Hayarpi Torosyan

Title(s)Postdoctoral Scholar, Cardiovascular Research Inst
SchoolSchool of Medicine
AddressSan Francisco CA 94158
Phone415-514-4289
PronounsShe/Her/Hers
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Structural insights into regulation of the PEAK3 pseudokinase scaffold by 14-3-3. Nat Commun. 2023 06 19; 14(1):3543. Torosyan H, Paul MD, Forget A, Lo M, Diwanji D, Pawlowski K, Krogan NJ, Jura N, Verba KA. PMID: 37336883; PMCID: PMC10279700.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    2. CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids. Nat Commun. 2022 05 03; 13(1):2407. Lo M, Sharir A, Paul MD, Torosyan H, Agnew C, Li A, Neben C, Marangoni P, Xu L, Raleigh DR, Jura N, Klein OD. PMID: 35504891; PMCID: PMC9065090.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    3. Piquing our interest: Insights into the role of PEAK3 in signaling and disease. Sci Signal. 2022 02 22; 15(722):eabm9396. Paul MD, Torosyan H, Jura N. PMID: 35192418; PMCID: PMC9288111.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    4. Therapeutic implications of activating noncanonical PIK3CA mutations in head and neck squamous cell carcinoma. J Clin Invest. 2021 11 15; 131(22). Jin N, Keam B, Cho J, Lee MJ, Kim HR, Torosyan H, Jura N, Ng PK, Mills GB, Li H, Zeng Y, Barbash Z, Tarcic G, Kang H, Bauman JE, Kim MO, VanLandingham NK, Swaney DL, Krogan NJ, Johnson DE, Grandis JR. PMID: 34779417; PMCID: PMC8592538.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    5. Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding. ACS Chem Biol. 2020 08 21; 15(8):2137-2153. Newberry RW, Arhar T, Costello J, Hartoularos GC, Maxwell AM, Naing ZZC, Pittman M, Reddy NR, Schwarz DMC, Wassarman DR, Wu TS, Barrero D, Caggiano C, Catching A, Cavazos TB, Estes LS, Faust B, Fink EA, Goldman MA, Gomez YK, Gordon MG, Gunsalus LM, Hoppe N, Jaime-Garza M, Johnson MC, Jones MG, Kung AF, Lopez KE, Lumpe J, Martyn C, McCarthy EE, Miller-Vedam LE, Navarro EJ, Palar A, Pellegrino J, Saylor W, Stephens CA, Strickland J, Torosyan H, Wankowicz SA, Wong DR, Wong G, Redding S, Chow ED, DeGrado WF, Kampmann M. PMID: 32786289; PMCID: PMC7442712.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    6. The activities of drug inactive ingredients on biological targets. Science. 2020 07 24; 369(6502):403-413. Pottel J, Armstrong D, Zou L, Fekete A, Huang XP, Torosyan H, Bednarczyk D, Whitebread S, Bhhatarai B, Liang G, Jin H, Ghaemi SN, Slocum S, Lukacs KV, Irwin JJ, Berg EL, Giacomini KM, Roth BL, Shoichet BK, Urban L. PMID: 32703874; PMCID: PMC7960226.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    7. Protein Stability Effects in Aggregate-Based Enzyme Inhibition. J Med Chem. 2019 11 14; 62(21):9593-9599. Torosyan H, Shoichet BK. PMID: 31589047; PMCID: PMC7156261.
      View in: PubMed   Mentions: 11     Fields:    
    8. Triggered Release Enhances the Cytotoxicity of Stable Colloidal Drug Aggregates. ACS Chem Biol. 2019 07 19; 14(7):1507-1514. Donders EN, Ganesh AN, Torosyan H, Lak P, Shoichet BK, Shoichet MS. PMID: 31243955; PMCID: PMC7136197.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    9. Structure-based discovery of selective positive allosteric modulators of antagonists for the M2 muscarinic acetylcholine receptor. Proc Natl Acad Sci U S A. 2018 03 06; 115(10):E2419-E2428. Korczynska M, Clark MJ, Valant C, Xu J, Moo EV, Albold S, Weiss DR, Torosyan H, Huang W, Kruse AC, Lyda BR, May LT, Baltos JA, Sexton PM, Kobilka BK, Christopoulos A, Shoichet BK, Sunahara RK. PMID: 29453275; PMCID: PMC5877965.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    10. Internal Structure and Preferential Protein Binding of Colloidal Aggregates. ACS Chem Biol. 2017 01 20; 12(1):282-290. Duan D, Torosyan H, Elnatan D, McLaughlin CK, Logie J, Shoichet MS, Agard DA, Shoichet BK. PMID: 27983786; PMCID: PMC5491102.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    11. Structure-based approach for identification of novel phenylboronic acids as serine-β-lactamase inhibitors. J Comput Aided Mol Des. 2016 10; 30(10):851-861. Sgrignani J, De Luca F, Torosyan H, Docquier JD, Duan D, Novati B, Prati F, Colombo G, Grazioso G. PMID: 27632226.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    12. Identification of Novel Smoothened Ligands Using Structure-Based Docking. PLoS One. 2016; 11(8):e0160365. Lacroix C, Fish I, Torosyan H, Parathaman P, Irwin JJ, Shoichet BK, Angers S. PMID: 27490099; PMCID: PMC4973902.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    13. Stable Colloidal Drug Aggregates Catch and Release Active Enzymes. ACS Chem Biol. 2016 Apr 15; 11(4):992-1000. McLaughlin CK, Duan D, Ganesh AN, Torosyan H, Shoichet BK, Shoichet MS. PMID: 26741163; PMCID: PMC5082698.
      View in: PubMed   Mentions: 22     Fields:    
    14. An Aggregation Advisor for Ligand Discovery. J Med Chem. 2015 Sep 10; 58(17):7076-87. Irwin JJ, Duan D, Torosyan H, Doak AK, Ziebart KT, Sterling T, Tumanian G, Shoichet BK. PMID: 26295373; PMCID: PMC4646424.
      View in: PubMed   Mentions: 160     Fields:    
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