Dyche Mullins, PhD
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Title(s) | Howard Hughes Investigator, Cellular Molecular Pharmacology |
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School | School of Medicine |
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Address | 600 16th Street San Francisco CA 94158
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Phone | 415-514-0133 |
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vCard | Download vCard |
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Overview Dyche Mullins studies the assembly and regulation of cytoskeletal networks—collections of molecules used by living cells to move molecular cargo, establish polarity, and propel themselves forward. Understanding how cells construct their internal molecular "skeletons" is key to understanding a wide variety of biological processes and human diseases.
Research ORNG Applications Bibliographic
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From solution to surface to filament: actin flux into branched networks. Biophys Rev. 2018 Dec; 10(6):1537-1551.
Mullins RD, Bieling P, Fletcher DA. PMID: 30470968.
View in: PubMed Mentions:
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WH2 and proline-rich domains of WASP-family proteins collaborate to accelerate actin filament elongation. EMBO J. 2018 01 04; 37(1):102-121.
Bieling P, Hansen SD, Akin O, Li TD, Hayden CC, Fletcher DA, Mullins RD. PMID: 29141912.
View in: PubMed Mentions: 13 Fields: Translation: HumansCells
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Cell mechanics and the cytoskeleton. Nature. 2010 Jan 28; 463(7280):485-92.
Fletcher DA, Mullins RD. PMID: 20110992.
View in: PubMed Mentions: 489 Fields: Translation: HumansAnimalsCells
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In silico reconstitution of actin-based symmetry breaking and motility. PLoS Biol. 2009 Sep; 7(9):e1000201.
Dayel MJ, Akin O, Landeryou M, Risca V, Mogilner A, Mullins RD. PMID: 19771152.
View in: PubMed Mentions: 26 Fields: Translation: HumansAnimalsCells
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Structural polymorphism of the ParM filament and dynamic instability. Structure. 2009 Sep 09; 17(9):1253-64.
Galkin VE, Orlova A, Rivera C, Mullins RD, Egelman EH. PMID: 19748346.
View in: PubMed Mentions: 20 Fields: Translation: Cells
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p53-cofactor JMY is a multifunctional actin nucleation factor. Nat Cell Biol. 2009 Apr; 11(4):451-9.
Zuchero JB, Coutts AS, Quinlan ME, Thangue NB, Mullins RD. PMID: 19287377.
View in: PubMed Mentions: 109 Fields: Translation: HumansAnimalsCells
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Bacterial Chromosome Segregation. Annu Rev Cell Dev Biol. 2009 Jan 12.
Mullins RD. PMID: 19575665.
View in: PubMed Mentions: Fields:
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Protein-nanocrystal conjugates support a single filament polymerization model in R1 plasmid segregation. J Biol Chem. 2008 Oct 17; 283(42):28081-6.
Choi CL, Claridge SA, Garner EC, Alivisatos AP, Mullins RD. PMID: 18658133.
View in: PubMed Mentions: 9 Fields: Translation: Cells
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Trapping fugitive filament formers. Structure. 2008 May; 16(5):661-3.
Mullins RD. PMID: 18462670.
View in: PubMed Mentions: Fields: Translation: AnimalsCells
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Regulatory interactions between two actin nucleators, Spire and Cappuccino. J Cell Biol. 2007 Oct 08; 179(1):117-28.
Quinlan ME, Hilgert S, Bedrossian A, Mullins RD, Kerkhoff E. PMID: 17923532.
View in: PubMed Mentions: 75 Fields: Translation: AnimalsCells
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The structure of bacterial ParM filaments. Nat Struct Mol Biol. 2007 Oct; 14(10):921-6.
Orlova A, Garner EC, Galkin VE, Heuser J, Mullins RD, Egelman EH. PMID: 17873883.
View in: PubMed Mentions: 40 Fields: Translation: Cells
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Targeted wild-type and jerker espins reveal a novel, WH2-domain-dependent way to make actin bundles in cells. J Cell Sci. 2006 Apr 15; 119(Pt 8):1655-65.
Loomis PA, Kelly AE, Zheng L, Changyaleket B, Sekerková G, Mugnaini E, Ferreira A, Mullins RD, Bartles JR. PMID: 16569662.
View in: PubMed Mentions: 18 Fields: Translation: AnimalsCells
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Cellular control of actin nucleation. Annu Rev Cell Dev Biol. 2002; 18:247-88.
Welch MD, Mullins RD. PMID: 12142287.
View in: PubMed Mentions: 159 Fields: Translation: HumansAnimalsCells
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Calcium spiking activity and baseline calcium levels in ROS 17/2.8 cells exposed to extremely low frequency electromagnetic fields (ELF EMF). Int J Radiat Biol. 2001 Feb; 77(2):241-8.
Shahidain R, Mullins RD, Sisken JE. PMID: 11236931.
View in: PubMed Mentions: 1 Fields: Translation: AnimalsCells
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Actin dynamics. J Cell Sci. 2001 Jan; 114(Pt 1):3-4.
