Leo Sugrue, MD, PhD

TitleAssistant Professor
InstitutionUniversity of California San Francisco
Address185 Berry Street Bldg B
San Francisco CA 94158
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    Collapse Biography 
    Collapse Awards and Honors
    Association of University Radiologists2011Siemens AUR Radiology Resident Academic Development (SARRAD) Program

    Collapse Overview 
    Collapse Overview
    Leo Sugrue, MD, PhD, is an Assistant Professor in Residence at the University of California, San Francisco in the Department of Radiology and Biomedical Imaging. He received his medical degree from The Johns Hopkins University School of Medicine in 2007. In 2008, he completed his PhD in Neuroscience from Stanford University School of Medicine in California, where he completed a one-year internal medicine internship the same year. In 2009, Dr. Sugrue finished a post-doctoral fellowship at Howard Hughes Medical Institute, Stanford University, and in 2013 he completed a four-year Diagnostic Radiology residency at UCSF. Dr. Sugrue finished a five-month mini-fellowship in diagnostic neuroradiology in 2013, followed by an ACGME Neuroradiology fellowship in the Department of Radiology and Biomedical Imaging at UCSF in 2014.

    Dr. Sugrue’s interests focus on using electrophysiological and imaging-based tools to study the brain networks responsible for decision making and cognition, developing imaging biomarkers to diagnose and treat neuropsychiatric disease, and targeting and evaluating brain stimulation and brain-machine interface technologies. In September 2014, he accepted the position of Assistant Professor in Residence in Neuroradiology at UCSF.


    Neuroradiology, Cognitive and Systems Neuroscience, Functional brain imaging

    Professional Interests:
    Functional brain imaging, imaging of neuropsychiatric disease, systems and computational neuroscience, cognitive and behavioral neuroscience, neural basis of decision making and the influence of reward and valuation on choice behavior, neuroengineering and brain-machine interface technologies, animal neurophysiology, invasive and noninvasive electrical brain stimulation, human functional MRI (fMRI), electrocorticography (ECOG), magnetoencephalography (MEG), transcranial magnetic stimulation (TMS), diffusion tensor imaging (DTI), functional connectivity MRI (fcMRI)

    Education and Training:
    • Medical School: The Johns Hopkins University School of Medicine, Baltimore, MD – Medicine
    • Doctor of Philosophy: Stanford University School of Medicine, CA – Neuroscience
    • Internship: Stanford Hospital and Clinics, CA – Internal Medicine
    • Residency: University of California, San Francisco – Diagnostic Radiology
    • Fellowship: University of California, San Francisco – Diagnostic Neuroradiology
    • Fellowship University of California, San Francisco – ACGME Neuroradiology
    • California Medical License
    • American Board of Radiology Certificate in Diagnostic Radiology

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Bonham LW, Karch CM, Fan CC, Tan C, Geier EG, Wang Y, Wen N, Broce IJ, Li Y, Barkovich MJ, Ferrari R, Hardy J, Momeni P, Höglinger G, Müller U, Hess CP, Sugrue L, Dillon WP, Schellenberg GD, Miller BL, Andreassen OA, Dale AM, Barkovich AJ, Yokoyama JS, Desikan RS. CXCR4 involvement in neurodegenerative diseases. Transl Psychiatry. 2018 Apr 11; 8(1):73. PMID: 29636460.
      View in: PubMed
    2. Southwell DG, Birk HS, Larson PS, Starr PA, Sugrue L, Auguste KI. Laser ablative therapy of sessile hypothalamic hamartomas in children using interventional MRI: report of 5 cases. J Neurosurg Pediatr. 2018 Feb 16; 1-6. PMID: 29451455.
      View in: PubMed
    3. Broce I, Karch CM, Wen N, Fan CC, Wang Y, Tan CH, Kouri N, Ross OA, Höglinger GU, Muller U, Hardy J. Correction: Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies. PLoS Med. 2018 Jan; 15(1):e1002504. PMID: 29377952.
      View in: PubMed
    4. Broce I, Karch CM, Wen N, Fan CC, Wang Y, Tan CH, Kouri N, Ross OA, Höglinger GU, Muller U, Hardy J. Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies. PLoS Med. 2018 01; 15(1):e1002487. PMID: 29315334.
      View in: PubMed
    5. Tan CH, Fan CC, Mormino EC, Sugrue L, Broce IJ, Hess CP, Dillon WP, Bonham LW, Yokoyama JS, Karch CM, Brewer JB, Rabinovici GD, Miller BL, Schellenberg GD, Kauppi K, Feldman HA, Holland D, McEvoy LK, Hyman BT, Bennett DA, Andreassen OA, Dale AM, Desikan RS. Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition. Acta Neuropathol. 2018 Jan; 135(1):85-93. PMID: 29177679.
      View in: PubMed
    6. Tong E, Sugrue L, Wintermark M. Understanding the Neurophysiology and Quantification of Brain Perfusion. Top Magn Reson Imaging. 2017 Apr; 26(2):57-65. PMID: 28277465.
      View in: PubMed
    7. Yokoyama JS, Karch CM, Fan CC, Bonham LW, Kouri N, Ross OA, Rademakers R, Kim J, Wang Y, Höglinger GU, Müller U, Ferrari R, Hardy J. Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia. Acta Neuropathol. 2017 May; 133(5):825-837. PMID: 28271184.
      View in: PubMed
    8. Ferrari R, Wang Y, Vandrovcova J, Guelfi S, Witeolar A, Karch CM, Schork AJ, Fan CC, Brewer JB. Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases. J Neurol Neurosurg Psychiatry. 2017 02; 88(2):152-164. PMID: 27899424.
      View in: PubMed
    9. Yu JP, Barajas RF, Olorunsola D, Sugrue L, Hernandez-Pampaloni M. Heterogeneous 18F-FDG uptake in recurrent respiratory papillomatosis. Clin Nucl Med. 2013 May; 38(5):387-9. PMID: 23486321.
      View in: PubMed
    10. Churchland MM, Yu BM, Cunningham JP, Sugrue L, Cohen MR, Corrado GS, Newsome WT, Clark AM, Hosseini P, Scott BB, Bradley DC, Smith MA, Kohn A, Movshon JA, Armstrong KM, Moore T, Chang SW, Snyder LH, Lisberger SG, Priebe NJ, Finn IM, Ferster D, Ryu SI, Santhanam G, Sahani M, Shenoy KV. Stimulus onset quenches neural variability: a widespread cortical phenomenon. Nat Neurosci. 2010 Mar; 13(3):369-78. PMID: 20173745; PMCID: PMC2828350.
    11. Corrado GS, Sugrue L, Seung HS, Newsome WT. Linear-Nonlinear-Poisson models of primate choice dynamics. J Exp Anal Behav. 2005 Nov; 84(3):581-617. PMID: 16596981; PMCID: PMC1389782.
    12. Sugrue L, Corrado GS, Newsome WT. Choosing the greater of two goods: neural currencies for valuation and decision making. Nat Rev Neurosci. 2005 May; 6(5):363-75. PMID: 15832198.
      View in: PubMed
    13. Sugrue L, Corrado GS, Newsome WT. Matching behavior and the representation of value in the parietal cortex. Science. 2004 Jun 18; 304(5678):1782-7. PMID: 15205529.
      View in: PubMed