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Arp2/3 complex activity enables nuclear YAP for naïve pluripotency of human embryonic stem cells. Elife. 2024 Sep 25; 13.
Meyer NP, Singh T, Kutys ML, Nystul TG, Barber DL. PMID: 39319536.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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A role for pH dynamics regulating transcription factor DNA binding selectivity. bioRxiv. 2024 May 21.
Kisor KP, Ruiz DG, Jacobson MP, Barber DL. PMID: 38826444; PMCID: PMC11142074.
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TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments. Immunity. 2023 Dec 12; 56(12):2682-2698.e9.
Tsai YL, Arias-Badia M, Kadlecek TA, Lwin YM, Srinath A, Shah NH, Wang ZE, Barber D, Kuriyan J, Fong L, Weiss A. PMID: 38091950; PMCID: PMC10785950.
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PubMed Mentions:
3 Fields:
Translation:
Cells
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Intracellular pH dynamics regulates intestinal stem cell lineage specification. Nat Commun. 2023 06 23; 14(1):3745.
Liu Y, Reyes E, Castillo-Azofeifa D, Klein OD, Nystul T, Barber DL. PMID: 37353491; PMCID: PMC10290085.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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pH dynamics regulates transcription factor-DNA binding. Biophysical Journal. 2023 Feb 1; 122(3):214a-215a.
Kisor KK, Barber BD. .
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Arp2/3 complex activity is necessary for mouse ESC differentiation, times formative pluripotency, and enables lineage specification. Stem Cell Reports. 2022 06 14; 17(6):1318-1333.
Aloisio FM, Barber DL. PMID: 35658973; PMCID: PMC9214060.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Low pH Facilitates Heterodimerization of Mutant Isocitrate Dehydrogenase IDH1-R132H and Promotes Production of 2-Hydroxyglutarate. Biochemistry. 2021 06 29; 60(25):1983-1994.
Sesanto R, Kuehn JF, Barber DL, White KA. PMID: 34143606; PMCID: PMC8246651.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Ethyl isopropyl amiloride decreases oxidative phosphorylation and increases mitochondrial fusion in clonal untransformed and cancer cells. Am J Physiol Cell Physiol. 2021 07 01; 321(1):C147-C157.
Manoli SS, Kisor K, Webb BA, Barber DL. PMID: 34038242; PMCID: PMC8321791.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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pHLARE: a new biosensor reveals decreased lysosome pH in cancer cells. Mol Biol Cell. 2021 01 15; 32(2):131-142.
Webb BA, Aloisio FM, Charafeddine RA, Cook J, Wittmann T, Barber DL. PMID: 33237838; PMCID: PMC8120692.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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An acidic residue buried in the dimer interface of isocitrate dehydrogenase 1 (IDH1) helps regulate catalysis and pH sensitivity. Biochem J. 2020 08 28; 477(16):2999-3018.
Luna LA, Lesecq Z, White KA, Hoang A, Scott DA, Zagnitko O, Bobkov AA, Barber DL, Schiffer JM, Isom DG, Sohl CD. PMID: 32729927; PMCID: PMC7996970.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Intracellular pH Regulates Cancer and Stem Cell Behaviors: A Protein Dynamics Perspective. Front Oncol. 2020; 10:1401.
Liu Y, White KA, Barber DL. PMID: 32983969; PMCID: PMC7479815.
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PubMed Mentions:
19
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Editorial overview: Cell dynamics: Integrating cell dynamics across scales. Curr Opin Cell Biol. 2020 10; 66:130-132.
Barber DL, Trepat X. PMID: 32791470.
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PubMed Mentions: Fields:
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Filament assembly by the liver phosphofructokinase-1, the “gatekeeper” of glycolysis. The FASEB Journal. 2020 Apr 1; 34(S1):1-1.
Webb WB, Dosey DA, Wittmann WT, Kollmann KJ, Barber BD. .
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Intracellular pH dynamics and charge-changing somatic mutations in cancer. Cancer Metastasis Rev. 2019 06; 38(1-2):17-24.
White KA, Kisor K, Barber DL. PMID: 30982102.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Drosophila anion exchanger 2 is required for proper ovary development and oogenesis. Dev Biol. 2019 08 15; 452(2):127-133.
