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Tumor heterogeneity underlies clinical outcome and MEK inhibitor response in somatic NF1-mutant glioblastoma. JCI Insight. 2025 Sep 23; 10(18).
Pan S, Mirchia K, Payne E, Liu SJ, Al-Adli N, Peeran Z, Shukla P, Young JS, Gupta R, Wu J, Pak J, Ozawa T, Na B, Reddy AT, Braunstein SE, Phillips JJ, Chang S, Solomon DA, Perry A, Raleigh DR, Berger MS, Abate AR, Vasudevan HN. PMID: 40985888.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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NOTCH3 drives fatty acid oxidation and ferroptosis resistance in aggressive meningiomas. J Neurooncol. 2025 Sep 09.
Sadagopan NS, Gomez M, Tripathi S, Billingham LK, DeLay SL, Cady MA, Congivaram HTS, Chia TY, Wan H, Wang S, Raleigh DR, Kaluba FC, Lien EC, Heimberger AB, Lee-Chang C, Youngblood MW, Magill ST, Miska JM. PMID: 40924320.
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PubMed Mentions: Fields:
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Proton Craniospinal Irradiation for Leptomeningeal Metastases. JAMA Oncol. 2025 Sep 04.
Boreta L, Raleigh DR. PMID: 40906467.
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PubMed Mentions: Fields:
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Preoperative embolization improves local control and modulates gene expression in atypical WHO grade 2 meningioma. Neuro Oncol. 2025 Sep 02.
Haddad AF, Ramesh R, Zakimi N, Chen JS, Quintana D, Gil E, Kabir AS, Sibih YE, Lugo BM, Bhalla S, Chen WC, Villanueva-Meyer JE, Narsinh KH, Magill ST, Morshed RA, Winkler E, Theodosopoulos PV, McDermott MW, Aghi MK, Raleigh DR. PMID: 40916651.
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PubMed Mentions: Fields:
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The effect of TERT promoter mutation on predicting meningioma outcomes: a multi-institutional cohort analysis. Lancet Oncol. 2025 Sep; 26(9):1178-1190.
Groff KJ, Patel RV, Feng Y, Ghosh HS, Millares Chavez MA, O'Brien J, Chen WC, Nitturi V, Save AV, Youngblood MW, Horbinski CM, Chandler JP, Ehret F, Gui C, Wang JZ, Park K, Ajmera S, Rosenblum M, Suwala AK, Kresbach C, Mount CW, Schüller U, Santagata S, Sahm F, Bale TA, Jackson C, Richardson TE, Cai C, Nassiri F, Zadeh G, Kaul D, Capper D, Magill ST, Golfinos JG, Sen C, Patel AJ, Raleigh DR, Moliterno J, Pacione D, Snuderl M, Bi WL. PMID: 40907515.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiation Therapy. Cancer Res. 2025 Jul 25.
Richman CM, Rasnitsyn A, Holgado BL, Vladoiu M, Abeysundara N, Majo S, Chabi S, Taunay LJ, Suzuki H, Shibahara I, Haapasalo J, Pallotta JG, Douglas T, Kharas K, Juraschka K, Ocsenas O, Kumar SA, Nordfors K, Guerreiro Stücklin A, Suarez RA, Zhang J, Wu X, Daniels C, Garzia L, Reimand J, Saulnier O, Merchant TE, Pouponnot C, Raleigh DR, Taylor MD, De Antonellis P. PMID: 40712054; PMCID: PMC12442109.
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PubMed Mentions: Fields:
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Cell atlas of the developing human meninges reveals a dura origin of meningioma. bioRxiv. 2025 Jul 13.
Vinsland E, Salas SM, Kapustová I, Hu L, Webb S, Li X, He X, Nilsson M, Haniffa M, Barker R, Persson O, Raleigh DR, Sundström E, Lönnerberg P, Linnarsson S. PMID: 40672210; PMCID: PMC12265625.
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PubMed Mentions:
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Pan-cancer copy number analysis identifies optimized size thresholds and co-occurrence models for individualized risk stratification. Nat Commun. 2025 Jul 02; 16(1):6024.
Nguyen MP, Chen WC, Mirchia K, Choudhury A, Zakimi N, Nitturi V, Klisch TJ, Magill ST, Lucas CG, Patel AJ, Raleigh DR. PMID: 40603285; PMCID: PMC12222647.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Therapeutic radiation drives leptomeningeal dissemination of medulloblastoma through an innate immune process. Dev Cell. 2025 Jun 26.
Nör C, Kharas K, Rasnitsyn A, Vladoiu MC, Cho NW, Young JS, Nör F, Mankahla N, Haapasalo J, Nordfors K, Rapic S, Skowron P, Suárez RA, Bahcheli AT, Ocsenas O, Chen X, Bahrampour S, Momin A, Sundaresan L, Ong W, Hendrikse LD, Abeysundara N, Juraschka K, Ly M, Pallota JG, Douglas T, Huang N, Wang H, Mak E, Qin L, Liu J, Shen L, Luu B, Manno A, Kumar SA, Donovan LK, Fong V, Richman C, Daniels C, Garzia L, Rich JN, Hawkins C, Wu X, DaCosta R, Reimand J, Huang X, Ramaswamy V, Raleigh DR, Taylor MD. PMID: 40609543.
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PubMed Mentions: Fields:
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NOTCH3 Drives Fatty Acid Oxidation and Ferroptosis Resistance in Aggressive Meningiomas. Res Sq. 2025 Jun 04.
Sadagopan NS, Gomez M, Tripathi S, Billingham LK, DeLay SL, Cady MA, Congivaram HTS, Chia TY, Wan H, Wang S, Raleigh DR, Kaluba FC, Lien EC, Heimberger AB, Lee-Chang C, Youngblood MW, Magill ST, Miska JM. PMID: 40502769; PMCID: PMC12155216.
View in:
PubMed Mentions:
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Author Correction: Multi-institutional atlas of brain metastases informs spatial modeling for precision imaging and personalized therapy. Nat Commun. 2025 Jun 02; 16(1):5096.
Barrios J, Porter E, Capaldi DPI, Upadhaya T, Chen WC, Perks JR, Apte A, Aristophanous M, LoCastro E, Hsu D, Stone PH, Villanueva-Meyer JE, Valdes G, Jiang F, Maddalena M, Ballangrud A, Prezelski K, Lin H, Sun JY, Aldin MAK, Chau OW, Ziemer B, Seaberg M, Sneed PK, Nakamura JL, Boreta LC, Fogh SE, Raleigh DR, Chew J, Vasudevan H, Cha S, Hess C, Fragoso R, Shultz DB, Pike L, Hervey-Jumper SL, Tsang DS, Theodosopoulos P, Cooke D, Benedict SH, Sheng K, Seuntjens J, Coolens C, Deasy JO, Braunstein S, Morin O. PMID: 40456774; PMCID: PMC12130313.
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PubMed Mentions: Fields:
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Aperiodic neural dynamics define a novel signature of glioma-induced excitation-inhibition dysregulation. bioRxiv. 2025 May 24.
Sibih YE, Dada AO, Cunningham E, Olshausen N, Kaur J, Jayabal V, Oten S, Herr S, Gonzales CN, Daniel A, Krishna S, Ambati VS, Aabedi AA, Umbach G, Mirchia K, Lalwani P, Chang EF, Raleigh DR, Nagarajan S, Brang D, Hervey-Jumper SL. PMID: 40475422; PMCID: PMC12139770.
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PubMed Mentions:
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Glioma-neuronal circuit remodeling induces regional immunosuppression. Nat Commun. 2025 May 22; 16(1):4770.
Nejo T, Krishna S, Yamamichi A, Lakshmanachetty S, Jimenez C, Lee KY, Baker DL, Young JS, Chen T, Phyu SSS, Phung L, Gallus M, Maldonado GC, Okada K, Ogino H, Watchmaker PB, Diebold D, Choudhury A, Daniel AGS, Cadwell CR, Raleigh DR, Hervey-Jumper SL, Okada H. PMID: 40404658; PMCID: PMC12098748.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Genomic features underlying meningioma sex-specificity. Neuro Oncol. 2025 May 15; 27(4):1029-1030.
Raleigh DR. PMID: 39776156; PMCID: PMC12083219.
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PubMed Mentions: Fields:
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Multi-institutional atlas of brain metastases informs spatial modeling for precision imaging and personalized therapy. Nat Commun. 2025 May 15; 16(1):4536.
Barrios J, Porter E, Capaldi DPI, Upadhaya T, Chen WC, Perks JR, Apte A, Aristophanous M, LoCastro E, Hsu D, Stone PH, Villanueva-Meyer JE, Valdes G, Jiang F, Maddalena M, Ballangrud A, Prezelski K, Lin H, Sun JY, Aldin MAK, Chau OW, Ziemer B, Seaberg M, Sneed PK, Nakamura JL, Boreta LC, Fogh SE, Raleigh DR, Chew J, Vasudevan H, Cha S, Hess C, Fragoso R, Shultz DB, Pike L, Hervey-Jumper SL, Tsang DS, Theodosopoulos P, Cooke D, Benedict SH, Sheng K, Seuntjens J, Coolens C, Deasy JO, Braunstein S, Morin O. PMID: 40374598; PMCID: PMC12081687.
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PubMed Mentions: Fields:
Translation:
Humans
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European Association of Neuro-Oncology guideline on molecular testing of meningiomas for targeted therapy selection. Neuro Oncol. 2025 May 15; 27(4):869-883.
Sahm F, Bertero L, Brandner S, Capper D, Goldbrunner R, Jenkinson MD, Kalamarides M, Lamszus K, Albert NL, Mair MJ, Berghoff AS, Mawrin C, Wirsching HG, Maas SLN, Raleigh DR, Reifenberger G, Schweizer L, Suwala AK, Tabatabai G, Tabouret E, Short S, Wen PY, Weller M, Le Rhun E, Wesseling P, van den Bent M, Preusser M. PMID: 39577862; PMCID: PMC12083233.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Genomic Alterations Have Prognostic Significance in Low Clinical Risk Meningiomas. World Neurosurg. 2025 Aug; 200:124085.
Morshed RA, Raleigh DR. PMID: 40472706.
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PubMed Mentions: Fields:
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Spatial synaptic connectivity underlies oligodendroglioma evolution and recurrence. Res Sq. 2025 Apr 04.
Raleigh D, Mirchia K, Oten S, Picart T, Nguyen M, Ambati V, Vasudevan H, Young J, Taylor J, Krishna S, Brang D, Phillips J, Perry A, Berger M, Chang S, de Groot J, Hervey-Jumper S. PMID: 40235496; PMCID: PMC11998797.
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PubMed Mentions:
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IL-6 underlies microenvironment immunosuppression and resistance to therapy in glioblastoma. bioRxiv. 2025 Mar 14.
Young JS, Cho NW, Lucas CG, Najem H, Mirchia K, Chen WC, Seo K, Zakimi N, Daggubati V, Casey-Clyde T, Nguyen MP, Chen A, Phillips JJ, Ozawa T, Aghi MK, Taylor JW, DeRisi JL, Bhaduri A, Berger MS, Heimberger AB, Butowski N, Spitzer MH, Raleigh DR. PMID: 40161763; PMCID: PMC11952432.
