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Martin Valdearcos Contreras, PhD

Address513 Parnassus Ave, Med Sci
San Francisco CA 94143
Phone415-476-9847
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Valdearcos M, Douglass JD, Robblee MM, Dorfman MD, Stifler DR, Bennett ML, Gerritse I, Fasnacht R, Barres BA, Thaler JP, Koliwad SK. Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility. Cell Metab. 2017 Jul 05; 26(1):185-197.e3. PMID: 28683286.
      View in: PubMed
    2. Yulyaningsih E, Rudenko IA, Valdearcos M, Dahlén E, Vagena E, Chan A, Alvarez-Buylla A, Vaisse C, Koliwad SK, Xu AW. Acute Lesioning and Rapid Repair of Hypothalamic Neurons outside the Blood-Brain Barrier. Cell Rep. 2017 Jun 13; 19(11):2257-2271. PMID: 28614713.
      View in: PubMed
    3. Feng X, Valdearcos M, Uchida Y, Lutrin D, Maze M, Koliwad SK. Microglia mediate postoperative hippocampal inflammation and cognitive decline in mice. JCI Insight. 2017 Apr 06; 2(7):e91229. PMID: 28405620.
      View in: PubMed
    4. Peña L, Meana C, Astudillo AM, Lordén G, Valdearcos M, Sato H, Murakami M, Balsinde J, Balboa MA. Critical role for cytosolic group IVA phospholipase A2 in early adipocyte differentiation and obesity. Biochim Biophys Acta. 2016 09; 1861(9 Pt A):1083-1095. PMID: 27317983.
      View in: PubMed
    5. Robblee MM, Kim CC, Porter Abate J, Valdearcos M, Sandlund KL, Shenoy MK, Volmer R, Iwawaki T, Koliwad SK. Saturated Fatty Acids Engage an IRE1a-Dependent Pathway to Activate the NLRP3 Inflammasome in Myeloid Cells. Cell Rep. 2016 Mar 22; 14(11):2611-23. PMID: 26971994.
      View in: PubMed
    6. Rottkamp DM, Rudenko IA, Maier MT, Roshanbin S, Yulyaningsih E, Perez L, Valdearcos M, Chua S, Koliwad SK, Xu AW. Leptin potentiates astrogenesis in the developing hypothalamus. Mol Metab. 2015 Nov; 4(11):881-9. PMID: 26629411; PMCID: PMC4632125.
    7. Valdearcos M, Xu AW, Koliwad SK. Hypothalamic inflammation in the control of metabolic function. Annu Rev Physiol. 2015; 77:131-60. PMID: 25668019.
      View in: PubMed
    8. Valdearcos M, Robblee MM, Benjamin DI, Nomura DK, Xu AW, Koliwad SK. Microglia dictate the impact of saturated fat consumption on hypothalamic inflammation and neuronal function. Cell Rep. 2014 Dec 24; 9(6):2124-38. PMID: 25497089; PMCID: PMC4617309.
    9. Meana C, Peña L, Lordén G, Esquinas E, Guijas C, Valdearcos M, Balsinde J, Balboa MA. Lipin-1 integrates lipid synthesis with proinflammatory responses during TLR activation in macrophages. J Immunol. 2014 Nov 01; 193(9):4614-22. PMID: 25252959.
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    10. Valdearcos M, Esquinas E, Meana C, Peña L, Gil-de-Gómez L, Balsinde J, Balboa MA. Lipin-2 reduces proinflammatory signaling induced by saturated fatty acids in macrophages. J Biol Chem. 2012 Mar 30; 287(14):10894-904. PMID: 22334674; PMCID: PMC3322858.
    11. Valdearcos M, Esquinas E, Meana C, Gil-de-Gómez L, Guijas C, Balsinde J, Balboa MA. Subcellular localization and role of lipin-1 in human macrophages. J Immunol. 2011 May 15; 186(10):6004-13. PMID: 21478406.
      View in: PubMed
    12. Casas J, Valdearcos M, Pindado J, Balsinde J, Balboa MA. The cationic cluster of group IVA phospholipase A2 (Lys488/Lys541/Lys543/Lys544) is involved in translocation of the enzyme to phagosomes in human macrophages. J Lipid Res. 2010 Feb; 51(2):388-99. PMID: 19717620; PMCID: PMC2803241.
    13. Casas J, Meana C, Esquinas E, Valdearcos M, Pindado J, Balsinde J, Balboa MA. Requirement of JNK-mediated phosphorylation for translocation of group IVA phospholipase A2 to phagosomes in human macrophages. J Immunol. 2009 Aug 15; 183(4):2767-74. PMID: 19625654.
      View in: PubMed
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