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Jennifer Chen, MD

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
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    Collapse Biography 
    Collapse Education and Training
    Harvard College, Cambridge, MAAB06/2003Government
    Harvard Medical School, Boston, MAMD06/2009Doctor of Medicine
    Brigham and Women's Hospital, Boston, MA06/2012Residency in Internal Medicine
    Massachusetts General Hospital, Boston, MA06/2016Fellowship in Gastroenterology and Hepatology

    Collapse Research 
    Collapse Research Activities and Funding
    Role of Ceramide in Hepatic Stellate Cell Activation and Liver Fibrosis
    NIH/NIDDK K08DK114548Sep 1, 2017 - Jul 31, 2022
    Role: Principal Investigator
    Tricyclic Antidepressants Induce Hepatic Stellate Cell Quiescence: Identification of Mechanisms to Halt Hepatic Fibrosis
    NIH/NIDDK F32DK107197Sep 15, 2015 - Sep 14, 2016
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Global Health

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Shava E, Moyo S, Zash R, Diseko M, Dintwa EN, Mupfumi L, Mabuta J, Mayondi G, Chen JY, Lockman S, Mmalane M, Makhema J, Shapiro R. Brief Report: High Rates of Adverse Birth Outcomes in HIV and Syphilis Coinfected Women in Botswana. J Acquir Immune Defic Syndr. 2019 Aug 15; 81(5):e135-e140. PMID: 31295173.
      View in: PubMed
    2. Caniglia EC, Zash R, Jacobson DL, Diseko M, Mayondi G, Lockman S, Chen JY, Mmalane M, Makhema J, Hernán MA, Shapiro RL. Emulating a target trial of antiretroviral therapy regimens started before conception and risk of adverse birth outcomes. AIDS. 2018 Jan 02; 32(1):113-120. PMID: 29112066.
      View in: PubMed
    3. Chen JY, Newcomb B, Zhou C, Pondick JV, Ghoshal S, York SR, Motola DL, Coant N, Yi JK, Mao C, Tanabe KK, Bronova I, Berdyshev EV, Fuchs BC, Hannun Y, Chung RT, Mullen AC. Tricyclic Antidepressants Promote Ceramide Accumulation to Regulate Collagen Production in Human Hepatic Stellate Cells. Sci Rep. 2017 03 21; 7:44867. PMID: 28322247.
      View in: PubMed
    4. Zash R, Souda S, Chen JY, Binda K, Dryden-Peterson S, Lockman S, Mmalane M, Makhema J, Essex M, Shapiro R. Reassuring Birth Outcomes With Tenofovir/Emtricitabine/Efavirenz Used for Prevention of Mother-to-Child Transmission of HIV in Botswana. J Acquir Immune Defic Syndr. 2016 Apr 01; 71(4):428-36. PMID: 26379069.
      View in: PubMed
    5. Zhou C, York SR, Chen JY, Pondick JV, Motola DL, Chung RT, Mullen AC. Long noncoding RNAs expressed in human hepatic stellate cells form networks with extracellular matrix proteins. Genome Med. 2016 Mar 23; 8(1):31. PMID: 27007663.
      View in: PubMed
    6. Dryden-Peterson S, Lockman S, Zash R, Lei Q, Chen JY, Souda S, Petlo C, Dintwa E, Lebelonyane R, Mmalane M, Shapiro RL. Initial programmatic implementation of WHO option B in Botswana associated with increased projected MTCT. J Acquir Immune Defic Syndr. 2015 Mar 01; 68(3):245-9. PMID: 25501611.
      View in: PubMed
    7. Kelly P, Saloojee H, Chen JY, Chung RT. Noncommunicable diseases in HIV infection in low- and middle-income countries: gastrointestinal, hepatic, and nutritional aspects. J Acquir Immune Defic Syndr. 2014 Sep 01; 67 Suppl 1:S79-86. PMID: 25117963.
      View in: PubMed
    8. Chen JY, Feeney ER, Chung RT. HCV and HIV co-infection: mechanisms and management. Nat Rev Gastroenterol Hepatol. 2014 Jun; 11(6):362-71. PMID: 24535328.
      View in: PubMed
    9. Chen JY, Chung RT. Future classes of hepatitis C virus therapeutic agents. Infect Dis Clin North Am. 2012 Dec; 26(4):949-66. PMID: 23083826.
      View in: PubMed
    10. Chen JY, Ribaudo HJ, Souda S, Parekh N, Ogwu A, Lockman S, Powis K, Dryden-Peterson S, Creek T, Jimbo W, Madidimalo T, Makhema J, Essex M, Shapiro RL. Highly active antiretroviral therapy and adverse birth outcomes among HIV-infected women in Botswana. J Infect Dis. 2012 Dec 01; 206(11):1695-705. PMID: 23066160.
      View in: PubMed
    11. Chung RT, Umbleja T, Chen JY, Andersen JW, Butt AA, Sherman KE. Extended therapy with pegylated interferon and weight-based ribavirin for HCV-HIV coinfected patients. HIV Clin Trials. 2012 Mar-Apr; 13(2):70-82. PMID: 22510354.
      View in: PubMed
    12. Matthews LT, Ribaudo HJ, Parekh NK, Chen JY, Binda K, Ogwu A, Makhema J, Souda S, Lockman S, Essex M, Shapiro RL. Birth weight for gestational age norms for a large cohort of infants born to HIV-negative women in Botswana compared with norms for U.S.-born black infants. BMC Pediatr. 2011 Dec 16; 11:115. PMID: 22176889.
      View in: PubMed
    13. Chuang HY, Ng LT, Lin LT, Chang JS, Chen JY, Lin TC, Lin CC. Hydrolysable tannins of tropical almond show antifibrotic effects in TGF-ß1-induced hepatic stellate cells. J Sci Food Agric. 2011 Dec; 91(15):2777-84. PMID: 21725979.
      View in: PubMed
    14. Zhang Y, Lu L, Li HQ, Liu W, Tang ZR, Fang H, Chen JY, Ma Y, Zhao Y, Chen RY, Zhang FJ. Engaging HIV-infected patients in antiretroviral therapy services: CD4 cell count testing after HIV diagnosis from 2005 to 2009 in Yunnan and Guangxi, China. Chin Med J (Engl). 2011 May; 124(10):1488-92. PMID: 21740803.
      View in: PubMed
    15. Chen JY, Chung RT. Can we use the "C" word with confidence? Cure for chronic hepatitis C. Gastroenterology. 2011 Mar; 140(3):766-8. PMID: 21256845.
      View in: PubMed
    16. Chen JY, Ogwu AC, Svab P, Lockman S, Moffat HJ, Gaolathe T, Moilwa S, Størdal K, Dryden-Peterson S, Moffat C, Makhema J, Essex M, Shapiro RL. Antiretroviral treatment initiation among HIV-infected pregnant women with low CD4(+) cell counts in Gaborone, Botswana. J Acquir Immune Defic Syndr. 2010 May 01; 54(1):102-6. PMID: 19864957.
      View in: PubMed
    17. Belkora JK, Loth MK, Chen DF, Chen JY, Volz S, Esserman LJ. Monitoring the implementation of Consultation Planning, Recording, and Summarizing in a breast care center. Patient Educ Couns. 2008 Dec; 73(3):536-43. PMID: 18755564; PMCID: PMC2622737.
      View in: PubMed, PubMed Central
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