Benitez M, Tatapudy S, Liu Y, Barber DL, Nystul TG. PMID: 31071312; PMCID: PMC6592727.
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PubMed Mentions:
8 Fields:
Translation:
Animals
-
Tau repeat regions contain conserved histidine residues that modulate microtubule-binding in response to changes in pH. J Biol Chem. 2019 05 31; 294(22):8779-8790.
Charafeddine RA, Cortopassi WA, Lak P, Tan R, McKenney RJ, Jacobson MP, Barber DL, Wittmann T. PMID: 30992364; PMCID: PMC6552421.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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β-Catenin is a pH sensor with decreased stability at higher intracellular pH. J Cell Biol. 2018 11 05; 217(11):3965-3976.
White KA, Grillo-Hill BK, Esquivel M, Peralta J, Bui VN, Chire I, Barber DL. PMID: 30315137; PMCID: PMC6219716.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Formin-dependent TGF-β signaling for epithelial to mesenchymal transition. Mol Biol Cell. 2018 06 15; 29(12):1465-1475.
Rana MK, Aloisio FM, Choi C, Barber DL. PMID: 29668357; PMCID: PMC6014098.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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The Glycolytic Enzyme Phosphofructokinase-1 Assembles into Filaments. Biophysical Journal. 2018 Feb 1; 114(3):228a.
Webb WB, Dosey DA, Wittmann WT, Kollman KJ, Barber BD. .
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Cell fate decisions: emerging roles for metabolic signals and cell morphology. EMBO Rep. 2017 12; 18(12):2105-2118.
Tatapudy S, Aloisio F, Barber D, Nystul T. PMID: 29158350; PMCID: PMC5709733.
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PubMed Mentions:
48 Fields:
Translation:
Cells
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A Histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1. Elife. 2017 09 27; 6.
Vercoulen Y, Kondo Y, Iwig JS, Janssen AB, White KA, Amini M, Barber DL, Kuriyan J, Roose JP. PMID: 28952923; PMCID: PMC5643099.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins. Sci Signal. 2017 Sep 05; 10(495).
White KA, Ruiz DG, Szpiech ZA, Strauli NB, Hernandez RD, Jacobson MP, Barber DL. PMID: 28874603; PMCID: PMC6022362.
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PubMed Mentions:
35 Fields:
Translation:
HumansCells
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Prominent features of the amino acid mutation landscape in cancer. PLoS One. 2017; 12(8):e0183273.
Szpiech ZA, Strauli NB, White KA, Ruiz DG, Jacobson MP, Barber DL, Hernandez RD. PMID: 28837668; PMCID: PMC5570307.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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The glycolytic enzyme phosphofructokinase-1 assembles into filaments. J Cell Biol. 2017 08 07; 216(8):2305-2313.
Webb BA, Dosey AM, Wittmann T, Kollman JM, Barber DL. PMID: 28646105; PMCID: PMC5551713.
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PubMed Mentions:
56 Fields:
Translation:
HumansCells
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Cancer cell behaviors mediated by dysregulated pH dynamics at a glance. J Cell Sci. 2017 02 15; 130(4):663-669.
White KA, Grillo-Hill BK, Barber DL. PMID: 28202602; PMCID: PMC5339414.
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PubMed Mentions:
147 Fields:
Translation:
HumansAnimals
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Increased intracellular pH is necessary for adult epithelial and embryonic stem cell differentiation. J Cell Biol. 2016 Nov 07; 215(3):345-355.
Ulmschneider B, Grillo-Hill BK, Benitez M, Azimova DR, Barber DL, Nystul TG. PMID: 27821494; PMCID: PMC5100294.
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PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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A Histidine Cluster in the Cytoplasmic Domain of the Na-H Exchanger NHE1 Confers pH-sensitive Phospholipid Binding and Regulates Transporter Activity. J Biol Chem. 2016 Nov 11; 291(46):24096-24104.
Webb BA, White KA, Grillo-Hill BK, Schönichen A, Choi C, Barber DL. PMID: 27650500; PMCID: PMC5104935.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Structures of Human Phosphofructokinase-1 and Atomic Basis of Cancer-Associated Mutations. Biophysical Journal. 2016 Feb 1; 110(3):206a-207a.
