Elaine Ku, MD
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Title(s) | Associate Professor, Medicine |
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School | School of Medicine |
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Address | 533 Parnassus Avenue San Francisco CA 94117
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Phone | 415-476-3546 |
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ORCID
.gif) | 0000-0002-7774-2526  |
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vCard | Download vCard |
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Biography University of California , Los Angeles | BA/BS | 06/2003 | English/Biology | University of California , San Diego | MD | 06/2007 | Medicine | LAC-USC Medical Center , Los Angeles | | 06/2011 | Medicine and Pediatrics Residency | University of California , San Francisco | MAS | 06/2015 | Clinical Research | University of California , San Francisco | | 06/2015 | Nephrology and Pediatric Nephrology Fellowship | University of California , San Francisco | | 2020 | Diversity, Equity, and Inclusion Champion Training |
Clinical Scientist in Nephrology Award | 2013
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| 2014 | American Kidney Fund | Young Investigator Award/Satellite Clinical Investigator | 2016
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| 2018 | National Kidney Foundation | UCSF School of Medicine | 2019 | | Inquiry Mentor Award for Outstanding Mentorship |
Overview The global context of my research program focuses on understanding differences in the epidemiology, clinical management, and outcomes of children versus adults with kidney disease and the conduct of clinical trials to test interventions (such as blood pressure control) that will improve survival of patients with kidney disease. I am especially interested in transitions of care, such as that between adolescence and young adulthood, as well as that between advanced chronic kidney disease and end-stage renal disease (including dialysis and transplant). My specific areas of focus currently include 1) cardiovascular risk in patients with kidney disease; 2) disparities in access to kidney transplantation and transplant outcomes; and 3) risk factors for progression of chronic kidney disease.
Research ORNG Applications Bibliographic
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Predicting long-term kidney allograft outcomes: pitfalls and progress. Kidney Int. 2021 01; 99(1):24-26.
Dinh A, McCulloch CE, Ku E. PMID: 33390230.
View in: PubMed Mentions: Fields: Translation: Humans
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Weighing the waitlist: Weight changes and access to kidney transplantation among obese candidates. PLoS One. 2020; 15(11):e0242784.
Ku E, Whelan AM, McCulloch CE, Lee B, Niemann CU, Roll GR, Grimes BA, Johansen KL. PMID: 33253253.
View in: PubMed Mentions: Fields: Translation: Humans
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The Kidney Failure Risk Equation for Prediction of Allograft Loss in Kidney Transplant Recipients. Kidney Med. 2020 Nov-Dec; 2(6):753-761.e1.
Chu CD, Ku E, Fallahzadeh MK, McCulloch CE, Tuot DS. PMID: 33319199.
View in: PubMed Mentions:
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Longer Distance From Dialysis Facility to Transplant Center Is Associated With Lower Access to Kidney Transplantation. Transplant Direct. 2020 Oct; 6(10):e602.
Whelan AM, Johansen KL, McCulloch CE, Adelmann D, Niemann CU, Roll GR, Siyahian S, Grimes B, Ku E. PMID: 33134482.
View in: PubMed Mentions:
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Trends in Cardiovascular Mortality Among a Cohort of Children and Young Adults Starting Dialysis in 1995 to 2015. JAMA Netw Open. 2020 Sep 01; 3(9):e2016197.
Ku E, McCulloch CE, Ahearn P, Grimes BA, Mitsnefes MM. PMID: 32902652.
View in: PubMed Mentions: Fields:
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Intensive BP Control and eGFR Declines: Are These Events Due to Hemodynamic Effects and Are Changes Reversible? Curr Cardiol Rep. 2020 Aug 09; 22(10):117.
Chen DC, McCallum W, Sarnak MJ, Ku E. PMID: 32772196.
View in: PubMed Mentions: Fields:
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Recovery of Kidney Function Among Patients With Glomerular Disease Starting Maintenance Dialysis. Am J Kidney Dis. 2020 Aug 07.
Kwong YD, Liu KD, Hsu RK, Johansen KL, McCulloch CE, Seth D, Fallahzadeh MK, Grimes BA, Ku E. PMID: 32771649.
View in: PubMed Mentions: Fields:
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eHealth in kidney care. Nat Rev Nephrol. 2020 07; 16(7):368-370.
Wang CS, Ku E. PMID: 32238923.
View in: PubMed Mentions: Fields: Translation: Humans
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Racial and Ethnic Disparities in Kidney Transplant Access Within a Theoretical Context of Medical Eligibility. Transplantation. 2020 07; 104(7):1437-1444.
