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Oral arsenic administration to humanizedUDP-glucuronosyltransferase1 neonatal mice induces UGT1A1 through a dependence on Nrf2 and PXR. J Biol Chem. 2023 03; 299(3):102955.
Yang X, Weber AA, Mennillo E, Paszek M, Wong S, Le S, Teo JYA, Chang M, Benner CW, Tukey RH, Chen S. PMID: 36720308; PMCID: PMC9996368.
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Animals
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Single-cell and spatial multi-omics identify innate and stromal modules targeted by anti-integrin therapy in ulcerative colitis. bioRxiv. 2023 Jan 22.
Mennillo E, Kim YJ, Rusu I, Lee G, Dorman LC, Bernard-Vazquez F, Bain JL, Patel R, Andersen C, Rao A, Tamaki S, Tsui J, Shen A, Naser M, Eckalbar W, Cho SJ, Beck K, El-Nachef N, Lewin S, Selvig DR, Terdiman JP, Mahadevan U, Oh DY, Fragiadakis GK, Pisco A, Combes AJ, Kattah MG. PMID: 36711576; PMCID: PMC9882264.
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Lactational delivery of Triclosan promotes non-alcoholic fatty liver disease in newborn mice. Nat Commun. 2022 07 27; 13(1):4346.
Weber AA, Yang X, Mennillo E, Ding J, Watrous JD, Jain M, Chen S, Karin M, Tukey RH. PMID: 35896521; PMCID: PMC9329322.
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HumansAnimalsCellsPHPublic Health
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Microbial signals, MyD88, and lymphotoxin drive TNF-independent intestinal epithelial tissue damage. J Clin Invest. 2022 03 01; 132(5).
Rusu I, Mennillo E, Bain JL, Li Z, Sun X, Ly KM, Rosli YY, Naser M, Wang Z, Advincula R, Achacoso P, Shao L, Razani B, Klein OD, Marson A, Turnbaugh JA, Turnbaugh PJ, Malynn BA, Ma A, Kattah MG. PMID: 35077396; PMCID: PMC8884902.
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5 Fields:
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HumansAnimalsCells
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Intestinal UDP-Glucuronosyltransferase 1A1 and Protection against Irinotecan-Induced Toxicity in a Novel UDP-Glucuronosyltransferase 1A1 Tissue-Specific Humanized Mouse Model. Drug Metab Dispos. 2022 01; 50(1):33-42.
Mennillo E, Yang X, Weber AA, Maruo Y, Verreault M, Barbier O, Chen S, Tukey RH. PMID: 34697081; PMCID: PMC8969198.
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2 Fields:
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HumansAnimalsCells
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Potential of therapeutic bile acids in the treatment of neonatal Hyperbilirubinemia. Sci Rep. 2021 05 27; 11(1):11107.
van der Schoor LWE, Verkade HJ, Bertolini A, de Wit S, Mennillo E, Rettenmeier E, Weber AA, Havinga R, Valášková P, Jašprová J, Struik D, Bloks VW, Chen S, Schreuder AB, Vítek L, Tukey RH, Jonker JW. PMID: 34045606; PMCID: PMC8160219.
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5 Fields:
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Animals
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Regulation of Intestinal UDP-Glucuronosyltransferase 1A1 by the Farnesoid X Receptor Agonist Obeticholic Acid Is Controlled by Constitutive Androstane Receptor through Intestinal Maturation. Drug Metab Dispos. 2021 01; 49(1):12-19.
Weber AA, Mennillo E, Yang X, van der Schoor LWE, Jonker JW, Chen S, Tukey RH. PMID: 33154041; PMCID: PMC7745083.
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1 Fields:
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HumansAnimals
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Novel organ-specific effects of Ketoprofen and its enantiomer, dexketoprofen on toxicological response transcripts and their functional products in salmon. Aquat Toxicol. 2020 Dec; 229:105677.
Mennillo E, Pretti C, Cappelli F, Luci G, Intorre L, Meucci V, Arukwe A. PMID: 33181407.
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1 Fields:
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AnimalsCells
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NCoR1 Protects Mice From Dextran Sodium Sulfate-Induced Colitis by Guarding Colonic Crypt Cells From Luminal Insult. Cell Mol Gastroenterol Hepatol. 2020; 10(1):133-147.
Mennillo E, Yang X, Paszek M, Auwerx J, Benner C, Chen S. PMID: 32044398; PMCID: PMC7229481.
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PubMed Mentions:
7 Fields:
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HumansAnimalsCells
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Differential Role of Liver X Receptor (LXR) α and LXRβ in the Regulation of UDP-Glucuronosyltransferase 1A1 in Humanized UGT1 Mice. Drug Metab Dispos. 2020 04; 48(4):255-263.
Hansmann E, Mennillo E, Yoda E, Verreault M, Barbier O, Chen S, Tukey RH. PMID: 31980500; PMCID: PMC7065491.
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4 Fields:
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Animals
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Quality screening of the Lagos lagoon sediment by assessing the cytotoxicity and toxicological responses of rat hepatoma H4IIE and fish PLHC-1 cell-lines using different extraction approaches. Environ Res. 2020 03; 182:108986.
Mennillo E, Adeogun AO, Arukwe A. PMID: 31812937.
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1 Fields:
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AnimalsCells
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Biotransformation and oxidative stress responses in rat hepatic cell-line (H4IIE) exposed to organophosphate esters (OPEs). Toxicol Appl Pharmacol. 2019 05 15; 371:84-94.
Mennillo E, Cappelli F, Arukwe A. PMID: 30974155.
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8 Fields:
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AnimalsCells
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Assessing the effects of Awba dam sediment (Nigeria) on the steroidogenesis of H295R cells using different extraction methods. Sci Total Environ. 2019 Feb 10; 650(Pt 1):121-131.
Natoli L, Luci G, Mennillo E, Adeogun AO, Arukwe A. PMID: 30196212.
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1 Fields:
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HumansCells
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Biotransformation and oxidative stress responses in rat hepatic cell-line (H4IIE) exposed to racemic ketoprofen (RS-KP) and its enantiomer, dexketoprofen (S(+)-KP). Environ Toxicol Pharmacol. 2018 Apr; 59:199-207.
Mennillo E, Krøkje Å, Pretti C, Meucci V, Arukwe A. PMID: 29626791.
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1 Fields:
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AnimalsCells
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Ecotoxicological properties of ketoprofen and the S(+)-enantiomer (dexketoprofen): Bioassays in freshwater model species and biomarkers in fish PLHC-1 cell line. Environ Toxicol Chem. 2018 01; 37(1):201-212.
Mennillo E, Arukwe A, Monni G, Meucci V, Intorre L, Pretti C. PMID: 28796322.
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5 Fields:
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AnimalsCells
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Oxidative stress responses in relationship to persistent organic pollutant levels in feathers and blood of two predatory bird species from Pakistan. Sci Total Environ. 2017 Feb 15; 580:26-33.
Abbasi NA, Arukwe A, Jaspers VLB, Eulaers I, Mennilo E, Ibor OR, Frantz A, Covaci A, Malik RN. PMID: 27939994.
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3 Fields:
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Animals
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Suitability of cholinesterase of polychaete Diopatra neapolitana as biomarker of exposure to pesticides: In vitro characterization. Comp Biochem Physiol C Toxicol Pharmacol. 2017 Jan; 191:152-159.
Mennillo E, Casu V, Tardelli F, De Marchi L, Freitas R, Pretti C. PMID: 27777085.
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2 Fields:
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AnimalsCellsPHPublic Health
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The serpulid Ficopomatus enigmaticus () as candidate organisms for ecotoxicological assays in brackish and marine waters. Ecotoxicol Environ Saf. 2018 Feb; 148:1096-1103.
Oliva M, Mennillo E, Barbaglia M, Monni G, Tardelli F, Casu V, Pretti C. PMID: 26598046.
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1 Fields:
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AnimalsCells
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Photopolymerized Network Polysiloxane Films with Dangling Hydrophilic/Hydrophobic Chains for the Biofouling Release of Invasive Marine Serpulid Ficopomatus enigmaticus. ACS Appl Mater Interfaces. 2015 Apr 22; 7(15):8293-301.
Martinelli E, Del Moro I, Galli G, Barbaglia M, Bibbiani C, Mennillo E, Oliva M, Pretti C, Antonioli D, Laus M. PMID: 25835588.
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AnimalsPHPublic Health
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An ecotoxicological study on tin- and bismuth-catalysed PDMS based coatings containing a surface-active polymer. Ecotoxicol Environ Saf. 2013 Dec; 98:250-6.
Pretti C, Oliva M, Mennillo E, Barbaglia M, Funel M, Reddy Yasani B, Martinelli E, Galli G. PMID: 24125869.
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3 Fields:
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AnimalsCellsPHPublic Health