Webb WB, Forouhar FF, Szu SF, Seetharaman SJ, Tong TL, Barber BD. .
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Abstract B65: Dissecting the tumor myeloid compartment reveals rare activating antigen presenting cells, critical for T cell immunity. Tumor Microenvironment. 2015 Oct 1; b65-b65.
Broz BM, Binnewies BM, Boldajipour BB, Nelson NA, Pollock PJ, Erle ED, Barczak BA, Rosenblum RM, Daud DA, Barber BD, Amigorena AS, Veer VL, Sperling SA, Wolf WD, Krummel KM. .
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Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations. Nature. 2015 Jul 02; 523(7558):111-4.
Webb BA, Forouhar F, Szu FE, Seetharaman J, Tong L, Barber DL. PMID: 25985179; PMCID: PMC4510984.
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PubMed Mentions:
76 Fields:
Translation:
HumansCells
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Increased H⁺ efflux is sufficient to induce dysplasia and necessary for viability with oncogene expression. Elife. 2015 Mar 20; 4.
Grillo-Hill BK, Choi C, Jimenez-Vidal M, Barber DL. PMID: 25793441; PMCID: PMC4392478.
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PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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Hypoxia increases the abundance but not the assembly of extracellular fibronectin during epithelial cell transdifferentiation. J Cell Sci. 2015 Mar 15; 128(6):1083-9.
Rana MK, Srivastava J, Yang M, Chen CS, Barber DL. PMID: 25616899; PMCID: PMC4359919.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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The Nck-interacting kinase NIK increases Arp2/3 complex activity by phosphorylating the Arp2 subunit. J Cell Biol. 2015 Jan 19; 208(2):161-70.
LeClaire LL, Rana M, Baumgartner M, Barber DL. PMID: 25601402; PMCID: PMC4298681.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity. Cancer Cell. 2014 Dec 08; 26(6):938.
Broz ML, Binnewies M, Boldajipour B, Nelson AE, Pollack JL, Erle DJ, Barczak A, Rosenblum MD, Daud A, Barber DL, Amigorena S, Van't Veer LJ, Sperling AI, Wolf DM, Krummel MF. PMID: 28898680.
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PubMed Mentions:
81 Fields:
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Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity. Cancer Cell. 2014 Nov 10; 26(5):638-52.
Broz ML, Binnewies M, Boldajipour B, Nelson AE, Pollack JL, Erle DJ, Barczak A, Rosenblum MD, Daud A, Barber DL, Amigorena S, Van't Veer LJ, Sperling AI, Wolf DM, Krummel MF. PMID: 25446897; PMCID: PMC4254577.
View in:
PubMed Mentions:
544 Fields:
Translation:
HumansAnimalsCells
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Ratiometric imaging of pH probes. Methods Cell Biol. 2014; 123:429-48.
Grillo-Hill BK, Webb BA, Barber DL. PMID: 24974041.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Filament Assembly by Phosphofructokinase-1, the Gatekeeper of Glycolysis. Biophysical Journal. 2014 Jan 1; 106(2):682a.
Webb WB, Ackerman AL, Barber BD. .
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pH Sensing by FAK-His58 Regulates Focal Adhesion Remodeling. The Journal of General Physiology. 2013 Oct 1; 142(4):1424oia30.
Choi CC, Webb WB, Chimenti CM, Jacobson JM, Barber BD. .
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pH sensing by FAK-His58 regulates focal adhesion remodeling. J Cell Biol. 2013 Sep 16; 202(6):849-59.
Choi CH, Webb BA, Chimenti MS, Jacobson MP, Barber DL. PMID: 24043700; PMCID: PMC3776353.
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PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
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Electrostatics control actin filament nucleation and elongation kinetics. J Biol Chem. 2013 Apr 26; 288(17):12102-13.
Crevenna AH, Naredi-Rainer N, Schönichen A, Dzubiella J, Barber DL, Lamb DC, Wedlich-Söldner R. PMID: 23486468; PMCID: PMC3636895.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Considering protonation as a posttranslational modification regulating protein structure and function. Annu Rev Biophys. 2013; 42:289-314.
