John Gordan, MD, PhD

Title(s)Associate Professor, Medicine
SchoolSchool of Medicine
Address1700 4th Street, #308A
San Francisco CA 94158
Phone415-353-9888
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    Collapse Biography 
    Collapse Education and Training
    Harvard College, Boston, MAAB6/2001Biochemistry
    University of Pennsylvania, Philadelphia, PAPhD12/2007Cancer Biology
    University of Pennsylvania, Philadelphia, PAMD5/2009

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Protein kinase A and local signaling in cancer. Biochem J. 2024 Nov 20; 481(22):1659-1677. Rosenthal KJ, Gordan JD, Scott JD. PMID: 39540434.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Changes in alpha-fetoprotein across the systemic therapy continuum in advanced hepatocellular carcinoma-a real-world, multicenter study. Ther Adv Med Oncol. 2024; 16:17588359241297085. Li M, Hannan LM, Goyal L, Bocobo AG, Parks AL, Bauer K, Baiev I, Dinicola C, Gordan JD, Venook AP, Harris WP, Bracci P, Kelley RK. PMID: 39563717; PMCID: PMC11574907.
      View in: PubMed   Mentions:
    3. Human GM-CSF/IL-3 enhance tumor immune infiltration in humanized HCC patient-derived xenografts. bioRxiv. 2024 Oct 31. Weinfurtner K, Tischfield D, McClung G, Crainic J, Gordan J, Jiao J, Furth EE, Li W, Tuzneen Supan E, Nadolski GJ, Hunt SJ, Kaplan DE, Gade TPF. PMID: 39554038; PMCID: PMC11565794.
      View in: PubMed   Mentions:
    4. Cataracts Associated With Fibroblast Growth Factor Receptor Inhibitors for Cholangiocarcinoma. JAMA Ophthalmol. 2024 Oct 24. Kassaye I, Alyafaie A, Zhang K, Lifton J, Gordan JD, Kelley RK, Yung M. PMID: 39446357.
      View in: PubMed   Mentions:    Fields:    
    5. DNAJB1-PRKACA fusion drives fibrolamellar liver cancer through impaired SIK signaling and CRTC2/p300-mediated transcriptional reprogramming. Cancer Discov. 2024 Sep 27. Gritti I, Wan J, Weeresekara V, Vaz JM, Tarantino G, Bryde TH, Vijay V, Kammula AV, Kattel P, Zhu S, Vu P, Chan M, Wu MJ, Gordan JD, Patra KC, Silveira VS, Manguso RT, Wein MN, Ott CJ, Qi J, Liu D, Sakamoto K, Gujral TS, Bardeesy N. PMID: 39326063.
      View in: PubMed   Mentions:    Fields:    
    6. Emerging Therapies for the Management of Human Epidermal Growth Factor Receptor 2-/ERBB2-Altered Advanced Biliary Tract Cancers. J Clin Oncol. 2024 Sep 20; 42(27):3170-3176. Zeme EL, Van Loon K, Kelley RK, Gordan JD. PMID: 39102636.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update Clinical Insights. JCO Oncol Pract. 2024 Aug; 20(8):1035-1039. Rose MG, Kennedy EB, Abou-Alfa GK, Finn RS, Gade T, Kelley RK, Taddei T, Gordan JD. PMID: 38662970.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma. PLoS Genet. 2024 Mar; 20(3):e1011216. Ma RK, Tsai PY, Farghli AR, Shumway A, Kanke M, Gordan JD, Gujral TS, Vakili K, Nukaya M, Noetzli L, Ronnekleiv-Kelly S, Broom W, Barrow J, Sethupathy P. PMID: 38512964; PMCID: PMC11020935.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update. J Clin Oncol. 2024 May 20; 42(15):1830-1850. Gordan JD, Kennedy EB, Abou-Alfa GK, Beal E, Finn RS, Gade TP, Goff L, Gupta S, Guy J, Hoang HT, Iyer R, Jaiyesimi I, Jhawer M, Karippot A, Kaseb AO, Kelley RK, Kortmansky J, Leaf A, Remak WM, Sohal DPS, Taddei TH, Wilson Woods A, Yarchoan M, Rose MG. PMID: 38502889.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    10. Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma. Cell Rep. 2024 Feb 27; 43(2):113678. Lauer SM, Omar MH, Golkowski MG, Kenerson HL, Lee KS, Pascual BC, Lim HC, Forbush K, Smith FD, Gordan JD, Ong SE, Yeung RS, Scott JD. PMID: 38236773; PMCID: PMC10964278.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Preclinical evidence for anaplastic lymphoma kinase inhibitors as novel therapeutic treatments for cholangiocarcinoma. Front Oncol. 2023; 13:1184900. Myint KZ, Sueca-Comes M, Collier P, Balasubramanian B, Venkatraman S, Gordan J, Zaitoun AM, Mukherjee A, Arora A, Larbcharoensub N, Suriyonplengsaeng C, Wongprasert K, Janvilisri T, Gomez D, Grabowska AM, Tohtong R, Bates DO, Yacqub-Usman K. PMID: 38144528; PMCID: PMC10748508.
