Forum Infectious Diseases. 2019 Oct 23; 6(Suppl 2):s320-s321. Yanjie YM, Valour VF, Tran TG, Vu VT, Delaye DT, Nguyen NT, Tkaczyk TC, Cheng CL, Sellman SB, Diep DB. .
      View in: Publisher Site   Mentions:
    13. Treatment Efficacy of MEDI3902 in Pseudomonas aeruginosa Bloodstream Infection and Acute Pneumonia Rabbit Models. Antimicrob Agents Chemother. 2019 08; 63(8). Le HN, Tran VG, Vu TTT, Gras E, Le VTM, Pinheiro MG, Aguiar-Alves F, Schneider-Smith E, Carter HC, Sellman BR, Stover CK, DiGiandomenico A, Diep BA. PMID: 31160288; PMCID: PMC6658784.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    14. Necrotizing Soft Tissue Infection Staphylococcus aureus but not S. pyogenes Isolates Display High Rates of Internalization and Cytotoxicity Toward Human Myoblasts. J Infect Dis. 2019 07 19; 220(4):710-719. Baude J, Bastien S, Gillet Y, Leblanc P, Itzek A, Tristan A, Bes M, Duguez S, Moreau K, Diep BA, Norrby-Teglund A, Henry T, Vandenesch F, INFECT Study Group. PMID: 31001627.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    15. 925 Neonatal priming shapes preferential capacity for immune tolerance to skin commensal vs. pathogenic bacteria. Journal of Investigative Dermatology. 2018 May 1; 138(5):s157. Leech LJ, Chu CK, Leitner LE, Moon MJ, Diep DB, Scharschmidt ST. .
      View in: Publisher Site   Mentions:
    16. MEDI3902 Correlates of Protection against Severe Pseudomonas aeruginosa Pneumonia in a Rabbit Acute Pneumonia Model. Antimicrob Agents Chemother. 2018 05; 62(5). Le HN, Quetz JS, Tran VG, Le VTM, Aguiar-Alves F, Pinheiro MG, Cheng L, Yu L, Sellman BR, Stover CK, DiGiandomenico A, Diep BA. PMID: 29483116; PMCID: PMC5923159.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    17. Demographic fluctuation of community-acquired antibiotic-resistant Staphylococcus aureus lineages: potential role of flimsy antibiotic exposure. ISME J. 2018 08; 12(8):1879-1894. Gustave CA, Tristan A, Martins-Simões P, Stegger M, Benito Y, Andersen PS, Bes M, Le Hir T, Diep BA, Uhlemann AC, Glaser P, Laurent F, Wirth T, Vandenesch F. PMID: 29599521; PMCID: PMC6052156.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    18. The Role of Antibiotics in Modulating Virulence in Staphylococcus aureus. Clin Microbiol Rev. 2017 10; 30(4):887-917. Hodille E, Rose W, Diep BA, Goutelle S, Lina G, Dumitrescu O. PMID: 28724662; PMCID: PMC5608880.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    19. Effects of Tedizolid Phosphate on Survival Outcomes and Suppression of Production of Staphylococcal Toxins in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia. Antimicrob Agents Chemother. 2017 04; 61(4). Le VT, Le HN, Pinheiro MG, Hahn KJ, Dinh ML, Larson KB, Flanagan SD, Badiou C, Lina G, Tkaczyk C, Sellman BR, Diep BA. PMID: 28137816; PMCID: PMC5365717.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    20. Targeting Alpha Toxin To Mitigate Its Lethal Toxicity in Ferret and Rabbit Models of Staphylococcus aureus Necrotizing Pneumonia. Antimicrob Agents Chemother. 2017 04; 61(4). Diep BA, Hilliard JJ, Le VT, Tkaczyk C, Le HN, Tran VG, Rao RL, Dip EC, Pereira-Franchi EP, Cha P, Jacobson S, Broome R, Cheng LI, Weiss W, Prokai L, Nguyen V, Stover CK, Sellman BR. PMID: 28115346; PMCID: PMC5365647.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    21. Delta Hemolysin and Phenol-Soluble Modulins, but Not Alpha Hemolysin or Panton-Valentine Leukocidin, Induce Mast Cell Activation. Front Cell Infect Microbiol. 2016; 6:180. Hodille E, Cuerq C, Badiou C, Bienvenu F, Steghens JP, Cartier R, Bes M, Tristan A, Plesa A, Le VT, Diep BA, Lina G, Dumitrescu O. PMID: 28018862; PMCID: PMC5149515.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    22. Critical Role of Alpha-Toxin and Protective Effects of Its Neutralization by a Human Antibody in Acute Bacterial Skin and Skin Structure Infections. Antimicrob Agents Chemother. 2016 10; 60(10):5640-8. Le VT, Tkaczyk C, Chau S, Rao RL, Dip EC, Pereira-Franchi EP, Cheng L, Lee S, Koelkebeck H, Hilliard JJ, Yu XQ, Datta V, Nguyen V, Weiss W, Prokai L, O'Day T, Stover CK, Sellman BR, Diep BA. PMID: 27401576; PMCID: PMC5038308.