Schönichen A, Webb BA, Jacobson MP, Barber DL. PMID: 23451893; PMCID: PMC4041481.
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PubMed Mentions:
78 Fields:
Translation:
HumansAnimalsCells
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Phosphorylation of actin-related protein 2 (Arp2) is required for normal development and cAMP chemotaxis in Dictyostelium. J Biol Chem. 2013 Jan 25; 288(4):2464-74.
Choi CH, Thomason PA, Zaki M, Insall RH, Barber DL. PMID: 23223240; PMCID: PMC3554915.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Characterization of cytoskeletal protein 4.1R interaction with NHE1 (Na(+)/H(+) exchanger isoform 1). Biochem J. 2012 Sep 15; 446(3):427-35.
Nunomura W, Denker SP, Barber DL, Takakuwa Y, Gascard P. PMID: 22731252; PMCID: PMC4338608.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Phosphorylation of the Arp2 subunit relieves auto-inhibitory interactions for Arp2/3 complex activation. PLoS Comput Biol. 2011 Nov; 7(11):e1002226.
Narayanan A, LeClaire LL, Barber DL, Jacobson MP. PMID: 22125478; PMCID: PMC3220268.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Dynamic actin remodeling during epithelial-mesenchymal transition depends on increased moesin expression. Mol Biol Cell. 2011 Dec; 22(24):4750-64.
Haynes J, Srivastava J, Madson N, Wittmann T, Barber DL. PMID: 22031288; PMCID: PMC3237619.
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PubMed Mentions:
123 Fields:
Translation:
HumansAnimalsCells
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Dysregulated pH: a perfect storm for cancer progression. Nat Rev Cancer. 2011 08 11; 11(9):671-7.
Webb BA, Chimenti M, Jacobson MP, Barber DL. PMID: 21833026.
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PubMed Mentions:
748 Fields:
Translation:
Humans
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A human MAP kinase interactome. Nat Methods. 2010 Oct; 7(10):801-5.
Bandyopadhyay S, Chiang CY, Srivastava J, Gersten M, White S, Bell R, Kurschner C, Martin C, Smoot M, Sahasrabudhe S, Barber DL, Chanda SK, Ideker T. PMID: 20936779; PMCID: PMC2967489.
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PubMed Mentions:
103 Fields:
Translation:
HumansAnimalsCells
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Nuclear-localized calcineurin homologous protein CHP1 interacts with upstream binding factor and inhibits ribosomal RNA synthesis. J Biol Chem. 2010 Nov 19; 285(47):36260-6.
Jiménez-Vidal M, Srivastava J, Putney LK, Barber DL. PMID: 20720019; PMCID: PMC2978553.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Expression of actin-interacting protein 1 suppresses impaired chemotaxis of Dictyostelium cells lacking the Na+-H+ exchanger NHE1. Mol Biol Cell. 2010 Sep 15; 21(18):3162-70.
Choi CH, Patel H, Barber DL. PMID: 20668166; PMCID: PMC2938382.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Molecular Dynamics Simulations Predict A pH-Dependent Conformational Change in the C-Helix of Cell Cycle Checkpoint Kinase Wee1. Biophysical Journal. 2010 Jan 1; 98(3):232a.
Chimenti CM, Kelly KM, Barber BD, Jacobson JM. .
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The sodium-hydrogen exchanger NHE1 is an Akt substrate necessary for actin filament reorganization by growth factors. J Biol Chem. 2009 Sep 25; 284(39):26666-75.
Meima ME, Webb BA, Witkowska HE, Barber DL. PMID: 19622752; PMCID: PMC2785354.
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PubMed Mentions:
52 Fields:
Translation:
HumansAnimalsCells
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Mislocalized scaffolding by the Na-H exchanger NHE1 dominantly inhibits fibronectin production and TGF-beta activation. Mol Biol Cell. 2009 Apr; 20(8):2327-36.
Karydis A, Jimenez-Vidal M, Denker SP, Barber DL. PMID: 19225158; PMCID: PMC2669038.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding. J Cell Biol. 2008 Dec 01; 183(5):865-79.