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PubMed Mentions:
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Multiplexed epigenetic memory editing using CRISPRoff sensitizes glioblastoma to chemotherapy. Neuro Oncol. 2025 Feb 25.
Lin K, Zou C, Hubbard A, Sengelmann S, Goudy L, Wang IC, Sharma R, Pak J, Foster K, Ozawa T, de Groot JF, Phillips J, Vasudevan HN, Raleigh DR, Marson A, Murthy N, Gilbert LA, Berger MS, Liu SJ. PMID: 39998382.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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A targeted gene expression biomarker predicts clinic low-risk meningioma recurrence. Neuro Oncol. 2025 Feb 10; 27(2):445-454.
Nguyen MP, Morshed RA, Youngblood MW, Perlow HK, Lucas CG, Patel AJ, Palmer JD, Horbinski CM, Magill ST, Chen WC, Raleigh DR. PMID: 39340366; PMCID: PMC11812033.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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cIMPACT-NOW update 8: Clarifications on molecular risk parameters and recommendations for WHO grading of meningiomas. Neuro Oncol. 2025 Feb 10; 27(2):319-330.
Sahm F, Aldape KD, Brastianos PK, Brat DJ, Dahiya S, von Deimling A, Giannini C, Gilbert MR, Louis DN, Raleigh DR, Reifenberger G, Santagata S, Sarkar C, Zadeh G, Wesseling P, Perry A. PMID: 39212325; PMCID: PMC11812049.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Grade-stratified meningioma risk among individuals who are non-Hispanic Black and interactions with male sex. J Natl Cancer Inst. 2025 Feb 01; 117(2):366-374.
Walsh KM, Price M, Raleigh DR, Calabrese E, Kruchko C, Barnholtz-Sloan JS, Ostrom QT. PMID: 39392420; PMCID: PMC11807431.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Meningeal solitary fibrous tumor cell states phenocopy cerebral vascular development and homeostasis. Neuro Oncol. 2025 Jan 12; 27(1):155-166.
Mirchia K, Choudhury A, Joseph T, Birrueta JO, Phillips JJ, Bhaduri A, Crouch EE, Perry A, Raleigh DR. PMID: 39207122; PMCID: PMC11726342.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Longitudinal multimodal profiling of IDH-wildtype glioblastoma reveals the molecular evolution and cellular phenotypes underlying prognostically different treatment responses. Neuro Oncol. 2025 Jan 12; 27(1):89-105.
Lucas CG, Al-Adli NN, Young JS, Gupta R, Morshed RA, Wu J, Ravindranathan A, Shai A, Oberheim Bush NA, Taylor JW, de Groot J, Villanueva-Meyer JE, Pekmezci M, Perry A, Bollen AW, Theodosopoulos PV, Aghi MK, Chang EF, Hervey-Jumper SL, Raleigh DR, Molinaro AM, Costello JF, Diaz AA, Clarke JL, Butowski NA, Phillips JJ, Chang SM, Berger MS, Solomon DA. PMID: 39560080; PMCID: PMC11726253.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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The Impact of MRI-Defined Extent of Resection Across Meningioma DNA Methylation Groups: Re-Evaluating Surgery in the Era of Meningioma Molecular Classification. Neurosurgery. 2025 Jan 07.
Morshed RA, Nguyen MP, Choudhury A, Al-Adli NN, Magill ST, Haddad AF, Mirchia K, Lucas CG, Theodosopoulos PV, McDermott MW, Chen WC, Raleigh DR. PMID: 39773932.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Molecular evolution of metastatic meningioma: A case report. Clin Neuropathol. 2025 Jan-Feb; 44(1):9-15.
Kahr J, Stein KP, John P, Walles T, Roepke M, Neyazi B, Sandalcioglu IE, Raleigh DR, Mawrin C. PMID: 39969396.
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PubMed Mentions: Fields:
Translation:
Humans
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A generative framework for enhanced cell-type specificity in rationally designed mRNAs. bioRxiv. 2024 Dec 31.
Khoroshkin M, Zinkevich A, Aristova E, Yousefi H, Lee SB, Mittmann T, Manegold K, Penzar D, Raleigh DR, Kulakovskiy IV, Goodarzi H. PMID: 39803435; PMCID: PMC11722239.
View in:
PubMed Mentions:
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Consensus Radiation Treatment Planning Guidelines Using (68)Ga-DOTATATE PET/CT For Resected Meningiomas. Int J Radiat Oncol Biol Phys. 2025 May 01; 122(1):150-158.
Perlow HK, Raleigh DR, Wang TJC, Pollom EL, Milano MT, Breen WG, Detsky J, Chang EL, Tom MC, Shiue KR, Lehrer EJ, Saeed H, Pike LRG, Lo SS, Mishra MV, Knisely JPS, Chao ST, Sahgal A, Palmer JD. PMID: 39701546.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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RNA splicing as a biomarker and phenotypic driver of meningioma DNA-methylation groups. Neuro Oncol. 2024 Dec 05; 26(12):2222-2236.
Leclair NK, Choudury A, Chen WC, Magill ST, McCortney K, Horbinski CM, Chen Z, Goldschmidt E, Eaton CD, Bulsara KR, Bi WL, Patel AJ, Sahm F, Raleigh D, Anczukow O. PMID: 39093629; PMCID: PMC11630566.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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High-Grade Progression, Sarcomatous Transformation, and/or Metastasis of Pituitary Neuroendocrine Neoplasms (PitNENs): The UCSF Experience. Endocr Pathol. 2024 Dec; 35(4):338-348.
Terry M, Nguyen MP, Tang V, Guney E, Bharani KL, Dahiya S, Choutka O, Borys E, Reis G, Blevins L, Aghi MK, Kunwar S, DeGroot J, Raleigh DR, Pekmezci M, Bollen AW, Cha S, Joseph NM, Perry A. PMID: 39388031; PMCID: PMC11659330.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma. Genome Biol. 2024 Oct 07; 25(1):256.
Liu SJ, Zou C, Pak J, Morse A, Pang D, Casey-Clyde T, Borah AA, Wu D, Seo K, O'Loughlin T, Lim DA, Ozawa T, Berger MS, Kamber RA, Weiss WA, Raleigh DR, Gilbert LA. PMID: 39375777; PMCID: PMC11457336.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Perivascular NOTCH3+ Stem Cells Drive Meningioma Tumorigenesis and Resistance to Radiotherapy. Cancer Discov. 2024 Oct 04; 14(10):1823-1837.
Choudhury A, Cady MA, Lucas CG, Najem H, Phillips JJ, Palikuqi B, Zakimi N, Joseph T, Birrueta JO, Chen WC, Oberheim Bush NA, Hervey-Jumper SL, Klein OD, Toedebusch CM, Horbinski CM, Magill ST, Bhaduri A, Perry A, Dickinson PJ, Heimberger AB, Ashworth A, Crouch EE, Raleigh DR. PMID: 38742767; PMCID: PMC11452293.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Meningioma: International Consortium on Meningiomas consensus review on scientific advances and treatment paradigms for clinicians, researchers, and patients. Neuro Oncol. 2024 Oct 03; 26(10):1742-1780.
Wang JZ, Landry AP, Raleigh DR, Sahm F, Walsh KM, Goldbrunner R, Yefet LS, Tonn JC, Gui C, Ostrom QT, Barnholtz-Sloan J, Perry A, Ellenbogen Y, Hanemann CO, Jungwirth G, Jenkinson MD, Tabatabai G, Mathiesen TI, McDermott MW, Tatagiba M, la Fougère C, Maas SLN, Galldiks N, Albert NL, Brastianos PK, Ehret F, Minniti G, Lamszus K, Ricklefs FL, Schittenhelm J, Drummond KJ, Dunn IF, Pathmanaban ON, Cohen-Gadol AA, Sulman EP, Tabouret E, Le Rhun E, Mawrin C, Moliterno J, Weller M, Bi WL, Gao A, Yip S, Niyazi M, International Consortium on Meningiomas (ICOM), Aldape K, Wen PY, Short S, Preusser M, Nassiri F, Zadeh G. PMID: 38695575; PMCID: PMC11449035.
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PubMed Mentions:
35 Fields:
Translation:
Humans
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MerlinS13 phosphorylation regulates meningioma Wnt signaling and magnetic resonance imaging features. Nat Commun. 2024 09 09; 15(1):7873.
Eaton CD, Avalos L, Liu SJ, Chen Z, Zakimi N, Casey-Clyde T, Bisignano P, Lucas CG, Stevenson E, Choudhury A, Vasudevan HN, Magill ST, Young JS, Krogan NJ, Villanueva-Meyer JE, Swaney DL, Raleigh DR. PMID: 39251601; PMCID: PMC11383945.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Proteasome inhibition for glioblastoma: Lessons learned and new opportunities. Neuro Oncol. 2024 Sep 05; 26(9):1683-1684.
Liu SJ, Raleigh DR, de Groot JF. PMID: 38934653; PMCID: PMC11376452.
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PubMed Mentions: Fields:
Translation:
Humans
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The RNA-binding protein IGF2BP1 regulates stability of mRNA transcribed from FOXM1 target genes in hypermitotic meningiomas. Acta Neuropathol. 2024 Aug 23; 148(1):28.
Leclair NK, Lucas CG, Mirchia K, McCortney K, Horbinski CM, Raleigh DR, Anczukow O. PMID: 39179895; PMCID: PMC11343784.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Gene Expression Changes Associated With Recurrence After Gross Total Resection of Newly Diagnosed World Health Organization Grade 1 Meningioma. Neurosurgery. 2025 Mar 01; 96(3):521-528.
Morshed RA, Nguyen MP, Youngblood MW, Perlow HK, Lucas CG, Patel AJ, Palmer JD, Chandler JP, Theodosopoulos PV, Magill ST, Chen WC, Raleigh DR. PMID: 39101743.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
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Cilia-enriched oxysterol 7β,27-DHC is required for polycystin ion channel activation. Nat Commun. 2024 Jul 31; 15(1):6468.
Ha K, Mundt-Machado N, Bisignano P, Pinedo A, Raleigh DR, Loeb G, Reiter JF, Cao E, Delling M. PMID: 39085216; PMCID: PMC11291729.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Glioblastoma Neurovascular Progenitor Orchestrates Tumor Cell Type Diversity. bioRxiv. 2024 Jul 24.
Fazzari E, Azizad DJ, Yu K, Ge W, Li MX, Nano PR, Kan RL, Tum HA, Tse C, Bayley NA, Haka V, Cadet D, Perryman T, Soto JA, Wick B, Raleigh DR, Crouch EE, Patel KS, Liau LM, Deneen B, Nathanson DA, Bhaduri A. PMID: 39091877; PMCID: PMC11291138.
View in:
PubMed Mentions:
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Eed controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crest. bioRxiv. 2024 Jul 12.