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    23. Improved Protection in a Rabbit Model of Community-Associated Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia upon Neutralization of Leukocidins in Addition to Alpha-Hemolysin. Antimicrob Agents Chemother. 2016 10; 60(10):6333-40. Diep BA, Le VT, Visram ZC, Rouha H, Stulik L, Dip EC, Nagy G, Nagy E. PMID: 27527081; PMCID: PMC5038318.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    24. IVIG-mediated protection against necrotizing pneumonia caused by MRSA. Sci Transl Med. 2016 09 21; 8(357):357ra124. Diep BA, Le VT, Badiou C, Le HN, Pinheiro MG, Duong AH, Wang X, Dip EC, Aguiar-Alves F, Basuino L, Marbach H, Mai TT, Sarda MN, Kajikawa O, Matute-Bello G, Tkaczyk C, Rasigade JP, Sellman BR, Chambers HF, Lina G. PMID: 27655850.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    25. Staphylococcus aureus α toxin potentiates opportunistic bacterial lung infections. Sci Transl Med. 2016 Mar 09; 8(329):329ra31. Cohen TS, Hilliard JJ, Jones-Nelson O, Keller AE, O'Day T, Tkaczyk C, DiGiandomenico A, Hamilton M, Pelletier M, Wang Q, Diep BA, Le VT, Cheng L, Suzich J, Stover CK, Sellman BR. PMID: 26962155.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    26. Functional characteristics of the Staphylococcus aureus δ-toxin allelic variant G10S. Sci Rep. 2015 Dec 10; 5:18023. Cheung GY, Yeh AJ, Kretschmer D, Duong AC, Tuffuor K, Fu CL, Joo HS, Diep BA, Li M, Nakamura Y, Nunez G, Peschel A, Otto M. PMID: 26658455; PMCID: PMC4674873.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    27. Ceftobiprole- and ceftaroline-resistant methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2015 May; 59(5):2960-3. Chan LC, Basuino L, Diep B, Hamilton S, Chatterjee SS, Chambers HF. PMID: 25753637; PMCID: PMC4394828.
      View in: PubMed   Mentions: 38     Fields:    Translation:Cells
    28. Differential expression and roles of Staphylococcus aureus virulence determinants during colonization and disease. mBio. 2015 Feb 17; 6(1):e02272-14. Jenkins A, Diep BA, Mai TT, Vo NH, Warrener P, Suzich J, Stover CK, Sellman BR. PMID: 25691592; PMCID: PMC4337569.
      View in: PubMed   Mentions: 94     Fields:    Translation:AnimalsCells
    29. Global gene expression of methicillin-resistant Staphylococcus aureus USA300 during human and mouse infection. J Infect Dis. 2014 May 15; 209(10):1542-50. Date SV, Modrusan Z, Lawrence M, Morisaki JH, Toy K, Shah IM, Kim J, Park S, Xu M, Basuino L, Chan L, Zeitschel D, Chambers HF, Tan MW, Brown EJ, Diep BA, Hazenbos WL. PMID: 24286981.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    30. Identifying potential therapeutic targets of methicillin-resistant Staphylococcus aureus through in vivo proteomic analysis. J Infect Dis. 2014 May 15; 209(10):1533-41. Diep BA, Phung Q, Date S, Arnott D, Bakalarski C, Xu M, Nakamura G, Swem DL, Alexander MK, Le HN, Mai TT, Tan MW, Brown EJ, Nishiyama M. PMID: 24280367; PMCID: PMC3997574.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    31. Novel staphylococcal glycosyltransferases SdgA and SdgB mediate immunogenicity and protection of virulence-associated cell wall proteins. PLoS Pathog. 2013; 9(10):e1003653. Hazenbos WL, Kajihara KK, Vandlen R, Morisaki JH, Lehar SM, Kwakkenbos MJ, Beaumont T, Bakker AQ, Phung Q, Swem LR, Ramakrishnan S, Kim J, Xu M, Shah IM, Diep BA, Sai T, Sebrell A, Khalfin Y, Oh A, Koth C, Lin SJ, Lee BC, Strandh M, Koefoed K, Andersen PS, Spits H, Brown EJ, Tan MW, Mariathasan S. PMID: 24130480; PMCID: PMC3794999.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    32. Selected insights from application of whole-genome sequencing for outbreak investigations. Curr Opin Crit Care. 2013 Oct; 19(5):432-9. Le VT, Diep BA. PMID: 23856896; PMCID: PMC4104273.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansPHPublic Health
