Farid Chehab, PhD

Title(s)Professor, Laboratory Medicine
SchoolSchool of Medicine
Address185 Berry Street Bldg B
San Francisco CA 94158
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    NIH R01HD035142May 1, 1998 - Apr 30, 2004
    Role: Principal Investigator
    NIH P01HL053762Sep 30, 1994 - Aug 31, 2007
    Role: Co-Investigator
    NIH P30DK047766Sep 30, 1993 - Aug 31, 1999
    Role: Co-Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Spontaneous splenic rupture: A rare complication of acute myeloid leukemia. Report of a case. Ann Med Surg (Lond). 2021 May; 65:102286. Hajri A, Yaqine K, El Massi S, Errguibi D, Boufettal R, El Jai SR, Chehab F. PMID: 34026095.
      View in: PubMed   Mentions:
    2. Non-functional retroperitoneal paraganglioma: A report of case with literature review. Ann Med Surg (Lond). 2021 May; 65:102360. Hajri A, Ballati A, Essaidi Z, Errguibi D, Boufettal R, Rifki El Jai S, Chehab F. PMID: 34007447.
      View in: PubMed   Mentions:
    3. Retrorectal cystic hamartoma: A case report. Ann Med Surg (Lond). 2021 Jun; 66:102362. El Yamine O, Fatine A, Boufettal R, Errguibi D, Hajri A, Rifki El Jay S, Chehab F. PMID: 34040764.
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    4. Postsurgical Diagnosis of an Unusual Case of Primary Hepatic Lymphoma Presenting as Liver Abscess with an Uncommon Complication: A Hepatogastric Fistula. Case Rep Hematol. 2021; 2021:6647558. Yaka M, Chehab F, Allaoui M, Ait Ali A, Zentar A. PMID: 33680521.
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    5. A gastrointestinal stromal tumor of stomach presenting with an intratumoral abscess: A case report. Ann Med Surg (Lond). 2021 Mar; 63:102143. Ballati A, Essaidi Z, El Attar L, Errguibi D, Hajri A, Boufettal R, El Jai SR, Chehab F. PMID: 33643648.
      View in: PubMed   Mentions:
    6. Molecular and phenotypic diversity of CBL-mutated juvenile myelomonocytic leukemia. Haematologica. 2020 12 30; Online ahead of print. Hecht A, Meyer JA, Behnert A, Wong E, Chehab F, Olshen A, Hechmer A, Aftandilian C, Bhat R, Choi SW, Chonat S, Farrar JE, Fluchel M, Frangoul H, Han JH, Kolb EA, Kuo DJ, MacMillan ML, Maese L, Maloney KW, Narendran A, Oshrine B, Schultz KR, Sulis ML, Van Mater D, Tasian SK, Hofmann WK, Loh ML, Stieglitz E. PMID: 33375775.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Molecular assessment of pretransplant chemotherapy in the treatment of juvenile myelomonocytic leukemia. Pediatr Blood Cancer. 2019 11; 66(11):e27948. Hecht A, Meyer J, Chehab FF, White KL, Magruder K, Dvorak CC, Loh ML, Stieglitz E. PMID: 31347788.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. PAX5, NOTCH3, CBFB, and ACD drive an activated RAS pathway and monosomy 7 to B-ALL and AML in donor cell leukemia. Bone Marrow Transplant. 2019 07; 54(7):1124-1128. Assi R, Mahfouz R, Owen R, Gunthorpe M, Chehab FF, Bazarbachi A. PMID: 30532056.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsCTClinical Trials
    9. [Laparoscopic cholecystectomy in a patient with situs inversus]. Pan Afr Med J. 2018; 31:183. Boufettal R, Erguibi D, Hajri A, Idrissi A, Jai SR, Chehab F. PMID: 31065323.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Upregulation of cholesterol 24-hydroxylase following hypoxia-ischemia in neonatal mouse brain. Pediatr Res. 2018 06; 83(6):1218-1227. Lu F, Zhu J, Guo S, Wong BJ, Chehab FF, Ferriero DM, Jiang X. PMID: 29718007.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    11. Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia. Nat Commun. 2017 12 19; 8(1):2127. Stieglitz E, Mazor T, Olshen AB, Geng H, Gelston LC, Akutagawa J, Lipka DB, Plass C, Flotho C, Chehab FF, Braun BS, Costello JF, Loh ML. PMID: 29259179.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsCTClinical Trials
    12. PATH-08. THE PROGNOSTIC VALUE OF A NOVEL QUANTITATIVE MGMT PROMOTER METHYLATION SCORE FOR PATIENTS WITH GLIOBLASTOMA. Neuro-Oncology. 2017 Nov 6; 19(suppl_6):vi172-vi172. Akshay Ravi, Annette Molinaro, Seunggu J Han, Farid Chehab, Mitchel S Berger, Nicholas Butowski. .