Casey-Clyde T, Liu SJ, Serrano JAC, Teng C, Jang YG, Vasudevan HN, Bush JO, Raleigh DR. PMID: 38558995; PMCID: PMC10979956.
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PubMed Mentions:
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Correction to: Leveraging single-cell sequencing to classify and characterize tumor subgroups in bulk RNA-sequencing data. J Neurooncol. 2024 Jul; 168(3):525.
Shetty A, Wang S, Khan AB, English CW, Nouri SH, Magill ST, Raleigh DR, Klisch TJ, Harmanci AO, Patel AJ, Harmanci AS. PMID: 38834749.
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PubMed Mentions: Fields:
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Calcified Meningiomas Demonstrate Equivocal Grade, Proliferation, and Immediate Surgical Outcomes. World Neurosurg. 2024 09; 189:e591-e597.
Umbach G, Kanungo I, Quintana D, Choudhury A, Morshed R, Villanueva-Meyer J, Theodosopoulos P, Magill ST, McDermott M, Raleigh D, Goldschmidt E. PMID: 38936608.
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PubMed Mentions: Fields:
Translation:
Humans
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Elevated meningioma risk among individuals who are Non-Hispanic Black is strongest for grade 2-3 tumors and synergistically modified by male sex. medRxiv. 2024 Jun 13.
Walsh KM, Price M, Raleigh DR, Calabrese E, Kruchko C, Barnholtz-Sloan JS, Ostrom QT. PMID: 38947051; PMCID: PMC11213081.
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PubMed Mentions:
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Response to immune checkpoint inhibition in a meningioma with DNA mismatch repair deficiency. Neurooncol Adv. 2024 Jan-Dec; 6(1):vdae092.
Nguyen MP, Almiron Bonnin D, Mirchia K, Chen WC, Goldschmidt E, Braunstein SE, Perry A, Raleigh DR, Oberheim Bush NA. PMID: 38957162; PMCID: PMC11217898.
View in:
PubMed Mentions:
1
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Leveraging single-cell sequencing to classify and characterize tumor subgroups in bulk RNA-sequencing data. J Neurooncol. 2024 Jul; 168(3):515-524.
Shetty A, Wang S, Khan AB, English CW, Nouri SH, Magill ST, Raleigh DR, Klisch TJ, Harmanci AO, Patel AJ, Harmanci AS. PMID: 38811523.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Meningioma transcriptomic landscape demonstrates novel subtypes with regional associated biology and patient outcome. Cell Genom. 2024 Jun 12; 4(6):100566.
Thirimanne HN, Almiron-Bonnin D, Nuechterlein N, Arora S, Jensen M, Parada CA, Qiu C, Szulzewsky F, English CW, Chen WC, Sievers P, Nassiri F, Wang JZ, Klisch TJ, Aldape KD, Patel AJ, Cimino PJ, Zadeh G, Sahm F, Raleigh DR, Shendure J, Ferreira M, Holland EC. PMID: 38788713; PMCID: PMC11228955.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Spatial genomic, biochemical and cellular mechanisms underlying meningioma heterogeneity and evolution. Nat Genet. 2024 Jun; 56(6):1121-1133.
Lucas CG, Mirchia K, Seo K, Najem H, Chen WC, Zakimi N, Foster K, Eaton CD, Cady MA, Choudhury A, Liu SJ, Phillips JJ, Magill ST, Horbinski CM, Solomon DA, Perry A, Vasudevan HN, Heimberger AB, Raleigh DR. PMID: 38760638; PMCID: PMC11239374.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Implications and interchangeability of meningioma biomarkers for clinical trials and clinical practice. J Neurooncol. 2024 Aug; 169(1):215-217.
Raleigh DR, Chen WC, Gondi V, Rogers L, Mehta M. PMID: 38743346.
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PubMed Mentions: Fields:
Translation:
Humans
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Radiotherapy dose escalation for high-risk meningiomas after subtotal resection. Neuro Oncol. 2024 04 05; 26(4):713-714.
Raleigh DR. PMID: 38153397; PMCID: PMC10995498.
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PubMed Mentions: Fields:
Translation:
Humans
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NAB2::STAT6 fusions and genome-wide DNA methylation profiling: Predictors of patient outcomes in meningeal solitary fibrous tumors. Brain Pathol. 2024 Nov; 34(6):e13256.
Eschbacher KL, Tran QT, Moskalev EA, Jenkins S, Fritchie K, Stoehr R, Caron A, Link MJ, Brown PD, Guajardo A, Brat DJ, Wu A, Santagata S, Louis DN, Brastianos PK, Kaplan AB, Alexander B, Rossi S, Ferrarese F, Raleigh DR, Nguyen MP, Gross J, Velazquez Vega J, Rodriguez F, Perry A, Martinez-Lage M, Orr BA, Haller F, Giannini C. PMID: 38523251; PMCID: PMC11483515.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Gene transcript fusions are associated with clinical outcomes and molecular groups of meningiomas. Acta Neuropathol. 2024 03 20; 147(1):57.
Zakimi N, Nguyen MP, Raleigh DR. PMID: 38509407; PMCID: PMC10954959.
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PubMed Mentions: Fields:
Translation:
Humans
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Canine meningiomas are comprised of 3 DNA methylation groups that resemble the molecular characteristics of human meningiomas. Acta Neuropathol. 2024 02 20; 147(1):43.
Zakimi N, Mazcko CN, Toedebusch C, Tawa G, Woolard K, LeBlanc AK, Dickinson PJ, Raleigh DR. PMID: 38376604; PMCID: PMC10879255.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Adverse radiation effect versus tumor progression following stereotactic radiosurgery for brain metastases: Implications of radiologic uncertainty. J Neurooncol. 2024 Feb; 166(3):535-546.
Salans M, Ni L, Morin O, Ziemer B, Capaldi DPI, Raleigh DR, Vasudevan HN, Chew J, Nakamura J, Sneed PK, Boreta L, Villanueva-Meyer JE, Theodosopoulos P, Braunstein S. PMID: 38316705; PMCID: PMC10876820.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansPHPublic Health
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A 34-gene expression biomarker predicts meningioma outcomes and radiotherapy responses. Neuro Oncol. 2024 02 02; 26(2):207-208.
Raleigh DR, Preusser M. PMID: 37963810; PMCID: PMC10836762.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Functional interactions between neurofibromatosis tumor suppressors underlie Schwann cell tumor de-differentiation and treatment resistance. Nat Commun. 2024 Jan 12; 15(1):477.
Vasudevan HN, Payne E, Delley CL, John Liu S, Mirchia K, Sale MJ, Lastella S, Nunez MS, Lucas CG, Eaton CD, Casey-Clyde T, Magill ST, Chen WC, Braunstein SE, Perry A, Jacques L, Reddy AT, Pekmezci M, Abate AR, McCormick F, Raleigh DR. PMID: 38216572; PMCID: PMC10786885.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Epigenetic reprogramming shapes the cellular landscape of schwannoma. Nat Commun. 2024 Jan 12; 15(1):476.
Liu SJ, Casey-Clyde T, Cho NW, Swinderman J, Pekmezci M, Dougherty MC, Foster K, Chen WC, Villanueva-Meyer JE, Swaney DL, Vasudevan HN, Choudhury A, Pak J, Breshears JD, Lang UE, Eaton CD, Hiam-Galvez KJ, Stevenson E, Chen KH, Lien BV, Wu D, Braunstein SE, Sneed PK, Magill ST, Lim D, McDermott MW, Berger MS, Perry A, Krogan NJ, Hansen MR, Spitzer MH, Gilbert L, Theodosopoulos PV, Raleigh DR. PMID: 38216587; PMCID: PMC10786948.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
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Pan-cancer copy number variant analysis identifies optimized size thresholds and co-occurrence models for individualized risk-stratification. Res Sq. 2024 Jan 11.
Raleigh D, Nguyen M, Chen W, Zakimi N, Mirchia K, Lucas CH. PMID: 38260689; PMCID: PMC10802684.
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PubMed Mentions:
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Epidemiology, Genetics, and DNA Methylation Grouping of Hyperostotic Meningiomas. Oper Neurosurg (Hagerstown). 2024 Jun 01; 26(6):662-668.
Umbach G, Tran EB, Eaton CD, Choudhury A, Morshed R, Villanueva-Meyer JE, Theodosopoulos PV, Magill ST, McDermott MW, Raleigh DR, Goldschmidt E. PMID: 38189372.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
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"De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade. Acta Neuropathol. 2023 12 11; 147(1):3.
Hadad S, Gupta R, Oberheim Bush NA, Taylor JW, Villanueva-Meyer JE, Young JS, Wu J, Ravindranathan A, Zhang Y, Warrier G, McCoy L, Shai A, Pekmezci M, Perry A, Bollen AW, Phillips JJ, Braunstein SE, Raleigh DR, Theodosopoulos P, Aghi MK, Chang EF, Hervey-Jumper SL, Costello JF, de Groot J, Butowski NA, Clarke JL, Chang SM, Berger MS, Molinaro AM, Solomon DA. PMID: 38079020; PMCID: PMC10713691.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
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Multiomic screening of invasive GBM cells reveals targetable transsulfuration pathway alterations. J Clin Invest. 2023 Nov 16; 134(3).
Garcia JH, Akins EA, Jain S, Wolf KJ, Zhang J, Choudhary N, Lad M, Shukla P, Rios J, Seo K, Gill SA, Carson WH, Carette LR, Zheng AC, Raleigh DR, Kumar S, Aghi MK. PMID: 37971886; PMCID: PMC10849762.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses. Nat Med. 2023 Dec; 29(12):3067-3076.
Chen WC, Choudhury A, Youngblood MW, Polley MC, Lucas CG, Mirchia K, Maas SLN, Suwala AK, Won M, Bayley JC, Harmanci AS, Harmanci AO, Klisch TJ, Nguyen MP, Vasudevan HN, McCortney K, Yu TJ, Bhave V, Lam TC, Pu JK, Li LF, Leung GK, Chan JW, Perlow HK, Palmer JD, Haberler C, Berghoff AS, Preusser M, Nicolaides TP, Mawrin C, Agnihotri S, Resnick A, Rood BR, Chew J, Young JS, Boreta L, Braunstein SE, Schulte J, Butowski N, Santagata S, Spetzler D, Bush NAO, Villanueva-Meyer JE, Chandler JP, Solomon DA, Rogers CL, Pugh SL, Mehta MP, Sneed PK, Berger MS, Horbinski CM, McDermott MW, Perry A, Bi WL, Patel AJ, Sahm F, Magill ST, Raleigh DR. PMID: 37944590; PMCID: PMC11073469.
View in:
PubMed Mentions:
43 Fields:
Translation:
Humans
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A Prospective Registry Study of 68Ga-DOTATATE PET/CT Incorporation Into Treatment Planning of Intracranial Meningiomas. Int J Radiat Oncol Biol Phys. 2024 Mar 15; 118(4):979-985.