      View in: PubMed   Mentions: 1  
    12. New Opportunities to Individualize Frontline Therapy in Advanced Stages of Hepatocellular Carcinoma. Drugs. 2023 Aug; 83(12):1091-1109. Gordan JD, Keenan BP, Lim HC, Yarchoan M, Kelley RK. PMID: 37402062.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    13. Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma. bioRxiv. 2023 Jun 28. Lauer SM, Omar MH, Golkowski MG, Kenerson HL, Pascual BC, Forbush K, Smith FD, Gordan J, Ong SE, Yeung RS, Scott JD. PMID: 37425703; PMCID: PMC10327129.
      View in: PubMed   Mentions:
    14. Defining incidence and complications of fibrolamellar liver cancer through tiered computational analysis of clinical data. NPJ Precis Oncol. 2023 Mar 23; 7(1):29. Zack T, Losert KP, Maisel SM, Wild J, Yaqubie A, Herman M, Knox JJ, Mayer RJ, Venook AP, Butte A, O'Neill AF, Abou-Alfa GK, Gordan JD. PMID: 36959495; PMCID: PMC10034241.
      View in: PubMed   Mentions: 3  
    15. Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms. Elife. 2023 01 24; 12. Chan GKL, Maisel S, Hwang YC, Pascual BC, Wolber RRB, Vu P, Patra KC, Bouhaddou M, Kenerson HL, Lim HC, Long D, Yeung RS, Sethupathy P, Swaney DL, Krogan NJ, Turnham RE, Riehle KJ, Scott JD, Bardeesy N, Gordan JD. PMID: 36692000; PMCID: PMC9925115.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    16. EGFR Inhibition Potentiates FGFR Inhibitor Therapy and Overcomes Resistance in FGFR2 Fusion-Positive Cholangiocarcinoma. Cancer Discov. 2022 05 02; 12(5):1378-1395. Wu Q, Zhen Y, Shi L, Vu P, Greninger P, Adil R, Merritt J, Egan R, Wu MJ, Yin X, Ferrone CR, Deshpande V, Baiev I, Pinto CJ, McLoughlin DE, Walmsley CS, Stone JR, Gordan JD, Zhu AX, Juric D, Goyal L, Benes CH, Bardeesy N. PMID: 35420673; PMCID: PMC9064956.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    17. Methods to assess small molecule allosteric modulators of the STRAD pseudokinase. Methods Enzymol. 2022; 667:427-453. Qing T, Liu J, Liu F, Mitchell DC, Beresis RT, Gordan JD. PMID: 35525550.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    18. A framework for fibrolamellar carcinoma research and clinical trials. Nat Rev Gastroenterol Hepatol. 2022 05; 19(5):328-342. Dinh TA, Utria AF, Barry KC, Ma R, Abou-Alfa GK, Gordan JD, Jaffee EM, Scott JD, Zucman-Rossi J, O'Neill AF, Furth ME, Sethupathy P. PMID: 35190728; PMCID: PMC9516439.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    19. Targeting a splicing-mediated drug resistance mechanism in prostate cancer by inhibiting transcriptional regulation by PKCβ1. Oncogene. 2022 03; 41(11):1536-1549. Melnyk JE, Steri V, Nguyen HG, Hwang YC, Gordan JD, Hann B, Feng FY, Shokat KM. PMID: 35087237; PMCID: PMC8913362.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    20. A protein interaction landscape of breast cancer. Science. 2021 Oct; 374(6563):eabf3066. Kim M, Park J, Bouhaddou M, Kim K, Rojc A, Modak M, Soucheray M, McGregor MJ, O'Leary P, Wolf D, Stevenson E, Foo TK, Mitchell D, Herrington KA, Muñoz DP, Tutuncuoglu B, Chen KH, Zheng F, Kreisberg JF, Diolaiti ME, Gordan JD, Coppé JP, Swaney DL, Xia B, van 't Veer L, Ashworth A, Ideker T, Krogan NJ. PMID: 34591612; PMCID: PMC9040556.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    21. Phase II Trial of the Combination of Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma with Tumor Mutation Profiling. Liver Cancer. 2021 Nov; 10(6):561-571. Kelley RK, Joseph NM, Nimeiri HS, Hwang J, Kulik LM, Ngo Z, Behr SC, Onodera C, Zhang K, Bocobo AG, Benson AB, Venook AP, Gordan JD. PMID: 34950179; PMCID: PMC8647100.