Ku E, Lee BK, McCulloch CE, Roll GR, Grimes B, Adey D, Johansen KL. PMID: 31568216.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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Pretransplant dialysis exposure and outcomes after kidney transplantation - Where quantity and quality intersect? Am J Transplant. 2020 09; 20(9):2301-2302.
Dinh A, Ku E. PMID: 32406189.
View in: PubMed Mentions: Fields:
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Tubular secretion of creatinine and kidney function: an observational study. BMC Nephrol. 2020 03 30; 21(1):108.
Zhang X, Rule AD, McCulloch CE, Lieske JC, Ku E, Hsu CY. PMID: 32228497.
View in: PubMed Mentions: 3 Fields:
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Prognostic Value of Ambulatory Blood Pressure Load in Pediatric CKD. Clin J Am Soc Nephrol. 2020 04 07; 15(4):493-500.
Lee J, McCulloch CE, Flynn JT, Samuels J, Warady BA, Furth SL, Seth D, Grimes BA, Mitsnefes MM, Ku E. PMID: 32160993.
View in: PubMed Mentions: Fields:
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Association Between APOL1 Genotype and Need for Kidney Replacement Therapy in Patients Without Diabetes: Does Age Matter? Am J Kidney Dis. 2020 02; 75(2):294-296.
Wei J, Johansen KL, McCulloch CE, Lipkowitz M, Weir M, Lin F, Campese VM, Smogorzewski M, Ku E. PMID: 31837887.
View in: PubMed Mentions: Fields: Translation: Humans
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Race and Mortality in CKD and Dialysis: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Kidney Dis. 2020 03; 75(3):394-403.
Ku E, Yang W, McCulloch CE, Feldman HI, Go AS, Lash J, Bansal N, He J, Horwitz E, Ricardo AC, Shafi T, Sondheimer J, Townsend RR, Waikar SS, Hsu CY. PMID: 31732235.
View in: PubMed Mentions: 1 Fields: Translation: Humans
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Authors' Reply. J Am Soc Nephrol. 2019 12; 30(12):2474.
Winnicki E, McCulloch CE, Ku E. PMID: 31649098.
View in: PubMed Mentions: Fields: Translation: Humans
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Use of ambulatory blood pressure monitoring in kidney transplant recipients. Nephrol Dial Transplant. 2019 09 01; 34(9):1437-1439.
Whelan AM, Ku E. PMID: 30838404.
View in: PubMed Mentions: Fields: Translation: Humans
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Effect of Blood Pressure Control on Long-Term Risk of End-Stage Renal Disease and Death Among Subgroups of Patients With Chronic Kidney Disease. J Am Heart Assoc. 2019 08 20; 8(16):e012749.
Ku E, Sarnak MJ, Toto R, McCulloch CE, Lin F, Smogorzewski M, Hsu CY. PMID: 31411082.
View in: PubMed Mentions: 3 Fields: Translation: Humans
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Higher eGFR at Dialysis Initiation Is Not Associated with a Survival Benefit in Children. J Am Soc Nephrol. 2019 08; 30(8):1505-1513.
Winnicki E, Johansen KL, Cabana MD, Warady BA, McCulloch CE, Grimes B, Ku E. PMID: 31320460.
View in: PubMed Mentions: 3 Fields: Translation: Humans
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Starting Renal Replacement Therapy: Is It About Time? Am J Nephrol. 2019; 50(2):144-151.
Ku E, McCulloch CE, Johansen KL. PMID: 31269487.
View in: PubMed Mentions: Fields: Translation: Humans
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Cardiovascular disease in young adults with incident ESRD. Nat Rev Nephrol. 2019 07; 15(7):390-391.
Ku E, Mitsnefes MM. PMID: 31043718.
View in: PubMed Mentions: Fields: Translation: Humans
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Magnitude of the Difference Between Clinic and Ambulatory Blood Pressures and Risk of Adverse Outcomes in Patients With Chronic Kidney Disease. J Am Heart Assoc. 2019 05 07; 8(9):e011013.
Ku E, Hsu RK, Tuot DS, Bae SR, Lipkowitz MS, Smogorzewski MJ, Grimes BA, Weir MR. PMID: 31014164.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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Association between BMI changes and mortality risk in children with end-stage renal disease. Pediatr Nephrol. 2019 09; 34(9):1557-1563.
Roberts MJ, Mitsnefes MM, McCulloch CE, Greenbaum LA, Grimes BA, Ku E. PMID: 30963283.
View in: PubMed Mentions: Fields: Translation: Humans
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Hypertension in CKD: Core Curriculum 2019. Am J Kidney Dis. 2019 07; 74(1):120-131.