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    13. Risk of colorectal cancer and clotting factor gene polymorphisms in Moroccan Population. Int J Adv Res (Indore). 2017; 5(8):1141-1146. Baghad I, Erguibi D, Chehab F, Nadifi S. PMID: 29354651.
      View in: PubMed   Mentions:
    14. MPTH-25. THE PROGNOSTIC VALUE OF A NOVEL QUANTITATIVE MGMT PROMOTER METHYLATION SCORE FOR PATIENTS WITH GLIOBLASTOMA. Neuro-Oncology. 2016 Nov 1; 18(suppl_6):vi111-vi111. Seunggu Han, Akshay Ravi, Annette Molinaro, Jennie Taylor, Jennifer Clarke, Nancy Ann Oberheim-Bush, Susan Chang, Mitchel S. Berger, Farid Chehab, Nicholas Butowski. .
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    15. Pleomorphous leiomyosarcoma of the mesocolon: a case report. Pan Afr Med J. 2015; 22:322. Jai SR, Farah RH, Hamdaoui B, Boufettal R, Chehab F. PMID: 26977231.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Videocapsule retention: role of surgical treatment (a case report). Pan Afr Med J. 2015; 22:64. Boufettal R, Fahmi Y, Jai SR, Chehab F. PMID: 26834917.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. [Pancreatic hydatid cyst: a case about]. Pan Afr Med J. 2015; 21:273. Eljai RS, Boufettal R, Farah RH, Chehab F. PMID: 26587123.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. [Pancreatic heterotopia as an unusual cause of upper gastrointestinal bleeding]. Presse Med. 2015 Mar; 44(3):368-9. Boufettal R, Elbakouri A, Jai SR, Chehab F. PMID: 25534468.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. First report of a deletion encompassing an entire exon in the homogentisate 1,2-dioxygenase gene causing alkaptonuria. PLoS One. 2014; 9(9):e106948. Zouheir Habbal M, Bou-Assi T, Zhu J, Owen R, Chehab FF. PMID: 25233259.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    20. 20 years of leptin: leptin and reproduction: past milestones, present undertakings, and future endeavors. J Endocrinol. 2014 Oct; 223(1):T37-48. Chehab FF. PMID: 25118207.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    21. FoxO4 interacts with the sterol regulatory factor SREBP2 and the hypoxia inducible factor HIF2a at the CYP51 promoter. J Lipid Res. 2014 Mar; 55(3):431-42. Zhu J, Jiang X, Chehab FF. PMID: 24353279.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    22. Duplication of C7orf58, WNT16 and FAM3C in an obese female with a t(7;22)(q32.1;q11.2) chromosomal translocation and clinical features resembling Coffin-Siris Syndrome. PLoS One. 2012; 7(12):e52353. Zhu J, Qiu J, Magrane G, Abedalthagafi M, Zanko A, Golabi M, Chehab FF. PMID: 23300646.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    23. Homozygous deletion of six olfactory receptor genes in a subset of individuals with Beta-thalassemia. PLoS One. 2011 Feb 24; 6(2):e17327. Van Ziffle J, Yang W, Chehab FF. PMID: 21390308.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    24. Chapter 36 Molecular Diagnostic Challenges of the Thalassemias. Molecular Diagnostics. 2010 Jan 1; 441-452. Farid F. Chehab. .