Frantz C, Barreiro G, Dominguez L, Chen X, Eddy R, Condeelis J, Kelly MJ, Jacobson MP, Barber DL. PMID: 19029335; PMCID: PMC2592832.
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PubMed Mentions:
101 Fields:
Translation:
HumansAnimalsCells
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Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling. Proc Natl Acad Sci U S A. 2008 Sep 23; 105(38):14436-41.
Srivastava J, Barreiro G, Groscurth S, Gingras AR, Goult BT, Critchley DR, Kelly MJ, Jacobson MP, Barber DL. PMID: 18780792; PMCID: PMC2532973.
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PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
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Phosphorylation of the Arp2/3 complex is necessary to nucleate actin filaments. J Cell Biol. 2008 Aug 25; 182(4):647-54.
LeClaire LL, Baumgartner M, Iwasa JH, Mullins RD, Barber DL. PMID: 18725535; PMCID: PMC2518704.
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PubMed Mentions:
42 Fields:
Translation:
HumansAnimalsCells
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Actin co-sedimentation assay; for the analysis of protein binding to F-actin. J Vis Exp. 2008 Mar 28; (13).
Srivastava J, Barber D. PMID: 19066573; PMCID: PMC2586866.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Positive feedback between Cdc42 activity and H+ efflux by the Na-H exchanger NHE1 for polarity of migrating cells. J Cell Biol. 2007 Nov 05; 179(3):403-10.
Frantz C, Karydis A, Nalbant P, Hahn KM, Barber DL. PMID: 17984318; PMCID: PMC2064788.
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PubMed Mentions:
53 Fields:
Translation:
AnimalsCells
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Beyond ion translocation: structural functions of the sodium-hydrogen exchanger isoform-1. Curr Opin Nephrol Hypertens. 2007 Jul; 16(4):365-72.
Meima ME, Mackley JR, Barber DL. PMID: 17565280.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
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Intracellular pH sensors: design principles and functional significance. Physiology (Bethesda). 2007 Feb; 22:30-9.
Srivastava J, Barber DL, Jacobson MP. PMID: 17289928.
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PubMed Mentions:
83 Fields:
Translation:
HumansAnimalsCells
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The Nck-interacting kinase phosphorylates ERM proteins for formation of lamellipodium by growth factors. Proc Natl Acad Sci U S A. 2006 Sep 05; 103(36):13391-6.
Baumgartner M, Sillman AL, Blackwood EM, Srivastava J, Madson N, Schilling JW, Wright JH, Barber DL. PMID: 16938849; PMCID: PMC1569174.
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PubMed Mentions:
77 Fields:
Translation:
AnimalsCells
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A developmentally regulated Na-H exchanger in Dictyostelium discoideum is necessary for cell polarity during chemotaxis. J Cell Biol. 2005 Apr 25; 169(2):321-9.
Patel H, Barber DL. PMID: 15851518; PMCID: PMC2171856.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Na(+)/H(+) exchanger NHE1 as plasma membrane scaffold in the assembly of signaling complexes. Am J Physiol Cell Physiol. 2004 Oct; 287(4):C844-50.
Baumgartner M, Patel H, Barber DL. PMID: 15355855.
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PubMed Mentions:
73 Fields:
Translation:
HumansAnimalsCells
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Expression profile of genes regulated by activity of the Na-H exchanger NHE1. BMC Genomics. 2004 Jul 16; 5(1):46.
Putney LK, Barber DL. PMID: 15257760; PMCID: PMC499544.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
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Na-H exchange-dependent increase in intracellular pH times G2/M entry and transition. J Biol Chem. 2003 Nov 07; 278(45):44645-9.
Putney LK, Barber DL. PMID: 12947095.
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PubMed Mentions:
116 Fields:
Translation:
Cells
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Conserved motifs in somatostatin, D2-dopamine, and alpha 2B-adrenergic receptors for inhibiting the Na-H exchanger, NHE1. J Biol Chem. 2003 Apr 25; 278(17):15128-35.
Lin CY, Varma MG, Joubel A, Madabushi S, Lichtarge O, Barber DL. PMID: 12566440.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1. J Cell Biol. 2002 Dec 23; 159(6):1087-96.