Ku E, Lee BJ, Wei J, Weir MR. PMID: 30898362.
View in: PubMed Mentions: 18 Fields: Translation: Humans
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Complications of Chronic Kidney Disease in Adolescents. Adolescents with Chronic Kidney Disease. 2019 Jan 1; 1-15.
Elaine Ku, Jonas Kwok. .
View in: Publisher Site Mentions:
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Sex Disparities in Risk of Mortality Among Children With ESRD. Am J Kidney Dis. 2019 02; 73(2):156-162.
Ahearn P, Johansen KL, McCulloch CE, Grimes BA, Ku E. PMID: 30318132.
View in: PubMed Mentions: Fields: Translation: Humans
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Depressive Symptoms Associate With Race and All-Cause Mortality in Patients With CKD. Kidney Int Rep. 2019 Feb; 4(2):222-230.
Tuot DS, Lin F, Norris K, Gassman J, Smogorzewski M, Ku E. PMID: 30775619.
View in: PubMed Mentions:
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Use of Antihypertensive Agents and Association With Risk of Adverse Outcomes in Chronic Kidney Disease: Focus on Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers. J Am Heart Assoc. 2018 10 02; 7(19):e009992.
Ku E, McCulloch CE, Vittinghoff E, Lin F, Johansen KL. PMID: 30371331.
View in: PubMed Mentions: 4 Fields: Translation: Humans
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Use of Renin-Angiotensin System Blockade in Advanced CKD: An NKF-KDOQI Controversies Report. Am J Kidney Dis. 2018 12; 72(6):873-884.
Weir MR, Lakkis JI, Jaar B, Rocco MV, Choi MJ, Kramer HJ, Ku E. PMID: 30201547.
View in: PubMed Mentions: 8 Fields: Translation: Humans
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Acute Declines in Renal Function during Intensive BP Lowering and Long-Term Risk of Death. J Am Soc Nephrol. 2018 09; 29(9):2401-2408.
Ku E, Ix JH, Jamerson K, Tangri N, Lin F, Gassman J, Smogorzewski M, Sarnak MJ. PMID: 30006417.
View in: PubMed Mentions: 1 Fields: Translation: Humans
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Time-Centered Approach to Understanding Risk Factors for the Progression of CKD. Clin J Am Soc Nephrol. 2018 05 07; 13(5):693-701.
Ku E, Johansen KL, McCulloch CE. PMID: 29602779.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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Changes in Blood Pressure During Young Adulthood and Subsequent Kidney Function Decline: Findings From the Coronary Artery Risk Development in Young Adulthood (CARDIA) Study. Am J Kidney Dis. 2018 08; 72(2):243-250.
Ku E, Vittinghoff E, Jacobs DR, Lewis CE, Allen NB, Bibbins-Domingo K, Shlipak M, Kramer H, Peralta CA. PMID: 29510922.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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Twenty-Four-Hour Ambulatory Blood Pressure versus Clinic Blood Pressure Measurements and Risk of Adverse Outcomes in Children with CKD. Clin J Am Soc Nephrol. 2018 03 07; 13(3):422-428.
Ku E, McCulloch CE, Warady BA, Furth SL, Grimes BA, Mitsnefes MM. PMID: 29440119.
View in: PubMed Mentions: 5 Fields: Translation: Humans
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Use of the Kidney Failure Risk Equation to Determine the Risk of Progression to End-stage Renal Disease in Children With Chronic Kidney Disease. JAMA Pediatr. 2018 02 01; 172(2):174-180.
Winnicki E, McCulloch CE, Mitsnefes MM, Furth SL, Warady BA, Ku E. PMID: 29255845.
View in: PubMed Mentions: 6 Fields: Translation: Humans
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Longitudinal Weight Change During CKD Progression and Its Association With Subsequent Mortality. Am J Kidney Dis. 2018 05; 71(5):657-665.
Ku E, Kopple JD, Johansen KL, McCulloch CE, Go AS, Xie D, Lin F, Hamm LL, He J, Kusek JW, Navaneethan SD, Ricardo AC, Rincon-Choles H, Smogorzewski M, Hsu CY. PMID: 29217305.
View in: PubMed Mentions: 7 Fields: Translation: Humans
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Associations Between Weight Loss, Kidney Function Decline, and Risk of ESRD in the Chronic Kidney Disease in Children (CKiD) Cohort Study. Am J Kidney Dis. 2018 05; 71(5):648-656.
Ku E, Kopple JD, McCulloch CE, Warady BA, Furth SL, Mak RH, Grimes BA, Mitsnefes M. PMID: 29132947.
