Dr. Sugrue is an Assistant Professor in Residence and Attending Neuroradiologist in the Neuroradiology section of the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. Together with Dr. Rahul Desikan, Dr. Sugrue co-directs the Laboratory for Precision Neuroimaging at UCSF.

As a neuroscientist and clinical neuroradiologist, Dr. Sugrue’s goal is to develop new tools for imaging, measuring, and modifying brain activity, and to translate these tools from the lab to the clinic where they can improve the prediction, diagnosis, and treatment of brain disease. Dr. Sugrue and his team work on a range of research projects that share the common theme of combining different types of data to better understand the underlying cause of brain disease in individual patients.

These include projects aimed at understanding how the balance of activity across networks of brain areas may contribute to conditions such as obsessive compulsive disorder (OCD) and Huntington’s disease (HD), as well as projects that combine brain imaging with genetic, physiologic, and behavioral markers to better understand neurodegenerative and neurodevelopmental disorders. In an example of this approach, his team’s recent work on frontotemporal dementia (FTD) combined genome-wide association studies with gene expression data to demonstrate a link between certain subtypes of FTD and immune dysfunction. Moving forward the team hopes build on this work by developing methods to directly image neuroinflammation in the brain as a biomarker of disease risk and progression in FTD and other neurodegenerative diseases including ALS.

Expertise:
Neuroradiology

Specialty:
Neuroradiology, Cognitive and Systems Neuroscience, Multimodal brain imaging

Professional Interests:
Imaging of neuropsychiatric disease, imaging genetics, systems-computational-cognitive neuroscience, neural basis of decision making and the influence of reward and valuation on choice behavior, brain-machine interface technologies. Functional MRI (fMRI), electrocorticography (ECOG), magnetoencephalography (MEG), transcranial magnetic stimulation (TMS), brain MR guided focused-ultrasound (MRg-FUS), functional connectivity MRI (fcMRI).

Education and Training:
• Medical School: The Johns Hopkins University School of Medicine, Baltimore, MD – Medicine
• Doctor of Philosophy: Stanford University School of Medicine, CA – Neuroscience
• Internship: Stanford Hospital and Clinics, CA – Internal Medicine
• Post-Doctoral Fellowship: Howard Hughes Institute at Stanford University, CA – Neuroscience
• Residency: University of California, San Francisco – Diagnostic Radiology
• Fellowship: University of California, San Francisco – Diagnostic Neuroradiology
• Fellowship University of California, San Francisco – ACGME Neuroradiology
• California Medical License
• American Board of Radiology Certificate in Diagnostic Radiology