    33. Panton-Valentine leucocidin and pneumonia. Lancet Infect Dis. 2013 Jul; 13(7):566. Diep BA, Gillet Y, Etienne J, Lina G, Vandenesch F. PMID: 23809217.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    34. PSMs of hypervirulent Staphylococcus aureus act as intracellular toxins that kill infected osteoblasts. PLoS One. 2013; 8(5):e63176. Rasigade JP, Trouillet-Assant S, Ferry T, Diep BA, Sapin A, Lhoste Y, Ranfaing J, Badiou C, Benito Y, Bes M, Couzon F, Tigaud S, Lina G, Etienne J, Vandenesch F, Laurent F. PMID: 23690994; PMCID: PMC3653922.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    35. Effects of linezolid on suppressing in vivo production of staphylococcal toxins and improving survival outcomes in a rabbit model of methicillin-resistant Staphylococcus aureus necrotizing pneumonia. J Infect Dis. 2013 Jul; 208(1):75-82. Diep BA, Afasizheva A, Le HN, Kajikawa O, Matute-Bello G, Tkaczyk C, Sellman B, Badiou C, Lina G, Chambers HF. PMID: 23532096; PMCID: PMC3666136.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    36. Use of whole-genome sequencing for outbreak investigations. Lancet Infect Dis. 2013 Feb; 13(2):99-101. Diep BA. PMID: 23158673.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCellsPHPublic Health
    37. Clonal composition and community clustering of drug-susceptible and -resistant Escherichia coli isolates from bloodstream infections. Antimicrob Agents Chemother. 2013 Jan; 57(1):490-7. Adams-Sapper S, Diep BA, Perdreau-Remington F, Riley LW. PMID: 23147723; PMCID: PMC3535975.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    38. Concurrent epidemics of skin and soft tissue infection and bloodstream infection due to community-associated methicillin-resistant Staphylococcus aureus. Clin Infect Dis. 2012 Sep; 55(6):781-8. Tattevin P, Schwartz BS, Graber CJ, Volinski J, Bhukhen A, Bhukhen A, Mai TT, Vo NH, Dang DN, Phan TH, Basuino L, Perdreau-Remington F, Chambers HF, Diep BA. PMID: 22670044; PMCID: PMC3657511.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCellsPHPublic Health
    39. Linezolid effects on bacterial toxin production and host immune response: review of the evidence. Curr Ther Res Clin Exp. 2012 Jun; 73(3):86-102. Diep BA, Equils O, Huang DB, Gladue R. PMID: 24648596; PMCID: PMC3954010.
      View in: PubMed   Mentions: 10     Fields:    
    40. MRSA epidemic linked to a quickly spreading colonization and virulence determinant. Nat Med. 2012 May; 18(5):816-9. Li M, Du X, Villaruz AE, Diep BA, Wang D, Song Y, Tian Y, Hu J, Yu F, Lu Y, Otto M. PMID: 22522561; PMCID: PMC3378817.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansAnimalsCells
    41. Globally dispersed mobile drug-resistance genes in gram-negative bacterial isolates from patients with bloodstream infections in a US urban general hospital. J Med Microbiol. 2012 Jul; 61(Pt 7):968-974. Adams-Sapper S, Sergeevna-Selezneva J, Tartof S, Raphael E, Diep BA, Perdreau-Remington F, Riley LW. PMID: 22493279; PMCID: PMC3542709.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    42. Cross-talk between Staphylococcus aureus leukocidins-intoxicated macrophages and lung epithelial cells triggers chemokine secretion in an inflammasome-dependent manner. Cell Microbiol. 2012 Jul; 14(7):1019-36. Perret M, Badiou C, Lina G, Burbaud S, Benito Y, Bes M, Cottin V, Couzon F, Juruj C, Dauwalder O, Goutagny N, Diep BA, Vandenesch F, Henry T. PMID: 22329718.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    43. Global changes in Staphylococcus aureus gene expression in human blood. PLoS One. 2011 Apr 15; 6(4):e18617. Malachowa N, Whitney AR, Kobayashi SD, Sturdevant DE, Kennedy AD, Braughton KR, Shabb DW, Diep BA, Chambers HF, Otto M, DeLeo FR. PMID: 21525981; PMCID: PMC3078114.
      View in: PubMed   Mentions: 134     Fields:    Translation:HumansAnimalsCells
    44. Widespread Skin and Soft-Tissue Infections Due to Two Methicillin-Resistant Staphylococcus aureus Strains Harboring the Genes for Panton-Valentine Leucocidin. Journal of Clinical Microbiology. 2010 Sep 1; 48(9):3461-3461. Diep DB, Sensabaugh SG, Somboonna SN, Carleton CH, Perdreau-Remington PF. .