View in: PubMed Mentions: 1 Fields: Translation: Humans
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Patterns of blood pressure response during intensive BP lowering and clinical events: results from the secondary prevention of small subcortical strokes trial. Blood Press. 2018 04; 27(2):73-81.
Ku E, Scherzer R, Odden MC, Shlipak M, White CL, Field TS, Benavente O, Pergola PE, Peralta CA. PMID: 28952798.
View in: PubMed Mentions: Fields: Translation: Humans
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Acute Declines in Renal Function during Intensive BP Lowering: Implications for Future ESRD Risk. J Am Soc Nephrol. 2017 Sep; 28(9):2794-2801.
Ku E, Bakris G, Johansen KL, Lin F, Sarnak MJ, Campese VM, Jamerson K, Gassman JJ, Smogorzewski M, Hsu CY. PMID: 28473636.
View in: PubMed Mentions: 11 Fields: Translation: Humans
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Racial and Ethnic Disparities in Survival of Children with ESRD. J Am Soc Nephrol. 2017 May; 28(5):1584-1591.
Ku E, McCulloch CE, Grimes BA, Johansen KL. PMID: 28034898.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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Strict blood pressure control associates with decreased mortality risk by APOL1 genotype. Kidney Int. 2017 02; 91(2):443-450.
Ku E, Lipkowitz MS, Appel LJ, Parsa A, Gassman J, Glidden DV, Smogorzewski M, Hsu CY. PMID: 27927600.
View in: PubMed Mentions: 9 Fields: Translation: Humans
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Association Between Blood Pressure and Adverse Renal Events in Type 1 Diabetes. Diabetes Care. 2016 Dec; 39(12):2218-2224.
Ku E, McCulloch CE, Mauer M, Gitelman SE, Grimes BA, Hsu CY. PMID: 27872156.
View in: PubMed Mentions: 3 Fields: Translation: Humans
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BP Control and Long-Term Risk of ESRD and Mortality. J Am Soc Nephrol. 2017 02; 28(2):671-677.
Ku E, Gassman J, Appel LJ, Smogorzewski M, Sarnak MJ, Glidden DV, Bakris G, Gutiérrez OM, Hebert LA, Ix JH, Lea J, Lipkowitz MS, Norris K, Ploth D, Pogue VA, Rostand SG, Siew ED, Sika M, Tisher CC, Toto R, Wright JT, Wyatt C, Hsu CY. PMID: 27516235.
View in: PubMed Mentions: 21 Fields: Translation: Humans
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Height at First RRT and Mortality in Children. Clin J Am Soc Nephrol. 2016 05 06; 11(5):832-9.
Ku E, Fine RN, Hsu CY, McCulloch C, Glidden DV, Grimes B, Johansen KL. PMID: 26933189.
View in: PubMed Mentions: 7 Fields: Translation: Humans
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Change in Measured GFR Versus eGFR and CKD Outcomes. J Am Soc Nephrol. 2016 Jul; 27(7):2196-204.
Ku E, Xie D, Shlipak M, Hyre Anderson A, Chen J, Go AS, He J, Horwitz EJ, Rahman M, Ricardo AC, Sondheimer JH, Townsend RR, Hsu CY. PMID: 26604213.
View in: PubMed Mentions: 12 Fields: Translation: Humans
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Association of Body Mass Index with Patient-Centered Outcomes in Children with ESRD. J Am Soc Nephrol. 2016 Feb; 27(2):551-8.
Ku E, Glidden DV, Hsu CY, Portale AA, Grimes B, Johansen KL. PMID: 26054540.
View in: PubMed Mentions: 15 Fields: Translation: Humans
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State level variations in nephrology workforce and timing and incidence of dialysis in the United States among children and adults: a retrospective cohort study. BMC Nephrol. 2015 Jan 15; 16:2.
Ku E, Johansen KL, Portale AA, Grimes B, Hsu CY. PMID: 25589150.
View in: PubMed Mentions: 6 Fields: Translation: Humans
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Association between strict blood pressure control during chronic kidney disease and lower mortality after onset of end-stage renal disease. Kidney Int. 2015 May; 87(5):1055-60.
Ku E, Glidden DV, Johansen KL, Sarnak M, Tighiouart H, Grimes B, Hsu CY. PMID: 25493952.
View in: PubMed Mentions: 23 Fields: Translation: Humans
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Index of suspicion. Case 1: fever, diarrhea, jaundice, and confusion in an 18-year-old male. Case 2: severe anemia in a 6-month-old girl. Case 3: red urine in a 4-month-old boy. Pediatr Rev. 2014 Mar; 35(3):129-35.