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    25. Effects of FoxO4 overexpression on cholesterol biosynthesis, triacylglycerol accumulation, and glucose uptake. J Lipid Res. 2010 Jun; 51(6):1312-24. Zhu J, Mounzih K, Chehab EF, Mitro N, Saez E, Chehab FF. PMID: 20037138.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    26. Overexpression of the transcription factor Foxo4 is associated with rapid glucose clearance. Mol Cell Endocrinol. 2009 Aug 13; 307(1-2):217-23. Wang B, Zhu J, Mounzih K, Chehab EF, Ke Y, Chehab FF. PMID: 19410631.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    27. Obesity and lipodystrophy--where do the circles intersect? Endocrinology. 2008 Mar; 149(3):925-34. Chehab FF. PMID: 18202137.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    28. Deletion of the serotonin 2c receptor from transgenic mice overexpressing leptin does not affect their lipodystrophy but exacerbates their diet-induced obesity. Biochem Biophys Res Commun. 2006 Dec 15; 351(2):418-23. Wang B, Chehab FF. PMID: 17064660.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    29. Mosaicism for a full mutation, premutation, and deletion of the CGG repeats results in 22% FMRP and elevated FMR1 mRNA levels in a high-functioning fragile X male. . 2006 Jul 01; 140(13):1463-71. Han XD, Powell BR, Phalin JL, Chehab FF. PMID: 16761284.
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    30. The use of animal models to dissect the biology of leptin. Recent Prog Horm Res. 2004; 59:245-66. Chehab FF, Qiu J, Ogus S. PMID: 14749505.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    31. Overexpression of leptin in transgenic mice leads to decreased basal lipolysis, PKA activity, and perilipin levels. Biochem Biophys Res Commun. 2003 Dec 26; 312(4):1165-70. Ke Y, Qiu J, Ogus S, Shen WJ, Kraemer FB, Chehab FF. PMID: 14651995.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    32. Hyperleptinemia precipitates diet-induced obesity in transgenic mice overexpressing leptin. Endocrinology. 2003 Jul; 144(7):2865-9. Ogus S, Ke Y, Qiu J, Wang B, Chehab FF. PMID: 12810541.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    33. Genetics and Physiology Link Leptin to the Reproductive System. Leptin and Reproduction. 2003 Jan 1; 267-286. Farid F. Chehab, Amanda Ewart-Toland, Khalid Mounzih, Jun Qiu, Scott Ogus. .
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    34. Leptin and reproduction. Nutr Rev. 2002 Oct; 60(10 Pt 2):S39-46; discussion S68-84, 85-7. Chehab FF, Qiu J, Mounzih K, Ewart-Toland A, Ogus S. PMID: 12403083.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    35. Leptin-deficient mice backcrossed to the BALB/cJ genetic background have reduced adiposity, enhanced fertility, normal body temperature, and severe diabetes. Endocrinology. 2001 Aug; 142(8):3421-5. Qiu J, Ogus S, Mounzih K, Ewart-Toland A, Chehab FF. PMID: 11459786.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    36. Transgenic mice overexpressing leptin accumulate adipose mass at an older, but not younger, age. Endocrinology. 2001 Jan; 142(1):348-58. Qiu J, Ogus S, Lu R, Chehab FF. PMID: 11145598.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    37. Leptin as a regulator of adipose mass and reproduction. Trends Pharmacol Sci. 2000 Aug; 21(8):309-14. Chehab FF. PMID: 10918637.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    38. Effect of the genetic background on the reproduction of leptin-deficient obese mice. Endocrinology. 1999 Feb; 140(2):732-8. Ewart-Toland A, Mounzih K, Qiu J, Chehab FF. PMID: 9927300.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    39. Leptin is not necessary for gestation and parturition but regulates maternal nutrition via a leptin resistance state. Endocrinology. 1998 Dec; 139(12):5259-62. Mounzih K, Qiu J, Ewart-Toland A, Chehab FF. PMID: 9832467.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    40. Leptin treatment rescues the sterility of genetically obese ob/ob males. Endocrinology. 1997 Mar; 138(3):1190-3. Mounzih K, Lu R, Chehab FF. PMID: 9048626.
      View in: PubMed   Mentions: 83     Fields:    Translation:Animals
    41. Early onset of reproductive function in normal female mice treated with leptin. Science. 1997 Jan 03; 275(5296):88-90. Chehab FF, Mounzih K, Lu R, Lim ME. PMID: 8974400.
      View in: PubMed   Mentions: 90     Fields:    Translation:Animals
    42. Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nat Genet. 1996 Mar; 12(3):318-20. Chehab FF, Lim ME, Lu R. PMID: 8589726.