      View in: Publisher Site   Mentions:
    45. Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury. Proc Natl Acad Sci U S A. 2010 Mar 23; 107(12):5587-92. Diep BA, Chan L, Tattevin P, Kajikawa O, Martin TR, Basuino L, Mai TT, Marbach H, Braughton KR, Whitney AR, Gardner DJ, Fan X, Tseng CW, Liu GY, Badiou C, Etienne J, Lina G, Matthay MA, DeLeo FR, Chambers HF. PMID: 20231457; PMCID: PMC2851770.
      View in: PubMed   Mentions: 185     Fields:    Translation:HumansAnimalsCells
    46. Relative contribution of Panton-Valentine leukocidin to PMN plasma membrane permeability and lysis caused by USA300 and USA400 culture supernatants. Microbes Infect. 2010 Jun; 12(6):446-56. Graves SF, Kobayashi SD, Braughton KR, Diep BA, Chambers HF, Otto M, Deleo FR. PMID: 20172045; PMCID: PMC2883622.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    47. Characterization of baseline methicillin-resistant Staphylococcus aureus isolates recovered from phase IV clinical trial for linezolid. J Clin Microbiol. 2010 Feb; 48(2):568-74. Mendes RE, Sader HS, Deshpande LM, Diep BA, Chambers HF, Jones RN. PMID: 19940054; PMCID: PMC2815625.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCellsCTClinical Trials
    48. Ceftobiprole is superior to vancomycin, daptomycin, and linezolid for treatment of experimental endocarditis in rabbits caused by methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2010 Feb; 54(2):610-3. Tattevin P, Basuino L, Bauer D, Diep BA, Chambers HF. PMID: 19917746; PMCID: PMC2812130.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    49. Genetic diversity of arginine catabolic mobile element in Staphylococcus epidermidis. PLoS One. 2009 Nov 06; 4(11):e7722. Miragaia M, de Lencastre H, Perdreau-Remington F, Chambers HF, Higashi J, Sullam PM, Lin J, Wong KI, King KA, Otto M, Sensabaugh GF, Diep BA. PMID: 19893740; PMCID: PMC2768820.
      View in: PubMed   Mentions: 50     Fields:    Translation:Cells
    50. Staphylococcus aureus Panton-Valentine leukocidin contributes to inflammation and muscle tissue injury. PLoS One. 2009 Jul 27; 4(7):e6387. Tseng CW, Kyme P, Low J, Rocha MA, Alsabeh R, Miller LG, Otto M, Arditi M, Diep BA, Nizet V, Doherty TM, Beenhouwer DO, Liu GY. PMID: 19633710; PMCID: PMC2711303.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    51. Methicillin-resistant Staphylococcus aureus USA300 clone in long-term care facility. Emerg Infect Dis. 2009 Jun; 15(6):953-5. Tattevin P, Diep BA, Jula M, Perdreau-Remington F. PMID: 19523301; PMCID: PMC2727319.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    52. Doxycycline, not minocycline, induces its own resistance in multidrug-resistant, community-associated methicillin-resistant Staphylococcus aureus clone USA300. Clin Infect Dis. 2009 May 15; 48(10):1483-4. Schwartz BS, Graber CJ, Diep BA, Basuino L, Perdreau-Remington F, Chambers HF. PMID: 19374563.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    53. Evolution of virulence in epidemic community-associated methicillin-resistant Staphylococcus aureus. Proc Natl Acad Sci U S A. 2009 Apr 07; 106(14):5883-8. Li M, Diep BA, Villaruz AE, Braughton KR, Jiang X, DeLeo FR, Chambers HF, Lu Y, Otto M. PMID: 19293374; PMCID: PMC2667066.
      View in: PubMed   Mentions: 220     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    54. Host defense and pathogenesis in Staphylococcus aureus infections. Infect Dis Clin North Am. 2009 Mar; 23(1):17-34. DeLeo FR, Diep BA, Otto M. PMID: 19135914; PMCID: PMC2748223.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansCells
    55. Relationship between susceptibility to daptomycin in vitro and activity in vivo in a rabbit model of aortic valve endocarditis. Antimicrob Agents Chemother. 2009 Apr; 53(4):1463-7. Chambers HF, Basuino L, Diep BA, Steenbergen J, Zhang S, Tattevin P, Alder J. PMID: 19171803; PMCID: PMC2663086.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
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    75. Increasing prevalence of methicillin-resistant Staphylococcus aureus infection in California jails. Clin Infect Dis. 2003 Nov 15; 37(10):1384-8. Pan ES, Diep BA, Carleton HA, Charlebois ED, Sensabaugh GF, Haller BL, Perdreau-Remington F. PMID: 14583874.
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