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Jesse Nussbaum, MD

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
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    Duke UniversityM.D.2004School of Medicine

    Collapse Research 
    Collapse Research Activities and Funding
    Interaction between innate and Th2 lymphocytes in helminth immunity
    NIH/NIAID K08AI113143Jun 1, 2014 - May 31, 2019
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Schneider C, Lee J, Koga S, Ricardo-Gonzalez RR, Nussbaum JC, Smith LK, Villeda SA, Liang HE, Locksley RM. Tissue-Resident Group 2 Innate Lymphoid Cells Differentiate by Layered Ontogeny and In Situ Perinatal Priming. Immunity. 2019 06 18; 50(6):1425-1438.e5. PMID: 31128962.
      View in: PubMed
    2. Ricardo-Gonzalez RR, Van Dyken SJ, Schneider C, Lee J, Nussbaum JC, Liang HE, Vaka D, Eckalbar WL, Molofsky AB, Erle DJ, Locksley RM. Tissue signals imprint ILC2 identity with anticipatory function. Nat Immunol. 2018 10; 19(10):1093-1099. PMID: 30201992.
      View in: PubMed
    3. J. Lee, C. Schneider, H. Liang, R. Ricardo-Gonzalez, J. Nussbaum, L. Smith, S. Villeda, R. Locksley. 1021 Origin of type 2 innate lymphoid cells in the skin. Journal of Investigative Dermatology. 2018 May 1; 138(5):s173.
      View in: Publisher Site
    4. Nussbaum JC, Ortiz-Carpena JF. Isolation and Identification of Group 2 Innate Lymphoid Cells in Settings of Type 2 Inflammation. Methods Mol Biol. 2018; 1799:93-107. PMID: 29956147.
      View in: PubMed
    5. R. Ricardo-Gonzalez, S. Van Dyken, A. Molofsky, J. Nussbaum, J. Lee, R. Locksley. LB973 Characterization of tissue-resident ILC2 heterogeneity in homeostasis. Journal of Investigative Dermatology. 2017 Oct 1; 137(10):b8.
      View in: Publisher Site
    6. Van Dyken SJ, Nussbaum JC, Lee J, Molofsky AB, Liang HE, Pollack JL, Gate RE, Haliburton GE, Ye CJ, Marson A, Erle DJ, Locksley RM. A tissue checkpoint regulates type 2 immunity. Nat Immunol. 2016 Dec; 17(12):1381-1387. PMID: 27749840.
      View in: PubMed
    7. Hindi SM, Wang Y, Jones KD, Nussbaum JC, Chang Y, Masharani U, Bikle D, Shoback DM, Hsiao EC. A Case of Hypercalcemia and Overexpression of CYP27B1 in Skeletal Muscle Lesions in a Patient with HIV Infection After Cosmetic Injections with Polymethylmethacrylate (PMMA) for Wasting. Calcif Tissue Int. 2015 Dec; 97(6):634-9. PMID: 26253396.
      View in: PubMed
    8. Mohapatra A, Van Dyken SJ, Schneider C, Nussbaum JC, Liang HE, Locksley RM. Group 2 innate lymphoid cells utilize the IRF4-IL-9 module to coordinate epithelial cell maintenance of lung homeostasis. Mucosal Immunol. 2016 Jan; 9(1):275-86. PMID: 26129648.
      View in: PubMed
    9. Molofsky AB, Van Gool F, Liang HE, Van Dyken SJ, Nussbaum JC, Lee J, Bluestone JA, Locksley RM. Interleukin-33 and Interferon-? Counter-Regulate Group 2 Innate Lymphoid Cell Activation during Immune Perturbation. Immunity. 2015 Jul 21; 43(1):161-74. PMID: 26092469.
      View in: PubMed
    10. Lee MW, Odegaard JI, Mukundan L, Qiu Y, Molofsky AB, Nussbaum JC, Yun K, Locksley RM, Chawla A. Activated type 2 innate lymphoid cells regulate beige fat biogenesis. Cell. 2015 Jan 15; 160(1-2):74-87. PMID: 25543153.
      View in: PubMed
    11. Van Dyken SJ, Mohapatra A, Nussbaum JC, Molofsky AB, Thornton EE, Ziegler SF, McKenzie AN, Krummel MF, Liang HE, Locksley RM. Chitin activates parallel immune modules that direct distinct inflammatory responses via innate lymphoid type 2 and ?d T cells. Immunity. 2014 Mar 20; 40(3):414-24. PMID: 24631157.