      View in: PubMed   Mentions: 7  
    22. STRAD-binding agents and uses thereof. 2021. Gordan JD, Mitchell DC, Beresis RT, Adler M.
    23. Tumor hepatitis B virus RNA identifies a clinically and molecularly distinct subset of hepatocellular carcinoma. PLoS Comput Biol. 2021 02; 17(2):e1008699. Lim HC, Gordan JD. PMID: 33561166; PMCID: PMC7909678.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    24. Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline. J Clin Oncol. 2020 Dec 20; 38(36):4317-4345. Gordan JD, Kennedy EB, Abou-Alfa GK, Beg MS, Brower ST, Gade TP, Goff L, Gupta S, Guy J, Harris WP, Iyer R, Jaiyesimi I, Jhawer M, Karippot A, Kaseb AO, Kelley RK, Knox JJ, Kortmansky J, Leaf A, Remak WM, Shroff RT, Sohal DPS, Taddei TH, Venepalli NK, Wilson A, Zhu AX, Rose MG. PMID: 33197225.
      View in: PubMed   Mentions: 289     Fields:    Translation:HumansCTClinical Trials
    25. Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells. Cancer Cell. 2020 07 13; 38(1):129-143.e7. Coles GL, Cristea S, Webber JT, Levin RS, Moss SM, He A, Sangodkar J, Hwang YC, Arand J, Drainas AP, Mooney NA, Demeter J, Spradlin JN, Mauch B, Le V, Shue YT, Ko JH, Lee MC, Kong C, Nomura DK, Ohlmeyer M, Swaney DL, Krogan NJ, Jackson PK, Narla G, Gordan JD, Shokat KM, Sage J. PMID: 32531271; PMCID: PMC7363571.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    26. A Multicenter Randomized Three-Arm Phase II Study of (1) Everolimus, (2) Estrogen Deprivation Therapy (EDT) with Leuprolide + Letrozole, and (3) Everolimus + EDT in Patients with Unresectable Fibrolamellar Carcinoma. Oncologist. 2020 11; 25(11):925-e1603. El Dika I, Mayer RJ, Venook AP, Capanu M, LaQuaglia MP, Kobos R, O'Neill AF, Chou JF, Ly M, Ang C, O'Reilly EM, Gordan JD, Abou-Alfa GK. PMID: 32400000; PMCID: PMC7648371.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    27. Checkpoint Inhibitors for the Treatment of Advanced Hepatocellular Carcinoma. Clin Liver Dis (Hoboken). 2020 Feb; 15(2):53-58. Huppert LA, Gordan JD, Kelley RK. PMID: 32226615; PMCID: PMC7098670.