Pollard TD, Blanchoin L, Mullins RD. PMID: 11112680.
View in: PubMed Mentions: 31 Fields: Translation: Cells
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Interactions of ADF/cofilin, Arp2/3 complex, capping protein and profilin in remodeling of branched actin filament networks. Curr Biol. 2000 Oct 19; 10(20):1273-82.
Blanchoin L, Pollard TD, Mullins RD. PMID: 11069108.
View in: PubMed Mentions: 91 Fields: Translation: AnimalsCells
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Mechanisms underlying spontaneous calcium spiking in aequorin-loaded ROS 17/2.8 cells. Bioelectromagnetics. 2000 Jul; 21(5):329-37.
Mullins RD, Sisken JE. PMID: 10899768.
View in: PubMed Mentions: Fields: Translation: AnimalsCells
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Molecular mechanisms controlling actin filament dynamics in nonmuscle cells. Annu Rev Biophys Biomol Struct. 2000; 29:545-76.
Pollard TD, Blanchoin L, Mullins RD. PMID: 10940259.
View in: PubMed Mentions: 478 Fields: Translation: HumansAnimalsCells
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Rho-family GTPases require the Arp2/3 complex to stimulate actin polymerization in Acanthamoeba extracts. Curr Biol. 1999 Apr 22; 9(8):405-15.
Mullins RD, Pollard TD. PMID: 10226024.
View in: PubMed Mentions: 21 Fields: Translation: Animals
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Structure and function of the Arp2/3 complex. Curr Opin Struct Biol. 1999 Apr; 9(2):244-9.
Mullins RD, Pollard TD. PMID: 10322212.
View in: PubMed Mentions: 29 Fields: Translation: AnimalsCells
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Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex. Proc Natl Acad Sci U S A. 1999 Mar 30; 96(7):3739-44.
Machesky LM, Mullins RD, Higgs HN, Kaiser DA, Blanchoin L, May RC, Hall ME, Pollard TD. PMID: 10097107.
View in: PubMed Mentions: 239 Fields: Translation: HumansAnimalsCells
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The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments. Proc Natl Acad Sci U S A. 1998 May 26; 95(11):6181-6.
Mullins RD, Heuser JA, Pollard TD. PMID: 9600938.
View in: PubMed Mentions: 436 Fields: Translation: AnimalsCells
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Arp2/3 complex from Acanthamoeba binds profilin and cross-links actin filaments. Mol Biol Cell. 1998 Apr; 9(4):841-52.
Mullins RD, Kelleher JF, Xu J, Pollard TD. PMID: 9529382.
View in: PubMed Mentions: 21 Fields: Translation: Animals
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Purification and assay of the Arp2/3 complex from Acanthamoeba castellanii. Methods Enzymol. 1998; 298:42-51.
Kelleher JF, Mullins RD, Pollard TD. PMID: 9751870.
View in: PubMed Mentions: 4 Fields: Translation: Animals
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Structure, subunit topology, and actin-binding activity of the Arp2/3 complex from Acanthamoeba. J Cell Biol. 1997 Jan 27; 136(2):331-43.
Mullins RD, Stafford WF, Pollard TD. PMID: 9015304.
View in: PubMed Mentions: 78 Fields: Translation: Animals
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Actin' like actin? Trends Cell Biol. 1996 Jun; 6(6):208-12.
Mullins RD, Kelleher JF, Pollard TD. PMID: 15157457.
View in: PubMed Mentions: 16 Fields:
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Serum- and bradykinin-induced calcium transients in familial Alzheimer's fibroblasts. Neurobiol Aging. 1993 Sep-Oct; 14(5):447-55.
McCoy KR, Mullins RD, Newcomb TG, Ng GM, Pavlínková G, Polinsky RJ, Nee LE, Sisken JE. PMID: 8247227.
View in: PubMed Mentions: 4 Fields: Translation: HumansCells
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Altered calcium regulation in SV40-transformed Swiss 3T3 fibroblasts. Cell Calcium. 1993 Jul; 14(7):539-49.
Newcomb TG, Mullins RD, Sisken JE. PMID: 8402837.
View in: PubMed Mentions: 5 Fields: Translation: AnimalsCells
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Design and characterization of a system for exposure of cultured cells to extremely low frequency electric and magnetic fields over a wide range of field strengths. Bioelectromagnetics. 1993; 14(2):173-86.
Mullins RD, Sisken JE, Hejase HA, Sisken BF. PMID: 8494558.
View in: PubMed Mentions: Fields: Translation: Cells
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Year | Publications |
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1993 | 3 | 1996 | 1 | 1997 | 1 | 1998 | 3 | 1999 | 3 | 2000 | 3 | 2001 | 2 | 2002 | 1 | 2006 | 1 | 2007 | 2 | 2008 | 2 | 2009 | 4 | 2010 | 1 | 2017 | 1 | 2018 | 1 |
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
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This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
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