Denker SP, Barber DL. PMID: 12486114; PMCID: PMC2173980.
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PubMed Mentions:
194 Fields:
Translation:
AnimalsCells
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Somatostatin, acting at receptor subtype 1, inhibits Rho activity, the assembly of actin stress fibers, and cell migration. J Biol Chem. 2002 Aug 09; 277(32):28431-8.
Buchan AM, Lin CY, Choi J, Barber DL. PMID: 12045195.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Ion transport proteins anchor and regulate the cytoskeleton. Curr Opin Cell Biol. 2002 Apr; 14(2):214-20.
Denker SP, Barber DL. PMID: 11891121.
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PubMed Mentions:
44 Fields:
Translation:
HumansAnimalsCells
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The changing face of the Na+/H+ exchanger, NHE1: structure, regulation, and cellular actions. Annu Rev Pharmacol Toxicol. 2002; 42:527-52.
Putney LK, Denker SP, Barber DL. PMID: 11807182.
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PubMed Mentions:
135 Fields:
Translation:
HumansAnimalsCells
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TEL-JAK2 mediates constitutive activation of the phosphatidylinositol 3'-kinase/protein kinase B signaling pathway. J Biol Chem. 2001 Aug 31; 276(35):32704-13.
Nguyen MH, Ho JM, Beattie BK, Barber DL. PMID: 11435425.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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The Nck-interacting kinase (NIK) phosphorylates the Na+-H+ exchanger NHE1 and regulates NHE1 activation by platelet-derived growth factor. J Biol Chem. 2001 Aug 17; 276(33):31349-56.
Yan W, Nehrke K, Choi J, Barber DL. PMID: 11369779.
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PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
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A common epitope is shared by activated signal transducer and activator of transcription-5 (STAT5) and the phosphorylated erythropoietin receptor: implications for the docking model of STAT activation. Blood. 2001 Apr 15; 97(8):2230-7.
Barber DL, Beattie BK, Mason JM, Nguyen MH, Yoakim M, Neel BG, D'Andrea AD, Frank DA. PMID: 11290583.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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A minimal cytoplasmic subdomain of the erythropoietin receptor mediates p70 S6 kinase phosphorylation. Exp Hematol. 2001 Apr; 29(4):432-40.
Zhang MY, Barber DL, Alessi DR, Bell LL, Stine C, Nguyen MH, Beattie BK, Cheung JY, Miller BA. PMID: 11301183.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Direct binding of the Na--H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H(+) translocation. Mol Cell. 2000 Dec; 6(6):1425-36.
Denker SP, Huang DC, Orlowski J, Furthmayr H, Barber DL. PMID: 11163215.
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PubMed Mentions:
156 Fields:
Translation:
HumansAnimalsCells
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The SH2 inositol 5-phosphatase Ship1 is recruited in an SH2-dependent manner to the erythropoietin receptor. J Biol Chem. 2000 Feb 11; 275(6):4398-406.
Mason JM, Beattie BK, Liu Q, Dumont DJ, Barber DL. PMID: 10660611.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Effect of Rho GTPases on Na-H exchanger in mammalian cells. Methods Enzymol. 2000; 325:334-48.
Denker SP, Yan W, Barber DL. PMID: 11036616.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission. Cell. 1999 Dec 23; 99(7):769-80.
Chaudhry FA, Reimer RJ, Krizaj D, Barber D, Storm-Mathisen J, Copenhagen DR, Edwards RH. PMID: 10619430.
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PubMed Mentions:
102 Fields:
Translation:
HumansAnimalsCells
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Inhibition of calcineurin phosphatase activity by a calcineurin B homologous protein. J Biol Chem. 1999 Dec 17; 274(51):36125-31.
Lin X, Sikkink RA, Rusnak F, Barber DL. PMID: 10593895.
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PubMed Mentions:
36 Fields:
Translation:
HumansCells
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Fusion of the ets transcription factor TEL to Jak2 results in constitutive Jak-Stat signaling. Blood. 1999 Jun 15; 93(12):4354-64.
Ho JM, Beattie BK, Squire JA, Frank DA, Barber DL. PMID: 10361134.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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p160ROCK mediates RhoA activation of Na-H exchange. EMBO J. 1998 Aug 17; 17(16):4712-22.