      View in: PubMed   Mentions: 16  
    28. Phase II Multicenter, Open-Label Study of Oral ENMD-2076 for the Treatment of Patients with Advanced Fibrolamellar Carcinoma. Oncologist. 2020 12; 25(12):e1837-e1845. Abou-Alfa GK, Mayer R, Venook AP, O'Neill AF, Beg MS, LaQuaglia M, Kingham PT, Kobos R, Basturk O, Brennan C, Yopp A, Harding JJ, Leong S, Crown J, Hoti E, Leonard G, Ly M, Bradley M, Valentino E, Markowitz D, Zukiwski A, Ren K, Gordan JD. PMID: 32154962; PMCID: PMC8186410.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    29. A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS. Elife. 2019 09 03; 8. McMahon M, Contreras A, Holm M, Uechi T, Forester CM, Pang X, Jackson C, Calvert ME, Chen B, Quigley DA, Luk JM, Kelley RK, Gordan JD, Gill RM, Blanchard SC, Ruggero D. PMID: 31478838; PMCID: PMC6776443.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    30. Loss of Fbxw7 synergizes with activated Akt signaling to promote c-Myc dependent cholangiocarcinogenesis. J Hepatol. 2019 10; 71(4):742-752. Wang J, Wang H, Peters M, Ding N, Ribback S, Utpatel K, Cigliano A, Dombrowski F, Xu M, Chen X, Song X, Che L, Evert M, Cossu A, Gordan J, Zeng Y, Chen X, Calvisi DF. PMID: 31195063; PMCID: PMC6773530.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    31. Nivolumab in patients with advanced hepatocellular carcinoma and Child-Pugh class B cirrhosis: Safety and clinical outcomes in a retrospective case series. Cancer. 2019 09 15; 125(18):3234-3241. Thiruvengadam S, Bauer KE, Bracci PM, Keenan BP, Behr SC, Gordan JD, Kelley RK. PMID: 31154669.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    32. KRASG12C inhibition produces a driver-limited state revealing collateral dependencies. Sci Signal. 2019 05 28; 12(583). Lou K, Steri V, Ge AY, Hwang YC, Yogodzinski CH, Shkedi AR, Choi ALM, Mitchell DC, Swaney DL, Hann B, Gordan JD, Shokat KM, Gilbert LA. PMID: 31138768; PMCID: PMC6871662.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    33. MEK inhibition suppresses K-Ras wild-type cholangiocarcinoma in vitro and in vivo via inhibiting cell proliferation and modulating tumor microenvironment. Cell Death Dis. 2019 02 11; 10(2):120. Wang P, Song X, Utpatel K, Shang R, Yang YM, Xu M, Zhang J, Che L, Gordan J, Cigliano A, Seki E, Evert M, Calvisi DF, Hu X, Chen X. PMID: 30741922; PMCID: PMC6370758.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    34. Road map for fibrolamellar carcinoma: progress and goals of a diversified approach. J Hepatocell Carcinoma. 2019; 6:41-48. Kastenhuber ER, Craig J, Ramsey J, Sullivan KM, Sage J, de Oliveira S, Riehle KJ, Scott JD, Gordan JD, Bardeesy N, Abou-Alfa GK. PMID: 30951568; PMCID: PMC6362920.
      View in: PubMed   Mentions: 2  
    35. Translation control of the immune checkpoint in cancer and its therapeutic targeting. Nat Med. 2019 02; 25(2):301-311. Xu Y, Poggio M, Jin HY, Shi Z, Forester CM, Wang Y, Stumpf CR, Xue L, Devericks E, So L, Nguyen HG, Griselin A, Gordan JD, Umetsu SE, Reich SH, Worland ST, Asthana S, Barna M, Webster KR, Cunningham JT, Ruggero D. PMID: 30643286; PMCID: PMC6613562.