Perlow HK, Nalin AP, Handley D, Gokun Y, Blakaj DM, Beyer SJ, Thomas EM, Raval RR, Boulter D, Kleefisch C, Bovi J, Chen WC, Braunstein SE, Raleigh DR, Knisely JPS, Ivanidze J, Palmer JD. PMID: 37871886.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
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Glioma-neuronal circuit remodeling induces regional immunosuppression. bioRxiv. 2023 Aug 06.
Nejo T, Krishna S, Jimenez C, Yamamichi A, Young JS, Lakshmanachetty S, Chen T, Phyu SSS, Ogino H, Watchmaker P, Diebold D, Choudhury A, Daniel AGS, Raleigh DR, Hervey-Jumper SL, Okada H. PMID: 37577659; PMCID: PMC10418167.
View in:
PubMed Mentions:
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Hedgehog target genes regulate lipid metabolism to drive basal cell carcinoma and medulloblastoma. Res Sq. 2023 Aug 03.
Daggubati V, Vykunta A, Choudhury A, Qadeer Z, Mirchia K, Saulnier O, Zakimi N, Hines K, Paul M, Wang L, Jura N, Xu L, Reiter J, Taylor M, Weiss W, Raleigh D. PMID: 37577529; PMCID: PMC10418546.
View in:
PubMed Mentions:
1
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Molecular Features of Resected Melanoma Brain Metastases, Clinical Outcomes, and Responses to Immunotherapy. JAMA Netw Open. 2023 08 01; 6(8):e2329186.
Vasudevan HN, Delley C, Chen WC, Mirchia K, Pan S, Shukla P, Aabedi AA, Nguyen MP, Morshed RA, Young JS, Boreta L, Fogh SE, Nakamura JL, Theodosopoulos PV, Phillips J, Hervey-Jumper SL, Daras M, Pike L, Aghi MK, Tsai K, Raleigh DR, Braunstein SE, Abate AR. PMID: 37589977; PMCID: PMC10436135.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Meningeal solitary fibrous tumor cell states phenocopy cerebral vascular development and homeostasis. Res Sq. 2023 Jul 26.
Raleigh D, Mirchia K, Choudhury A, Joseph T, Birrueta J, Phillips J, Bhaduri A, Crouch E, Perry A. PMID: 37546798; PMCID: PMC10402198.
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PubMed Mentions:
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NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy. bioRxiv. 2023 Jul 11.
Choudhury A, Cady MA, Lucas CG, Najem H, Phillips JJ, Palikuqi B, Zakimi N, Joseph T, Birrueta JO, Chen WC, Bush NAO, Hervey-Jumper SL, Klein OD, Toedebusch CM, Horbinski CM, Magill ST, Bhaduri A, Perry A, Dickinson PJ, Heimberger AB, Ashworth A, Crouch EE, Raleigh DR. PMID: 37503127; PMCID: PMC10369862.
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PubMed Mentions:
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Correction: Increased mRNA expression of CDKN2A is a transcriptomic marker of clinically aggressive meningiomas. Acta Neuropathol. 2023 Jul; 146(1):171-172.
Wang JZ, Patil V, Liu J, Dogan H, Tabatabai G, Yefet LS, Behling F, Hoffman E, Bunda S, Yakubov R, Kaloti R, Brandner S, Gao A, Cohen-Gadol A, Barnholtz-Sloan J, Skardelly M, Tatagiba M, Raleigh DR, Sahm F, Boutros PC, Aldape K, International Consortium on Meningiomas (ICOM), Nassiri F, Zadeh G. PMID: 37171636; PMCID: PMC10261159.
View in:
PubMed Mentions:
1 Fields:
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Post-Surgical Prognosis of Patients with Pineoblastoma: A Systematic Review and Individual Patient Data Analysis with Trends over Time. Cancers (Basel). 2023 Jun 27; 15(13).
Nandoliya KR, Sadagopan NS, Thirunavu V, Houskamp EJ, Karras CL, Chaliparambil RK, Sriram N, Jamshidi P, Raleigh DR, Lukas RV, Magill ST. PMID: 37444483; PMCID: PMC10340270.
View in:
PubMed Mentions:
3
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Radiotherapy and radiosurgery for meningiomas. Neurooncol Adv. 2023 May; 5(Suppl 1):i67-i83.
Chen WC, Lucas CG, Magill ST, Rogers CL, Raleigh DR. PMID: 37711972; PMCID: PMC10498143.
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PubMed Mentions:
14
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Spatial genomic, biochemical, and cellular mechanisms drive meningioma heterogeneity and evolution. Res Sq. 2023 May 15.
Lucas CH, Mirchia K, Seo K, Najem H, Chen W, Zakimi N, Choudhury A, Liu SJ, Phillips J, Magill S, Horbinski C, Solomon D, Perry A, Vasudevan H, Heimberger A, Raleigh D. PMID: 37292686; PMCID: PMC10246120.
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PubMed Mentions:
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Glioblastoma remodelling of human neural circuits decreases survival. Nature. 2023 05; 617(7961):599-607.
Krishna S, Choudhury A, Keough MB, Seo K, Ni L, Kakaizada S, Lee A, Aabedi A, Popova G, Lipkin B, Cao C, Nava Gonzales C, Sudharshan R, Egladyous A, Almeida N, Zhang Y, Molinaro AM, Venkatesh HS, Daniel AGS, Shamardani K, Hyer J, Chang EF, Findlay A, Phillips JJ, Nagarajan S, Raleigh DR, Brang D, Monje M, Hervey-Jumper SL. PMID: 37138086; PMCID: PMC10191851.
View in:
PubMed Mentions:
140 Fields:
Translation:
Humans
-
Increased mRNA expression of CDKN2A is a transcriptomic marker of clinically aggressive meningiomas. Acta Neuropathol. 2023 07; 146(1):145-162.
Wang JZ, Patil V, Liu J, Dogan H, Tabatabai G, Yefet LS, Behling F, Hoffman E, Bunda S, Yakubov R, Kaloti R, Brandner S, Gao A, Cohen-Gadol A, Barnholtz-Sloan J, Skardelly M, Tatagiba M, Raleigh DR, Sahm F, Boutros PC, Aldape K, International Consortium on Meningiomas (ICOM), Nassiri F, Zadeh G. PMID: 37093270; PMCID: PMC10261216.
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PubMed Mentions:
24 Fields:
Translation:
HumansCells
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Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses. Res Sq. 2023 Mar 20.
Raleigh D, Chen W, Choudhury A, Youngblood M, Polley MY, Lucas CH, Mirchia K, Maas S, Suwala A, Won M, Bayley J, Harmanci A, Harmanci A, Klisch T, Nguyen M, Vasudevan H, McCortney K, Yu T, Bhave V, Lam TC, Pu J, Leung G, Chang J, Perlow H, Palmer J, Haberler C, Berghoff A, Preusser M, Nicolaides T, Mawrin C, Agnihotri S, Resnick A, Rood B, Chew J, Young J, Boreta L, Braunstein S, Schulte J, Butowski N, Santagata S, Spetzler D, Bush NAO, Villanueva-Meyer J, Chandler J, Solomon D, Rogers C, Pugh S, Mehta M, Sneed P, Berger M, Horbinski C, McDermott M, Perry A, Bi W, Patel A, Sahm F, Magill S. PMID: 36993741; PMCID: PMC10055655.
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PubMed Mentions:
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MerlinS13 phosphorylation controls meningioma Wnt signaling and magnetic resonance imaging features. Res Sq. 2023 Mar 14.
Eaton C, Avalos L, Liu SJ, Casey-Clyde T, Bisignano P, Lucas CH, Stevenson E, Choudhury A, Vasudevan H, Magill S, Krogan N, Villanueva-Meyer J, Swaney D, Raleigh D. PMID: 36993679; PMCID: PMC10055685.
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PubMed Mentions:
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Hypermitotic meningiomas harbor DNA methylation subgroups with distinct biological and clinical features. Neuro Oncol. 2023 03 14; 25(3):520-530.
Choudhury A, Chen WC, Lucas CG, Bayley JC, Harmanci AS, Maas SLN, Santagata S, Klisch T, Perry A, Bi WL, Sahm F, Patel AJ, Magill ST, Raleigh DR. PMID: 36227281; PMCID: PMC10013643.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansCells
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Even heterozygous loss of CDKN2A/B greatly accelerates recurrence in aggressive meningioma. Acta Neuropathol. 2023 04; 145(4):501-503.
Khan AB, English CW, Chen WC, Athukuri P, Bayley JC, Brandt VL, Shetty A, Hadley CC, Choudhury A, Lu HC, Harmanci AO, Harmanci AS, Magill ST, Raleigh DR, Klisch TJ, Patel AJ. PMID: 36729132; PMCID: PMC10323927.
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PubMed Mentions:
19 Fields:
Translation:
Humans
-
Loss of p16 expression is a sensitive marker of CDKN2A homozygous deletion in malignant meningiomas. Acta Neuropathol. 2023 04; 145(4):497-500.
Tang V, Lu R, Mirchia K, Van Ziffle J, Devine P, Lee J, Phillips JJ, Perry A, Raleigh DR, Lucas CG, Solomon DA. PMID: 36723772; PMCID: PMC10020299.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
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Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling. J Clin Invest. 2023 01 17; 133(2).
Lee D, Gimple RC, Wu X, Prager BC, Qiu Z, Wu Q, Daggubati V, Mariappan A, Gopalakrishnan J, Sarkisian MR, Raleigh DR, Rich JN. PMID: 36394953; PMCID: PMC9843063.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
-
Radiotherapy for Meningioma. Adv Exp Med Biol. 2023; 1416:95-106.
Susko MS, Raleigh DR. PMID: 37432622.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
A single-cell atlas of glioblastoma evolution under therapy reveals cell-intrinsic and cell-extrinsic therapeutic targets. Nat Cancer. 2022 12; 3(12):1534-1552.
Wang L, Jung J, Babikir H, Shamardani K, Jain S, Feng X, Gupta N, Rosi S, Chang S, Raleigh D, Solomon D, Phillips JJ, Diaz AA. PMID: 36539501; PMCID: PMC9767870.
View in:
PubMed Mentions:
117 Fields:
Translation:
Humans
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Mutational Status and Clinical Outcomes Following Systemic Therapy with or without Focal Radiation for Resected Melanoma Brain Metastases. World Neurosurg. 2023 02; 170:e514-e519.
Vasudevan HN, Susko MS, Ma L, Nakamura JL, Raleigh DR, Boreta L, Fogh S, Theodosopoulos PV, McDermott MW, Tsai KK, Sneed PK, Braunstein SE. PMID: 36400359.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Radiotherapy for meningiomas. J Neurooncol. 2022 Nov; 160(2):505-515.
Chen WC, Perlow HK, Choudhury A, Nguyen MP, Mirchia K, Youngblood MW, Lucas CG, Palmer JD, Magill ST, Raleigh DR. PMID: 36315366; PMCID: PMC9722800.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
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A case (report) for mechanistic validation of meningioma molecular therapies. Neurooncol Adv. 2022 Jan-Dec; 4(1):vdac162.