Tominaga T, Ishizaki T, Narumiya S, Barber DL. PMID: 9707430; PMCID: PMC1170800.
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PubMed Mentions:
61 Fields:
Translation:
AnimalsCells
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Na-H exchange acts downstream of RhoA to regulate integrin-induced cell adhesion and spreading. Mol Biol Cell. 1998 Aug; 9(8):2287-303.
Tominaga T, Barber DL. PMID: 9693382; PMCID: PMC25483.
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PubMed Mentions:
61 Fields:
Translation:
AnimalsCells
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Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1. Science. 1997 Oct 03; 278(5335):124-8.
Boussiotis VA, Freeman GJ, Berezovskaya A, Barber DL, Nadler LM. PMID: 9311917.
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PubMed Mentions:
101 Fields:
Translation:
HumansCells
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Erythropoietin and interleukin-3 activate tyrosine phosphorylation of CBL and association with CRK adaptor proteins. Blood. 1997 May 01; 89(9):3166-74.
Barber DL, Mason JM, Fukazawa T, Reedquist KA, Druker BJ, Band H, D'Andrea AD. PMID: 9129019.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Erythropoietin activates Raf1 by an Shc-independent pathway in CTLL-EPO-R cells. Blood. 1997 Jan 01; 89(1):55-64.
Barber DL, Corless CN, Xia K, Roberts TM, D'Andrea AD. PMID: 8978277.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Activation of Na+-H+ exchange is necessary for RhoA-induced stress fiber formation. Journal of Biological Chemistry. 1996 Nov 1; 271(48):31008.
Vexler VZ, Symons SM, Barber BD. .
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A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange. Proc Natl Acad Sci U S A. 1996 Oct 29; 93(22):12631-6.
Lin X, Barber DL. PMID: 8901634; PMCID: PMC38044.
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PubMed Mentions:
52 Fields:
Translation:
HumansCells
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The cytokine-activated tyrosine kinase JAK2 activates Raf-1 in a p21ras-dependent manner. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11681-6.
Xia K, Mukhopadhyay NK, Inhorn RC, Barber DL, Rose PE, Lee RS, Narsimhan RP, D'Andrea AD, Griffin JD, Roberts TM. PMID: 8876196; PMCID: PMC38118.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Galpha12 differentially regulates Na+-H+ exchanger isoforms. J Biol Chem. 1996 Sep 13; 271(37):22604-10.
Lin X, Voyno-Yasenetskaya TA, Hooley R, Lin CY, Orlowski J, Barber DL. PMID: 8798430.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Activation of Na+-H+ exchange is necessary for RhoA-induced stress fiber formation. J Biol Chem. 1996 Sep 13; 271(37):22281-4.
Vexler ZS, Symons M, Barber DL. PMID: 8798382.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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A constitutively activated chimeric cytokine receptor confers factor-independent growth in hematopoietic cell lines. Blood. 1996 Jul 15; 88(2):455-64.
Shikama Y, Barber DL, D'Andrea AD, Sieff CA. PMID: 8695792.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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G alpha 13 stimulates Na+-H+ exchange through distinct Cdc42-dependent and RhoA-dependent pathways. J Biol Chem. 1996 Mar 15; 271(11):6152-8.
Hooley R, Yu CY, Symons M, Barber DL. PMID: 8626403.
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PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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[12] Regulation of Na+-H+ exchange by G protein-coupled receptors. Receptor Molecular Biology. 1995 Jan 1; 25:225-241.
Neve NK, Rosser RM, Barber BD. .
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The Fanconi anemia polypeptide FACC is localized to the cytoplasm. Proc Natl Acad Sci U S A. 1994 Jul 05; 91(14):6712-6.
Yamashita T, Barber DL, Zhu Y, Wu N, D'Andrea AD. PMID: 7517562; PMCID: PMC44273.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Subtype-specific signaling mechanisms of somatostatin receptors SSTR1 and SSTR2. J Biol Chem. 1994 Apr 08; 269(14):10357-62.
Hou C, Gilbert RL, Barber DL. PMID: 8144617.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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A dominant negative erythropoietin (EPO) receptor inhibits EPO-dependent growth and blocks F-gp55-dependent transformation. Mol Cell Biol. 1994 Apr; 14(4):2257-65.
