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Balyn Zaro, PhD

Title(s)Assistant Professor, Pharmaceutical Chemistry
SchoolSchool of Pharmacy
Phone415-514-9219
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    Collapse Biography 
    Collapse Education and Training
    Stanford School of Medicine, Stanford, CA08/2019Stem Cell Biology and Innate Immunity
    Scripps Research Institute, La Jolla, CA08/2017Chemical Biology
    University of Southern California, Los Angeles, CAPh.D.08/2014Chemical Biology
    University of Southern California, Los Angeles, CAB.S.06/2009Chemistry

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Barkal AA, Brewer RE, Markovic M, Kowarsky M, Barkal SA, Zaro BW, Krishnan V, Hatakeyama J, Dorigo O, Barkal LJ, Weissman IL. CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy. Nature. 2019 Aug; 572(7769):392-396. PMID: 31367043.
      View in: PubMed
    2. Senkane K, Vinogradova EV, Suciu RM, Crowley VM, Zaro BW, Bradshaw JM, Brameld KA, Cravatt BF. The Proteome-Wide Potential for Reversible Covalency at Cysteine. Angew Chem Int Ed Engl. 2019 Aug 12; 58(33):11385-11389. PMID: 31222866.
      View in: PubMed
    3. Zaro BW, Vinogradova EV, Lazar DC, Blewett MM, Suciu RM, Takaya J, Studer S, de la Torre JC, Casanova JL, Cravatt BF, Teijaro JR. Dimethyl Fumarate Disrupts Human Innate Immune Signaling by Targeting the IRAK4-MyD88 Complex. J Immunol. 2019 May 01; 202(9):2737-2746. PMID: 30885957.
      View in: PubMed
    4. Walter LA, Batt AR, Darabedian N, Zaro BW, Pratt MR. Azide- and Alkyne-Bearing Metabolic Chemical Reporters of Glycosylation Show Structure-Dependent Feedback Inhibition of the Hexosamine Biosynthetic Pathway. Chembiochem. 2018 09 17; 19(18):1918-1921. PMID: 29979493.
      View in: PubMed
    5. Bateman LA, Zaro BW, Miller SM, Pratt MR. Correction to "An Alkyne-Aspirin Chemical Reporter for the Detection of Aspirin-Dependent Protein Modification in Living Cells". J Am Chem Soc. 2018 04 11; 140(14):4954. PMID: 29589917.
      View in: PubMed
    6. Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR. The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8. J Am Chem Soc. 2017 06 14; 139(23):7872-7885. PMID: 28528544.
      View in: PubMed
    7. Batt AR, Zaro BW, Navarro MX, Pratt MR. Metabolic Chemical Reporters of Glycans Exhibit Cell-Type-Selective Metabolism and Glycoprotein Labeling. Chembiochem. 2017 07 04; 18(13):1177-1182. PMID: 28231413.
      View in: PubMed
    8. Zaro BW, Batt AR, Chuh KN, Navarro MX, Pratt MR. The Small Molecule 2-Azido-2-deoxy-glucose Is a Metabolic Chemical Reporter of O-GlcNAc Modifications in Mammalian Cells, Revealing an Unexpected Promiscuity of O-GlcNAc Transferase. ACS Chem Biol. 2017 03 17; 12(3):787-794. PMID: 28135057.
      View in: PubMed
    9. Zaro BW, Whitby LR, Lum KM, Cravatt BF. Metabolically Labile Fumarate Esters Impart Kinetic Selectivity to Irreversible Inhibitors. J Am Chem Soc. 2016 12 14; 138(49):15841-15844. PMID: 27960302.
      View in: PubMed
    10. Blewett MM, Xie J, Zaro BW, Backus KM, Altman A, Teijaro JR, Cravatt BF. Chemical proteomic map of dimethyl fumarate-sensitive cysteines in primary human T cells. Sci Signal. 2016 09 13; 9(445):rs10. PMID: 27625306.
      View in: PubMed
    11. Marotta NP, Lin YH, Lewis YE, Ambroso MR, Zaro BW, Roth MT, Arnold DB, Langen R, Pratt MR. O-GlcNAc modification blocks the aggregation and toxicity of the protein a-synuclein associated with Parkinson's disease. Nat Chem. 2015 Nov; 7(11):913-20. PMID: 26492012.
      View in: PubMed
    12. Chesarino NM, Hach JC, Chen JL, Zaro BW, Rajaram MV, Turner J, Schlesinger LS, Pratt MR, Hang HC, Yount JS. Chemoproteomics reveals Toll-like receptor fatty acylation. BMC Biol. 2014 Nov 05; 12:91. PMID: 25371237.
      View in: PubMed
    13. Chuh KN, Zaro BW, Piller F, Piller V, Pratt MR. Changes in metabolic chemical reporter structure yield a selective probe of O-GlcNAc modification. J Am Chem Soc. 2014 Sep 03; 136(35):12283-95. PMID: 25153642.
      View in: PubMed
    14. Zaro BW, Chuh KN, Pratt MR. Chemical reporter for visualizing metabolic cross-talk between carbohydrate metabolism and protein modification. ACS Chem Biol. 2014 Sep 19; 9(9):1991-6. PMID: 25062036.
      View in: PubMed
    15. Gurel Z, Zaro BW, Pratt MR, Sheibani N. Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy. PLoS One. 2014; 9(5):e95561. PMID: 24788674.
      View in: PubMed
    16. Bateman LA, Zaro BW, Miller SM, Pratt MR. An alkyne-aspirin chemical reporter for the detection of aspirin-dependent protein modification in living cells. J Am Chem Soc. 2013 Oct 02; 135(39):14568-73. PMID: 23998633.
      View in: PubMed
    17. Zaro BW, Hang HC, Pratt MR. Incorporation of unnatural sugars for the identification of glycoproteins. Methods Mol Biol. 2013; 951:57-67. PMID: 23296524.
      View in: PubMed
    18. Bateman LA, Zaro BW, Chuh KN, Pratt MR. N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation. Chem Commun (Camb). 2013 May 14; 49(39):4328-30. PMID: 23235740.
      View in: PubMed
    19. Zaro BW, Yang YY, Hang HC, Pratt MR. Chemical reporters for fluorescent detection and identification of O-GlcNAc-modified proteins reveal glycosylation of the ubiquitin ligase NEDD4-1. Proc Natl Acad Sci U S A. 2011 May 17; 108(20):8146-51. PMID: 21540332.
      View in: PubMed
    20. Zaro BW, Bateman LA, Pratt MR. Robust in-gel fluorescence detection of mucin-type O-linked glycosylation. Bioorg Med Chem Lett. 2011 Sep 01; 21(17):5062-6. PMID: 21531554.
      View in: PubMed
    21. Lau HD, Yaegashi J, Zaro BW, Pratt MR. Precise control of protein concentration in living cells. Angew Chem Int Ed Engl. 2010 Nov 02; 49(45):8458-61. PMID: 20878685.
      View in: PubMed
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