Nguyen MP, Seo K, Eaton CD, Lucas CG, Chen WC, Choudhury A, Young JS, Raleigh DR. PMID: 36382111; PMCID: PMC9639353.
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PubMed Mentions:
2
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Gene expression analysis during progression of malignant meningioma compared to benign meningioma. J Neurosurg. 2023 05 01; 138(5):1302-1312.
Maier AD, Meddis A, Mirian C, Haslund-Vinding J, Bartek J, Krog SM, Nguyen TUP, Areškeviciute A, Melchior LC, Heegaard S, Kristensen BW, Munch TN, Fugleholm K, Ziebell M, Raleigh DR, Poulsen FR, Gerds TA, Litman T, Scheie D, Mathiesen T. PMID: 36115056; PMCID: PMC10353908.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
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Miat and interacting protein Metadherin maintain a stem-like niche to promote medulloblastoma tumorigenesis and treatment resistance. Proc Natl Acad Sci U S A. 2022 09 13; 119(37):e2203738119.
Peng KL, Vasudevan HN, Lockney DT, Baum R, Hendrickson RC, Raleigh DR, Schmitt AM. PMID: 36067288; PMCID: PMC9478675.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
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Multiplatform molecular analyses refine classification of gliomas arising in patients with neurofibromatosis type 1. Acta Neuropathol. 2022 10; 144(4):747-765.
Lucas CG, Sloan EA, Gupta R, Wu J, Pratt D, Vasudevan HN, Ravindranathan A, Barreto J, Williams EA, Shai A, Whipple NS, Bruggers CS, Maher O, Nabors B, Rodriguez M, Samuel D, Brown M, Carmichael J, Lu R, Mirchia K, Sullivan DV, Pekmezci M, Tihan T, Bollen AW, Perry A, Banerjee A, Mueller S, Gupta N, Hervey-Jumper SL, Oberheim Bush NA, Daras M, Taylor JW, Butowski NA, de Groot J, Clarke JL, Raleigh DR, Costello JF, Phillips JJ, Reddy AT, Chang SM, Berger MS, Solomon DA. PMID: 35945463; PMCID: PMC9468105.
View in:
PubMed Mentions:
21 Fields:
Translation:
Humans
-
View in:
PubMed Mentions:
10
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Intrinsically Disordered Protein Micelles as Vehicles for Convection-Enhanced Drug Delivery to Glioblastoma Multiforme. ACS Appl Bio Mater. 2022 08 15; 5(8):3695-3702.
Gleason JM, Klass SH, Huang P, Ozawa T, Santos RA, Fogarty MM, Raleigh DR, Berger MS, Francis MB. PMID: 35857070.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Targeted Next-Generation Sequencing Reveals Divergent Clonal Evolution in Components of Composite Pleomorphic Xanthoastrocytoma-Ganglioglioma. J Neuropathol Exp Neurol. 2022 07 19; 81(8):650-657.
Lucas CG, Davidson CJ, Alashari M, Putnam AR, Whipple NS, Bruggers CS, Mendez JS, Cheshier SH, Walker JB, Ramani B, Cadwell CR, Sullivan DV, Lu R, Mirchia K, Van Ziffle J, Devine P, Goldschmidt E, Hervey-Jumper SL, Gupta N, Oberheim Bush NA, Raleigh DR, Bollen A, Tihan T, Pekmezci M, Solomon DA, Phillips JJ, Perry A. PMID: 35703914; PMCID: PMC9297094.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
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68Ga-DOTATATE PET: The Future of Meningioma Treatment. Int J Radiat Oncol Biol Phys. 2022 07 15; 113(4):868-871.
Prasad RN, Perlow HK, Bovi J, Braunstein SE, Ivanidze J, Kalapurakal JA, Kleefisch C, Knisely JPS, Mehta MP, Prevedello DM, Raleigh DR, Mishra MV, Roberge D, Rogers CL, Palmer JD. PMID: 35772444.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Intratumor and informatic heterogeneity influence meningioma molecular classification. Acta Neuropathol. 2022 09; 144(3):579-583.
Vasudevan HN, Choudhury A, Hilz S, Villanueva-Meyer JE, Chen WC, Lucas CG, Braunstein SE, Oberheim Bush NA, Butowski N, Pekmezci M, McDermott MW, Perry A, Solomon DA, Magill ST, Raleigh DR. PMID: 35759011; PMCID: PMC9618384.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
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Supervised machine learning algorithms demonstrate proliferation index correlates with long-term recurrence after complete resection of WHO grade I meningioma. J Neurosurg. 2023 01 01; 138(1):86-94.
Nguyen MP, Morshed RA, Dalle Ore CL, Cummins DD, Saggi S, Chen WC, Choudhury A, Ravi A, Raleigh DR, Magill ST, McDermott MW, Theodosopoulos PV. PMID: 36303473; PMCID: PMC10326725.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Adverse radiation effect and freedom from progression following repeat stereotactic radiosurgery for brain metastases. J Neurosurg. 2023 01 01; 138(1):104-112.
Sneed PK, Chan JW, Ma L, Braunstein SE, Theodosopoulos PV, Fogh SE, Nakamura JL, Boreta L, Raleigh DR, Ziemer BP, Morin O, Hervey-Jumper SL, McDermott MW. PMID: 35594891.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansPHPublic Health
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Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities. Nat Genet. 2022 05; 54(5):649-659.
Choudhury A, Magill ST, Eaton CD, Prager BC, Chen WC, Cady MA, Seo K, Lucas CG, Casey-Clyde TJ, Vasudevan HN, Liu SJ, Villanueva-Meyer JE, Lam TC, Pu JK, Li LF, Leung GK, Swaney DL, Zhang MY, Chan JW, Qiu Z, Martin MV, Susko MS, Braunstein SE, Bush NAO, Schulte JD, Butowski N, Sneed PK, Berger MS, Krogan NJ, Perry A, Phillips JJ, Solomon DA, Costello JF, McDermott MW, Rich JN, Raleigh DR. PMID: 35534562; PMCID: PMC9374001.
View in:
PubMed Mentions:
138 Fields:
Translation:
HumansCells
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A molecularly integrated grade for meningioma. Neuro Oncol. 2022 05 04; 24(5):796-808.
Driver J, Hoffman SE, Tavakol S, Woodward E, Maury EA, Bhave V, Greenwald NF, Nassiri F, Aldape K, Zadeh G, Choudhury A, Vasudevan HN, Magill ST, Raleigh DR, Abedalthagafi M, Aizer AA, Alexander BM, Ligon KL, Reardon DA, Wen PY, Al-Mefty O, Ligon AH, Dubuc AM, Beroukhim R, Claus EB, Dunn IF, Santagata S, Bi WL. PMID: 34508644; PMCID: PMC9071299.
View in:
PubMed Mentions:
100 Fields:
Translation:
Humans
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CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids. Nat Commun. 2022 05 03; 13(1):2407.
Lo M, Sharir A, Paul MD, Torosyan H, Agnew C, Li A, Neben C, Marangoni P, Xu L, Raleigh DR, Jura N, Klein OD. PMID: 35504891; PMCID: PMC9065090.
View in:
PubMed Mentions:
5 Fields:
Translation:
Cells
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Pediatric pineoblastoma: A pooled outcome study of North American and Australian therapeutic data. Neurooncol Adv. 2022 Jan-Dec; 4(1):vdac056.
Hansford JR, Huang J, Endersby R, Dodgshun AJ, Li BK, Hwang E, Leary S, Gajjar A, Von Hoff K, Wells O, Wray A, Kotecha RS, Raleigh DR, Stoller S, Mueller S, Schild SE, Bandopadhayay P, Fouladi M, Bouffet E, Huang A, Onar-Thomas A, Gottardo NG. PMID: 35664557; PMCID: PMC9154333.
View in:
PubMed Mentions:
8
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Resection with intraoperative cesium-131 brachytherapy as salvage therapy for recurrent brain tumors. J Neurosurg. 2022 Oct 01; 137(4):924-930.
Chen WC, Lafreniere M, Phuong C, Liu SJ, Baal JD, Lometti M, Morin O, Ziemer B, Vasudevan HN, Lucas CG, Hervey-Jumper SL, Theodosopoulos PV, Magill ST, Fogh S, Nakamura JL, Boreta L, Sneed PK, McDermott MW, Raleigh DR, Braunstein SE. PMID: 35061986.
View in:
PubMed Mentions:
11 Fields:
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ATRX regulates glial identity and the tumor microenvironment in IDH-mutant glioma. Genome Biol. 2021 11 11; 22(1):311.
Babikir H, Wang L, Shamardani K, Catalan F, Sudhir S, Aghi MK, Raleigh DR, Phillips JJ, Diaz AA. PMID: 34763709; PMCID: PMC8588616.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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Synthesis and Preliminary Biological Assessment of Carborane-Loaded Theranostic Nanoparticles to Target Prostate-Specific Membrane Antigen. ACS Appl Mater Interfaces. 2021 Nov 24; 13(46):54739-54752.
Meher N, Seo K, Wang S, Bidkar AP, Fogarty M, Dhrona S, Huang X, Tang R, Blaha C, Evans MJ, Raleigh DR, Jun YW, VanBrocklin HF, Desai TA, Wilson DM, Ozawa T, Flavell RR. PMID: 34752058.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
-
View in:
PubMed Mentions:
96
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Efficacy and Safety of Stereotactic Radiosurgery for Brainstem Metastases: A Systematic Review and Meta-analysis. JAMA Oncol. 2021 Jul 01; 7(7):1033-1040.
Chen WC, Baal UH, Baal JD, Pai JS, Boreta L, Braunstein SE, Raleigh DR. PMID: 33983393; PMCID: PMC8120444.
View in:
PubMed Mentions:
25 Fields:
Translation:
Humans
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Residents-as-Teachers Curriculum for Radiation Oncology: A Targeted Needs Assessment. Int J Radiat Oncol Biol Phys. 2021 11 01; 111(3):638-642.
Ni L, Thomas HR, Raleigh DR, Boreta LC, Park CC, Braunstein SE. PMID: 34153380.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
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Letter: Patterns of Intermediate- and High-Risk Meningioma Recurrence After Treatment With Postoperative External Beam Radiotherapy. Neurosurgery. 2021 06 15; 89(1):E99-E101.
Susko MS, Chen WC, Vasudevan HN, Magill ST, Lucas CG, Oberheim Bush NA, Solomon DA, Theodosopoulos PV, McDermott MW, Villanueva-Meyer JE, Boreta L, Nakamura JL, Sneed PK, Braunstein SE, Raleigh DR. PMID: 33887769; PMCID: PMC8203419.
View in:
PubMed Mentions:
1 Fields:
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A single institution retrospective analysis on survival based on treatment paradigms for patients with anaplastic oligodendroglioma. J Neurooncol. 2021 Jul; 153(3):447-454.
Bush NAO, Young JS, Zhang Y, Dalle Ore CL, Molinaro AM, Taylor J, Clarke J, Prados M, Braunstein SE, Raleigh DR, Chang SM, Berger MS, Butowski NA. PMID: 34125374; PMCID: PMC8279971.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Sterol regulation of developmental and oncogenic Hedgehog signaling. Biochem Pharmacol. 2022 02; 196:114647.