Ku E, Thomas M, Ho CH, Whipple NS, Abdul-Rahman O, Megason GC, Herrington BL, Carmody JB, Charlton JR. PMID: 24585816.
View in: PubMed Mentions: Fields: Translation: HumansCells
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Regional variation in the incidence of dialysis-requiring AKI in the United States. Clin J Am Soc Nephrol. 2013 Sep; 8(9):1476-81.
Hsu RK, McCulloch CE, Ku E, Dudley RA, Hsu CY. PMID: 23929923.
View in: PubMed Mentions: 18 Fields: Translation: Humans
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Is lipid management effective for all stages of CKD?. Blood Purif. 2013; 35(1-3):26-30.
Ku E, Campese V. PMID: 23343543.
View in: PubMed Mentions: Fields: Translation: Humans
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IgA nephropathy in a patient with ulcerative colitis, Graves' disease and positive myeloperoxidase ANCA. Clin Nephrol. 2012 Feb; 77(2):146-50.
Ku E, Ananthapanyasut W, Campese VM. PMID: 22257545.
View in: PubMed Mentions: 6 Fields: Translation: Humans
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Do HMG-CoA reductase inhibitors improve kidney function? The saga continues. J Nephrol. 2011 Sep-Oct; 24(5):550-3.
Campese VM, Ku E, Bigazzi R, Bianchi S. PMID: 21887675.
View in: PubMed Mentions: 3 Fields: Translation: Humans
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Metabolic and Dietary Influences on Sympathetic Nervous System Activity. Nutritional and Metabolic Bases of Cardiovascular Disease. 2011 Feb 18; 298-302.
Elaine Ku, Tanzina Nasreen, Jeanie Park, Vito M. Campese. .
View in: Publisher Site Mentions:
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Sympathetic renal innervation and resistant hypertension. Int J Hypertens. 2011 Jan 20; 2011:814354.
Campese VM, Ku E, Park J. PMID: 21331158.
View in: PubMed Mentions:
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Visual diagnosis: vaginal mass in a 16-month-old child. Pediatr Rev. 2010 Aug; 31(8):337-40.
Ku E, Brotherton BJ, Parrish C, Zia SK, McKenna S. PMID: 20679100.
View in: PubMed Mentions: Fields: Translation: Humans
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Aldosterone in the pathogenesis of chronic kidney disease and proteinuria. Curr Hypertens Rep. 2010 Aug; 12(4):303-6.
Lu Y, Ku E, Campese VM. PMID: 20596805.
View in: PubMed Mentions: 6 Fields: Translation: Humans
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Aldosterone and hypertension in African Americans. Am J Hypertens. 2009 Dec; 22(12):1234.
Ku E, Campese VM. PMID: 19924116.
View in: PubMed Mentions: 1 Fields: Translation: Humans
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The Case for Dual Renin-Angiotensin System Inhibition—Reply. JAMA Internal Medicine. 2009 Nov 9; 169(20):1931-1931.
Elaine Ku, Jeanie Park, Jay Vidhun, Vito Campese. .
View in: Publisher Site Mentions:
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Anion and osmolal gaps after alcohol intoxication. Am J Kidney Dis. 2009 Aug; 54(2):385-8.
Ku E, Cheung EL, Khan A, Yu AS. PMID: 19560850.
View in: PubMed Mentions: 1 Fields: Translation: Humans
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The hazards of dual renin-angiotensin blockade in chronic kidney disease. Arch Intern Med. 2009 Jun 08; 169(11):1015-8.
Ku E, Park J, Vidhun J, Campese V. PMID: 19506167.
View in: PubMed Mentions: Fields: Translation: Humans
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Lixivaptan: a novel vasopressin receptor antagonist. Expert Opin Investig Drugs. 2009 May; 18(5):657-62.
Ku E, Nobakht N, Campese VM. PMID: 19379124.
View in: PubMed Mentions: 5 Fields: Translation: HumansAnimals
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Role of aldosterone in the progression of chronic kidney disease and potential use of aldosterone blockade in children. Pediatr Nephrol. 2009 Dec; 24(12):2301-7.
Ku E, Campese VM. PMID: 19347366.
View in: PubMed Mentions: 2 Fields: Translation: HumansAnimals
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Year | Publications |
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2009 | 6 | 2010 | 2 | 2011 | 3 | 2012 | 1 | 2013 | 2 | 2014 | 2 | 2015 | 3 | 2016 | 5 | 2017 | 4 | 2018 | 9 | 2019 | 12 | 2020 | 11 | 2021 | 1 |
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Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
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