      View in: PubMed   Mentions: 125     Fields:    Translation:AnimalsCells
    36. Overexpression-mediated activation of MET in the Golgi promotes HER3/ERBB3 phosphorylation. Oncogene. 2019 03; 38(11):1936-1950. Frazier NM, Brand T, Gordan JD, Grandis J, Jura N. PMID: 30390071; PMCID: PMC6417953.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    37. Combined CDK4/6 and Pan-mTOR Inhibition Is Synergistic Against Intrahepatic Cholangiocarcinoma. Clin Cancer Res. 2019 01 01; 25(1):403-413. Song X, Liu X, Wang H, Wang J, Qiao Y, Cigliano A, Utpatel K, Ribback S, Pilo MG, Serra M, Gordan JD, Che L, Zhang S, Cossu A, Porcu A, Pascale RM, Dombrowski F, Hu H, Calvisi DF, Evert M, Chen X. PMID: 30084835; PMCID: PMC6423983.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    38. Kinome rewiring reveals AURKA limits PI3K-pathway inhibitor efficacy in breast cancer. Nat Chem Biol. 2018 08; 14(8):768-777. Donnella HJ, Webber JT, Levin RS, Camarda R, Momcilovic O, Bayani N, Shah KN, Korkola JE, Shokat KM, Goga A, Gordan JD, Bandyopadhyay S. PMID: 29942081; PMCID: PMC6051919.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    39. Hybrid Capture-Based Tumor Sequencing and Copy Number Analysis to Confirm Origin of Metachronous Metastases in BRCA1-Mutant Cholangiocarcinoma Harboring a Novel YWHAZ-BRAF Fusion. Oncologist. 2018 09; 23(9):998-1003. Lim HC, Montesion M, Botton T, Collisson EA, Umetsu SE, Behr SC, Gordan JD, Stephens PJ, Kelley RK. PMID: 29622700; PMCID: PMC6192605.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    40. Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice. Oncogene. 2018 06; 37(24):3229-3242. Wang J, Dong M, Xu Z, Song X, Zhang S, Qiao Y, Che L, Gordan J, Hu K, Liu Y, Calvisi DF, Chen X. PMID: 29545603; PMCID: PMC6002343.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    41. Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model. Cell Death Dis. 2018 01 18; 9(2):31. Dong M, Liu X, Evert K, Utpatel K, Peters M, Zhang S, Xu Z, Che L, Cigliano A, Ribback S, Dombrowski F, Cossu A, Gordan J, Calvisi DF, Evert M, Liu Y, Chen X. PMID: 29348467; PMCID: PMC5833851.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    42. Sampling strategies to capture single-cell heterogeneity. Nat Methods. 2017 Oct; 14(10):967-970. Rajaram S, Heinrich LE, Gordan JD, Avva J, Bonness KM, Witkiewicz AK, Malter JS, Atreya CE, Warren RS, Wu LF, Altschuler SJ. PMID: 28869755; PMCID: PMC5658002.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    43. Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice. J Hepatol. 2017 12; 67(6):1194-1203. Zhang S, Song X, Cao D, Xu Z, Fan B, Che L, Hu J, Chen B, Dong M, Pilo MG, Cigliano A, Evert K, Ribback S, Dombrowski F, Pascale RM, Cossu A, Vidili G, Porcu A, Simile MM, Pes GM, Giannelli G, Gordan J, Wei L, Evert M, Cong W, Calvisi DF, Chen X. PMID: 28733220; PMCID: PMC5696057.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    44. An Optimized Chromatographic Strategy for Multiplexing In Parallel Reaction Monitoring Mass Spectrometry: Insights from Quantitation of Activated Kinases. Mol Cell Proteomics. 2017 02; 16(2):265-277. Urisman A, Levin RS, Gordan JD, Webber JT, Hernandez H, Ishihama Y, Shokat KM, Burlingame AL. PMID: 27940637; PMCID: PMC5294213.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    45. Synthetic Lethal Targeting of ARID1A-Mutant Ovarian Clear Cell Tumors with Dasatinib. Mol Cancer Ther. 2016 07; 15(7):1472-84. Miller RE, Brough R, Bajrami I, Williamson CT, McDade S, Campbell J, Kigozi A, Rafiq R, Pemberton H, Natrajan R, Joel J, Astley H, Mahoney C, Moore JD, Torrance C, Gordan JD, Webber JT, Levin RS, Shokat KM, Bandyopadhyay S, Lord CJ, Ashworth A. PMID: 27364904.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    46. Isocitrate Dehydrogenase Mutations Confer Dasatinib Hypersensitivity and SRC Dependence in Intrahepatic Cholangiocarcinoma. Cancer Discov. 2016 07; 6(7):727-39. Saha SK, Gordan JD, Kleinstiver BP, Vu P, Najem MS, Yeo JC, Shi L, Kato Y, Levin RS, Webber JT, Damon LJ, Egan RK, Greninger P, McDermott U, Garnett MJ, Jenkins RL, Rieger-Christ KM, Sullivan TB, Hezel AF, Liss AS, Mizukami Y, Goyal L, Ferrone CR, Zhu AX, Joung JK, Shokat KM, Benes CH, Bardeesy N. PMID: 27231123; PMCID: PMC5458737.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimalsCells
    47. Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish. PLoS Genet. 2015 Jul; 11(7):e1005305. Evason KJ, Francisco MT, Juric V, Balakrishnan S, Lopez Pazmino Mdel P, Gordan JD, Kakar S, Spitsbergen J, Goga A, Stainier DY. PMID: 26134322; PMCID: PMC4489858.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    48. Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map. Cancer Discov. 2015 02; 5(2):154-67. Martins MM, Zhou AY, Corella A, Horiuchi D, Yau C, Rakhshandehroo T, Gordan JD, Levin RS, Johnson J, Jascur J, Shales M, Sorrentino A, Cheah J, Clemons PA, Shamji AF, Schreiber SL, Krogan NJ, Shokat KM, McCormick F, Goga A, Bandyopadhyay S. PMID: 25501949; PMCID: PMC4407699.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    49. Oncogene mimicry as a mechanism of primary resistance to BRAF inhibitors. Cell Rep. 2014 Aug 21; 8(4):1037-48. Sos ML, Levin RS, Gordan JD, Oses-Prieto JA, Webber JT, Salt M, Hann B, Burlingame AL, McCormick F, Bandyopadhyay S, Shokat KM. PMID: 25127139; PMCID: PMC4294625.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    50. Integrative genomic analyses of sporadic clear cell renal cell carcinoma define disease subtypes and potential new therapeutic targets. Cancer Res. 2012 Jan 01; 72(1):112-21. Dondeti VR, Wubbenhorst B, Lal P, Gordan JD, D'Andrea K, Attiyeh EF, Simon MC, Nathanson KL. PMID: 22094876; PMCID: PMC3251639.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    51. "And what other medications are you taking?". J Clin Oncol. 2011 Apr 10; 29(11):e288-91. Gordan JD, Chay WY, Kelley RK, Ko AH, Choo SP, Venook AP. PMID: 21245436.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    52. HIF2alpha inhibition promotes p53 pathway activity, tumor cell death, and radiation responses. Proc Natl Acad Sci U S A. 2009 Aug 25; 106(34):14391-6. Bertout JA, Majmundar AJ, Gordan JD, Lam JC, Ditsworth D, Keith B, Brown EJ, Nathanson KL, Simon MC. PMID: 19706526; PMCID: PMC2726037.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansCells
    53. Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma. Oncogene. 2009 Jul 09; 28(27):2513-23. Wright TM, Brannon AR, Gordan JD, Mikels AJ, Mitchell C, Chen S, Espinosa I, van de Rijn M, Pruthi R, Wallen E, Edwards L, Nusse R, Rathmell WK. PMID: 19448672; PMCID: PMC2771692.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    54. HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma. Cancer Cell. 2008 Dec 09; 14(6):435-46. Gordan JD, Lal P, Dondeti VR, Letrero R, Parekh KN, Oquendo CE, Greenberg RA, Flaherty KT, Rathmell WK, Keith B, Simon MC, Nathanson KL. PMID: 19061835; PMCID: PMC2621440.
      View in: PubMed   Mentions: 283     Fields:    Translation:HumansCells
    55. Hypoxia-mediated selective mRNA translation by an internal ribosome entry site-independent mechanism. J Biol Chem. 2008 Jun 13; 283(24):16309-19. Young RM, Wang SJ, Gordan JD, Ji X, Liebhaber SA, Simon MC. PMID: 18430730; PMCID: PMC2423241.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    56. HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferation. Cancer Cell. 2007 Aug; 12(2):108-13. Gordan JD, Thompson CB, Simon MC. PMID: 17692803; PMCID: PMC3215289.
      View in: PubMed   Mentions: 405     Fields:    Translation:HumansCells
    57. The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis. Genes Dev. 2007 May 01; 21(9):1037-49. Lum JJ, Bui T, Gruber M, Gordan JD, DeBerardinis RJ, Covello KL, Simon MC, Thompson CB. PMID: 17437992; PMCID: PMC1855230.