Daggubati V, Raleigh DR, Sever N. PMID: 34111427; PMCID: PMC8648856.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Smoothened-activating lipids drive resistance to CDK4/6 inhibition in Hedgehog-associated medulloblastoma cells and preclinical models. J Clin Invest. 2021 03 15; 131(6).
Daggubati V, Hochstelter J, Bommireddy A, Choudhury A, Krup AL, Kaur P, Tong P, Li A, Xu L, Reiter JF, Raleigh DR. PMID: 33476305; PMCID: PMC7954583.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway. J Cell Biol. 2021 01 04; 220(1).
Findakly S, Daggubati V, Garcia G, LaStella SA, Choudhury A, Tran C, Li A, Tong P, Garcia JQ, Puri N, Reiter JF, Xu L, Raleigh DR. PMID: 33284321; PMCID: PMC7721912.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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A Prognostic Gene-Expression Signature and Risk Score for Meningioma Recurrence After Resection. Neurosurgery. 2020 12 15; 88(1):202-210.
Chen WC, Vasudevan HN, Choudhury A, Pekmezci M, Lucas CG, Phillips J, Magill ST, Susko MS, Braunstein SE, Oberheim Bush NA, Boreta L, Nakamura JL, Villanueva-Meyer JE, Sneed PK, Perry A, McDermott MW, Solomon DA, Theodosopoulos PV, Raleigh DR. PMID: 32860417; PMCID: PMC7735867.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Histopathologic findings in malignant peripheral nerve sheath tumor predict response to radiotherapy and overall survival. Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa131.
Lucas CG, Vasudevan HN, Chen WC, Magill ST, Braunstein SE, Jacques L, Dahiya S, Rodriguez FJ, Horvai AE, Perry A, Pekmezci M, Raleigh DR. PMID: 33880447; PMCID: PMC8044670.
View in:
PubMed Mentions:
14
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Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma. Nat Commun. 2020 09 23; 11(1):4803.
Magill ST, Vasudevan HN, Seo K, Villanueva-Meyer JE, Choudhury A, John Liu S, Pekmezci M, Findakly S, Hilz S, Lastella S, Demaree B, Braunstein SE, Bush NAO, Aghi MK, Theodosopoulos PV, Sneed PK, Abate AR, Berger MS, McDermott MW, Lim DA, Ullian EM, Costello JF, Raleigh DR. PMID: 32968068; PMCID: PMC7511976.
View in:
PubMed Mentions:
53 Fields:
Translation:
HumansCells
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WHO Grade I Meningioma Recurrence: Identifying High Risk Patients Using Histopathological Features and the MIB-1 Index. Front Oncol. 2020; 10:1522.
Haddad AF, Young JS, Kanungo I, Sudhir S, Chen JS, Raleigh DR, Magill ST, McDermott MW, Aghi MK. PMID: 32983999; PMCID: PMC7483477.
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PubMed Mentions:
37
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The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies. Cancer Discov. 2020 11; 10(11):1722-1741.
Prager BC, Vasudevan HN, Dixit D, Bernatchez JA, Wu Q, Wallace LC, Bhargava S, Lee D, King BH, Morton AR, Gimple RC, Pekmezci M, Zhu Z, Siqueira-Neto JL, Wang X, Xie Q, Chen C, Barnett GH, Vogelbaum MA, Mack SC, Chavez L, Perry A, Raleigh DR, Rich JN. PMID: 32703768; PMCID: PMC8194360.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Meningioma cells express primary cilia but do not transduce ciliary Hedgehog signals. Acta Neuropathol Commun. 2020 07 20; 8(1):114.
Findakly S, Choudhury A, Daggubati V, Pekmezci M, Lang UE, Raleigh DR. PMID: 32690089; PMCID: PMC7370519.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma. Genome Biol. 2020 03 31; 21(1):83.
Liu SJ, Malatesta M, Lien BV, Saha P, Thombare SS, Hong SJ, Pedraza L, Koontz M, Seo K, Horlbeck MA, He D, Birk HS, Jain M, Olsen HE, Akeson M, Weissman JS, Monje M, Gupta N, Raleigh DR, Ullian EM, Lim DA. PMID: 32234056; PMCID: PMC7110660.
View in:
PubMed Mentions:
75 Fields:
Translation:
HumansCells
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Multiplatform Molecular Profiling Reveals Epigenomic Intratumor Heterogeneity in Ependymoma. Cell Rep. 2020 02 04; 30(5):1300-1309.e5.
Liu SJ, Magill ST, Vasudevan HN, Hilz S, Villanueva-Meyer JE, Lastella S, Daggubati V, Spatz J, Choudhury A, Orr BA, Demaree B, Seo K, Ferris SP, Abate AR, Oberheim Bush NA, Bollen AW, McDermott MW, Costello JF, Raleigh DR. PMID: 32023450; PMCID: PMC7313374.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Clinical Implications of Primary Cilia in Skin Cancer. Dermatol Ther (Heidelb). 2020 Apr; 10(2):233-248.
Choudhury A, Neumann NM, Raleigh DR, Lang UE. PMID: 31997226; PMCID: PMC7090118.
View in:
PubMed Mentions:
5
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Stereotactic Body Radiation Therapy of Adrenal Metastases: A Pooled Meta-Analysis and Systematic Review of 39 Studies with 1006 Patients. Int J Radiat Oncol Biol Phys. 2020 05 01; 107(1):48-61.
Chen WC, Baal JD, Baal U, Pai J, Gottschalk A, Boreta L, Braunstein SE, Raleigh DR. PMID: 32001383; PMCID: PMC8177042.
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PubMed Mentions:
36 Fields:
Translation:
Humans
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Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma. Cell Stem Cell. 2020 01 02; 26(1):48-63.e6.
Bhaduri A, Di Lullo E, Jung D, Müller S, Crouch EE, Espinosa CS, Ozawa T, Alvarado B, Spatazza J, Cadwell CR, Wilkins G, Velmeshev D, Liu SJ, Malatesta M, Andrews MG, Mostajo-Radji MA, Huang EJ, Nowakowski TJ, Lim DA, Diaz A, Raleigh DR, Kriegstein AR. PMID: 31901251; PMCID: PMC7029801.
View in:
PubMed Mentions:
188 Fields:
Translation:
HumansCells
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Preclinical models of meningioma: Cell culture and animal systems. Handb Clin Neurol. 2020; 169:131-136.
Choudhury A, Raleigh DR. PMID: 32553284.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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Stereotactic Radiosurgery to More Than 10 Brain Metastases: Evidence to Support the Role of Radiosurgery for Ideal Hippocampal Sparing in the Treatment of Multiple Brain Metastases. World Neurosurg. 2020 Mar; 135:e174-e180.
Susko MS, Garcia MA, Ma L, Nakamura JL, Raleigh DR, Fogh S, Theodosopoulos P, McDermott M, Sneed PK, Braunstein SE. PMID: 31785436; PMCID: PMC8152323.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
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Recurrent non-canonical histone H3 mutations in spinal cord diffuse gliomas. Acta Neuropathol. 2019 11; 138(5):877-881.
Sloan EA, Cooney T, Oberheim Bush NA, Buerki R, Taylor J, Clarke JL, Torkildson J, Kline C, Reddy A, Mueller S, Banerjee A, Butowski N, Chang S, Mummaneni PV, Chou D, Tan L, Theodosopoulos P, McDermott M, Berger M, Raffel C, Gupta N, Sun PP, Li Y, Shah V, Cha S, Braunstein S, Raleigh DR, Samuel D, Scharnhorst D, Fata C, Guo H, Moes G, Kim JYH, Koschmann C, Van Ziffle J, Onodera C, Devine P, Grenert JP, Lee JC, Pekmezci M, Phillips JJ, Tihan T, Bollen AW, Perry A, Solomon DA. PMID: 31515627; PMCID: PMC6818961.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
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Integrated models incorporating radiologic and radiomic features predict meningioma grade, local failure, and overall survival. Neurooncol Adv. 2019 May-Dec; 1(1):vdz011.
Morin O, Chen WC, Nassiri F, Susko M, Magill ST, Vasudevan HN, Wu A, Vallières M, Gennatas ED, Valdes G, Pekmezci M, Alcaide-Leon P, Choudhury A, Interian Y, Mortezavi S, Turgutlu K, Bush NAO, Solberg TD, Braunstein SE, Sneed PK, Perry A, Zadeh G, McDermott MW, Villanueva-Meyer JE, Raleigh DR. PMID: 31608329; PMCID: PMC6777505.
View in:
PubMed Mentions:
64
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Synthesis and Initial Biological Evaluation of Boron-Containing Prostate-Specific Membrane Antigen Ligands for Treatment of Prostate Cancer Using Boron Neutron Capture Therapy. Mol Pharm. 2019 09 03; 16(9):3831-3841.
Wang S, Blaha C, Santos R, Huynh T, Hayes TR, Beckford-Vera DR, Blecha JE, Hong AS, Fogarty M, Hope TA, Raleigh DR, Wilson DM, Evans MJ, VanBrocklin HF, Ozawa T, Flavell RR. PMID: 31381351; PMCID: PMC6722010.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Clinical, radiological, and histopathological predictors for long-term prognosis after surgery for atypical meningiomas. Acta Neurochir (Wien). 2019 08; 161(8):1647-1656.
Streckert EMS, Hess K, Sporns PB, Adeli A, Brokinkel C, Kriz J, Holling M, Eich HT, Paulus W, Spille DC, van Eck ATCJ, Raleigh DR, McDermott MW, Stummer W, Brokinkel B. PMID: 31147831.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
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Reirradiation of recurrent high-grade glioma and development of prognostic scores for progression and survival. Neurooncol Pract. 2019 Sep; 6(5):364-374.
Chapman CH, Hara JH, Molinaro AM, Clarke JL, Oberheim Bush NA, Taylor JW, Butowski NA, Chang SM, Fogh SE, Sneed PK, Nakamura JL, Raleigh DR, Braunstein SE. PMID: 31555451; PMCID: PMC6753361.
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PubMed Mentions:
22
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Meningioma metastases: incidence and proposed screening paradigm. J Neurosurg. 2020 05 01; 132(5):1447-1455.
Dalle Ore CL, Magill ST, Yen AJ, Shahin MN, Lee DS, Lucas CG, Chen WC, Viner JA, Aghi MK, Theodosopoulos PV, Raleigh DR, Villanueva-Meyer JE, McDermott MW. PMID: 30952122.
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PubMed Mentions:
40 Fields:
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Temozolomide Treatment Induces lncRNA MALAT1 in an NF-κB and p53 Codependent Manner in Glioblastoma. Cancer Res. 2019 05 15; 79(10):2536-2548.
Voce DJ, Bernal GM, Wu L, Crawley CD, Zhang W, Mansour NM, Cahill KE, Szymura SJ, Uppal A, Raleigh DR, Spretz R, Nunez L, Larsen G, Khodarev NN, Weichselbaum RR, Yamini B. PMID: 30940658; PMCID: PMC6522287.