      View in: PubMed   Mentions: 234     Fields:    Translation:HumansAnimalsCells
    43. New frameshift mutation, insertion of A, at codon 95 of the beta-globin gene causes beta-thalassemia in two Vietnamese families. Hum Mutat. 1996; 8(3):293-4. Cai S, Chehab FF. PMID: 8889595.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    44. Methylation status of CpG sites in the mouse and human CFTR promoters. DNA Cell Biol. 1995 Sep; 14(9):811-5. Denamur E, Chehab FF. PMID: 7545404.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    45. A 31-mutation assay for cystic fibrosis testing in the clinical molecular diagnostics laboratory. Hum Mutat. 1995; 5(4):333-8. Wall J, Cai S, Chehab FF. PMID: 7627189.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    46. 10 Analysis of PCR Products by Covalent Reverse Dot Blot Hybridization. PCR Strategies. 1995 Jan 1; 130-139. Farid F. Chehab, Jeff Wall, Shi-ping Cai. .
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    47. Analysis of the mouse and rat CFTR promoter regions. Hum Mol Genet. 1994 Jul; 3(7):1089-94. Denamur E, Chehab FF. PMID: 7526924.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    48. A new frameshift mutation, insertion of ATCT, at codon 48 in the beta-globin gene causes beta-thalassemia in an Indian proband. Hum Mutat. 1994; 3(4):397-8. Jain PK, Dozy AM, Verma IC, Chehab FF. PMID: 8081396.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    49. Reverse dot blot probes for the screening of beta-thalassemia mutations in Asians and American blacks. Hum Mutat. 1994; 3(1):59-63. Cai SP, Wall J, Kan YW, Chehab FF. PMID: 8118466.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    50. Molecular diagnostics: past, present, and future. Hum Mutat. 1993; 2(5):331-7. Chehab FF. PMID: 8257984.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    51. Rapid and simultaneous typing of hemoglobin S, hemoglobin C, and seven Mediterranean beta-thalassemia mutations by covalent reverse dot-blot analysis: application to prenatal diagnosis in Sicily. Blood. 1993 Jan 1; 81(1):239-242. A Maggio, A Giambona, SP Cai, J Wall, YW Kan, FF Chehab. .
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    52. Detection of multiple cystic fibrosis mutations by reverse dot blot hybridization: a technology for carrier screening. Hum Genet. 1992 May; 89(2):163-8. Chehab FF, Wall J. PMID: 1587526.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    53. Amplification and detection of specific DNA sequences with fluorescent PCR primers: application to delta F508 mutation in cystic fibrosis. Methods Enzymol. 1992; 216:135-43. Chehab FF, Wall J, Kan YW. PMID: 1479898.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    54. A dimorphic 4-bp repeat in the cystic fibrosis gene is in absolute linkage disequilibrium with the delta F508 mutation: implications for prenatal diagnosis and mutation origin. Am J Hum Genet. 1991 Feb; 48(2):223-6. Chehab FF, Johnson J, Louie E, Goossens M, Kawasaki E, Erlich H. PMID: 1990833.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    55. Detection of the hemoglobin E mutation using the color complementation assay: application to complex genotyping. Blood. 1990 Aug 1; 76(3):619-623. SH Embury, GL Kropp, TS Stanton, TC Warren, PA Cornett, FF Chehab. .
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    56. Characterization of a spontaneous mutation in beta-thalassemia associated with advanced paternal age. Blood. 1989 Aug 1; 74(2):852-854. FF Chehab, KH Winterhalter, YW Kan. .
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    57. Characterization of a spontaneous mutation in beta-thalassemia associated with advanced paternal age. Blood. 1989 Aug 01; 74(2):852-4. Chehab FF, Winterhalter KH, Kan YW. PMID: 2665856.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    58. Human placental Na+,K+-ATPase alpha subunit: cDNA cloning, tissue expression, DNA polymorphism, and chromosomal localization. Proc Natl Acad Sci U S A. 1987 Nov; 84(22):7901-5. Chehab FF, Kan YW, Law ML, Hartz J, Kao FT, Blostein R. PMID: 2891135.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    59. The molecular basis of beta-thalassemia in Lebanon: application to prenatal diagnosis. Blood. 1987 Apr 1; 69(4):1141-1145. FF Chehab, V Der Kaloustian, FP Khouri, SS Deeb, YW Kan. .
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