      View in: PubMed   Mentions: 211     Fields:    Translation:AnimalsCells
    58. HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity. Cancer Cell. 2007 Apr; 11(4):335-47. Gordan JD, Bertout JA, Hu CJ, Diehl JA, Simon MC. PMID: 17418410; PMCID: PMC3145406.
      View in: PubMed   Mentions: 423     Fields:    Translation:HumansAnimalsCells
    59. Hypoxia-inducible factors: central regulators of the tumor phenotype. Curr Opin Genet Dev. 2007 Feb; 17(1):71-7. Gordan JD, Simon MC. PMID: 17208433; PMCID: PMC3215290.
      View in: PubMed   Mentions: 218     Fields:    Translation:Humans
    60. Ribosomal stress couples the unfolded protein response to p53-dependent cell cycle arrest. J Biol Chem. 2006 Oct 06; 281(40):30036-45. Zhang F, Hamanaka RB, Bobrovnikova-Marjon E, Gordan JD, Dai MS, Lu H, Simon MC, Diehl JA. PMID: 16893887.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    61. HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev. 2006 Mar 01; 20(5):557-70. Covello KL, Kehler J, Yu H, Gordan JD, Arsham AM, Hu CJ, Labosky PA, Simon MC, Keith B. PMID: 16510872; PMCID: PMC1410808.
      View in: PubMed   Mentions: 375     Fields:    Translation:AnimalsCells
    62. ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation. J Exp Med. 2004 Oct 18; 200(8):1063-74. Wang H, McCann FE, Gordan JD, Wu X, Raab M, Malik TH, Davis DM, Rudd CE. PMID: 15477347; PMCID: PMC2211848.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    63. The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase. Mol Cell Biol. 2004 Oct; 24(19):8477-86. Cullinan SB, Gordan JD, Jin J, Harper JW, Diehl JA. PMID: 15367669; PMCID: PMC516753.
      View in: PubMed   Mentions: 441     Fields:    Translation:AnimalsCells
    64. Universal tumor antigens as targets for immunotherapy. Cytotherapy. 2002; 4(4):317-27. Gordan JD, Vonderheide RH. PMID: 12396831.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    65. Antigens recognized by autologous antibody in patients with renal-cell carcinoma. Int J Cancer. 1999 Nov 12; 83(4):456-64. Scanlan MJ, Gordan JD, Williamson B, Stockert E, Bander NH, Jongeneel V, Gure AO, Jäger D, Jäger E, Knuth A, Chen YT, Old LJ. PMID: 10508479.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    66. Isoforms of the human PDZ-73 protein exhibit differential tissue expression. Biochim Biophys Acta. 1999 Apr 14; 1445(1):39-52. Scanlan MJ, Williamson B, Jungbluth A, Stockert E, Arden KC, Viars CS, Gure AO, Gordan JD, Chen YT, Old LJ. PMID: 10209257.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    67. Aspects of GnRH neurobiology conserved across vertebrate forms. Gen Comp Endocrinol. 1998 Dec; 112(3):276-82. Dellovade T, Schwanzel-Fukuda M, Gordan J, Pfaff D. PMID: 9843633.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    68. Characterization of human colon cancer antigens recognized by autologous antibodies. Int J Cancer. 1998 May 29; 76(5):652-8. Scanlan MJ, Chen YT, Williamson B, Gure AO, Stockert E, Gordan JD, Türeci O, Sahin U, Pfreundschuh M, Old LJ. PMID: 9610721.
      View in: PubMed   Mentions: 84     Fields:    Translation:Humans
    69. Mathematical exploration of pulsatility in cultured gonadotropin-releasing hormone neurons. Neuroendocrinology. 1998 Jan; 67(1):2-17. Gordan JD, Attardi BJ, Pfaff DW. PMID: 9485164.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    70. Reproductive functions illustrating direct and indirect effects of genes on behavior. Horm Behav. 1996 Dec; 30(4):487-94. Ogawa S, Gordan JD, Taylor J, Lubahn D, Korach K, Pfaff DW. PMID: 9047273.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    71. Initial preparation of the periodontally advanced dentition. J Calif Dent Assoc. 1989 Sep; 17(9):25-8. Yang LR, Gordan J. PMID: 2484068.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
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