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PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
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Preoperative Dural Contact and Recurrence Risk After Surgical Cavity Stereotactic Radiosurgery for Brain Metastases: New Evidence in Support of Consensus Guidelines. Adv Radiat Oncol. 2019 Jul-Sep; 4(3):458-465.
Susko M, Yu Y, Ma L, Nakamura J, Fogh S, Raleigh DR, Golden E, Theodosopoulos PV, McDermott MW, Sneed PK, Braunstein SE. PMID: 31360800; PMCID: PMC6639748.
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PubMed Mentions:
7
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Recurrent KBTBD4 small in-frame insertions and absence of DROSHA deletion or DICER1 mutation differentiate pineal parenchymal tumor of intermediate differentiation (PPTID) from pineoblastoma. Acta Neuropathol. 2019 05; 137(5):851-854.
Lee JC, Mazor T, Lao R, Wan E, Diallo AB, Hill NS, Thangaraj N, Wendelsdorf K, Samuel D, Kline CN, Banerjee A, Auguste K, Raffel C, Gupta N, Berger M, Raleigh DR, Shai A, Phillips JJ, Bollen AW, Tihan T, Perry A, Costello J, Solomon DA. PMID: 30877433; PMCID: PMC6483828.
View in:
PubMed Mentions:
31 Fields:
Translation:
Humans
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Preoperative MR Imaging to Differentiate Chordoid Meningiomas from Other Meningioma Histologic Subtypes. AJNR Am J Neuroradiol. 2019 03; 40(3):433-439.
Baal JD, Chen WC, Solomon DA, Pai JS, Lucas CH, Hara JH, Oberheim Bush NA, McDermott MW, Raleigh DR, Villanueva-Meyer JE. PMID: 30819773; PMCID: PMC6420369.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
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Misactivation of Hedgehog signaling causes inherited and sporadic cancers. J Clin Invest. 2019 02 01; 129(2):465-475.
Raleigh DR, Reiter JF. PMID: 30707108; PMCID: PMC6355229.
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PubMed Mentions:
54 Fields:
Translation:
HumansAnimalsCells
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Advances in multidisciplinary therapy for meningiomas. Neuro Oncol. 2019 01 14; 21(Suppl 1):i18-i31.
Brastianos PK, Galanis E, Butowski N, Chan JW, Dunn IF, Goldbrunner R, Herold-Mende C, Ippen FM, Mawrin C, McDermott MW, Sloan A, Snyder J, Tabatabai G, Tatagiba M, Tonn JC, Wen PY, Aldape K, Nassiri F, Zadeh G, Jenkinson MD, Raleigh DR, International Consortium on Meningiomas. PMID: 30649489; PMCID: PMC6347080.
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PubMed Mentions:
89 Fields:
Translation:
Humans
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Erratum: "Machine learning algorithms for outcome prediction in (chemo)radiotherapy: An empirical comparison of classifiers" [Med. Phys. 45 (7), 3449-3459 (2018)]. Med Phys. 2019 Feb; 46(2):1080-1087.
Deist TM, Dankers FJWM, Valdes G, Wijsman R, Hsu IC, Oberije C, Lustberg T, van Soest J, Hoebers F, Jochems A, El Naqa I, Wee L, Morin O, Raleigh DR, Bots W, Kaanders JH, Belderbos J, Kwint M, Solberg T, Monshouwer R, Bussink J, Dekker A, Lambin P. PMID: 30730570; PMCID: PMC11078197.
View in:
PubMed Mentions:
4 Fields:
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The impact of histopathology and NAB2-STAT6 fusion subtype in classification and grading of meningeal solitary fibrous tumor/hemangiopericytoma. Acta Neuropathol. 2019 02; 137(2):307-319.
Fritchie K, Jensch K, Moskalev EA, Caron A, Jenkins S, Link M, Brown PD, Rodriguez FJ, Guajardo A, Brat D, Velázquez Vega JE, Perry A, Wu A, Raleigh DR, Santagata S, Louis DN, Brastianos PK, Kaplan A, Alexander BM, Rossi S, Ferrarese F, Haller F, Giannini C. PMID: 30584643; PMCID: PMC6513906.
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PubMed Mentions:
33 Fields:
Translation:
Humans
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Surgical outcomes after reoperation for recurrent non-skull base meningiomas. J Neurosurg. 2019 10 01; 131(4):1179-1187.
Magill ST, Dalle Ore CL, Diaz MA, Jalili DD, Raleigh DR, Aghi MK, Theodosopoulos PV, McDermott MW. PMID: 30544357.
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PubMed Mentions:
22 Fields:
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Cilia-Associated Oxysterols Activate Smoothened. Mol Cell. 2018 10 18; 72(2):316-327.e5.
Raleigh DR, Sever N, Choksi PK, Sigg MA, Hines KM, Thompson BM, Elnatan D, Jaishankar P, Bisignano P, Garcia-Gonzalo FR, Krup AL, Eberl M, Byrne EFX, Siebold C, Wong SY, Renslo AR, Grabe M, McDonald JG, Xu L, Beachy PA, Reiter JF. PMID: 30340023; PMCID: PMC6503851.
View in:
PubMed Mentions:
67 Fields:
Translation:
HumansAnimalsCells
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Preoperative and postoperative prediction of long-term meningioma outcomes. PLoS One. 2018; 13(9):e0204161.
Gennatas ED, Wu A, Braunstein SE, Morin O, Chen WC, Magill ST, Gopinath C, Villaneueva-Meyer JE, Perry A, McDermott MW, Solberg TD, Valdes G, Raleigh DR. PMID: 30235308; PMCID: PMC6147484.
View in:
PubMed Mentions:
21 Fields:
Translation:
Humans
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Machine learning algorithms for outcome prediction in (chemo)radiotherapy: An empirical comparison of classifiers. Med Phys. 2018 Jul; 45(7):3449-3459.
Deist TM, Dankers FJWM, Valdes G, Wijsman R, Hsu IC, Oberije C, Lustberg T, van Soest J, Hoebers F, Jochems A, El Naqa I, Wee L, Morin O, Raleigh DR, Bots W, Kaanders JH, Belderbos J, Kwint M, Solberg T, Monshouwer R, Bussink J, Dekker A, Lambin P. PMID: 29763967; PMCID: PMC6095141.
View in:
PubMed Mentions:
147 Fields:
Translation:
Humans
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Clinical Applications of Quantitative 3-Dimensional MRI Analysis for Pediatric Embryonal Brain Tumors. Int J Radiat Oncol Biol Phys. 2018 11 15; 102(4):744-756.
Hara JH, Wu A, Villanueva-Meyer JE, Valdes G, Daggubati V, Mueller S, Solberg TD, Braunstein SE, Morin O, Raleigh DR. PMID: 30108003.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
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Surgical Outcomes, Complications, and Management Strategies for Foramen Magnum Meningiomas. J Neurol Surg B Skull Base. 2019 Feb; 80(1):1-9.
Magill ST, Shahin MN, Lucas CG, Yen AJ, Lee DS, Raleigh DR, Aghi MK, Theodosopoulos PV, McDermott MW. PMID: 30733894; PMCID: PMC6365236.
View in:
PubMed Mentions:
5
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Surgical outcomes after reoperation for recurrent skull base meningiomas. J Neurosurg. 2019 03 01; 130(3):876-883.
Magill ST, Lee DS, Yen AJ, Lucas CG, Raleigh DR, Aghi MK, Theodosopoulos PV, McDermott MW. PMID: 29726777.
View in:
PubMed Mentions:
30 Fields:
Translation:
Humans
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How the Ciliary Membrane Is Organized Inside-Out to Communicate Outside-In. Curr Biol. 2018 04 23; 28(8):R421-R434.
Garcia G, Raleigh DR, Reiter JF. PMID: 29689227; PMCID: PMC6434934.
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PubMed Mentions:
96 Fields:
Translation:
HumansAnimalsCells
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Histopathological features predictive of local control of atypical meningioma after surgery and adjuvant radiotherapy. J Neurosurg. 2018 04 06; 130(2):443-450.
Chen WC, Magill ST, Wu A, Vasudevan HN, Morin O, Aghi MK, Theodosopoulos PV, Perry A, McDermott MW, Sneed PK, Braunstein SE, Raleigh DR. PMID: 29624151.
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PubMed Mentions:
30 Fields:
Translation:
Humans
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View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
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Comprehensive Molecular Profiling Identifies FOXM1 as a Key Transcription Factor for Meningioma Proliferation. Cell Rep. 2018 03 27; 22(13):3672-3683.
Vasudevan HN, Braunstein SE, Phillips JJ, Pekmezci M, Tomlin BA, Wu A, Reis GF, Magill ST, Zhang J, Feng FY, Nicholaides T, Chang SM, Sneed PK, McDermott MW, Berger MS, Perry A, Raleigh DR. PMID: 29590631; PMCID: PMC8204688.
View in:
PubMed Mentions:
74 Fields:
Translation:
HumansCells
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Salvage therapy outcomes for atypical meningioma. J Neurooncol. 2018 Jun; 138(2):425-433.
Chen WC, Hara J, Magill ST, Wu A, Aghi MK, Theodosopoulos PV, Perry A, McDermott MW, Sneed PK, Raleigh DR, Braunstein SE. PMID: 29480505.
View in:
PubMed Mentions:
20 Fields:
Translation:
Humans
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Resection Cavity Contraction Effects in the Use of Radioactive Sources (1-25 versus Cs-131) for Intra-Operative Brain Implants. Cureus. 2018 Jan 16; 10(1):e2079.
Han DY, Ma L, Braunstein S, Raleigh D, Sneed PK, McDermott M. PMID: 29560292; PMCID: PMC5856410.
View in:
PubMed Mentions:
9
-
View in:
PubMed Mentions:
30 Fields:
Translation:
Humans
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Hedgehog signaling drives medulloblastoma growth via CDK6. J Clin Invest. 2018 01 02; 128(1):120-124.
Raleigh DR, Choksi PK, Krup AL, Mayer W, Santos N, Reiter JF. PMID: 29202464; PMCID: PMC5749513.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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Multiple myeloma and a mischievous pacemaker: A teaching case involving irradiation of a cardiovascular implantable electronic device. Pract Radiat Oncol. 2018 Mar - Apr; 8(2):90-94.
Lloyd S, Morin O, Whitman I, Raleigh D, Fogh S, Menzel P. PMID: 29331513.
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PubMed Mentions: Fields:
Translation:
Humans
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Case-based review: pediatric medulloblastoma. Neurooncol Pract. 2017 Sep; 4(3):138-150.
Kline CN, Packer RJ, Hwang EI, Raleigh DR, Braunstein S, Raffel C, Bandopadhayay P, Solomon DA, Aboian M, Cha S, Mueller S. PMID: 29692919; PMCID: PMC5909805.
View in:
PubMed Mentions:
15
-
View in:
PubMed Mentions:
14
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Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy. Neuro Oncol. 2017 05 01; 19(5):699-709.
Kline CN, Joseph NM, Grenert JP, van Ziffle J, Talevich E, Onodera C, Aboian M, Cha S, Raleigh DR, Braunstein S, Torkildson J, Samuel D, Bloomer M, Campomanes AGA, Banerjee A, Butowski N, Raffel C, Tihan T, Bollen AW, Phillips JJ, Korn WM, Yeh I, Bastian BC, Gupta N, Mueller S, Perry A, Nicolaides T, Solomon DA. PMID: 28453743; PMCID: PMC5464451.
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PubMed Mentions:
156 Fields:
Translation:
Humans
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Pediatric high-grade glioma: current molecular landscape and therapeutic approaches. J Neurooncol. 2017 Sep; 134(3):541-549.
Braunstein S, Raleigh D, Bindra R, Mueller S, Haas-Kogan D. PMID: 28357536.
View in:
PubMed Mentions:
78 Fields:
Translation:
Humans
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Surgical Resection and Interstitial Iodine-125 Brachytherapy for High-Grade Meningiomas: A 25-Year Series. Neurosurgery. 2017 03 01; 80(3):409-416.
Magill ST, Lau D, Raleigh DR, Sneed PK, Fogh SE, McDermott MW. PMID: 27258768.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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Survival after chemotherapy and stem cell transplant followed by delayed craniospinal irradiation is comparable to upfront craniospinal irradiation in pediatric embryonal brain tumor patients. J Neurooncol. 2017 01; 131(2):359-368.
Raleigh DR, Tomlin B, Buono BD, Roddy E, Sear K, Byer L, Felton E, Banerjee A, Torkildson J, Samuel D, Horn B, Braunstein SE, Haas-Kogan DA, Mueller S. PMID: 27778212.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Educational Impact of a Structured Radiation Oncology Clerkship Curriculum: An Interinstitutional Comparison. J Am Coll Radiol. 2017 Jan; 14(1):96-102.
Oskvarek JJ, Brower JV, Mohindra P, Raleigh DR, Chmura SJ, Golden DW. PMID: 27652570; PMCID: PMC5222702.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
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Resection and brain brachytherapy with permanent iodine-125 sources for brain metastasis. J Neurosurg. 2017 Jun; 126(6):1749-1755.
Raleigh DR, Seymour ZA, Tomlin B, Theodosopoulos PV, Berger MS, Aghi MK, Geneser SE, Krishnamurthy D, Fogh SE, Sneed PK, McDermott MW. PMID: 27367240.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Discovery of additional brain metastases on the day of stereotactic radiosurgery: risk factors and outcomes. J Neurosurg. 2017 Jun; 126(6):1756-1763.
Garcia MA, Lazar A, Duriseti S, Raleigh DR, Hess CP, Fogh SE, Barani IJ, Nakamura JL, Larson DA, Theodosopoulos P, McDermott M, Sneed PK, Braunstein S. PMID: 27367235.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
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Histopathologic review of pineal parenchymal tumors identifies novel morphologic subtypes and prognostic factors for outcome. Neuro Oncol. 2017 01; 19(1):78-88.
Raleigh DR, Solomon DA, Lloyd SA, Lazar A, Garcia MA, Sneed PK, Clarke JL, McDermott MW, Berger MS, Tihan T, Haas-Kogan DA. PMID: 27282397; PMCID: PMC5193017.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
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View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
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Meningiomas With Rhabdoid Features Lacking Other Histologic Features of Malignancy: A Study of 44 Cases and Review of the Literature. J Neuropathol Exp Neurol. 2016 Jan; 75(1):44-52.
Vaubel RA, Chen SG, Raleigh DR, Link MJ, Chicoine MR, Barani I, Jenkins SM, Aleff PA, Rodriguez FJ, Burger PC, Dahiya S, Perry A, Giannini C. PMID: 26705409; PMCID: PMC5009417.
View in:
PubMed Mentions:
35 Fields:
Translation:
Humans
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Somatostatin receptor 2a is a more sensitive diagnostic marker of meningioma than epithelial membrane antigen. Acta Neuropathol. 2015 Sep; 130(3):441-3.
Menke JR, Raleigh DR, Gown AM, Thomas S, Perry A, Tihan T. PMID: 26195322.
View in:
PubMed Mentions:
63 Fields:
Translation:
Humans
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Patient- and treatment-specific predictors of genitourinary function after high-dose-rate monotherapy for favorable prostate cancer. Brachytherapy. 2015 Nov-Dec; 14(6):795-800.
Raleigh DR, Chang AJ, Tomlin B, Cunha JA, Braunstein SE, Shinohara K, Gottschalk AR, Roach M, Hsu IC. PMID: 26198421.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Induction Hedgehog pathway inhibition followed by combined-modality radiotherapy for basal cell carcinoma. Br J Dermatol. 2015 Aug; 173(2):544-6.
Raleigh DR, Algazi A, Arron ST, Neuhaus IM, Yom SS. PMID: 25702621.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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The management of central neurocytoma: radiotherapy. Neurosurg Clin N Am. 2015 Jan; 26(1):45-56.
Barani IJ, Raleigh DR, Larson D. PMID: 25432183.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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S-phase-dependent p50/NF-кB1 phosphorylation in response to ATR and replication stress acts to maintain genomic stability. Cell Cycle. 2015; 14(4):566-76.
Crawley CD, Kang S, Bernal GM, Wahlstrom JS, Voce DJ, Cahill KE, Garofalo A, Raleigh DR, Weichselbaum RR, Yamini B. PMID: 25590437; PMCID: PMC4614791.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Toward an improved understanding of the ionizing radiation induced DNA damage/response networks in human malignancies. Front Oncol. 2014; 4:335.
Haas-Kogan DA, Raleigh DR, Dicker AP. PMID: 25538888; PMCID: PMC4255519.
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Non-Muscle Myosin IIa Heavy Chain Links Squamous-Cell Carcinoma of the Head and Neck to the DNA Damage Response. Front Oncol. 2014; 4:228.
Raleigh DR, Haas-Kogan DA. PMID: 25202680; PMCID: PMC4142340.
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A national radiation oncology medical student clerkship survey: didactic curricular components increase confidence in clinical competency. Int J Radiat Oncol Biol Phys. 2014 Jan 01; 88(1):51-6.
Jagadeesan VS, Raleigh DR, Koshy M, Howard AR, Chmura SJ, Golden DW. PMID: 24331651; PMCID: PMC4262520.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux. Mol Biol Cell. 2013 Oct; 24(19):3056-68.
Buschmann MM, Shen L, Rajapakse H, Raleigh DR, Wang Y, Wang Y, Lingaraju A, Zha J, Abbott E, McAuley EM, Breskin LA, Wu L, Anderson K, Turner JR, Weber CR. PMID: 23924897; PMCID: PMC3784380.
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PubMed Mentions:
102 Fields:
Translation:
HumansCells
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Molecular targets and mechanisms of radiosensitization using DNA damage response pathways. Future Oncol. 2013 Feb; 9(2):219-33.
Raleigh DR, Haas-Kogan DA. PMID: 23414472; PMCID: PMC3635474.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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DNA damage-induced cytotoxicity is mediated by the cooperative interaction of phospho-NF-κB p50 and a single nucleotide in the κB-site. Nucleic Acids Res. 2013 Jan; 41(2):764-74.
Crawley CD, Raleigh DR, Kang S, Voce DJ, Schmitt AM, Weichselbaum RR, Yamini B. PMID: 23180782; PMCID: PMC3553961.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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A genome-wide transgenic resource for conditional expression of Drosophila microRNAs. Development. 2012 Aug; 139(15):2821-31.
Bejarano F, Bortolamiol-Becet D, Dai Q, Sun K, Saj A, Chou YT, Raleigh DR, Kim K, Ni JQ, Duan H, Yang JS, Fulga TA, Van Vactor D, Perrimon N, Lai EC. PMID: 22745315; PMCID: PMC3392707.
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PubMed Mentions:
61 Fields:
Translation:
AnimalsCells
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Radiation oncology fourth-year medical student clerkships: a targeted needs assessment. Int J Radiat Oncol Biol Phys. 2013 Feb 01; 85(2):296-7.
Golden DW, Raleigh DR, Chmura SJ, Koshy M, Howard AR. PMID: 22713834.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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p50 (NF-κB1) is an effector protein in the cytotoxic response to DNA methylation damage. Mol Cell. 2011 Dec 09; 44(5):785-96.
Schmitt AM, Crawley CD, Kang S, Raleigh DR, Yu X, Wahlstrom JS, Voce DJ, Darga TE, Weichselbaum RR, Yamini B. PMID: 22152481; PMCID: PMC3240852.
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PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
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Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function. J Cell Biol. 2011 May 02; 193(3):565-82.
Raleigh DR, Boe DM, Yu D, Weber CR, Marchiando AM, Bradford EM, Wang Y, Wu L, Schneeberger EE, Shen L, Turner JR. PMID: 21536752; PMCID: PMC3087007.
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PubMed Mentions:
134 Fields:
Translation:
HumansCells
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Tight junction pore and leak pathways: a dynamic duo. Annu Rev Physiol. 2011; 73:283-309.
Shen L, Weber CR, Raleigh DR, Yu D, Turner JR. PMID: 20936941; PMCID: PMC4655434.
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PubMed Mentions:
432 Fields:
Translation:
HumansAnimalsCells
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MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function. Proc Natl Acad Sci U S A. 2010 May 04; 107(18):8237-41.
Yu D, Marchiando AM, Weber CR, Raleigh DR, Wang Y, Shen L, Turner JR. PMID: 20404178; PMCID: PMC2889526.
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PubMed Mentions:
137 Fields:
Translation:
HumansAnimalsCells
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Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo. J Cell Biol. 2010 Apr 05; 189(1):111-26.
Marchiando AM, Shen L, Graham WV, Weber CR, Schwarz BT, Austin JR, Raleigh DR, Guan Y, Watson AJ, Montrose MH, Turner JR. PMID: 20351069; PMCID: PMC2854371.
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PubMed Mentions:
286 Fields:
Translation:
AnimalsCells
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Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity. J Biol Chem. 2010 Apr 16; 285(16):12037-46.
Weber CR, Raleigh DR, Su L, Shen L, Sullivan EA, Wang Y, Turner JR. PMID: 20177070; PMCID: PMC2852941.
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PubMed Mentions:
167 Fields:
Translation:
HumansAnimalsCells
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Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions. Mol Biol Cell. 2010 Apr 01; 21(7):1200-13.
Raleigh DR, Marchiando AM, Zhang Y, Shen L, Sasaki H, Wang Y, Long M, Turner JR. PMID: 20164257; PMCID: PMC2847524.
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PubMed Mentions:
163 Fields:
Translation:
HumansAnimalsCells
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Risks of cerebrovascular events related to open heart surgery. J Ky Med Assoc. 1998 Aug; 96(8):290-5.
Attum AA, Girardet R, Barbie R, Yared S, Raleigh D, Mathew T, Hymes W, Lansing A. PMID: 9735641.
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Translation:
Humans