      View in: PubMed
    12. Jarvis JN, Bicanic T, Loyse A, Namarika D, Jackson A, Nussbaum JC, Longley N, Muzoora C, Phulusa J, Taseera K, Kanyembe C, Wilson D, Hosseinipour MC, Brouwer AE, Limmathurotsakul D, White N, van der Horst C, Wood R, Meintjes G, Bradley J, Jaffar S, Harrison T. Determinants of mortality in a combined cohort of 501 patients with HIV-associated Cryptococcal meningitis: implications for improving outcomes. Clin Infect Dis. 2014 Mar; 58(5):736-45. PMID: 24319084.
      View in: PubMed
    13. Nussbaum JC, Van Dyken SJ, von Moltke J, Cheng LE, Mohapatra A, Molofsky AB, Thornton EE, Krummel MF, Chawla A, Liang HE, Locksley RM. Type 2 innate lymphoid cells control eosinophil homeostasis. Nature. 2013 Oct 10; 502(7470):245-8. PMID: 24037376.
      View in: PubMed
    14. Steven J. Van Dyken, Alexander Mohapatra, Jesse C. Nussbaum, Hong-Erh Liang, Richard M. Locksley. 265 Cooperative activation of innate lymphoid type 2 cells (ILC2) by epithelial cytokines in response to chitin. Cytokine. 2013 Sep 1; 63(3):306.
      View in: Publisher Site
    15. Bando JK, Nussbaum JC, Liang HE, Locksley RM. Type 2 innate lymphoid cells constitutively express arginase-I in the naive and inflamed lung. J Leukoc Biol. 2013 Nov; 94(5):877-84. PMID: 23924659.
      View in: PubMed
    16. Molofsky AB, Nussbaum JC, Liang HE, Van Dyken SJ, Cheng LE, Mohapatra A, Chawla A, Locksley RM. Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages. J Exp Med. 2013 Mar 11; 210(3):535-49. PMID: 23420878.
      View in: PubMed
    17. Jackson AT, Nussbaum JC, Phulusa J, Namarika D, Chikasema M, Kanyemba C, Jarvis JN, Jaffar S, Hosseinipour MC, van der Horst C, Harrison TS. A phase II randomized controlled trial adding oral flucytosine to high-dose fluconazole, with short-course amphotericin B, for cryptococcal meningitis. AIDS. 2012 Jul 17; 26(11):1363-70. PMID: 22526517.
      View in: PubMed
    18. Nussbaum JC, Locksley RM. Infectious (Non)tolerance--frustrated commensalism gone awry? Cold Spring Harb Perspect Biol. 2012 May 01; 4(5). PMID: 22456498.
      View in: PubMed
    19. Nussbaum JC, Jackson A, Namarika D, Phulusa J, Kenala J, Kanyemba C, Jarvis JN, Jaffar S, Hosseinipour MC, Kamwendo D, van der Horst CM, Harrison TS. Combination flucytosine and high-dose fluconazole compared with fluconazole monotherapy for the treatment of cryptococcal meningitis: a randomized trial in Malawi. Clin Infect Dis. 2010 Feb 01; 50(3):338-44. PMID: 20038244.
      View in: PubMed
    20. Idnurm A, Reedy JL, Nussbaum JC, Heitman J. Cryptococcus neoformans virulence gene discovery through insertional mutagenesis. Eukaryot Cell. 2004 Apr; 3(2):420-9. PMID: 15075272.
      View in: PubMed
    21. de Jesús-Berríos M, Liu L, Nussbaum JC, Cox GM, Stamler JS, Heitman J. Enzymes that counteract nitrosative stress promote fungal virulence. Curr Biol. 2003 Nov 11; 13(22):1963-8. PMID: 14614821.
      View in: PubMed
    22. Touchman JW, Bouffard GG, Weintraub LA, Idol JR, Wang L, Robbins CM, Nussbaum JC, Lovett M, Green ED. 2006 expressed-sequence tags derived from human chromosome 7-enriched cDNA libraries. Genome Res. 1997 Mar; 7(3):281-92. PMID: 9074931.
      View in: PubMed