Barber DL, DeMartino JC, Showers MO, D'Andrea AD. PMID: 8139531; PMCID: PMC358592.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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G alpha 13 stimulates Na-H exchange. J Biol Chem. 1994 Feb 18; 269(7):4721-4.
Voyno-Yasenetskaya T, Conklin BR, Gilbert RL, Hooley R, Bourne HR, Barber DL. PMID: 8106440.
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PubMed Mentions:
34 Fields:
Translation:
HumansCells
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Guanine nucleotides regulate beta-adrenergic activation of Na-H exchange independently of receptor coupling to Gs. J Biol Chem. 1992 Oct 15; 267(29):20607-12.
Barber DL, Ganz MB. PMID: 1328204.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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The erythropoietin receptor and the molecular basis of signal transduction. Semin Hematol. 1992 Oct; 29(4):293-304.
Barber DL, D'Andrea AD. PMID: 1485183.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Mutant constructs of the beta-adrenergic receptor that are uncoupled from adenylyl cyclase retain functional activation of Na-H exchange. Mol Pharmacol. 1992 Jun; 41(6):1056-60.
Barber DL, Ganz MB, Bongiorno PB, Strader CD. PMID: 1319545.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Fatty acids stereospecifically stimulate neurotensin release and increase [Ca2+]i in enteric endocrine cells. Am J Physiol. 1991 Sep; 261(3 Pt 1):G497-503.
Barber DL, Cacace AM, Raucci DT, Ganz MB. PMID: 1887896.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Mechanisms of receptor-mediated regulation of Na-H exchange. Cell Signal. 1991; 3(5):387-97.
Barber DL. PMID: 1662062.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Multiple receptors coupled to adenylate cyclase regulate Na-H exchange independent of cAMP. J Biol Chem. 1990 Jun 05; 265(16):8989-92.
Ganz MB, Pachter JA, Barber DL. PMID: 2160951.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Beta-adrenergic and somatostatin receptors regulate Na-H exchange independent of cAMP. J Biol Chem. 1989 Dec 15; 264(35):21038-42.
Barber DL, McGuire ME, Ganz MB. PMID: 2574175.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Canine enteric submucosal cultures: transmitter release from neurotensin-immunoreactive neurons. Neuroscience. 1989; 32(1):245-53.
Barber DL, Buchan AM, Leeman SE, Soll AH. PMID: 2511502.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Somatostatin and muscarinic inhibition of canine enteric endocrine cells: cellular mechanisms. Am J Physiol. 1987 Nov; 253(5 Pt 1):G684-9.
Barber DL, Gregor M, Soll AH. PMID: 2446508.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Morphologic and physiologic studies of canine ileal enteroglucagon-containing cells in short-term culture. Gastroenterology. 1987 Oct; 93(4):791-800.
Buchan AM, Barber DL, Gregor M, Soll AH. PMID: 2887480.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Cloning and sequence analysis of cDNA for the canine neurotensin/neuromedin N precursor. Proc Natl Acad Sci U S A. 1987 May; 84(10):3516-20.
Dobner PR, Barber DL, Villa-Komaroff L, McKiernan C. PMID: 3472221; PMCID: PMC304902.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Neurotensin-containing neurons in the canine enteric innervation. Neurosci Lett. 1987 Apr 23; 76(1):13-7.
Buchan AM, Barber DL. PMID: 2884606.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Chapter 9 Separation of Epithelial Cells from Gastric and Intestinal Mucosa. Cell Separation. 1987 Jan 1; 163-193.
BARBER BD, SOLL SA. .
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Regulation of neurotensin release from canine enteric primary cell cultures. Am J Physiol. 1986 Mar; 250(3 Pt 1):G385-90.
Barber DL, Buchan AM, Walsh JH, Soll AH. PMID: 2869696.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Isolated canine ileal mucosal cells in short-term culture: a model for study of neurotensin release. Am J Physiol. 1986 Mar; 250(3 Pt 1):G374-84.
Barber DL, Buchan AM, Walsh JH, Soll AH. PMID: 3513618.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells