Eugene Ozhinsky, PhD

Title(s)Associate Professor, Radiology
SchoolSchool of Medicine
Phone415-353-4932
ORCID ORCID Icon0000-0001-8993-7905 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPh.D.2012 Graduate Division (Bioengineering)
    Collapse Awards and Honors
    UCSF2006Graduate Dean's Health Science Fellowship
    INDNJC Foundation2011Surbeck Scholar Award (1st place)
    International Society for Magnetic Resonance in Medicine2014Magna Cum Laude Merit Award
    13th Annual Imaging Research Symposium, UCSF2016Outstanding Poster Presentation Award

    Collapse Overview 
    Collapse Overview
    Eugene Ozhinsky, PhD is an Associate Professor in the Department of Radiology and Biomedical Imaging, University of California San Francisco. His main research interests are in the areas of machine learning for musculoskeletal imaging and MR-guided focused ultrasound therapy.

    He is working at the VA Advanced Imaging Research Center (VAARC, part of San Francisco Veterans Affairs Health Care System) on development and implementation of machine learning techniques for automated image processing, analysis, and prescription of musculoskeletal X-ray, MRI, PET, and CT images. The goal of this work is to improve care for the VA patient population by enabling precise diagnostics, prediction of disease progression, as well as response to therapy.

    As a Technical Director for Focused Ultrasound at the Department of Radiology and Biomedical Imaging, Dr. Ozhinsky is supporting clinical focused ultrasound treatments of patients with neurological and oncological conditions. His current research focuses on safely and effectively opening of blood-brain barrier to enable delivery of therapeutics to the brain.

    Dr. Ozhinsky has obtained his PhD in the UC Berkeley/UCSF Joint Graduate Program in Bioengineering. His dissertation work was on automated acquisition of brain magnetic resonance spectroscopy data.

    Collapse Research 
    Collapse Research Activities and Funding
    Rapid, High-Resolution, Fully-Automated Metabolic Imaging for Evaluating Patients with Glioma
    Department of Defense CDMRP Department of Defense CDMRPSep 1, 2023 - Aug 31, 2027
    Role: Co-Principal Investigator
    Development of Methods for Precise MR-guided Hyperthermia Delivery for Targeted Cancer Therapies
    NIH R21EB026018Feb 1, 2019 - Dec 31, 2021
    Role: Principal Investigator

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    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Monitoring Blood-Brain Barrier Opening in Rats with a Preclinical Focused Ultrasound System. J Vis Exp. 2024 Sep 13; (211). Kim K, Gallus M, Xiao T, Parchure AS, Shah BR, Okada H, Diederich C, Ozhinsky E, Narsinh K. PMID: 39345114.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    2. Volumetric hyperthermia delivery using the ExAblate Body MR-guided focused ultrasound system. Int J Hyperthermia. 2024; 41(1):2349080. Kim K, Gupta P, Narsinh K, Diederich CJ, Ozhinsky E. PMID: 38705588; PMCID: PMC11135290.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Machine learning-based automated scan prescription of lumbar spine MRI acquisitions. Magn Reson Imaging. 2024 Jul; 110:29-34. Ozhinsky E, Liu F, Pedoia V, Majumdar S. PMID: 38574982.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Technical advances in motion-robust MR thermometry. Magn Reson Med. 2024 Jul; 92(1):15-27. Kim K, Narsinh K, Ozhinsky E. PMID: 38501903; PMCID: PMC11132643.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Shape-recovery of implanted shape-memory devices remotely triggered via image-guided ultrasound heating. Nat Commun. 2024 Feb 06; 15(1):1123. Zhu Y, Deng K, Zhou J, Lai C, Ma Z, Zhang H, Pan J, Shen L, Bucknor MD, Ozhinsky E, Kim S, Chen G, Ye SH, Zhang Y, Liu D, Gao C, Xu Y, Wang H, Wagner WR. PMID: 38321028; PMCID: PMC10847440.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    6. MR Thermometry during Transcranial MR Imaging-Guided Focused Ultrasound Procedures: A Review. AJNR Am J Neuroradiol. 2023 12 29; 45(1):1-8. Mattay RR, Kim K, Shah L, Shah B, Sugrue L, Safoora F, Ozhinsky E, Narsinh KH. PMID: 38123912; PMCID: PMC10756580.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Estimate of fetal brain temperature using proton resonance frequency thermometry during 3 Tesla fetal magnetic resonance imaging. Quant Imaging Med Surg. 2023 Dec 01; 13(12):7987-7995. Ellison J, Kim K, Li Y, Mu X, Glenn O, Ozhinsky E, Peyvandi S, Xu D. PMID: 38106288; PMCID: PMC10722078.
      View in: PubMed   Mentions:
    8. MR-guided focused ultrasound therapy of extra-abdominal desmoid tumors: a multicenter retrospective study of 105 patients. Eur Radiol. 2024 Feb; 34(2):1137-1145. Düx DM, Baal JD, Bitton R, Chen J, Brunsing RL, Sheth VR, Rosenberg J, Kim K, Ozhinsky E, Avedian R, Ganjoo K, Bucknor M, Dobrotwir A, Ghanouni P. PMID: 37615768.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    9. Magnetic Resonance Imaging of the Lumbar Spine: Recommendations for Acquisition and Image Evaluation from the BACPAC Spine Imaging Working Group. Pain Med. 2023 08 04; 24(Suppl 1):S81-S94. Sollmann N, Fields AJ, O'Neill C, Nardo L, Majumdar S, Chin CT, Tosun D, Han M, Vu AT, Ozhinsky E, Shah LM, Harris RE, Lobo R, Anderst W, Herzog R, Psioda MA, Standaert CJ, Price RT, Lotz JC, Link TM, Krug R. PMID: 36069660; PMCID: PMC10403314.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    10. Motion-robust, multi-slice, real-time MR thermometry for MR-guided thermal therapy in abdominal organs. Int J Hyperthermia. 2023; 40(1):2151649. Kim K, Diederich C, Narsinh K, Ozhinsky E. PMID: 36535967; PMCID: PMC10269483.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Technical note: Low-cost MR-compatible pneumatic respiratory organ motion simulator for the development of MR-guided thermal therapy. Med Phys. 2022 Jul; 49(7):4365-4371. Kim K, Jones P, Diederich C, Ozhinsky E. PMID: 35635215; PMCID: PMC9288488.
      View in: PubMed   Mentions: 1     Fields:    
    12. Studying osteoarthritis with artificial intelligence applied to magnetic resonance imaging. Nat Rev Rheumatol. 2022 02; 18(2):112-121. Calivà F, Namiri NK, Dubreuil M, Pedoia V, Ozhinsky E, Majumdar S. PMID: 34848883.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    13. Anatomic thermochromic tissue-mimicking phantom of the lumbar spine for pre-clinical evaluation of MR-guided focused ultrasound (MRgFUS) ablation of the facet joint. Int J Hyperthermia. 2021; 38(1):130-135. Zhang W, Trivedi H, Adams M, Losey AD, Diederich CJ, Ozhinsky E, Rieke V, Bucknor MD. PMID: 33541151.
      View in: PubMed   Mentions: 3     Fields:    
    14. Sonication strategies toward volumetric ultrasound hyperthermia treatment using the ExAblate body MRgFUS system. Int J Hyperthermia. 2021; 38(1):1590-1600. Kim K, Zubair M, Adams M, Diederich CJ, Ozhinsky E. PMID: 34749579; PMCID: PMC8806831.
      View in: PubMed   Mentions: 4     Fields:    
    15. Computer-Aided Detection AI Reduces Interreader Variability in Grading Hip Abnormalities With MRI. J Magn Reson Imaging. 2020 10; 52(4):1163-1172. Tibrewala R, Ozhinsky E, Shah R, Flament I, Crossley K, Srinivasan R, Souza R, Link TM, Pedoia V, Majumdar S. PMID: 32293775; PMCID: PMC10230649.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    16. Automatic Hip Fracture Identification and Functional Subclassification with Deep Learning. Radiol Artif Intell. 2020 Mar; 2(2):e190023. Krogue JD, Cheng KV, Hwang KM, Toogood P, Meinberg EG, Geiger EJ, Zaid M, McGill KC, Patel R, Sohn JH, Wright A, Darger BF, Padrez KA, Ozhinsky E, Majumdar S, Pedoia V. PMID: 33937815; PMCID: PMC8017394.
      View in: PubMed   Mentions: 53     Fields:    
    17. Development and Validation of a Multitask Deep Learning Model for Severity Grading of Hip Osteoarthritis Features on Radiographs. Radiology. 2020 04; 295(1):136-145. von Schacky CE, Sohn JH, Liu F, Ozhinsky E, Jungmann PM, Nardo L, Posadzy M, Foreman SC, Nevitt MC, Link TM, Pedoia V. PMID: 32013791; PMCID: PMC7104703.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    18. Wireless Resonant Circuits Printed Using Aerosol Jet Deposition for MRI Catheter Tracking. IEEE Trans Biomed Eng. 2020 03; 67(3):876-882. Jordan CD, Thorne BRH, Wadhwa A, Losey AD, Ozhinsky E, Kondapavulur S, Fratello V, Moore T, Stillson C, Yee C, Watkins RD, Scott GC, Martin AJ, Zhang X, Wilson MW, Hetts SW. PMID: 31247538; PMCID: PMC6995687.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    19. The impact of technical parameters on ablation volume during MR-guided focused ultrasound of desmoid tumors. Int J Hyperthermia. 2019; 36(1):473-476. Bucknor MD, Beroukhim G, Rieke V, Ozhinsky E, Lobach I. PMID: 30922118.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. T2 mapping as a predictor of nonperfused volume in MRgFUS treatment of desmoid tumors. Int J Hyperthermia. 2019; 36(1):1272-1277. Morochnik S, Ozhinsky E, Rieke V, Bucknor MD. PMID: 31822140; PMCID: PMC6992380.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. MR thermometry-guided ultrasound hyperthermia of user-defined regions using the ExAblate prostate ablation array. J Ther Ultrasound. 2018; 6:7. Ozhinsky E, Salgaonkar VA, Diederich CJ, Rieke V. PMID: 30123506; PMCID: PMC6088423.
      View in: PubMed   Mentions: 12  
    22. Effect of Sonication Duration and Power on Ablation Depth During MR-Guided Focused Ultrasound of Bone. J Magn Reson Imaging. 2017 11; 46(5):1418-1422. Bucknor MD, Ozhinsky E, Shah R, Krug R, Rieke V. PMID: 28225581.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    23. T2-based temperature monitoring in bone marrow for MR-guided focused ultrasound. J Ther Ultrasound. 2016; 4:26. Ozhinsky E, Han M, Bucknor M, Krug R, Rieke V. PMID: 27882240; PMCID: PMC5112680.
      View in: PubMed   Mentions: 6  
    24. Quantifying temperature-dependent T1 changes in cortical bone using ultrashort echo-time MRI. Magn Reson Med. 2015 Dec; 74(6):1548-55. Han M, Rieke V, Scott SJ, Ozhinsky E, Salgaonkar VA, Jones PD, Larson PE, Diederich CJ, Krug R. PMID: 26390357; PMCID: PMC4715675.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    25. T2-based temperature monitoring in abdominal fat during MR-guided focused ultrasound treatment of patients with uterine fibroids. J Ther Ultrasound. 2015; 3:15. Ozhinsky E, Kohi MP, Ghanouni P, Rieke V. PMID: 26366288; PMCID: PMC4567827.
      View in: PubMed   Mentions: 9  
    26. Short-echo three-dimensional H-1 MR spectroscopic imaging of patients with glioma at 7 Tesla for characterization of differences in metabolite levels. J Magn Reson Imaging. 2015 May; 41(5):1332-41. Li Y, Larson P, Chen AP, Lupo JM, Ozhinsky E, Kelley D, Chang SM, Nelson SJ. PMID: 24935758; PMCID: PMC4269580.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    27. Model-based feasibility assessment and evaluation of prostate hyperthermia with a commercial MR-guided endorectal HIFU ablation array. Med Phys. 2014 Mar; 41(3):033301. Salgaonkar VA, Prakash P, Rieke V, Ozhinsky E, Plata J, Kurhanewicz J, Hsu IC, Diederich CJ. PMID: 24593742; PMCID: PMC3987720.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    28. Strategies for rapid in vivo 1H and hyperpolarized 13C MR spectroscopic imaging. J Magn Reson. 2013 Apr; 229:187-97. Nelson SJ, Ozhinsky E, Li Y, Park Iw, Crane J. PMID: 23453759; PMCID: PMC3808990.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    29. Automated prescription of oblique brain 3D magnetic resonance spectroscopic imaging. Magn Reson Med. 2013 Apr; 69(4):920-30. Ozhinsky E, Vigneron DB, Chang SM, Nelson SJ. PMID: 22692829; PMCID: PMC3443494.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    30. Prospective image registration for automated scan prescription of follow-up knee images in quantitative studies. Magn Reson Imaging. 2011 Jun; 29(5):693-700. Goldenstein J, Schooler J, Crane JC, Ozhinsky E, Pialat JB, Carballido-Gamio J, Majumdar S. PMID: 21546186; PMCID: PMC3100398.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    31. Improved spatial coverage for brain 3D PRESS MRSI by automatic placement of outer-volume suppression saturation bands. J Magn Reson Imaging. 2011 Apr; 33(4):792-802. Ozhinsky E, Vigneron DB, Nelson SJ. PMID: 21448942; PMCID: PMC3071575.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    32. Volumetric cartilage measurements of porcine knee at 1.5-T and 3.0-T MR imaging: evaluation of precision and accuracy. Radiology. 2006 Nov; 241(2):399-406. Bauer JS, Krause SJ, Ross CJ, Krug R, Carballido-Gamio J, Ozhinsky E, Majumdar S, Link TM. PMID: 17057067.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    33. Computer-aided quantification of focal cartilage lesions of osteoarthritic knee using MRI. Magn Reson Imaging. 2004 Oct; 22(8):1105-15. Lee KY, Dunn TC, Steinbach LS, Ozhinsky E, Ries MD, Majumdar S. PMID: 15527997.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    34. A new computational efficient approach for trabecular bone analysis using beam models generated with skeletonized graph technique. Comput Methods Biomech Biomed Engin. 2004 Aug; 7(4):205-13. Pothuaud L, Van Rietbergen B, Charlot C, Ozhinsky E, Majumdar S. PMID: 15512764.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    35. A three-dimensional MRI analysis of knee kinematics. J Orthop Res. 2004 Mar; 22(2):283-92. Patel VV, Hall K, Ries M, Lotz J, Ozhinsky E, Lindsey C, Lu Y, Majumdar S. PMID: 15013086.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    36. Magnetic resonance imaging of patellofemoral kinematics with weight-bearing. J Bone Joint Surg Am. 2003 Dec; 85(12):2419-24. Patel VV, Hall K, Ries M, Lindsey C, Ozhinsky E, Lu Y, Majumdar S. PMID: 14668513.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
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